Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0023 | 0.0271 | 0.0269 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0011 | 0.0029 | 0.0037 |
Onchocerca volvulus | 0.0023 | 0.0271 | 0.0243 | |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0035 | 0.0521 | 0.4373 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0023 | 0.0271 | 0.0346 |
Echinococcus granulosus | subfamily S1A unassigned peptidase S01 family | 0.0402 | 0.7843 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0271 | 0.0269 |
Mycobacterium ulcerans | hypothetical protein | 0.0402 | 0.7843 | 1 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0015 | 0.0118 | 0.0187 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0029 | 0.0027 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.01 | 0.1819 | 0.8904 |
Onchocerca volvulus | Huntingtin homolog | 0.0143 | 0.2662 | 0.264 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0011 | 0.0029 | 0.0027 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0044 | 0.0692 | 1 |
Brugia malayi | hypothetical protein | 0.0011 | 0.0029 | 0.0027 |
Schistosoma mansoni | smad1 5 8 and | 0.0009 | 0.0002 | 0.0002 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0045 | 0.0704 | 0.0898 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0402 | 0.7843 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0239 | 0.2258 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0011 | 0.0032 | 0.003 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0023 | 0.0271 | 0.0346 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0055 | 0.0053 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.2002 | 0.2001 |
Brugia malayi | HSF-type DNA-binding domain containing protein | 0.011 | 0.2002 | 0.2001 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0015 | 0.0118 | 0.015 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0021 | 0.0239 | 0.211 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0055 | 0.0053 |
Brugia malayi | Pre-SET motif family protein | 0.0035 | 0.0521 | 0.0519 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0031 | 0.044 | 0.0438 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0011 | 0.0029 | 0.0027 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0011 | 0.0029 | 0.0037 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0402 | 0.7843 | 1 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0011 | 0.0029 | 0.0027 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0011 | 0.0029 | 0.0027 |
Echinococcus granulosus | apoptotic protease activating factor 1 | 0.0036 | 0.0531 | 0.0678 |
Onchocerca volvulus | Cell death protein 3 homolog | 0.0036 | 0.0531 | 0.0504 |
Brugia malayi | intermediate filament protein | 0.0031 | 0.044 | 0.0438 |
Brugia malayi | nuclear receptor NHR-88 | 0.0011 | 0.0029 | 0.0027 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0012 | 0.0055 | 0.007 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0015 | 0.0118 | 0.0187 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0012 | 0.0055 | 0.0053 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0023 | 0.0271 | 0.0346 |
Loa Loa (eye worm) | hypothetical protein | 0.0402 | 0.7843 | 0.7842 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0055 | 0.0053 |
Echinococcus multilocularis | cpg binding protein | 0.0034 | 0.0483 | 0.0616 |
Echinococcus multilocularis | Mastin | 0.0402 | 0.7843 | 1 |
Onchocerca volvulus | 0.0035 | 0.0521 | 0.0493 | |
Schistosoma mansoni | hypothetical protein | 0.0384 | 0.7495 | 0.9557 |
Leishmania major | DNA polymerase eta, putative | 0.0021 | 0.0239 | 0.211 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0023 | 0.0271 | 0.0346 |
Leishmania major | DNA polymerase kappa, putative | 0.0021 | 0.0239 | 0.211 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0015 | 0.0118 | 0.015 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0023 | 0.0271 | 0.0269 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0023 | 0.0271 | 0.0346 |
Brugia malayi | nuclear receptor RXR | 0.0012 | 0.0055 | 0.0053 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0428 | 0.0427 |
Loa Loa (eye worm) | hypothetical protein | 0.0402 | 0.7843 | 0.7842 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.01 | 0.1819 | 0.8904 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.0483 | 0.0616 |
Echinococcus multilocularis | dna polymerase eta | 0.0021 | 0.0239 | 0.0305 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0023 | 0.0271 | 0.0269 |
Onchocerca volvulus | 0.0402 | 0.7843 | 0.7836 | |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0017 | 0.0149 | 0.0147 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0029 | 0.0027 |
Echinococcus granulosus | cpg binding protein | 0.0034 | 0.0483 | 0.0616 |
Brugia malayi | Thioredoxin reductase | 0.0044 | 0.0692 | 0.0691 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0023 | 0.0271 | 0.0243 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0017 | 0.0149 | 0.0147 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0035 | 0.0521 | 0.0664 |
Schistosoma mansoni | smad1 5 8 and | 0.0009 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0029 | 0.0027 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0021 | 0.0239 | 0.0305 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.01 | 0.1819 | 0.8904 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0239 | 0.2258 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0029 | 0.0027 |
Giardia lamblia | DINP protein human, muc B family | 0.0021 | 0.0239 | 1 |
Brugia malayi | Trypsin family protein | 0.0402 | 0.7843 | 0.7842 |
Schistosoma mansoni | nuclear hormone receptor | 0.0011 | 0.0029 | 0.0037 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0021 | 0.0239 | 0.0305 |
Brugia malayi | Trypsin family protein | 0.0402 | 0.7843 | 0.7842 |
Echinococcus granulosus | dna polymerase eta | 0.0021 | 0.0239 | 0.0305 |
Echinococcus multilocularis | lamin | 0.0031 | 0.044 | 0.0561 |
Toxoplasma gondii | thioredoxin reductase | 0.0044 | 0.0692 | 0.6234 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0015 | 0.0118 | 0.022 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0061 | 0.104 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0011 | 0.0029 | 0.0027 |
Plasmodium falciparum | glutathione reductase | 0.0044 | 0.0692 | 1 |
Mycobacterium tuberculosis | Probable reductase | 0.01 | 0.1819 | 0.8904 |
Entamoeba histolytica | hypothetical protein | 0.0082 | 0.1444 | 0.6834 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0021 | 0.0239 | 0.1169 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0015 | 0.0118 | 0.5 |
Schistosoma mansoni | intermediate filament proteins | 0.0031 | 0.044 | 0.0561 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0023 | 0.0271 | 0.0346 |
Schistosoma mansoni | nuclear hormone receptor | 0.0011 | 0.0029 | 0.0037 |
Echinococcus granulosus | smad | 0.0009 | 0.0002 | 0.0002 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0011 | 0.0029 | 0.0037 |
Echinococcus multilocularis | transmembrane protease serine 3 | 0.0402 | 0.7843 | 1 |
Echinococcus granulosus | glycoprotein Antigen 5 | 0.0402 | 0.7843 | 1 |
Onchocerca volvulus | 0.0402 | 0.7843 | 0.7836 | |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0011 | 0.0029 | 0.0037 |
Onchocerca volvulus | 0.0036 | 0.0531 | 0.0504 | |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.01 | 0.1819 | 0.8904 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0402 | 0.7843 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0402 | 0.7843 | 0.7842 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0402 | 0.7843 | 1 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.01 | 0.1819 | 0.8904 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0021 | 0.0239 | 0.0448 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0402 | 0.7843 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0143 | 0.2662 | 0.266 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0531 | 0.0529 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0104 | 0.0102 |
Echinococcus multilocularis | glycoprotein Antigen 5 | 0.0402 | 0.7843 | 1 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0015 | 0.0115 | 0.0147 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0009 | 0.0002 | 0.0002 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0402 | 0.7843 | 1 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0015 | 0.0118 | 0.015 |
Brugia malayi | hypothetical protein | 0.0012 | 0.0055 | 0.0053 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0015 | 0.0118 | 0.015 |
Onchocerca volvulus | Huntingtin homolog | 0.0143 | 0.2662 | 0.264 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0023 | 0.0271 | 0.0269 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0011 | 0.0029 | 0.0027 |
Onchocerca volvulus | 0.0402 | 0.7843 | 0.7836 | |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0023 | 0.0271 | 0.0269 |
Echinococcus granulosus | caspase 2 | 0.0036 | 0.0531 | 0.0678 |
Loa Loa (eye worm) | hypothetical protein | 0.0402 | 0.7843 | 0.7842 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0139 | 0.2589 | 0.2588 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.01 | 0.1819 | 0.8904 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0021 | 0.0239 | 0.0237 |
Onchocerca volvulus | 0.0402 | 0.7843 | 0.7836 | |
Brugia malayi | hypothetical protein | 0.0012 | 0.0055 | 0.0053 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0029 | 0.0027 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0011 | 0.0037 | 0.0035 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0012 | 0.0055 | 0.0053 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0015 | 0.0118 | 0.0187 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0023 | 0.0271 | 0.0269 |
Echinococcus granulosus | lamin dm0 | 0.0031 | 0.044 | 0.0561 |
Schistosoma mansoni | hypothetical protein | 0.0402 | 0.7843 | 1 |
Echinococcus multilocularis | musashi | 0.0031 | 0.044 | 0.0561 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0112 | 0.2043 | 1 |
Brugia malayi | Trypsin family protein | 0.0402 | 0.7843 | 0.7842 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0023 | 0.0271 | 0.0269 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0023 | 0.0271 | 0.0269 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0021 | 0.0239 | 0.211 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0011 | 0.0029 | 0.0037 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0402 | 0.7843 | 1 |
Echinococcus multilocularis | Peptidase S1 S6, chymotrypsin Hap | 0.0402 | 0.7843 | 1 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0021 | 0.0239 | 0.0237 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0023 | 0.0271 | 0.0269 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0011 | 0.0035 | 0.0044 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0023 | 0.0271 | 0.0269 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0023 | 0.0271 | 0.0269 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0112 | 0.2043 | 1 |
Trypanosoma brucei | trypanothione reductase | 0.0044 | 0.0692 | 1 |
Brugia malayi | Trypsin family protein | 0.0402 | 0.7843 | 0.7842 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0023 | 0.0271 | 0.0269 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0035 | 0.0521 | 0.0664 |
Loa Loa (eye worm) | histone methyltransferase | 0.0011 | 0.0035 | 0.0033 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0239 | 0.2258 |
Entamoeba histolytica | heat shock transcription factor, putative | 0.011 | 0.2002 | 1 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0009 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0029 | 0.0027 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0045 | 0.0704 | 0.0898 |
Echinococcus multilocularis | Smad4 | 0.0009 | 0.0002 | 0.0002 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0021 | 0.0239 | 0.2258 |
Onchocerca volvulus | 0.0031 | 0.044 | 0.0412 | |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0104 | 0.0102 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0023 | 0.0271 | 0.0269 |
Echinococcus multilocularis | enteropeptidase | 0.0402 | 0.7843 | 1 |
Brugia malayi | hypothetical protein | 0.0082 | 0.1444 | 0.1442 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0239 | 0.2258 |
Entamoeba histolytica | heat shock transcription factor, putative | 0.011 | 0.2002 | 1 |
Echinococcus multilocularis | dna polymerase kappa | 0.0021 | 0.0239 | 0.0305 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0029 | 0.0027 |
Schistosoma mansoni | zinc finger protein | 0.0011 | 0.0029 | 0.0037 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0402 | 0.7843 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0402 | 0.7843 | 0.7842 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0029 | 0.0027 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0021 | 0.0239 | 0.211 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0023 | 0.0271 | 0.0346 |
Brugia malayi | conserved hypotetical protein | 0.0011 | 0.0029 | 0.0027 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0011 | 0.0029 | 0.0037 |
Brugia malayi | nuclear receptor NHR-88 | 0.0023 | 0.0271 | 0.0269 |
Entamoeba histolytica | heat shock transcription factor, putative | 0.011 | 0.2002 | 1 |
Onchocerca volvulus | 0.0031 | 0.044 | 0.0412 | |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0239 | 0.2258 |
Brugia malayi | glutathione reductase | 0.0044 | 0.0692 | 0.0691 |
Brugia malayi | hypothetical protein | 0.0143 | 0.2662 | 0.266 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0023 | 0.0271 | 0.0346 |
Echinococcus granulosus | intermediate filament protein | 0.0031 | 0.044 | 0.0561 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0521 | 0.0519 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0402 | 0.7843 | 1 |
Loa Loa (eye worm) | trypsin family protein | 0.0402 | 0.7843 | 0.7842 |
Echinococcus multilocularis | smad | 0.0009 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0271 | 0.0269 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0023 | 0.0271 | 0.0269 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0044 | 0.0692 | 0.0691 |
Onchocerca volvulus | 0.0276 | 0.5335 | 0.5322 | |
Schistosoma mansoni | smad | 0.0009 | 0.0002 | 0.0002 |
Entamoeba histolytica | hypothetical protein | 0.0082 | 0.1444 | 0.6834 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0023 | 0.0271 | 0.0269 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0029 | 0.0027 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0012 | 0.0055 | 0.007 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0011 | 0.0029 | 0.0037 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0021 | 0.0239 | 0.0448 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0023 | 0.0271 | 0.0269 |
Echinococcus granulosus | transmembrane protease serine 3 | 0.0402 | 0.7843 | 1 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0044 | 0.0692 | 1 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0015 | 0.0118 | 0.022 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0011 | 0.0029 | 0.0037 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0023 | 0.0271 | 0.0346 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0012 | 0.0055 | 0.0053 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0035 | 0.0521 | 0.0664 |
Onchocerca volvulus | 0.0402 | 0.7843 | 0.7836 | |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0239 | 0.2258 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0015 | 0.0118 | 0.0576 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0011 | 0.0029 | 0.0027 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0015 | 0.0118 | 0.015 |
Schistosoma mansoni | DNA polymerase eta | 0.0021 | 0.0239 | 0.0305 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0023 | 0.0271 | 0.0269 |
Echinococcus granulosus | Smad4 | 0.0009 | 0.0002 | 0.0002 |
Brugia malayi | Chymotrypsin-like protease CTRL-1 precursor | 0.0402 | 0.7843 | 0.7842 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0023 | 0.0271 | 0.0346 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0009 | 0.0002 | 0.0002 |
Echinococcus multilocularis | geminin | 0.0384 | 0.7495 | 0.9557 |
Schistosoma mansoni | hypothetical protein | 0.0082 | 0.1444 | 0.1841 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0035 | 0.0521 | 0.0664 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0271 | 0.0269 |
Plasmodium vivax | SET domain protein, putative | 0.0035 | 0.0521 | 0.7014 |
Brugia malayi | Cell death protein 3 precursor | 0.0036 | 0.0531 | 0.0529 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0011 | 0.0029 | 0.0037 |
Echinococcus granulosus | Mastin | 0.0402 | 0.7843 | 1 |
Brugia malayi | nuclear receptor NHR-67 | 0.0011 | 0.0029 | 0.0027 |
Echinococcus granulosus | geminin | 0.0384 | 0.7495 | 0.9557 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0082 | 0.1444 | 0.1841 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0023 | 0.0271 | 0.0346 |
Brugia malayi | hypothetical protein | 0.0402 | 0.7843 | 0.7842 |
Schistosoma mansoni | thyroid hormone receptor | 0.0023 | 0.0271 | 0.0346 |
Schistosoma mansoni | nuclear receptor | 0.0011 | 0.0029 | 0.0037 |
Schistosoma mansoni | nuclear hormone receptor | 0.0023 | 0.0271 | 0.0346 |
Brugia malayi | ecdysone receptor | 0.0011 | 0.0029 | 0.0027 |
Schistosoma mansoni | hypothetical protein | 0.0402 | 0.7843 | 1 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0012 | 0.0055 | 0.007 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.0029 | 0.0037 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0015 | 0.0115 | 0.0147 |
Brugia malayi | CXXC zinc finger family protein | 0.0032 | 0.0447 | 0.0445 |
Echinococcus granulosus | Peptidase S1 S6 chymotrypsin Hap | 0.0402 | 0.7843 | 1 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0021 | 0.0239 | 0.0305 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0011 | 0.0037 | 0.0035 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0023 | 0.0271 | 0.0346 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0023 | 0.0271 | 0.0269 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.0447 | 0.057 |
Loa Loa (eye worm) | hypothetical protein | 0.0402 | 0.7843 | 0.7842 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0023 | 0.0271 | 0.0346 |
Schistosoma mansoni | hypothetical protein | 0.0028 | 0.0381 | 0.0485 |
Echinococcus multilocularis | caspase 2 | 0.0036 | 0.0531 | 0.0678 |
Schistosoma mansoni | thyroid hormone receptor | 0.0023 | 0.0271 | 0.0346 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0029 | 0.0027 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0023 | 0.0271 | 0.0346 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0015 | 0.0118 | 0.0116 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0023 | 0.0271 | 0.0346 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0271 | 0.0269 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0023 | 0.0271 | 0.0269 |
Treponema pallidum | NADH oxidase | 0.0015 | 0.0118 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0069 | 0.1183 | 0.1509 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0023 | 0.0271 | 0.0346 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0021 | 0.0239 | 0.0305 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0029 | 0.0027 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0402 | 0.7843 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0115 | 0.0114 |
Leishmania major | trypanothione reductase | 0.0044 | 0.0692 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0082 | 0.1444 | 0.1841 |
Brugia malayi | Trypsin-like protease protein 5 | 0.0402 | 0.7843 | 0.7842 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0015 | 0.0118 | 0.015 |
Brugia malayi | ecdysteroid receptor | 0.0023 | 0.0271 | 0.0269 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0012 | 0.0055 | 0.007 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0015 | 0.0118 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0402 | 0.7843 | 0.7842 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0112 | 0.2043 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0035 | 0.0521 | 0.0664 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0023 | 0.0271 | 0.0346 |
Onchocerca volvulus | 0.0032 | 0.0447 | 0.0419 | |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0402 | 0.7843 | 1 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0402 | 0.7843 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0021 | 0.0239 | 0.211 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0035 | 0.0521 | 0.0664 |
Schistosoma mansoni | Smad4 | 0.0009 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0143 | 0.2662 | 0.266 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0271 | 0.0269 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0139 | 0.2589 | 0.2588 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0271 | 0.0269 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0023 | 0.0271 | 0.0269 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0082 | 0.1444 | 0.1841 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0239 | 0.0237 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0044 | 0.0692 | 0.3389 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0029 | 0.0027 |
Schistosoma mansoni | smad1 5 8 and | 0.0009 | 0.0002 | 0.0002 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0023 | 0.0271 | 0.0269 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0033 | 0.0481 | 0.0614 |
Plasmodium vivax | glutathione reductase, putative | 0.0044 | 0.0692 | 1 |
Echinococcus multilocularis | subfamily S1A unassigned peptidase (S01 family) | 0.0402 | 0.7843 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0021 | 0.0239 | 0.2258 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0011 | 0.0035 | 0.0044 |
Trypanosoma brucei | unspecified product | 0.0021 | 0.0239 | 0.2258 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0402 | 0.7843 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0021 | 0.0239 | 0.2258 |
Echinococcus granulosus | enteropeptidase | 0.0402 | 0.7843 | 1 |
Echinococcus multilocularis | lamin dm0 | 0.0031 | 0.044 | 0.0561 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0055 | 0.0053 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0009 | 0.0002 | 0.0002 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0239 | 0.2258 |
Schistosoma mansoni | lamin | 0.0031 | 0.044 | 0.0561 |
Trichomonas vaginalis | set domain proteins, putative | 0.0276 | 0.5335 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0402 | 0.7843 | 1 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0021 | 0.0239 | 0.0237 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0032 | 0.0447 | 0.0445 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0023 | 0.0271 | 0.0346 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0531 | 0.0529 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0531 | 0.0529 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0009 | 0.0002 | 0.0002 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0011 | 0.0029 | 0.0027 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0023 | 0.0271 | 0.0243 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0031 | 0.044 | 0.0438 |
Brugia malayi | steroid hormone receptor | 0.0023 | 0.0271 | 0.0269 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0402 | 0.7843 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0384 | 0.7495 | 0.9557 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0271 | 0.0269 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0402 | 0.7843 | 1 |
Onchocerca volvulus | Heat shock factor protein 2 homolog | 0.011 | 0.2002 | 0.1979 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0023 | 0.0271 | 0.0269 |
Brugia malayi | MH2 domain containing protein | 0.0139 | 0.2589 | 0.2588 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0023 | 0.0271 | 0.0269 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0021 | 0.0239 | 0.0305 |
Onchocerca volvulus | 0.0402 | 0.7843 | 0.7836 | |
Brugia malayi | tailless protein | 0.0011 | 0.0029 | 0.0027 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0023 | 0.0271 | 0.0346 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0023 | 0.0271 | 0.0346 |
Entamoeba histolytica | hypothetical protein | 0.0082 | 0.1444 | 0.6834 |
Schistosoma mansoni | lamin | 0.0031 | 0.044 | 0.0561 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0035 | 0.0521 | 0.0664 |
Schistosoma mansoni | coup transcription factor | 0.0023 | 0.0271 | 0.0346 |
Echinococcus granulosus | lamin | 0.0031 | 0.044 | 0.0561 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0402 | 0.7843 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0402 | 0.7843 | 1 |
Brugia malayi | hypothetical protein | 0.0011 | 0.0029 | 0.0027 |
Echinococcus granulosus | FTZ F1 alpha | 0.0023 | 0.0271 | 0.0346 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.0029 | 0.0037 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0239 | 0.2258 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0239 | 0.2258 |
Entamoeba histolytica | hypothetical protein | 0.0082 | 0.1444 | 0.6834 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0271 | 0.0269 |
Loa Loa (eye worm) | glutathione reductase | 0.0044 | 0.0692 | 0.0691 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0011 | 0.0029 | 0.0037 |
Echinococcus multilocularis | apoptotic protease activating factor 1 | 0.0036 | 0.0531 | 0.0678 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0015 | 0.0118 | 1 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0112 | 0.2043 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0021 | 0.0239 | 0.211 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0021 | 0.0239 | 0.2258 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0029 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0055 | 0.0053 |
Brugia malayi | Pre-SET motif family protein | 0.0243 | 0.4666 | 0.4665 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0021 | 0.0239 | 0.0305 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0023 | 0.0271 | 0.0346 |
Schistosoma mansoni | nuclear receptor | 0.0011 | 0.0029 | 0.0037 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0011 | 0.0029 | 0.0037 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0023 | 0.0271 | 0.0346 |
Loa Loa (eye worm) | intermediate filament protein | 0.0031 | 0.044 | 0.0438 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0021 | 0.0239 | 0.211 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0011 | 0.0029 | 0.0027 |
Brugia malayi | nuclear hormone receptor | 0.0023 | 0.0271 | 0.0269 |
Echinococcus granulosus | dna polymerase kappa | 0.0021 | 0.0239 | 0.0305 |
Schistosoma mansoni | caspase-7 (C14 family) | 0.0036 | 0.0531 | 0.0678 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0531 | 0.0678 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0239 | 0.2258 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0402 | 0.7843 | 1 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0011 | 0.0029 | 0.0037 |
Plasmodium falciparum | thioredoxin reductase | 0.0044 | 0.0692 | 1 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0243 | 0.4666 | 0.4665 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.044 | 0.0438 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0021 | 0.0239 | 0.1169 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.0483 | 0.0616 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0023 | 0.0271 | 0.0346 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0023 | 0.0271 | 0.0269 |
Brugia malayi | nuclear receptor RXR | 0.0011 | 0.0029 | 0.0027 |
Loa Loa (eye worm) | DR-78 | 0.0011 | 0.0029 | 0.0027 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0023 | 0.0271 | 0.0346 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0023 | 0.0271 | 0.0243 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0011 | 0.0029 | 0.0027 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0011 | 0.0029 | 0.0037 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0023 | 0.0271 | 0.0346 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0015 | 0.0118 | 0.0187 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0023 | 0.0271 | 0.0346 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI50 (functional) | -6.37 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.955 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.938 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.868 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.812 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.796 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.707 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.677 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.646 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.643 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.51 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.