Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Giardia lamblia | Kinase, PLK | 0.0092 | 0.0234 | 1 |
Schistosoma mansoni | regulator of G protein signaling | 0.0018 | 0.0015 | 0.0033 |
Echinococcus granulosus | chromobox protein 1 | 0.0071 | 0.0172 | 0.0378 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.0356 | 0.1016 | 0.7426 |
Entamoeba histolytica | T-complex protein 1 beta subunit, putative | 0.0024 | 0.0035 | 0.0895 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0029 | 0.005 | 0.1842 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0015 | 0.0053 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0066 | 0.0158 | 0.0559 |
Onchocerca volvulus | Segment polarity protein dishevelled homolog | 0.0018 | 0.0015 | 0.0109 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.0234 | 1 |
Brugia malayi | chromobox protein homolog 3 | 0.004 | 0.008 | 0.0284 |
Brugia malayi | T-complex protein 1, beta subunit | 0.0024 | 0.0035 | 0.0123 |
Loa Loa (eye worm) | hypothetical protein | 0.0298 | 0.0845 | 0.2997 |
Brugia malayi | MH2 domain containing protein | 0.0066 | 0.0158 | 0.0559 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.0234 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0021 | 0.0692 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0022 | 0.0027 | 0.0027 |
Leishmania major | GTP-binding protein, putative | 0.0022 | 0.0027 | 0.07 |
Echinococcus multilocularis | Pleckstrin G protein, interacting region | 0.0018 | 0.0015 | 0.0015 |
Brugia malayi | MH2 domain containing protein | 0.0966 | 0.282 | 1 |
Brugia malayi | Pax transcription factor protein 2 | 0.0475 | 0.1368 | 0.4852 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0192 | 0.0531 | 0.0531 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.005 | 0.0178 |
Loa Loa (eye worm) | nuclear factor I | 0.0036 | 0.0071 | 0.0251 |
Loa Loa (eye worm) | hypothetical protein | 0.0204 | 0.0566 | 0.2008 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0021 | 0.0692 |
Trypanosoma brucei | polo-like protein kinase | 0.0092 | 0.0234 | 0.8971 |
Echinococcus multilocularis | Smad4 | 0.0066 | 0.0158 | 0.0158 |
Brugia malayi | Domain found in Dishevelled, Egl-10, and Pleckstrin family protein | 0.0018 | 0.0015 | 0.0053 |
Echinococcus multilocularis | mothers against decapentaplegic 6 | 0.0029 | 0.005 | 0.005 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0092 | 0.0234 | 0.8982 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0022 | 0.0027 | 0.1043 |
Echinococcus granulosus | dna polymerase eta | 0.0019 | 0.0021 | 0.0045 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0018 | 0.0015 | 0.0033 |
Entamoeba histolytica | hypothetical protein | 0.0144 | 0.0389 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0298 | 0.0845 | 0.2997 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0019 | 0.0021 | 0.0878 |
Loa Loa (eye worm) | hypothetical protein | 0.0356 | 0.1016 | 0.3603 |
Schistosoma mansoni | hypothetical protein | 0.0315 | 0.0893 | 0.1961 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.001 | 0.037 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0092 | 0.0234 | 0.8943 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0045 | 0.0097 | 0.4153 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0315 | 0.0893 | 0.3168 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0019 | 0.0021 | 0.0045 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0092 | 0.0234 | 0.083 |
Loa Loa (eye worm) | pax transcription factor protein 2 | 0.0475 | 0.1368 | 0.4852 |
Schistosoma mansoni | hypothetical protein | 0.1553 | 0.4554 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0192 | 0.0531 | 0.1884 |
Brugia malayi | RNA, U transporter 1 | 0.0084 | 0.0211 | 0.0748 |
Brugia malayi | hypothetical protein | 0.0065 | 0.0155 | 0.055 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0101 | 0.0261 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0144 | 0.0389 | 0.0854 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0966 | 0.282 | 1 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0019 | 0.0021 | 0.0878 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0021 | 0.0692 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.0021 | 0.0073 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0021 | 0.0788 |
Brugia malayi | N-terminal motif family protein | 0.0356 | 0.1016 | 0.3603 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.0234 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0144 | 0.0389 | 1 |
Brugia malayi | mothers against decapentaplegic homolog 3 | 0.0029 | 0.005 | 0.0178 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0028 | 0.0046 | 0.1964 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0021 | 0.0692 |
Brugia malayi | Isocitrate dehydrogenase | 0.0016 | 0.001 | 0.0034 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0101 | 0.0261 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0021 | 0.0692 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0092 | 0.0234 | 0.0514 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0092 | 0.0234 | 0.083 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0192 | 0.0531 | 0.1884 |
Brugia malayi | Smad1 | 0.0066 | 0.0158 | 0.0559 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0019 | 0.0021 | 1 |
Brugia malayi | hypothetical protein | 0.0144 | 0.0389 | 0.1379 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0016 | 0.001 | 0.0269 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0022 | 0.0027 | 0.0096 |
Echinococcus multilocularis | GPCR, family 2 | 0.0094 | 0.0242 | 0.0242 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0021 | 0.0692 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0016 | 0.001 | 0.001 |
Onchocerca volvulus | 0.0031 | 0.0055 | 0.0401 | |
Loa Loa (eye worm) | T-complex protein 1 | 0.0024 | 0.0035 | 0.0123 |
Schistosoma mansoni | smad1 5 8 and | 0.0066 | 0.0158 | 0.0346 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0055 | 0.0195 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.001 | 0.001 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0101 | 0.0261 | 1 |
Echinococcus multilocularis | dna polymerase kappa | 0.0019 | 0.0021 | 0.0021 |
Trypanosoma brucei | unspecified product | 0.0019 | 0.0021 | 0.0692 |
Brugia malayi | Importin beta-1 subunit | 0.0029 | 0.005 | 0.0178 |
Echinococcus multilocularis | chromobox protein 1 | 0.0071 | 0.0172 | 0.0172 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0144 | 0.0389 | 0.0854 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0029 | 0.005 | 0.1617 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0022 | 0.0027 | 0.0096 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.0021 | 0.5 |
Brugia malayi | isocitrate dehydrogenase | 0.0016 | 0.001 | 0.0034 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0016 | 0.001 | 0.0021 |
Trichomonas vaginalis | chaperonin, putative | 0.0024 | 0.0035 | 0.1486 |
Echinococcus granulosus | GPCR family 2 | 0.0094 | 0.0242 | 0.0532 |
Schistosoma mansoni | dishevelled | 0.0018 | 0.0015 | 0.0033 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0043 | 0.0089 | 0.0651 |
Onchocerca volvulus | 0.0475 | 0.1368 | 1 | |
Plasmodium vivax | importin-beta 2, putative | 0.0029 | 0.005 | 0.1617 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.001 | 0.001 |
Loa Loa (eye worm) | DIX domain-containing protein | 0.0018 | 0.0015 | 0.0053 |
Echinococcus granulosus | chromobox protein 1 | 0.0071 | 0.0172 | 0.0378 |
Echinococcus multilocularis | chromobox protein 1 | 0.0071 | 0.0172 | 0.0172 |
Echinococcus multilocularis | smad | 0.0066 | 0.0158 | 0.0158 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0066 | 0.0158 | 0.0346 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0066 | 0.0158 | 0.0158 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0028 | 0.0046 | 0.1964 |
Schistosoma mansoni | dishevelled | 0.0018 | 0.0015 | 0.0033 |
Echinococcus granulosus | snurportin 1 | 0.0315 | 0.0893 | 0.1961 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.0018 | 0.0015 | 0.0015 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0298 | 0.0845 | 0.2997 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.0018 | 0.0015 | 0.0033 |
Echinococcus granulosus | Pleckstrin G protein interacting region | 0.0018 | 0.0015 | 0.0033 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0092 | 0.0234 | 0.602 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.0234 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.0234 | 1 |
Trypanosoma brucei | T-complex protein 1, beta subunit, putative | 0.0024 | 0.0035 | 0.1244 |
Toxoplasma gondii | hypothetical protein | 0.0018 | 0.0015 | 0.0209 |
Brugia malayi | hypothetical protein | 0.0101 | 0.0261 | 0.0924 |
Echinococcus granulosus | Smad4 | 0.0066 | 0.0158 | 0.0346 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0066 | 0.0158 | 0.0158 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0092 | 0.0234 | 0.1711 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.0242 | 0.0859 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0016 | 0.001 | 0.037 |
Entamoeba histolytica | hypothetical protein | 0.0024 | 0.0034 | 0.0867 |
Echinococcus multilocularis | geminin | 0.1553 | 0.4554 | 0.4554 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0101 | 0.0261 | 1 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0019 | 0.0021 | 0.0435 |
Trichomonas vaginalis | chromobox protein, putative | 0.0043 | 0.0089 | 0.3804 |
Leishmania major | importin beta-1 subunit, putative | 0.0024 | 0.0034 | 0.096 |
Giardia lamblia | TCP-1 chaperonin subunit beta | 0.0024 | 0.0035 | 0.0667 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0192 | 0.0531 | 0.1166 |
Schistosoma mansoni | smad | 0.0029 | 0.005 | 0.011 |
Schistosoma mansoni | ran | 0.0022 | 0.0027 | 0.006 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0016 | 0.001 | 0.001 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0029 | 0.005 | 0.005 |
Schistosoma mansoni | hypothetical protein | 0.0045 | 0.0097 | 0.0212 |
Schistosoma mansoni | kinase | 0.0047 | 0.0101 | 0.0221 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0144 | 0.0389 | 0.0854 |
Schistosoma mansoni | Smad4 | 0.0029 | 0.005 | 0.011 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0071 | 0.0251 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.0018 | 0.0015 | 0.0015 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0029 | 0.005 | 0.1842 |
Trypanosoma cruzi | T-complex protein 1, beta subunit, putative | 0.0024 | 0.0035 | 0.1335 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0021 | 0.0788 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0018 | 0.0015 | 0.0015 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0094 | 0.0242 | 0.0242 |
Schistosoma mansoni | dep domain containing protein | 0.0018 | 0.0015 | 0.0033 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.0234 | 1 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0019 | 0.0021 | 0.0528 |
Trichomonas vaginalis | chromobox protein, putative | 0.0043 | 0.0089 | 0.3804 |
Schistosoma mansoni | smad1 5 8 and | 0.0066 | 0.0158 | 0.0346 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0022 | 0.0027 | 0.07 |
Trichomonas vaginalis | chromobox protein, putative | 0.0071 | 0.0172 | 0.7346 |
Schistosoma mansoni | fyve finger-containing phosphoinositide kinase fyv1 | 0.0018 | 0.0015 | 0.0033 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.0018 | 0.0015 | 0.0033 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0021 | 0.0692 |
Schistosoma mansoni | hypothetical protein | 0.1553 | 0.4554 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0966 | 0.282 | 1 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0019 | 0.0021 | 0.0788 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0022 | 0.0027 | 0.095 |
Trichomonas vaginalis | importin beta-1, putative | 0.0024 | 0.0034 | 0.1441 |
Trichomonas vaginalis | ran, putative | 0.0022 | 0.0027 | 0.1162 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.0021 | 0.5 |
Plasmodium falciparum | T-complex protein 1 subunit beta | 0.0024 | 0.0035 | 0.1002 |
Echinococcus granulosus | importin subunit beta 1 | 0.0029 | 0.005 | 0.011 |
Loa Loa (eye worm) | G protein signaling regulator EGL-10 | 0.0018 | 0.0015 | 0.0053 |
Echinococcus multilocularis | mothers against decapentaplegic 2 | 0.0029 | 0.005 | 0.005 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0094 | 0.0242 | 0.0859 |
Brugia malayi | MH1 domain containing protein | 0.0066 | 0.0158 | 0.0559 |
Schistosoma mansoni | hypothetical protein | 0.0204 | 0.0566 | 0.1243 |
Brugia malayi | DIX domain containing protein | 0.0018 | 0.0015 | 0.0053 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0045 | 0.0097 | 0.4153 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0045 | 0.0097 | 0.0097 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0018 | 0.0015 | 0.0033 |
Giardia lamblia | GTP-binding nuclear protein RAN/TC4 | 0.0022 | 0.0027 | 0.0312 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0018 | 0.0015 | 0.0015 |
Schistosoma mansoni | Smad4 | 0.0066 | 0.0158 | 0.0346 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0045 | 0.0097 | 0.0212 |
Schistosoma mansoni | DNA polymerase eta | 0.0019 | 0.0021 | 0.0045 |
Onchocerca volvulus | Mothers against decapentaplegic homolog | 0.0029 | 0.005 | 0.0366 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0021 | 0.0788 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0192 | 0.0531 | 0.1166 |
Schistosoma mansoni | hypothetical protein | 0.0094 | 0.0242 | 0.0532 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0029 | 0.005 | 0.0178 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0015 | 0.0053 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.005 | 0.0178 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0094 | 0.0242 | 0.0532 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.001 | 0.0021 |
Entamoeba histolytica | hypothetical protein | 0.0144 | 0.0389 | 1 |
Brugia malayi | hypothetical protein | 0.0018 | 0.0015 | 0.0053 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0094 | 0.0242 | 0.0859 |
Brugia malayi | regulator of G-protein signaling egl-10 | 0.0018 | 0.0015 | 0.0053 |
Schistosoma mansoni | Smad4 | 0.0029 | 0.005 | 0.011 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0019 | 0.0021 | 0.0045 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.004 | 0.008 | 0.0586 |
Brugia malayi | MH2 domain containing protein | 0.0029 | 0.005 | 0.0178 |
Schistosoma mansoni | chromobox protein | 0.0071 | 0.0172 | 0.0378 |
Entamoeba histolytica | Ran family GTPase | 0.0022 | 0.0027 | 0.0699 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0024 | 0.0035 | 0.0076 |
Leishmania major | hypothetical protein, conserved | 0.0101 | 0.0261 | 1 |
Brugia malayi | Domain found in Dishevelled, Egl-10, and Pleckstrin family protein | 0.0018 | 0.0015 | 0.0053 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0019 | 0.0021 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.0234 | 1 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0024 | 0.0035 | 0.0076 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0024 | 0.0034 | 0.1294 |
Schistosoma mansoni | hypothetical protein | 0.0094 | 0.0242 | 0.0532 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0298 | 0.0845 | 0.2997 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0092 | 0.0234 | 0.0234 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0192 | 0.0531 | 0.1166 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0021 | 0.0692 |
Plasmodium falciparum | importin beta, putative | 0.0029 | 0.005 | 0.1617 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0024 | 0.0035 | 0.0076 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.0021 | 0.0021 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0192 | 0.0531 | 0.0531 |
Brugia malayi | Heterochromatin protein 1 | 0.0071 | 0.0172 | 0.061 |
Loa Loa (eye worm) | Smad1 | 0.0066 | 0.0158 | 0.0559 |
Schistosoma mansoni | hypothetical protein | 0.0094 | 0.0242 | 0.0532 |
Schistosoma mansoni | ran | 0.0022 | 0.0027 | 0.006 |
Onchocerca volvulus | 0.0018 | 0.0015 | 0.0109 | |
Echinococcus granulosus | smad | 0.0066 | 0.0158 | 0.0346 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0019 | 0.0021 | 0.0692 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0024 | 0.0034 | 0.1441 |
Echinococcus multilocularis | chaperonin containing TCP1, subunit 2 (beta) | 0.0024 | 0.0035 | 0.0035 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.001 | 0.001 |
Trichomonas vaginalis | chaperonin-60kD, ch60, putative | 0.0024 | 0.0035 | 0.1486 |
Leishmania major | DNA polymerase kappa, putative | 0.0019 | 0.0021 | 0.0435 |
Brugia malayi | MH1 domain containing protein | 0.0066 | 0.0158 | 0.0559 |
Brugia malayi | T-complex protein 1, beta subunit | 0.0024 | 0.0035 | 0.0123 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0066 | 0.0158 | 0.0346 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0029 | 0.005 | 0.0178 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0021 | 0.0788 |
Brugia malayi | MH2 domain containing protein | 0.0066 | 0.0158 | 0.0559 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.0021 | 0.0045 |
Trichomonas vaginalis | chromobox protein, putative | 0.0071 | 0.0172 | 0.7346 |
Leishmania major | DNA polymerase eta, putative | 0.0019 | 0.0021 | 0.0435 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0024 | 0.0034 | 0.1441 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0092 | 0.0234 | 0.8982 |
Plasmodium vivax | T-complex protein 1 subunit beta, putative | 0.0024 | 0.0035 | 0.1002 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0094 | 0.0242 | 0.0242 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.008 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.0261 | 0.0924 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0019 | 0.0021 | 0.0073 |
Entamoeba histolytica | hypothetical protein | 0.0144 | 0.0389 | 1 |
Schistosoma mansoni | importin beta-1 | 0.0029 | 0.005 | 0.011 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 0.008 | 0.3424 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0022 | 0.0027 | 0.07 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0092 | 0.0234 | 0.0514 |
Echinococcus granulosus | geminin | 0.1553 | 0.4554 | 1 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.001 | 0.0269 |
Schistosoma mansoni | z-protein (S1r protein) | 0.0018 | 0.0015 | 0.0033 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0192 | 0.0531 | 0.1166 |
Brugia malayi | MH1 domain containing protein | 0.0036 | 0.0071 | 0.0251 |
Echinococcus multilocularis | dna polymerase eta | 0.0019 | 0.0021 | 0.0021 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0066 | 0.0158 | 0.0346 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0101 | 0.0261 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0021 | 0.0692 |
Brugia malayi | hypothetical protein | 0.0018 | 0.0015 | 0.0053 |
Echinococcus granulosus | chaperonin containing TCP1 subunit 2 beta | 0.0024 | 0.0035 | 0.0076 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0066 | 0.0158 | 0.0559 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0094 | 0.0242 | 0.0859 |
Schistosoma mansoni | smad | 0.0066 | 0.0158 | 0.0346 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0021 | 0.0692 |
Toxoplasma gondii | t-complex protein beta subunit | 0.0024 | 0.0035 | 0.1002 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.0021 | 0.0073 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0144 | 0.0389 | 0.0389 |
Echinococcus granulosus | mothers against decapentaplegic 6 | 0.0029 | 0.005 | 0.011 |
Echinococcus granulosus | dna polymerase kappa | 0.0019 | 0.0021 | 0.0045 |
Leishmania major | T-complex protein 1, beta subunit, putative | 0.0024 | 0.0035 | 0.1002 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0101 | 0.0261 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0015 | 0.0053 |
Echinococcus granulosus | mothers against decapentaplegic 2 | 0.0029 | 0.005 | 0.011 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0204 | 0.0566 | 0.2008 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0021 | 0.0073 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0021 | 0.0692 |
Schistosoma mansoni | chromobox protein | 0.0071 | 0.0172 | 0.0378 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0022 | 0.0027 | 0.006 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0192 | 0.0531 | 0.1166 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0094 | 0.0242 | 0.0532 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0101 | 0.0261 | 1 |
Schistosoma mansoni | smad1 5 8 and | 0.0066 | 0.0158 | 0.0346 |
Brugia malayi | MH1 domain containing protein | 0.0036 | 0.0071 | 0.0251 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0022 | 0.0027 | 0.07 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0071 | 0.0172 | 0.061 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 0.008 | 0.3424 |
Schistosoma mansoni | hypothetical protein | 0.0094 | 0.0242 | 0.0532 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0022 | 0.0027 | 0.1043 |
Echinococcus multilocularis | snurportin 1 | 0.0315 | 0.0893 | 0.0893 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0016 | 0.001 | 0.0034 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0021 | 0.0692 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0021 | 0.0692 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 4.25 | Inhibition of human ERG | ChEMBL. | 21185626 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.