Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | larval opioid receptor | 0.0017 | 0.0014 | 0.0018 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0017 | 0.0014 | 0.0018 |
Giardia lamblia | O-linked GlcNAc transferase | 0.0039 | 0.031 | 1 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0018 | 0.003 | 0.0027 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | o-linked n-acetylglucosamine transferase ogt | 0.004 | 0.0316 | 0.0312 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | uridine 5' monophosphate synthase | 0.0062 | 0.0607 | 0.0604 |
Echinococcus multilocularis | 6 phosphofructokinase | 0.0105 | 0.1168 | 0.1165 |
Trypanosoma brucei | orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative | 0.0062 | 0.0607 | 0.1432 |
Treponema pallidum | NADH oxidase | 0.0016 | 0.0004 | 0.0033 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | neuropeptide receptor | 0.0017 | 0.0014 | 0.001 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0116 | 0.1309 | 0.2354 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0042 | 0.0347 | 0.0343 |
Brugia malayi | AKH receptor | 0.0017 | 0.0014 | 0.0018 |
Schistosoma mansoni | myosin xvIII | 0.0017 | 0.0014 | 0.001 |
Trypanosoma cruzi | orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative | 0.0062 | 0.0607 | 0.1432 |
Trypanosoma cruzi | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0105 | 0.1168 | 0.2763 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0105 | 0.1168 | 0.2085 |
Schistosoma mansoni | neuropeptide receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | allatostatin A receptor | 0.0017 | 0.0014 | 0.001 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0105 | 0.1158 | 0.2081 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0017 | 0.0014 | 0.001 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0116 | 0.1309 | 0.2354 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.0028 | 0.0168 | 0.0388 |
Plasmodium falciparum | orotidine 5'-phosphate decarboxylase | 0.0062 | 0.0607 | 0.1432 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0028 | 0.0168 | 0.1434 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.034 | 0.4218 | 1 |
Schistosoma mansoni | histamine h1 receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | neuropeptide receptor | 0.0017 | 0.0014 | 0.001 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0018 | 0.003 | 0.003 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0017 | 0.0014 | 0.001 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0347 | 0.0601 |
Trypanosoma brucei | trypanothione reductase | 0.0046 | 0.0394 | 0.0925 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0042 | 0.0347 | 0.0814 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 0.0734 | 0.073 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0028 | 0.0168 | 0.1406 |
Schistosoma mansoni | amine GPCR | 0.0017 | 0.0014 | 0.001 |
Loa Loa (eye worm) | phosphofructokinase | 0.0105 | 0.1168 | 0.2085 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0042 | 0.0347 | 0.0814 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0105 | 0.1158 | 0.2081 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | 6-phosphofructokinase | 0.0105 | 0.1168 | 0.21 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0042 | 0.0347 | 0.0343 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | orexin receptor type 2 | 0.0017 | 0.0014 | 0.001 |
Mycobacterium ulcerans | lipase LipD | 0.0042 | 0.0347 | 0.0619 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0014 | 0.0018 |
Schistosoma mansoni | opsin-like receptor | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0014 | 0.0018 |
Schistosoma mansoni | alzheimer's disease beta-amyloid related | 0.0122 | 0.1384 | 0.1381 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0014 | 0.001 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0028 | 0.0168 | 0.1406 |
Echinococcus granulosus | GPCR family 2 | 0.0018 | 0.003 | 0.0027 |
Plasmodium vivax | hypothetical protein, conserved | 0.0042 | 0.0347 | 0.0814 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.0028 | 0.0168 | 0.0388 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0017 | 0.0014 | 0.001 |
Loa Loa (eye worm) | glutathione reductase | 0.0046 | 0.0394 | 0.0686 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0042 | 0.0347 | 0.0619 |
Echinococcus granulosus | somatostatin receptor | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | phosphofructokinase | 0.0105 | 0.1168 | 0.21 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0014 | 0.0018 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0717 | 0.1271 |
Trichomonas vaginalis | conserved hypothetical protein | 0.005 | 0.0446 | 0.3796 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0014 | 0.0018 |
Echinococcus multilocularis | GPCR, family 2 | 0.0018 | 0.003 | 0.0027 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0017 | 0.0014 | 0.001 |
Toxoplasma gondii | 6-phosphofructokinase | 0.0028 | 0.0168 | 0.0388 |
Brugia malayi | neuropeptide F receptor | 0.0017 | 0.0014 | 0.0018 |
Leishmania major | orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative,OMPDCase-OPRTase, putative | 0.0062 | 0.0607 | 0.1432 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0017 | 0.0014 | 0.0018 |
Schistosoma mansoni | amine GPCR | 0.0017 | 0.0014 | 0.001 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0105 | 0.1168 | 1 |
Loa Loa (eye worm) | thymidylate synthase | 0.0105 | 0.1161 | 0.2071 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Entamoeba histolytica | hypothetical protein | 0.0083 | 0.0878 | 0.7104 |
Echinococcus multilocularis | O glycosyltransferase | 0.004 | 0.0316 | 0.0312 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0042 | 0.0347 | 0.0601 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0083 | 0.0878 | 0.0875 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0028 | 0.0168 | 0.1406 |
Wolbachia endosymbiont of Brugia malayi | orotidine-5'-phosphate decarboxylase | 0.0626 | 0.7948 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0042 | 0.0347 | 0.0619 |
Mycobacterium tuberculosis | Probable reductase | 0.0105 | 0.1158 | 0.2081 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0105 | 0.1161 | 0.1157 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0347 | 0.0601 |
Echinococcus multilocularis | uridine 5' monophosphate synthase | 0.0062 | 0.0607 | 0.0604 |
Onchocerca volvulus | 0.0042 | 0.0347 | 0.0467 | |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.003 | 0.003 |
Echinococcus granulosus | neuropeptide s receptor | 0.0017 | 0.0014 | 0.001 |
Loa Loa (eye worm) | UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltransferase | 0.004 | 0.0314 | 0.0542 |
Brugia malayi | GnHR receptor homolog | 0.0017 | 0.0014 | 0.0018 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0017 | 0.0014 | 0.001 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0046 | 0.0394 | 0.0925 |
Loa Loa (eye worm) | orotate phosphoribosyltransferase | 0.0062 | 0.0607 | 0.1072 |
Echinococcus multilocularis | g protein coupled receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Mycobacterium leprae | PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) | 0.0105 | 0.1168 | 0.1579 |
Brugia malayi | Serotonin receptor | 0.0017 | 0.0014 | 0.0018 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0017 | 0.0014 | 0.001 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0105 | 0.1168 | 1 |
Brugia malayi | Melatonin receptor type 1A | 0.0017 | 0.0014 | 0.0018 |
Toxoplasma gondii | ABC1 family protein | 0.0042 | 0.0347 | 0.0814 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0105 | 0.1168 | 1 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0017 | 0.0014 | 0.001 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0042 | 0.0347 | 0.0619 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0046 | 0.0394 | 0.039 |
Toxoplasma gondii | thioredoxin reductase | 0.0046 | 0.0394 | 0.0925 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0347 | 0.0601 |
Brugia malayi | 6-phosphofructokinase | 0.0105 | 0.1168 | 0.21 |
Mycobacterium ulcerans | thymidylate synthase | 0.0105 | 0.1161 | 0.2086 |
Loa Loa (eye worm) | RNA binding protein | 0.0072 | 0.0734 | 0.13 |
Echinococcus granulosus | O glycosyltransferase | 0.004 | 0.0316 | 0.0312 |
Brugia malayi | Amyloid A4 extracellular domain containing protein | 0.0334 | 0.415 | 0.7477 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0105 | 0.1168 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0083 | 0.0878 | 0.0875 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0301 | 0.0297 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0017 | 0.0014 | 0.001 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0042 | 0.0347 | 0.2946 |
Brugia malayi | beta-lactamase family protein | 0.0042 | 0.0347 | 0.0619 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0017 | 0.0014 | 0.001 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0116 | 0.1309 | 0.2354 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0347 | 0.0601 |
Loa Loa (eye worm) | beta-lactamase | 0.0042 | 0.0347 | 0.0601 |
Toxoplasma gondii | orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase | 0.0062 | 0.0607 | 0.1432 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0042 | 0.0347 | 0.0619 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0017 | 0.0014 | 0.001 |
Trichomonas vaginalis | 6-phosphofructokinase, putative | 0.0028 | 0.0168 | 0.1406 |
Brugia malayi | beta-lactamase | 0.0042 | 0.0347 | 0.0619 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0017 | 0.0014 | 0.001 |
Mycobacterium tuberculosis | Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) | 0.0105 | 0.1168 | 0.21 |
Mycobacterium ulcerans | orotidine 5'-phosphate decarboxylase | 0.0062 | 0.0607 | 0.1088 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0017 | 0.0014 | 0.001 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0046 | 0.0394 | 0.0925 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0057 | 0.0534 | 0.094 |
Schistosoma mansoni | adenoreceptor | 0.0017 | 0.0014 | 0.001 |
Toxoplasma gondii | phosphofructokinase domain-containing protein | 0.0028 | 0.0168 | 0.0388 |
Echinococcus granulosus | dihydrofolate reductase | 0.0442 | 0.5549 | 0.5547 |
Chlamydia trachomatis | dihydrofolate reductase | 0.0442 | 0.5549 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0042 | 0.0347 | 0.2946 |
Brugia malayi | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase | 0.004 | 0.0314 | 0.0559 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | g protein coupled receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | biogenic amine receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0017 | 0.0014 | 0.001 |
Entamoeba histolytica | hypothetical protein | 0.0083 | 0.0878 | 0.7104 |
Echinococcus multilocularis | g protein coupled receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0018 | 0.003 | 0.0027 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0105 | 0.1168 | 0.2085 |
Brugia malayi | sulfakinin receptor protein | 0.0017 | 0.0014 | 0.0018 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0017 | 0.0014 | 0.001 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.164 | 0.2938 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0017 | 0.0014 | 0.001 |
Mycobacterium ulcerans | beta-lactamase | 0.0042 | 0.0347 | 0.0619 |
Echinococcus multilocularis | neuropeptide receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0042 | 0.0347 | 0.0343 |
Echinococcus granulosus | 6 phosphofructokinase | 0.0105 | 0.1168 | 0.1165 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase, putative | 0.005 | 0.0446 | 0.1049 |
Echinococcus multilocularis | somatostatin receptor | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | glutathione reductase | 0.0046 | 0.0394 | 0.0703 |
Plasmodium falciparum | thioredoxin reductase | 0.0046 | 0.0394 | 0.0925 |
Schistosoma mansoni | opsin-like receptor | 0.0017 | 0.0014 | 0.001 |
Toxoplasma gondii | phosphofructokinase PFKII | 0.0028 | 0.0168 | 0.0388 |
Echinococcus granulosus | g-protein coupled receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | neuropeptide F receptor | 0.0017 | 0.0014 | 0.0018 |
Brugia malayi | Dopamine receptor protein 2 | 0.0017 | 0.0014 | 0.0018 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0042 | 0.0347 | 0.2946 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0028 | 0.0168 | 0.0295 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.003 | 0.0027 |
Brugia malayi | follicle stimulating hormone receptor | 0.0017 | 0.0014 | 0.0018 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0018 | 0.003 | 0.0027 |
Giardia lamblia | Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit | 0.0028 | 0.0168 | 0.5346 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0018 | 0.003 | 0.0048 |
Echinococcus granulosus | thymidylate synthase | 0.0105 | 0.1161 | 0.1157 |
Brugia malayi | TAR-binding protein | 0.0072 | 0.0734 | 0.1316 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0017 | 0.0014 | 0.001 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0534 | 0.094 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0042 | 0.0347 | 0.2946 |
Brugia malayi | Dopamine receptor protein 1 | 0.0017 | 0.0014 | 0.0018 |
Toxoplasma gondii | O-linked N-acetylglucosamine transferase | 0.0039 | 0.031 | 0.0727 |
Onchocerca volvulus | 0.0564 | 0.7138 | 1 | |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.0028 | 0.0168 | 0.0388 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0105 | 0.1168 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.003 | 0.0027 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0046 | 0.0394 | 0.0703 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0017 | 0.0014 | 0.0018 |
Loa Loa (eye worm) | TAR-binding protein | 0.0072 | 0.0734 | 0.13 |
Mycobacterium tuberculosis | Conserved protein | 0.0042 | 0.0347 | 0.0619 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0016 | 0.0004 | 0.0005 |
Echinococcus granulosus | g protein coupled receptor | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | putative neuropeptide receptor | 0.0017 | 0.0014 | 0.0018 |
Brugia malayi | hypothetical protein | 0.0083 | 0.0878 | 0.1577 |
Trypanosoma cruzi | orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative | 0.0062 | 0.0607 | 0.1432 |
Echinococcus granulosus | g protein coupled receptor | 0.0017 | 0.0014 | 0.001 |
Onchocerca volvulus | 0.0105 | 0.1161 | 0.1609 | |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0105 | 0.1168 | 0.1165 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0017 | 0.0014 | 0.0018 |
Plasmodium vivax | glutathione reductase, putative | 0.0046 | 0.0394 | 0.0925 |
Echinococcus granulosus | hypothetical protein | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0017 | 0.0014 | 0.001 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0042 | 0.0347 | 0.0619 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0347 | 0.0601 |
Brugia malayi | ORL1-like opioid receptor | 0.0017 | 0.0014 | 0.0018 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0017 | 0.0014 | 0.0018 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0017 | 0.0014 | 0.001 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0042 | 0.0347 | 0.0619 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0105 | 0.1158 | 0.2081 |
Brugia malayi | G protein-coupled receptor | 0.0017 | 0.0014 | 0.0018 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0028 | 0.0168 | 0.0295 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0014 | 0.0018 |
Trichomonas vaginalis | esterase, putative | 0.0042 | 0.0347 | 0.2946 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0016 | 0.0004 | 0.0005 |
Plasmodium falciparum | glutathione reductase | 0.0046 | 0.0394 | 0.0925 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0014 | 0.0018 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0018 | 0.003 | 0.0048 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | Serotonin receptor | 0.0017 | 0.0014 | 0.0018 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0105 | 0.1168 | 1 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0014 | 0.0018 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0028 | 0.0168 | 0.1406 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0042 | 0.0347 | 0.0619 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0046 | 0.0394 | 0.0686 |
Mycobacterium leprae | DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) | 0.0442 | 0.5549 | 1 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0042 | 0.0347 | 0.0619 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0105 | 0.1168 | 1 |
Schistosoma mansoni | amine GPCR | 0.0017 | 0.0014 | 0.001 |
Onchocerca volvulus | 0.0042 | 0.0347 | 0.0467 | |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | sex peptide receptor | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | beta-lactamase family protein | 0.0042 | 0.0347 | 0.0619 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0057 | 0.0534 | 0.0956 |
Onchocerca volvulus | 0.0042 | 0.0347 | 0.0467 | |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | fmrfamide receptor | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0014 | 0.0018 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0072 | 0.0734 | 0.1316 |
Schistosoma mansoni | amine GPCR | 0.0017 | 0.0014 | 0.001 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0105 | 0.1168 | 1 |
Echinococcus multilocularis | neuropeptide receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0017 | 0.0014 | 0.001 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0042 | 0.0347 | 0.0619 |
Echinococcus multilocularis | allatostatin A receptor | 0.0017 | 0.0014 | 0.001 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.034 | 0.4218 | 1 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0042 | 0.0347 | 0.0619 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0017 | 0.0014 | 0.001 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.034 | 0.4218 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0072 | 0.0734 | 0.073 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | fmrfamide receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0042 | 0.0347 | 0.0343 |
Schistosoma mansoni | opsin-like receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | orotidine 5'-phosphate decarboxylase | 0.0062 | 0.0607 | 0.0604 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | orotate phosphoribosyltransferase family protein | 0.0062 | 0.0607 | 0.1088 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Trypanosoma cruzi | orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative | 0.0062 | 0.0607 | 0.1432 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 0.0734 | 0.073 |
Mycobacterium tuberculosis | Hypothetical protein | 0.005 | 0.0446 | 0.0797 |
Brugia malayi | dihydrofolate reductase family protein | 0.0442 | 0.5549 | 1 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | amine GPCR | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0046 | 0.0394 | 0.039 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0017 | 0.0014 | 0.001 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0105 | 0.1158 | 0.2081 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0105 | 0.1158 | 0.1558 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0014 | 0.0018 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0017 | 0.0014 | 0.001 |
Trypanosoma brucei | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0105 | 0.1168 | 0.2763 |
Brugia malayi | Thioredoxin reductase | 0.0046 | 0.0394 | 0.0703 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.034 | 0.4218 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | neuropeptide receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | dihydrofolate reductase | 0.0442 | 0.5549 | 0.5547 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.034 | 0.4218 | 1 |
Schistosoma mansoni | biogenic amine receptor | 0.0017 | 0.0014 | 0.001 |
Mycobacterium ulcerans | dihydrofolate reductase DfrA | 0.0442 | 0.5549 | 1 |
Brugia malayi | Dihydrofolate reductase | 0.0442 | 0.5549 | 1 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0017 | 0.0014 | 0.001 |
Mycobacterium leprae | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) | 0.0105 | 0.1161 | 0.1564 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 0.0734 | 0.073 |
Brugia malayi | RNA binding protein | 0.0072 | 0.0734 | 0.1316 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0017 | 0.0014 | 0.001 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.0105 | 0.1161 | 0.2086 |
Leishmania major | trypanothione reductase | 0.0046 | 0.0394 | 0.0925 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0105 | 0.1158 | 0.2081 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 0.0734 | 0.073 |
Entamoeba histolytica | hypothetical protein | 0.0083 | 0.0878 | 0.7104 |
Leishmania major | ATP-dependent phosphofructokinase | 0.0105 | 0.1168 | 0.2763 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0028 | 0.0168 | 0.1406 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | G-protein coupled receptor | 0.0017 | 0.0014 | 0.0018 |
Brugia malayi | RE15519p | 0.0017 | 0.0014 | 0.0018 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0105 | 0.1168 | 0.1165 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0014 | 0.0018 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0083 | 0.0878 | 0.0875 |
Mycobacterium tuberculosis | Conserved protein | 0.0042 | 0.0347 | 0.0619 |
Brugia malayi | thymidylate synthase | 0.0105 | 0.1161 | 0.2086 |
Mycobacterium tuberculosis | Conserved protein | 0.0042 | 0.0347 | 0.0619 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.003 | 0.0027 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0018 | 0.003 | 0.0027 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.034 | 0.4218 | 1 |
Echinococcus granulosus | neuropeptide receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | serotonin receptor | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0017 | 0.0014 | 0.0018 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.003 | 0.0027 |
Schistosoma mansoni | biogenic amine receptor | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | G-protein coupled receptor | 0.0017 | 0.0014 | 0.0018 |
Brugia malayi | hypothetical protein | 0.005 | 0.0446 | 0.0797 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | hypothetical protein | 0.0083 | 0.0878 | 0.0875 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0039 | 0.0301 | 0.0536 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0347 | 0.0601 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.027 | 0.3309 | 0.5961 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Loa Loa (eye worm) | dihydrofolate reductase | 0.0442 | 0.5549 | 1 |
Mycobacterium tuberculosis | Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) | 0.0442 | 0.5549 | 1 |
Echinococcus granulosus | fmrfamide receptor | 0.0017 | 0.0014 | 0.001 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0028 | 0.0168 | 0.1406 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0017 | 0.0014 | 0.001 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.0028 | 0.0168 | 0.0388 |
Mycobacterium leprae | Probable orotidine 5'-phosphate decarboxylase PyrF (OMP decarboxylase) (OMPDCase) (OMPdecase) | 0.0062 | 0.0607 | 0.0501 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 0.0734 | 0.073 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0017 | 0.0014 | 0.001 |
Plasmodium vivax | orotidine 5'-phosphate decarboxylase, putative | 0.0062 | 0.0607 | 0.1432 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0017 | 0.0014 | 0.001 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0072 | 0.0734 | 0.13 |
Schistosoma mansoni | dihydrofolate reductase | 0.0442 | 0.5549 | 0.5547 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0301 | 0.0519 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0042 | 0.0347 | 0.0814 |
Echinococcus multilocularis | g protein coupled receptor | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0017 | 0.0014 | 0.0018 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | sex peptide receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | serotonin receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | neuropeptide receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | thymidylate synthase | 0.0105 | 0.1161 | 0.1157 |
Loa Loa (eye worm) | hypothetical protein | 0.0264 | 0.3227 | 0.5806 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | Dopamine receptor | 0.0017 | 0.0014 | 0.0018 |
Echinococcus multilocularis | serotonin receptor | 0.0017 | 0.0014 | 0.001 |
Entamoeba histolytica | hypothetical protein | 0.0083 | 0.0878 | 0.7104 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0014 | 0.001 |
Mycobacterium ulcerans | 6-phosphofructokinase | 0.0105 | 0.1168 | 0.21 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0017 | 0.0014 | 0.001 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0042 | 0.0347 | 0.0619 |
Leishmania major | hypothetical protein, conserved | 0.0042 | 0.0347 | 0.0814 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0116 | 0.1309 | 0.185 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0017 | 0.0014 | 0.001 |
Giardia lamblia | O-linked GlcNAc transferase | 0.0023 | 0.0097 | 0.3055 |
Echinococcus multilocularis | tar DNA binding protein | 0.0072 | 0.0734 | 0.073 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0057 | 0.0534 | 0.0956 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0017 | 0.0014 | 0.0018 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0042 | 0.0347 | 0.2946 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
PC50 (functional) | = 0.66 uM | Cytotoxicity against human PANC1 cells assessed as cell viability after 3 hrs by WST-8 cells | ChEMBL. | 23287053 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.