Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | LGC-31 protein | 0.0037 | 0.0077 | 0.0114 |
Echinococcus granulosus | tar DNA binding protein | 0.0125 | 0.0889 | 0.1317 |
Brugia malayi | jmjC domain containing protein | 0.0056 | 0.0255 | 0.0379 |
Brugia malayi | jmjC domain containing protein | 0.0056 | 0.0255 | 0.0379 |
Trichomonas vaginalis | DNA topoisomerase II, putative | 0.0758 | 0.6719 | 1 |
Brugia malayi | TAR-binding protein | 0.0125 | 0.0889 | 0.1323 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0212 | 0.169 | 0.251 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0037 | 0.0077 | 0.0114 |
Trypanosoma brucei | DNA topoisomerase II beta, putative | 0.0678 | 0.5978 | 0.7346 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0068 | 0.037 | 0.0544 |
Brugia malayi | gamma-aminobutyric-acid receptor beta subunit precursor | 0.0037 | 0.0077 | 0.0114 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0048 | 0.0183 | 0.0085 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0043 | 0.0136 | 0.01 |
Schistosoma mansoni | phd/f-box containing protein | 0.0056 | 0.0255 | 0.0372 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0077 | 0.0114 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0064 | 0.0328 | 0.0232 |
Brugia malayi | glutathione reductase | 0.0048 | 0.0183 | 0.0272 |
Schistosoma mansoni | prokaryotic DNA topoisomerase | 0.008 | 0.048 | 0.0708 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0119 | 0.0834 | 0.0743 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.0037 | 0.0077 | 0.0107 |
Brugia malayi | DNA topoisomerase III beta-1 | 0.008 | 0.048 | 0.0715 |
Toxoplasma gondii | histone lysine demethylase JMJC1/KDM5D/JARID1D | 0.0056 | 0.0255 | 0.025 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0058 | 0.0274 | 0.0401 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0039 | 0.0098 | 0.0139 |
Trichomonas vaginalis | set domain proteins, putative | 0.0231 | 0.1864 | 0.2714 |
Brugia malayi | Cation transporter family protein | 0.0037 | 0.0077 | 0.0114 |
Mycobacterium tuberculosis | Two component sensor histidine kinase PrrB | 0.0043 | 0.0136 | 0.0038 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0178 | 0.0266 |
Leishmania major | heat shock protein 83-1 | 0.0043 | 0.0136 | 0.01 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0037 | 0.0077 | 0.0107 |
Plasmodium falciparum | basic transcription factor 3b, putative | 0.0034 | 0.0056 | 0.0051 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.0037 | 0.0077 | 0.0107 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0037 | 0.0077 | 0.0107 |
Echinococcus granulosus | peregrin | 0.0035 | 0.006 | 0.0083 |
Loa Loa (eye worm) | ligand-Gated ion Channel family member | 0.0037 | 0.0077 | 0.0114 |
Wolbachia endosymbiont of Brugia malayi | membrane associated signal transduction histidine kinase | 0.0043 | 0.0136 | 0.0038 |
Brugia malayi | follicle stimulating hormone receptor | 0.023 | 0.186 | 0.2768 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0064 | 0.0328 | 0.0482 |
Loa Loa (eye worm) | hypothetical protein | 0.0455 | 0.3928 | 0.5846 |
Mycobacterium ulcerans | two component sensor kinase MprB | 0.0043 | 0.0136 | 0.0038 |
Leishmania major | heat shock protein 83-1 | 0.0043 | 0.0136 | 0.01 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0212 | 0.169 | 0.251 |
Mycobacterium tuberculosis | Probable two component sensor kinase | 0.0043 | 0.0136 | 0.0038 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0039 | 0.0098 | 0.0094 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0037 | 0.0077 | 0.0107 |
Toxoplasma gondii | DNA topoisomerase family protein | 0.008 | 0.048 | 0.0476 |
Entamoeba histolytica | DNA topoisomerase III, putative | 0.008 | 0.048 | 0.0637 |
Plasmodium falciparum | glutathione reductase | 0.0048 | 0.0183 | 0.0178 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0044 | 0.0146 | 0.0135 |
Schistosoma mansoni | nAChR subunit | 0.0037 | 0.0077 | 0.0107 |
Plasmodium falciparum | DNA topoisomerase 3, putative | 0.008 | 0.048 | 0.0476 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0203 | 0.1606 | 0.2391 |
Echinococcus multilocularis | nicotinic acetylcholine receptor a11 subunit | 0.0037 | 0.0077 | 0.0107 |
Onchocerca volvulus | DNA topoisomerase 2 homolog | 0.0618 | 0.5426 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0456 | 0.0679 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0456 | 0.0679 |
Leishmania major | heat shock protein 83-1 | 0.0043 | 0.0136 | 0.01 |
Leishmania major | DNA topoisomerase 1A | 0.008 | 0.048 | 0.0526 |
Plasmodium vivax | DNA topoisomerase 3, putative | 0.008 | 0.048 | 0.0476 |
Echinococcus granulosus | geminin | 0.0167 | 0.1273 | 0.1889 |
Trypanosoma brucei | heat shock protein, putative | 0.0043 | 0.0136 | 0.01 |
Trichomonas vaginalis | mismatch repair protein Mlh1C (mutL homolog) | 0.0043 | 0.0136 | 0.012 |
Loa Loa (eye worm) | TOPoisomerase family member | 0.0758 | 0.6719 | 1 |
Brugia malayi | DNA topoisomerase III | 0.008 | 0.048 | 0.0715 |
Trichomonas vaginalis | endoplasmin, putative | 0.0043 | 0.0136 | 0.012 |
Onchocerca volvulus | 0.008 | 0.048 | 0.0877 | |
Echinococcus multilocularis | jumonji domain containing protein | 0.004 | 0.0109 | 0.0155 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0037 | 0.0077 | 0.0114 |
Schistosoma mansoni | lamin | 0.0053 | 0.0226 | 0.0329 |
Plasmodium falciparum | endoplasmin, putative | 0.0043 | 0.0136 | 0.0132 |
Echinococcus multilocularis | heat shock protein | 0.0043 | 0.0136 | 0.0196 |
Brugia malayi | Cytochrome P450 family protein | 0.0051 | 0.0211 | 0.0314 |
Echinococcus multilocularis | musashi | 0.0053 | 0.0226 | 0.0329 |
Plasmodium vivax | heat shock protein 86, putative | 0.0043 | 0.0136 | 0.0132 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0058 | 0.0274 | 0.0401 |
Trypanosoma brucei | heat shock protein, putative | 0.0043 | 0.0136 | 0.01 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0053 | 0.0224 | 0.0333 |
Schistosoma mansoni | nAChR subunit | 0.0037 | 0.0077 | 0.0107 |
Toxoplasma gondii | exonuclease III APE | 0.0039 | 0.0098 | 0.0094 |
Brugia malayi | intermediate filament protein | 0.0053 | 0.0226 | 0.0336 |
Brugia malayi | Cation transporter family protein | 0.0037 | 0.0077 | 0.0114 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0039 | 0.0098 | 0.0053 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0077 | 0.0114 |
Brugia malayi | jmjC domain containing protein | 0.0056 | 0.0255 | 0.0379 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0039 | 0.0098 | 0.0064 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.011 | 0.075 | 0.0658 |
Mycobacterium ulcerans | DNA topoisomerase I | 0.008 | 0.048 | 0.0386 |
Echinococcus granulosus | JmjC domain containing protein 4 | 0.0056 | 0.0255 | 0.0372 |
Trichomonas vaginalis | sensor histidine kinase, putative | 0.0043 | 0.0136 | 0.012 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0037 | 0.0077 | 0.0114 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.0839 | 0.1248 |
Brugia malayi | excitatory GABA receptor EXP-1A | 0.0037 | 0.0077 | 0.0114 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0043 | 0.0136 | 0.0208 |
Leishmania major | hypothetical protein, conserved | 0.0043 | 0.0136 | 0.01 |
Echinococcus granulosus | nicotinic acetylcholine receptor beta 1 subunit | 0.0037 | 0.0077 | 0.0107 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0048 | 0.0183 | 0.0157 |
Trypanosoma cruzi | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative | 0.0043 | 0.0136 | 0.01 |
Brugia malayi | Cation transporter family protein | 0.0037 | 0.0077 | 0.0114 |
Mycobacterium tuberculosis | DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) | 0.0809 | 0.7186 | 0.7158 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0077 | 0.0114 |
Trypanosoma cruzi | mitochondrial DNA topoisomerase II, putative | 0.0911 | 0.8118 | 1 |
Brugia malayi | PHD-finger family protein | 0.0031 | 0.0021 | 0.0032 |
Schistosoma mansoni | ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related | 0.0056 | 0.0255 | 0.0372 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0064 | 0.0328 | 0.0489 |
Trypanosoma cruzi | Heat shock protein 83, putative | 0.0043 | 0.0136 | 0.01 |
Giardia lamblia | Pms1-like protein | 0.0043 | 0.0136 | 0.0208 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0029 | 0.0007 | 0.0003 |
Mycobacterium tuberculosis | Possible two component sensor kinase | 0.0043 | 0.0136 | 0.0038 |
Echinococcus granulosus | lamin | 0.0053 | 0.0226 | 0.0329 |
Plasmodium vivax | endoplasmin, putative | 0.0043 | 0.0136 | 0.0132 |
Echinococcus multilocularis | geminin | 0.0167 | 0.1273 | 0.1889 |
Leishmania major | heat shock protein 83-1 | 0.0043 | 0.0136 | 0.01 |
Schistosoma mansoni | tar DNA-binding protein | 0.0125 | 0.0889 | 0.1317 |
Plasmodium falciparum | thioredoxin reductase | 0.0048 | 0.0183 | 0.0178 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0039 | 0.0098 | 0.0064 |
Trichomonas vaginalis | heat shock protein, putative | 0.0043 | 0.0136 | 0.012 |
Loa Loa (eye worm) | glutathione reductase | 0.0048 | 0.0183 | 0.0272 |
Onchocerca volvulus | 0.0037 | 0.0077 | 0.0133 | |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0119 | 0.0834 | 0.1235 |
Trypanosoma brucei | DNA topoisomerase II alpha, putative | 0.0678 | 0.5978 | 0.7346 |
Loa Loa (eye worm) | intermediate filament protein | 0.0053 | 0.0226 | 0.0336 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0039 | 0.0098 | 0.0146 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0212 | 0.169 | 0.251 |
Mycobacterium leprae | Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) | 0.023 | 0.1855 | 0.7314 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0043 | 0.0136 | 0.01 |
Trichomonas vaginalis | prokaryotic DNA topoisomerase, putative | 0.008 | 0.048 | 0.0637 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0056 | 0.0255 | 0.0246 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0119 | 0.0834 | 0.0743 |
Entamoeba histolytica | DNA topoisomerase III, putative | 0.008 | 0.048 | 0.0637 |
Echinococcus granulosus | DNA topoisomerase 3 alpha | 0.008 | 0.048 | 0.0708 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0029 | 0.0007 | 0.0004 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0038 | 0.009 | 0.0085 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.021 | 0.1671 | 0.2482 |
Schistosoma mansoni | DNA topoisomerase II | 0.0758 | 0.6719 | 1 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0038 | 0.009 | 0.0051 |
Echinococcus multilocularis | jumonji domain containing 1A | 0.0056 | 0.0255 | 0.0372 |
Plasmodium vivax | SET domain protein, putative | 0.0029 | 0.0007 | 0.0003 |
Trichomonas vaginalis | heat shock protein, putative | 0.0043 | 0.0136 | 0.012 |
Schistosoma mansoni | intermediate filament proteins | 0.0053 | 0.0226 | 0.0329 |
Loa Loa (eye worm) | ACC-1 protein | 0.0037 | 0.0077 | 0.0114 |
Brugia malayi | Bromodomain containing protein | 0.0045 | 0.0155 | 0.0231 |
Mycobacterium ulcerans | two component system membrane associated sensor kinase | 0.0043 | 0.0136 | 0.0038 |
Leishmania major | trypanothione reductase | 0.0048 | 0.0183 | 0.0157 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0048 | 0.0178 | 0.0259 |
Trypanosoma brucei | DNA topoisomerase III, putative | 0.008 | 0.048 | 0.0526 |
Toxoplasma gondii | ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein | 0.0533 | 0.4646 | 0.4644 |
Echinococcus granulosus | jumonji domain containing 1A | 0.0056 | 0.0255 | 0.0372 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0039 | 0.0098 | 0.0146 |
Onchocerca volvulus | 0.0231 | 0.1864 | 0.343 | |
Mycobacterium tuberculosis | Two component sensor kinase MprB | 0.0043 | 0.0136 | 0.0038 |
Schistosoma mansoni | ap endonuclease | 0.0039 | 0.0098 | 0.0139 |
Plasmodium falciparum | DNA topoisomerase VI, b subunit, putative | 0.0043 | 0.0136 | 0.0132 |
Trypanosoma cruzi | DNA topoisomerase III, putative | 0.008 | 0.048 | 0.0526 |
Echinococcus granulosus | DNA topoisomerase 2 alpha | 0.0758 | 0.6719 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0029 | 0.0007 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0136 | 0.0203 |
Plasmodium vivax | glutathione reductase, putative | 0.0048 | 0.0183 | 0.0178 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0039 | 0.0098 | 0.0139 |
Trypanosoma brucei | heat shock protein, putative | 0.0043 | 0.0136 | 0.01 |
Brugia malayi | Bromodomain containing protein | 0.0035 | 0.006 | 0.009 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0053 | 0.0226 | 0.0336 |
Trichomonas vaginalis | two component sensor and regulator histidine kinase bacteria, putative | 0.0043 | 0.0136 | 0.012 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0043 | 0.0136 | 0.01 |
Plasmodium vivax | JmjC domain containing protein | 0.0056 | 0.0255 | 0.025 |
Toxoplasma gondii | NAC domain-containing protein | 0.0034 | 0.0056 | 0.0051 |
Trypanosoma brucei | heat shock protein, putative | 0.0043 | 0.0136 | 0.01 |
Plasmodium vivax | hypothetical protein, conserved | 0.0043 | 0.0136 | 0.0132 |
Brugia malayi | hypothetical protein | 0.0119 | 0.0839 | 0.1248 |
Echinococcus multilocularis | nicotinic acetylcholine receptor beta 1 subunit | 0.0037 | 0.0077 | 0.0107 |
Onchocerca volvulus | 0.0037 | 0.0077 | 0.0133 | |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.011 | 0.075 | 0.0658 |
Brugia malayi | Pre-SET motif family protein | 0.0203 | 0.1606 | 0.2391 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0077 | 0.0114 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0048 | 0.0183 | 0.0272 |
Echinococcus granulosus | lysine specific demethylase 6a | 0.0056 | 0.0255 | 0.0372 |
Plasmodium vivax | basic transcription factor 3b, putative | 0.0034 | 0.0056 | 0.0051 |
Leishmania major | heat shock protein 83-1 | 0.0043 | 0.0136 | 0.01 |
Leishmania major | heat shock protein 83-1 | 0.0043 | 0.0136 | 0.01 |
Chlamydia trachomatis | DNA topoisomerase I | 0.008 | 0.048 | 0.0349 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0043 | 0.0136 | 0.01 |
Trypanosoma cruzi | DNA topoisomerase II, putative | 0.0678 | 0.5978 | 0.7346 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.018 | 0.0268 |
Trypanosoma brucei | heat shock protein, putative | 0.0043 | 0.0136 | 0.01 |
Leishmania major | heat shock protein 83-1 | 0.0043 | 0.0136 | 0.01 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0269 | 0.2218 | 0.3297 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0119 | 0.0834 | 0.0965 |
Echinococcus multilocularis | nicotinic acetylcholine receptor alpha subunit | 0.0037 | 0.0077 | 0.0107 |
Loa Loa (eye worm) | ACC-1 protein | 0.0037 | 0.0077 | 0.0114 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0144 | 0.1063 | 0.1577 |
Onchocerca volvulus | 0.0037 | 0.0077 | 0.0133 | |
Trypanosoma brucei | JmjC domain, hydroxylase, putative | 0.0056 | 0.0255 | 0.0246 |
Schistosoma mansoni | hypothetical protein | 0.0167 | 0.1273 | 0.1889 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0037 | 0.0077 | 0.0114 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0037 | 0.0077 | 0.0107 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0044 | 0.0146 | 0.0135 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0269 | 0.2218 | 0.3297 |
Loa Loa (eye worm) | DNA topoisomerase III | 0.008 | 0.048 | 0.0715 |
Trypanosoma cruzi | DNA topoisomerase IA, putative | 0.008 | 0.048 | 0.0526 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0455 | 0.3923 | 0.5836 |
Toxoplasma gondii | DNA topoisomerase domain-containing protein | 0.008 | 0.048 | 0.0476 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0255 | 0.0379 |
Schistosoma mansoni | tar DNA-binding protein | 0.0125 | 0.0889 | 0.1317 |
Trypanosoma brucei | DNA topoisomerase ii | 0.0911 | 0.8118 | 1 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit alpha 8 | 0.0037 | 0.0077 | 0.0107 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0077 | 0.0114 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0051 | 0.0211 | 0.0314 |
Trypanosoma cruzi | DNA topoisomerase IA, putative | 0.008 | 0.048 | 0.0526 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.011 | 0.075 | 0.0658 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0077 | 0.0114 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0037 | 0.0077 | 0.0114 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0007 | 0.0004 |
Mycobacterium leprae | Probable DNA topoisomerase I TopA (omega-protein) (relaxing enzyme) (untwisting enzyme) (swivelase) (type I DNA topoisomerase) ( | 0.008 | 0.048 | 0.1464 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0044 | 0.0146 | 0.021 |
Toxoplasma gondii | ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein | 0.0043 | 0.0136 | 0.0132 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0037 | 0.0077 | 0.0107 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0048 | 0.0183 | 0.0265 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.0839 | 0.1248 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0005 | 0.0007 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor alpha subunit | 0.0037 | 0.0077 | 0.0114 |
Echinococcus multilocularis | phd:f box containing protein | 0.0056 | 0.0255 | 0.0372 |
Echinococcus multilocularis | peregrin | 0.0035 | 0.006 | 0.0083 |
Echinococcus multilocularis | acetylcholine receptor subunit beta 1 | 0.0037 | 0.0077 | 0.0107 |
Echinococcus granulosus | lamin dm0 | 0.0053 | 0.0226 | 0.0329 |
Leishmania major | hypothetical protein, conserved | 0.0056 | 0.0255 | 0.0246 |
Schistosoma mansoni | phosphatidylserine receptor | 0.0056 | 0.0255 | 0.0372 |
Leishmania major | heat shock protein 83-1 | 0.0043 | 0.0136 | 0.01 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0056 | 0.0255 | 0.0246 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0077 | 0.0114 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0043 | 0.0136 | 0.01 |
Echinococcus multilocularis | nAChR subunit | 0.0037 | 0.0077 | 0.0107 |
Giardia lamblia | DNA topoisomerase III | 0.008 | 0.048 | 0.0753 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0059 | 0.0287 | 0.0427 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0199 | 0.0296 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0037 | 0.0077 | 0.0107 |
Schistosoma mansoni | endoplasmin | 0.0043 | 0.0136 | 0.0196 |
Mycobacterium tuberculosis | Two component sensor histidine kinase TrcS | 0.0043 | 0.0136 | 0.0038 |
Onchocerca volvulus | 0.0053 | 0.0226 | 0.0407 | |
Echinococcus granulosus | glycine receptor subunit beta | 0.0037 | 0.0077 | 0.0107 |
Giardia lamblia | DNA topoisomerase III | 0.008 | 0.048 | 0.0753 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0119 | 0.0834 | 0.0743 |
Onchocerca volvulus | DNA topoisomerase 2 homolog | 0.0618 | 0.5426 | 1 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0043 | 0.0136 | 0.01 |
Echinococcus multilocularis | Pyruvate dehydrogenase (lipoamide) kinase | 0.0043 | 0.0136 | 0.0196 |
Brugia malayi | jmjC domain containing protein | 0.0212 | 0.169 | 0.2516 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0039 | 0.0098 | 0.0148 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0226 | 0.0336 |
Leishmania major | heat shock protein 83-1 | 0.0043 | 0.0136 | 0.01 |
Trypanosoma brucei | developmentally regulated phosphoprotein | 0.0043 | 0.0136 | 0.01 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0119 | 0.0834 | 0.0829 |
Chlamydia trachomatis | DNA gyrase subunit A | 0.0237 | 0.1918 | 0.1806 |
Trypanosoma brucei | trypanothione reductase | 0.0048 | 0.0183 | 0.0157 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0137 | 0.1003 | 0.1487 |
Brugia malayi | PHD-finger family protein | 0.0029 | 0.0005 | 0.0007 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0122 | 0.0863 | 0.0772 |
Trypanosoma cruzi | DNA topoisomerase II, putative | 0.0678 | 0.5978 | 0.7346 |
Trichomonas vaginalis | prokaryotic DNA topoisomerase, putative | 0.008 | 0.048 | 0.0637 |
Toxoplasma gondii | thioredoxin reductase | 0.0048 | 0.0183 | 0.0178 |
Echinococcus granulosus | heat shock protein 90 | 0.0043 | 0.0136 | 0.0196 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0455 | 0.3923 | 0.5836 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0029 | 0.0007 | 0.0004 |
Mycobacterium ulcerans | two component sensory transduction histidine kinase MtrB | 0.0043 | 0.0136 | 0.0038 |
Toxoplasma gondii | histone lysine demethylase JMJD6a | 0.0056 | 0.0255 | 0.025 |
Schistosoma mansoni | hypothetical protein | 0.0167 | 0.1273 | 0.1889 |
Mycobacterium ulcerans | two component system response phosphate sensor kinase, PhoR | 0.0043 | 0.0136 | 0.0038 |
Leishmania major | heat shock protein 83-1 | 0.0043 | 0.0136 | 0.01 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0217 | 0.0323 |
Echinococcus multilocularis | lamin dm0 | 0.0053 | 0.0226 | 0.0329 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0044 | 0.0146 | 0.0141 |
Brugia malayi | DNA gyrase/topoisomerase IV, A subunit family protein | 0.0758 | 0.6719 | 1 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0029 | 0.0005 | 0.0007 |
Brugia malayi | RNA binding protein | 0.0125 | 0.0889 | 0.1323 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.0037 | 0.0077 | 0.0107 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0064 | 0.0328 | 0.0338 |
Onchocerca volvulus | 0.0029 | 0.0007 | 0.0005 | |
Loa Loa (eye worm) | hypothetical protein | 0.0301 | 0.2507 | 0.3731 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0064 | 0.0328 | 0.0232 |
Schistosoma mansoni | heat shock protein | 0.0043 | 0.0136 | 0.0196 |
Leishmania major | heat shock protein 83-1 | 0.0043 | 0.0136 | 0.01 |
Onchocerca volvulus | 0.0053 | 0.0226 | 0.0407 | |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0039 | 0.01 | 0.0142 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0077 | 0.0114 |
Echinococcus multilocularis | Pyruvate dehydrogenase (lipoamide) kinase | 0.0043 | 0.0136 | 0.0196 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0043 | 0.0136 | 0.012 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.023 | 0.186 | 0.2768 |
Trypanosoma brucei | heat shock protein, putative | 0.0043 | 0.0136 | 0.01 |
Treponema pallidum | DNA topoisomerase I (topA) | 0.008 | 0.048 | 0.0386 |
Loa Loa (eye worm) | acetylcholine receptor alpha subunit | 0.0037 | 0.0077 | 0.0114 |
Loa Loa (eye worm) | hypothetical protein | 0.0301 | 0.2507 | 0.3731 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0039 | 0.0098 | 0.0094 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0043 | 0.0136 | 0.01 |
Schistosoma mansoni | transcription factor btf3 | 0.0034 | 0.0056 | 0.0076 |
Mycobacterium ulcerans | DNA gyrase subunit B | 0.0809 | 0.7186 | 0.7158 |
Schistosoma mansoni | nAChR subunit | 0.0037 | 0.0077 | 0.0107 |
Schistosoma mansoni | heat shock protein | 0.0043 | 0.0136 | 0.0196 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0077 | 0.0114 |
Brugia malayi | Thioredoxin reductase | 0.0048 | 0.0183 | 0.0272 |
Brugia malayi | nicotinic acetylcholine receptor beta-1 chain precursor | 0.0037 | 0.0077 | 0.0114 |
Echinococcus granulosus | nAChR subunit | 0.0037 | 0.0077 | 0.0107 |
Echinococcus multilocularis | DNA topoisomerase 2 alpha | 0.0758 | 0.6719 | 1 |
Trypanosoma brucei | Heat shock protein 83, putative | 0.0043 | 0.0136 | 0.01 |
Brugia malayi | beta-NAC-like protein | 0.0034 | 0.0056 | 0.0083 |
Mycobacterium ulcerans | two component sensor histidine kinase PrrB | 0.0043 | 0.0136 | 0.0038 |
Plasmodium vivax | DNA topoisomerase II, putative | 0.0758 | 0.6719 | 0.6717 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0144 | 0.1063 | 0.1577 |
Echinococcus granulosus | DNA topoisomerase 3 beta 1 | 0.008 | 0.048 | 0.0708 |
Toxoplasma gondii | DNA topoisomerase 2, putative | 0.0758 | 0.6719 | 0.6717 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit type | 0.0037 | 0.0077 | 0.0107 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0122 | 0.0863 | 0.309 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0048 | 0.0183 | 0.0178 |
Schistosoma mansoni | nAChR subunit | 0.0037 | 0.0077 | 0.0107 |
Treponema pallidum | DNA gyrase, subunit B (gyrB) | 0.0809 | 0.7186 | 0.7158 |
Leishmania major | DNA topoisomerase ii | 0.0678 | 0.5978 | 0.7346 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0122 | 0.0863 | 0.0772 |
Onchocerca volvulus | 0.0037 | 0.0077 | 0.0133 | |
Leishmania major | mitochondrial DNA topoisomerase II | 0.0911 | 0.8118 | 1 |
Schistosoma mansoni | nAChR subunit | 0.0037 | 0.0077 | 0.0107 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0039 | 0.0098 | 0.0053 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0048 | 0.0183 | 0.0265 |
Treponema pallidum | chemotaxis histidine kinase (cheA) | 0.0043 | 0.0136 | 0.0038 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0077 | 0.0114 |
Echinococcus granulosus | neuropeptide s receptor | 0.0455 | 0.3923 | 0.5836 |
Plasmodium falciparum | DNA topoisomerase 2 | 0.0758 | 0.6719 | 0.6717 |
Plasmodium falciparum | heat shock protein 90 | 0.0043 | 0.0136 | 0.0132 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0039 | 0.0098 | 0.0053 |
Toxoplasma gondii | ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein | 0.0043 | 0.0136 | 0.0132 |
Brugia malayi | kinase, mitochondrial precursor | 0.0043 | 0.0136 | 0.0203 |
Mycobacterium tuberculosis | Two component sensor histidine kinase DosT | 0.0043 | 0.0136 | 0.0038 |
Schistosoma mansoni | nAChR subunit | 0.0037 | 0.0077 | 0.0107 |
Chlamydia trachomatis | DNA gyrase subunit B | 0.0657 | 0.5787 | 0.5729 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0064 | 0.0328 | 0.0482 |
Trypanosoma brucei | DNA topoisomerase IA, putative | 0.008 | 0.048 | 0.0526 |
Giardia lamblia | DNA topoisomerase II | 0.0715 | 0.6322 | 1 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0048 | 0.0178 | 0.0259 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0037 | 0.0077 | 0.0114 |
Loa Loa (eye worm) | acetyltransferase | 0.0144 | 0.1063 | 0.1583 |
Mycobacterium tuberculosis | Two component sensory transduction histidine kinase MtrB | 0.0043 | 0.0136 | 0.0038 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.011 | 0.075 | 0.2611 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0077 | 0.0114 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0449 | 0.0668 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta2-like) | 0.0037 | 0.0077 | 0.0107 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0077 | 0.0114 |
Echinococcus multilocularis | lamin | 0.0053 | 0.0226 | 0.0329 |
Schistosoma mansoni | tar DNA-binding protein | 0.0125 | 0.0889 | 0.1317 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0037 | 0.0077 | 0.0107 |
Brugia malayi | acetylcholine receptor protein, alpha-like chain, putative | 0.0037 | 0.0077 | 0.0114 |
Brugia malayi | Probable DNA topoisomerase II | 0.0758 | 0.6719 | 1 |
Echinococcus multilocularis | neuronal acetylcholine receptor subunit alpha 4 | 0.0037 | 0.0077 | 0.0107 |
Brugia malayi | heat shock protein 90 | 0.0043 | 0.0136 | 0.0203 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0255 | 0.0379 |
Loa Loa (eye worm) | DNA topoisomerase III beta-1 | 0.008 | 0.048 | 0.0715 |
Brugia malayi | acetylcholine receptor alpha subunit precursor, putative | 0.0037 | 0.0077 | 0.0114 |
Onchocerca volvulus | 0.0037 | 0.0077 | 0.0133 | |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0048 | 0.0178 | 0.0259 |
Schistosoma mansoni | tar DNA-binding protein | 0.0125 | 0.0889 | 0.1317 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.0624 | 0.0928 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0056 | 0.0255 | 0.0379 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0053 | 0.0226 | 0.0336 |
Echinococcus granulosus | heat shock protein | 0.0043 | 0.0136 | 0.0196 |
Wolbachia endosymbiont of Brugia malayi | DNA gyrase, topoisomerase II, B subunit, GyrB | 0.0809 | 0.7186 | 0.7158 |
Mycobacterium tuberculosis | Two component sensor kinase [second part] | 0.0043 | 0.0136 | 0.0038 |
Wolbachia endosymbiont of Brugia malayi | signal transduction histidine kinase and receiver | 0.0043 | 0.0136 | 0.0038 |
Chlamydia trachomatis | DNA gyrase subunit B | 0.0809 | 0.7186 | 0.7147 |
Loa Loa (eye worm) | TAR-binding protein | 0.0125 | 0.0889 | 0.1323 |
Echinococcus granulosus | nicotinic acetylcholine receptor alpha subunit | 0.0037 | 0.0077 | 0.0107 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0119 | 0.0834 | 0.1235 |
Mycobacterium tuberculosis | Possible two component system response sensor kinase membrane associated PhoR | 0.0043 | 0.0136 | 0.0038 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor non-alpha subunit | 0.0037 | 0.0077 | 0.0114 |
Plasmodium vivax | DNA gyrase subunit B, putative | 0.0809 | 0.7186 | 0.7185 |
Trypanosoma brucei | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative | 0.0043 | 0.0136 | 0.01 |
Trypanosoma cruzi | DNA topoisomerase III, putative | 0.008 | 0.048 | 0.0526 |
Mycobacterium tuberculosis | Possible two component sensor kinase TcrY | 0.0043 | 0.0136 | 0.0038 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0037 | 0.0077 | 0.0107 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0056 | 0.0255 | 0.0379 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0119 | 0.0834 | 0.1235 |
Brugia malayi | acetylcholine receptor, alpha-type subunit unc-38 precursor | 0.0037 | 0.0077 | 0.0114 |
Schistosoma mansoni | tar DNA-binding protein | 0.0125 | 0.0889 | 0.1317 |
Mycobacterium tuberculosis | Two component sensor histidine kinase DevS | 0.0043 | 0.0136 | 0.0038 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0038 | 0.009 | 0.0135 |
Schistosoma mansoni | ap endonuclease | 0.0039 | 0.0098 | 0.0139 |
Echinococcus multilocularis | transcription factor btf3 | 0.0034 | 0.0056 | 0.0076 |
Onchocerca volvulus | 0.0037 | 0.0077 | 0.0133 | |
Trichomonas vaginalis | receptor histidine kinase, putative | 0.0043 | 0.0136 | 0.012 |
Brugia malayi | GRF zinc finger family protein | 0.008 | 0.048 | 0.0715 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0043 | 0.0136 | 0.012 |
Trypanosoma cruzi | developmentally regulated phosphoprotein, putative | 0.0043 | 0.0136 | 0.01 |
Trypanosoma brucei | heat shock protein, putative | 0.0043 | 0.0136 | 0.01 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0455 | 0.3923 | 0.5836 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0068 | 0.037 | 0.0544 |
Leishmania major | developmentally regulated phosphoprotein-like protein | 0.0043 | 0.0136 | 0.01 |
Leishmania major | DNA topoisomerase III, putative | 0.008 | 0.048 | 0.0526 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0077 | 0.0114 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0037 | 0.0077 | 0.0107 |
Mycobacterium tuberculosis | Conserved protein | 0.0043 | 0.0136 | 0.0038 |
Toxoplasma gondii | heat shock protein 90, putative | 0.0043 | 0.0136 | 0.0132 |
Onchocerca volvulus | Putative DNA topoisomerase 2, mitochondrial | 0.0618 | 0.5426 | 1 |
Trypanosoma brucei | DNA topoisomerase III, putative | 0.008 | 0.048 | 0.0526 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0037 | 0.0077 | 0.0107 |
Mycobacterium ulcerans | two component sensor histidine kinase DevS | 0.0043 | 0.0136 | 0.0038 |
Echinococcus multilocularis | lysine specific demethylase 6a | 0.0056 | 0.0255 | 0.0372 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0077 | 0.0114 |
Leishmania major | heat shock protein 83-1 | 0.0043 | 0.0136 | 0.01 |
Trichomonas vaginalis | sensory transduction histidine kinase bacterial, putative | 0.0043 | 0.0136 | 0.012 |
Echinococcus granulosus | transcription factor btf3 | 0.0034 | 0.0056 | 0.0076 |
Schistosoma mansoni | pyruvate dehydrogenase | 0.0043 | 0.0136 | 0.0196 |
Echinococcus multilocularis | DNA topoisomerase 3 beta 1 | 0.008 | 0.048 | 0.0708 |
Onchocerca volvulus | Putative nachr subunit | 0.0037 | 0.0077 | 0.0133 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0064 | 0.0328 | 0.0482 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit alpha 8 | 0.0037 | 0.0077 | 0.0107 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0039 | 0.01 | 0.0142 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0039 | 0.0098 | 0.0053 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.011 | 0.075 | 0.0658 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0077 | 0.0114 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0144 | 0.1063 | 0.1583 |
Loa Loa (eye worm) | RNA binding protein | 0.0125 | 0.0889 | 0.1323 |
Mycobacterium ulcerans | two component regulator - sensor kinase | 0.0043 | 0.0136 | 0.0038 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0037 | 0.0077 | 0.0114 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0124 | 0.0185 |
Plasmodium falciparum | JmjC domain-containing protein, putative | 0.0056 | 0.0255 | 0.025 |
Trypanosoma cruzi | mitochondrial DNA topoisomerase II, putative | 0.0911 | 0.8118 | 1 |
Schistosoma mansoni | prokaryotic DNA topoisomerase | 0.008 | 0.048 | 0.0708 |
Brugia malayi | jmjC domain containing protein | 0.0269 | 0.2218 | 0.3302 |
Schistosoma mansoni | lamin | 0.0053 | 0.0226 | 0.0329 |
Toxoplasma gondii | heat shock protein HSP90 | 0.0043 | 0.0136 | 0.0132 |
Loa Loa (eye worm) | glutamate-gated chloride channel alpha3A subunit | 0.0037 | 0.0077 | 0.0114 |
Brugia malayi | jmjC domain containing protein | 0.0056 | 0.0255 | 0.0379 |
Schistosoma mansoni | jumonji domain containing protein | 0.0056 | 0.0255 | 0.0372 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0077 | 0.0114 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0125 | 0.0889 | 0.1323 |
Echinococcus multilocularis | heat shock protein 90 | 0.0043 | 0.0136 | 0.0196 |
Schistosoma mansoni | protein phosphatase 2C | 0.0056 | 0.0255 | 0.0372 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0037 | 0.0077 | 0.0114 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0125 | 0.0889 | 0.1323 |
Brugia malayi | Endoplasmin precursor | 0.0043 | 0.0136 | 0.0203 |
Echinococcus granulosus | jumonji domain containing protein | 0.004 | 0.0109 | 0.0155 |
Trichomonas vaginalis | sensory transduction histidine kinase bacterial, putative | 0.0043 | 0.0136 | 0.012 |
Mycobacterium leprae | Probable DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) | 0.0299 | 0.2487 | 1 |
Onchocerca volvulus | Huntingtin homolog | 0.0119 | 0.0839 | 0.1538 |
Schistosoma mansoni | nAChR subunit | 0.0037 | 0.0077 | 0.0107 |
Echinococcus granulosus | nicotinic acetylcholine receptor a11 subunit | 0.0037 | 0.0077 | 0.0107 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0037 | 0.0077 | 0.0107 |
Mycobacterium ulcerans | putative regultory protein | 0.0043 | 0.0136 | 0.0038 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0077 | 0.0114 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.0037 | 0.0077 | 0.0107 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0064 | 0.0328 | 0.0232 |
Entamoeba histolytica | DNA topoisomerase II, putative | 0.0758 | 0.6719 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0043 | 0.0136 | 0.01 |
Trichomonas vaginalis | sensory transduction histidine kinase, putative | 0.0043 | 0.0136 | 0.012 |
Brugia malayi | DNA topoisomerase II, alpha isozyme | 0.0758 | 0.6719 | 1 |
Trypanosoma brucei | heat shock protein, putative | 0.0043 | 0.0136 | 0.01 |
Leishmania major | heat shock protein 83-1 | 0.0043 | 0.0136 | 0.01 |
Trichomonas vaginalis | receptor histidine kinase, putative | 0.0043 | 0.0136 | 0.012 |
Echinococcus multilocularis | tar DNA binding protein | 0.0125 | 0.0889 | 0.1317 |
Loa Loa (eye worm) | excitatory GABA receptor EXP-1A | 0.0037 | 0.0077 | 0.0114 |
Loa Loa (eye worm) | ICD-1 protein | 0.0034 | 0.0056 | 0.0083 |
Schistosoma mansoni | bromodomain containing protein | 0.0072 | 0.0406 | 0.0597 |
Leishmania major | heat shock protein 83-1 | 0.0043 | 0.0136 | 0.01 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0119 | 0.0834 | 0.1235 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0119 | 0.0834 | 0.0743 |
Brugia malayi | Bromodomain containing protein | 0.0085 | 0.0523 | 0.0779 |
Mycobacterium tuberculosis | Probable sensor protein KdpD | 0.0043 | 0.0136 | 0.0038 |
Mycobacterium ulcerans | two component sensor histidine kinase SenX3 | 0.0043 | 0.0136 | 0.0038 |
Onchocerca volvulus | Huntingtin homolog | 0.0119 | 0.0839 | 0.1538 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0039 | 0.0098 | 0.0064 |
Mycobacterium tuberculosis | Probable reductase | 0.011 | 0.075 | 0.0658 |
Echinococcus granulosus | neuronal acetylcholine receptor subunit alpha 4 | 0.0037 | 0.0077 | 0.0107 |
Loa Loa (eye worm) | hypothetical protein | 0.0455 | 0.3928 | 0.5846 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0077 | 0.0114 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0456 | 0.0679 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0056 | 0.0255 | 0.0379 |
Loa Loa (eye worm) | endoplasmin | 0.0043 | 0.0136 | 0.0203 |
Leishmania major | heat shock protein 83-1 | 0.0043 | 0.0136 | 0.01 |
Echinococcus granulosus | intermediate filament protein | 0.0053 | 0.0226 | 0.0329 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0037 | 0.0077 | 0.0114 |
Loa Loa (eye worm) | heat shock protein 90 | 0.0043 | 0.0136 | 0.0203 |
Echinococcus granulosus | phd:f box containing protein | 0.0056 | 0.0255 | 0.0372 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0212 | 0.169 | 0.2516 |
Leishmania major | heat shock protein 83-1 | 0.0043 | 0.0136 | 0.01 |
Plasmodium falciparum | DNA gyrase subunit B | 0.0809 | 0.7186 | 0.7185 |
Echinococcus multilocularis | rho GTPase activating protein 20 | 0.008 | 0.048 | 0.0708 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0037 | 0.0077 | 0.0114 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0044 | 0.0146 | 0.0141 |
Schistosoma mansoni | endoplasmin | 0.0043 | 0.0136 | 0.0196 |
Echinococcus multilocularis | JmjC domain containing protein 4 | 0.0056 | 0.0255 | 0.0372 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.011 | 0.075 | 0.0658 |
Brugia malayi | nicotinic acetylcholine receptor alpha subunit, putative | 0.0037 | 0.0077 | 0.0114 |
Wolbachia endosymbiont of Brugia malayi | topoisomerase IA, TopA | 0.008 | 0.048 | 0.0386 |
Mycobacterium ulcerans | two component sensor histidine kinase TrcS | 0.0043 | 0.0136 | 0.0038 |
Echinococcus granulosus | Pyruvate dehydrogenase lipoamide kinase | 0.0043 | 0.0136 | 0.0196 |
Leishmania major | DNA topoisomerase III, putative | 0.008 | 0.048 | 0.0526 |
Echinococcus granulosus | acetylcholine receptor subunit beta 1 | 0.0037 | 0.0077 | 0.0107 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0048 | 0.0178 | 0.0259 |
Mycobacterium ulcerans | sensor kinase from two component regulatory system | 0.0043 | 0.0136 | 0.0038 |
Schistosoma mansoni | jumonji domain containing protein | 0.025 | 0.204 | 0.3031 |
Trypanosoma cruzi | DNA topoisomerase III, putative | 0.008 | 0.048 | 0.0526 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0044 | 0.0146 | 0.0141 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0037 | 0.0077 | 0.0107 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0122 | 0.0863 | 0.0772 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0077 | 0.0114 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | > 30 uM | Inhibition of ATR-mediated CHK1 phosphorylation at serine 345 in human HT29 cells after 1 hr in presence of 4-nitroquinoline 1-oxide | ChEMBL. | 23394205 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.