Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | biogenic amine receptor | 0.0038 | 0.1467 | 0.1467 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0038 | 0.1467 | 0.1467 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0038 | 0.1467 | 0.5 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0038 | 0.1467 | 0.1635 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Brugia malayi | AKH receptor | 0.0038 | 0.1467 | 0.1635 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0038 | 0.1467 | 0.1635 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0038 | 0.1467 | 0.1467 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0033 | 0.1028 | 0.1145 |
Echinococcus granulosus | orexin receptor type 2 | 0.0038 | 0.1467 | 0.1635 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0038 | 0.1467 | 0.1635 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0108 | 0.8236 | 1 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0038 | 0.1467 | 0.1635 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0038 | 0.1467 | 0.1635 |
Schistosoma mansoni | biogenic amine receptor | 0.0038 | 0.1467 | 0.1467 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0038 | 0.1467 | 0.1635 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Brugia malayi | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0038 | 0.1467 | 0.1635 |
Brugia malayi | Melatonin receptor type 1A | 0.0038 | 0.1467 | 0.1635 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0038 | 0.1467 | 0.1635 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0033 | 0.1028 | 0.1145 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0038 | 0.1467 | 0.1635 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0038 | 0.1467 | 0.1467 |
Onchocerca volvulus | 0.0038 | 0.1467 | 0.5 | |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0038 | 0.1467 | 0.1635 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0038 | 0.1467 | 0.1467 |
Echinococcus multilocularis | somatostatin receptor | 0.0038 | 0.1467 | 0.1635 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0038 | 0.1467 | 0.1467 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Brugia malayi | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Echinococcus granulosus | allatostatin A receptor | 0.0038 | 0.1467 | 0.1635 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0038 | 0.1467 | 0.1635 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0038 | 0.1467 | 0.1635 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0038 | 0.1467 | 0.1635 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0038 | 0.1467 | 0.1635 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0038 | 0.1467 | 0.1635 |
Echinococcus multilocularis | voltage gated potassium channel | 0.0033 | 0.1028 | 0.1145 |
Echinococcus granulosus | neuropeptide receptor | 0.0038 | 0.1467 | 0.1635 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0038 | 0.1467 | 0.1467 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Brugia malayi | ORL1-like opioid receptor | 0.0038 | 0.1467 | 0.1635 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0038 | 0.1467 | 0.1635 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0038 | 0.1467 | 0.1467 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0038 | 0.1467 | 0.1635 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.1467 | 0.1467 |
Brugia malayi | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0038 | 0.1467 | 0.1635 |
Brugia malayi | Serotonin receptor | 0.0038 | 0.1467 | 0.1635 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0038 | 0.1467 | 0.1635 |
Onchocerca volvulus | 0.0038 | 0.1467 | 0.5 | |
Echinococcus granulosus | neuropeptide s receptor | 0.0038 | 0.1467 | 0.1635 |
Echinococcus multilocularis | neuropeptide receptor | 0.0038 | 0.1467 | 0.1635 |
Onchocerca volvulus | 0.0038 | 0.1467 | 0.5 | |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0038 | 0.1467 | 0.1635 |
Onchocerca volvulus | 0.0038 | 0.1467 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Brugia malayi | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Schistosoma mansoni | neuropeptide receptor | 0.0038 | 0.1467 | 0.1467 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Echinococcus multilocularis | serotonin receptor | 0.0038 | 0.1467 | 0.1635 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0038 | 0.1467 | 0.1635 |
Echinococcus granulosus | g protein coupled receptor | 0.0038 | 0.1467 | 0.1635 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0038 | 0.1467 | 0.1467 |
Echinococcus granulosus | sex peptide receptor | 0.0038 | 0.1467 | 0.1635 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0038 | 0.1467 | 0.1635 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0038 | 0.1467 | 0.1635 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Echinococcus multilocularis | sex peptide receptor | 0.0038 | 0.1467 | 0.1635 |
Schistosoma mansoni | amine GPCR | 0.0038 | 0.1467 | 0.1467 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0038 | 0.1467 | 0.1635 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Brugia malayi | G protein-coupled receptor | 0.0038 | 0.1467 | 0.1635 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0038 | 0.1467 | 0.1635 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0038 | 0.1467 | 0.1467 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0038 | 0.1467 | 0.1635 |
Onchocerca volvulus | 0.0038 | 0.1467 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0116 | 0.8972 | 1 |
Echinococcus granulosus | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Brugia malayi | neuropeptide F receptor | 0.0038 | 0.1467 | 0.1635 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0038 | 0.1467 | 0.1635 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0038 | 0.1467 | 0.1635 |
Onchocerca volvulus | 0.0038 | 0.1467 | 0.5 | |
Echinococcus multilocularis | allatostatin A receptor | 0.0038 | 0.1467 | 0.1635 |
Schistosoma mansoni | adenoreceptor | 0.0038 | 0.1467 | 0.1467 |
Schistosoma mansoni | neuropeptide receptor | 0.0038 | 0.1467 | 0.1467 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0038 | 0.1467 | 0.1635 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0038 | 0.1467 | 0.1635 |
Echinococcus multilocularis | g protein coupled receptor | 0.0038 | 0.1467 | 0.1635 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0038 | 0.1467 | 0.1635 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0038 | 0.1467 | 0.1635 |
Schistosoma mansoni | opsin-like receptor | 0.0038 | 0.1467 | 0.1467 |
Brugia malayi | Dopamine receptor | 0.0038 | 0.1467 | 0.1635 |
Brugia malayi | G-protein coupled receptor | 0.0038 | 0.1467 | 0.1635 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0038 | 0.1467 | 0.1635 |
Onchocerca volvulus | 0.0038 | 0.1467 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Schistosoma mansoni | neuropeptide receptor | 0.0038 | 0.1467 | 0.1467 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0038 | 0.1467 | 0.1467 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0033 | 0.1028 | 0.1028 |
Schistosoma mansoni | amine GPCR | 0.0038 | 0.1467 | 0.1467 |
Echinococcus granulosus | somatostatin receptor | 0.0038 | 0.1467 | 0.1635 |
Onchocerca volvulus | 0.0038 | 0.1467 | 0.5 | |
Echinococcus multilocularis | orexin receptor type 2 | 0.0038 | 0.1467 | 0.1635 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0038 | 0.1467 | 0.1635 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0038 | 0.1467 | 0.1635 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0038 | 0.1467 | 0.1635 |
Brugia malayi | follicle stimulating hormone receptor | 0.0038 | 0.1467 | 0.1635 |
Brugia malayi | putative neuropeptide receptor | 0.0038 | 0.1467 | 0.1635 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0116 | 0.8972 | 1 |
Echinococcus multilocularis | g protein coupled receptor | 0.0038 | 0.1467 | 0.1635 |
Onchocerca volvulus | 0.0038 | 0.1467 | 0.5 | |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.1467 | 0.1467 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0038 | 0.1467 | 0.1635 |
Brugia malayi | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Brugia malayi | Dopamine receptor protein 1 | 0.0038 | 0.1467 | 0.1635 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0038 | 0.1467 | 0.1635 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0038 | 0.1467 | 0.1635 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0038 | 0.1467 | 0.1635 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0038 | 0.1467 | 0.1635 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0038 | 0.1467 | 0.1635 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0033 | 0.1028 | 0.1028 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0038 | 0.1467 | 0.1635 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0038 | 0.1467 | 0.1635 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0038 | 0.1467 | 0.1635 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Echinococcus multilocularis | fmrfamide receptor | 0.0038 | 0.1467 | 0.1635 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0038 | 0.1467 | 0.1635 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0038 | 0.1467 | 0.1467 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0038 | 0.1467 | 0.1635 |
Schistosoma mansoni | myosin xvIII | 0.0038 | 0.1467 | 0.1467 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0038 | 0.1467 | 0.1467 |
Onchocerca volvulus | 0.0038 | 0.1467 | 0.5 | |
Onchocerca volvulus | 0.0038 | 0.1467 | 0.5 | |
Echinococcus multilocularis | serotonin receptor | 0.0038 | 0.1467 | 0.1635 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0108 | 0.8236 | 1 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0038 | 0.1467 | 0.1635 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0038 | 0.1467 | 0.1635 |
Brugia malayi | Dopamine receptor protein 2 | 0.0038 | 0.1467 | 0.1635 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0038 | 0.1467 | 0.1467 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0038 | 0.1467 | 0.1635 |
Schistosoma mansoni | biogenic amine receptor | 0.0038 | 0.1467 | 0.1467 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Brugia malayi | GnHR receptor homolog | 0.0038 | 0.1467 | 0.1635 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0038 | 0.1467 | 0.1467 |
Brugia malayi | larval opioid receptor | 0.0038 | 0.1467 | 0.1635 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0038 | 0.1467 | 0.1635 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0038 | 0.1467 | 0.1467 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0038 | 0.1467 | 0.1635 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0038 | 0.1467 | 0.1635 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0038 | 0.1467 | 0.1635 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0038 | 0.1467 | 0.1467 |
Schistosoma mansoni | neuropeptide receptor | 0.0038 | 0.1467 | 0.1467 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.1467 | 0.1467 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0116 | 0.8972 | 1 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0038 | 0.1467 | 0.1635 |
Echinococcus multilocularis | fmrfamide receptor | 0.0038 | 0.1467 | 0.1635 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0038 | 0.1467 | 0.1467 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0038 | 0.1467 | 0.1467 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0038 | 0.1467 | 0.1635 |
Brugia malayi | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0038 | 0.1467 | 0.1635 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0038 | 0.1467 | 0.1467 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0038 | 0.1467 | 0.1635 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Brugia malayi | neuropeptide F receptor | 0.0038 | 0.1467 | 0.1635 |
Echinococcus multilocularis | g protein coupled receptor | 0.0038 | 0.1467 | 0.1635 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0038 | 0.1467 | 0.1635 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0038 | 0.1467 | 0.1635 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0038 | 0.1467 | 0.1635 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0038 | 0.1467 | 0.1635 |
Brugia malayi | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0038 | 0.1467 | 0.1635 |
Echinococcus granulosus | g-protein coupled receptor | 0.0038 | 0.1467 | 0.1635 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Brugia malayi | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0038 | 0.1467 | 0.1635 |
Brugia malayi | G-protein coupled receptor | 0.0038 | 0.1467 | 0.1635 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0038 | 0.1467 | 0.1635 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0038 | 0.1467 | 0.1635 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0038 | 0.1467 | 0.1635 |
Echinococcus granulosus | g protein coupled receptor | 0.0038 | 0.1467 | 0.1635 |
Brugia malayi | Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog | 0.0033 | 0.1028 | 0.1145 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0038 | 0.1467 | 0.1635 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0038 | 0.1467 | 0.1635 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Echinococcus granulosus | fmrfamide receptor | 0.0038 | 0.1467 | 0.1635 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.1467 | 0.1467 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0038 | 0.1467 | 0.1635 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0038 | 0.1467 | 0.1467 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0038 | 0.1467 | 0.1467 |
Echinococcus multilocularis | neuropeptide receptor | 0.0038 | 0.1467 | 0.1635 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0038 | 0.1467 | 0.1635 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0038 | 0.1467 | 0.1635 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0038 | 0.1467 | 0.1635 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Schistosoma mansoni | amine GPCR | 0.0038 | 0.1467 | 0.1467 |
Onchocerca volvulus | 0.0038 | 0.1467 | 0.5 | |
Brugia malayi | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0038 | 0.1467 | 0.1635 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0038 | 0.1467 | 0.1635 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Onchocerca volvulus | 0.0038 | 0.1467 | 0.5 | |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0038 | 0.1467 | 0.1467 |
Schistosoma mansoni | amine GPCR | 0.0038 | 0.1467 | 0.1467 |
Schistosoma mansoni | opsin-like receptor | 0.0038 | 0.1467 | 0.1467 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0038 | 0.1467 | 0.1635 |
Brugia malayi | Serotonin receptor | 0.0038 | 0.1467 | 0.1635 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0038 | 0.1467 | 0.1467 |
Echinococcus granulosus | serotonin receptor | 0.0038 | 0.1467 | 0.1635 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.7495 | 0.8354 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.1028 | 0.1145 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Brugia malayi | sulfakinin receptor protein | 0.0038 | 0.1467 | 0.1635 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0038 | 0.1467 | 0.1467 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0038 | 0.1467 | 0.1467 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0038 | 0.1467 | 0.1635 |
Onchocerca volvulus | 0.0038 | 0.1467 | 0.5 | |
Onchocerca volvulus | 0.0038 | 0.1467 | 0.5 | |
Loa Loa (eye worm) | TYRA-2 protein | 0.0038 | 0.1467 | 0.1635 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0038 | 0.1467 | 0.1635 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0038 | 0.1467 | 0.1467 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0038 | 0.1467 | 0.1467 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Brugia malayi | RE15519p | 0.0038 | 0.1467 | 0.1635 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0038 | 0.1467 | 0.1467 |
Schistosoma mansoni | histamine h1 receptor | 0.0038 | 0.1467 | 0.1467 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0038 | 0.1467 | 0.1467 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0038 | 0.1467 | 0.1635 |
Brugia malayi | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Schistosoma mansoni | amine GPCR | 0.0038 | 0.1467 | 0.1467 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0038 | 0.1467 | 0.1635 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0038 | 0.1467 | 0.1635 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Echinococcus granulosus | neuropeptide receptor | 0.0038 | 0.1467 | 0.1635 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0116 | 0.8972 | 1 |
Echinococcus granulosus | g protein coupled receptor | 0.0038 | 0.1467 | 0.1635 |
Onchocerca volvulus | 0.0038 | 0.1467 | 0.5 | |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0038 | 0.1467 | 0.5 |
Echinococcus granulosus | voltage gated potassium channel | 0.0033 | 0.1028 | 0.1145 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0038 | 0.1467 | 0.1635 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1467 | 0.1635 |
Schistosoma mansoni | opsin-like receptor | 0.0038 | 0.1467 | 0.1467 |
Onchocerca volvulus | 0.0038 | 0.1467 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
CC50 (ADMET) | = 30 uM | Cytotoxicity against human MT4 cells by MTT assay | ChEMBL. | 21185110 |
IC50 (binding) | Inhibition of recombinant HIV-1 reverse transcriptase RNase H domain after 10 mins | ChEMBL. | 21185110 | |
IC50 (binding) | = 27.8 uM | Inhibition of HIV-1 integrase after 1 hr by immunosorbent assay | ChEMBL. | 21185110 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.