Detailed information for compound 1614256

Basic information

Technical information
  • TDR Targets ID: 1614256
  • Name: 1-[4-[2-(4-chlorophenyl)ethenyl]phenyl]-2-pip eridin-1-ylethanol
  • MW: 341.874 | Formula: C21H24ClNO
  • H donors: 1 H acceptors: 1 LogP: 4.85 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(c1ccc(cc1)/C=C/c1ccc(cc1)Cl)CN1CCCCC1
  • InChi: 1S/C21H24ClNO/c22-20-12-8-18(9-13-20)5-4-17-6-10-19(11-7-17)21(24)16-23-14-2-1-3-15-23/h4-13,21,24H,1-3,14-16H2/b5-4+
  • InChiKey: QJUBRQLMPOZVNB-SNAWJCMRSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 1-[4-[(E)-2-(4-chlorophenyl)ethenyl]phenyl]-2-piperidin-1-ylethanol
  • 1-[4-[2-(4-chlorophenyl)vinyl]phenyl]-2-(1-piperidyl)ethanol
  • 1-[4-[(E)-2-(4-chlorophenyl)vinyl]phenyl]-2-(1-piperidyl)ethanol
  • 1-[4-[2-(4-chlorophenyl)vinyl]phenyl]-2-piperidino-ethanol
  • 1-[4-[(E)-2-(4-chlorophenyl)vinyl]phenyl]-2-piperidino-ethanol
  • 1-[4-[2-(4-chlorophenyl)ethenyl]phenyl]-2-piperidin-1-yl-ethanol
  • 1-[4-[(E)-2-(4-chlorophenyl)ethenyl]phenyl]-2-piperidin-1-yl-ethanol
  • 1-Piperidineethanol, .alpha.-[p-(p-chlorostyryl)phenyl]-
  • 1-Piperidineethanol, .alpha.[4-[2-(4-chlorophenyl)ethenyl]phenyl]-
  • NSC26040
  • NCI60_002079

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0195 0.627 1
Brugia malayi Latrophilin receptor protein 2 0.0047 0.0574 0.0916
Brugia malayi Nuclear hormone receptor-like 1 0.0195 0.627 1
Brugia malayi Thioredoxin reductase 0.0092 0.2299 0.3666
Brugia malayi Steroid receptor seven-up type 2 0.0195 0.627 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0195 0.627 1
Brugia malayi nuclear hormone receptor family member odr-7 0.0092 0.2314 0.369
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0103 0.2737 0.2737
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0047 0.0574 0.0916
Onchocerca volvulus Protein ultraspiracle homolog 0.0195 0.627 1
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0047 0.0574 0.0916
Brugia malayi conserved hypotetical protein 0.0092 0.2314 0.369
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0195 0.627 0.627
Loa Loa (eye worm) hypothetical protein 0.0195 0.627 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0114 0.0181
Loa Loa (eye worm) hypothetical protein 0.0195 0.627 1
Mycobacterium tuberculosis Probable reductase 0.0209 0.6806 0.8837
Loa Loa (eye worm) hypothetical protein 0.0148 0.4449 0.7054
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0195 0.627 1
Schistosoma mansoni hypothetical protein 0.0047 0.0574 0.0574
Schistosoma mansoni nuclear receptor nhr-48 0.0092 0.2314 0.2314
Loa Loa (eye worm) hypothetical protein 0.0103 0.2737 0.4285
Brugia malayi nuclear receptor RXR 0.0103 0.2737 0.4366
Loa Loa (eye worm) DR-78 0.0092 0.2314 0.36
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0092 0.2314 0.369
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0047 0.0574 0.0916
Plasmodium vivax thioredoxin reductase, putative 0.0092 0.2299 1
Brugia malayi tailless protein 0.0092 0.2314 0.369
Loa Loa (eye worm) hypothetical protein 0.0047 0.0574 0.0786
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0195 0.627 0.627
Brugia malayi latrophilin 2 splice variant baaae 0.0101 0.2656 0.4235
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0114 0.0114
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0195 0.627 0.627
Loa Loa (eye worm) steroid hormone receptor 0.0195 0.627 1
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0209 0.6806 0.8837
Loa Loa (eye worm) nuclear hormone receptor 0.0092 0.2314 0.36
Loa Loa (eye worm) hypothetical protein 0.0195 0.627 1
Echinococcus multilocularis jumonji domain containing protein 0.0039 0.0284 0.0453
Brugia malayi hypothetical protein 0.0092 0.2314 0.369
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0195 0.627 0.627
Schistosoma mansoni thyroid hormone receptor 0.0195 0.627 0.627
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0195 0.627 1
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0195 0.627 1
Brugia malayi ecdysteroid receptor 0.0195 0.627 1
Brugia malayi hypothetical protein 0.0155 0.472 0.7527
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0195 0.627 1
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0092 0.2314 0.369
Loa Loa (eye worm) hypothetical protein 0.0092 0.2314 0.36
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0092 0.2314 0.2314
Loa Loa (eye worm) hypothetical protein 0.0092 0.2314 0.36
Loa Loa (eye worm) hypothetical protein 0.0092 0.2314 0.36
Loa Loa (eye worm) hypothetical protein 0.0195 0.627 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0195 0.627 1
Echinococcus granulosus GPCR family 2 0.0047 0.0574 0.0916
Loa Loa (eye worm) hypothetical protein 0.0195 0.627 1
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0092 0.2318 0.3697
Plasmodium falciparum glutathione reductase 0.0092 0.2299 1
Brugia malayi Nuclear hormone receptor E75 0.0092 0.2314 0.369
Echinococcus granulosus nuclear receptor nhr 48 0.0092 0.2314 0.369
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0103 0.2737 0.4366
Loa Loa (eye worm) hypothetical protein 0.0103 0.2737 0.4285
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0195 0.627 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0195 0.627 1
Trypanosoma brucei trypanothione reductase 0.0092 0.2299 1
Loa Loa (eye worm) hypothetical protein 0.0092 0.2314 0.36
Mycobacterium tuberculosis Probable oxidoreductase 0.0233 0.7701 1
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0092 0.2314 0.2314
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0092 0.2314 0.369
Brugia malayi nuclear receptor NHR-88 0.0195 0.627 1
Echinococcus granulosus thyroid hormone receptor alpha 0.0092 0.2314 0.369
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0195 0.627 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0148 0.4449 0.7095
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0047 0.0574 0.0916
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0195 0.627 1
Loa Loa (eye worm) hypothetical protein 0.0103 0.2737 0.4285
Schistosoma mansoni zinc finger protein 0.0092 0.2314 0.2314
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0092 0.2314 0.369
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0195 0.627 1
Plasmodium falciparum thioredoxin reductase 0.0092 0.2299 1
Loa Loa (eye worm) hypothetical protein 0.0092 0.2314 0.36
Echinococcus granulosus Nuclear hormone receptor HR96 0.0092 0.2314 0.369
Loa Loa (eye worm) hypothetical protein 0.0092 0.2314 0.36
Brugia malayi hypothetical protein 0.0092 0.2314 0.369
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0047 0.0574 0.0916
Loa Loa (eye worm) glutathione reductase 0.0092 0.2299 0.3576
Brugia malayi ecdysone receptor 0.0092 0.2314 0.369
Echinococcus multilocularis thioredoxin glutathione reductase 0.0092 0.2299 0.3666
Echinococcus multilocularis thyroid hormone receptor alpha 0.0195 0.627 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0195 0.627 1
Echinococcus granulosus lysine specific demethylase 5A 0.0034 0.0088 0.0141
Echinococcus multilocularis FTZ F1 alpha 0.0195 0.627 1
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0092 0.2314 0.369
Loa Loa (eye worm) hypothetical protein 0.0195 0.627 1
Brugia malayi orphan nuclear receptor NR2E1 0.0092 0.2314 0.369
Schistosoma mansoni jumonji domain containing protein 0.0073 0.1591 0.1591
Loa Loa (eye worm) hypothetical protein 0.0195 0.627 1
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0092 0.2314 0.369
Loa Loa (eye worm) hypothetical protein 0.0101 0.2656 0.4153
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0195 0.627 0.627
Schistosoma mansoni hypothetical protein 0.0047 0.0574 0.0574
Loa Loa (eye worm) thioredoxin reductase 0.0092 0.2299 0.3576
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0092 0.2318 0.3697
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0195 0.627 1
Schistosoma mansoni hypothetical protein 0.0101 0.2656 0.2656
Schistosoma mansoni hypothetical protein 0.0047 0.0574 0.0574
Loa Loa (eye worm) hypothetical protein 0.0092 0.2314 0.36
Schistosoma mansoni nuclear hormone receptor 0.0092 0.2314 0.2314
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0092 0.2314 0.369
Loa Loa (eye worm) hypothetical protein 0.0092 0.2314 0.36
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0233 0.7701 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0114 0.0181
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0195 0.627 1
Schistosoma mansoni retinoic acid receptor RXR 0.0195 0.627 0.627
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0195 0.627 1
Schistosoma mansoni steroid hormone receptor ad4bp 0.0195 0.627 0.627
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0209 0.6806 0.8837
Entamoeba histolytica hypothetical protein 0.0035 0.0114 0.5
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0195 0.627 1
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0233 0.7701 1
Trypanosoma cruzi trypanothione reductase, putative 0.0092 0.2299 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0195 0.627 1
Schistosoma mansoni hypothetical protein 0.0035 0.0114 0.0114
Brugia malayi MH2 domain containing protein 0.0116 0.3241 0.5168
Brugia malayi nuclear receptor NHR-67 0.0092 0.2314 0.369
Echinococcus multilocularis GPCR, family 2 0.0047 0.0574 0.0916
Brugia malayi nuclear receptor NHR-88 0.0092 0.2314 0.369
Entamoeba histolytica hypothetical protein 0.0035 0.0114 0.5
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0195 0.627 1
Schistosoma mansoni nuclear hormone receptor 0.0092 0.2314 0.2314
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0195 0.627 1
Toxoplasma gondii thioredoxin reductase 0.0092 0.2299 1
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0103 0.2737 0.4366
Schistosoma mansoni thyroid hormone receptor 0.0195 0.627 0.627
Loa Loa (eye worm) jmjC domain-containing protein 0.0058 0.1011 0.1493
Brugia malayi jmjC domain containing protein 0.0034 0.0088 0.0141
Echinococcus granulosus thioredoxin glutathione reductase 0.0092 0.2299 0.3666
Onchocerca volvulus Bile acid receptor homolog 0.0195 0.627 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0195 0.627 1
Loa Loa (eye worm) transcription factor SMAD2 0.0116 0.3241 0.5099
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0092 0.2314 0.369
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0195 0.627 1
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0195 0.627 1
Brugia malayi nuclear hormone receptor family member nhr-6 0.0092 0.2314 0.369
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0195 0.627 1
Entamoeba histolytica hypothetical protein 0.0035 0.0114 0.5
Schistosoma mansoni jumonji/arid domain-containing protein 0.0034 0.0088 0.0088
Echinococcus multilocularis nuclear receptor nhr 48 0.0092 0.2314 0.369
Schistosoma mansoni coup transcription factor 0.0195 0.627 0.627
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0103 0.2737 0.4285
Schistosoma mansoni nuclear hormone receptor 0.0195 0.627 0.627
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0092 0.2314 0.36
Onchocerca volvulus 0.0155 0.472 0.608
Brugia malayi Nuclear hormone receptor E75 0.0092 0.2314 0.369
Brugia malayi hypothetical protein 0.0035 0.0114 0.0181
Schistosoma mansoni RAR-like nuclear receptor 0.0195 0.627 0.627
Loa Loa (eye worm) hypothetical protein 0.0092 0.2314 0.36
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0195 0.627 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.0034 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0195 0.627 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0195 0.627 1
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0195 0.627 1
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0209 0.6806 0.8837
Schistosoma mansoni hypothetical protein 0.0047 0.0574 0.0574
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0195 0.627 1
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0195 0.627 1
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0103 0.2737 0.2737
Onchocerca volvulus 0.0195 0.627 1
Loa Loa (eye worm) hypothetical protein 0.0155 0.472 0.7492
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0195 0.627 1
Brugia malayi photoreceptor-specific nuclear receptor 0.0195 0.627 1
Brugia malayi hypothetical protein 0.0103 0.2737 0.4366
Loa Loa (eye worm) MH2 domain-containing protein 0.0116 0.3241 0.5099
Mycobacterium tuberculosis Probable dehydrogenase 0.0209 0.6806 0.8837
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0195 0.627 0.627
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0233 0.7701 1
Loa Loa (eye worm) hypothetical protein 0.0092 0.2314 0.36
Brugia malayi nuclear hormone receptor 0.0092 0.2314 0.369
Brugia malayi nuclear receptor RXR 0.0092 0.2314 0.369
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0195 0.627 1
Brugia malayi Nuclear hormone receptor-like 1 0.0103 0.2737 0.4366
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0209 0.6806 0.8837
Echinococcus granulosus FTZ F1 alpha 0.0195 0.627 1
Entamoeba histolytica hypothetical protein 0.0035 0.0114 0.5
Loa Loa (eye worm) hypothetical protein 0.0048 0.0632 0.088
Brugia malayi glutathione reductase 0.0092 0.2299 0.3666
Loa Loa (eye worm) latrophilin receptor protein 2 0.0047 0.0574 0.0786
Echinococcus multilocularis lysine specific demethylase 5A 0.0034 0.0088 0.0141
Brugia malayi hypothetical protein 0.0103 0.2737 0.4366
Echinococcus granulosus Nuclear hormone receptor HR96 0.0092 0.2314 0.369
Loa Loa (eye worm) hypothetical protein 0.0092 0.2314 0.36
Echinococcus multilocularis ecdysone induced protein 78C 0.0195 0.627 1
Brugia malayi Nuclear hormone receptor-like 1 0.0103 0.2737 0.4366
Schistosoma mansoni nuclear receptor 0.0092 0.2314 0.2314
Plasmodium vivax glutathione reductase, putative 0.0092 0.2299 1
Loa Loa (eye worm) nuclear receptor NHR-67 0.0092 0.2314 0.36
Loa Loa (eye worm) hypothetical protein 0.0092 0.2314 0.36
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0148 0.4449 0.7054
Leishmania major trypanothione reductase 0.0092 0.2299 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0195 0.627 1
Brugia malayi steroid hormone receptor 0.0195 0.627 1
Loa Loa (eye worm) hypothetical protein 0.0092 0.2314 0.36
Schistosoma mansoni nuclear receptor 0.0092 0.2314 0.2314
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0195 0.627 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0195 0.627 1
Loa Loa (eye worm) hypothetical protein 0.0103 0.2737 0.4285
Loa Loa (eye worm) hypothetical protein 0.0103 0.2737 0.4285
Brugia malayi Calcitonin receptor-like protein seb-1 0.0148 0.4449 0.7095
Brugia malayi jmjC domain containing protein 0.0092 0.2318 0.3697
Brugia malayi nuclear hormone receptor 0.0195 0.627 1
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0092 0.2299 0.2985
Echinococcus granulosus jumonji domain containing protein 0.0039 0.0284 0.0453
Echinococcus granulosus ecdysone induced protein 78C 0.0195 0.627 1

Activities

Activity type Activity value Assay description Source Reference
GI50 (functional) -5.212 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.652 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.361 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.298 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.296 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.245 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4.22 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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