Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0026 | 0.3709 | 0.5 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0026 | 0.3709 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.4456 | 0.4026 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0028 | 0.4456 | 0.5 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0026 | 0.3709 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.3709 | 0.3709 |
Mycobacterium ulcerans | hypothetical protein | 0.0026 | 0.3709 | 1 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0026 | 0.3709 | 0.5 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0026 | 0.3709 | 1 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0026 | 0.3709 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.4456 | 1 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0026 | 0.3709 | 0.5 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.3709 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3709 | 0.3221 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.3709 | 0.3709 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3709 | 0.3221 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0026 | 0.3709 | 0.5 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.3709 | 0.3709 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.3709 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0028 | 0.4456 | 1 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0019 | 0.0719 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3709 | 0.3221 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0028 | 0.4456 | 0.5 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.3709 | 1 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0026 | 0.3709 | 1 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0028 | 0.4456 | 0.5 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0026 | 0.3709 | 1 |
Brugia malayi | hypothetical protein | 0.0028 | 0.4456 | 0.4456 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0028 | 0.4456 | 0.5 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.4456 | 1 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0019 | 0.0719 | 0.139 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0028 | 0.4456 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0026 | 0.3709 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.