Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | neuroglian | 0.0027 | 0.043 | 0.0771 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0201 | 0.5576 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0267 | 0.0267 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0201 | 0.5576 | 0.5 |
Echinococcus granulosus | twitchin | 0.0029 | 0.0484 | 0.0868 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0201 | 0.5576 | 0.5 |
Echinococcus granulosus | Immunoglobulin | 0.0022 | 0.0267 | 0.0479 |
Echinococcus multilocularis | Immunoglobulin | 0.0022 | 0.0267 | 0.0479 |
Schistosoma mansoni | nephrin | 0.0027 | 0.043 | 0.0771 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0267 | 0.0267 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0201 | 0.5576 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0267 | 0.0267 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0201 | 0.5576 | 0.5 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0201 | 0.5576 | 0.5576 |
Onchocerca volvulus | 0.0321 | 0.9096 | 0.9763 | |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0201 | 0.5576 | 0.5 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0201 | 0.5576 | 1 |
Echinococcus multilocularis | roundabout 2 | 0.0034 | 0.0638 | 0.1145 |
Brugia malayi | Fibronectin type III domain containing protein | 0.0022 | 0.0267 | 0.0267 |
Echinococcus granulosus | neurotracting:lsamp:neurotrimin:obcam | 0.0029 | 0.0475 | 0.0852 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0201 | 0.5576 | 0.5 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0201 | 0.5576 | 0.5 |
Echinococcus granulosus | roundabout 2 | 0.0034 | 0.0638 | 0.1145 |
Echinococcus granulosus | defective proboscis extension response | 0.0022 | 0.0267 | 0.0479 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0201 | 0.5576 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0201 | 0.5576 | 0.5 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0201 | 0.5576 | 1 |
Echinococcus multilocularis | Immunoglobulin | 0.0022 | 0.0267 | 0.0479 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0201 | 0.5576 | 0.5 |
Loa Loa (eye worm) | CAMK/MLCK protein kinase | 0.0014 | 0.0054 | 0.0054 |
Onchocerca volvulus | Tyrosine kinase homolog | 0.0328 | 0.9317 | 1 |
Echinococcus multilocularis | basement membrane specific heparan sulfate | 0.0022 | 0.0267 | 0.0479 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0267 | 0.0267 |
Brugia malayi | MAP kinase sur-1 | 0.0201 | 0.5576 | 0.5576 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0201 | 0.5576 | 1 |
Schistosoma mansoni | vesicular amine transporter | 0.0022 | 0.0267 | 0.0479 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0267 | 0.0267 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0201 | 0.5576 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0267 | 0.0267 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0022 | 0.0267 | 0.0267 |
Schistosoma mansoni | cell adhesion molecule | 0.0029 | 0.0475 | 0.0852 |
Schistosoma mansoni | tyrosine kinase | 0.0015 | 0.0058 | 0.0104 |
Trypanosoma brucei | protein kinase, putative | 0.0201 | 0.5576 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0638 | 0.0638 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0638 | 0.0638 |
Schistosoma mansoni | Neurotrimin precursor (hNT) | 0.0022 | 0.0267 | 0.0479 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0475 | 0.0475 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0201 | 0.5576 | 1 |
Echinococcus multilocularis | neuroglian | 0.0027 | 0.043 | 0.0771 |
Schistosoma mansoni | defective proboscis extension response (dpr)-related | 0.0022 | 0.0267 | 0.0479 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0201 | 0.5576 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0267 | 0.0267 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0201 | 0.5576 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.