Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | cyclic nucleotide gated cation channel | 0.0024 | 0.0289 | 0.0321 |
Echinococcus granulosus | cyclic nucleotide gated cation channel alpha 3 | 0.0024 | 0.0289 | 0.0321 |
Brugia malayi | Cyclic-nucleotide gated cation channel | 0.0024 | 0.0289 | 0.0321 |
Echinococcus multilocularis | cyclic nucleotide gated cation channel alpha 3 | 0.0024 | 0.0289 | 0.0321 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0035 | 0.1287 | 0.143 |
Echinococcus multilocularis | cyclic nucleotide gated cation channel | 0.0024 | 0.0289 | 0.0321 |
Echinococcus granulosus | cyclic nucleotide gated cation channel | 0.0024 | 0.0289 | 0.0321 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.0024 | 0.0289 | 0.0289 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.0024 | 0.0289 | 0.0289 |
Echinococcus multilocularis | hyperpolarization activated cyclic | 0.0024 | 0.0289 | 0.0321 |
Echinococcus multilocularis | hyperpolarization activated cyclic | 0.0024 | 0.0289 | 0.0321 |
Loa Loa (eye worm) | cyclic-nucleotide gated cation channel | 0.0024 | 0.0289 | 0.0321 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0289 | 0.0321 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0035 | 0.1287 | 0.1287 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0122 | 0.9002 | 1 |
Echinococcus multilocularis | potassium:sodium hyperpolarization activated | 0.0024 | 0.0289 | 0.0321 |
Schistosoma mansoni | hyperpolarization activated cyclic nucleotide-gated potassium channel | 0.0024 | 0.0289 | 0.0289 |
Echinococcus granulosus | hyperpolarization activated cyclic | 0.0024 | 0.0289 | 0.0321 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.0024 | 0.0289 | 0.0289 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0024 | 0.0289 | 0.0289 |
Echinococcus multilocularis | voltage gated potassium channel | 0.0035 | 0.1287 | 0.143 |
Loa Loa (eye worm) | cyclic-nucleotide gated cation channel | 0.0024 | 0.0289 | 0.0321 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0035 | 0.1287 | 0.1287 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1287 | 0.143 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0122 | 0.9002 | 1 |
Echinococcus granulosus | potassium:sodium hyperpolarization activated | 0.0024 | 0.0289 | 0.0321 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0035 | 0.1287 | 0.143 |
Schistosoma mansoni | hyperpolarization activated cyclic nucleotide-gated potassium channel | 0.0024 | 0.0289 | 0.0289 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0114 | 0.8287 | 1 |
Echinococcus granulosus | hyperpolarization activated cyclic | 0.0024 | 0.0289 | 0.0321 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0122 | 0.9002 | 1 |
Echinococcus granulosus | voltage gated potassium channel | 0.0035 | 0.1287 | 0.143 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0114 | 0.8287 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.7568 | 0.8407 |
Brugia malayi | Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog | 0.0035 | 0.1287 | 0.143 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0122 | 0.9002 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.