Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.023 | 0.0782 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0074 | 0.2944 | 0.3085 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0074 | 0.2944 | 0.5 |
Brugia malayi | jmjC domain containing protein | 0.0098 | 0.4511 | 1 |
Brugia malayi | jmjC domain containing protein | 0.0036 | 0.0417 | 0.0925 |
Echinococcus granulosus | geminin | 0.0174 | 0.9541 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.1254 | 0.278 |
Echinococcus granulosus | jumonji domain containing protein | 0.0042 | 0.0777 | 0.0814 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0043 | 0.0869 | 0.0911 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0062 | 0.2111 | 0.7171 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0074 | 0.2944 | 0.3085 |
Schistosoma mansoni | hypothetical protein | 0.0174 | 0.9541 | 1 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0074 | 0.2944 | 0.5 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0074 | 0.2944 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0174 | 0.9541 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.023 | 0.0241 |
Schistosoma mansoni | jumonji domain containing protein | 0.0078 | 0.3176 | 0.3329 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0043 | 0.0869 | 0.0911 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.1254 | 0.4261 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0036 | 0.0417 | 0.0437 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.1254 | 0.4261 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0074 | 0.2944 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.1416 | 0.4812 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0036 | 0.0417 | 0.0437 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0074 | 0.2944 | 1 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0074 | 0.2944 | 0.5 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0074 | 0.2944 | 0.6526 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0036 | 0.0417 | 0.1417 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.1254 | 0.278 |
Echinococcus multilocularis | geminin | 0.0174 | 0.9541 | 1 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0098 | 0.4511 | 0.4728 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0036 | 0.0417 | 0.0437 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.023 | 0.051 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0042 | 0.0777 | 0.0814 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0098 | 0.4511 | 0.4728 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0036 | 0.0417 | 0.0437 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0074 | 0.2944 | 0.3085 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.