Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0086 | 0.7348 | 0.8205 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0096 | 0.8423 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0086 | 0.7348 | 0.8632 |
Brugia malayi | Cathepsin L-like precursor | 0.0086 | 0.7348 | 0.7348 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0086 | 0.7348 | 0.8205 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0096 | 0.8423 | 1 |
Echinococcus multilocularis | L aminoadipate semialdehyde | 0.0084 | 0.7079 | 0.8405 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.0029 | 0.0562 | 0.0562 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0058 | 0.3996 | 0.3996 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0086 | 0.7348 | 0.8205 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0045 | 0.2432 | 0.2432 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0086 | 0.7348 | 0.7348 |
Onchocerca volvulus | 0.0058 | 0.3996 | 0.3996 | |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0061 | 0.4418 | 0.4418 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0045 | 0.2432 | 0.238 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0086 | 0.7348 | 0.8205 |
Toxoplasma gondii | cathepsin CPL | 0.0086 | 0.7348 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0086 | 0.7348 | 0.8205 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0086 | 0.7348 | 0.8205 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0086 | 0.7348 | 0.8205 |
Plasmodium vivax | vivapain-2 | 0.0086 | 0.7348 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0096 | 0.8423 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0086 | 0.7348 | 0.7348 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0096 | 0.8423 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0047 | 0.2761 | 0.0548 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0045 | 0.2432 | 0.238 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0096 | 0.8423 | 0.8423 |
Brugia malayi | Cathepsin L-like precursor | 0.0029 | 0.0562 | 0.0562 |
Plasmodium vivax | unspecified product | 0.0045 | 0.2432 | 0.2757 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0086 | 0.7348 | 0.8205 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0086 | 0.7348 | 0.8205 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0086 | 0.7348 | 0.8723 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0086 | 0.7348 | 0.8205 |
Echinococcus multilocularis | cathepsin L | 0.0045 | 0.2432 | 0.2888 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0058 | 0.3996 | 0.4369 |
Leishmania major | cathepsin L-like protease | 0.0086 | 0.7348 | 0.7315 |
Onchocerca volvulus | Cathepsin L homolog | 0.0086 | 0.7348 | 0.7348 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0086 | 0.7348 | 0.7348 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0086 | 0.7348 | 0.8205 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0058 | 0.3996 | 0.2611 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0086 | 0.7348 | 0.8723 |
Loa Loa (eye worm) | ctsf protein | 0.0086 | 0.7348 | 0.7348 |
Onchocerca volvulus | 0.0086 | 0.7348 | 0.7348 | |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.7079 | 0.7079 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0086 | 0.7348 | 0.8205 |
Trypanosoma brucei | polo-like protein kinase | 0.0096 | 0.8423 | 1 |
Onchocerca volvulus | 0.0086 | 0.7348 | 0.7348 | |
Echinococcus multilocularis | cysteine protease | 0.0086 | 0.7348 | 0.8723 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0086 | 0.7348 | 0.8205 |
Brugia malayi | cathepsin L-like precursor | 0.0058 | 0.3996 | 0.3996 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0096 | 0.8423 | 0.8423 |
Plasmodium vivax | vivapain-2 | 0.0086 | 0.7348 | 1 |
Echinococcus granulosus | L aminoadipate semialdehyde | 0.0084 | 0.7079 | 0.8405 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.4418 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0086 | 0.7348 | 0.8205 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0086 | 0.7348 | 0.8205 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0562 | 0.0562 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0086 | 0.7348 | 0.8205 |
Leishmania major | cathepsin L-like protease | 0.0086 | 0.7348 | 0.7315 |
Brugia malayi | Cathepsin L-like precursor | 0.0086 | 0.7348 | 0.7348 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.4418 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0086 | 0.7348 | 0.8205 |
Echinococcus granulosus | cathepsin l1 | 0.0086 | 0.7348 | 0.8723 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0086 | 0.7348 | 0.8632 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0086 | 0.7348 | 0.8205 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0086 | 0.7348 | 0.8723 |
Onchocerca volvulus | 0.0086 | 0.7348 | 0.7348 | |
Trichomonas vaginalis | CAMK family protein kinase | 0.0096 | 0.8423 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0045 | 0.2432 | 0.238 |
Brugia malayi | Cathepsin L-like precursor | 0.0086 | 0.7348 | 0.7348 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0086 | 0.7348 | 0.8205 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0086 | 0.7348 | 0.7348 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0045 | 0.2432 | 0.238 |
Schistosoma mansoni | kinase | 0.0049 | 0.2909 | 0.2909 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0096 | 0.8423 | 1 |
Trypanosoma cruzi | cysteine protease, putative | 0.0045 | 0.2432 | 0.238 |
Onchocerca volvulus | 0.0086 | 0.7348 | 0.7348 | |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0096 | 0.8423 | 0.8423 |
Leishmania major | cathepsin L-like protease | 0.0086 | 0.7348 | 0.7315 |
Leishmania major | cathepsin L-like protease | 0.0086 | 0.7348 | 0.7315 |
Brugia malayi | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase | 0.0084 | 0.7079 | 0.7079 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0058 | 0.3996 | 0.2611 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0086 | 0.7348 | 0.8632 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0086 | 0.7348 | 1 |
Onchocerca volvulus | 0.0086 | 0.7348 | 0.7348 | |
Loa Loa (eye worm) | fibroinase | 0.0086 | 0.7348 | 0.7348 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0045 | 0.2432 | 0.2432 |
Brugia malayi | Cathepsin L-like precursor | 0.0086 | 0.7348 | 0.7348 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0086 | 0.7348 | 0.8205 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0086 | 0.7348 | 0.8723 |
Leishmania major | cathepsin L-like protease | 0.0086 | 0.7348 | 0.7315 |
Onchocerca volvulus | 0.0086 | 0.7348 | 0.7348 | |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0045 | 0.2432 | 0.2432 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.3996 | 0.3996 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0029 | 0.0562 | 0.0562 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0086 | 0.7348 | 0.8205 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.3996 | 0.3996 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0086 | 0.7348 | 0.8205 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0086 | 0.7348 | 0.8205 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.3996 | 0.3996 |
Echinococcus multilocularis | cysteine protease | 0.0086 | 0.7348 | 0.8723 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0086 | 0.7348 | 0.8205 |
Plasmodium vivax | vivapain-1 | 0.0045 | 0.2432 | 0.2757 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.4418 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0086 | 0.7348 | 0.8205 |
Giardia lamblia | Kinase, PLK | 0.0096 | 0.8423 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0086 | 0.7348 | 0.8205 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0086 | 0.7348 | 0.8205 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0086 | 0.7348 | 1 |
Schistosoma mansoni | aminoadipate-semialdehyde dehydrogenase | 0.0084 | 0.7079 | 0.7079 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0096 | 0.8423 | 0.8423 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0086 | 0.7348 | 0.8205 |
Leishmania major | cysteine peptidase A (CPA) | 0.0086 | 0.7348 | 0.7315 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0045 | 0.2432 | 0.2888 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0086 | 0.7348 | 0.8723 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0086 | 0.7348 | 0.8205 |
Leishmania major | cathepsin L-like protease | 0.0086 | 0.7348 | 0.7315 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0086 | 0.7348 | 0.8205 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0096 | 0.8423 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0086 | 0.7348 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0058 | 0.3996 | 0.3996 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0058 | 0.3996 | 0.3996 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0086 | 0.7348 | 0.8723 |
Leishmania major | cathepsin L-like protease | 0.0086 | 0.7348 | 0.7315 |
Onchocerca volvulus | 0.0085 | 0.7211 | 0.7211 | |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0061 | 0.4418 | 0.5245 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0086 | 0.7348 | 0.8205 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0096 | 0.8423 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0086 | 0.7348 | 0.8205 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0096 | 0.8423 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0061 | 0.4418 | 0.4418 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0086 | 0.7348 | 0.8205 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0029 | 0.0562 | 0.0562 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0086 | 0.7348 | 0.7348 |
Brugia malayi | Cathepsin L-like precursor | 0.0058 | 0.3996 | 0.3996 |
Entamoeba histolytica | cysteine protease, putative | 0.0086 | 0.7348 | 0.8205 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0086 | 0.7348 | 0.8205 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0045 | 0.2432 | 0.2432 |
Brugia malayi | Cathepsin L-like precursor | 0.0086 | 0.7348 | 0.7348 |
Schistosoma mansoni | cathepsin s | 0.0029 | 0.0562 | 0.0562 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0086 | 0.7348 | 0.8632 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0061 | 0.4418 | 0.5245 |
Onchocerca volvulus | 0.0086 | 0.7348 | 0.7348 | |
Onchocerca volvulus | 0.0084 | 0.7079 | 0.7079 | |
Trichomonas vaginalis | CAMK family protein kinase | 0.0096 | 0.8423 | 1 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0061 | 0.4418 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0058 | 0.3996 | 0.2611 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0086 | 0.7348 | 0.8205 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.7348 | 0.7348 |
Onchocerca volvulus | Cathepsin L homolog | 0.0086 | 0.7348 | 0.7348 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0562 | 0.0562 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0096 | 0.8423 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0047 | 0.2761 | 0.0548 |
Echinococcus granulosus | cathepsin l1 | 0.0058 | 0.3996 | 0.4745 |
Echinococcus granulosus | cathepsin L | 0.0045 | 0.2432 | 0.2888 |
Brugia malayi | Cathepsin L-like precursor | 0.0086 | 0.7348 | 0.7348 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0086 | 0.7348 | 0.8205 |
Echinococcus granulosus | cysteine protease | 0.0045 | 0.2432 | 0.2888 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0562 | 0.0562 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0096 | 0.8423 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0045 | 0.2432 | 0.2432 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0086 | 0.7348 | 0.8632 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0086 | 0.7348 | 0.8205 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0086 | 0.7348 | 0.8205 |
Leishmania major | cathepsin L-like protease | 0.0086 | 0.7348 | 0.7315 |
Loa Loa (eye worm) | cysteine protease | 0.0086 | 0.7348 | 0.7348 |
Plasmodium vivax | vivapain-3 | 0.0045 | 0.2432 | 0.2757 |
Onchocerca volvulus | Cathepsin F homolog | 0.0086 | 0.7348 | 0.7348 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0096 | 0.8423 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.