Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Treponema pallidum | cyclic nucleotide binding protein | 0.0037 | 0.0346 | 0.1081 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0088 | 0.1946 | 1 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.0037 | 0.0346 | 0.0346 |
Plasmodium vivax | CAMP-dependent protein kinase regulatory subunit, putative | 0.0037 | 0.0346 | 0.1448 |
Echinococcus granulosus | cAMP dependent protein kinase type II regulatory | 0.0037 | 0.0346 | 0.0346 |
Echinococcus granulosus | cGMP dependent protein kinase 1 | 0.0037 | 0.0346 | 0.0346 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.1704 | 0.1641 |
Toxoplasma gondii | protein kinase G AGC kinase family member PKG | 0.0037 | 0.0346 | 0.1448 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0346 | 0.0273 |
Trypanosoma brucei | phosphatidylinositol (3,5) kinase, putative | 0.0028 | 0.0075 | 0.0489 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0059 | 0.1037 | 0.6589 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0058 | 0.1003 | 1 |
Brugia malayi | N-terminal motif family protein | 0.0037 | 0.0346 | 0.0346 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0075 | 0.1534 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0055 | 0.0932 | 0.5872 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0055 | 0.0932 | 0.5872 |
Brugia malayi | RNA binding protein | 0.0074 | 0.1518 | 0.1518 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0055 | 0.0932 | 0.4579 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0302 | 0.8611 | 0.8611 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0037 | 0.0346 | 0.0346 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0035 | 0.0289 | 0.1465 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0075 | 0.1534 | 1 |
Loa Loa (eye worm) | AGC/PKG protein kinase | 0.0037 | 0.0346 | 0.0273 |
Trypanosoma cruzi | regulatory subunit of protein kinase a-like protein, putative | 0.0037 | 0.0346 | 0.1857 |
Trypanosoma brucei | Flagellar Member 6 | 0.0037 | 0.0346 | 0.2256 |
Brugia malayi | Cyclic-nucleotide gated cation channel, C. elegans tax-4 ortholog | 0.0037 | 0.0346 | 0.0346 |
Echinococcus multilocularis | potassium:sodium hyperpolarization activated | 0.0055 | 0.0913 | 0.0844 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.0055 | 0.0913 | 0.0913 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0055 | 0.0932 | 0.4579 |
Brugia malayi | Cyclic-nucleotide gated cation channel | 0.0055 | 0.0913 | 0.0913 |
Loa Loa (eye worm) | cyclic-nucleotide gated cation channel | 0.0055 | 0.0913 | 0.0844 |
Leishmania major | cyclic nucleotide-binding protein-like protein | 0.0037 | 0.0346 | 0.1857 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0088 | 0.1946 | 1 |
Trypanosoma brucei | phosphatidylinositol-4-phosphate 5-kinase, putative | 0.0028 | 0.0075 | 0.0489 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0088 | 0.1946 | 1 |
Brugia malayi | FYVE finger-containing phosphoinositide kinase, putative | 0.0028 | 0.0075 | 0.0075 |
Schistosoma mansoni | hyperpolarization activated cyclic nucleotide-gated potassium channel | 0.0055 | 0.0913 | 0.0913 |
Toxoplasma gondii | hypothetical protein | 0.003 | 0.0152 | 0.0411 |
Loa Loa (eye worm) | cAMP-dependent protein kinase regulatory subunit | 0.0037 | 0.0346 | 0.0273 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0055 | 0.0932 | 0.5872 |
Trypanosoma cruzi | regulatory subunit of protein kinase a-like protein, putative | 0.0037 | 0.0346 | 0.1857 |
Echinococcus multilocularis | cAMP dependent protein kinase type I beta | 0.0037 | 0.0346 | 0.0273 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0075 | 0.1534 | 1 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0035 | 0.0289 | 0.0289 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0236 | 0.0236 |
Treponema pallidum | catabolite gene activator | 0.0037 | 0.0346 | 0.1081 |
Echinococcus multilocularis | cyclic nucleotide gated cation channel | 0.0055 | 0.0913 | 0.0844 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.008 | 0.1704 | 0.1704 |
Plasmodium falciparum | cGMP-dependent protein kinase | 0.0037 | 0.0346 | 0.1448 |
Trypanosoma cruzi | protein kinase A regulatory subunit | 0.0037 | 0.0346 | 0.1857 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0037 | 0.0346 | 0.0346 |
Trypanosoma cruzi | Flagellar Member 6 | 0.0037 | 0.0346 | 0.1857 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0075 | 0.1534 | 1 |
Echinococcus multilocularis | cAMP dependent protein kinase type II regulatory | 0.0037 | 0.0346 | 0.0273 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0259 | 0.7253 | 1 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.003 | 0.0152 | 0.0411 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0035 | 0.0289 | 0.0215 |
Schistosoma mansoni | hyperpolarization activated cyclic nucleotide-gated potassium channel | 0.0037 | 0.0346 | 0.0346 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0104 | 0.2455 | 0.2455 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0068 | 0.1332 | 0.8617 |
Toxoplasma gondii | cyclic nucleotide-binding domain-containing protein | 0.0037 | 0.0346 | 0.1448 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0075 | 0.1534 | 1 |
Plasmodium vivax | rap guanine nucleotide exchange factor, putative | 0.0037 | 0.0346 | 0.1448 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0321 | 0.0321 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0075 | 0.1534 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0033 | 0.0236 | 0.0236 |
Echinococcus multilocularis | cyclic nucleotide gated cation channel alpha 3 | 0.0055 | 0.0913 | 0.0844 |
Echinococcus multilocularis | tar DNA binding protein | 0.0074 | 0.1518 | 0.1454 |
Brugia malayi | Probable ClpP-like protease | 0.0088 | 0.1946 | 0.1946 |
Schistosoma mansoni | 60S ribosomal protein L21 | 0.0044 | 0.0567 | 0.0567 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0033 | 0.0236 | 0.0236 |
Brugia malayi | Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog | 0.008 | 0.1704 | 0.1704 |
Schistosoma mansoni | tar DNA-binding protein | 0.0074 | 0.1518 | 0.1518 |
Schistosoma mansoni | camp-dependent protein kinase regulatory chain | 0.0037 | 0.0346 | 0.0346 |
Loa Loa (eye worm) | hypothetical protein | 0.024 | 0.6683 | 0.6658 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.2455 | 0.2397 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0074 | 0.1518 | 0.1454 |
Echinococcus granulosus | cGMP dependent protein kinase | 0.0037 | 0.0346 | 0.0346 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0104 | 0.2455 | 0.2455 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0236 | 0.0236 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0055 | 0.0913 | 0.1258 |
Brugia malayi | MH2 domain containing protein | 0.0255 | 0.7135 | 0.7135 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0277 | 0.782 | 0.7803 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0088 | 0.1946 | 0.1946 |
Echinococcus granulosus | cyclic nucleotide gated cation channel | 0.0055 | 0.0913 | 0.0913 |
Echinococcus granulosus | cGMP dependent protein kinase 1 | 0.0037 | 0.0346 | 0.0346 |
Leishmania major | cathepsin L-like protease | 0.0075 | 0.1534 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0075 | 0.1534 | 1 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0277 | 0.782 | 0.782 |
Brugia malayi | isocitrate dehydrogenase | 0.0035 | 0.0289 | 0.0289 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0088 | 0.1946 | 1 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0088 | 0.1946 | 1 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0037 | 0.0346 | 0.1778 |
Leishmania major | hypothetical protein, conserved | 0.0037 | 0.0346 | 0.1857 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0035 | 0.0289 | 0.1142 |
Loa Loa (eye worm) | TAR-binding protein | 0.0074 | 0.1518 | 0.1454 |
Echinococcus multilocularis | hyperpolarization activated cyclic | 0.0055 | 0.0913 | 0.0844 |
Entamoeba histolytica | phosphatidylinositol-4-phosphate 5-kinase, putative | 0.0028 | 0.0075 | 0.5 |
Leishmania major | regulatory subunit of protein kinase a-like protein | 0.0037 | 0.0346 | 0.1857 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0058 | 0.1003 | 0.1003 |
Schistosoma mansoni | neuropathy target esterase/swiss cheese-related protein | 0.0037 | 0.0346 | 0.0346 |
Echinococcus multilocularis | GPCR, family 2 | 0.0033 | 0.0236 | 0.0162 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0088 | 0.1946 | 0.5 |
Schistosoma mansoni | voltage-gated potassium channel | 0.008 | 0.1704 | 0.1704 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.003 | 0.0152 | 0.0411 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0058 | 0.1003 | 1 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0055 | 0.0932 | 0.4579 |
Entamoeba histolytica | phosphoinositide kinase, putative | 0.0028 | 0.0075 | 0.5 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0255 | 0.7135 | 0.7113 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0037 | 0.0346 | 0.0801 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0037 | 0.0346 | 0.0477 |
Brugia malayi | Pip kinase protein 1 | 0.0028 | 0.0075 | 0.0075 |
Echinococcus granulosus | potassium:sodium hyperpolarization activated | 0.0055 | 0.0913 | 0.0913 |
Trichomonas vaginalis | phosphatidylinositol-4-phosphate 5-kinase type II, putative | 0.0028 | 0.0075 | 0.0104 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0058 | 0.1003 | 0.0935 |
Echinococcus multilocularis | expressed conserved protein | 0.0037 | 0.0346 | 0.0273 |
Brugia malayi | Hypothetical UPF0028 protein ZK370.4 in chromosome III, putative | 0.0037 | 0.0346 | 0.0346 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0088 | 0.1946 | 1 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0055 | 0.0932 | 0.4579 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0033 | 0.0236 | 0.0162 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0071 | 0.1428 | 0.1428 |
Plasmodium falciparum | cAMP-dependent protein kinase regulatory subunit | 0.0037 | 0.0346 | 0.1448 |
Mycobacterium tuberculosis | Probable conserved transmembrane transport protein | 0.0037 | 0.0346 | 0.0801 |
Schistosoma mansoni | phosphatidylinositol-4-phosphate 5-kinase type II | 0.0028 | 0.0075 | 0.0075 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0259 | 0.7253 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0255 | 0.7135 | 0.7113 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0035 | 0.0289 | 0.1142 |
Echinococcus multilocularis | voltage gated potassium channel | 0.008 | 0.1704 | 0.1641 |
Treponema pallidum | catabolite gene activator (Crp) | 0.0037 | 0.0346 | 0.1081 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0236 | 0.0236 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0346 | 0.1857 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0075 | 0.1534 | 1 |
Trichomonas vaginalis | phosphatidylinositol-4-phosphate 5-kinase type II, putative | 0.0028 | 0.0075 | 0.0104 |
Giardia lamblia | CAMP-dependent protein kinase regulatory chain | 0.0037 | 0.0346 | 1 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0088 | 0.1946 | 1 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0035 | 0.0289 | 0.1465 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0033 | 0.0236 | 0.0236 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0088 | 0.1946 | 1 |
Trypanosoma brucei | cAMP response protein 1, putative | 0.0037 | 0.0346 | 0.2256 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0055 | 0.0932 | 0.6074 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0075 | 0.1534 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0075 | 0.1534 | 1 |
Toxoplasma gondii | cyclic nucleotide-binding domain-containing protein | 0.0037 | 0.0346 | 0.1448 |
Echinococcus multilocularis | cyclic nucleotide gated cation channel | 0.0037 | 0.0346 | 0.0273 |
Echinococcus multilocularis | cGMP dependent protein kinase 1 | 0.0037 | 0.0346 | 0.0273 |
Echinococcus multilocularis | hyperpolarization activated cyclic | 0.0055 | 0.0913 | 0.0844 |
Schistosoma mansoni | camp-dependent protein kinase type II-alpha regulatory subunit | 0.0037 | 0.0346 | 0.0346 |
Schistosoma mansoni | tar DNA-binding protein | 0.0074 | 0.1518 | 0.1518 |
Schistosoma mansoni | neuropathy target esterase/swiss cheese-related protein | 0.0037 | 0.0346 | 0.0346 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0104 | 0.2455 | 0.2397 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0033 | 0.0236 | 0.0236 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0346 | 0.0346 |
Trypanosoma brucei | phosphatidylinositol phosphate kinase alpha | 0.0028 | 0.0075 | 0.0489 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0088 | 0.1946 | 0.1885 |
Echinococcus multilocularis | cGMP dependent protein kinase 1 | 0.0037 | 0.0346 | 0.0273 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0035 | 0.0289 | 0.0289 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0932 | 0.0863 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0075 | 0.1534 | 1 |
Schistosoma mansoni | camp-dependent protein kinase type I-beta regulatory subunit | 0.0037 | 0.0346 | 0.0346 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0346 | 0.0801 |
Brugia malayi | hypothetical protein | 0.0055 | 0.0932 | 0.0932 |
Schistosoma mansoni | tar DNA-binding protein | 0.0074 | 0.1518 | 0.1518 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0913 | 0.0844 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0035 | 0.0289 | 0.1465 |
Brugia malayi | Egg laying defective protein 4 | 0.0037 | 0.0346 | 0.0346 |
Schistosoma mansoni | hyperpolarization activated cyclic nucleotide-gated potassium channel | 0.0055 | 0.0913 | 0.0913 |
Treponema pallidum | cyclic nucleotide binding protein | 0.0037 | 0.0346 | 0.1081 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0035 | 0.0289 | 0.0215 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0033 | 0.0236 | 0.0162 |
Echinococcus granulosus | cyclic nucleotide gated cation channel alpha 3 | 0.0055 | 0.0913 | 0.0913 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0055 | 0.0913 | 0.1258 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0035 | 0.0289 | 0.0215 |
Leishmania major | hypothetical protein, unknown function | 0.0037 | 0.0346 | 0.1857 |
Schistosoma mansoni | tar DNA-binding protein | 0.0074 | 0.1518 | 0.1518 |
Brugia malayi | cAMP-dependent protein kinase regulatory chain, putative | 0.0037 | 0.0346 | 0.0346 |
Echinococcus granulosus | tar DNA binding protein | 0.0074 | 0.1518 | 0.1518 |
Echinococcus multilocularis | cAMP dependent protein kinase regulatory | 0.0037 | 0.0346 | 0.0273 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0236 | 0.0162 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0075 | 0.1534 | 1 |
Schistosoma mansoni | voltage-gated potassium channel | 0.008 | 0.1704 | 0.1704 |
Trichomonas vaginalis | cAMP-dependent protein kinase type I-beta regulatory subunit, putative | 0.0037 | 0.0346 | 0.0477 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.1428 | 0.1363 |
Mycobacterium tuberculosis | Probable transcriptional regulatory protein Cmr | 0.0037 | 0.0346 | 0.0801 |
Echinococcus multilocularis | patatin phospholipase domain containing protein | 0.0037 | 0.0346 | 0.0273 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0302 | 0.8611 | 0.8611 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0035 | 0.0289 | 0.0215 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0088 | 0.1946 | 1 |
Loa Loa (eye worm) | cyclic-nucleotide gated cation channel | 0.0055 | 0.0913 | 0.0844 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0055 | 0.0913 | 0.0913 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0075 | 0.1534 | 1 |
Mycobacterium leprae | ATP-dependent Clp protease proteolytic subunit 1 | 0.003 | 0.0152 | 0.0781 |
Schistosoma mansoni | similar to Protein C20orf152 homolog | 0.0037 | 0.0346 | 0.0346 |
Echinococcus granulosus | hyperpolarization activated cyclic | 0.0055 | 0.0913 | 0.0913 |
Schistosoma mansoni | camp-dependent rap1 guanine-nucleotide exchange factor | 0.0037 | 0.0346 | 0.0346 |
Trypanosoma cruzi | cAMP response protein 1 | 0.0037 | 0.0346 | 0.1857 |
Mycobacterium tuberculosis | Probable conserved transmembrane protein | 0.0037 | 0.0346 | 0.0801 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0037 | 0.0346 | 0.0346 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0035 | 0.0289 | 0.1883 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0044 | 0.0567 | 0.0567 |
Schistosoma mansoni | camp-dependent protein kinase type II regulatory subunit | 0.0037 | 0.0346 | 0.0346 |
Toxoplasma gondii | cAMP-dependent protein kinase regulatory subunit | 0.0037 | 0.0346 | 0.1448 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0035 | 0.0289 | 0.1142 |
Echinococcus multilocularis | cyclic nucleotide gated cation channel | 0.0037 | 0.0346 | 0.0273 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0037 | 0.0346 | 0.0477 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.0055 | 0.0913 | 0.0913 |
Leishmania major | protein kinase A regulatory subunit, putative | 0.0037 | 0.0346 | 0.1857 |
Mycobacterium tuberculosis | Probable glutamine-transport ATP-binding protein ABC transporter GlnQ | 0.0037 | 0.0346 | 0.0801 |
Leishmania major | cathepsin L-like protease | 0.0075 | 0.1534 | 1 |
Schistosoma mansoni | phosphatidylinositol-4-phosphate 5-kinase type II | 0.0028 | 0.0075 | 0.0075 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0035 | 0.0289 | 0.0215 |
Loa Loa (eye worm) | RNA binding protein | 0.0074 | 0.1518 | 0.1454 |
Schistosoma mansoni | camp-dependent protein kinase type I-beta regulatory subunit | 0.0037 | 0.0346 | 0.0346 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0058 | 0.1003 | 0.5155 |
Loa Loa (eye worm) | hypothetical protein | 0.0088 | 0.1946 | 0.1885 |
Leishmania major | hypothetical protein, conserved | 0.0037 | 0.0346 | 0.1857 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0075 | 0.1534 | 1 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0088 | 0.1946 | 0.1946 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0033 | 0.0236 | 0.0236 |
Toxoplasma gondii | cyclic nucleotide-binding domain-containing protein | 0.0037 | 0.0346 | 0.1448 |
Trypanosoma cruzi | cAMP binding protein, putative | 0.0037 | 0.0346 | 0.1857 |
Echinococcus granulosus | cAMP dependent protein kinase regulatory | 0.0037 | 0.0346 | 0.0346 |
Echinococcus granulosus | cyclic nucleotide gated cation channel | 0.0037 | 0.0346 | 0.0346 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0035 | 0.0289 | 0.1142 |
Trichomonas vaginalis | cAMP-dependent protein kinase regulatory subunit, putative | 0.0037 | 0.0346 | 0.0477 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0033 | 0.0236 | 0.0162 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.008 | 0.1704 | 0.1641 |
Schistosoma mansoni | tar DNA-binding protein | 0.0074 | 0.1518 | 0.1518 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0037 | 0.0346 | 0.0477 |
Leishmania major | protein kinase, putative | 0.0037 | 0.0346 | 0.1857 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0075 | 0.1534 | 1 |
Echinococcus granulosus | voltage gated potassium channel | 0.008 | 0.1704 | 0.1704 |
Trypanosoma brucei | phosphatidylinositol-4-phosphate 5-kinase, putative | 0.0028 | 0.0075 | 0.0489 |
Leishmania major | cathepsin L-like protease | 0.0075 | 0.1534 | 1 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0035 | 0.0289 | 0.0215 |
Trypanosoma brucei | cyclic nucleotide-binding domain containing protein, putative | 0.0037 | 0.0346 | 0.2256 |
Leishmania major | protein kinase, putative | 0.0037 | 0.0346 | 0.1857 |
Trypanosoma brucei | protein kinase A regulatory subunit | 0.0037 | 0.0346 | 0.2256 |
Trypanosoma brucei | cAMP binding protein, putative | 0.0037 | 0.0346 | 0.2256 |
Schistosoma mansoni | cyclic nucleotide-gated ion channel | 0.0037 | 0.0346 | 0.0346 |
Echinococcus granulosus | cAMP dependent protein kinase type I beta | 0.0037 | 0.0346 | 0.0346 |
Schistosoma mansoni | phosphatidylinositol-4-phosphate-5-kinaseputativ e | 0.0028 | 0.0075 | 0.0075 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0037 | 0.0346 | 0.0801 |
Brugia malayi | TAR-binding protein | 0.0074 | 0.1518 | 0.1518 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.0055 | 0.0913 | 0.0913 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0088 | 0.1946 | 1 |
Echinococcus granulosus | patatin phospholipase domain containing protein | 0.0037 | 0.0346 | 0.0346 |
Toxoplasma gondii | cyclic nucleotide-binding domain-containing protein | 0.0037 | 0.0346 | 0.1448 |
Trypanosoma brucei | cyclic nucleotide-binding domain containing protein, putative | 0.0037 | 0.0346 | 0.2256 |
Echinococcus granulosus | Phosphatidylinositol 4 phosphate 5 kinase type 1 | 0.0028 | 0.0075 | 0.0075 |
Leishmania major | hypothetical protein, conserved | 0.0037 | 0.0346 | 0.1857 |
Trypanosoma cruzi | cyclic nucleotide-binding domain containing protein, putative | 0.0037 | 0.0346 | 0.1857 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0035 | 0.0289 | 0.1883 |
Echinococcus granulosus | phosphatidylinositol phosphate 5 kinase type III | 0.0028 | 0.0075 | 0.0075 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0074 | 0.1518 | 0.1518 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0236 | 0.0236 |
Schistosoma mansoni | hypothetical protein | 0.0071 | 0.1428 | 0.1428 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0346 | 0.0273 |
Echinococcus granulosus | hyperpolarization activated cyclic | 0.0055 | 0.0913 | 0.0913 |
Trypanosoma cruzi | cAMP response protein 1, putative | 0.0037 | 0.0346 | 0.1857 |
Echinococcus granulosus | cyclic nucleotide gated cation channel | 0.0055 | 0.0913 | 0.0913 |
Schistosoma mansoni | phosphatidylinositol-4-phosphate 5-kinase type I | 0.0028 | 0.0075 | 0.0075 |
Brugia malayi | Isocitrate dehydrogenase | 0.0035 | 0.0289 | 0.0289 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0277 | 0.782 | 0.7803 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0277 | 0.782 | 0.782 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | Activation of Shh pathway in mouse Shh-Light II cells assessed as induction of gli1 expression at 1 uM after 48 hrs by renilla luminescence assay | ChEMBL. | 22985958 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.