Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | cathepsin C | 0.0094 | 0.0521 | 0.0743 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0225 | 0.2646 | 0.3773 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0256 | 0.3153 | 0.4496 |
Schistosoma mansoni | cathepsin B (C01 family) | 0.0094 | 0.0521 | 0.0743 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0493 | 0.7014 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0331 | 0.4382 | 0.6247 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0331 | 0.4382 | 0.6247 |
Leishmania major | cathepsin L-like protease | 0.0493 | 0.7014 | 0.6615 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0256 | 0.3153 | 0.4054 |
Schistosoma mansoni | dipeptidyl-peptidase I (C01 family) | 0.0094 | 0.0521 | 0.0743 |
Giardia lamblia | Cathepsin B precursor | 0.0135 | 0.1179 | 1 |
Echinococcus granulosus | cathepsin b | 0.0225 | 0.2646 | 0.3773 |
Giardia lamblia | Cathepsin B precursor | 0.0135 | 0.1179 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0493 | 0.7014 | 1 |
Leishmania major | cathepsin L-like protease | 0.0493 | 0.7014 | 0.6615 |
Entamoeba histolytica | cysteine protease, putative | 0.0256 | 0.3153 | 0.4054 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.0521 | 0.0743 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0069 | 0.0099 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0162 | 0.1618 | 0.2307 |
Brugia malayi | cathepsin L precursor | 0.0094 | 0.0521 | 0.0743 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.1618 | 0.2307 |
Toxoplasma gondii | cathepsin CPL | 0.0493 | 0.7014 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0256 | 0.3153 | 0.4496 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0493 | 0.7014 | 1 |
Onchocerca volvulus | 0.0493 | 0.7014 | 1 | |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.0094 | 0.0521 | 0.0743 |
Brugia malayi | calpain family protein 1 | 0.0107 | 0.0725 | 0.1034 |
Leishmania major | cathepsin L-like protease | 0.0493 | 0.7014 | 0.6615 |
Loa Loa (eye worm) | hypothetical protein | 0.0331 | 0.4382 | 0.6247 |
Echinococcus multilocularis | cysteine protease | 0.0493 | 0.7014 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0256 | 0.3153 | 0.4054 |
Brugia malayi | Cathepsin L-like precursor | 0.0493 | 0.7014 | 1 |
Loa Loa (eye worm) | calpain family protein 1 | 0.0107 | 0.0725 | 0.1034 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0256 | 0.3153 | 0.2239 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0493 | 0.7014 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0094 | 0.0521 | 0.0743 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0118 | 0.0909 | 0.1297 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0493 | 0.7014 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0331 | 0.4382 | 0.6247 |
Onchocerca volvulus | 0.0493 | 0.7014 | 1 | |
Onchocerca volvulus | Cathepsin L homolog | 0.0094 | 0.0521 | 0.0743 |
Entamoeba histolytica | cysteine protease, putative | 0.0256 | 0.3153 | 0.4054 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0256 | 0.3153 | 0.2777 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0256 | 0.3153 | 0.4054 |
Onchocerca volvulus | 0.0493 | 0.7014 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.0493 | 0.7014 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0225 | 0.2646 | 0.3773 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0331 | 0.4382 | 0.5946 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0094 | 0.0521 | 0.0743 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0493 | 0.7014 | 1 |
Plasmodium vivax | vivapain-3 | 0.0256 | 0.3153 | 0.4054 |
Schistosoma mansoni | cathepsin S (C01 family) | 0.0094 | 0.0521 | 0.0743 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0493 | 0.7014 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0135 | 0.1179 | 0.0693 |
Onchocerca volvulus | 0.0331 | 0.4382 | 0.6247 | |
Brugia malayi | Cathepsin L-like precursor | 0.0493 | 0.7014 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0493 | 0.7014 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0256 | 0.3153 | 0.4054 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0493 | 0.7014 | 1 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0094 | 0.0521 | 0.0743 |
Brugia malayi | cathepsin L-like cysteine proteinase | 0.0094 | 0.0521 | 0.0743 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0493 | 0.7014 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0493 | 0.7014 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0225 | 0.2646 | 0.3773 |
Schistosoma mansoni | cathepsin D (A01 family) | 0.0151 | 0.144 | 0.2054 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0493 | 0.7014 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.0725 | 0.1034 |
Brugia malayi | Cathepsin L-like precursor | 0.0162 | 0.1618 | 0.2307 |
Loa Loa (eye worm) | hypothetical protein | 0.0331 | 0.4382 | 0.6247 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0493 | 0.7014 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0493 | 0.7014 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.0528 | 0.0753 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.0521 | 0.0743 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0493 | 0.7014 | 1 |
Onchocerca volvulus | 0.0493 | 0.7014 | 1 | |
Onchocerca volvulus | 0.0493 | 0.7014 | 1 | |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0256 | 0.3153 | 0.4496 |
Echinococcus granulosus | cathepsin l1 | 0.0331 | 0.4382 | 0.6247 |
Leishmania major | cathepsin L-like protease | 0.0493 | 0.7014 | 0.6615 |
Onchocerca volvulus | 0.0493 | 0.7014 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0493 | 0.7014 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0225 | 0.2646 | 0.3773 |
Loa Loa (eye worm) | cysteine protease | 0.0493 | 0.7014 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0493 | 0.7014 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0256 | 0.3153 | 0.4054 |
Brugia malayi | Cathepsin L-like precursor | 0.0493 | 0.7014 | 1 |
Echinococcus granulosus | cathepsin L | 0.0256 | 0.3153 | 0.4496 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0162 | 0.1618 | 0.2307 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0225 | 0.2646 | 0.2242 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0493 | 0.7014 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0135 | 0.1179 | 0.1012 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0094 | 0.0521 | 0.0743 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0493 | 0.7014 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0493 | 0.7014 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.0521 | 0.0743 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0493 | 0.7014 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0256 | 0.3153 | 0.4054 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0094 | 0.0521 | 0.0743 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0256 | 0.3153 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0493 | 0.7014 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.1618 | 0.2307 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0493 | 0.7014 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0256 | 0.3153 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0493 | 0.7014 | 1 |
Toxoplasma gondii | cathepsin B | 0.0135 | 0.1179 | 0.1012 |
Schistosoma mansoni | cathepsin D (A01 family) | 0.0151 | 0.144 | 0.2054 |
Plasmodium vivax | vivapain-1 | 0.0256 | 0.3153 | 0.4054 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0493 | 0.7014 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0493 | 0.7014 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0256 | 0.3153 | 0.4496 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0493 | 0.7014 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0256 | 0.3153 | 0.2239 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0493 | 0.7014 | 1 |
Echinococcus granulosus | cysteine protease | 0.0256 | 0.3153 | 0.4496 |
Giardia lamblia | Cathepsin B precursor | 0.0135 | 0.1179 | 1 |
Schistosoma mansoni | cathepsin s | 0.0162 | 0.1618 | 0.2307 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0225 | 0.2646 | 0.3773 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0493 | 0.7014 | 1 |
Echinococcus granulosus | cathepsin L | 0.0094 | 0.0521 | 0.0743 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0094 | 0.0521 | 0.0743 |
Onchocerca volvulus | 0.0094 | 0.0521 | 0.0743 | |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0162 | 0.1618 | 0.1157 |
Echinococcus multilocularis | family C2 unassigned peptidase (C02 family) | 0.0118 | 0.0909 | 0.1297 |
Entamoeba histolytica | cysteine protease, putative | 0.0493 | 0.7014 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0493 | 0.7014 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.0493 | 0.7014 | 0.6615 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.0521 | 0.0743 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0256 | 0.3153 | 0.2777 |
Echinococcus multilocularis | cathepsin b | 0.0225 | 0.2646 | 0.3773 |
Brugia malayi | fibroinase precursor | 0.0094 | 0.0521 | 0.0743 |
Onchocerca volvulus | 0.0066 | 0.0069 | 0.0099 | |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0162 | 0.1618 | 0.1157 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0094 | 0.0521 | 0.0743 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0493 | 0.7014 | 1 |
Leishmania major | cathepsin L-like protease | 0.0493 | 0.7014 | 0.6615 |
Plasmodium vivax | vivapain-2 | 0.0493 | 0.7014 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0256 | 0.3153 | 0.4054 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0266 | 0.038 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0256 | 0.3153 | 0.4054 |
Brugia malayi | Cathepsin L-like precursor | 0.0493 | 0.7014 | 1 |
Onchocerca volvulus | 0.0493 | 0.7014 | 1 | |
Loa Loa (eye worm) | cysteine proteinase cathepsin Z | 0.0094 | 0.0521 | 0.0743 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0493 | 0.7014 | 1 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0118 | 0.0909 | 0.1297 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0135 | 0.1179 | 0.168 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0094 | 0.0521 | 0.0743 |
Echinococcus multilocularis | cathepsin L | 0.0094 | 0.0521 | 0.0743 |
Loa Loa (eye worm) | fibroinase | 0.0493 | 0.7014 | 1 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.0162 | 0.1618 | 0.2307 |
Brugia malayi | Cathepsin L-like precursor | 0.0331 | 0.4382 | 0.6247 |
Echinococcus granulosus | calpain A | 0.0119 | 0.0917 | 0.1307 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0493 | 0.7014 | 0.6849 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.0094 | 0.0521 | 0.0743 |
Echinococcus granulosus | cathepsin b | 0.0225 | 0.2646 | 0.3773 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0493 | 0.7014 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0256 | 0.3153 | 0.4054 |
Echinococcus multilocularis | cathepsin L | 0.0256 | 0.3153 | 0.4496 |
Plasmodium vivax | vivapain-2 | 0.0493 | 0.7014 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0493 | 0.7014 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0256 | 0.3153 | 0.2777 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0493 | 0.7014 | 1 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0107 | 0.0725 | 0.1034 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.0521 | 0.0743 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0515 | 0.7368 | 0.7223 |
Plasmodium vivax | unspecified product | 0.0256 | 0.3153 | 0.4054 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.0094 | 0.0521 | 0.0743 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0331 | 0.4382 | 0.5946 |
Onchocerca volvulus | Cathepsin F homolog | 0.0493 | 0.7014 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.0521 | 0.0743 |
Entamoeba histolytica | cysteine protease, putative | 0.0256 | 0.3153 | 0.4054 |
Echinococcus granulosus | family C2 unassigned peptidase C02 family | 0.0118 | 0.0909 | 0.1297 |
Trypanosoma cruzi | cysteine protease, putative | 0.0256 | 0.3153 | 0.2777 |
Loa Loa (eye worm) | cathepsin B | 0.0135 | 0.1179 | 0.168 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0493 | 0.7014 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0493 | 0.7014 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0256 | 0.3153 | 0.4496 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0493 | 0.7014 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0256 | 0.3153 | 0.4054 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0493 | 0.7014 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0256 | 0.3153 | 0.4054 |
Brugia malayi | cathepsin L-like precursor | 0.0331 | 0.4382 | 0.6247 |
Echinococcus multilocularis | cathepsin b | 0.0225 | 0.2646 | 0.3773 |
Entamoeba histolytica | cysteine protease, putative | 0.0256 | 0.3153 | 0.4054 |
Brugia malayi | Cathepsin L-like precursor | 0.0493 | 0.7014 | 1 |
Echinococcus multilocularis | calpain family protein 1, d | 0.0079 | 0.0266 | 0.038 |
Schistosoma mansoni | subfamily C1A non-peptidase homologue (C01 family) | 0.0094 | 0.0521 | 0.0743 |
Entamoeba histolytica | cysteine proteinase 2 | 0.0256 | 0.3153 | 0.4054 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0331 | 0.4382 | 0.5946 |
Loa Loa (eye worm) | hypothetical protein | 0.0493 | 0.7014 | 1 |
Plasmodium vivax | unspecified product | 0.0162 | 0.1618 | 0.169 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0278 | 0.3508 | 0.3151 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0493 | 0.7014 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0493 | 0.7014 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0493 | 0.7014 | 1 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.0094 | 0.0521 | 0.0743 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0493 | 0.7014 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0493 | 0.7014 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0256 | 0.3153 | 0.2777 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0256 | 0.3153 | 0.4496 |
Brugia malayi | cahepsin L-like non-peptiedase homolog | 0.0094 | 0.0521 | 0.0743 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0256 | 0.3153 | 0.4054 |
Brugia malayi | cathepsin B-like cysteine proteinase | 0.0225 | 0.2646 | 0.3773 |
Entamoeba histolytica | cysteine protease, putative | 0.0256 | 0.3153 | 0.4054 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0094 | 0.0521 | 0.0743 |
Echinococcus multilocularis | calpain A | 0.0119 | 0.0917 | 0.1307 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0094 | 0.0521 | 0.0743 |
Loa Loa (eye worm) | ctsf protein | 0.0493 | 0.7014 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0094 | 0.0521 | 0.0743 |
Entamoeba histolytica | cysteine protease, putative | 0.0256 | 0.3153 | 0.4054 |
Loa Loa (eye worm) | hypothetical protein | 0.0331 | 0.4382 | 0.6247 |
Brugia malayi | calpain family protein 1 | 0.0107 | 0.0725 | 0.1034 |
Echinococcus granulosus | cathepsin l1 | 0.0493 | 0.7014 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0256 | 0.3153 | 0.4054 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.1618 | 0.2307 |
Loa Loa (eye worm) | calpain family protein 1 | 0.0079 | 0.0266 | 0.038 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.