Detailed information for compound 1619928

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 503.384 | Formula: C28H23BrO4
  • H donors: 2 H acceptors: 2 LogP: 7.47 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 2
  • SMILES: Brc1ccc(c2c1CCc1ccc(cc1)Oc1cc(CCc3cc(O2)ccc3)ccc1O)O
  • InChi: 1S/C28H23BrO4/c29-24-13-15-26(31)28-23(24)12-8-18-6-10-21(11-7-18)32-27-17-20(9-14-25(27)30)5-4-19-2-1-3-22(16-19)33-28/h1-3,6-7,9-11,13-17,30-31H,4-5,8,12H2
  • InChiKey: LMVHHTKZWBBTGF-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni steroid dehydrogenase 0.0036 0.0021 0.0088
Onchocerca volvulus 0.0169 0.0169 0.2116
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0036 0.0021 0.0102
Brugia malayi dehydrogenases, short chain protein 2 0.0036 0.0021 0.0111
Brugia malayi nuclear hormone receptor family member nhr-6 0.0038 0.0023 0.0121
Echinococcus multilocularis Smad4 0.0022 0.0005 0.0005
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0036 0.0021 0.018
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0062 0.005 0.0173
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0036 0.0022 0.0155
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0061 0.0048 0.0599
Trypanosoma brucei DNA polymerase IV, putative 0.0061 0.0048 0.0241
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0036 0.0021 0.0088
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0194 0.0196 0.0685
Schistosoma mansoni myelin transcription factor 1 myt1 0.0077 0.0067 0.0279
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0036 0.0021 0.018
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0194 0.0196 0.0685
Loa Loa (eye worm) hypothetical protein 0.0036 0.0021 0.0109
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0036 0.0022 0.0179
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0086 0.0077 0.1029
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0027 0.0012 0.0054
Mycobacterium ulcerans short chain dehydrogenase 0.0036 0.0021 0.0273
Brugia malayi hypothetical protein 0.005 0.0037 0.0195
Schistosoma mansoni retinal dehydrogenase 0.0036 0.0021 0.0088
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0027 0.0012 0.0054
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0076 0.0065 0.0814
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0151 0.0149 0.0518
Leishmania major mitochondrial DNA polymerase beta 0.0193 0.0195 0.0995
Brugia malayi Patched family protein 0.005 0.0037 0.0195
Schistosoma mansoni SET domain protein 0.0018 0.0002 0.0005
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0081 0.0071 0.0245
Leishmania major 4-coumarate:coa ligase-like protein 0.0275 0.0285 0.1455
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0041 0.0027 0.0242
Onchocerca volvulus 0.005 0.0037 0.0451
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0032 0.0017 0.0206
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0036 0.0021 0.007
Echinococcus multilocularis importin subunit beta 1 0.004 0.0026 0.0025
Echinococcus multilocularis dna polymerase kappa 0.0061 0.0048 0.0048
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.008 0.007 0.0365
Echinococcus multilocularis jumonji domain containing protein 0.0027 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0038 0.0023 0.012
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0056 0.0043 0.0043
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0028 0.0012 0.005
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0036 0.0021 0.0212
Echinococcus granulosus pyruvate kinase 0.0042 0.0028 0.0114
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0024 0.0008 0.0041
Echinococcus granulosus carbonyl reductase 1 0.0036 0.0021 0.0087
Echinococcus granulosus Biotin lipoyl attachment 0.0063 0.0051 0.0212
Echinococcus multilocularis thyroid hormone receptor alpha 0.0175 0.0175 0.0174
Brugia malayi hypothetical protein 0.0056 0.0044 0.023
Loa Loa (eye worm) hypothetical protein 0.0038 0.0023 0.012
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0036 0.0021 0.0254
Loa Loa (eye worm) hypothetical protein 0.0081 0.0071 0.0375
Toxoplasma gondii oxidoreductase, putative 0.0036 0.0021 0.0102
Echinococcus multilocularis ecdysone induced protein 78C 0.008 0.007 0.0069
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0004 0.0041
Mycobacterium tuberculosis Probable acetyl-/propionyl-coenzyme A carboxylase alpha chain (alpha subunit) AccA2: biotin carboxylase + biotin carboxyl carrie 0.0682 0.0735 0.2576
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0076 0.0065 0.0814
Mycobacterium ulcerans short chain dehydrogenase 0.0036 0.0021 0.0273
Echinococcus multilocularis dnaJ subfamily B 0.2163 0.2369 0.2369
Loa Loa (eye worm) oxidoreductase 0.0036 0.0021 0.0109
Schistosoma mansoni survival motor neuron protein 0.0206 0.0209 0.088
Brugia malayi beta-lactamase 0.0086 0.0077 0.0404
Brugia malayi Patched family protein 0.005 0.0037 0.0195
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.008 0.007 0.0292
Schistosoma mansoni nuclear receptor nhr-48 0.0038 0.0023 0.0096
Entamoeba histolytica phosphofructokinase, putative 0.0151 0.0149 0.1606
Mycobacterium ulcerans acetyl-/propionyl-coenzyme a carboxylase alpha chain AccA1 0.0682 0.0735 1
Plasmodium vivax SET domain protein, putative 0.0096 0.0087 0.0618
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0036 0.0021 0.007
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0021 0.0111
Loa Loa (eye worm) hypothetical protein 0.0027 0.0011 0.0056
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0076 0.0065 0.0814
Plasmodium vivax hypothetical protein, conserved 0.0018 0.0001 0.0008
Trypanosoma cruzi dihydrolipoamide acetyltransferase precursor, putative 0.0063 0.0051 0.042
Echinococcus granulosus nuclear receptor 2DBD gamma 0.008 0.007 0.0291
Plasmodium falciparum carbamoyl phosphate synthetase 0.0154 0.0152 0.1075
Trichomonas vaginalis phosphofructokinase, putative 0.0041 0.0027 0.0324
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0077 0.0067 0.0066
Brugia malayi Nuclear hormone receptor family member nhr-31 0.008 0.007 0.0367
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0027 0.0012 0.0054
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0069 0.0058 0.0602
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0275 0.0285 0.3873
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0036 0.0021 0.0174
Leishmania major 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase, putative 0.0063 0.0051 0.0259
Brugia malayi Nuclear hormone receptor family member nhr-19 0.008 0.007 0.0367
Schistosoma mansoni hypothetical protein 0.0206 0.0209 0.088
Loa Loa (eye worm) hypothetical protein 0.005 0.0037 0.0194
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0081 0.0071 0.0501
Loa Loa (eye worm) PHD-finger family protein 0.0019 0.0003 0.0012
Echinococcus multilocularis Niemann Pick C1 protein 0.1186 0.1291 0.1291
Mycobacterium ulcerans acetyl/propionyl CoA carboxylase subunit beta 0.0243 0.025 0.3386
Brugia malayi protein C24B5.3 0.005 0.0037 0.0195
Echinococcus granulosus GTP binding nuclear protein Ran 0.0029 0.0014 0.0057
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0028 0.0012 0.0012
Brugia malayi Steroid receptor seven-up type 2 0.008 0.007 0.0367
Loa Loa (eye worm) hypothetical protein 0.0103 0.0096 0.0504
Echinococcus granulosus lysine specific demethylase 5A 0.0034 0.0019 0.0079
Mycobacterium ulcerans short chain dehydrogenase 0.0036 0.0021 0.0273
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0058 0.0046 0.0567
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0044 0.0539
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.002 0.0019
Treponema pallidum DNA ligase (lig) 0.0056 0.0044 0.1055
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0036 0.0021 0.018
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0036 0.0021 0.0174
Loa Loa (eye worm) AGC/PKA protein kinase 0.0036 0.0022 0.0113
Echinococcus granulosus histone lysine methyltransferase setb 0.0107 0.01 0.0421
Onchocerca volvulus 0.0036 0.0021 0.0248
Echinococcus granulosus steroid dehydrogenase 0.0036 0.0021 0.0087
Loa Loa (eye worm) hypothetical protein 0.004 0.0026 0.0134
Mycobacterium leprae RECA PROTEIN (RECOMBINASE A) [CONTAINS: Mle RECA INTEIN]. 0.0083 0.0073 0.076
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0041 0.0027 0.0483
Schistosoma mansoni short chain dehydrogenase 0.0036 0.0021 0.0088
Echinococcus multilocularis lamin dm0 0.0022 0.0006 0.0005
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0044 0.003 0.0146
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0036 0.0021 0.0273
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0039 0.0025 0.0105
Brugia malayi Patched family protein 0.005 0.0037 0.0195
Toxoplasma gondii patched family protein 0.005 0.0037 0.0184
Echinococcus multilocularis mothers against decapentaplegic 5 0.0022 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0049 0.0036 0.0187
Toxoplasma gondii peptidylprolyl isomerase 0.0024 0.0008 0.0033
Echinococcus granulosus thyroid hormone receptor alpha 0.0038 0.0023 0.0095
Schistosoma mansoni hypothetical protein 0.0343 0.0361 0.1521
Loa Loa (eye worm) dehydrogenase 0.0036 0.0021 0.0109
Brugia malayi AMP-binding enzyme family protein 0.0275 0.0285 0.1508
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0081 0.0071 0.0949
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0024 0.0289
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0027 0.0011 0.0045
Schistosoma mansoni importin beta-1 0.004 0.0026 0.0108
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0028 0.0012 0.0063
Onchocerca volvulus 0.005 0.0037 0.0451
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0044 0.003 0.0146
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0041 0.0027 0.019
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0027 0.0012 0.0134
Brugia malayi Myosin head containing protein 0.005 0.0037 0.0195
Trichomonas vaginalis glucosylceramidase, putative 0.0163 0.0161 0.2028
Echinococcus multilocularis pyruvate kinase 0.0042 0.0028 0.0027
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0056 0.0044 0.058
Toxoplasma gondii phosphofructokinase PFKII 0.0041 0.0027 0.0131
Leishmania major methylcrotonoyl-coa carboxylase biotinylated subunitprotein-like protein 0.0682 0.0735 0.375
Giardia lamblia Kinase, AGC PKA 0.0036 0.0022 0.0614
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0056 0.0044 0.0432
Leishmania major carboxylase, putative 0.0682 0.0735 0.375
Loa Loa (eye worm) hypothetical protein 0.0205 0.0208 0.1101
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0526 0.0563 0.0562
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0036 0.0021 0.0174
Echinococcus multilocularis transient receptor potential cation channel 0.0036 0.0021 0.0021
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0036 0.0021 0.0111
Toxoplasma gondii hypothetical protein 0.005 0.0037 0.0184
Loa Loa (eye worm) hypothetical protein 0.005 0.0037 0.0194
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0003
Mycobacterium tuberculosis Conserved protein 0.0086 0.0077 0.0265
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0038 0.0024 0.0289
Trichomonas vaginalis phosphofructokinase, putative 0.0151 0.0149 0.1867
Trypanosoma brucei 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0243 0.025 0.1268
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0044 0.003 0.0146
Schistosoma mansoni short chain dehydrogenase 0.0036 0.0021 0.0088
Leishmania major hypothetical protein, conserved 0.0036 0.0021 0.0107
Leishmania major trypanothione reductase 0.0027 0.0012 0.0059
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0275 0.0285 0.3873
Toxoplasma gondii acetyl-CoA carboxylase ACC1 0.179 0.1958 1
Brugia malayi nuclear hormone receptor 0.008 0.007 0.0367
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.007 0.0058 0.0201
Trichomonas vaginalis ap endonuclease, putative 0.0028 0.0012 0.0143
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0036 0.0022 0.009
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0081 0.0071 0.0356
Leishmania major importin beta-1 subunit, putative 0.0032 0.0017 0.0088
Schistosoma mansoni serine/threonine protein kinase 0.0131 0.0126 0.0531
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0036 0.0021 0.0254
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0036 0.0022 0.0179
Loa Loa (eye worm) pip kinase 2 0.0117 0.0111 0.0585
Plasmodium falciparum lipid/sterol:H+ symporter 0.005 0.0037 0.0264
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0027 0.0012 0.0134
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0056 0.0044 0.036
Entamoeba histolytica hypothetical protein, conserved 0.0036 0.0021 0.018
Entamoeba histolytica hypothetical protein 0.0032 0.0017 0.0137
Trichomonas vaginalis glucosylceramidase, putative 0.0113 0.0106 0.1326
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0194 0.0196 0.0685
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0028 0.0012 0.0318
Echinococcus multilocularis inositol monophosphatase 1 0.0029 0.0014 0.0013
Entamoeba histolytica short chain dehydrogenase family protein 0.0036 0.0021 0.018
Leishmania major dihydrolipoamide acetyltransferase precursor, putative 0.0063 0.0051 0.0259
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0021 0.0111
Toxoplasma gondii AGC kinase 0.0036 0.0022 0.0106
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0081 0.0071 0.0737
Echinococcus granulosus 6 phosphofructokinase 0.0151 0.0149 0.0625
Loa Loa (eye worm) hypothetical protein 0.008 0.007 0.0365
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0048 0.0241
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0036 0.0021 0.0248
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0027 0.0011 0.009
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0027 0.0011 0.001
Loa Loa (eye worm) MH2 domain-containing protein 0.0316 0.033 0.1747
Loa Loa (eye worm) hypothetical protein 0.0017 0.0001 0.0001
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0036 0.0021 0.0254
Loa Loa (eye worm) MBCTL1 0.0077 0.0067 0.0349
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.008 0.007 0.0291
Echinococcus granulosus pyruvate kinase 0.0081 0.0071 0.0298
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0024 0.0289
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0042 0.0028 0.0146
Leishmania major 4-coumarate:coa ligase-like protein 0.0275 0.0285 0.1455
Mycobacterium tuberculosis Probable hydrolase 0.0086 0.0077 0.0265
Brugia malayi nuclear receptor RXR 0.0038 0.0023 0.0121
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0041 0.0027 0.0131
Echinococcus multilocularis nibrin 0.0056 0.0044 0.0043
Plasmodium vivax acyl-CoA synthetase, putative 0.0205 0.0208 0.1476
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0036 0.0021 0.0174
Mycobacterium ulcerans pyruvate carboxylase 0.0682 0.0735 1
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0036 0.0021 0.0102
Entamoeba histolytica hypothetical protein 0.0036 0.0021 0.018
Schistosoma mansoni lamin 0.0022 0.0006 0.0022
Echinococcus granulosus nibrin 0.0056 0.0044 0.0182
Loa Loa (eye worm) hypothetical protein 0.008 0.007 0.0365
Loa Loa (eye worm) patched family protein 0.005 0.0037 0.0194
Onchocerca volvulus 0.0096 0.0087 0.1086
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0081 0.0071 0.0356
Schistosoma mansoni steroid dehydrogenase 0.0036 0.0021 0.0088
Echinococcus multilocularis nuclear receptor nhr 48 0.0038 0.0023 0.0023
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0027 0.0012 0.0011
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0045 0.0032 0.0031
Leishmania major DNA polymerase kappa, putative 0.0061 0.0048 0.0246
Brugia malayi Patched family protein 0.005 0.0037 0.0195
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0184 0.0185 0.0943
Loa Loa (eye worm) hypothetical protein 0.0036 0.0021 0.0109
Entamoeba histolytica phosphofructokinase, putative 0.0151 0.0149 0.1606
Loa Loa (eye worm) oxidoreductase 0.0081 0.0071 0.0372
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0229 0.0234 0.0819
Trypanosoma cruzi 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0243 0.025 0.2068
Loa Loa (eye worm) hypothetical protein 0.0086 0.0077 0.0403
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0045 0.0031 0.0381
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0028 0.0135
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0045 0.0031 0.0031
Chlamydia trachomatis DNA ligase 0.0056 0.0044 0.0265
Echinococcus multilocularis carbonyl reductase 1 0.0036 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0038 0.0023 0.012
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0062 0.005 0.0173
Schistosoma mansoni membrane associated proteins in eicosanoid and glutathione metabolism family member 0.0212 0.0216 0.091
Schistosoma mansoni jumonji domain containing protein 0.005 0.0037 0.0154
Schistosoma mansoni zinc finger protein 0.0038 0.0023 0.0096
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0036 0.0021 0.0088
Loa Loa (eye worm) pyruvate kinase 0.0081 0.0071 0.0375
Trichomonas vaginalis phosphofructokinase, putative 0.0041 0.0027 0.0324
Mycobacterium ulcerans short chain dehydrogenase 0.0036 0.0021 0.0273
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.008 0.007 0.0367
Schistosoma mansoni propionyl-CoA carboxylase beta chain mitochondrial precursor 0.0243 0.025 0.1052
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0036 0.0021 0.0087
Echinococcus multilocularis FTZ F1 alpha 0.008 0.007 0.0069
Leishmania major pyruvate kinase 0.0081 0.0071 0.0363
Plasmodium vivax acetyl-CoA synthetase, putative 0.0081 0.0071 0.0501
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0086 0.0077 0.0403
Loa Loa (eye worm) nuclear receptor NHR-67 0.0038 0.0023 0.012
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0091 0.0083 0.0416
Echinococcus multilocularis zinc finger protein 0.0023 0.0007 0.0007
Schistosoma mansoni hypothetical protein 0.0182 0.0183 0.0769
Schistosoma mansoni coup transcription factor 0.008 0.007 0.0292
Schistosoma mansoni DNA polymerase eta 0.0061 0.0048 0.0203
Echinococcus granulosus thioredoxin glutathione reductase 0.0028 0.0012 0.0049
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0076 0.0065 0.0814
Wolbachia endosymbiont of Brugia malayi branched-chain alpha-keto acid dehydrogenase subunit E2 0.0063 0.0051 0.0532
Giardia lamblia Pyruvate kinase 0.0042 0.0028 0.0799
Leishmania major 3-keto-dihydrosphingosine reductase 0.0036 0.0021 0.0107
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0275 0.0285 0.0998
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0081 0.0071 0.0373
Loa Loa (eye worm) transcription factor SMAD2 0.0316 0.033 0.1747
Echinococcus granulosus TGF beta signal transducer SmadC 0.0022 0.0005 0.002
Loa Loa (eye worm) hypothetical protein 0.0056 0.0044 0.0229
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0026 0.001 0.0098
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0027 0.0011 0.0044
Schistosoma mansoni ran 0.0029 0.0014 0.0058
Toxoplasma gondii isocitrate dehydrogenase 0.0034 0.002 0.0094
Brugia malayi ImpB/MucB/SamB family protein 0.0061 0.0048 0.0255
Schistosoma mansoni short chain dehydrogenase 0.0036 0.0021 0.0088
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0036 0.0021 0.0273
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0036 0.0021 0.0254
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0024 0.0008 0.0042
Toxoplasma gondii 6-phosphofructokinase 0.0041 0.0027 0.0131
Echinococcus granulosus retinol dehydrogenase 11 0.0036 0.0021 0.0087
Plasmodium vivax 6-phosphofructokinase, putative 0.0041 0.0027 0.019
Leishmania major propionyl-coa carboxylase beta chain, putative 0.0243 0.025 0.1273
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.008 0.007 0.0367
Mycobacterium ulcerans short chain dehydrogenase 0.0036 0.0021 0.0273
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0081 0.0071 0.0949
Leishmania major hypothetical protein, conserved 0.0036 0.0021 0.0107
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0028 0.0012 0.0082
Echinococcus multilocularis oxidoreductase 0.0036 0.0021 0.0021
Trypanosoma brucei dihydrolipoamide branched chain transacylase, putative 0.0063 0.0051 0.0253
Trypanosoma brucei unspecified product 0.0042 0.0028 0.0135
Mycobacterium ulcerans carveol-like dehydrogenase 0.0036 0.0021 0.0273
Leishmania major DNA polymerase eta, putative 0.0061 0.0048 0.0246
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0027 0.0011 0.0044
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0027 0.0012 0.0061
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0034 0.002 0.0138
Mycobacterium ulcerans short chain dehydrogenase 0.0036 0.0021 0.0273
Brugia malayi phosphofructokinase 0.0151 0.0149 0.0785
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0036 0.0021 0.0212
Echinococcus granulosus metabotropic glutamate receptor 5 0.0043 0.0029 0.0119
Echinococcus granulosus GPCR family 2 0.0182 0.0183 0.0768
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0036 0.0021 0.018
Loa Loa (eye worm) dehydrogenase 0.0036 0.0021 0.0109
Trypanosoma brucei trypanothione reductase 0.0027 0.0012 0.0054
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0272 0.0282 0.0281
Brugia malayi Dehydrogenases, short chain protein 30 0.0036 0.0021 0.0111
Loa Loa (eye worm) hypothetical protein 0.0038 0.0023 0.012
Onchocerca volvulus 0.0038 0.0023 0.0273
Plasmodium falciparum replication factor C subunit 1, putative 0.0056 0.0044 0.031
Leishmania major acetyl-CoA synthetase, putative 0.0081 0.0071 0.036
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0038 0.0023 0.0121
Schistosoma mansoni Replicative DNA helicase 0.0296 0.0309 0.1301
Trypanosoma cruzi DNA repair protein, putative 0.0025 0.001 0.0079
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0151 0.0149 0.4598
Schistosoma mansoni serine/threonine protein kinase 0.0036 0.0022 0.0091
Loa Loa (eye worm) hypothetical protein 0.083 0.0898 0.4752
Trichomonas vaginalis glucosylceramidase, putative 0.0107 0.01 0.1246
Echinococcus granulosus snurportin 1 0.0427 0.0453 0.1909
Onchocerca volvulus 0.0117 0.011 0.1378
Mycobacterium ulcerans short-chain dehydrogenase 0.0036 0.0021 0.0273
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0044 0.003 0.0146
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0035 0.0433
Brugia malayi dihydrolipoamide S-acetyltransferase precursor, putative 0.0063 0.0051 0.0268
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0036 0.0022 0.0179
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0038 0.0024 0.0289
Plasmodium falciparum steroid dehydrogenase, putative 0.0036 0.0021 0.015
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0027 0.0012 0.0054
Loa Loa (eye worm) hypothetical protein 0.0063 0.0051 0.0267
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0002 0.0018
Leishmania major DNA damage repair protein, putative 0.0019 0.0002 0.0011
Trypanosoma cruzi acetyl-CoA carboxylase, putative 0.0243 0.025 0.2068
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0027 0.0012 0.0134
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0262 0.0271 0.1433
Echinococcus granulosus tar DNA binding protein 0.0272 0.0282 0.1187
Echinococcus multilocularis 6 phosphofructokinase 0.0151 0.0149 0.0148
Mycobacterium tuberculosis Probable oxidoreductase 0.0036 0.0021 0.007
Brugia malayi Patched family protein 0.005 0.0037 0.0195
Mycobacterium ulcerans short chain dehydrogenase 0.0036 0.0021 0.0273
Mycobacterium ulcerans acetyl-coenzyme a carboxylase carboxyl transferase (subunit beta) AccD3 0.0243 0.025 0.3386
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0275 0.0285 0.3009
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0044 0.0539
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.002 0.016
Echinococcus multilocularis carbonyl reductase 1 0.0036 0.0021 0.0021
Loa Loa (eye worm) patched family protein 0.005 0.0037 0.0194
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0036 0.0021 0.0021
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0076 0.0065 0.0814
Loa Loa (eye worm) nuclear hormone receptor 0.0038 0.0023 0.012
Echinococcus granulosus survival motor neuron protein 1 0.1009 0.1096 0.4623
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0021 0.0111
Brugia malayi ecdysone receptor 0.0038 0.0023 0.0121
Mycobacterium ulcerans acyl-CoA synthetase 0.0275 0.0285 0.3873
Loa Loa (eye worm) hypothetical protein 0.005 0.0037 0.0194
Loa Loa (eye worm) hypothetical protein 0.005 0.0037 0.0194
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0058 0.0046 0.0567
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0125 0.0119 0.1491
Trypanosoma brucei hypothetical protein, conserved 0.0027 0.0012 0.0054
Brugia malayi ImpB/MucB/SamB family protein 0.0061 0.0048 0.0255
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0034 0.002 0.0081
Schistosoma mansoni patched 1 0.0356 0.0375 0.1581
Schistosoma mansoni transcription factor LCR-F1 0.0301 0.0314 0.1323
Toxoplasma gondii AGC kinase 0.0036 0.0022 0.0106
Plasmodium vivax carbamoyl phosphate synthetase, putative 0.0154 0.0152 0.1075
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0021 0.0111
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0038 0.0024 0.0289
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0036 0.0021 0.0102
Echinococcus multilocularis PHD finger protein rhinoceros 0.0019 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0027 0.0012 0.0059
Plasmodium falciparum lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex 0.0063 0.0051 0.0361
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0068 0.0056 0.0692
Leishmania major hypothetical protein, conserved 0.0086 0.0077 0.039
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0081 0.0071 0.0585
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0036 0.0021 0.0273
Mycobacterium ulcerans short chain dehydrogenase 0.0036 0.0021 0.0273
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0262 0.0271 0.1142
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0081 0.0071 0.0949
Loa Loa (eye worm) hypothetical protein 0.0275 0.0285 0.1507
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0027 0.0012 0.0053
Echinococcus multilocularis pyruvate kinase 0.0064 0.0052 0.0052
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0081 0.0071 0.0949
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0036 0.0021 0.007
Echinococcus multilocularis beta LACTamase domain containing family member 0.0086 0.0077 0.0076
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0036 0.0021 0.007
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0002 0.0006
Loa Loa (eye worm) hypothetical protein 0.005 0.0037 0.0194
Mycobacterium ulcerans recombinase A 0.0083 0.0073 0.0978
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0051 0.0038 0.0158
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0036 0.0021 0.0174
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0036 0.0021 0.0087
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0027 0.0011 0.0275
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0027 0.0012 0.0011
Trichomonas vaginalis set domain proteins, putative 0.0733 0.0791 1
Schistosoma mansoni hypothetical protein 0.0182 0.0183 0.0769
Entamoeba histolytica acyl-CoA synthetase, putative 0.0275 0.0285 0.3137
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0038 0.0023 0.0023
Loa Loa (eye worm) oxidoreductase 0.0036 0.0021 0.0109
Schistosoma mansoni dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase 0.0063 0.0051 0.0213
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0086 0.0077 0.0265
Onchocerca volvulus 0.0081 0.0071 0.0877
Mycobacterium ulcerans short chain dehydrogenase 0.0036 0.0021 0.0273
Echinococcus granulosus dnaJ subfamily B 0.2163 0.2369 1
Entamoeba histolytica short chain dehydrogenase family protein 0.0036 0.0021 0.018
Trypanosoma brucei short-chain dehydrogenase, putative 0.0036 0.0021 0.0102
Trichomonas vaginalis phosphofructokinase, putative 0.0041 0.0027 0.0324
Plasmodium vivax pyruvate kinase 2, putative 0.0042 0.0028 0.0196
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0036 0.0021 0.0174
Onchocerca volvulus 0.0036 0.0021 0.0248
Plasmodium vivax importin-beta 2, putative 0.004 0.0026 0.0183
Brugia malayi Nuclear hormone receptor-like 1 0.0042 0.0028 0.0147
Plasmodium falciparum dihydrolipoamide acyltransferase component E2 0.0063 0.0051 0.0361
Loa Loa (eye worm) Smad1 0.0022 0.0005 0.0026
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0081 0.0071 0.0245
Loa Loa (eye worm) hypothetical protein 0.005 0.0037 0.0194
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0021 0.0111
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0027 0.0011 0.0057
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0048 0.0241
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0012 0.0095
Toxoplasma gondii pyruvate carboxylase 0.0682 0.0735 0.3747
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0041 0.0027 0.077
Mycobacterium ulcerans short chain dehydrogenase 0.0036 0.0021 0.0273
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.008 0.007 0.0069
Trypanosoma cruzi importin beta-1 subunit, putative 0.0032 0.0017 0.0143
Giardia lamblia PHD finger protein 15 0.0019 0.0003 0.0015
Trichomonas vaginalis glucosylceramidase, putative 0.0107 0.01 0.1246
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0272 0.0282 0.1186
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0081 0.0071 0.0245
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0025 0.001 0.0039
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0044 0.003 0.0146
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0029 0.0014 0.0072
Trichomonas vaginalis glucosylceramidase, putative 0.0163 0.0161 0.2028
Brugia malayi MH1 domain containing protein 0.0022 0.0005 0.0027
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0036 0.0021 0.0086
Mycobacterium ulcerans short-chain dehydrogenase 0.0036 0.0021 0.0273
Loa Loa (eye worm) hypothetical protein 0.0036 0.0022 0.0113
Loa Loa (eye worm) hypothetical protein 0.005 0.0037 0.0194
Toxoplasma gondii biotin-requiring enzyme domain-containing protein 0.0063 0.0051 0.0254
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0081 0.0071 0.0372
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0036 0.0021 0.0174
Trichomonas vaginalis penicillin-binding protein, putative 0.0086 0.0077 0.0956
Loa Loa (eye worm) hypothetical protein 0.0036 0.0021 0.0109
Echinococcus granulosus microsomal glutathione S transferase 3 0.0049 0.0035 0.0147
Mycobacterium ulcerans acyl-CoA synthetase 0.0081 0.0071 0.0949
Trypanosoma brucei 3-methylcrotonyl-CoA carboxylase alpha subunit, putative 0.0682 0.0735 0.3747
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.008 0.007 0.0292
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0021 0.0174
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0044 0.003 0.0146
Brugia malayi protein C24B5.3 0.005 0.0037 0.0195
Plasmodium vivax glutathione reductase, putative 0.0027 0.0012 0.0083
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.002 0.0098
Echinococcus granulosus WW domain containing oxidoreductase 0.0036 0.0021 0.0087
Loa Loa (eye worm) hypothetical protein 0.005 0.0037 0.0194
Toxoplasma gondii ABC1 family protein 0.0086 0.0077 0.0386
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0035 0.0433
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0036 0.0021 0.007
Echinococcus multilocularis thioredoxin glutathione reductase 0.0028 0.0012 0.0012
Brugia malayi nuclear receptor NHR-88 0.008 0.007 0.0367
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0091 0.0083 0.0684
Entamoeba histolytica hypothetical protein 0.0056 0.0044 0.0431
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0184 0.0185 0.1532
Loa Loa (eye worm) hypothetical protein 0.005 0.0037 0.0194
Plasmodium falciparum phosphodiesterase gamma, putative 0.0027 0.0012 0.0083
Mycobacterium ulcerans short chain dehydrogenase 0.0036 0.0021 0.0273
Echinococcus granulosus carbonyl reductase 1 0.0036 0.0021 0.0087
Brugia malayi nuclear hormone receptor family member odr-7 0.0038 0.0023 0.0121
Loa Loa (eye worm) hypothetical protein 0.0077 0.0067 0.0349
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0048 0.0241
Mycobacterium tuberculosis Acetyl/propionyl-CoA carboxylase (beta subunit) AccD6 0.0243 0.025 0.0872
Leishmania major quinonoid dihydropteridine reductase 0.0036 0.0021 0.0107
Loa Loa (eye worm) hypothetical protein 0.0038 0.0023 0.012
Echinococcus multilocularis rho associated protein kinase 0.0131 0.0126 0.0126
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0027 0.0012 0.0047
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0021 0.0102
Mycobacterium tuberculosis Conserved hypothetical protein 0.0061 0.0048 0.0166
Loa Loa (eye worm) pyruvate kinase 0.0081 0.0071 0.0375
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0076 0.0065 0.0541
Mycobacterium tuberculosis Probable propionyl-CoA carboxylase beta chain 5 AccD5 (pccase) (propanoyl-CoA:carbon dioxide ligase) 0.0243 0.025 0.0872
Loa Loa (eye worm) patched family protein 0.005 0.0037 0.0194
Loa Loa (eye worm) hypothetical protein 0.008 0.007 0.0365
Loa Loa (eye worm) hypothetical protein 0.005 0.0037 0.0194
Leishmania major oxidoreductase-like protein 0.0036 0.0021 0.0107
Trichomonas vaginalis phosphofructokinase, putative 0.0151 0.0149 0.1867
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0036 0.0021 0.0174
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0021 0.0111
Echinococcus multilocularis Niemann Pick C1 protein 0.083 0.0898 0.0897
Trichomonas vaginalis glucosylceramidase, putative 0.0107 0.01 0.1246
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0096 0.0087 0.0367
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0027 0.0012 0.0083
Giardia lamblia Hypothetical protein 0.0036 0.0021 0.0595
Schistosoma mansoni dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase 0.0063 0.0051 0.0213
Trypanosoma cruzi hypothetical protein, conserved 0.0086 0.0077 0.0634
Mycobacterium tuberculosis Probable dehydrogenase 0.0036 0.0021 0.007
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0081 0.0071 0.0737
Brugia malayi hypothetical protein 0.0103 0.0096 0.0505
Toxoplasma gondii dihydrolipoamide acyltransferase, putative 0.0063 0.0051 0.0254
Echinococcus granulosus pyruvate kinase 0.0042 0.0028 0.0114
Mycobacterium tuberculosis Probable oxidoreductase 0.0036 0.0021 0.007
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0041 0.0027 0.0324
Schistosoma mansoni hypothetical protein 0.0393 0.0416 0.1753
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0029 0.0014 0.016
Trichomonas vaginalis steroid dehydrogenase, putative 0.0036 0.0021 0.0254
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0029 0.0014 0.01
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0024
Mycobacterium ulcerans acyl-CoA synthetase 0.0081 0.0071 0.0949
Entamoeba histolytica deoxycytidyl transferase, putative 0.0061 0.0048 0.0485
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0081 0.0071 0.0373
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0086 0.0077 0.0265
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0184 0.0185 0.0939
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0036 0.0021 0.0107
Mycobacterium tuberculosis Probable pyruvate carboxylase Pca (pyruvic carboxylase) 0.0682 0.0735 0.2576
Mycobacterium ulcerans short chain dehydrogenase 0.0036 0.0021 0.0273
Loa Loa (eye worm) hypothetical protein 0.005 0.0037 0.0194
Loa Loa (eye worm) hypothetical protein 0.0027 0.0011 0.0056
Schistosoma mansoni short chain dehydrogenase 0.0036 0.0021 0.0088
Mycobacterium ulcerans acyl-CoA synthetase 0.0081 0.0071 0.0949
Plasmodium falciparum GAF domain-related protein, putative 0.0018 0.0001 0.0008
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0275 0.0285 0.3873
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0012 0.0134
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0036 0.0021 0.007
Entamoeba histolytica hypothetical protein 0.0301 0.0314 0.3455
Chlamydia trachomatis acetyl-coenzyme A carboxylase carboxyl transferase subunit beta 0.0243 0.025 0.3488
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0076 0.0065 0.0814
Brugia malayi hypothetical protein 0.0042 0.0028 0.0147
Echinococcus multilocularis acetyl coenzyme A carboxylase 1 0.179 0.1958 0.1958
Brugia malayi Nuclear hormone receptor family member nhr-14 0.008 0.007 0.0367
Trichomonas vaginalis glucosylceramidase, putative 0.0107 0.01 0.1246
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0021 0.0102
Loa Loa (eye worm) intermediate filament protein 0.0022 0.0006 0.0026
Loa Loa (eye worm) hypothetical protein 0.0042 0.0028 0.0146
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0077 0.0067 0.035
Echinococcus multilocularis pyruvate kinase 0.0042 0.0028 0.0027
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0027 0.0012 0.0061
Echinococcus granulosus Smad4 0.0022 0.0005 0.002
Onchocerca volvulus 0.0038 0.0023 0.0273
Brugia malayi Calcitonin receptor-like protein seb-1 0.0575 0.0617 0.3263
Onchocerca volvulus 0.005 0.0037 0.0451
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0076 0.0065 0.0814
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0184 0.0185 0.1309
Loa Loa (eye worm) hypothetical protein 0.005 0.0037 0.0194
Echinococcus granulosus peregrin 0.0021 0.0005 0.0017
Schistosoma mansoni short chain dehydrogenase 0.0036 0.0021 0.0088
Echinococcus granulosus retinoic acid receptor rxr beta a 0.008 0.007 0.0291
Loa Loa (eye worm) patched family protein 0.005 0.0037 0.0194
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0027 0.0012 0.0134
Echinococcus granulosus microtubule associated protein 2 0.17 0.1858 0.7842
Plasmodium vivax phosphodiesterase gamma, putative 0.0027 0.0012 0.0083
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0045 0.0031 0.0131
Onchocerca volvulus 0.0022 0.0006 0.0049
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0027 0.0012 0.0296
Brugia malayi Bromodomain containing protein 0.0062 0.005 0.0262
Brugia malayi F/Y-rich N-terminus family protein 0.0063 0.0051 0.0268
Trypanosoma brucei importin beta-1 subunit, putative 0.004 0.0026 0.0125
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0406 0.043 0.2273
Trichomonas vaginalis phosphofructokinase, putative 0.0041 0.0027 0.0324
Trypanosoma brucei 2-oxoglutarate dehydrogenase E2 component, putative 0.0063 0.0051 0.0253
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0027 0.0012 0.0095
Onchocerca volvulus Huntingtin homolog 0.0118 0.0112 0.14
Onchocerca volvulus 0.0081 0.0071 0.0877
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0019 0.0002 0.0006
Mycobacterium tuberculosis Conserved hypothetical protein 0.0102 0.0094 0.0326
Echinococcus granulosus nuclear receptor 2DBD gamma 0.008 0.007 0.0291
Loa Loa (eye worm) latrophilin receptor protein 2 0.0182 0.0183 0.0964
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0026
Loa Loa (eye worm) hypothetical protein 0.005 0.0037 0.0194
Leishmania major hypothetical protein, conserved 0.0027 0.0012 0.0059
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0036 0.0021 0.0087
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0301 0.0314 0.1322
Mycobacterium leprae Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex SucB 0.0063 0.0051 0.0527
Trypanosoma brucei dihydrolipoamide acetyltransferase E2 subunit, putative 0.0063 0.0051 0.0253
Treponema pallidum replicative DNA helicase (dnaB) 0.0296 0.0309 1
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0027 0.0012 0.0011
Mycobacterium ulcerans short chain dehydrogenase 0.0036 0.0021 0.0273
Trypanosoma cruzi short chain dehydrogenase, putative 0.0036 0.0021 0.0174
Onchocerca volvulus 0.0036 0.0021 0.0248
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0038 0.0023 0.0095
Brugia malayi nuclear receptor NHR-88 0.0038 0.0023 0.0121
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0042 0.0028 0.0117
Schistosoma mansoni carbonyl reductase 0.0036 0.0021 0.0088
Schistosoma mansoni methylcrotonyl-CoA carboxylase 0.0682 0.0735 0.3099
Brugia malayi pyruvate kinase 0.0017 0.0001 0.0001
Mycobacterium tuberculosis Probable oxidoreductase 0.0069 0.0058 0.02
Onchocerca volvulus Sepiapterin reductase homolog 0.0036 0.0021 0.0248
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0021 0.015
Echinococcus multilocularis pyruvate kinase 0.0081 0.0071 0.0071
Leishmania major cathepsin L-like protease 0.0044 0.003 0.0151
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0029 0.0014 0.0069
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0058 0.0046 0.0379
Brugia malayi hypothetical protein 0.0036 0.0021 0.0111
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0024 0.0289
Trypanosoma brucei chrX additional, unordered contigs 0.0019 0.0002 0.0006
Toxoplasma gondii pyruvate kinase PyKII 0.0042 0.0028 0.0135
Loa Loa (eye worm) hypothetical protein 0.0096 0.0087 0.046
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0027 0.0012 0.0054
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0027 0.0011 0.0055
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0036 0.0021 0.0254
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0644 0.0693 0.3667
Trypanosoma brucei short-chain dehydrogenase, putative 0.0036 0.0021 0.0102
Leishmania major cathepsin L-like protease 0.0044 0.003 0.0151
Echinococcus multilocularis musashi 0.0022 0.0006 0.0005
Trypanosoma cruzi hypothetical protein, conserved 0.0086 0.0077 0.0634
Toxoplasma gondii thioredoxin reductase 0.0027 0.0012 0.0054
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0036 0.0022 0.0105
Loa Loa (eye worm) hypothetical protein 0.005 0.0037 0.0194
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0081 0.0071 0.0245
Chlamydia trachomatis dihydrolipoamide succinyltransferase 0.0063 0.0051 0.0378
Mycobacterium tuberculosis Possible oxidoreductase 0.0036 0.0021 0.007
Echinococcus multilocularis dihydrolipoyllysine residue acetyltransferase 0.0063 0.0051 0.005
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0036 0.0022 0.0106
Brugia malayi Patched family protein 0.005 0.0037 0.0195
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0081 0.0071 0.0585
Mycobacterium tuberculosis Biotinylated protein TB7.3 0.0063 0.0051 0.0175
Onchocerca volvulus Pyruvate kinase homolog 0.0081 0.0071 0.0883
Schistosoma mansoni dihydrolipoamide S-acetyltransferase 0.0063 0.0051 0.0213
Echinococcus granulosus replication factor c subunit 1 0.0056 0.0044 0.0182
Loa Loa (eye worm) hypothetical protein 0.0086 0.0077 0.0403
Leishmania major quinonoid dihydropteridine reductase 0.0036 0.0021 0.0107
Trypanosoma cruzi hypothetical protein, conserved 0.0056 0.0044 0.036
Schistosoma mansoni topbp1 0.0056 0.0044 0.0183
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0044 0.0539
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.0036 0.0021 0.0212
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.008 0.007 0.0069
Brugia malayi isocitrate dehydrogenase 0.0034 0.002 0.0102
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0086 0.0077 0.0322
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.008 0.007 0.0291
Trypanosoma brucei DNA polymerase IV, putative 0.0061 0.0048 0.0241
Brugia malayi Patched protein homolog 1 0.005 0.0037 0.0195
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0051 0.0038 0.0037
Schistosoma mansoni steroid dehydrogenase 0.0036 0.0021 0.0088
Loa Loa (eye worm) hypothetical protein 0.0038 0.0023 0.012
Echinococcus multilocularis retinol dehydrogenase 13 0.0036 0.0021 0.0021
Onchocerca volvulus 0.0036 0.0021 0.0248
Trypanosoma cruzi trypanothione reductase, putative 0.0027 0.0012 0.0095
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0038 0.0023 0.0273
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0036 0.0022 0.009
Leishmania major dihydrolipoamide acetyltransferase precursorlike protein 0.0063 0.0051 0.0259
Plasmodium falciparum biotin carboxylase subunit of acetyl CoA carboxylase, putative 0.1296 0.1412 1
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0036 0.0021 0.0174
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0056 0.0044 0.0217
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0027 0.0012 0.0054
Brugia malayi nuclear hormone receptor 0.0038 0.0023 0.0121
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0036 0.0021 0.0273
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.0025 0.0009 0.0045
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0081 0.0071 0.0296
Loa Loa (eye worm) hypothetical protein 0.005 0.0037 0.0194
Toxoplasma gondii aldehyde dehydrogenase 0.0229 0.0234 0.1191
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0021 0.0111
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0363 0.0382 0.1611
Brugia malayi Nuclear hormone receptor family member nhr-25 0.008 0.007 0.0367
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0012 0.0095
Trichomonas vaginalis D-aminoacylase, putative 0.0086 0.0077 0.0956
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0096 0.0087 0.0087
Brugia malayi Pyruvate kinase, muscle isozyme 0.0081 0.0071 0.0376
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0036 0.0021 0.007
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0024 0.0008 0.0027
Chlamydia trachomatis recombinase RecA 0.0083 0.0073 0.0723
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0038 0.0023 0.0095
Echinococcus multilocularis microtubule associated protein 2 0.17 0.1858 0.1858
Loa Loa (eye worm) hypothetical protein 0.0056 0.0044 0.0229
Loa Loa (eye worm) glutathione reductase 0.0027 0.0012 0.0059
Loa Loa (eye worm) hypothetical protein 0.0107 0.01 0.0528
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0069 0.0058 0.02
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0033 0.0018 0.0149
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0036 0.0021 0.0111
Brugia malayi intermediate filament protein 0.0022 0.0006 0.0027
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0056 0.0044 0.0539
Trypanosoma brucei oxidoreductase-like protein 0.0036 0.0021 0.0102
Mycobacterium tuberculosis Probable lipase LipE 0.0086 0.0077 0.0265
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0036 0.0021 0.0254
Brugia malayi Pre-SET motif family protein 0.0644 0.0693 0.3668
Trypanosoma cruzi 3-methylcrotonyl-CoA carboxylase, putative 0.0682 0.0735 0.6093
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0069 0.0058 0.02
Mycobacterium tuberculosis Probable oxidoreductase 0.0036 0.0021 0.007
Loa Loa (eye worm) hypothetical protein 0.0036 0.0021 0.0109
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0184 0.0185 0.1532
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0076 0.0065 0.0814
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0034 0.002 0.008
Plasmodium vivax replication factor C subunit 1, putative 0.0056 0.0044 0.031
Brugia malayi PHD-finger family protein 0.0027 0.0011 0.0059
Toxoplasma gondii ATPase, AAA family protein 0.0056 0.0044 0.0217
Plasmodium vivax pyruvate kinase, putative 0.0081 0.0071 0.0505
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0081 0.0071 0.0245
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0021 0.0111
Mycobacterium leprae Conserved hypothetical protein 0.0873 0.0945 1
Schistosoma mansoni short chain dehydrogenase 0.0036 0.0021 0.0088
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0048 0.0241
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0002 0.0018
Entamoeba histolytica hypothetical protein 0.0301 0.0314 0.3455
Brugia malayi Pip kinase protein 2 0.0117 0.0111 0.0586
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0036 0.0021 0.0121
Mycobacterium ulcerans carbamoyl phosphate synthase large subunit 0.0154 0.0152 0.2054
Trypanosoma cruzi 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0243 0.025 0.2068
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0048 0.0241
Brugia malayi Latrophilin receptor protein 2 0.0182 0.0183 0.0965
Onchocerca volvulus 0.0036 0.0021 0.0248
Onchocerca volvulus 0.0022 0.0006 0.0049
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0048 0.0241
Entamoeba histolytica hypothetical protein 0.0301 0.0314 0.3455
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0262 0.0271 0.1143
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0036 0.0021 0.007
Mycobacterium leprae Probable oxidoreductase 0.0036 0.0021 0.0212
Brugia malayi CXXC zinc finger family protein 0.0169 0.0169 0.0891
Echinococcus multilocularis peregrin 0.0021 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.005 0.0037 0.0194
Loa Loa (eye worm) hypothetical protein 0.0205 0.0208 0.1101
Brugia malayi beta-lactamase family protein 0.0086 0.0077 0.0404
Echinococcus multilocularis GPCR, family 2 0.0182 0.0183 0.0182
Trypanosoma brucei short-chain dehydrogenase, putative 0.0036 0.0021 0.0102
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0095 0.0087 0.0364
Echinococcus multilocularis conserved hypothetical protein 0.0036 0.0021 0.0021
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0028 0.0012 0.0062
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.008 0.007 0.0069
Mycobacterium ulcerans dehydrogenase 0.0036 0.0021 0.0273
Brugia malayi hypothetical protein 0.0301 0.0314 0.1659
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0034 0.002 0.0019
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0031 0.0016 0.0085
Trypanosoma brucei recA bacterial DNA recombination protein, putative 0.0025 0.001 0.0043
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0027 0.0011 0.0066
Echinococcus multilocularis snurportin 1 0.0427 0.0453 0.0452
Onchocerca volvulus Protein patched homolog 0.005 0.0037 0.0451
Schistosoma mansoni jumonji/arid domain-containing protein 0.0034 0.0019 0.0081
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0427 0.0453 0.2395
Trichomonas vaginalis glucosylceramidase, putative 0.0163 0.0161 0.2028
Echinococcus multilocularis microsomal glutathione S transferase 3 0.0049 0.0035 0.0035
Brugia malayi hypothetical protein 0.005 0.0037 0.0195
Trichomonas vaginalis replication factor C large subunit, putative 0.0056 0.0044 0.0539
Toxoplasma gondii oxidoreductase, putative 0.0036 0.0021 0.0102
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0036 0.0021 0.0087
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0027 0.0012 0.0054
Brugia malayi Nuclear hormone receptor family member nhr-49 0.008 0.007 0.0367
Brugia malayi Patched family protein 0.005 0.0037 0.0195
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0028 0.0012 0.004
Echinococcus granulosus Protein patched homolog 1 0.0356 0.0375 0.158
Trypanosoma cruzi ISWI complex protein 0.0018 0.0001 0.0008
Trichomonas vaginalis D-aminoacylase, putative 0.0086 0.0077 0.0956
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0076 0.0065 0.0328
Schistosoma mansoni hypothetical protein 0.2163 0.2369 1
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0117 0.0111 0.0467
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0044 0.003 0.0146
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0061 0.0048 0.0254
Trichomonas vaginalis pyruvate kinase, putative 0.0081 0.0071 0.0888
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.0025 0.0132
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0024 0.0008 0.0032
Echinococcus granulosus beta LACTamase domain containing family member 0.0086 0.0077 0.0321
Schistosoma mansoni pyruvate kinase 0.0042 0.0028 0.0115
Brugia malayi Nuclear hormone receptor family member nhr-41 0.008 0.007 0.0367
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0034 0.002 0.0064
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0034 0.002 0.0138
Brugia malayi SET domain containing protein 0.0018 0.0002 0.0007
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0021 0.0111
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0061 0.0048 0.0203
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0061 0.0048 0.0048
Leishmania major short chain dehydrogenase/reductase, putative 0.0036 0.0021 0.0107
Plasmodium vivax biotin carboxylase subunit of acetyl CoA carboxylase, putative 0.1296 0.1412 1
Schistosoma mansoni short chain dehydrogenase 0.0036 0.0021 0.0088
Loa Loa (eye worm) hypothetical protein 0.0081 0.0071 0.0372
Trypanosoma cruzi dihydrolipoamide branched chain transacylase, putative 0.0063 0.0051 0.042
Plasmodium falciparum phd finger protein, putative 0.0019 0.0003 0.002
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0076 0.0065 0.0814
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0027 0.0012 0.0048
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0027 0.0012 0.0054
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0081 0.0071 0.036
Brugia malayi Nuclear hormone receptor E75 0.0038 0.0023 0.0121
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0062 0.005 0.0173
Leishmania major short chain dehydrogenase/reductase, putative 0.0036 0.0021 0.0107
Plasmodium falciparum importin beta, putative 0.004 0.0026 0.0183
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0076 0.0065 0.0814
Plasmodium falciparum zinc finger protein, putative 0.0021 0.0005 0.0037
Trichomonas vaginalis DNA polymerase eta, putative 0.0061 0.0048 0.0599
Echinococcus granulosus dna polymerase kappa 0.0061 0.0048 0.0202
Schistosoma mansoni dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase 0.0063 0.0051 0.0213
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0029 0.0014 0.0112
Loa Loa (eye worm) inositol-1 0.0029 0.0014 0.007
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0027 0.0012 0.0048
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0045 0.0032 0.0132
Schistosoma mansoni nuclear hormone receptor 0.0038 0.0023 0.0096
Loa Loa (eye worm) hypothetical protein 0.005 0.0037 0.0194
Loa Loa (eye worm) hypothetical protein 0.0676 0.0728 0.3852
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0027 0.0012 0.0047
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0024 0.0289
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0025 0.001 0.0009
Echinococcus granulosus intermediate filament protein 0.0022 0.0006 0.0021
Loa Loa (eye worm) hypothetical protein 0.005 0.0037 0.0194
Loa Loa (eye worm) hypothetical protein 0.0042 0.0028 0.0146
Brugia malayi Nuclear hormone receptor-like 1 0.008 0.007 0.0367
Plasmodium vivax thioredoxin reductase, putative 0.0027 0.0012 0.0083
Brugia malayi Protein kinase domain containing protein 0.0406 0.043 0.2274
Toxoplasma gondii exonuclease III APE 0.0028 0.0012 0.0058
Brugia malayi Retinol dehydrogenase 12 0.0036 0.0021 0.0111
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0021 0.0111
Mycobacterium ulcerans acetyl-/propionyl-CoA carboxylase subunit beta 0.0243 0.025 0.3386
Echinococcus granulosus lamin 0.0022 0.0006 0.0021
Mycobacterium ulcerans esterase/lipase LipP 0.0086 0.0077 0.1029
Trypanosoma brucei DNA polymerase eta, putative 0.0061 0.0048 0.0241
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0205 0.0208 0.2846
Mycobacterium ulcerans acyl-CoA synthetase 0.0081 0.0071 0.0949
Trichomonas vaginalis conserved hypothetical protein 0.0356 0.0375 0.4733
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0081 0.0071 0.0372
Brugia malayi 6-phosphofructokinase 0.0151 0.0149 0.0785
Mycobacterium tuberculosis Probable esterase LipL 0.0086 0.0077 0.0265
Brugia malayi MH2 domain containing protein 0.0022 0.0005 0.0027
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0027 0.0012 0.0134
Leishmania major short chain dehydrogenase, putative 0.0036 0.0021 0.0107
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0038 0.0023 0.0023
Toxoplasma gondii hypothetical protein 0.0049 0.0035 0.0175
Trypanosoma cruzi dihydrolipoamide acetyltransferase, putative 0.0063 0.0051 0.042
Loa Loa (eye worm) glutamate receptor 0.0035 0.002 0.0103
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0036 0.0021 0.0021
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0028 0.0012 0.0088
Brugia malayi Inositol-1 0.0029 0.0014 0.0071
Schistosoma mansoni inositol monophosphatase 0.0029 0.0014 0.0057
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0036 0.0021 0.007
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0089 0.0079 0.0332
Schistosoma mansoni steroid dehydrogenase 0.0036 0.0021 0.0088
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0356 0.0375 0.1982
Toxoplasma gondii patched family protein 0.005 0.0037 0.0184
Loa Loa (eye worm) hypothetical protein 0.0038 0.0023 0.012
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0029 0.0014 0.01
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0081 0.0071 0.0245
Leishmania major hypothetical protein, conserved 0.0036 0.0021 0.0107
Brugia malayi Pax transcription activation domain interacting protein 0.0056 0.0044 0.023
Trypanosoma brucei short-chain dehydrogenase, putative 0.0036 0.0021 0.0102
Echinococcus multilocularis histone acetyltransferase MYST2 0.0077 0.0067 0.0066
Mycobacterium ulcerans replicative DNA helicase DnaB 0.0296 0.0309 0.4191
Brugia malayi oxidoreductase 0.0036 0.0021 0.0111
Loa Loa (eye worm) hypothetical protein 0.0086 0.0077 0.0403
Toxoplasma gondii MAPEG family protein 0.0049 0.0035 0.0175
Loa Loa (eye worm) hypothetical protein 0.008 0.007 0.0365
Onchocerca volvulus 0.0206 0.0209 0.2626
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0027 0.0012 0.0061
Trypanosoma brucei DNA damage repair protein, putative 0.0019 0.0002 0.0006
Schistosoma mansoni aldehyde dehydrogenase 0.0229 0.0234 0.0988
Trypanosoma cruzi hypothetical protein, conserved 0.0056 0.0044 0.036
Trypanosoma cruzi 3-methylcrotonyl-CoA carboxylase, putative 0.0682 0.0735 0.6093
Echinococcus granulosus cpg binding protein 0.018 0.0181 0.076
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0044 0.003 0.0146
Loa Loa (eye worm) hypothetical protein 0.005 0.0037 0.0194
Echinococcus granulosus SAM and MBT domain containing protein 0.0068 0.0056 0.0235
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0027 0.0012 0.0095
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0056 0.0044 0.0217
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0038 0.0024 0.0289
Trypanosoma cruzi acetyl-CoA carboxylase 0.1108 0.1205 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0021 0.0111
Loa Loa (eye worm) hypothetical protein 0.0036 0.0021 0.0109
Mycobacterium ulcerans short-chain dehydrogenase 0.0036 0.0021 0.0273
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0526 0.0563 0.2372
Echinococcus multilocularis lamin 0.0022 0.0006 0.0005
Onchocerca volvulus 0.0117 0.0111 0.1386
Schistosoma mansoni hypothetical protein 0.0416 0.0441 0.186
Echinococcus granulosus inositol monophosphatase 1 0.0029 0.0014 0.0056
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0036 0.0022 0.0105
Onchocerca volvulus 0.0275 0.0285 0.3594
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0043 0.0029 0.0028
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0012 0.0095
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0076 0.0065 0.0814
Schistosoma mansoni short chain dehydrogenase 0.0036 0.0021 0.0088
Leishmania major protein kinase A catalytic subunit isoform 1 0.0036 0.0022 0.011
Onchocerca volvulus 0.0036 0.0021 0.0248
Schistosoma mansoni tar DNA-binding protein 0.0272 0.0282 0.1188
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0275 0.0285 0.3873
Mycobacterium ulcerans oxidoreductase 0.0036 0.0021 0.0273
Leishmania major short chain dehydrogenase, putative 0.0036 0.0021 0.0107
Entamoeba histolytica pyruvate kinase, putative 0.0057 0.0044 0.0437
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0027 0.0012 0.0048
Loa Loa (eye worm) hypothetical protein 0.0027 0.0012 0.0059
Trichomonas vaginalis phosphofructokinase, putative 0.0041 0.0027 0.0324
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0081 0.0071 0.0245
Leishmania major acetyl-CoA carboxylase, putative 0.179 0.1958 1
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0036 0.0021 0.0273
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0036 0.0021 0.007
Mycobacterium ulcerans aldehyde dehydrogenase 0.0229 0.0234 0.3179
Trypanosoma cruzi cysteine peptidase, putative 0.0044 0.003 0.0245
Loa Loa (eye worm) hypothetical protein 0.0056 0.0044 0.0229
Mycobacterium tuberculosis Possible oxidoreductase 0.0036 0.0021 0.007
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0081 0.0071 0.0245
Loa Loa (eye worm) hypothetical protein 0.0086 0.0077 0.0403
Brugia malayi CHE-14 protein 0.0356 0.0375 0.1983
Onchocerca volvulus 0.005 0.0037 0.0451
Mycobacterium ulcerans short chain dehydrogenase 0.0036 0.0021 0.0273
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0036 0.0021 0.0254
Loa Loa (eye worm) hypothetical protein 0.0036 0.0021 0.0109
Trichomonas vaginalis antibiotic synthetase, putative 0.0081 0.0071 0.0882
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0036 0.0021 0.0021
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0027 0.0012 0.0048
Leishmania major protein kinase A catalytic subunit 0.0036 0.0022 0.011
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0029 0.0014 0.0112
Echinococcus multilocularis protein patched 0.0356 0.0375 0.0374
Loa Loa (eye worm) hypothetical protein 0.0056 0.0044 0.0229
Brugia malayi Nuclear hormone receptor family member nhr-25 0.008 0.007 0.0367
Brugia malayi PHD-finger family protein 0.0019 0.0003 0.0013
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0063 0.0051 0.0213
Toxoplasma gondii dihydrolipoyllysine-residue succinyltransferase component of oxoglutarate dehydrogenase 0.0063 0.0051 0.0254
Loa Loa (eye worm) hypothetical protein 0.0036 0.0021 0.0109
Echinococcus granulosus importin subunit beta 1 0.004 0.0026 0.0106
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0077 0.0067 0.0278
Brugia malayi RNA recognition motif domain containing protein 0.0272 0.0282 0.149
Onchocerca volvulus 0.013 0.0125 0.1569
Loa Loa (eye worm) hypothetical protein 0.008 0.007 0.0365
Loa Loa (eye worm) hypothetical protein 0.008 0.007 0.0365
Plasmodium falciparum phosphodiesterase delta, putative 0.0027 0.0012 0.0083
Schistosoma mansoni DNA ligase IV 0.0056 0.0044 0.0183
Chlamydia trachomatis replicative DNA helicase 0.0296 0.0309 0.4412
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0038 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0056 0.0044 0.0229
Plasmodium vivax DNA repair protein REV1, putative 0.0019 0.0002 0.0017
Wolbachia endosymbiont of Brugia malayi Acetyl/propionyl-CoA carboxylase, alpha subunit 0.0682 0.0735 1
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0036 0.0021 0.0102
Loa Loa (eye worm) hypothetical protein 0.005 0.0037 0.0194
Schistosoma mansoni hypothetical protein 0.0301 0.0314 0.1323
Brugia malayi RNA, U transporter 1 0.0114 0.0107 0.0566
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0036 0.0021 0.0273
Brugia malayi Patched family protein 0.005 0.0037 0.0195
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0042 0.0028 0.0117
Echinococcus multilocularis steroid dehydrogenase 0.0036 0.0021 0.0021
Loa Loa (eye worm) 6-phosphofructokinase 0.0151 0.0149 0.0784
Brugia malayi nuclear receptor NHR-67 0.0038 0.0023 0.0121
Echinococcus granulosus dihydrolipoyllysine residue acetyltransferase 0.0063 0.0051 0.0212
Schistosoma mansoni hypothetical protein 0.0343 0.0361 0.1521
Entamoeba histolytica PH domain containing protein kinase, putative 0.0036 0.0022 0.0186
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0076 0.0065 0.0541
Loa Loa (eye worm) isocitrate dehydrogenase 0.0034 0.002 0.01
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0021 0.0174
Brugia malayi AMP-binding enzyme family protein 0.0275 0.0285 0.1508
Schistosoma mansoni myst-related protein 0.0021 0.0005 0.002
Mycobacterium ulcerans short chain dehydrogenase 0.0036 0.0021 0.0273
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0036 0.0022 0.0021
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0086 0.0077 0.0265
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0193 0.0195 0.099
Mycobacterium ulcerans hypothetical protein 0.0102 0.0094 0.1267
Onchocerca volvulus 0.0131 0.0126 0.1579
Brugia malayi hypothetical protein 0.005 0.0037 0.0195
Brugia malayi mbt repeat family protein 0.0068 0.0056 0.0296
Toxoplasma gondii patched family protein 0.005 0.0037 0.0184
Trypanosoma brucei short-chain dehydrogenase, putative 0.0036 0.0021 0.0102
Mycobacterium ulcerans bifunctional protein acetyl-/propionyl-coenzyme a carboxylase (alpha chain) AccA3 0.0682 0.0735 1
Trypanosoma cruzi cysteine peptidase, putative 0.0044 0.003 0.0245
Loa Loa (eye worm) hypothetical protein 0.0038 0.0023 0.012
Trypanosoma cruzi short chain dehydrogenase, putative 0.0036 0.0021 0.0174
Echinococcus multilocularis neuropeptide receptor A26 0.0291 0.0303 0.0303
Loa Loa (eye worm) hypothetical protein 0.005 0.0037 0.0194
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0036 0.0021 0.007
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.0036 0.0021 0.0595
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0036 0.0021 0.0273
Mycobacterium ulcerans acyl-CoA synthetase 0.0081 0.0071 0.0949
Schistosoma mansoni short chain dehydrogenase 0.0036 0.0021 0.0088
Schistosoma mansoni tar DNA-binding protein 0.0272 0.0282 0.1188
Mycobacterium ulcerans propionyl-CoA carboxylase beta chain 5 AccD5 0.0243 0.025 0.3386
Chlamydia trachomatis acetyl-CoA carboxylase biotin carboxyl carrier protein 0.0063 0.0051 0.0378
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0036 0.0021 0.0174
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0028 0.0012 0.0101
Plasmodium falciparum glutathione reductase 0.0027 0.0012 0.0083
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E2 0.0063 0.0051 0.0254
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0048 0.0241
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0036 0.0021 0.0254
Schistosoma mansoni short chain dehydrogenase 0.0036 0.0021 0.0088
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0151 0.0149 0.1561
Mycobacterium ulcerans hypothetical protein 0.0019 0.0002 0.0017
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0036 0.0022 0.0179
Schistosoma mansoni retinoid-x-receptor (RXR) 0.008 0.007 0.0292
Leishmania major carbamoyl-phosphate synthase, putative 0.0154 0.0152 0.0774
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0027 0.0012 0.0083
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.008 0.007 0.0365
Loa Loa (eye worm) hypothetical protein 0.0038 0.0023 0.012
Echinococcus granulosus propionyl coenzyme A carboxylase alpha chain 0.0682 0.0735 0.3098
Schistosoma mansoni retinoic acid receptor RXR 0.008 0.007 0.0292
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0036 0.0021 0.0273
Onchocerca volvulus 0.0103 0.0096 0.1193
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0038 0.0024 0.0289
Plasmodium vivax 6-phosphofructokinase, putative 0.0041 0.0027 0.019
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.002 0.0093
Brugia malayi MH2 domain containing protein 0.0316 0.033 0.1748
Mycobacterium leprae ACETYL/PROPIONYL-CoA CARBOXYLASE (BETA SUBUNIT) ACCD6 0.0243 0.025 0.263
Onchocerca volvulus 0.005 0.0037 0.0451
Brugia malayi dehydrogenases, short chain protein 9 0.0036 0.0021 0.0111
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0027 0.0012 0.0054
Mycobacterium leprae Probable propionyl-CoA carboxylase beta chain 5 AccD5 (PCCASE) (PROPANOYL-COA:CARBON DIOXIDE LIGASE) 0.0243 0.025 0.263
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0076 0.0065 0.0814
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0027 0.0012 0.0011
Loa Loa (eye worm) DR-78 0.0038 0.0023 0.012
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0843 0.0912 0.3849
Loa Loa (eye worm) histone methyltransferase 0.0056 0.0043 0.0226
Echinococcus granulosus histone acetyltransferase MYST2 0.0077 0.0067 0.0278
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0027 0.0012 0.0083
Schistosoma mansoni cpg binding protein 0.0169 0.0169 0.071
Loa Loa (eye worm) hypothetical protein 0.0036 0.0021 0.0109
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0081 0.0071 0.0737
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0272 0.0282 0.1489
Schistosoma mansoni hypothetical protein 0.0182 0.0183 0.0769
Echinococcus multilocularis carbonyl reductase 1 0.0036 0.0021 0.0021
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0027 0.0012 0.0048
Echinococcus multilocularis expressed protein 0.0024 0.0008 0.0008
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0096 0.0087 0.044
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.008 0.007 0.0861
Echinococcus multilocularis retinol dehydrogenase 11 0.0036 0.0021 0.0021
Mycobacterium tuberculosis Conserved protein 0.0086 0.0077 0.0265
Leishmania major hypothetical protein, conserved 0.0027 0.0012 0.0059
Mycobacterium ulcerans DNA polymerase IV 0.0061 0.0048 0.0645
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.008 0.007 0.0291
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0027 0.0012 0.0037
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0021 0.0102
Brugia malayi hypothetical protein 0.0118 0.0112 0.0592
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0056 0.0044 0.0451
Loa Loa (eye worm) MH1 domain-containing protein 0.0022 0.0005 0.0026
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0076 0.0065 0.0814
Trypanosoma brucei pyruvate kinase 1 0.0081 0.0071 0.0358
Schistosoma mansoni ap endonuclease 0.0028 0.0012 0.0051
Schistosoma mansoni chromosome transmission fidelity factor 0.0056 0.0044 0.0183
Brugia malayi Nuclear hormone receptor family member nhr-3 0.008 0.007 0.0367
Wolbachia endosymbiont of Brugia malayi recombinase A 0.0083 0.0073 0.0837
Mycobacterium ulcerans acetyl-/propionyl-coenzyme a carboxylase alpha chain, AccA2 0.0682 0.0735 1
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0036 0.0021 0.0088
Loa Loa (eye worm) thioredoxin reductase 0.0027 0.0012 0.0059
Trypanosoma cruzi cysteine peptidase, putative 0.0044 0.003 0.0245
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0029 0.0014 0.0013
Onchocerca volvulus 0.0086 0.0077 0.0951
Schistosoma mansoni serine/threonine protein kinase 0.0036 0.0022 0.0091
Trypanosoma cruzi 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase, putative 0.0063 0.0051 0.042
Brugia malayi Patched family protein 0.005 0.0037 0.0195
Loa Loa (eye worm) hypothetical protein 0.005 0.0037 0.0194
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0024 0.0289
Loa Loa (eye worm) CXXC zinc finger family protein 0.0169 0.0169 0.089
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0068 0.0056 0.0236
Loa Loa (eye worm) hypothetical protein 0.0045 0.0031 0.0163
Schistosoma mansoni hypothetical protein 0.0019 0.0003 0.0011
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0096 0.0087 0.0367
Loa Loa (eye worm) hypothetical protein 0.0042 0.0028 0.0146
Loa Loa (eye worm) hypothetical protein 0.0042 0.0028 0.0146
Echinococcus multilocularis sterol regulatory element binding protein 0.0356 0.0375 0.0374
Echinococcus granulosus Nuclear hormone receptor HR96 0.0038 0.0023 0.0095
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0194 0.0196 0.0685
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0184 0.0185 0.0184
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0036 0.0021 0.0102
Trypanosoma cruzi DNA polymerase kappa, putative 0.0061 0.0048 0.04
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0036 0.0021 0.0254
Schistosoma mansoni inositol monophosphatase 0.0029 0.0014 0.0057
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0027 0.0012 0.0054
Entamoeba histolytica acyl-coA synthetase, putative 0.0275 0.0285 0.3137
Trypanosoma cruzi FHA domain containing protein, putative 0.0056 0.0044 0.036
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0117 0.0111 0.0467
Mycobacterium ulcerans hypothetical protein 0.0275 0.0285 0.3873
Trichomonas vaginalis glucosylceramidase, putative 0.0107 0.01 0.1246
Echinococcus granulosus sterol regulatory element binding protein 0.0356 0.0375 0.158
Trichomonas vaginalis hypothetical protein 0.0021 0.0004 0.0041
Brugia malayi MH2 domain containing protein 0.0022 0.0005 0.0027
Echinococcus granulosus hypothetical protein 0.0036 0.0021 0.0087
Mycobacterium ulcerans DNA polymerase IV 0.0061 0.0048 0.0645
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0081 0.0071 0.0949
Trichomonas vaginalis glucosylceramidase, putative 0.0163 0.0161 0.2028
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0182 0.0183 0.0182
Mycobacterium ulcerans acyl-CoA synthetase 0.0275 0.0285 0.3873
Mycobacterium ulcerans aldehyde dehydrogenase 0.0229 0.0234 0.3179
Trypanosoma brucei hypothetical protein, conserved 0.0086 0.0077 0.0385
Mycobacterium ulcerans acyl-CoA synthetase 0.0081 0.0071 0.0949
Schistosoma mansoni Smad4 0.0022 0.0005 0.0022
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0027 0.0012 0.0054
Echinococcus granulosus Niemann Pick C1 protein 0.1186 0.1291 0.5448
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0029 0.0014 0.0172
Loa Loa (eye worm) hypothetical protein 0.0118 0.0112 0.0591
Echinococcus multilocularis SAM and MBT domain containing protein 0.0068 0.0056 0.0056
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0038 0.0023 0.012
Echinococcus granulosus expressed conserved protein 0.078 0.0842 0.3554
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0011 0.0126
Schistosoma mansoni steroid dehydrogenase 0.0036 0.0021 0.0088
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0028 0.0012 0.0101
Brugia malayi Patched family protein 0.005 0.0037 0.0195
Leishmania major ATP-dependent phosphofructokinase 0.0151 0.0149 0.0757
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0027 0.0012 0.0054
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0029 0.0014 0.0097
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0081 0.0071 0.0585
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0038 0.0024 0.0289
Loa Loa (eye worm) mbt repeat family protein 0.0068 0.0056 0.0295
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0036 0.0021 0.0174
Brugia malayi Carboxyl transferase domain containing protein 0.1728 0.1889 1
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0002 0.0018
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0028 0.0135
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0036 0.0021 0.0174
Brugia malayi tailless protein 0.0038 0.0023 0.0121
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0022 0.0005 0.0005
Trypanosoma cruzi DNA damage repair protein, putative 0.0019 0.0002 0.0018
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0036 0.0021 0.015
Schistosoma mansoni steroid dehydrogenase 0.0036 0.0021 0.0088
Echinococcus multilocularis smad 0.0022 0.0005 0.0005
Brugia malayi Intermediate filament tail domain containing protein 0.0022 0.0006 0.0027
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.004 0.0026 0.0211
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0036 0.0022 0.0155
Trypanosoma cruzi DNA polymerase eta, putative 0.0061 0.0048 0.04
Trichomonas vaginalis ap endonuclease, putative 0.0028 0.0012 0.0143
Loa Loa (eye worm) hypothetical protein 0.0036 0.0021 0.0109
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0036 0.0022 0.0114
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0001 0.0002
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0022 0.0005 0.0022
Entamoeba histolytica acyl-CoA synthetase, putative 0.0275 0.0285 0.3137
Trypanosoma cruzi dihydrolipoamide acetyltransferase precursor, putative 0.0063 0.0051 0.042
Leishmania major dehydrogenase-like protein 0.0036 0.0021 0.0107
Schistosoma mansoni RAR-like nuclear receptor 0.008 0.007 0.0292
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0027 0.0012 0.0083
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0021 0.0111
Leishmania major quinonoid dihydropteridine reductase 0.0036 0.0021 0.0107
Brugia malayi Patched related family protein 4 0.005 0.0037 0.0195
Brugia malayi Metabotropic glutamate receptor precursor. 0.0035 0.002 0.0104
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0029 0.0014 0.016
Echinococcus multilocularis retinol dehydrogenase 11 0.0036 0.0021 0.0021
Schistosoma mansoni carbonyl reductase 0.0036 0.0021 0.0088
Loa Loa (eye worm) hypothetical protein 0.0057 0.0044 0.0231
Wolbachia endosymbiont of Brugia malayi carbamoyl phosphate synthase large subunit 0.0154 0.0152 0.193
Toxoplasma gondii hypothetical protein 0.0031 0.0016 0.0076
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0275 0.0285 0.0998
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0028 0.0012 0.0088
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.008 0.007 0.0292
Plasmodium vivax lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, putative 0.0063 0.0051 0.0361
Loa Loa (eye worm) hypothetical protein 0.0038 0.0023 0.012
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0062 0.005 0.0173
Echinococcus granulosus geminin 0.142 0.1549 0.6536
Brugia malayi Nuclear hormone receptor-like 1 0.0042 0.0028 0.0147
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0065 0.0814
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0024 0.0008 0.0061
Mycobacterium tuberculosis Probable branched-chain keto acid dehydrogenase E2 component BkdC 0.0063 0.0051 0.0175
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0027 0.0012 0.0054
Mycobacterium ulcerans short chain dehydrogenase 0.0036 0.0021 0.0273
Plasmodium vivax hypothetical protein, conserved 0.0086 0.0077 0.0543
Mycobacterium ulcerans ketoacyl reductase 0.0036 0.0021 0.0273
Echinococcus multilocularis dna polymerase eta 0.0061 0.0048 0.0048
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0027 0.0012 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0024 0.0289
Schistosoma mansoni hypothetical protein 0.142 0.1549 0.6536
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0027 0.0011 0.0126
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0029 0.0014 0.0115
Trypanosoma cruzi pyruvate kinase 2, putative 0.0081 0.0071 0.0589
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0052 0.0039 0.0162
Chlamydia trachomatis pyruvate kinase 0.0081 0.0071 0.0697
Leishmania major DNA polymerase kappa, putative 0.0019 0.0002 0.0011
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0036 0.0021 0.0021
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0036 0.0021 0.007
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0045 0.0031 0.0381
Loa Loa (eye worm) phosphofructokinase 0.0151 0.0149 0.0784
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0081 0.0071 0.0949
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.002 0.0019
Trypanosoma cruzi pyruvate kinase 2, putative 0.0081 0.0071 0.0589
Mycobacterium leprae Probable biotinylated protein homolog TB7.3 0.0063 0.0051 0.0527
Trypanosoma cruzi DNA damage repair protein, putative 0.0019 0.0002 0.0018
Brugia malayi Patched family protein 0.005 0.0037 0.0195
Echinococcus granulosus tumor protein p63 0.0654 0.0704 0.2968
Leishmania major acetyl-CoA synthetase, putative 0.0081 0.0071 0.036
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0056 0.0044 0.0539
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0036 0.0021 0.002
Mycobacterium tuberculosis Probable reductase 0.0062 0.005 0.0173
Loa Loa (eye worm) oxidoreductase 0.0036 0.0021 0.0109
Entamoeba histolytica phosphofructokinase, putative 0.0151 0.0149 0.1606
Echinococcus multilocularis pyruvate kinase 0.0081 0.0071 0.0071
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0036 0.0021 0.0111
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0163 0.0161 0.0851
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0027 0.0011 0.005
Schistosoma mansoni sex comb on midleg homolog 0.0068 0.0056 0.0236
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0021 0.0111
Loa Loa (eye worm) hypothetical protein 0.008 0.007 0.0365
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0283 0.0294 0.1239
Onchocerca volvulus 0.005 0.0037 0.0451
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0061 0.0048 0.0246
Loa Loa (eye worm) hypothetical protein 0.1009 0.1096 0.5799
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0021 0.0111
Loa Loa (eye worm) hypothetical protein 0.0042 0.0028 0.0146
Trichomonas vaginalis glucosylceramidase, putative 0.0107 0.01 0.1246
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0184 0.0185 0.0938
Giardia lamblia Acetyl-CoA carboxylase/pyruvate carboxylase fusion protein, putative 0.0305 0.0319 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0027 0.0012 0.0054
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0021 0.0174
Echinococcus granulosus neuropeptide s receptor 0.0291 0.0303 0.1278
Brugia malayi Niemann-Pick C1 protein precursor 0.083 0.0898 0.4753
Onchocerca volvulus 0.0036 0.0021 0.0248
Mycobacterium ulcerans short chain dehydrogenase 0.0036 0.0021 0.0273
Trichomonas vaginalis glucosylceramidase, putative 0.0163 0.0161 0.2028
Mycobacterium ulcerans dehydrogenase/reductase 0.0036 0.0021 0.0273
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0081 0.0071 0.0355
Brugia malayi AMP-binding enzyme family protein 0.0081 0.0071 0.0373
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0283 0.0294 0.0293
Schistosoma mansoni hypothetical protein 0.0095 0.0087 0.0365
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0262 0.0271 0.1142
Chlamydia trachomatis biotin carboxylase 0.0619 0.0665 1
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0021 0.0102
Loa Loa (eye worm) hypothetical protein 0.005 0.0037 0.0194
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0029 0.0014 0.0065
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0036 0.0021 0.007
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0036 0.0021 0.0273
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0086 0.0077 0.0322
Loa Loa (eye worm) hypothetical protein 0.0039 0.0025 0.013
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0024 0.0008 0.0038
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.008 0.007 0.0069
Echinococcus granulosus carbonyl reductase 1 0.0036 0.0021 0.0087
Echinococcus granulosus rho-associated protein kinase 1 0.0131 0.0126 0.053
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0024 0.0289
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0044 0.003 0.0146
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0048 0.0241
Loa Loa (eye worm) hypothetical protein 0.0205 0.0208 0.1101
Echinococcus granulosus PHD finger protein rhinoceros 0.0019 0.0003 0.0009
Mycobacterium ulcerans hypothetical protein 0.0063 0.0051 0.0678
Trichomonas vaginalis penicillin-binding protein, putative 0.0086 0.0077 0.0956
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0038 0.0023 0.0273
Echinococcus granulosus dna polymerase eta 0.0061 0.0048 0.0202
Onchocerca volvulus 0.0086 0.0077 0.0951
Loa Loa (eye worm) hypothetical protein 0.005 0.0037 0.0194
Loa Loa (eye worm) hypothetical protein 0.0205 0.0208 0.1101
Leishmania major pteridine reductase 1 0.0036 0.0021 0.0107
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.008 0.007 0.0069
Echinococcus granulosus propionyl coenzyme A carboxylase beta chain 0.0243 0.025 0.1051
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0036 0.0022 0.0021
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0004 0.0041
Trypanosoma brucei importin beta-1 subunit, putative 0.004 0.0026 0.0125
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0034 0.002 0.0093
Trypanosoma brucei DNA polymerase IV, putative 0.0061 0.0048 0.0241
Echinococcus multilocularis cpg binding protein 0.018 0.0181 0.018
Toxoplasma gondii carbonyl reductase 1, putative 0.0036 0.0021 0.0102
Trichomonas vaginalis rotamase, putative 0.0024 0.0008 0.009
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0027 0.0012 0.0054
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0021 0.0102
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0081 0.0071 0.0245
Brugia malayi hypothetical protein 0.0038 0.0023 0.0121
Brugia malayi Thioredoxin reductase 0.0027 0.0012 0.0061
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0036 0.0021 0.0273
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0076 0.0065 0.0328
Brugia malayi AMP-binding enzyme family protein 0.0081 0.0071 0.0373
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0035 0.0433
Echinococcus granulosus mothers against decapentaplegic 5 0.0022 0.0005 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0044 0.0539
Loa Loa (eye worm) hypothetical protein 0.0182 0.0183 0.0964
Schistosoma mansoni acetyl-CoA synthetase 0.0081 0.0071 0.0297
Schistosoma mansoni tar DNA-binding protein 0.0272 0.0282 0.1188
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0262 0.0271 0.1434
Toxoplasma gondii propionate-CoA ligase 0.0081 0.0071 0.0356
Chlamydia trachomatis dihydrolipoamide acetyltransferase 0.0063 0.0051 0.0378
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0021 0.0111
Schistosoma mansoni short chain dehydrogenase 0.0036 0.0021 0.0088
Echinococcus multilocularis dihydrolipoyllysine residue succinyltransferase 0.0063 0.0051 0.005
Loa Loa (eye worm) hypothetical protein 0.005 0.0037 0.0194
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0076 0.0065 0.0065
Entamoeba histolytica hypothetical protein, conserved 0.0036 0.0021 0.018
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0036 0.0021 0.0273
Toxoplasma gondii PHD-finger domain-containing protein 0.0019 0.0003 0.0009
Schistosoma mansoni hypothetical protein 0.0343 0.0361 0.1521
Echinococcus granulosus phosphatidylinositol 5 phosphate 4 kinase type 2 0.0117 0.0111 0.0466
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0034 0.002 0.016
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0027 0.0012 0.0059
Trichomonas vaginalis pyruvate kinase, putative 0.0081 0.0071 0.0888
Trypanosoma cruzi DNA polymerase kappa, putative 0.0061 0.0048 0.04
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0182 0.0183 0.0768
Trypanosoma brucei hypothetical protein, conserved 0.0019 0.0002 0.0006
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0095 0.0087 0.0086
Loa Loa (eye worm) oxidoreductase 0.0036 0.0021 0.0109
Leishmania major hypothetical protein, conserved 0.0036 0.0021 0.0107
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.083 0.0898 1
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0036 0.0021 0.0174
Brugia malayi glutathione reductase 0.0027 0.0012 0.0061
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0027 0.0012 0.0054
Loa Loa (eye worm) hypothetical protein 0.0028 0.0013 0.0065
Trypanosoma cruzi DNA repair protein, putative 0.0025 0.001 0.0079
Entamoeba histolytica Ran family GTPase 0.0029 0.0014 0.01
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0076 0.0065 0.0274
Echinococcus multilocularis steroid dehydrogenase 0.0036 0.0021 0.0021
Onchocerca volvulus 0.008 0.007 0.0861
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0036 0.0021 0.0254
Mycobacterium ulcerans acetyl-CoA synthetase 0.0081 0.0071 0.0949
Trichomonas vaginalis inositol monophosphatase, putative 0.0029 0.0014 0.016
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0036 0.0021 0.0102
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0076 0.0065 0.0814
Schistosoma mansoni short chain dehydrogenase 0.0036 0.0021 0.0088
Brugia malayi Importin beta-1 subunit 0.004 0.0026 0.0135
Toxoplasma gondii PHD-finger domain-containing protein 0.0019 0.0003 0.0009
Echinococcus multilocularis survival motor neuron protein 1 0.1009 0.1096 0.1095
Mycobacterium leprae Probable lipase LipE 0.0086 0.0077 0.0799
Leishmania major protein kinase A catalytic subunit isoform 2 0.0036 0.0022 0.011
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0045 0.0031 0.0164
Brugia malayi Pyruvate kinase, M2 isozyme 0.0081 0.0071 0.0376
Brugia malayi Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial precursor, puta 0.0063 0.0051 0.0268
Toxoplasma gondii carbamoylphosphate synthetase 0.0154 0.0152 0.077
Treponema pallidum pyruvate carboxylase subunit B 0.0063 0.0051 0.1298
Mycobacterium tuberculosis DlaT, dihydrolipoamide acyltransferase, E2 component of pyruvate dehydrogenase 0.0063 0.0051 0.0175
Brugia malayi Pre-SET motif family protein 0.0096 0.0087 0.046
Schistosoma mansoni pyruvate carboxylase 0.0682 0.0735 0.3099
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0027 0.0012 0.0134
Plasmodium vivax dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, putative 0.0063 0.0051 0.0361
Brugia malayi Patched related family protein 10 0.005 0.0037 0.0195
Loa Loa (eye worm) hypothetical protein 0.005 0.0037 0.0194
Schistosoma mansoni smad1 5 8 and 0.0022 0.0005 0.0022
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.008 0.007 0.0365
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0029 0.0014 0.0066
Onchocerca volvulus Pyruvate kinase homolog 0.0081 0.0071 0.0883
Mycobacterium ulcerans short chain dehydrogenase 0.0036 0.0021 0.0273
Leishmania major dihydrolipoamide branched chain transacylase, putative 0.0063 0.0051 0.0259
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0029 0.0014 0.0019
Onchocerca volvulus Glucosylceramidase homolog 0.0107 0.01 0.1241
Loa Loa (eye worm) oxidoreductase 0.0036 0.0021 0.0109
Mycobacterium tuberculosis Probable lipase LipD 0.0086 0.0077 0.0265
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0028 0.0012 0.0057
Loa Loa (eye worm) hypothetical protein 0.0038 0.0023 0.012
Plasmodium falciparum DNA repair protein REV1, putative 0.0019 0.0002 0.0017
Echinococcus multilocularis propionyl coenzyme A carboxylase alpha chain 0.0682 0.0735 0.0734
Toxoplasma gondii acetyl-coA carboxylase ACC2 0.179 0.1958 1
Brugia malayi jmjC domain containing protein 0.0063 0.0051 0.0269
Loa Loa (eye worm) hypothetical protein 0.0038 0.0023 0.012
Onchocerca volvulus 0.0036 0.0021 0.0248
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0182 0.0183 0.0965
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0028 0.0012 0.005
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0038 0.0023 0.0023
Mycobacterium tuberculosis Probable dehydrogenase 0.0062 0.005 0.0173
Schistosoma mansoni smad 0.0022 0.0005 0.0022
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0036 0.0022 0.0021
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0029 0.0014 0.0372
Echinococcus multilocularis phosphatidylinositol 5 phosphate 4 kinase type 2 0.0117 0.0111 0.011
Brugia malayi polk-prov protein 0.0019 0.0002 0.0011
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0041 0.0027 0.019
Schistosoma mansoni pyruvate kinase 0.0081 0.0071 0.0299
Trypanosoma brucei pyruvate kinase 1, putative 0.0081 0.0071 0.0358
Brugia malayi photoreceptor-specific nuclear receptor 0.008 0.007 0.0367
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0086 0.0077 0.0404
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0002 0.0006
Giardia lamblia Pyruvate kinase 0.0081 0.0071 0.2177
Echinococcus multilocularis geminin 0.142 0.1549 0.1548
Loa Loa (eye worm) TAR-binding protein 0.0272 0.0282 0.1489
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0027 0.0012 0.0134
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.008 0.007 0.0365
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0029 0.0014 0.0014
Schistosoma mansoni DNA polymerase IV / kappa 0.0019 0.0002 0.0009
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0081 0.0071 0.0949
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.0093
Loa Loa (eye worm) hypothetical protein 0.0027 0.0012 0.0059
Loa Loa (eye worm) hypothetical protein 0.0275 0.0285 0.1507
Brugia malayi hypothetical protein 0.005 0.0037 0.0195
Schistosoma mansoni carbonyl reductase 0.0036 0.0021 0.0088
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0076 0.0065 0.0275
Trypanosoma brucei pyruvate dehydrogenase complex E3 binding protein, putative 0.0063 0.0051 0.0253
Schistosoma mansoni sex comb on midleg homolog 0.0068 0.0056 0.0236
Brugia malayi DKFZp564C0469 protein 0.0056 0.0044 0.023
Loa Loa (eye worm) oxidoreductase 0.0036 0.0021 0.0109
Trichomonas vaginalis helicase, putative 0.0038 0.0024 0.0289
Loa Loa (eye worm) hypothetical protein 0.0061 0.0048 0.0254
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0024 0.0289
Schistosoma mansoni pyruvate kinase 0.0081 0.0071 0.0299
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0021 0.0174
Echinococcus multilocularis expressed conserved protein 0.078 0.0842 0.0842
Loa Loa (eye worm) hypothetical protein 0.0205 0.0208 0.1101
Leishmania major hypothetical protein, conserved 0.0036 0.0021 0.0107
Brugia malayi jmjC domain containing protein 0.0034 0.0019 0.0101
Mycobacterium ulcerans pyruvate kinase 0.0081 0.0071 0.0956
Echinococcus granulosus Nuclear hormone receptor HR96 0.0038 0.0023 0.0095
Brugia malayi Patched related family protein 12 0.005 0.0037 0.0195
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0301 0.0314 0.0313
Schistosoma mansoni short chain dehydrogenase 0.0036 0.0021 0.0088
Schistosoma mansoni Tr4/Tr2 (homologue) 0.008 0.007 0.0292
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0061 0.0048 0.0202
Loa Loa (eye worm) hypothetical protein 0.0117 0.0111 0.0585
Leishmania major cathepsin L-like protease 0.0044 0.003 0.0151
Schistosoma mansoni 6-phosphofructokinase 0.0151 0.0149 0.0626
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0027 0.0012 0.0054
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0045 0.0031 0.0164
Mycobacterium leprae Probable pyruvate kinase PykA 0.0081 0.0071 0.0743
Schistosoma mansoni nuclear receptor 0.0038 0.0023 0.0096
Mycobacterium tuberculosis Possible penicillin-binding protein 0.055 0.0588 0.2063
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0022 0.0006 0.0026
Trichomonas vaginalis glucosylceramidase, putative 0.0113 0.0106 0.1326
Brugia malayi MH1 domain containing protein 0.0022 0.0005 0.0027
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0045 0.0031 0.0381
Brugia malayi Nuclear hormone receptor family member nhr-1 0.008 0.007 0.0367
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0012 0.0095
Echinococcus multilocularis polycomb protein SCMH1 0.0068 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0056 0.0044 0.0229
Loa Loa (eye worm) hypothetical protein 0.008 0.007 0.0365
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0229 0.0234 0.0986
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0048 0.0241
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0063 0.0051 0.005
Schistosoma mansoni microsomal glutathione s-transferase 0.0049 0.0035 0.0148
Schistosoma mansoni zinc finger protein 0.0023 0.0007 0.003
Trypanosoma brucei unspecified product 0.0042 0.0028 0.0135
Loa Loa (eye worm) hypothetical protein 0.0275 0.0285 0.1507
Giardia lamblia hypothetical protein 0.0027 0.0012 0.0296
Leishmania major pyruvate kinase 0.0081 0.0071 0.0363
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0036 0.0021 0.0088
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0229 0.0234 0.1195
Schistosoma mansoni hypothetical protein 0.142 0.1549 0.6536
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0036 0.0021 0.0273
Brugia malayi Patched family protein 0.005 0.0037 0.0195
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0081 0.0071 0.0245
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0029 0.0014 0.0115
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0021 0.0111
Onchocerca volvulus 0.0086 0.0077 0.0951
Schistosoma mansoni nuclear hormone receptor 0.0038 0.0023 0.0096
Loa Loa (eye worm) patched family protein 0.005 0.0037 0.0194
Toxoplasma gondii histone lysine methyltransferase SET1 0.0326 0.0341 0.1738
Loa Loa (eye worm) hypothetical protein 0.0068 0.0056 0.0295
Giardia lamblia Replication factor C, subunit 1 0.0056 0.0044 0.1306
Mycobacterium ulcerans acyl-CoA synthetase 0.0081 0.0071 0.0949
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0036 0.0021 0.0273
Brugia malayi orphan nuclear receptor NR2E1 0.0038 0.0023 0.0121
Brugia malayi RNA binding protein 0.0272 0.0282 0.149
Schistosoma mansoni myst-related protein 0.0021 0.0005 0.002
Onchocerca volvulus 0.0733 0.0791 1
Trichomonas vaginalis D-aminoacylase, putative 0.0086 0.0077 0.0956
Echinococcus multilocularis Biotin lipoyl attachment 0.0063 0.0051 0.005
Echinococcus multilocularis pyruvate kinase 0.0042 0.0028 0.0027
Loa Loa (eye worm) RNA binding protein 0.0272 0.0282 0.1489
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0036 0.0021 0.0109
Schistosoma mansoni short chain dehydrogenase 0.0036 0.0021 0.0088
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0076 0.0065 0.0814
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0061 0.0048 0.0166
Trichomonas vaginalis phosphofructokinase, putative 0.0151 0.0149 0.1867
Trichomonas vaginalis glucosylceramidase, putative 0.0107 0.01 0.1246
Mycobacterium ulcerans short chain dehydrogenase 0.0036 0.0021 0.0273
Onchocerca volvulus 0.0056 0.0044 0.0533
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0036 0.0021 0.0102
Brugia malayi exodeoxyribonuclease III family protein 0.0028 0.0012 0.0064
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0076 0.0065 0.0814
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0076 0.0065 0.0814
Loa Loa (eye worm) beta-lactamase 0.0086 0.0077 0.0403
Schistosoma mansoni hypothetical protein 0.0182 0.0183 0.0769
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0026 0.001 0.0033
Brugia malayi Patched family protein 0.005 0.0037 0.0195
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0027 0.0012 0.0048
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0027 0.0012 0.0095
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0036 0.0021 0.007
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0056 0.0043 0.018
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0193 0.0195 0.1617
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0027 0.0011 0.0126
Brugia malayi Smad1 0.0022 0.0005 0.0027
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0036 0.0021 0.015
Echinococcus granulosus nuclear receptor nhr 48 0.0038 0.0023 0.0095
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0036 0.0021 0.0021
Toxoplasma gondii 2-oxo acid dehydrogenases acyltransferase (catalytic domain) domain-containing protein 0.0063 0.0051 0.0254
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.008 0.007 0.0292
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0027 0.0012 0.0054
Schistosoma mansoni thyroid hormone receptor 0.0175 0.0175 0.0737
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0036 0.0021 0.0248
Loa Loa (eye worm) hypothetical protein 0.005 0.0037 0.0194
Echinococcus granulosus smad 0.0022 0.0005 0.002
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0062 0.005 0.0521
Echinococcus granulosus metabotropic glutamate receptor 2 0.0029 0.0014 0.0055
Brugia malayi latrophilin 2 splice variant baaae 0.0393 0.0416 0.2199
Treponema pallidum recombinase A 0.0083 0.0073 0.2043
Trypanosoma brucei glutamine hydrolysing (not ammonia-dependent) carbomoyl phosphate synthase, putative 0.0154 0.0152 0.0769
Schistosoma mansoni hypothetical protein 0.0343 0.0361 0.1521
Echinococcus granulosus ecdysone induced protein 78C 0.008 0.007 0.0291
Onchocerca volvulus 0.0036 0.0021 0.0248
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0229 0.0234 0.0234
Loa Loa (eye worm) jmjC domain-containing protein 0.0034 0.0019 0.01
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0076 0.0065 0.0541
Loa Loa (eye worm) hypothetical protein 0.005 0.0037 0.0194
Plasmodium falciparum acyl-CoA synthetase 0.0205 0.0208 0.1476
Loa Loa (eye worm) hypothetical protein 0.005 0.0037 0.0194
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0029 0.0014 0.0073
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.008 0.007 0.0365
Schistosoma mansoni short chain dehydrogenase 0.0036 0.0021 0.0088
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0036 0.0022 0.009
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0262 0.0271 0.1143
Echinococcus granulosus expressed protein 0.0024 0.0008 0.0032
Loa Loa (eye worm) hypothetical protein 0.0036 0.0021 0.0109
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0081 0.0071 0.0245
Mycobacterium ulcerans acyl-CoA synthetase 0.0081 0.0071 0.0949
Loa Loa (eye worm) hypothetical protein 0.0436 0.0463 0.2451
Schistosoma mansoni carbamoyl-phosphate synthetase 0.0154 0.0152 0.064
Echinococcus granulosus neuropeptide receptor A26 0.0291 0.0303 0.1278
Mycobacterium tuberculosis Probable oxidoreductase 0.0036 0.0021 0.007
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0027 0.0012 0.0047
Echinococcus granulosus retinol dehydrogenase 11 0.0036 0.0021 0.0087
Trypanosoma brucei hypothetical protein, conserved 0.0019 0.0002 0.0006
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0027 0.0012 0.0083
Giardia lamblia DINP protein human, muc B family 0.0061 0.0048 0.1456
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0012 0.0134
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0027 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.0086 0.0077 0.0403
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0027 0.0011 0.0045
Onchocerca volvulus Alhambra homolog 0.0019 0.0003 0.0016
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.002 0.0019
Brugia malayi Nuclear hormone receptor family member nhr-40 0.008 0.007 0.0367
Schistosoma mansoni acetyl-CoA carboxylase 0.179 0.1958 0.8265
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0056 0.0044 0.0539
Echinococcus granulosus FTZ F1 alpha 0.008 0.007 0.0291
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0029 0.0014 0.0064
Loa Loa (eye worm) pyruvate kinase-PB 0.0057 0.0044 0.0231
Schistosoma mansoni terminal deoxycytidyl transferase 0.0061 0.0048 0.0203
Echinococcus multilocularis isocitrate dehydrogenase 0.0034 0.002 0.0019
Loa Loa (eye worm) hypothetical protein 0.005 0.0037 0.0194
Schistosoma mansoni lamin 0.0022 0.0006 0.0022
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0038 0.0024 0.0289
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0151 0.0149 0.0753
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0027 0.0012 0.0134
Onchocerca volvulus 0.0068 0.0056 0.0692
Trypanosoma cruzi glutamine-dependent carbamoyl-phosphate synthetase, putative 0.0154 0.0152 0.1258
Mycobacterium leprae Probable propyonyl-CoA carboxylase beta chain 4 AccD4 (Pccase) 0.0243 0.025 0.263
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0036 0.0021 0.0254
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0019 0.0003 0.0011
Schistosoma mansoni serine/threonine protein kinase 0.0036 0.0022 0.0091
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0076 0.0065 0.0814
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0012 0.0095
Brugia malayi Bromodomain containing protein 0.0021 0.0005 0.0023
Echinococcus multilocularis propionyl coenzyme A carboxylase beta chain 0.0243 0.025 0.0249
Schistosoma mansoni steroid dehydrogenase 0.0036 0.0021 0.0088
Trichomonas vaginalis esterase, putative 0.0086 0.0077 0.0956
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0025 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0038 0.0023 0.012
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0205 0.0208 0.2827
Trichomonas vaginalis phosphofructokinase, putative 0.0151 0.0149 0.1867
Giardia lamblia Short-chain dehydrogenase, putative 0.0036 0.0021 0.0595
Schistosoma mansoni nuclear hormone receptor 0.008 0.007 0.0292
Trypanosoma cruzi DNA polymerase kappa, putative 0.0061 0.0048 0.04
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0081 0.0071 0.0246
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0028 0.0135
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0027 0.0012 0.0095
Echinococcus granulosus oxidoreductase 0.0036 0.0021 0.0087
Loa Loa (eye worm) hypothetical protein 0.0063 0.0051 0.0267
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0107 0.01 0.01
Brugia malayi Isocitrate dehydrogenase 0.0034 0.002 0.0102
Loa Loa (eye worm) hypothetical protein 0.0043 0.0029 0.015
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0575 0.0617 0.3262
Schistosoma mansoni steroid dehydrogenase 0.0036 0.0021 0.0088
Schistosoma mansoni 6-phosphofructokinase 0.0151 0.0149 0.0626
Mycobacterium ulcerans lipase LipD 0.0086 0.0077 0.1029
Brugia malayi Bromodomain containing protein 0.0027 0.0011 0.0057
Onchocerca volvulus Pyruvate kinase homolog 0.0081 0.0071 0.0883
Brugia malayi hypothetical protein 0.0042 0.0028 0.0147
Mycobacterium leprae PROBABLE REPLICATIVE DNA HELICASE DNAB replicative DNA helicase 0.0296 0.0309 0.3255
Trypanosoma cruzi dihydrolipoamide branched chain transacylase, putative 0.0063 0.0051 0.042
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0025 0.0009 0.0036
Leishmania major quinonoid dihydropteridine reductase 0.0036 0.0021 0.0107
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0056 0.0044 0.023
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0019 0.0002 0.0006
Mycobacterium ulcerans propionyl-CoA carboxylase beta chain 4 AccD4_2 0.0243 0.025 0.3386
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. 0.2383 0.2612 0.9172
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0028 0.0012 0.0154
Onchocerca volvulus Bile acid receptor homolog 0.008 0.007 0.0861
Onchocerca volvulus 0.0081 0.0071 0.0877
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0036 0.0022 0.0105
Onchocerca volvulus 0.0036 0.0021 0.0248
Loa Loa (eye worm) hypothetical protein 0.0063 0.0051 0.0267
Loa Loa (eye worm) twinkle helicase 0.0085 0.0075 0.0395
Trichomonas vaginalis importin beta-1, putative 0.0032 0.0017 0.0206
Onchocerca volvulus 0.0096 0.0087 0.1085
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0045 0.0031 0.0129
Schistosoma mansoni hypothetical protein 0.0427 0.0453 0.191
Schistosoma mansoni steroid dehydrogenase 0.0036 0.0021 0.0088
Trypanosoma brucei DNA damage repair protein, putative 0.0019 0.0002 0.0006
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0038 0.0024 0.0289
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0044 0.0539
Mycobacterium ulcerans short chain dehydrogenase 0.0036 0.0021 0.0273
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.008 0.007 0.0365
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0036 0.0021 0.0174
Loa Loa (eye worm) hypothetical protein 0.005 0.0037 0.0194
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0044 0.003 0.0146
Schistosoma mansoni smad1 5 8 and 0.0022 0.0005 0.0022
Plasmodium falciparum thioredoxin reductase 0.0027 0.0012 0.0083
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0107 0.01 0.0422
Echinococcus multilocularis replication factor c subunit 1 0.0056 0.0044 0.0043
Entamoeba histolytica acetyl-coA carboxylase, putative 0.0305 0.0319 0.3512
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0076 0.0065 0.0814
Wolbachia endosymbiont of Brugia malayi replicative DNA helicase 0.0296 0.0309 0.41
Brugia malayi Dehydrogenases, short chain protein 2 0.0036 0.0021 0.0111
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0076 0.0065 0.0814
Brugia malayi 6-phosphofructokinase 0.0151 0.0149 0.0785
Trichomonas vaginalis ran, putative 0.0029 0.0014 0.0164
Loa Loa (eye worm) hypothetical protein 0.0086 0.0077 0.0403
Mycobacterium tuberculosis Probable replicative DNA helicase DnaB 0.2596 0.2848 1
Mycobacterium ulcerans propionyl-CoA carboxylase beta chain 4 AccD4 0.0243 0.025 0.3386
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0184 0.0185 0.0939
Schistosoma mansoni steroid hormone receptor ad4bp 0.008 0.007 0.0292
Brugia malayi N-terminal motif family protein 0.0125 0.0119 0.063
Trypanosoma cruzi DNA polymerase kappa, putative 0.0061 0.0048 0.04
Trichomonas vaginalis phosphofructokinase, putative 0.0041 0.0027 0.0324
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0184 0.0185 0.0778
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0044 0.003 0.0146
Brugia malayi PHD-finger family protein 0.0017 0.0001 0.0002
Loa Loa (eye worm) steroid hormone receptor 0.008 0.007 0.0365
Chlamydia trachomatis dihydrolipoamide succinyltransferase 0.0063 0.0051 0.0378
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0001 0.0002
Mycobacterium ulcerans 6-phosphofructokinase 0.0151 0.0149 0.201
Echinococcus granulosus dihydrolipoyllysine residue succinyltransferase 0.0063 0.0051 0.0212
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0019 0.0002 0.0006
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0151 0.0149 0.1231
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0275 0.0285 0.3009
Brugia malayi steroid hormone receptor 0.008 0.007 0.0367
Echinococcus granulosus polycomb protein SCMH1 0.0068 0.0056 0.0235
Echinococcus granulosus Niemann Pick C1 protein 0.083 0.0898 0.3788
Toxoplasma gondii pyruvate kinase PyK1 0.0081 0.0071 0.0358
Leishmania major DNA polymerase eta, putative 0.0019 0.0002 0.0011
Toxoplasma gondii HEAT repeat-containing protein 0.004 0.0026 0.0126
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0024 0.0289
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0036 0.0021 0.0102
Brugia malayi hypothetical protein 0.1009 0.1096 0.5799
Echinococcus granulosus fetal alzheimer antigen falz 0.0025 0.001 0.0038
Echinococcus granulosus pyruvate kinase 0.0081 0.0071 0.0298
Trichomonas vaginalis antibiotic synthetase, putative 0.0081 0.0071 0.0882
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0262 0.0271 0.0271
Leishmania major 4-coumarate:coa ligase-like protein 0.0275 0.0285 0.1455
Brugia malayi mbt repeat family protein 0.0068 0.0056 0.0296
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0036 0.0021 0.0212
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0526 0.0563 0.2977
Mycobacterium leprae conserved hypothetical protein 0.0086 0.0077 0.0799
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0036 0.0021 0.018
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0042 0.0028 0.0027
Echinococcus granulosus pyruvate kinase 0.0042 0.0028 0.0114
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0081 0.0071 0.0355
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0676 0.0728 0.3853
Echinococcus multilocularis neuropeptide s receptor 0.0291 0.0303 0.0303
Brugia malayi Lipoamide acyltransferase component of branched-chain alpha-keto aciddehydrogenase complex, mitochondrial precursor 0.0063 0.0051 0.0268
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0024 0.0008 0.0061
Schistosoma mansoni ap endonuclease 0.0028 0.0012 0.0051
Brugia malayi Patched family protein 0.005 0.0037 0.0195
Trypanosoma cruzi major cysteine proteinase, putative 0.0034 0.002 0.016
Mycobacterium ulcerans hypothetical protein 0.0086 0.0077 0.1029
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0205 0.0208 0.0728
Schistosoma mansoni jumonji/arid domain-containing protein 0.0034 0.0019 0.0081
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0027 0.0012 0.0095
Onchocerca volvulus Protein ultraspiracle homolog 0.008 0.007 0.0861
Mycobacterium ulcerans short-chain dehydrogenase 0.0036 0.0021 0.0273
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0262 0.0271 0.1143
Leishmania major cAMP-specific phosphodiesterase, putative 0.0027 0.0012 0.0059
Loa Loa (eye worm) pyruvate kinase 0.0081 0.0071 0.0375
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0027 0.0012 0.0134
Brugia malayi hypothetical protein 0.0036 0.0021 0.0111
Loa Loa (eye worm) hypothetical protein 0.0081 0.0071 0.0372
Echinococcus multilocularis tar DNA binding protein 0.0272 0.0282 0.0281
Leishmania major short chain dehydrogenase-like protein 0.0036 0.0021 0.0107
Echinococcus multilocularis carbonyl reductase 1 0.0036 0.0021 0.0021
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0045 0.0032 0.0031
Plasmodium vivax steroid dehydrogenase, putative 0.0036 0.0021 0.015
Brugia malayi hypothetical protein 0.0038 0.0023 0.0121
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0262 0.0271 0.0271
Schistosoma mansoni aspartate carbamoyltransferase 0.0154 0.0152 0.064
Giardia lamblia Reductase, putative 0.0036 0.0021 0.0595
Wolbachia endosymbiont of Brugia malayi Acetyl-CoA carboxylase, carboxyltransferase component 0.0243 0.025 0.3283
Mycobacterium ulcerans dihydrolipoamide acetyltransferase 0.0063 0.0051 0.0678
Loa Loa (eye worm) carboxyl transferase domain-containing protein 0.1728 0.1889 1
Schistosoma mansoni methylcrotonyl-CoA carboxylase 0.0682 0.0735 0.3099
Toxoplasma gondii acyl-CoA carboxyltransferase beta chain, putative 0.0243 0.025 0.1269
Schistosoma mansoni steroid dehydrogenase 0.0036 0.0021 0.0088
Trypanosoma brucei acetyl-CoA carboxylase 0.179 0.1958 1
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0056 0.0044 0.0433
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0526 0.0563 0.2373
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0032 0.0017 0.0206
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0036 0.0021 0.007
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0081 0.0071 0.0735
Loa Loa (eye worm) oxidoreductase 0.0036 0.0021 0.0109
Brugia malayi TAR-binding protein 0.0272 0.0282 0.149
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0081 0.0071 0.0585
Onchocerca volvulus Protein patched homolog 0.005 0.0037 0.0451
Echinococcus granulosus acetyl coenzyme A carboxylase 1 0.179 0.1958 0.8265
Brugia malayi hypothetical protein 0.0056 0.0044 0.023
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0056 0.0044 0.0539
Loa Loa (eye worm) PDE1B protein 0.0526 0.0563 0.2976
Schistosoma mansoni tar DNA-binding protein 0.0272 0.0282 0.1188
Mycobacterium ulcerans branched-chain alpha-keto acid dehydrogenase subunit E2 0.0063 0.0051 0.0678
Echinococcus multilocularis ubiquitin specific protease 41 0.0027 0.0011 0.001
Echinococcus multilocularis lysine specific demethylase 5A 0.0023 0.0007 0.0007
Schistosoma mansoni tar DNA-binding protein 0.0272 0.0282 0.1188
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0027 0.0012 0.0048
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0027 0.0012 0.0083
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0001 0.0002
Onchocerca volvulus 0.005 0.0037 0.0451
Mycobacterium ulcerans short chain dehydrogenase 0.0036 0.0021 0.0273
Schistosoma mansoni smad1 5 8 and 0.0022 0.0005 0.0022
Loa Loa (eye worm) hypothetical protein 0.0356 0.0375 0.1982
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0036 0.0021 0.0248
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0012
Plasmodium falciparum pyruvate kinase 0.0081 0.0071 0.0505
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.001
Trypanosoma cruzi glutamine dependent carbamoyl-phosphate synthase, putative 0.0154 0.0152 0.1258
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0081 0.0071 0.0949
Loa Loa (eye worm) hypothetical protein 0.0118 0.0112 0.0591
Loa Loa (eye worm) oxidoreductase 0.0036 0.0021 0.0109
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0012 0.0095
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0038 0.0023 0.0096
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0036 0.0021 0.0174
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0021 0.0174
Trypanosoma brucei unspecified product 0.0448 0.0477 0.2429
Plasmodium falciparum dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex 0.0063 0.0051 0.0361
Mycobacterium tuberculosis Conserved protein 0.0086 0.0077 0.0265
Echinococcus granulosus jumonji domain containing protein 0.0027 0.0011 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0008 0.009
Mycobacterium ulcerans acyl-CoA synthetase 0.0275 0.0285 0.3873
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0027 0.0011 0.009
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0021 0.0174
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0076 0.0065 0.0814
Plasmodium vivax patched family protein, putative 0.005 0.0037 0.0264
Plasmodium falciparum pyruvate kinase 2 0.0042 0.0028 0.0196
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0036 0.0021 0.007
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0036 0.0021 0.0273
Onchocerca volvulus 0.0036 0.0021 0.0248
Mycobacterium ulcerans beta-lactamase 0.0086 0.0077 0.1029
Loa Loa (eye worm) 6-phosphofructokinase 0.0151 0.0149 0.0784
Loa Loa (eye worm) hypothetical protein 0.0393 0.0416 0.2198
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0076 0.0065 0.0814
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0193 0.0195 0.1617
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0036 0.0022 0.0021
Trypanosoma brucei unspecified product 0.0061 0.0048 0.0241
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0206 0.0209 0.1104
Loa Loa (eye worm) hypothetical protein 0.005 0.0037 0.0194
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0038 0.0023 0.0023
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0027 0.0012 0.0054
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0048 0.0241
Echinococcus multilocularis protein dispatched 1 0.0407 0.043 0.043
Schistosoma mansoni bromodomain containing protein 0.0054 0.0041 0.0171
Schistosoma mansoni cpg binding protein 0.018 0.0181 0.0761
Echinococcus multilocularis tumor protein p63 0.0654 0.0704 0.0703
Trypanosoma brucei 3-methylcrotonyl-CoA carboxylase alpha subunit, putative 0.0682 0.0735 0.3747
Brugia malayi topoisomerase 0.0056 0.0044 0.023
Schistosoma mansoni thyroid hormone receptor 0.0175 0.0175 0.0737
Trichomonas vaginalis AGC family protein kinase 0.0036 0.0022 0.0262
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.008 0.007 0.0365
Echinococcus granulosus ubiquitin specific protease 41 0.0027 0.0011 0.0044
Schistosoma mansoni cpg binding protein 0.018 0.0181 0.0761
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0081 0.0071 0.007
Brugia malayi pyruvate kinase, muscle isozyme 0.0017 0.0001 0.0001
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0076 0.0065 0.0814
Loa Loa (eye worm) AGC/PKA protein kinase 0.0036 0.0022 0.0113
Echinococcus granulosus zinc finger protein 0.0023 0.0007 0.0028
Schistosoma mansoni cellular tumor antigen P53 0.0096 0.0087 0.0367
Onchocerca volvulus Huntingtin homolog 0.0118 0.0112 0.14
Brugia malayi conserved hypotetical protein 0.0038 0.0023 0.0121
Echinococcus granulosus hypothetical protein 0.0036 0.0021 0.0087
Loa Loa (eye worm) hypothetical protein 0.0125 0.0119 0.0628
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0042 0.0028 0.0116
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0036 0.0021 0.007
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0036 0.0021 0.007
Mycobacterium tuberculosis Probable oxidoreductase 0.0036 0.0021 0.007
Trypanosoma cruzi cruzipain precursor, putative 0.0044 0.003 0.0245
Trichomonas vaginalis rotamase, putative 0.0024 0.0008 0.0082
Brugia malayi AMP-binding enzyme family protein 0.0081 0.0071 0.0373
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0036 0.0021 0.007
Mycobacterium ulcerans short-chain type oxidoreductase 0.0036 0.0021 0.0273
Leishmania major quinonoid dihydropteridine reductase 0.0036 0.0021 0.0107
Entamoeba histolytica hypothetical protein 0.0301 0.0314 0.3455
Schistosoma mansoni nuclear receptor 0.0038 0.0023 0.0096
Echinococcus granulosus mixed lineage leukemia protein mll 0.0045 0.0032 0.0132
Giardia lamblia Hypothetical protein 0.0027 0.0012 0.0296
Trypanosoma cruzi 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase, putative 0.0063 0.0051 0.042
Schistosoma mansoni intermediate filament proteins 0.0022 0.0006 0.0022
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0107 0.01 0.0422
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide acyltransferase E2 component 0.0063 0.0051 0.0532
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0021 0.0111
Mycobacterium ulcerans aldehyde dehydrogenase 0.0229 0.0234 0.3179
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0027 0.0012 0.0047
Brugia malayi beta-lactamase family protein 0.0086 0.0077 0.0404
Schistosoma mansoni topbp1 0.0056 0.0044 0.0183
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.008 0.007 0.0069
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0027 0.0012 0.0134
Brugia malayi ecdysteroid receptor 0.008 0.007 0.0367
Brugia malayi Nuclear hormone receptor family member nhr-19 0.008 0.007 0.0367
Leishmania major 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0243 0.025 0.1273
Loa Loa (eye worm) oxidoreductase 0.0036 0.0021 0.0109
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0076 0.0065 0.0814
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0029 0.0014 0.0066
Brugia malayi Patched family protein 0.005 0.0037 0.0195
Toxoplasma gondii patched family protein 0.005 0.0037 0.0184
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.008 0.007 0.0291
Entamoeba histolytica PH domain containing protein kinase, putative 0.0036 0.0022 0.0186
Mycobacterium ulcerans ketoacyl reductase 0.0036 0.0021 0.0273
Schistosoma mansoni aldehyde dehydrogenase 0.0229 0.0234 0.0988
Mycobacterium ulcerans short chain dehydrogenase 0.0036 0.0021 0.0273
Mycobacterium tuberculosis Probable oxidoreductase 0.0036 0.0021 0.007
Onchocerca volvulus 0.0036 0.0021 0.0248
Schistosoma mansoni carbamoyl-phosphate synthetase 0.0154 0.0152 0.064
Echinococcus granulosus carbonyl reductase 1 0.0036 0.0021 0.0087
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0021 0.0111
Mycobacterium leprae Probable bifunctional protein acetyl-/propionyl-coenzyme A carboxylase, alpha chain AccA3 (BccP) 0.0682 0.0735 0.7768
Loa Loa (eye worm) hypothetical protein 0.0036 0.0021 0.0109
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0076 0.0065 0.0814
Brugia malayi Nuclear hormone receptor E75 0.0038 0.0023 0.0121
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.0036 0.0021 0.0212
Loa Loa (eye worm) MH2 domain-containing protein 0.0022 0.0005 0.0026
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0076 0.0065 0.0814
Schistosoma mansoni metabotropic glutamate receptor 0.0029 0.0014 0.0057
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0163 0.0161 0.0852
Schistosoma mansoni rotamase 0.0024 0.0008 0.0033
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0003 0.002
Toxoplasma gondii isocitrate dehydrogenase 0.0034 0.002 0.0094
Leishmania major quinonoid dihydropteridine reductase 0.0036 0.0021 0.0107
Echinococcus granulosus lamin dm0 0.0022 0.0006 0.0021
Leishmania major quinonoid dihydropteridine reductase 0.0036 0.0021 0.0107
Mycobacterium ulcerans ketoacyl reductase 0.0036 0.0021 0.0273
Schistosoma mansoni ran 0.0029 0.0014 0.0058
Mycobacterium ulcerans oxidoreductase 0.0036 0.0021 0.0273
Trichomonas vaginalis glucosylceramidase, putative 0.0163 0.0161 0.2028
Brugia malayi nuclear receptor RXR 0.0042 0.0028 0.0147
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0036 0.0021 0.0273
Leishmania major GTP-binding protein, putative 0.0029 0.0014 0.0071
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0091 0.0083 0.0421
Brugia malayi AMP-binding enzyme family protein 0.0275 0.0285 0.1508
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0076 0.0065 0.0814
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0076 0.0065 0.0814
Brugia malayi AMP-binding enzyme family protein 0.0081 0.0071 0.0373
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0038 0.0023 0.0096
Schistosoma mansoni microtubule-associated protein tau 0.17 0.1858 0.7842

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 6.3 uM Cytotoxicity against human MCF7 cells after 24 hrs by MTT assay ChEMBL. 22365913
IC50 (functional) = 11 uM Cytotoxicity against human KB cells after 24 hrs by MTT assay ChEMBL. 22365913
IC50 (functional) = 15.6 uM Cytotoxicity against human PC3 cells after 24 hrs by MTT assay ChEMBL. 22365913
Inhibition (functional) = 56.8 % Growth inhibition of human PC3 cells at 20 uM after 24 hrs by MTT assay ChEMBL. 22365913
Inhibition (functional) = 58.45 % Growth inhibition of human MCF7 cells at 20 uM after 24 hrs by MTT assay ChEMBL. 22365913
Inhibition (functional) = 68.54 % Growth inhibition of human KB cells at 20 uM after 24 hrs by MTT assay ChEMBL. 22365913

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 22365913

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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