Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0058 | 0.0079 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0066 | 0.019 |
Echinococcus granulosus | low density lipoprotein receptor ldl | 0.0034 | 0.0058 | 0.0053 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.005 | 0.0111 | 0.0509 |
Loa Loa (eye worm) | hypothetical protein | 0.0312 | 0.103 | 0.141 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0207 | 0.0663 | 0.3141 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0054 | 0.0127 | 0.0127 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0029 | 0.004 | 0.0109 |
Entamoeba histolytica | cysteine protease, putative | 0.0028 | 0.0035 | 0.0669 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0058 | 0.0079 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0058 | 0.0079 |
Onchocerca volvulus | 0.0054 | 0.0127 | 0.0218 | |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0076 | 0.0202 | 0.1844 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0005 | 0.0022 |
Brugia malayi | Pre-SET motif family protein | 0.012 | 0.0356 | 0.0487 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.005 | 0.0111 | 0.0991 |
Echinococcus multilocularis | Smad4 | 0.0143 | 0.0439 | 0.0435 |
Echinococcus granulosus | cysteine protease | 0.0028 | 0.0035 | 0.0031 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0054 | 0.0127 | 0.0378 |
Entamoeba histolytica | cysteine protease, putative | 0.0028 | 0.0035 | 0.0669 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0026 | 0.0028 | 0.0365 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.003 | 0.0041 | 0.0112 |
Schistosoma mansoni | hypothetical protein | 0.0099 | 0.0283 | 0.0283 |
Brugia malayi | Probable ClpP-like protease | 0.0076 | 0.0202 | 0.0277 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0292 | 0.096 | 0.4563 |
Leishmania major | cathepsin L-like protease | 0.0207 | 0.0663 | 0.3141 |
Echinococcus granulosus | Low density lipoprotein receptor class A cysteine rich | 0.0034 | 0.0058 | 0.0053 |
Schistosoma mansoni | hypothetical protein | 0.015 | 0.0462 | 0.0462 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0029 | 0.004 | 0.0109 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0054 | 0.0127 | 0.0378 |
Echinococcus multilocularis | Low density lipoprotein receptor, class A, cysteine rich | 0.0034 | 0.0058 | 0.0053 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0054 | 0.0127 | 0.0378 |
Leishmania major | cysteine peptidase A (CPA) | 0.0054 | 0.0127 | 0.0587 |
Brugia malayi | Pre-SET motif family protein | 0.0834 | 0.2857 | 0.391 |
Echinococcus granulosus | cathepsin l1 | 0.0036 | 0.0065 | 0.006 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.005 | 0.0111 | 0.249 |
Trichomonas vaginalis | set domain proteins, putative | 0.0949 | 0.326 | 1 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0028 | 0.0035 | 0.0146 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0028 | 0.0035 | 0.0048 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.0283 | 0.0387 |
Trypanosoma cruzi | cysteine protease, putative | 0.0028 | 0.0035 | 0.0167 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0036 | 0.0065 | 0.0184 |
Leishmania major | cathepsin L-like protease | 0.0054 | 0.0127 | 0.0587 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0312 | 0.103 | 0.141 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.012 | 0.0356 | 0.0351 |
Schistosoma mansoni | smad | 0.0143 | 0.0439 | 0.0439 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0054 | 0.0127 | 0.0127 |
Echinococcus multilocularis | cysteine protease | 0.0054 | 0.0127 | 0.0123 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0028 | 0.0035 | 0.0048 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0076 | 0.0202 | 0.1844 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor2 | 0.005 | 0.0111 | 0.0529 |
Mycobacterium leprae | PROBABLE BACTERIOFERRITIN BFRA | 0.0044 | 0.0092 | 0.1923 |
Entamoeba histolytica | cysteine protease, putative | 0.0028 | 0.0035 | 0.0669 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0618 | 0.21 | 1 |
Brugia malayi | CUB domain containing protein | 0.0034 | 0.0058 | 0.0079 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.005 | 0.0111 | 0.0991 |
Brugia malayi | basement membrane proteoglycan precursor | 0.0034 | 0.0058 | 0.0079 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0143 | 0.0439 | 0.0435 |
Brugia malayi | Low-density lipoprotein receptor domain class A containing protein | 0.0034 | 0.0058 | 0.0079 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0121 | 0.0359 | 1 |
Echinococcus granulosus | smad | 0.0143 | 0.0439 | 0.0435 |
Giardia lamblia | GTOR | 0.005 | 0.0111 | 1 |
Schistosoma mansoni | Smad4 | 0.0143 | 0.0439 | 0.0439 |
Giardia lamblia | TCP-1 chaperonin subunit beta | 0.0024 | 0.0022 | 0.1618 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0207 | 0.0663 | 0.3141 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0065 | 0.0088 |
Brugia malayi | Cathepsin L-like precursor | 0.0054 | 0.0127 | 0.0174 |
Schistosoma mansoni | ferritin | 0.0044 | 0.0092 | 0.0092 |
Entamoeba histolytica | hypothetical protein | 0.015 | 0.0462 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0054 | 0.0127 | 0.0378 |
Leishmania major | trypanothione reductase | 0.0048 | 0.0104 | 0.0473 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.004 | 0.0075 | 0.0218 |
Loa Loa (eye worm) | Smad1 | 0.0143 | 0.0439 | 0.0601 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.015 | 0.0462 | 0.0458 |
Onchocerca volvulus | Cathepsin F homolog | 0.0054 | 0.0127 | 0.0218 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0189 | 0.06 | 0.2856 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0115 | 0.034 | 0.0336 |
Schistosoma mansoni | hypothetical protein | 0.0214 | 0.0684 | 0.0684 |
Leishmania major | cathepsin L-like protease | 0.0054 | 0.0127 | 0.0587 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.004 | 0.0075 | 0.0218 |
Schistosoma mansoni | apoferritin-2 | 0.0044 | 0.0092 | 0.0092 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0058 | 0.0079 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0042 | 0.0086 | 0.0249 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0058 | 0.0079 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0035 | 0.0048 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0618 | 0.21 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0054 | 0.0127 | 0.0123 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0054 | 0.0127 | 0.0378 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0127 | 0.0174 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0076 | 0.0202 | 0.5398 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0207 | 0.0663 | 0.3141 |
Schistosoma mansoni | smad | 0.0064 | 0.0161 | 0.0161 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0028 | 0.0035 | 0.0031 |
Brugia malayi | Smad1 | 0.0143 | 0.0439 | 0.0601 |
Plasmodium vivax | T-complex protein 1 subunit beta, putative | 0.0024 | 0.0022 | 0.0612 |
Plasmodium vivax | vivapain-2 | 0.0054 | 0.0127 | 0.3583 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0028 | 0.0035 | 0.0669 |
Brugia malayi | Cathepsin L-like precursor | 0.0036 | 0.0065 | 0.0088 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0207 | 0.0663 | 0.3141 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0028 | 0.0035 | 0.0669 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0109 | 0.0317 | 0.2915 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0187 | 0.0593 | 0.0593 |
Loa Loa (eye worm) | low-density lipoprotein receptor domain class A containing protein | 0.0034 | 0.0058 | 0.0079 |
Echinococcus granulosus | tumor protein p63 | 0.1079 | 0.3713 | 0.3711 |
Brugia malayi | Low-density lipoprotein receptor domain class A containing protein | 0.0034 | 0.0058 | 0.0079 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0019 | 0.0005 | 0.0006 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0058 | 0.0079 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0054 | 0.0127 | 0.0123 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0026 | 0.0028 | 0.0797 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0143 | 0.0439 | 0.0601 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.2106 | 0.7307 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.003 | 0.0041 | 0.0112 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0143 | 0.0439 | 0.0435 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 0.0684 | 0.0937 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0618 | 0.21 | 1 |
Echinococcus multilocularis | geminin | 0.035 | 0.1163 | 0.1159 |
Trypanosoma brucei | trypanothione reductase | 0.0048 | 0.0104 | 0.0473 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0019 | 0.0005 | 0.0005 |
Schistosoma mansoni | ferritin | 0.0044 | 0.0092 | 0.0092 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0618 | 0.21 | 1 |
Brugia malayi | Low-density lipoprotein receptor domain class A containing protein | 0.0034 | 0.0058 | 0.0079 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0027 | 0.0031 | 0.0081 |
Entamoeba histolytica | cysteine protease, putative | 0.0028 | 0.0035 | 0.0669 |
Echinococcus granulosus | geminin | 0.035 | 0.1163 | 0.1159 |
Toxoplasma gondii | hypothetical protein | 0.01 | 0.0286 | 0.7905 |
Entamoeba histolytica | hypothetical protein | 0.015 | 0.0462 | 1 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.005 | 0.0111 | 0.0106 |
Loa Loa (eye worm) | low-density lipoprotein receptor domain class A containing protein | 0.0034 | 0.0058 | 0.0079 |
Leishmania major | hypothetical protein, conserved | 0.0028 | 0.0035 | 0.0146 |
Brugia malayi | MH1 domain containing protein | 0.0143 | 0.0439 | 0.0601 |
Schistosoma mansoni | hypothetical protein | 0.035 | 0.1163 | 0.1163 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0024 | 0.0022 | 0.0022 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0064 | 0.0161 | 0.0221 |
Trichomonas vaginalis | chaperonin, putative | 0.0024 | 0.0022 | 0.0053 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.005 | 0.0111 | 0.0107 |
Mycobacterium ulcerans | hypothetical protein | 0.0325 | 0.1076 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0058 | 0.0079 |
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.005 | 0.0111 | 0.0107 |
Plasmodium vivax | vivapain-2 | 0.0054 | 0.0127 | 0.3583 |
Brugia malayi | glutathione reductase | 0.0048 | 0.0104 | 0.0142 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.012 | 0.0356 | 0.0351 |
Schistosoma mansoni | thyroid hormone receptor | 0.0135 | 0.0411 | 0.0411 |
Brugia malayi | MH1 domain containing protein | 0.0143 | 0.0439 | 0.0601 |
Schistosoma mansoni | ferritin | 0.0044 | 0.0092 | 0.0092 |
Plasmodium vivax | SET domain protein, putative | 0.012 | 0.0356 | 1 |
Brugia malayi | Low-density lipoprotein receptor domain class A containing protein | 0.0034 | 0.0058 | 0.0079 |
Mycobacterium ulcerans | bacterioferritin BfrA | 0.0044 | 0.0092 | 0.0816 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0121 | 0.0359 | 0.3311 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0005 | 0.0022 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0076 | 0.0202 | 0.568 |
Plasmodium falciparum | glutathione reductase | 0.0048 | 0.0104 | 0.4537 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0187 | 0.0593 | 0.0589 |
Brugia malayi | MH2 domain containing protein | 0.0064 | 0.0161 | 0.0221 |
Trypanosoma cruzi | T-complex protein 1, beta subunit, putative | 0.0024 | 0.0022 | 0.0104 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0099 | 0.0283 | 0.0279 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0834 | 0.2857 | 0.391 |
Schistosoma mansoni | ferritin light chain | 0.0044 | 0.0092 | 0.0092 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0076 | 0.0202 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0054 | 0.0127 | 0.0378 |
Entamoeba histolytica | cysteine protease, putative | 0.0028 | 0.0035 | 0.0669 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0207 | 0.0663 | 0.3141 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0028 | 0.0035 | 0.0669 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0048 | 0.0104 | 0.0924 |
Brugia malayi | hypothetical protein | 0.0028 | 0.0035 | 0.0048 |
Leishmania major | cathepsin L-like protease | 0.0054 | 0.0127 | 0.0587 |
Plasmodium falciparum | thioredoxin reductase | 0.0048 | 0.0104 | 0.4537 |
Onchocerca volvulus | 0.0054 | 0.0127 | 0.0218 | |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0087 | 0.0241 | 0.1148 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0048 | 0.0104 | 0.0493 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0207 | 0.0663 | 0.3141 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0054 | 0.0127 | 0.0378 |
Entamoeba histolytica | cysteine protease, putative | 0.0028 | 0.0035 | 0.0669 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0143 | 0.0439 | 0.0435 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0024 | 0.0022 | 0.0022 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0036 | 0.0065 | 0.0065 |
Onchocerca volvulus | Cathepsin L homolog | 0.0054 | 0.0127 | 0.0218 |
Entamoeba histolytica | cysteine protease, putative | 0.0028 | 0.0035 | 0.0669 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0087 | 0.0241 | 0.1148 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0058 | 0.0079 |
Loa Loa (eye worm) | glutathione reductase | 0.0048 | 0.0104 | 0.0142 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0033 | 0.0054 | 0.0151 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0099 | 0.0283 | 0.0387 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.012 | 0.0356 | 0.0356 |
Echinococcus multilocularis | mothers against decapentaplegic 6 | 0.0064 | 0.0161 | 0.0157 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0027 | 0.0031 | 0.0081 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0028 | 0.0035 | 0.0035 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0099 | 0.0283 | 0.0387 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.004 | 0.0075 | 0.0218 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0076 | 0.0202 | 0.5 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor1 | 0.005 | 0.0111 | 0.0529 |
Loa Loa (eye worm) | low-density lipoprotein receptor repeat class B containing protein | 0.0034 | 0.0058 | 0.0079 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0109 | 0.0317 | 0.2915 |
Echinococcus multilocularis | cathepsin L | 0.0028 | 0.0035 | 0.0031 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.0005 | 0.0006 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0207 | 0.0663 | 0.3156 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0066 | 0.019 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0036 | 0.0065 | 0.0088 |
Loa Loa (eye worm) | low-density lipoprotein receptor domain class A containing protein | 0.0034 | 0.0058 | 0.0079 |
Brugia malayi | Cathepsin L-like precursor | 0.0036 | 0.0065 | 0.0088 |
Plasmodium vivax | unspecified product | 0.0028 | 0.0035 | 0.0988 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0076 | 0.0202 | 0.0202 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0028 | 0.0035 | 0.0167 |
Echinococcus granulosus | GPCR family 2 | 0.0099 | 0.0283 | 0.0279 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0054 | 0.0127 | 0.0378 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.004 | 0.0075 | 0.0218 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0028 | 0.0035 | 0.0669 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0087 | 0.0241 | 0.1148 |
Toxoplasma gondii | target of rapamycin (TOR), putative | 0.0037 | 0.0066 | 0.1338 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0207 | 0.0663 | 0.3156 |
Trypanosoma cruzi | target of rapamycin kinase 3 | 0.004 | 0.0076 | 0.036 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.0005 | 0.0006 |
Mycobacterium ulcerans | bacterioferritin BfrB | 0.0044 | 0.0092 | 0.0816 |
Loa Loa (eye worm) | T-complex protein 1 | 0.0024 | 0.0022 | 0.003 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0054 | 0.0127 | 0.2685 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0207 | 0.0663 | 0.3141 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0099 | 0.0283 | 0.0387 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0054 | 0.0127 | 0.0123 |
Brugia malayi | MH2 domain containing protein | 0.2106 | 0.7307 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0028 | 0.0035 | 0.0094 |
Brugia malayi | Cathepsin L-like precursor | 0.0054 | 0.0127 | 0.0174 |
Echinococcus granulosus | mothers against decapentaplegic 2 | 0.0064 | 0.0161 | 0.0157 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0066 | 0.019 |
Toxoplasma gondii | hypothetical protein | 0.0026 | 0.0028 | 0.0197 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0027 | 0.0031 | 0.0081 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.012 | 0.0356 | 1 |
Echinococcus multilocularis | basement membrane specific heparan sulfate | 0.0034 | 0.0058 | 0.0053 |
Schistosoma mansoni | low-density lipoprotein receptor (ldl) | 0.0034 | 0.0058 | 0.0058 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0058 | 0.0079 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0028 | 0.0035 | 0.0397 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0048 | 0.0104 | 0.0099 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0143 | 0.0439 | 0.0601 |
Entamoeba histolytica | hypothetical protein | 0.015 | 0.0462 | 1 |
Echinococcus granulosus | peptidase Clp S14 family | 0.005 | 0.0111 | 0.0106 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0207 | 0.0663 | 0.3141 |
Echinococcus granulosus | basement membrane specific heparan sulfate | 0.0034 | 0.0058 | 0.0053 |
Echinococcus multilocularis | chaperonin containing TCP1, subunit 2 (beta) | 0.0024 | 0.0022 | 0.0017 |
Echinococcus granulosus | chaperonin containing TCP1 subunit 2 beta | 0.0024 | 0.0022 | 0.0017 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0121 | 0.0359 | 0.3311 |
Schistosoma mansoni | ferritin light chain | 0.0044 | 0.0092 | 0.0092 |
Brugia malayi | MH2 domain containing protein | 0.0143 | 0.0439 | 0.0601 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0058 | 0.0079 |
Schistosoma mansoni | smad1 5 8 and | 0.0143 | 0.0439 | 0.0439 |
Trypanosoma brucei | target of rapamycin kinase 3, putative | 0.004 | 0.0076 | 0.0339 |
Schistosoma mansoni | Smad4 | 0.0064 | 0.0161 | 0.0161 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0028 | 0.0035 | 0.0167 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0054 | 0.0127 | 0.0378 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.003 | 0.0041 | 0.0112 |
Echinococcus multilocularis | Low density lipoprotein receptor, class A, cysteine rich | 0.0034 | 0.0058 | 0.0053 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0109 | 0.0317 | 0.2915 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0109 | 0.0317 | 0.2915 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0048 | 0.0104 | 0.0142 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.005 | 0.0111 | 0.0111 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.015 | 0.0462 | 0.0462 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.0356 | 0.0487 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.005 | 0.0111 | 0.0327 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0087 | 0.0241 | 0.1129 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0076 | 0.0202 | 0.5 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0312 | 0.103 | 0.141 |
Leishmania major | target of rapamycin (TOR) kinase 2, putative | 0.005 | 0.0111 | 0.0509 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0065 | 0.0088 |
Echinococcus granulosus | low density lipoprotein receptor ldl | 0.0034 | 0.0058 | 0.0053 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.0035 | 0.0735 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0028 | 0.0035 | 0.0146 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0054 | 0.0127 | 0.0378 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0058 | 0.0079 |
Brugia malayi | T-complex protein 1, beta subunit | 0.0024 | 0.0022 | 0.003 |
Leishmania major | cathepsin L-like protease | 0.0054 | 0.0127 | 0.0587 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0054 | 0.0127 | 0.0378 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0054 | 0.0127 | 0.0378 |
Mycobacterium tuberculosis | Probable bacterioferritin BfrA | 0.0044 | 0.0092 | 0.0816 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0054 | 0.0127 | 0.0378 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0036 | 0.0065 | 0.131 |
Brugia malayi | cathepsin L-like precursor | 0.0036 | 0.0065 | 0.0088 |
Brugia malayi | mothers against decapentaplegic homolog 3 | 0.0064 | 0.0161 | 0.0221 |
Echinococcus multilocularis | low density lipoprotein receptor protein | 0.0034 | 0.0058 | 0.0053 |
Onchocerca volvulus | Cathepsin L homolog | 0.0054 | 0.0127 | 0.0218 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0027 | 0.0031 | 0.0081 |
Trypanosoma brucei | FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative | 0.0021 | 0.0009 | 0.0023 |
Echinococcus multilocularis | tumor protein p63 | 0.1079 | 0.3713 | 0.3711 |
Onchocerca volvulus | 0.0949 | 0.326 | 1 | |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0028 | 0.0035 | 0.0035 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0054 | 0.0127 | 0.0378 |
Schistosoma mansoni | hypothetical protein | 0.0099 | 0.0283 | 0.0283 |
Onchocerca volvulus | 0.012 | 0.0356 | 0.0931 | |
Schistosoma mansoni | low-density lipoprotein receptor (ldl) | 0.0034 | 0.0058 | 0.0058 |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.005 | 0.0111 | 0.0509 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0058 | 0.0079 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0028 | 0.0035 | 0.0742 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0135 | 0.0411 | 0.0407 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0027 | 0.0031 | 0.0081 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.005 | 0.0111 | 0.0152 |
Brugia malayi | hypothetical protein | 0.015 | 0.0462 | 0.0633 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.004 | 0.0075 | 0.0218 |
Onchocerca volvulus | 0.0054 | 0.0127 | 0.0218 | |
Toxoplasma gondii | cathepsin CPL | 0.0054 | 0.0127 | 0.3165 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0034 | 0.0058 | 0.0058 |
Leishmania major | target of rapamycin (TOR) kinase 1, putative | 0.005 | 0.0111 | 0.0509 |
Echinococcus multilocularis | ferritin | 0.0044 | 0.0092 | 0.0088 |
Brugia malayi | Cathepsin L-like precursor | 0.0054 | 0.0127 | 0.0174 |
Echinococcus granulosus | Smad4 | 0.0143 | 0.0439 | 0.0435 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0076 | 0.0202 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0064 | 0.0161 | 0.0221 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0058 | 0.0079 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0058 | 0.0079 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0214 | 0.0684 | 0.0937 |
Plasmodium vivax | vivapain-3 | 0.0028 | 0.0035 | 0.0988 |
Onchocerca volvulus | Mothers against decapentaplegic homolog | 0.0064 | 0.0161 | 0.0324 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.0035 | 0.0735 |
Echinococcus multilocularis | Low density lipoprotein receptor, class A, cysteine rich | 0.0034 | 0.0058 | 0.0053 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0028 | 0.0035 | 0.0167 |
Brugia malayi | Cathepsin L-like precursor | 0.0054 | 0.0127 | 0.0174 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0076 | 0.0202 | 0.0198 |
Echinococcus granulosus | cathepsin l1 | 0.0054 | 0.0127 | 0.0123 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0028 | 0.0035 | 0.0146 |
Schistosoma mansoni | smad1 5 8 and | 0.0143 | 0.0439 | 0.0439 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0187 | 0.0593 | 0.0589 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0325 | 0.1076 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0143 | 0.0439 | 0.0601 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0054 | 0.0127 | 0.2685 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0187 | 0.0593 | 0.0593 |
Brugia malayi | Low-density lipoprotein receptor-related protein, putative | 0.0034 | 0.0058 | 0.0079 |
Loa Loa (eye worm) | ctsf protein | 0.0054 | 0.0127 | 0.0174 |
Echinococcus granulosus | mothers against decapentaplegic 6 | 0.0064 | 0.0161 | 0.0157 |
Onchocerca volvulus | 0.0054 | 0.0127 | 0.0218 | |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.005 | 0.0111 | 0.0327 |
Trypanosoma brucei | T-complex protein 1, beta subunit, putative | 0.0024 | 0.0022 | 0.0082 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0054 | 0.0127 | 0.5863 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0076 | 0.0202 | 0.0198 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0076 | 0.0202 | 0.5398 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0143 | 0.0439 | 0.0439 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0024 | 0.0022 | 0.0022 |
Schistosoma mansoni | hypothetical protein | 0.0099 | 0.0283 | 0.0283 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0187 | 0.0593 | 0.0812 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0076 | 0.0202 | 0.5249 |
Entamoeba histolytica | cysteine protease, putative | 0.0028 | 0.0035 | 0.0669 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0066 | 0.019 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0005 | 0.0022 |
Brugia malayi | Low-density lipoprotein receptor domain class A containing protein | 0.0034 | 0.0058 | 0.0079 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0187 | 0.0593 | 0.0589 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.005 | 0.0111 | 0.0327 |
Plasmodium vivax | glutathione reductase, putative | 0.0048 | 0.0104 | 0.2911 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0207 | 0.0663 | 0.3141 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0048 | 0.0104 | 0.0099 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0032 | 0.005 | 0.014 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0005 | 0.0022 |
Entamoeba histolytica | phosphatidylinositol3-kinaseTor2, putative | 0.005 | 0.0111 | 0.2327 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0028 | 0.0035 | 0.0167 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0027 | 0.0031 | 0.0081 |
Leishmania major | cathepsin L-like protease | 0.0207 | 0.0663 | 0.3141 |
Onchocerca volvulus | 0.0158 | 0.049 | 0.1349 | |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0028 | 0.0035 | 0.0035 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0076 | 0.0202 | 1 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0109 | 0.0317 | 0.8719 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0106 | 0.0308 | 0.1465 |
Echinococcus granulosus | 5'partial|Low density lipoprotein receptor class A cysteine rich | 0.0034 | 0.0058 | 0.0053 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0202 | 0.0277 |
Brugia malayi | Cathepsin L-like precursor | 0.0054 | 0.0127 | 0.0174 |
Entamoeba histolytica | cysteine protease, putative | 0.0028 | 0.0035 | 0.0669 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0054 | 0.0127 | 0.0123 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0207 | 0.0663 | 0.3141 |
Brugia malayi | MH1 domain containing protein | 0.0079 | 0.0215 | 0.0294 |
Echinococcus multilocularis | GPCR, family 2 | 0.0099 | 0.0283 | 0.0279 |
Brugia malayi | T-complex protein 1, beta subunit | 0.0024 | 0.0022 | 0.003 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0207 | 0.0663 | 0.3141 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0054 | 0.0127 | 0.5863 |
Entamoeba histolytica | cysteine protease, putative | 0.0028 | 0.0035 | 0.0669 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0027 | 0.0031 | 0.0081 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.2106 | 0.7307 | 1 |
Echinococcus multilocularis | smad | 0.0143 | 0.0439 | 0.0435 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0099 | 0.0283 | 0.0279 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0054 | 0.0127 | 0.0123 |
Loa Loa (eye worm) | fibroinase | 0.0054 | 0.0127 | 0.0174 |
Entamoeba histolytica | cysteine protease, putative | 0.0028 | 0.0035 | 0.0669 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.015 | 0.0462 | 0.0458 |
Schistosoma mansoni | low-density lipoprotein receptor (ldl) | 0.0034 | 0.0058 | 0.0058 |
Entamoeba histolytica | hypothetical protein | 0.015 | 0.0462 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0135 | 0.0411 | 0.0411 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0028 | 0.0035 | 0.0985 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0054 | 0.0127 | 0.0378 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0066 | 0.019 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0054 | 0.0127 | 0.0174 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.012 | 0.0356 | 0.0356 |
Entamoeba histolytica | cysteine protease, putative | 0.0028 | 0.0035 | 0.0669 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0019 | 0.0005 | 0.0022 |
Trichomonas vaginalis | chaperonin-60kD, ch60, putative | 0.0024 | 0.0022 | 0.0053 |
Entamoeba histolytica | cysteine protease, putative | 0.0054 | 0.0127 | 0.2685 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0058 | 0.0058 |
Trypanosoma brucei | phosphatidylinositol 3-kinase tor, putative | 0.0024 | 0.0019 | 0.0071 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.012 | 0.0356 | 0.0356 |
Loa Loa (eye worm) | nuclear factor I | 0.0079 | 0.0215 | 0.0294 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0054 | 0.0127 | 0.0174 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0028 | 0.0035 | 0.0669 |
Echinococcus multilocularis | basement membrane specific heparan sulfate | 0.0034 | 0.0058 | 0.0053 |
Leishmania major | T-complex protein 1, beta subunit, putative | 0.0024 | 0.0022 | 0.0082 |
Echinococcus granulosus | cathepsin L | 0.0028 | 0.0035 | 0.0031 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0054 | 0.0127 | 0.0378 |
Mycobacterium tuberculosis | Probable reductase | 0.0109 | 0.0317 | 0.2915 |
Echinococcus multilocularis | mothers against decapentaplegic 2 | 0.0064 | 0.0161 | 0.0157 |
Schistosoma mansoni | Smad4 | 0.0064 | 0.0161 | 0.0161 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0054 | 0.0127 | 0.0378 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0054 | 0.0127 | 0.0378 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0054 | 0.0127 | 0.0123 |
Echinococcus granulosus | ferritin | 0.0044 | 0.0092 | 0.0088 |
Brugia malayi | Low-density lipoprotein receptor domain class A containing protein | 0.0034 | 0.0058 | 0.0079 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0187 | 0.0593 | 0.0589 |
Schistosoma mansoni | ferritin | 0.0044 | 0.0092 | 0.0092 |
Echinococcus multilocularis | expressed protein | 0.0044 | 0.0092 | 0.0088 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0125 | 0.0376 | 0.0372 |
Brugia malayi | Cathepsin L-like precursor | 0.0054 | 0.0127 | 0.0174 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0054 | 0.0127 | 0.0378 |
Leishmania major | cathepsin L-like protease | 0.0054 | 0.0127 | 0.0587 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0066 | 0.019 |
Treponema pallidum | bacterioferrin (TpF1) | 0.0044 | 0.0092 | 0.3664 |
Mycobacterium tuberculosis | Bacterioferritin BfrB | 0.0044 | 0.0092 | 0.0816 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0207 | 0.0663 | 0.3156 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.012 | 0.0356 | 0.0351 |
Schistosoma mansoni | smad1 5 8 and | 0.0143 | 0.0439 | 0.0439 |
Entamoeba histolytica | cysteine proteinase 2 | 0.0028 | 0.0035 | 0.0669 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0158 | 0.049 | 0.049 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0034 | 0.0058 | 0.0079 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0109 | 0.0317 | 0.2915 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0099 | 0.0283 | 0.0279 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0054 | 0.0127 | 0.0378 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0099 | 0.0283 | 0.0279 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0143 | 0.0439 | 0.0435 |
Entamoeba histolytica | cysteine protease, putative | 0.0028 | 0.0035 | 0.0669 |
Onchocerca volvulus | 0.0054 | 0.0127 | 0.0218 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0054 | 0.0127 | 0.0378 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0048 | 0.0104 | 0.2911 |
Echinococcus multilocularis | low density lipoprotein receptor (ldl) | 0.0034 | 0.0058 | 0.0053 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0054 | 0.0127 | 0.0123 |
Echinococcus granulosus | low density lipoprotein receptor protein | 0.0034 | 0.0058 | 0.0053 |
Schistosoma mansoni | hypothetical protein | 0.035 | 0.1163 | 0.1163 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0054 | 0.0127 | 0.0174 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0125 | 0.0376 | 0.0372 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0028 | 0.0035 | 0.0167 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0292 | 0.096 | 0.4575 |
Onchocerca volvulus | 0.0054 | 0.0127 | 0.0218 | |
Onchocerca volvulus | 0.0036 | 0.0065 | 0.0021 | |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0187 | 0.0593 | 0.0812 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0163 | 0.0507 | 0.2417 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0058 | 0.0058 |
Schistosoma mansoni | apoferritin-2 | 0.0044 | 0.0092 | 0.0092 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0312 | 0.103 | 0.141 |
Brugia malayi | MH1 domain containing protein | 0.0079 | 0.0215 | 0.0294 |
Brugia malayi | enteropeptidase precursor | 0.0034 | 0.0058 | 0.0079 |
Trichomonas vaginalis | ferritin, putative | 0.0044 | 0.0092 | 0.0269 |
Loa Loa (eye worm) | calcium binding EGF domain-containing protein | 0.0034 | 0.0058 | 0.0079 |
Brugia malayi | Low-density lipoprotein receptor domain class A containing protein | 0.0034 | 0.0058 | 0.0079 |
Loa Loa (eye worm) | cysteine protease | 0.0054 | 0.0127 | 0.0174 |
Leishmania major | cathepsin L-like protease | 0.0207 | 0.0663 | 0.3141 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0054 | 0.0127 | 0.5863 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0215 | 0.0294 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0054 | 0.0127 | 0.0378 |
Brugia malayi | Low-density lipoprotein receptor repeat class B containing protein | 0.0034 | 0.0058 | 0.0079 |
Entamoeba histolytica | FKBP-rapamycin associated protein (FRAP), putative | 0.005 | 0.0111 | 0.2327 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0187 | 0.0593 | 0.0593 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0161 | 0.0221 |
Loa Loa (eye worm) | hypothetical protein | 0.0158 | 0.049 | 0.067 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.012 | 0.0356 | 0.0356 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0028 | 0.0035 | 0.0167 |
Echinococcus granulosus | basement membrane specific heparan sulfate | 0.0034 | 0.0058 | 0.0053 |
Schistosoma mansoni | hypothetical protein | 0.0125 | 0.0376 | 0.0376 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0054 | 0.0127 | 0.0378 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0019 | 0.0005 | 0.0005 |
Onchocerca volvulus | 0.0054 | 0.0127 | 0.0218 | |
Entamoeba histolytica | T-complex protein 1 beta subunit, putative | 0.0024 | 0.0022 | 0.0377 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0054 | 0.0127 | 0.0378 |
Toxoplasma gondii | thioredoxin reductase | 0.0048 | 0.0104 | 0.2449 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0005 | 0.0006 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0036 | 0.0065 | 0.0184 |
Leishmania major | target of rapamycin kinase (TOR) kinase 3 | 0.004 | 0.0076 | 0.0339 |
Echinococcus multilocularis | low density lipoprotein receptor (ldl) | 0.0034 | 0.0058 | 0.0053 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0054 | 0.0127 | 0.0607 |
Schistosoma mansoni | DNA polymerase eta | 0.0019 | 0.0005 | 0.0005 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0121 | 0.0359 | 0.3311 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0207 | 0.0663 | 0.3156 |
Echinococcus granulosus | expressed protein | 0.0044 | 0.0092 | 0.0088 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0028 | 0.0035 | 0.0094 |
Plasmodium vivax | vivapain-1 | 0.0028 | 0.0035 | 0.0988 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0292 | 0.096 | 0.4563 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0066 | 0.019 |
Schistosoma mansoni | hypothetical protein | 0.0099 | 0.0283 | 0.0283 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.005 | 0.0111 | 0.0152 |
Brugia malayi | Thioredoxin reductase | 0.0048 | 0.0104 | 0.0142 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0065 | 0.0088 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0054 | 0.0127 | 0.0378 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | = 91 uM | Antiplasmodial activity against chloroquine-resistant Plasmodium falciparum W2 by parasite lactate dehydrogenase assay | ChEMBL. | 21396749 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.