Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | cathepsin CPL | 0.009 | 0.6495 | 0.5 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.006 | 0.2067 | 0.2067 |
Onchocerca volvulus | 0.009 | 0.6495 | 0.5582 | |
Onchocerca volvulus | Cathepsin F homolog | 0.009 | 0.6495 | 0.5582 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.009 | 0.6495 | 1 |
Leishmania major | cathepsin L-like protease | 0.009 | 0.6495 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.009 | 0.6495 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.009 | 0.6495 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.009 | 0.6495 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.009 | 0.6495 | 1 |
Leishmania major | cathepsin L-like protease | 0.009 | 0.6495 | 0.5 |
Onchocerca volvulus | 0.009 | 0.6495 | 0.5582 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.009 | 0.6495 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.009 | 0.6495 | 0.6495 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.009 | 0.6495 | 1 |
Echinococcus multilocularis | cysteine protease | 0.009 | 0.6495 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.009 | 0.6495 | 0.5582 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.009 | 0.6495 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.009 | 0.6495 | 1 |
Leishmania major | cathepsin L-like protease | 0.009 | 0.6495 | 0.5 |
Leishmania major | cathepsin L-like protease | 0.009 | 0.6495 | 0.5 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.009 | 0.6495 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.009 | 0.6495 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.006 | 0.2067 | 0.2067 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.009 | 0.6495 | 1 |
Plasmodium vivax | vivapain-2 | 0.009 | 0.6495 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.009 | 0.6495 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.009 | 0.6495 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.006 | 0.2067 | 0.2067 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.009 | 0.6495 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.009 | 0.6495 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.006 | 0.2067 | 0.3182 |
Onchocerca volvulus | 0.0089 | 0.6314 | 0.5354 | |
Entamoeba histolytica | cysteine proteinase, putative | 0.009 | 0.6495 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.009 | 0.6495 | 1 |
Loa Loa (eye worm) | fibroinase | 0.009 | 0.6495 | 0.5582 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.009 | 0.6495 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.009 | 0.6495 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.009 | 0.6495 | 0.6495 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.009 | 0.6495 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.006 | 0.2067 | 0.2067 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.009 | 0.6495 | 1 |
Onchocerca volvulus | 0.009 | 0.6495 | 0.5582 | |
Entamoeba histolytica | cysteine protease, putative | 0.009 | 0.6495 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.006 | 0.2067 | 0.2067 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.009 | 0.6495 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.009 | 0.6495 | 1 |
Echinococcus multilocularis | cysteine protease | 0.009 | 0.6495 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.006 | 0.2067 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.009 | 0.6495 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.009 | 0.6495 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.009 | 0.6495 | 1 |
Leishmania major | cathepsin L-like protease | 0.009 | 0.6495 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.009 | 0.6495 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.006 | 0.2067 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.009 | 0.6495 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.009 | 0.6495 | 0.6495 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.009 | 0.6495 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.009 | 0.6495 | 0.6495 |
Leishmania major | cathepsin L-like protease | 0.009 | 0.6495 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.009 | 0.6495 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.009 | 0.6495 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.009 | 0.6495 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.009 | 0.6495 | 0.5582 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.009 | 0.6495 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.009 | 0.6495 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.009 | 0.6495 | 0.6495 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.009 | 0.6495 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.009 | 0.6495 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.009 | 0.6495 | 0.6495 |
Leishmania major | cysteine peptidase A (CPA) | 0.009 | 0.6495 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.009 | 0.6495 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.009 | 0.6495 | 1 |
Leishmania major | cathepsin L-like protease | 0.009 | 0.6495 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.006 | 0.2067 | 0.3182 |
Brugia malayi | Cathepsin L-like precursor | 0.009 | 0.6495 | 0.6495 |
Leishmania major | cathepsin L-like protease | 0.009 | 0.6495 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.009 | 0.6495 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.009 | 0.6495 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.009 | 0.6495 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.009 | 0.6495 | 0.5582 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.009 | 0.6495 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.009 | 0.6495 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.009 | 0.6495 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.006 | 0.2067 | 0.3182 |
Loa Loa (eye worm) | cysteine protease | 0.009 | 0.6495 | 0.5582 |
Onchocerca volvulus | Cathepsin L homolog | 0.009 | 0.6495 | 0.5582 |
Onchocerca volvulus | Cathepsin L homolog | 0.009 | 0.6495 | 0.5582 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.009 | 0.6495 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.009 | 0.6495 | 0.6495 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.6495 | 0.5582 |
Plasmodium vivax | vivapain-2 | 0.009 | 0.6495 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.009 | 0.6495 | 1 |
Onchocerca volvulus | 0.009 | 0.6495 | 0.5582 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.009 | 0.6495 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.009 | 0.6495 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.009 | 0.6495 | 0.6495 |
Onchocerca volvulus | 0.009 | 0.6495 | 0.5582 | |
Onchocerca volvulus | 0.009 | 0.6495 | 0.5582 | |
Onchocerca volvulus | 0.009 | 0.6495 | 0.5582 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.009 | 0.6495 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.009 | 0.6495 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.009 | 0.6495 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.009 | 0.6495 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.