Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | protein kinase c iota type | 0.0062 | 0.0663 | 0.0344 |
Loa Loa (eye worm) | hypothetical protein | 0.0245 | 0.7603 | 0.8366 |
Entamoeba histolytica | protein kinase , putative | 0.0126 | 0.3086 | 0.4491 |
Echinococcus granulosus | NDR protein kinase | 0.0062 | 0.0663 | 0.0344 |
Brugia malayi | serine/threonine protein kinase 6 | 0.0126 | 0.3086 | 0.3145 |
Entamoeba histolytica | protein kinase, putative | 0.0175 | 0.4961 | 0.7966 |
Trichomonas vaginalis | AGC family protein kinase | 0.0175 | 0.4961 | 0.5748 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0054 | 0.0366 | 0.0366 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0062 | 0.0663 | 0.0663 |
Onchocerca volvulus | 0.0054 | 0.0366 | 0.5 | |
Echinococcus multilocularis | rac serine:threonine kinase | 0.0117 | 0.2769 | 0.2778 |
Echinococcus multilocularis | ribosomal protein s6 kinase beta 1 | 0.0062 | 0.0663 | 0.0344 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0117 | 0.2769 | 0.3903 |
Trichomonas vaginalis | AGC family protein kinase | 0.0175 | 0.4961 | 0.5748 |
Onchocerca volvulus | 0.0054 | 0.0366 | 0.5 | |
Echinococcus multilocularis | voltage gated potassium channel | 0.0082 | 0.1414 | 0.1211 |
Schistosoma mansoni | hyperpolarization activated cyclic nucleotide-gated potassium channel | 0.0056 | 0.043 | 0.043 |
Echinococcus granulosus | Glutaredoxin protein 5 | 0.0113 | 0.261 | 0.2594 |
Leishmania major | protein kinase, putative | 0.0126 | 0.3086 | 0.5 |
Onchocerca volvulus | 0.0054 | 0.0366 | 0.5 | |
Trichomonas vaginalis | AGC family protein kinase | 0.0175 | 0.4961 | 0.5748 |
Trichomonas vaginalis | AGC family protein kinase | 0.0062 | 0.0663 | 0.0296 |
Brugia malayi | phosphoinositide-dependent protein kinase I | 0.0204 | 0.6058 | 0.658 |
Brugia malayi | protein kinase C II. | 0.0062 | 0.0663 | 0.0344 |
Echinococcus granulosus | cyclic nucleotide gated cation channel | 0.0056 | 0.043 | 0.0075 |
Entamoeba histolytica | protein kinase, putative | 0.0175 | 0.4961 | 0.7966 |
Onchocerca volvulus | 0.0054 | 0.0366 | 0.5 | |
Schistosoma mansoni | amine GPCR | 0.0054 | 0.0366 | 0.0366 |
Trichomonas vaginalis | serine/threonine-protein kinase sgk, putative | 0.0058 | 0.0505 | 0.0094 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.0062 | 0.0663 | 0.0344 |
Trichomonas vaginalis | AGC family protein kinase | 0.0062 | 0.0663 | 0.0296 |
Echinococcus multilocularis | cyclic nucleotide gated cation channel alpha 3 | 0.0056 | 0.043 | 0.0075 |
Entamoeba histolytica | protein kinase, putative | 0.0126 | 0.3086 | 0.4491 |
Loa Loa (eye worm) | AGC/RSK/RSK protein kinase | 0.0062 | 0.0663 | 0.0344 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0054 | 0.0366 | 0.0366 |
Echinococcus multilocularis | protein kinase c iota type | 0.0062 | 0.0663 | 0.0344 |
Schistosoma mansoni | neuropeptide receptor | 0.0054 | 0.0366 | 0.0366 |
Schistosoma mansoni | biogenic amine receptor | 0.0054 | 0.0366 | 0.0366 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0054 | 0.0366 | 0.0366 |
Trichomonas vaginalis | AGC family protein kinase | 0.0126 | 0.3086 | 0.3369 |
Echinococcus granulosus | aurora kinase A | 0.0126 | 0.3086 | 0.3145 |
Onchocerca volvulus | 0.0054 | 0.0366 | 0.5 | |
Brugia malayi | Protein kinase domain containing protein | 0.0062 | 0.0663 | 0.0344 |
Echinococcus multilocularis | cyclic nucleotide gated cation channel | 0.0056 | 0.043 | 0.0075 |
Schistosoma mansoni | hypothetical protein | 0.0054 | 0.0366 | 0.0366 |
Schistosoma mansoni | biogenic amine receptor | 0.0054 | 0.0366 | 0.0366 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0054 | 0.0366 | 0.0366 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0264 | 0.8312 | 1 |
Onchocerca volvulus | 0.0054 | 0.0366 | 0.5 | |
Schistosoma mansoni | voltage-gated potassium channel | 0.0082 | 0.1414 | 0.1414 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0054 | 0.0366 | 0.0366 |
Loa Loa (eye worm) | cyclic-nucleotide gated cation channel | 0.0056 | 0.043 | 0.0075 |
Schistosoma mansoni | amine GPCR | 0.0054 | 0.0366 | 0.0366 |
Loa Loa (eye worm) | AUR protein kinase | 0.0126 | 0.3086 | 0.3145 |
Schistosoma mansoni | serine/threonine kinase | 0.0062 | 0.0663 | 0.0663 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.0056 | 0.043 | 0.043 |
Echinococcus multilocularis | 3 phosphoinositide dependent protein kinase 1 | 0.0204 | 0.6058 | 0.658 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0062 | 0.0663 | 0.0344 |
Echinococcus granulosus | potassium:sodium hyperpolarization activated | 0.0056 | 0.043 | 0.0075 |
Echinococcus multilocularis | serine threonine protein kinase nrc serine threonine protein kinase gad | 0.0117 | 0.2769 | 0.2778 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.1414 | 0.1211 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.0175 | 0.4961 | 1 |
Echinococcus granulosus | protein kinase C gamma type | 0.0062 | 0.0663 | 0.0344 |
Trichomonas vaginalis | AGC family protein kinase | 0.0062 | 0.0663 | 0.0296 |
Echinococcus granulosus | protein kinase c epsilon type | 0.0062 | 0.0663 | 0.0344 |
Brugia malayi | Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog | 0.0082 | 0.1414 | 0.1211 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0054 | 0.0366 | 0.0366 |
Plasmodium falciparum | serine/threonine protein kinase, putative | 0.0126 | 0.3086 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0126 | 0.3086 | 0.3086 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0056 | 0.043 | 0.043 |
Loa Loa (eye worm) | AGC/PKN protein kinase | 0.0062 | 0.0663 | 0.0344 |
Trypanosoma cruzi | aurora B kinase, putative | 0.0126 | 0.3086 | 1 |
Onchocerca volvulus | 0.0054 | 0.0366 | 0.5 | |
Schistosoma mansoni | serine/threonine-protein kinase | 0.0117 | 0.2769 | 0.2769 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.0062 | 0.0663 | 0.0344 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0054 | 0.0366 | 0.0366 |
Loa Loa (eye worm) | AGC/AKT protein kinase | 0.0175 | 0.4961 | 0.5312 |
Echinococcus granulosus | cyclic nucleotide gated cation channel | 0.0056 | 0.043 | 0.0075 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0117 | 0.2769 | 0.3903 |
Echinococcus multilocularis | serine:threonine protein kinase 12 B | 0.0126 | 0.3086 | 0.3145 |
Schistosoma mansoni | opsin-like receptor | 0.0054 | 0.0366 | 0.0366 |
Loa Loa (eye worm) | AGC/RSK/MSK protein kinase | 0.0062 | 0.0663 | 0.0344 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0062 | 0.0663 | 0.0663 |
Schistosoma mansoni | amine GPCR | 0.0054 | 0.0366 | 0.0366 |
Echinococcus granulosus | cyclic nucleotide gated cation channel alpha 3 | 0.0056 | 0.043 | 0.0075 |
Trichomonas vaginalis | AGC family protein kinase | 0.0204 | 0.6058 | 0.714 |
Echinococcus granulosus | serine:threonine protein kinase 12 B | 0.0126 | 0.3086 | 0.3145 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0054 | 0.0366 | 0.0366 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.0117 | 0.2769 | 0.2769 |
Schistosoma mansoni | opsin-like receptor | 0.0054 | 0.0366 | 0.0366 |
Trichomonas vaginalis | AGC family protein kinase | 0.0126 | 0.3086 | 0.3369 |
Entamoeba histolytica | protein kinase, putative | 0.0126 | 0.3086 | 0.4491 |
Onchocerca volvulus | 0.0054 | 0.0366 | 0.5 | |
Trichomonas vaginalis | AGC family protein kinase | 0.0204 | 0.6058 | 0.714 |
Schistosoma mansoni | hypothetical protein | 0.0054 | 0.0366 | 0.0366 |
Onchocerca volvulus | 0.0054 | 0.0366 | 0.5 | |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0054 | 0.0366 | 0.0366 |
Schistosoma mansoni | hyperpolarization activated cyclic nucleotide-gated potassium channel | 0.0056 | 0.043 | 0.043 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0282 | 0.9017 | 1 |
Onchocerca volvulus | 0.0054 | 0.0366 | 0.5 | |
Echinococcus granulosus | nervana 2 | 0.0113 | 0.261 | 0.2594 |
Echinococcus multilocularis | Glutaredoxin protein 5 | 0.0113 | 0.261 | 0.2594 |
Onchocerca volvulus | 0.0054 | 0.0366 | 0.5 | |
Loa Loa (eye worm) | AGC/RSK/P70 protein kinase | 0.0175 | 0.4961 | 0.5312 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.0113 | 0.261 | 0.2594 |
Echinococcus granulosus | ribosomal protein S6 kinase alpha 3 | 0.0062 | 0.0663 | 0.0344 |
Trichomonas vaginalis | AGC family protein kinase | 0.0175 | 0.4961 | 0.5748 |
Entamoeba histolytica | serine/threonine- protein kinase 6, putative | 0.0126 | 0.3086 | 0.4491 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0054 | 0.0366 | 0.0366 |
Echinococcus granulosus | serine/threonine protein kinase | 0.0117 | 0.2769 | 0.2778 |
Onchocerca volvulus | 0.0054 | 0.0366 | 0.5 | |
Brugia malayi | p70 ribosomal S6 kinase beta | 0.0175 | 0.4961 | 0.5312 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0082 | 0.1414 | 0.1414 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.0056 | 0.043 | 0.043 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0054 | 0.0366 | 0.0366 |
Echinococcus granulosus | ribosomal protein s6 kinase beta 1 | 0.0062 | 0.0663 | 0.0344 |
Echinococcus multilocularis | serine:threonine protein kinase 38 | 0.0062 | 0.0663 | 0.0344 |
Schistosoma mansoni | protein kinase | 0.0126 | 0.3086 | 0.3086 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0282 | 0.9017 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.0054 | 0.0366 | 0.0366 |
Onchocerca volvulus | 0.0054 | 0.0366 | 0.5 | |
Loa Loa (eye worm) | AGC/DMPK/GEK protein kinase | 0.0062 | 0.0663 | 0.0344 |
Schistosoma mansoni | amine GPCR | 0.0054 | 0.0366 | 0.0366 |
Echinococcus multilocularis | protein kinase c epsilon type | 0.0062 | 0.0663 | 0.0344 |
Echinococcus multilocularis | hyperpolarization activated cyclic | 0.0056 | 0.043 | 0.0075 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0054 | 0.0366 | 0.0366 |
Brugia malayi | Protein kinase domain containing protein | 0.0175 | 0.4961 | 0.5312 |
Echinococcus multilocularis | hyperpolarization activated cyclic | 0.0056 | 0.043 | 0.0075 |
Schistosoma mansoni | myosin xvIII | 0.0054 | 0.0366 | 0.0366 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0054 | 0.0366 | 0.0366 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0054 | 0.0366 | 0.0366 |
Schistosoma mansoni | neuropeptide receptor | 0.0054 | 0.0366 | 0.0366 |
Onchocerca volvulus | 0.0054 | 0.0366 | 0.5 | |
Loa Loa (eye worm) | AUR protein kinase | 0.0126 | 0.3086 | 0.3145 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.0056 | 0.043 | 0.043 |
Trichomonas vaginalis | AGC family protein kinase | 0.0175 | 0.4961 | 0.5748 |
Trichomonas vaginalis | AGC family protein kinase | 0.0175 | 0.4961 | 0.5748 |
Echinococcus multilocularis | ribosomal protein S6 kinase alpha 3 | 0.0062 | 0.0663 | 0.0344 |
Schistosoma mansoni | adenoreceptor | 0.0054 | 0.0366 | 0.0366 |
Loa Loa (eye worm) | AGC/PDK1 protein kinase | 0.0204 | 0.6058 | 0.658 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0054 | 0.0366 | 0.0366 |
Schistosoma mansoni | opsin-like receptor | 0.0054 | 0.0366 | 0.0366 |
Entamoeba histolytica | serine/threonine protein kinase 6, putative | 0.0126 | 0.3086 | 0.4491 |
Echinococcus granulosus | hyperpolarization activated cyclic | 0.0056 | 0.043 | 0.0075 |
Echinococcus granulosus | voltage gated potassium channel | 0.0082 | 0.1414 | 0.1211 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0054 | 0.0366 | 0.0366 |
Loa Loa (eye worm) | AUR protein kinase | 0.0126 | 0.3086 | 0.3145 |
Echinococcus granulosus | Protein kinase C brain isozyme | 0.0062 | 0.0663 | 0.0344 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0054 | 0.0366 | 0.0366 |
Brugia malayi | Protein kinase domain containing protein | 0.0204 | 0.6058 | 0.658 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0204 | 0.6058 | 0.6058 |
Entamoeba histolytica | serine/threonine- protein kinase 6 , putative | 0.0126 | 0.3086 | 0.4491 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0082 | 0.1414 | 0.1211 |
Trichomonas vaginalis | AGC family protein kinase | 0.0175 | 0.4961 | 0.5748 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0062 | 0.0663 | 0.0663 |
Echinococcus multilocularis | potassium:sodium hyperpolarization activated | 0.0056 | 0.043 | 0.0075 |
Plasmodium vivax | serine/threonine protein kinase 6, putative | 0.0126 | 0.3086 | 1 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0054 | 0.0366 | 0.0366 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0062 | 0.0663 | 0.0663 |
Schistosoma mansoni | histamine h1 receptor | 0.0054 | 0.0366 | 0.0366 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0054 | 0.0366 | 0.5 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0282 | 0.9017 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0062 | 0.0663 | 0.0663 |
Trichomonas vaginalis | AGC family protein kinase | 0.0062 | 0.0663 | 0.0296 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0062 | 0.0663 | 0.0344 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0054 | 0.0366 | 0.0366 |
Brugia malayi | serine/threonine-protein kinase 6 | 0.0126 | 0.3086 | 0.3145 |
Brugia malayi | Hr1 repeat family protein | 0.0062 | 0.0663 | 0.0344 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0282 | 0.9017 | 1 |
Loa Loa (eye worm) | cyclic-nucleotide gated cation channel | 0.0056 | 0.043 | 0.0075 |
Echinococcus granulosus | Ribosomal protein S6 kinase beta 2 | 0.0062 | 0.0663 | 0.0344 |
Echinococcus multilocularis | aurora kinase A | 0.0126 | 0.3086 | 0.3145 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0126 | 0.3086 | 0.4491 |
Echinococcus multilocularis | nervana 2 | 0.0113 | 0.261 | 0.2594 |
Onchocerca volvulus | 0.0054 | 0.0366 | 0.5 | |
Brugia malayi | Cyclic-nucleotide gated cation channel | 0.0056 | 0.043 | 0.0075 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0054 | 0.0366 | 0.0366 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0054 | 0.0366 | 0.0366 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0054 | 0.0366 | 0.0366 |
Toxoplasma gondii | AGC kinase | 0.0175 | 0.4961 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0054 | 0.0366 | 0.0366 |
Echinococcus multilocularis | Ribosomal protein S6 kinase beta 2 | 0.0062 | 0.0663 | 0.0344 |
Schistosoma mansoni | amine GPCR | 0.0054 | 0.0366 | 0.0366 |
Onchocerca volvulus | 0.0054 | 0.0366 | 0.5 | |
Schistosoma mansoni | serine/threonine protein kinase | 0.0062 | 0.0663 | 0.0663 |
Schistosoma mansoni | biogenic amine receptor | 0.0054 | 0.0366 | 0.0366 |
Onchocerca volvulus | 0.0054 | 0.0366 | 0.5 | |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0264 | 0.8312 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0062 | 0.0663 | 0.0663 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0054 | 0.0366 | 0.0366 |
Brugia malayi | Protein kinase domain containing protein | 0.0062 | 0.0663 | 0.0344 |
Trichomonas vaginalis | AGC family protein kinase | 0.0126 | 0.3086 | 0.3369 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0082 | 0.1414 | 0.1211 |
Trichomonas vaginalis | AGC family protein kinase | 0.0126 | 0.3086 | 0.3369 |
Loa Loa (eye worm) | AGC/PDK1 protein kinase | 0.0204 | 0.6058 | 0.658 |
Giardia lamblia | Aurora kinase | 0.0126 | 0.3086 | 1 |
Entamoeba histolytica | protein kinase 2, putative | 0.0117 | 0.2769 | 0.3903 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0054 | 0.0366 | 0.0366 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0054 | 0.0366 | 0.0366 |
Echinococcus granulosus | serine:threonine protein kinase N2 | 0.0062 | 0.0663 | 0.0344 |
Entamoeba histolytica | protein kinase, putative | 0.0175 | 0.4961 | 0.7966 |
Loa Loa (eye worm) | AGC/NDR protein kinase | 0.0062 | 0.0663 | 0.0344 |
Echinococcus granulosus | serine threonine protein kinase nrc | 0.0117 | 0.2769 | 0.2778 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.0663 | 0.0344 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0054 | 0.0366 | 0.0366 |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase | 0.0117 | 0.2769 | 0.2778 |
Schistosoma mansoni | neuropeptide receptor | 0.0054 | 0.0366 | 0.0366 |
Entamoeba histolytica | protein kinase, putative | 0.0204 | 0.6058 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0204 | 0.6058 | 0.714 |
Schistosoma mansoni | hypothetical protein | 0.0054 | 0.0366 | 0.0366 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0054 | 0.0366 | 0.0366 |
Schistosoma mansoni | hypothetical protein | 0.0054 | 0.0366 | 0.0366 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0054 | 0.0366 | 0.0366 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0054 | 0.0366 | 0.5 |
Echinococcus granulosus | 3-phosphoinositide-dependent protein kinase 1 | 0.0204 | 0.6058 | 0.658 |
Echinococcus granulosus | nervana 2 | 0.0113 | 0.261 | 0.2594 |
Brugia malayi | serine/threonine kinase 12 | 0.0126 | 0.3086 | 0.3145 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.043 | 0.0075 |
Echinococcus granulosus | hyperpolarization activated cyclic | 0.0056 | 0.043 | 0.0075 |
Echinococcus multilocularis | nervana 2 | 0.0113 | 0.261 | 0.2594 |
Schistosoma mansoni | atypical protein kinase C | 0.0062 | 0.0663 | 0.0663 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.0113 | 0.261 | 0.2594 |
Echinococcus multilocularis | serine threonine protein kinase | 0.0062 | 0.0663 | 0.0344 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI50 (functional) | -5.841 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.815 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.671 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.531 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.467 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.385 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.348 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.028 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.929 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.826 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.779 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.