Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | epsilon tubulin, putative | 0.0812 | 0.4723 | 0.4723 |
Leishmania major | alpha tubulin | 0.102 | 0.5949 | 0.5949 |
Loa Loa (eye worm) | Na,K-ATPase alpha subunit | 0.0014 | 0.0016 | 0.0004 |
Trichomonas vaginalis | tubulin alpha-1 chain, putative | 0.102 | 0.5949 | 0.5949 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0016 | 0.0004 |
Giardia lamblia | Epsilon tubulin | 0.0353 | 0.2014 | 0.2014 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0013 | 0.0012 | 0.0012 |
Loa Loa (eye worm) | tubulin alpha 2 | 0.0208 | 0.1161 | 0.1151 |
Onchocerca volvulus | 0.0014 | 0.0016 | 0.0017 | |
Entamoeba histolytica | tubulin gamma chain | 0.0812 | 0.4723 | 0.4715 |
Echinococcus multilocularis | tubulin subunit TubB | 0.102 | 0.5949 | 0.5949 |
Entamoeba histolytica | tubulin alpha-1 chain | 0.102 | 0.5949 | 0.5943 |
Trypanosoma cruzi | plasma membrane Ca2+ ATPase | 0.0014 | 0.0016 | 0.0016 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.0013 | 0.0012 | 0.0012 |
Loa Loa (eye worm) | tubulin alpha chain | 0.102 | 0.5949 | 0.5944 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.0131 | 0.0131 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0.0092 | 0.0092 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0012 | 0.0006 | 0.0006 |
Echinococcus granulosus | tubulin alpha 3 chain | 0.102 | 0.5949 | 0.5949 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0015 | 0.0026 | 0.0026 |
Trichomonas vaginalis | tubulin alpha chain, putative | 0.0812 | 0.4723 | 0.4723 |
Loa Loa (eye worm) | hypothetical protein | 0.102 | 0.5949 | 0.5944 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0284 | 0.161 | 0.161 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.046 | 0.2644 | 0.2644 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta2-like) | 0.0013 | 0.0012 | 0.0012 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0092 | 0.008 |
Leishmania major | alpha tubulin | 0.102 | 0.5949 | 0.5949 |
Leishmania major | vacuolar-type Ca2 -ATPase, putative | 0.0014 | 0.0016 | 0.0016 |
Plasmodium falciparum | tubulin epsilon chain, putative | 0.0812 | 0.4723 | 0.4723 |
Plasmodium falciparum | tubulin delta chain, putative | 0.0353 | 0.2014 | 0.2014 |
Echinococcus multilocularis | nervana 2 | 0.0021 | 0.0057 | 0.0057 |
Leishmania major | alpha tubulin | 0.102 | 0.5949 | 0.5949 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.102 | 0.5949 | 0.5949 |
Trichomonas vaginalis | tubulin, putative | 0.0353 | 0.2014 | 0.2014 |
Schistosoma mansoni | tubulin subunit beta | 0.0353 | 0.2014 | 0.2014 |
Brugia malayi | alpha-tubulin | 0.102 | 0.5949 | 0.5949 |
Trypanosoma cruzi | Calcium ATPase SERCA-like | 0.0014 | 0.0016 | 0.0016 |
Entamoeba histolytica | tubulin alpha chain, putative | 0.102 | 0.5949 | 0.5943 |
Schistosoma mansoni | alpha tubulin | 0.102 | 0.5949 | 0.5949 |
Trichomonas vaginalis | plasma membrane calcium-transporting ATPase, putative | 0.0014 | 0.0016 | 0.0016 |
Brugia malayi | Cation transporter family protein | 0.0013 | 0.0012 | 0.0012 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit type | 0.0013 | 0.0012 | 0.0012 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0026 | 0.0026 |
Loa Loa (eye worm) | alpha-tubulin | 0.102 | 0.5949 | 0.5944 |
Brugia malayi | Tubulin alpha chain | 0.102 | 0.5949 | 0.5949 |
Echinococcus granulosus | tubulin alpha | 0.0812 | 0.4723 | 0.4723 |
Echinococcus granulosus | peroxisome assembly protein 26 | 0.102 | 0.5949 | 0.5949 |
Echinococcus multilocularis | GPCR, family 2 | 0.0015 | 0.0026 | 0.0026 |
Toxoplasma gondii | tubulin/FtsZ family, GTPase domain-containing protein | 0.0812 | 0.4723 | 0.4723 |
Loa Loa (eye worm) | hypothetical protein | 0.0494 | 0.2845 | 0.2836 |
Leishmania major | alpha tubulin | 0.102 | 0.5949 | 0.5949 |
Toxoplasma gondii | alpha-tubulin I, putative | 0.102 | 0.5949 | 0.5949 |
Schistosoma mansoni | alpha tubulin | 0.102 | 0.5949 | 0.5949 |
Echinococcus multilocularis | neuronal acetylcholine receptor subunit alpha 4 | 0.0013 | 0.0012 | 0.0012 |
Echinococcus multilocularis | tubulin alpha 1C chain | 0.102 | 0.5949 | 0.5949 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit alpha 8 | 0.0013 | 0.0012 | 0.0012 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0013 | 0.0012 | 0.0012 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.0021 | 0.0057 | 0.0057 |
Brugia malayi | excitatory GABA receptor EXP-1A | 0.0013 | 0.0012 | 0.0012 |
Loa Loa (eye worm) | tubulin alpha-2 chain | 0.102 | 0.5949 | 0.5944 |
Leishmania major | alpha tubulin | 0.102 | 0.5949 | 0.5949 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0013 | 0.0012 | 0.0012 |
Trichomonas vaginalis | tubulin alpha-1 chain, putative | 0.0668 | 0.387 | 0.387 |
Trichomonas vaginalis | tubulin epsilon chain, putative | 0.102 | 0.5949 | 0.5949 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0013 | 0.0012 | 0.0012 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0012 | 0.0006 | 0.0006 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0013 | 0.0012 | 0.0012 |
Schistosoma mansoni | nAChR subunit | 0.0013 | 0.0012 | 0.0012 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.0021 | 0.0057 | 0.0057 |
Leishmania major | alpha tubulin | 0.102 | 0.5949 | 0.5949 |
Brugia malayi | Tubulin beta chain | 0.0353 | 0.2014 | 0.2014 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.102 | 0.5949 | 0.5949 |
Plasmodium vivax | delta tubulin, putative | 0.0353 | 0.2014 | 0.2001 |
Schistosoma mansoni | sodium / potassium ATPase beta chain | 0.0021 | 0.0057 | 0.0057 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0057 | 0.0045 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0016 | 0.0004 |
Echinococcus multilocularis | Tubulin alpha 1 chain | 0.102 | 0.5949 | 0.5949 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.0013 | 0.0012 | 0.0012 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0027 | 0.0092 | 0.0092 |
Trypanosoma brucei | alpha tubulin | 0.102 | 0.5949 | 0.5949 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.0013 | 0.0012 | 0.0012 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0013 | 0.0012 | 0.0012 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0026 | 0.0026 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0013 | 0.0012 | 0.0012 |
Schistosoma mansoni | tubulin subunit alpha | 0.102 | 0.5949 | 0.5949 |
Trichomonas vaginalis | tubulin epsilon chain, putative | 0.102 | 0.5949 | 0.5949 |
Loa Loa (eye worm) | alpha-tubulin isotype 2 | 0.0668 | 0.387 | 0.3863 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0026 | 0.0026 |
Echinococcus multilocularis | tubulin alpha chain | 0.102 | 0.5949 | 0.5949 |
Echinococcus granulosus | tubulin alpha 3 chain | 0.102 | 0.5949 | 0.5949 |
Leishmania major | alpha tubulin | 0.102 | 0.5949 | 0.5949 |
Trypanosoma brucei | epsilon tubulin | 0.0812 | 0.4723 | 0.4723 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.0021 | 0.0057 | 0.0057 |
Echinococcus multilocularis | tubulin alpha chain | 0.102 | 0.5949 | 0.5949 |
Schistosoma mansoni | ATPase | 0.0014 | 0.0016 | 0.0016 |
Loa Loa (eye worm) | tubulin beta chain | 0.0353 | 0.2014 | 0.2005 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0026 | 0.0026 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0284 | 0.161 | 0.1597 |
Loa Loa (eye worm) | tubulin gamma chain | 0.0812 | 0.4723 | 0.4717 |
Schistosoma mansoni | ATPase | 0.0014 | 0.0016 | 0.0016 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0353 | 0.2014 | 0.2014 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0013 | 0.0012 | 0.0012 |
Trypanosoma cruzi | tubulin delta chain | 0.0353 | 0.2014 | 0.2014 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0026 | 0.0026 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0013 | 0.0012 | 0.0012 |
Brugia malayi | tubulin alpha-2 chain | 0.102 | 0.5949 | 0.5949 |
Trichomonas vaginalis | tubulin alpha chain, putative | 0.046 | 0.2644 | 0.2644 |
Toxoplasma gondii | tubulin/FtsZ family, GTPase domain-containing protein | 0.0353 | 0.2014 | 0.2014 |
Trichomonas vaginalis | plasma membrane calcium-transporting ATPase, putative | 0.0014 | 0.0016 | 0.0016 |
Trypanosoma brucei | alpha tubulin | 0.102 | 0.5949 | 0.5949 |
Echinococcus multilocularis | nicotinic acetylcholine receptor a11 subunit | 0.0013 | 0.0012 | 0.0012 |
Schistosoma mansoni | transmemberane protein | 0.0021 | 0.0057 | 0.0057 |
Echinococcus granulosus | sarco:endoplasmic reticulum calcium ATPase | 0.0014 | 0.0016 | 0.0016 |
Giardia lamblia | Alpha-tubulin | 0.102 | 0.5949 | 0.5949 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0131 | 0.0119 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0013 | 0.0012 | 0.0012 |
Toxoplasma gondii | tubulin/FtsZ family, GTPase domain-containing protein | 0.0353 | 0.2014 | 0.2014 |
Plasmodium falciparum | tubulin gamma chain | 0.0812 | 0.4723 | 0.4723 |
Echinococcus granulosus | nAChR subunit | 0.0013 | 0.0012 | 0.0012 |
Echinococcus multilocularis | tubulin epsilon chain | 0.0812 | 0.4723 | 0.4723 |
Echinococcus granulosus | nicotinic acetylcholine receptor beta 1 subunit | 0.0013 | 0.0012 | 0.0012 |
Brugia malayi | Tubulin gamma chain | 0.0812 | 0.4723 | 0.4723 |
Echinococcus granulosus | tubulin epsilon chain | 0.0812 | 0.4723 | 0.4723 |
Trichomonas vaginalis | tubulin gamma chain, putative | 0.0812 | 0.4723 | 0.4723 |
Echinococcus granulosus | calcium transporting ATPase type 2C member | 0.0014 | 0.0016 | 0.0016 |
Schistosoma mansoni | tubulin subunit delta | 0.0353 | 0.2014 | 0.2014 |
Echinococcus granulosus | alpha tubulin | 0.102 | 0.5949 | 0.5949 |
Trichomonas vaginalis | plasma membrane calcium-transporting ATPase, putative | 0.0014 | 0.0016 | 0.0016 |
Trypanosoma brucei | vacuolar-type Ca2+-ATPase 1 | 0.0014 | 0.0016 | 0.0016 |
Trichomonas vaginalis | cation-transporting ATPase fungi, putative | 0.0014 | 0.0016 | 0.0016 |
Schistosoma mansoni | nAChR subunit | 0.0013 | 0.0012 | 0.0012 |
Trypanosoma cruzi | alpha tubulin, putative | 0.102 | 0.5949 | 0.5949 |
Giardia lamblia | Plasma membrane calcium-transporting ATPase 2 | 0.0014 | 0.0016 | 0.0016 |
Trypanosoma brucei | tubulin delta chain | 0.0353 | 0.2014 | 0.2014 |
Echinococcus granulosus | tubulin alpha chain | 0.102 | 0.5949 | 0.5949 |
Trypanosoma brucei | beta tubulin | 0.0812 | 0.4723 | 0.4723 |
Toxoplasma gondii | P-type ATPase4, putative | 0.0014 | 0.0016 | 0.0016 |
Echinococcus granulosus | tubulin alpha 1C chain | 0.102 | 0.5949 | 0.5949 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0284 | 0.161 | 0.161 |
Echinococcus multilocularis | tubulin alpha 3 chain | 0.102 | 0.5949 | 0.5949 |
Echinococcus multilocularis | nicotinic acetylcholine receptor beta 1 subunit | 0.0013 | 0.0012 | 0.0012 |
Echinococcus granulosus | Tubulin alpha 1 chain | 0.102 | 0.5949 | 0.5949 |
Echinococcus multilocularis | nicotinic acetylcholine receptor alpha subunit | 0.0013 | 0.0012 | 0.0012 |
Brugia malayi | acetylcholine receptor, alpha-type subunit unc-38 precursor | 0.0013 | 0.0012 | 0.0012 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0284 | 0.161 | 0.161 |
Schistosoma mansoni | alzheimer's disease beta-amyloid related | 0.0228 | 0.1282 | 0.1282 |
Echinococcus granulosus | tubulin alpha chain | 0.102 | 0.5949 | 0.5949 |
Loa Loa (eye worm) | hypothetical protein | 0.0132 | 0.0716 | 0.0705 |
Brugia malayi | Tubulin beta chain | 0.046 | 0.2644 | 0.2644 |
Echinococcus multilocularis | nervana 2 | 0.0021 | 0.0057 | 0.0057 |
Echinococcus granulosus | tubulin alpha chain | 0.102 | 0.5949 | 0.5949 |
Echinococcus multilocularis | tubulin alpha chain | 0.102 | 0.5949 | 0.5949 |
Leishmania major | alpha tubulin | 0.102 | 0.5949 | 0.5949 |
Trichomonas vaginalis | cation-transporting ATPase, putative | 0.0014 | 0.0016 | 0.0016 |
Trichomonas vaginalis | tubulin gamma chain, putative | 0.0812 | 0.4723 | 0.4723 |
Trichomonas vaginalis | tubulin alpha chain, putative | 0.046 | 0.2644 | 0.2644 |
Mycobacterium leprae | cell division protein FtsZ | 0.0353 | 0.2014 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0013 | 0.0012 | 0.0012 |
Echinococcus granulosus | nicotinic acetylcholine receptor alpha subunit | 0.0013 | 0.0012 | 0.0012 |
Echinococcus granulosus | neuronal acetylcholine receptor subunit alpha 4 | 0.0013 | 0.0012 | 0.0012 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0013 | 0.0012 | 0.0012 |
Schistosoma mansoni | tubulin subunit alpha | 0.0353 | 0.2014 | 0.2014 |
Plasmodium vivax | tubulin alpha chain, putative | 0.102 | 0.5949 | 0.5943 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0013 | 0.0012 | 0.0012 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0221 | 0.021 |
Trypanosoma cruzi | plasma membrane Ca2+ ATPase | 0.0014 | 0.0016 | 0.0016 |
Mycobacterium tuberculosis | Cell division protein FtsZ | 0.0353 | 0.2014 | 1 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0013 | 0.0012 | 0.0012 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0353 | 0.2014 | 0.2014 |
Echinococcus granulosus | acetylcholine receptor subunit beta 1 | 0.0013 | 0.0012 | 0.0012 |
Brugia malayi | acetylcholine receptor protein, alpha-like chain, putative | 0.0013 | 0.0012 | 0.0012 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.102 | 0.5949 | 0.5949 |
Brugia malayi | Amyloid A4 extracellular domain containing protein | 0.0626 | 0.3628 | 0.3628 |
Echinococcus multilocularis | tubulin alpha 3 chain | 0.102 | 0.5949 | 0.5949 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0015 | 0.0026 | 0.0014 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0013 | 0.0012 | 0.0012 |
Brugia malayi | Na,K-ATPase alpha subunit | 0.0014 | 0.0016 | 0.0016 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.0021 | 0.0057 | 0.0057 |
Leishmania major | vacuolar-type Ca2 -ATPase, putative | 0.0014 | 0.0016 | 0.0016 |
Brugia malayi | Cation transporter family protein | 0.0013 | 0.0012 | 0.0012 |
Schistosoma mansoni | tubulin subunit alpha | 0.102 | 0.5949 | 0.5949 |
Schistosoma mansoni | hypothetical protein | 0.0012 | 0.0006 | 0.0006 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0284 | 0.161 | 0.161 |
Trypanosoma cruzi | tubulin delta chain | 0.0353 | 0.2014 | 0.2014 |
Loa Loa (eye worm) | alpha-tubulin | 0.102 | 0.5949 | 0.5944 |
Echinococcus granulosus | tubulin alpha chain | 0.102 | 0.5949 | 0.5949 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0057 | 0.0045 |
Trichomonas vaginalis | cation-transporting ATPase, putative | 0.0014 | 0.0016 | 0.0016 |
Giardia lamblia | Gamma tubulin | 0.0812 | 0.4723 | 0.4723 |
Toxoplasma gondii | sarco/endoplasmic reticulum Ca2+-ATPase | 0.0014 | 0.0016 | 0.0016 |
Trypanosoma brucei | epsilon tubulin | 0.0812 | 0.4723 | 0.4723 |
Onchocerca volvulus | 0.046 | 0.2644 | 1 | |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0027 | 0.0092 | 0.0092 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0116 | 0.0619 | 0.0609 |
Echinococcus granulosus | nervana 2 | 0.0021 | 0.0057 | 0.0057 |
Leishmania major | delta tubulin, putative | 0.0353 | 0.2014 | 0.2014 |
Brugia malayi | gamma-aminobutyric-acid receptor beta subunit precursor | 0.0013 | 0.0012 | 0.0012 |
Brugia malayi | acetylcholine receptor alpha subunit precursor, putative | 0.0013 | 0.0012 | 0.0012 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0027 | 0.0092 | 0.0076 |
Echinococcus granulosus | nicotinic acetylcholine receptor a11 subunit | 0.0013 | 0.0012 | 0.0012 |
Onchocerca volvulus | 0.0021 | 0.0057 | 0.0172 | |
Brugia malayi | hypothetical protein | 0.0027 | 0.0092 | 0.0092 |
Echinococcus multilocularis | sarco:endoplasmic reticulum calcium ATPase | 0.0014 | 0.0016 | 0.0016 |
Loa Loa (eye worm) | tubulin alpha-3 chain | 0.0561 | 0.324 | 0.3232 |
Echinococcus multilocularis | calcium transporting ATPase type 2C member | 0.0014 | 0.0016 | 0.0016 |
Loa Loa (eye worm) | hypothetical protein | 0.0561 | 0.324 | 0.3232 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0027 | 0.0092 | 0.0092 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0013 | 0.0012 | 0.0012 |
Toxoplasma gondii | calcium-translocating P-type ATPase, PMCA-type protein | 0.0014 | 0.0016 | 0.0016 |
Giardia lamblia | Alpha-tubulin | 0.102 | 0.5949 | 0.5949 |
Trypanosoma brucei | zeta tubulin | 0.0353 | 0.2014 | 0.2014 |
Echinococcus granulosus | plasma membrane calcium transporting ATPase 2 | 0.0014 | 0.0016 | 0.0016 |
Trichomonas vaginalis | tubulin epsilon chain, putative | 0.0353 | 0.2014 | 0.2014 |
Leishmania major | gamma-tubulin | 0.0812 | 0.4723 | 0.4723 |
Plasmodium falciparum | alpha tubulin 1 | 0.102 | 0.5949 | 0.5949 |
Trichomonas vaginalis | tubulin gamma chain, putative | 0.0353 | 0.2014 | 0.2014 |
Echinococcus multilocularis | tubulin alpha chain | 0.102 | 0.5949 | 0.5949 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.102 | 0.5949 | 0.5949 |
Echinococcus granulosus | sodium:potassium transporting ATPase subunit | 0.0021 | 0.0057 | 0.0057 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0026 | 0.0026 |
Trichomonas vaginalis | tubulin beta-1 chain, putative | 0.0353 | 0.2014 | 0.2014 |
Loa Loa (eye worm) | tubulin alpha 2 | 0.0668 | 0.387 | 0.3863 |
Trichomonas vaginalis | tubulin alpha-1 chain, putative | 0.0561 | 0.324 | 0.324 |
Schistosoma mansoni | Na+/K+ transporting ATPase subunit alpha | 0.0014 | 0.0016 | 0.0016 |
Echinococcus granulosus | Tubulin alpha 1 chain | 0.102 | 0.5949 | 0.5949 |
Trichomonas vaginalis | plasma membrane calcium-transporting ATPase, putative | 0.0014 | 0.0016 | 0.0016 |
Trypanosoma brucei | alpha tubulin | 0.102 | 0.5949 | 0.5949 |
Leishmania major | calcium-translocating P-type ATPase | 0.0014 | 0.0016 | 0.0016 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0013 | 0.0012 | 0.0012 |
Trypanosoma cruzi | zeta tubulin, putative | 0.0353 | 0.2014 | 0.2014 |
Leishmania major | alpha tubulin | 0.102 | 0.5949 | 0.5949 |
Plasmodium falciparum | non-SERCA-type Ca2+ -transporting P-ATPase | 0.0014 | 0.0016 | 0.0016 |
Echinococcus multilocularis | Tetracycline resistance leader peptide, TetL | 0.0014 | 0.0016 | 0.0016 |
Schistosoma mansoni | sodium/potassium-dependent atpase beta subunit | 0.0021 | 0.0057 | 0.0057 |
Brugia malayi | Cell division protein ftsZ | 0.0353 | 0.2014 | 0.2014 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0048 | 0.0221 | 0.0221 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.102 | 0.5949 | 0.5949 |
Trichomonas vaginalis | tubulin alpha chain, putative | 0.046 | 0.2644 | 0.2644 |
Plasmodium vivax | tubulin epsilon chain, putative | 0.0812 | 0.4723 | 0.4715 |
Mycobacterium ulcerans | cell division protein FtsZ | 0.0353 | 0.2014 | 1 |
Trypanosoma cruzi | zeta tubulin, putative | 0.0353 | 0.2014 | 0.2014 |
Echinococcus multilocularis | sodium:potassium transporting ATPase subunit | 0.0021 | 0.0057 | 0.0057 |
Leishmania major | zeta tubulin, putative | 0.0353 | 0.2014 | 0.2014 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0026 | 0.0026 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0284 | 0.161 | 0.161 |
Brugia malayi | Tubulin alpha-2 chain | 0.102 | 0.5949 | 0.5949 |
Loa Loa (eye worm) | tubulin alpha chain | 0.102 | 0.5949 | 0.5944 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0284 | 0.161 | 0.161 |
Schistosoma mansoni | alpha tubulin | 0.102 | 0.5949 | 0.5949 |
Leishmania major | alpha tubulin | 0.102 | 0.5949 | 0.5949 |
Leishmania major | alpha tubulin | 0.102 | 0.5949 | 0.5949 |
Loa Loa (eye worm) | hypothetical protein | 0.0265 | 0.1498 | 0.1489 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0.0092 | 0.0092 |
Trypanosoma brucei | vacuolar-type Ca2+-ATPase, putative | 0.0014 | 0.0016 | 0.0016 |
Leishmania major | epsilon tubulin, putative | 0.0812 | 0.4723 | 0.4723 |
Echinococcus multilocularis | nAChR subunit | 0.0013 | 0.0012 | 0.0012 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0013 | 0.0012 | 0.0012 |
Echinococcus multilocularis | Tubulin alpha 1 chain | 0.102 | 0.5949 | 0.5949 |
Trypanosoma brucei | epsilon tubulin | 0.0812 | 0.4723 | 0.4723 |
Schistosoma mansoni | tubulin subunit epsilon | 0.0812 | 0.4723 | 0.4723 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit alpha 8 | 0.0013 | 0.0012 | 0.0012 |
Plasmodium vivax | tubulin alpha chain, putative | 0.102 | 0.5949 | 0.5943 |
Brugia malayi | nicotinic acetylcholine receptor beta-1 chain precursor | 0.0013 | 0.0012 | 0.0012 |
Schistosoma mansoni | nAChR subunit | 0.0013 | 0.0012 | 0.0012 |
Onchocerca volvulus | 0.0021 | 0.0057 | 0.0172 | |
Brugia malayi | Tubulin alpha chain | 0.0353 | 0.2014 | 0.2014 |
Loa Loa (eye worm) | hypothetical protein | 0.0668 | 0.387 | 0.3863 |
Echinococcus granulosus | nervana 2 | 0.0021 | 0.0057 | 0.0057 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0013 | 0.0012 | 0.0012 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0116 | 0.0619 | 0.0609 |
Leishmania major | hypothetical protein, conserved | 0.0027 | 0.0092 | 0.0092 |
Brugia malayi | MH2 domain containing protein | 0.0116 | 0.0619 | 0.0619 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0284 | 0.161 | 0.1597 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0284 | 0.161 | 0.161 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0026 | 0.0014 |
Echinococcus multilocularis | tubulin gamma 1 chain | 0.0812 | 0.4723 | 0.4723 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0013 | 0.0012 | 0.0012 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.0021 | 0.0057 | 0.0057 |
Echinococcus granulosus | tubulin gamma 1 chain | 0.0812 | 0.4723 | 0.4723 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.0021 | 0.0057 | 0.0057 |
Echinococcus granulosus | tubulin delta chain | 0.0353 | 0.2014 | 0.2014 |
Trypanosoma brucei | tubulin gamma chain | 0.0812 | 0.4723 | 0.4723 |
Trichomonas vaginalis | tubulin alpha-1 chain, putative | 0.046 | 0.2644 | 0.2644 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0048 | 0.0221 | 0.0221 |
Leishmania major | alpha tubulin | 0.102 | 0.5949 | 0.5949 |
Echinococcus granulosus | Tubulin alpha 1 chain | 0.102 | 0.5949 | 0.5949 |
Echinococcus granulosus | GPCR family 2 | 0.0015 | 0.0026 | 0.0026 |
Echinococcus multilocularis | Tubulin alpha 1 chain | 0.102 | 0.5949 | 0.5949 |
Trypanosoma brucei | alpha tubulin, putative | 0.046 | 0.2644 | 0.2644 |
Giardia lamblia | Delta tubulin | 0.0353 | 0.2014 | 0.2014 |
Brugia malayi | tubulin alpha chain - mouse | 0.102 | 0.5949 | 0.5949 |
Echinococcus granulosus | tubulin subunit TubB | 0.102 | 0.5949 | 0.5949 |
Echinococcus multilocularis | hypothetical protein | 0.102 | 0.5949 | 0.5949 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0284 | 0.161 | 0.161 |
Schistosoma mansoni | nAChR subunit | 0.0013 | 0.0012 | 0.0012 |
Echinococcus multilocularis | tubulin alpha chain | 0.102 | 0.5949 | 0.5949 |
Trypanosoma cruzi | epsilon tubulin, putative | 0.0812 | 0.4723 | 0.4723 |
Echinococcus granulosus | nervana 2 | 0.0021 | 0.0057 | 0.0057 |
Schistosoma mansoni | nAChR subunit | 0.0013 | 0.0012 | 0.0012 |
Trichomonas vaginalis | plasma membrane calcium-transporting ATPase, putative | 0.0014 | 0.0016 | 0.0016 |
Echinococcus multilocularis | acetylcholine receptor subunit beta 1 | 0.0013 | 0.0012 | 0.0012 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0013 | 0.0012 | 0.0012 |
Trichomonas vaginalis | tubulin, putative | 0.046 | 0.2644 | 0.2644 |
Brugia malayi | Tubulin alpha-2 chain | 0.102 | 0.5949 | 0.5949 |
Echinococcus multilocularis | nervana 2 | 0.0021 | 0.0057 | 0.0057 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0284 | 0.161 | 0.161 |
Echinococcus multilocularis | tubulin alpha | 0.0812 | 0.4723 | 0.4723 |
Trypanosoma cruzi | tubulin gamma chain | 0.0812 | 0.4723 | 0.4723 |
Trypanosoma brucei | alpha tubulin | 0.102 | 0.5949 | 0.5949 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0139 | 0.0754 | 0.369 |
Brugia malayi | Cation transporter family protein | 0.0013 | 0.0012 | 0.0012 |
Brugia malayi | nicotinic acetylcholine receptor alpha subunit, putative | 0.0013 | 0.0012 | 0.0012 |
Schistosoma mansoni | sodium/potassium-dependent atpase beta subunit | 0.0021 | 0.0057 | 0.0057 |
Trichomonas vaginalis | cation-transporting ATPase, putative | 0.0014 | 0.0016 | 0.0016 |
Echinococcus granulosus | nervana 2 | 0.0021 | 0.0057 | 0.0057 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0013 | 0.0012 | 0.0012 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0013 | 0.0012 | 0.0012 |
Trypanosoma brucei | zeta tubulin, putative | 0.0353 | 0.2014 | 0.2014 |
Schistosoma mansoni | nAChR subunit | 0.0013 | 0.0012 | 0.0012 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.102 | 0.5949 | 0.5949 |
Wolbachia endosymbiont of Brugia malayi | cell division protein FtsZ | 0.0353 | 0.2014 | 0.5 |
Trypanosoma brucei | vacuolar-type Ca2+-ATPase 2 | 0.0014 | 0.0016 | 0.0016 |
Echinococcus granulosus | tubulin alpha chain | 0.102 | 0.5949 | 0.5949 |
Schistosoma mansoni | sodium/potassium-dependent atpase beta subunit | 0.0021 | 0.0057 | 0.0057 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0015 | 0.0026 | 0.0026 |
Treponema pallidum | cell division protein FtsZ | 0.0353 | 0.2014 | 1 |
Schistosoma mansoni | tubulin subunit alpha | 0.102 | 0.5949 | 0.5949 |
Echinococcus granulosus | tubulin alpha 1C chain | 0.102 | 0.5949 | 0.5949 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0048 | 0.0221 | 0.021 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0026 | 0.0026 |
Schistosoma mansoni | nAChR subunit | 0.0013 | 0.0012 | 0.0012 |
Echinococcus multilocularis | nervana 2 | 0.0021 | 0.0057 | 0.0057 |
Schistosoma mansoni | tubulin subunit gamma | 0.0812 | 0.4723 | 0.4723 |
Trichomonas vaginalis | tubulin, putative | 0.046 | 0.2644 | 0.2644 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0131 | 0.0131 |
Loa Loa (eye worm) | tubulin alpha 2 | 0.0668 | 0.387 | 0.3863 |
Echinococcus multilocularis | tubulin delta chain | 0.0353 | 0.2014 | 0.2014 |
Echinococcus multilocularis | tubulin alpha 1C chain | 0.102 | 0.5949 | 0.5949 |
Plasmodium falciparum | alpha tubulin 2 | 0.102 | 0.5949 | 0.5949 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.0013 | 0.0012 | 0.0012 |
Echinococcus multilocularis | peroxisome assembly protein 26 | 0.102 | 0.5949 | 0.5949 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0036 | 0.0036 |
Toxoplasma gondii | alpha tubulin TUBA1 | 0.102 | 0.5949 | 0.5949 |
Plasmodium vivax | tubulin gamma chain, putative | 0.0812 | 0.4723 | 0.4715 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0027 | 0.0092 | 0.0092 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (binding) | = 71 % | Inhibition of recombinant SphK2 expressed in baculovirus infected Sf9 cells using D-erythro-sphingosine as substrate and [32gammaP]ATP assessed as residual activity at 10 uM by scintillation counting | ChEMBL. | 22321213 |
Activity (binding) | = 89 % | Inhibition of recombinant SphK1 expressed in baculovirus infected Sf9 cells using D-erythro-sphingosine as substrate and [32gammaP]ATP assessed as residual activity at 10 uM by scintillation counting | ChEMBL. | 22321213 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.