Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Treponema pallidum | recombinase A | 0.0104 | 0.0354 | 0.5 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0091 | 0.0276 | 0.5 |
Mycobacterium ulcerans | recombinase A | 0.0104 | 0.0354 | 0.5 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0158 | 0.0672 | 1 |
Chlamydia trachomatis | recombinase RecA | 0.0104 | 0.0354 | 0.5 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0091 | 0.0276 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0091 | 0.0276 | 1 |
Giardia lamblia | Kinase, PLK | 0.0091 | 0.0276 | 0.5 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0091 | 0.0276 | 1 |
Trypanosoma brucei | polo-like protein kinase | 0.0091 | 0.0276 | 0.5 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0158 | 0.0672 | 1 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0091 | 0.0276 | 0.5 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0091 | 0.0276 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0091 | 0.0276 | 1 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0158 | 0.0672 | 1 |
Schistosoma mansoni | alpha-glucosidase | 0.0136 | 0.0541 | 1 |
Schistosoma mansoni | alpha-glucosidase | 0.0136 | 0.0541 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0158 | 0.0672 | 1 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0612 | 0.339 | 1 |
Wolbachia endosymbiont of Brugia malayi | recombinase A | 0.0104 | 0.0354 | 0.5 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0091 | 0.0276 | 0.5 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0091 | 0.0276 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0091 | 0.0276 | 1 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0158 | 0.0672 | 1 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0091 | 0.0276 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0091 | 0.0276 | 0.5037 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0091 | 0.0276 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.