Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | pax transcription factor protein 2 | 0.0291 | 0.2956 | 0.5645 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.002 | 0.0037 | 0.0128 |
Echinococcus multilocularis | heat shock protein 90 | 0.0055 | 0.042 | 0.0384 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0166 | 0.0299 |
Plasmodium falciparum | heat shock protein 90 | 0.0055 | 0.042 | 0.1976 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.006 | 0.0473 | 0.084 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0055 | 0.0419 | 0.0383 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0115 | 0.1066 | 0.1983 |
Echinococcus granulosus | dual specificity | 0.0108 | 0.0982 | 0.1822 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0145 | 0.1384 | 1 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0502 | 0.5228 | 1 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0055 | 0.042 | 0.0738 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.003 | 0.0152 | 0.0682 |
Echinococcus multilocularis | muscleblind protein | 0.0159 | 0.154 | 0.1509 |
Trypanosoma brucei | trypanothione reductase | 0.0057 | 0.0439 | 0.0775 |
Trichomonas vaginalis | heat shock protein, putative | 0.0055 | 0.042 | 0.0738 |
Plasmodium vivax | heat shock protein 86, putative | 0.0055 | 0.042 | 0.1976 |
Echinococcus multilocularis | heat shock protein 90 | 0.0047 | 0.0334 | 0.0298 |
Schistosoma mansoni | heat shock protein | 0.0055 | 0.042 | 0.0738 |
Toxoplasma gondii | thioredoxin reductase | 0.0057 | 0.0439 | 0.0775 |
Schistosoma mansoni | lamin | 0.0063 | 0.0497 | 0.0887 |
Entamoeba histolytica | hexokinase 2 | 0.0096 | 0.086 | 0.8654 |
Brugia malayi | TAR-binding protein | 0.0076 | 0.0648 | 0.118 |
Loa Loa (eye worm) | glutathione reductase | 0.0057 | 0.0439 | 0.0821 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.154 | 0.2931 |
Echinococcus multilocularis | heat shock protein 75 kDa, mitochondrial | 0.0037 | 0.022 | 0.0184 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.003 | 0.0152 | 0.0221 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0145 | 0.1384 | 0.5155 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0043 | 0.0283 | 0.0474 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0042 | 0.0271 | 0.1011 |
Mycobacterium ulcerans | lipase LipD | 0.0042 | 0.0271 | 0.1443 |
Echinococcus granulosus | geminin | 0.0205 | 0.2029 | 0.3837 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0073 | 0.0349 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0042 | 0.0271 | 0.0452 |
Brugia malayi | Pre-SET motif family protein | 0.0222 | 0.2215 | 0.4197 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.002 | 0.0037 | 0.0128 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0144 | 0.1377 | 0.262 |
Onchocerca volvulus | 0.006 | 0.0474 | 0.1389 | |
Schistosoma mansoni | jumonji domain containing protein | 0.0092 | 0.0811 | 0.1491 |
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 0.0648 | 0.1177 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0073 | 0.0121 |
Brugia malayi | intermediate filament protein | 0.0063 | 0.0497 | 0.089 |
Trichomonas vaginalis | heat shock protein, putative | 0.0052 | 0.0383 | 0.0667 |
Plasmodium vivax | endoplasmin, putative | 0.0055 | 0.042 | 0.1976 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0073 | 0.0073 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.042 | 0.0738 |
Plasmodium vivax | SET domain protein, putative | 0.0032 | 0.0166 | 0.0754 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0076 | 0.0648 | 0.1222 |
Loa Loa (eye worm) | TAR-binding protein | 0.0076 | 0.0648 | 0.1222 |
Leishmania major | hypothetical protein, conserved | 0.0042 | 0.0271 | 0.0452 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0047 | 0.0334 | 0.0572 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.013 | 0.1227 | 0.8805 |
Onchocerca volvulus | 0.0096 | 0.086 | 0.2729 | |
Schistosoma mansoni | lamin | 0.0063 | 0.0497 | 0.0887 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0043 | 0.0283 | 0.0247 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0474 | 0.0889 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0352 | 0.3614 | 0.689 |
Onchocerca volvulus | 0.0042 | 0.0271 | 0.0687 | |
Onchocerca volvulus | Alhambra homolog | 0.0035 | 0.0203 | 0.0449 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0153 | 0.0274 |
Plasmodium falciparum | thioredoxin reductase | 0.002 | 0.0037 | 0.0128 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.042 | 0.0738 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0153 | 0.0274 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0055 | 0.0419 | 0.0736 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.042 | 0.0738 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0055 | 0.042 | 0.0738 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0042 | 0.0271 | 0.0452 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.042 | 0.0738 |
Plasmodium vivax | glutathione reductase, putative | 0.0057 | 0.0439 | 0.2067 |
Loa Loa (eye worm) | heat shock protein 75 | 0.0037 | 0.022 | 0.0401 |
Onchocerca volvulus | Heat shock protein 75 kDa, mitochondrial homolog | 0.0037 | 0.022 | 0.0507 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0032 | 0.0166 | 0.025 |
Trypanosoma brucei | Heat shock protein 83, putative | 0.0055 | 0.042 | 0.0738 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0502 | 0.5228 | 1 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0502 | 0.5228 | 1 |
Echinococcus granulosus | heat shock protein | 0.0055 | 0.042 | 0.0738 |
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 0.0648 | 0.1177 |
Echinococcus multilocularis | hexokinase | 0.0096 | 0.086 | 0.0826 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0149 | 0.0265 |
Onchocerca volvulus | 0.0032 | 0.0166 | 0.0323 | |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0042 | 0.0271 | 0.0452 |
Treponema pallidum | hexokinase (hxk) | 0.0096 | 0.086 | 1 |
Plasmodium falciparum | glutathione reductase | 0.002 | 0.0037 | 0.0128 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0043 | 0.0283 | 0.0474 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.013 | 0.1227 | 0.4571 |
Trichomonas vaginalis | endoplasmin, putative | 0.004 | 0.0256 | 0.0423 |
Echinococcus granulosus | jumonji domain containing protein | 0.0049 | 0.0351 | 0.0606 |
Brugia malayi | Endoplasmin precursor | 0.0055 | 0.042 | 0.0741 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0271 | 0.05 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.003 | 0.0152 | 0.0221 |
Treponema pallidum | heat shock protein 90 | 0.0052 | 0.0383 | 0.4208 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0108 | 0.0982 | 0.1822 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0271 | 0.05 |
Plasmodium falciparum | thioredoxin reductase | 0.0057 | 0.0439 | 0.2067 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0055 | 0.0419 | 0.0736 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0035 | 0.0203 | 0.032 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0032 | 0.0166 | 0.025 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0136 | 0.0242 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0144 | 0.1377 | 0.262 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0076 | 0.0648 | 0.118 |
Loa Loa (eye worm) | intermediate filament protein | 0.0063 | 0.0497 | 0.0934 |
Trypanosoma brucei | heat shock protein, putative | 0.0055 | 0.042 | 0.0738 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0073 | 0.0607 | 0.1144 |
Toxoplasma gondii | hexokinase | 0.0096 | 0.086 | 0.1586 |
Mycobacterium tuberculosis | Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) | 0.0052 | 0.0383 | 0.1427 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.042 | 0.0738 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0042 | 0.0271 | 0.1011 |
Plasmodium falciparum | heat shock protein 90, putative | 0.0032 | 0.017 | 0.0771 |
Trypanosoma brucei | heat shock protein, putative | 0.0055 | 0.042 | 0.0738 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0073 | 0.0121 |
Brugia malayi | MAP kinase sur-1 | 0.0502 | 0.5228 | 1 |
Echinococcus granulosus | hexokinase | 0.0096 | 0.086 | 0.1586 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.042 | 0.0738 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0352 | 0.3614 | 0.689 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0055 | 0.042 | 0.0738 |
Brugia malayi | Muscleblind-like protein | 0.0159 | 0.154 | 0.2897 |
Echinococcus multilocularis | peregrin | 0.0035 | 0.0203 | 0.0167 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0145 | 0.1384 | 0.5155 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.003 | 0.0152 | 0.0221 |
Brugia malayi | beta-lactamase family protein | 0.0042 | 0.0271 | 0.0455 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0352 | 0.3614 | 0.689 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0063 | 0.0497 | 0.089 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0042 | 0.0271 | 0.0452 |
Brugia malayi | Hexokinase family protein | 0.003 | 0.0144 | 0.021 |
Giardia lamblia | PHD finger protein 15 | 0.0035 | 0.0203 | 0.032 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.003 | 0.0152 | 0.0682 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0055 | 0.042 | 0.0738 |
Plasmodium falciparum | heat shock protein 90, putative | 0.021 | 0.2084 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0055 | 0.0419 | 0.0736 |
Echinococcus granulosus | intermediate filament protein | 0.0063 | 0.0497 | 0.0887 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.042 | 0.0738 |
Echinococcus granulosus | heat shock protein 90 | 0.0047 | 0.0334 | 0.0572 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0159 | 0.154 | 0.1509 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.003 | 0.0152 | 0.0221 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0057 | 0.0439 | 0.0775 |
Brugia malayi | MH2 domain containing protein | 0.0144 | 0.1377 | 0.2584 |
Echinococcus multilocularis | hexokinase | 0.0096 | 0.086 | 0.0826 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0073 | 0.0349 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0023 | 0.0073 | 0.0273 |
Echinococcus granulosus | hexokinase | 0.0096 | 0.086 | 0.1586 |
Loa Loa (eye worm) | endoplasmin | 0.0055 | 0.042 | 0.0785 |
Schistosoma mansoni | endoplasmin | 0.0055 | 0.042 | 0.0738 |
Onchocerca volvulus | 0.0042 | 0.0271 | 0.0687 | |
Toxoplasma gondii | heat shock protein 90, putative | 0.0055 | 0.042 | 0.0738 |
Brugia malayi | Hsp90 protein | 0.0037 | 0.022 | 0.0355 |
Plasmodium falciparum | endoplasmin, putative | 0.004 | 0.0256 | 0.1187 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.0166 | 0.025 |
Trypanosoma brucei | heat shock protein, putative | 0.0055 | 0.042 | 0.0738 |
Onchocerca volvulus | 0.0096 | 0.086 | 0.2729 | |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0166 | 0.1617 | 0.3044 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0271 | 0.05 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.002 | 0.0037 | 0.0003 |
Brugia malayi | Pax transcription factor protein 2 | 0.0291 | 0.2956 | 0.5624 |
Echinococcus granulosus | lamin dm0 | 0.0063 | 0.0497 | 0.0887 |
Echinococcus granulosus | heat shock protein 75 kDa mitochondrial | 0.0037 | 0.022 | 0.0352 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0042 | 0.0271 | 0.1011 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0043 | 0.0283 | 0.0522 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0035 | 0.0203 | 0.032 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.042 | 0.0738 |
Toxoplasma gondii | Hsp90 domain-containing protein | 0.021 | 0.2084 | 0.3943 |
Echinococcus multilocularis | lamin dm0 | 0.0063 | 0.0497 | 0.0462 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.053 | 0.0997 |
Onchocerca volvulus | 0.0164 | 0.1593 | 0.5274 | |
Wolbachia endosymbiont of Brugia malayi | heat shock protein 90 | 0.0052 | 0.0383 | 1 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0502 | 0.5228 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0076 | 0.0648 | 0.1222 |
Trypanosoma brucei | heat shock protein, putative | 0.0055 | 0.042 | 0.0738 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0108 | 0.0982 | 0.1822 |
Loa Loa (eye worm) | heat shock protein 90 | 0.0055 | 0.042 | 0.0785 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0115 | 0.1066 | 0.1033 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0023 | 0.0073 | 0.0273 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.013 | 0.1227 | 0.4571 |
Echinococcus granulosus | hexokinase | 0.0096 | 0.086 | 0.1586 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.042 | 0.0738 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.002 | 0.0037 | 0.0147 |
Plasmodium vivax | heat shock protein 90, putative | 0.0037 | 0.022 | 0.101 |
Echinococcus granulosus | endoplasmin | 0.0052 | 0.0383 | 0.0667 |
Onchocerca volvulus | 0.0096 | 0.086 | 0.2729 | |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.002 | 0.0037 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0055 | 0.0419 | 0.0383 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0073 | 0.0073 |
Plasmodium falciparum | hexokinase | 0.0096 | 0.086 | 0.4099 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0055 | 0.042 | 0.0738 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0063 | 0.0497 | 0.0934 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.0166 | 0.025 |
Trypanosoma cruzi | Heat shock protein 83, putative | 0.0055 | 0.042 | 0.0738 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.002 | 0.0037 | 0.0128 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0057 | 0.0439 | 0.0821 |
Echinococcus multilocularis | hexokinase type 2 | 0.0096 | 0.086 | 0.0826 |
Brugia malayi | glutathione reductase | 0.0057 | 0.0439 | 0.0777 |
Echinococcus multilocularis | heat shock protein | 0.0055 | 0.042 | 0.0384 |
Trypanosoma brucei | heat shock protein, putative | 0.0055 | 0.042 | 0.0738 |
Echinococcus granulosus | heat shock protein 90 | 0.0055 | 0.042 | 0.0738 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0042 | 0.0271 | 0.05 |
Leishmania major | hypothetical protein, conserved | 0.003 | 0.0152 | 0.0221 |
Echinococcus granulosus | muscleblind protein | 0.0159 | 0.154 | 0.2895 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0042 | 0.0271 | 0.0452 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0042 | 0.0271 | 0.0452 |
Entamoeba histolytica | hexokinase 1 | 0.0096 | 0.086 | 0.8654 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.042 | 0.0738 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0049 | 0.0356 | 0.0616 |
Brugia malayi | heat shock protein 90 | 0.0055 | 0.042 | 0.0741 |
Entamoeba histolytica | 90 kDa heat shock protein, putative | 0.0037 | 0.022 | 0.1609 |
Mycobacterium leprae | Probable lipase LipE | 0.0042 | 0.0271 | 0.151 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0222 | 0.2215 | 0.4225 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0042 | 0.0271 | 0.0452 |
Trypanosoma brucei | hexokinase | 0.0096 | 0.086 | 0.1586 |
Brugia malayi | hexokinase | 0.0096 | 0.086 | 0.1588 |
Schistosoma mansoni | hypothetical protein | 0.0205 | 0.2029 | 0.3837 |
Trypanosoma cruzi | heat shock protein, putative | 0.0037 | 0.022 | 0.0352 |
Leishmania major | lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative | 0.0052 | 0.0383 | 0.0667 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0042 | 0.0271 | 0.0452 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.013 | 0.1227 | 0.4571 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0055 | 0.042 | 0.3811 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0042 | 0.0271 | 0.0235 |
Toxoplasma gondii | ABC1 family protein | 0.0042 | 0.0271 | 0.0452 |
Echinococcus multilocularis | dual specificity | 0.0108 | 0.0982 | 0.0949 |
Brugia malayi | jmjC domain containing protein | 0.0115 | 0.1066 | 0.1985 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.1593 | 0.3034 |
Echinococcus multilocularis | endoplasmin | 0.0052 | 0.0383 | 0.0348 |
Loa Loa (eye worm) | hexokinase type II | 0.0096 | 0.086 | 0.1629 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0265 | 0.2685 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.042 | 0.0738 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0271 | 0.05 |
Loa Loa (eye worm) | beta-lactamase | 0.0042 | 0.0271 | 0.05 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0033 | 0.0184 | 0.0287 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0042 | 0.0271 | 0.0452 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0031 | 0.0154 | 0.0226 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0502 | 0.5228 | 1 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0049 | 0.0356 | 0.0616 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.042 | 0.0738 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.042 | 0.0738 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0185 | 0.182 | 0.6779 |
Plasmodium falciparum | glutathione reductase | 0.0057 | 0.0439 | 0.2067 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0057 | 0.0439 | 0.0404 |
Loa Loa (eye worm) | CMGC/DYRK/DYRK1 protein kinase | 0.0108 | 0.0982 | 0.1863 |
Schistosoma mansoni | heat shock protein | 0.0055 | 0.042 | 0.0738 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0203 | 0.0369 |
Mycobacterium ulcerans | hypothetical protein | 0.0185 | 0.182 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0076 | 0.0648 | 0.0613 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0203 | 0.032 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.154 | 0.2931 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0502 | 0.5228 | 1 |
Brugia malayi | hypothetical protein | 0.003 | 0.0152 | 0.0224 |
Brugia malayi | Bromodomain containing protein | 0.0035 | 0.0203 | 0.0323 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.0928 | 0.1759 |
Mycobacterium leprae | PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) | 0.0052 | 0.0383 | 0.2364 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0502 | 0.5228 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0073 | 0.0349 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.0928 | 0.1759 |
Onchocerca volvulus | 0.0291 | 0.2956 | 1 | |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0502 | 0.5228 | 1 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0502 | 0.5228 | 1 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0042 | 0.0271 | 0.1011 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0073 | 0.0121 |
Mycobacterium ulcerans | hypothetical protein | 0.0042 | 0.0271 | 0.1443 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0502 | 0.5228 | 1 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0502 | 0.5228 | 1 |
Mycobacterium tuberculosis | Probable reductase | 0.013 | 0.1227 | 0.4571 |
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 0.0648 | 0.1177 |
Plasmodium vivax | hypothetical protein, conserved | 0.0035 | 0.0203 | 0.0929 |
Schistosoma mansoni | heat shock protein | 0.0037 | 0.022 | 0.0352 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.003 | 0.0149 | 0.0216 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0271 | 0.05 |
Echinococcus multilocularis | geminin | 0.0205 | 0.2029 | 0.1999 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0502 | 0.5228 | 1 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0049 | 0.0356 | 0.0616 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0023 | 0.0073 | 0.0349 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0032 | 0.0166 | 0.013 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0055 | 0.0419 | 0.0736 |
Brugia malayi | hexokinase type II | 0.0031 | 0.0153 | 0.0227 |
Loa Loa (eye worm) | hexokinase | 0.006 | 0.0474 | 0.0888 |
Trypanosoma cruzi | hexokinase, putative | 0.0096 | 0.086 | 0.1586 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0047 | 0.0334 | 0.0572 |
Toxoplasma gondii | heat shock protein HSP90 | 0.0055 | 0.042 | 0.0738 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.002 | 0.0037 | 0.0128 |
Entamoeba histolytica | hypothetical protein | 0.0108 | 0.0982 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0073 | 0.0073 |
Echinococcus multilocularis | lamin | 0.0063 | 0.0497 | 0.0462 |
Brugia malayi | Thioredoxin reductase | 0.0057 | 0.0439 | 0.0777 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0352 | 0.3614 | 0.689 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0073 | 0.0071 |
Onchocerca volvulus | 0.0253 | 0.2545 | 0.8576 | |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.013 | 0.1227 | 0.4571 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0073 | 0.0071 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.042 | 0.0738 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0033 | 0.0184 | 0.0334 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0055 | 0.042 | 0.0738 |
Trypanosoma brucei | heat shock protein, putative | 0.0055 | 0.042 | 0.0738 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0502 | 0.5228 | 0.5211 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0035 | 0.0203 | 0.032 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0049 | 0.0356 | 0.0616 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0502 | 0.5228 | 1 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0023 | 0.0073 | 0.007 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.002 | 0.0037 | 0.0137 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.002 | 0.0037 | 0.0147 |
Schistosoma mansoni | endoplasmin | 0.0055 | 0.042 | 0.0738 |
Onchocerca volvulus | 0.0063 | 0.0497 | 0.1471 | |
Loa Loa (eye worm) | PHD-finger family protein | 0.0035 | 0.0203 | 0.0369 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0502 | 0.5228 | 1 |
Leishmania major | hexokinase, putative | 0.0096 | 0.086 | 0.1586 |
Giardia lamblia | Grp94/Hsp90 | 0.0052 | 0.0383 | 0.0667 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0108 | 0.0982 | 0.1822 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.002 | 0.0037 | 0.0147 |
Trypanosoma brucei | heat shock protein, putative | 0.0055 | 0.042 | 0.0738 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0485 | 0.091 |
Brugia malayi | beta-lactamase family protein | 0.0042 | 0.0271 | 0.0455 |
Brugia malayi | jmjC domain containing protein | 0.0043 | 0.0283 | 0.0477 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0502 | 0.5228 | 1 |
Loa Loa (eye worm) | hexokinase | 0.003 | 0.0144 | 0.0257 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0136 | 0.0242 |
Echinococcus granulosus | heat shock protein heat shock protein 90 alpha | 0.0047 | 0.0334 | 0.0572 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0108 | 0.0982 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0023 | 0.0073 | 0.0349 |
Loa Loa (eye worm) | hexokinase | 0.0096 | 0.086 | 0.1629 |
Entamoeba histolytica | protein kinase, putative | 0.0108 | 0.0982 | 1 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0047 | 0.0334 | 0.0572 |
Schistosoma mansoni | hexokinase | 0.0096 | 0.086 | 0.1586 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0042 | 0.0271 | 0.0455 |
Echinococcus multilocularis | musashi | 0.0063 | 0.0497 | 0.0462 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0057 | 0.0439 | 0.2067 |
Trichomonas vaginalis | heat shock protein, putative | 0.0047 | 0.0334 | 0.0572 |
Brugia malayi | RNA binding protein | 0.0076 | 0.0648 | 0.118 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.0166 | 0.025 |
Plasmodium vivax | heat shock protein, putative | 0.021 | 0.2084 | 1 |
Echinococcus granulosus | peregrin | 0.0035 | 0.0203 | 0.032 |
Trypanosoma brucei | heat shock protein 84, putative | 0.0037 | 0.022 | 0.0352 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0032 | 0.0166 | 0.013 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0035 | 0.0203 | 0.0167 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0023 | 0.0073 | 0.0349 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0057 | 0.0439 | 0.0775 |
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 0.0648 | 0.1177 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0055 | 0.0419 | 0.0783 |
Trichomonas vaginalis | esterase, putative | 0.0042 | 0.0271 | 0.0452 |
Onchocerca volvulus | 0.0063 | 0.0497 | 0.1471 | |
Toxoplasma gondii | heat shock protein 75, putative | 0.0037 | 0.022 | 0.0352 |
Trichomonas vaginalis | set domain proteins, putative | 0.0253 | 0.2545 | 0.4832 |
Mycobacterium leprae | conserved hypothetical protein | 0.0042 | 0.0271 | 0.151 |
Onchocerca volvulus | 0.0042 | 0.0271 | 0.0687 | |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0166 | 0.1617 | 0.3044 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0055 | 0.0419 | 0.0739 |
Echinococcus granulosus | tar DNA binding protein | 0.0076 | 0.0648 | 0.1177 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0055 | 0.0419 | 0.0736 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0502 | 0.5228 | 1 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0055 | 0.042 | 0.0738 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.042 | 0.0738 |
Leishmania major | heat shock protein, putative | 0.0037 | 0.022 | 0.0352 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0152 | 0.0271 |
Echinococcus multilocularis | hexokinase | 0.0096 | 0.086 | 0.0826 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.003 | 0.0149 | 0.0112 |
Brugia malayi | Pre-SET motif family protein | 0.0032 | 0.0166 | 0.0253 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0042 | 0.0271 | 0.1011 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.013 | 0.1227 | 0.4571 |
Trypanosoma brucei | CMGC/DYRK protein kinase, putative | 0.0108 | 0.0982 | 0.1822 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0042 | 0.0271 | 0.0452 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0166 | 0.1617 | 0.3044 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0023 | 0.0073 | 0.0349 |
Plasmodium vivax | hexokinase, putative | 0.0096 | 0.086 | 0.4099 |
Plasmodium vivax | hypothetical protein, conserved | 0.0042 | 0.0271 | 0.1259 |
Brugia malayi | Protein kinase domain containing protein | 0.0108 | 0.0982 | 0.1824 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0032 | 0.0166 | 0.025 |
Entamoeba histolytica | protein kinase, putative | 0.0108 | 0.0982 | 1 |
Trichomonas vaginalis | heat shock protein, putative | 0.004 | 0.0256 | 0.0423 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0055 | 0.042 | 0.3811 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0023 | 0.0073 | 0.0349 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0043 | 0.0283 | 0.0474 |
Trichomonas vaginalis | heat shock protein, putative | 0.0032 | 0.017 | 0.0257 |
Leishmania major | serine/threonine-protein kinase, putative,protein kinase, putative | 0.0108 | 0.0982 | 0.1822 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0502 | 0.5228 | 0.5211 |
Leishmania major | trypanothione reductase | 0.0057 | 0.0439 | 0.0775 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0042 | 0.0271 | 0.0452 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0035 | 0.0203 | 0.032 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0502 | 0.5228 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0271 | 0.05 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0049 | 0.0351 | 0.0316 |
Mycobacterium tuberculosis | Conserved protein | 0.0042 | 0.0271 | 0.1011 |
Loa Loa (eye worm) | hexokinase | 0.0096 | 0.086 | 0.1629 |
Brugia malayi | Hexokinase family protein | 0.0096 | 0.086 | 0.1588 |
Trypanosoma cruzi | hexokinase, putative | 0.0096 | 0.086 | 0.1586 |
Mycobacterium tuberculosis | Conserved protein | 0.0042 | 0.0271 | 0.1011 |
Leishmania major | hexokinase, putative | 0.0096 | 0.086 | 0.1586 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.003 | 0.0152 | 0.0682 |
Trypanosoma brucei | hexokinase, putative | 0.0096 | 0.086 | 0.1586 |
Brugia malayi | beta-lactamase | 0.0042 | 0.0271 | 0.0455 |
Brugia malayi | Hexokinase family protein | 0.006 | 0.0474 | 0.0844 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0145 | 0.1384 | 0.5155 |
Mycobacterium ulcerans | beta-lactamase | 0.0042 | 0.0271 | 0.1443 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0057 | 0.0439 | 0.1635 |
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 0.0648 | 0.1177 |
Trypanosoma brucei | protein kinase, putative | 0.0502 | 0.5228 | 1 |
Onchocerca volvulus | Hexokinase homolog | 0.006 | 0.0474 | 0.1389 |
Mycobacterium tuberculosis | Conserved protein | 0.0042 | 0.0271 | 0.1011 |
Trypanosoma brucei | heat shock protein, putative | 0.0055 | 0.042 | 0.0738 |
Schistosoma mansoni | hypothetical protein | 0.0205 | 0.2029 | 0.3837 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0042 | 0.0271 | 0.1443 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0017 | 0.001 | 0.0038 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0042 | 0.0271 | 0.1011 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.042 | 0.0738 |
Mycobacterium ulcerans | heat shock protein 90 | 0.0052 | 0.0383 | 0.2061 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0497 | 0.0934 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0042 | 0.0271 | 0.1011 |
Brugia malayi | hypothetical protein | 0.0164 | 0.1593 | 0.3 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.042 | 0.0738 |
Echinococcus granulosus | hexokinase type 2 | 0.0096 | 0.086 | 0.1586 |
Plasmodium falciparum | phd finger protein, putative | 0.0035 | 0.0203 | 0.0929 |
Trichomonas vaginalis | heat shock protein, putative | 0.0052 | 0.0383 | 0.0667 |
Brugia malayi | PHD-finger family protein | 0.0035 | 0.0203 | 0.0323 |
Schistosoma mansoni | intermediate filament proteins | 0.0063 | 0.0497 | 0.0887 |
Echinococcus granulosus | lamin | 0.0063 | 0.0497 | 0.0887 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0042 | 0.0271 | 0.1443 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0073 | 0.0071 |
Toxoplasma gondii | hypothetical protein | 0.0057 | 0.0435 | 0.0767 |
Trypanosoma brucei | hexokinase | 0.0096 | 0.086 | 0.1586 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI50 (functional) | -8 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -8 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -8 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the P388 Leukemia cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -7.603 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -7.325 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -7.033 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -7 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -6.979 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -6.956 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -6.838 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -6.775 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -5.991 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.