Detailed information for compound 1725467

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 399.482 | Formula: C26H25NO3
  • H donors: 1 H acceptors: 2 LogP: 4.78 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: OCCOC1[N+](=C(CC1(C)C)/C=C/c1ccc2c3c1ccc1c3c(cc2)ccc1)[O-]
  • InChi: 1S/C26H25NO3/c1-26(2)16-21(27(29)25(26)30-15-14-28)12-10-17-6-7-20-9-8-18-4-3-5-19-11-13-22(17)24(20)23(18)19/h3-13,25,28H,14-16H2,1-2H3/b12-10+
  • InChiKey: LMFOMMYDROZBAP-ZRDIBKRKSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0022 0.0332 0.0545
Leishmania major cathepsin L-like protease 0.0034 0.0606 0.1604
Brugia malayi beta-lactamase family protein 0.0036 0.0659 0.1061
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.0162 0.0162
Plasmodium falciparum cysteine proteinase falcipain 1 0.0017 0.0204 0.0965
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0606 0.0682
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0278 0.0278
Onchocerca volvulus 0.0022 0.0332 0.0815
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0022
Echinococcus multilocularis cysteine protease 0.0034 0.0606 0.0606
Plasmodium vivax JmjC domain containing protein 0.0016 0.0162 0.1811
Loa Loa (eye worm) hypothetical protein 0.0011 0.0052 0.0085
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0278 0.0278
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0256 0.6095 1
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0278 0.0264
Schistosoma mansoni jumonji domain containing protein 0.0058 0.1217 0.1205
Schistosoma mansoni thyroid hormone receptor 0.002 0.0278 0.0264
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0606 0.0682
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0606 0.0682
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0117 0.2659 0.905
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0256 0.6095 1
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.035 0.5
Echinococcus granulosus cathepsin L cysteine protease 0.0017 0.0204 0.0204
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.035 0.0412
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0496 0.0495
Trypanosoma cruzi DNA polymerase eta, putative 0.002 0.026 0.0724
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0496 0.0495
Onchocerca volvulus 0.0082 0.1812 0.4599
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.1138 0.8861
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.026 0.053
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.026 0.053
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0128 0.2933 1
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.2437 0.2426
Echinococcus granulosus cpg binding protein 0.0031 0.0537 0.0537
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.2437 0.379
Entamoeba histolytica cysteine proteinase, putative 0.0034 0.0606 0.1098
Trypanosoma cruzi cysteine proteinase, putative 0.0017 0.0204 0.053
Echinococcus multilocularis 6 phosphofructokinase 0.0108 0.2437 0.2437
Echinococcus multilocularis Nuclear hormone receptor HR96 0.001 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0011 0.0052 0.0085
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0659 0.2107
Echinococcus granulosus cathepsin L 0.0017 0.0204 0.0204
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0162 0.0265
Schistosoma mansoni cathepsin F (C01 family) 0.0022 0.0332 0.0319
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.1263 0.3975
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0022
Brugia malayi jmjC domain containing protein 0.0016 0.0162 0.0243
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.0332 0.0217
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.026 0.053
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.1263 0.1251
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0659 0.1061
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.0162 0.0162
Onchocerca volvulus 0.0027 0.0438 0.1084
Brugia malayi beta-lactamase 0.0036 0.0659 0.1061
Mycobacterium leprae Probable lipase LipE 0.0036 0.0659 0.1479
Onchocerca volvulus 0.0034 0.0606 0.1515
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0278 0.0456
Onchocerca volvulus 0.0036 0.0659 0.165
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0659 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0278 0.0434
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0034 0.0606 0.0606
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0278 0.0675
Brugia malayi jmjC domain containing protein 0.006 0.1258 0.2045
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0278 0.0264
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0496 0.0495
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.026 0.053
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.3923 0.6312
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0278 0.0434
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.2437 0.6103
Loa Loa (eye worm) phosphofructokinase 0.0108 0.2437 0.3998
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0017 0.0203 0.0203
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.001 0.0014 0.0014
Brugia malayi Cathepsin L-like precursor 0.0034 0.0606 0.0974
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0659 0.2107
Onchocerca volvulus 0.0034 0.0606 0.1515
Brugia malayi hypothetical protein 0.0011 0.0042 0.0046
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.1263 0.1263
Brugia malayi Cathepsin L-like precursor 0.0034 0.0606 0.0974
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0034 0.0606 1
Brugia malayi phosphofructokinase 0.0108 0.2437 0.3984
Echinococcus multilocularis geminin 0.0339 0.8158 0.8158
Loa Loa (eye worm) hypothetical protein 0.0016 0.0162 0.0265
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0017 0.0204 0.0333
Brugia malayi cathepsin F-like cysteine proteinase 0.0011 0.0052 0.0062
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.026 0.053
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0096 0.0096
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.026 0.053
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.026 0.0095
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0204 0.0314
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0278 0.0456
Loa Loa (eye worm) hypothetical protein 0.002 0.0278 0.0456
Trypanosoma cruzi cysteine peptidase, putative 0.0128 0.2933 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0042 0.0069
Loa Loa (eye worm) hypothetical protein 0.002 0.0278 0.0456
Trypanosoma cruzi major cysteine proteinase, putative 0.01 0.2258 0.7656
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0017 0.0204 0.0191
Leishmania major hypothetical protein, conserved 0.0036 0.0659 0.1794
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0228 0.5405 1
Echinococcus multilocularis cathepsin L cysteine protease 0.0034 0.0606 0.0606
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0659 0.0646
Loa Loa (eye worm) hypothetical protein 0.002 0.0278 0.0456
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.3923 0.6312
Schistosoma mansoni phd/f-box containing protein 0.0016 0.0162 0.0148
Loa Loa (eye worm) hypothetical protein 0.0011 0.0042 0.0069
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0659 0.0659
Loa Loa (eye worm) ctsf protein 0.0034 0.0606 0.0994
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0278 0.0278
Brugia malayi CXXC zinc finger family protein 0.0029 0.0496 0.0793
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0278 0.0434
Loa Loa (eye worm) hypothetical protein 0.0027 0.0438 0.0718
Echinococcus multilocularis cathepsin L 0.0017 0.0204 0.0204
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.035 0.4239
Loa Loa (eye worm) hypothetical protein 0.0034 0.0606 0.0994
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0278 0.0264
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0496 0.0495
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0278 0.0264
Loa Loa (eye worm) nuclear receptor NHR-67 0.001 0.0014 0.0022
Echinococcus granulosus dna polymerase eta 0.002 0.026 0.026
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0165 0.3862 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.026 0.0724
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0278 0.0434
Plasmodium vivax vivapain-2 0.0034 0.0606 0.9132
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0108 0.2437 1
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0496 0.3038
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0659 0.0771
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0278 0.0434
Loa Loa (eye worm) hypothetical protein 0.0016 0.0162 0.0265
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0659 0.1942
Loa Loa (eye worm) hypothetical protein 0.0012 0.0084 0.0138
Onchocerca volvulus 0.0034 0.0606 0.1515
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0606 0.0682
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0659 0.183
Loa Loa (eye worm) hypothetical protein 0.002 0.0278 0.0456
Brugia malayi ecdysteroid receptor 0.002 0.0278 0.0434
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0496 1
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0278 0.0434
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0278 0.0278
Schistosoma mansoni DNA polymerase eta 0.002 0.026 0.0247
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0011 0.0042 0.0028
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.026 0.0405
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0029 0.0496 0.0701
Loa Loa (eye worm) DR-78 0.001 0.0014 0.0022
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0659 0.1081
Loa Loa (eye worm) hypothetical protein 0.0022 0.0332 0.0545
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.026 0.0405
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.1263 0.4608
Trypanosoma brucei unspecified product 0.002 0.026 0.053
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0082 0.1812 0.2957
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.026 0.053
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.026 0.0247
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0022
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0496 0.3038
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0128 0.2933 1
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0659 0.0659
Echinococcus multilocularis dna polymerase eta 0.002 0.026 0.026
Plasmodium vivax vivapain-3 0.0017 0.0204 0.2517
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0278 0.0434
Brugia malayi beta-lactamase family protein 0.0036 0.0659 0.1061
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.026 0.053
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0496 0.0798
Leishmania major ATP-dependent phosphofructokinase 0.0108 0.2437 0.821
Loa Loa (eye worm) hypothetical protein 0.0036 0.0659 0.1081
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0022
Brugia malayi nuclear receptor RXR 0.0011 0.0042 0.0046
Loa Loa (eye worm) hypothetical protein 0.002 0.0278 0.0456
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.035 0.0848
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0278 0.0456
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0496 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0128 0.2933 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0606 0.0682
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0606 0.0682
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0128 0.2933 1
Leishmania major cysteine peptidase A (CPA) 0.0034 0.0606 0.1604
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0278 0.0434
Leishmania major cathepsin L-like protease 0.0034 0.0606 0.1604
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0606 0.0682
Loa Loa (eye worm) hypothetical protein 0.0011 0.0042 0.0069
Schistosoma mansoni intermediate filament proteins 0.0027 0.0438 0.0424
Loa Loa (eye worm) hypothetical protein 0.0026 0.0426 0.0698
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0278 0.0434
Onchocerca volvulus 0.0027 0.0438 0.1084
Schistosoma mansoni nuclear hormone receptor 0.002 0.0278 0.0264
Schistosoma mansoni jumonji/arid domain-containing protein 0.006 0.1258 0.1246
Schistosoma mansoni thyroid hormone receptor 0.002 0.0278 0.0264
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0496 0.7325
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.2437 0.6103
Loa Loa (eye worm) fibroinase 0.0034 0.0606 0.0994
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0606 0.0682
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0278 0.0264
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0278 0.0456
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0278 0.0278
Loa Loa (eye worm) hypothetical protein 0.0036 0.0659 0.1081
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0496 1
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0278 0.0264
Brugia malayi jmjC domain containing protein 0.0016 0.0162 0.0243
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0165 0.3862 1
Onchocerca volvulus 0.0034 0.0606 0.1515
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0278 0.0278
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0496 0.0495
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0606 0.0682
Brugia malayi 6-phosphofructokinase 0.0108 0.2437 0.3984
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.001 0.0014 0.0014
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.026 0.053
Brugia malayi 6-phosphofructokinase 0.0108 0.2437 0.3984
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0204 0.053
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0659 0.0646
Loa Loa (eye worm) hypothetical protein 0.0022 0.0332 0.0545
Entamoeba histolytica cysteine proteinase, putative 0.0034 0.0606 0.1098
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.035 0.171
Onchocerca volvulus Glucosylceramidase homolog 0.0168 0.3923 1
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.026 0.0095
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0128 0.2933 1
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.0162 0.0162
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.001 0.0014 0.0014
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0659 0.0774
Mycobacterium tuberculosis Conserved protein 0.0036 0.0659 0.0774
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.2437 0.379
Echinococcus granulosus lamin dm0 0.0027 0.0438 0.0438
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0278 0.0264
Loa Loa (eye worm) hypothetical protein 0.002 0.0278 0.0456
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0162 0.0381
Onchocerca volvulus Cathepsin L homolog 0.0034 0.0606 0.1515
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0278 0.0278
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.6095 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0128 0.2933 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0034 0.0606 0.0682
Trypanosoma cruzi cysteine peptidase, putative 0.0034 0.0606 0.1924
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.3923 0.6312
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.6095 1
Brugia malayi Cathepsin L-like precursor 0.0034 0.0606 0.0974
Echinococcus granulosus nuclear receptor nhr 48 0.001 0.0014 0.0014
Schistosoma mansoni lamin 0.0027 0.0438 0.0424
Echinococcus multilocularis phd:f box containing protein 0.0016 0.0162 0.0162
Brugia malayi cathepsin L-like precursor 0.0022 0.0332 0.0524
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0017 0.0203 0.0203
Onchocerca volvulus 0.002 0.0278 0.0675
Echinococcus granulosus 6 phosphofructokinase 0.0108 0.2437 0.2437
Brugia malayi hypothetical protein 0.0011 0.0042 0.0046
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.026 0.053
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.026 0.026
Leishmania major cathepsin L-like protease 0.0128 0.2933 1
Echinococcus granulosus dna polymerase kappa 0.002 0.026 0.026
Onchocerca volvulus 0.0036 0.0659 0.165
Schistosoma mansoni hypothetical protein 0.0339 0.8158 0.8155
Plasmodium falciparum cysteine proteinase falcipain 3 0.0034 0.0606 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0278 0.0434
Loa Loa (eye worm) hypothetical protein 0.002 0.0278 0.0456
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.1263 1
Schistosoma mansoni cpg binding protein 0.0029 0.0496 0.0483
Plasmodium vivax unspecified product 0.0017 0.0204 0.2517
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0204 0.0314
Echinococcus granulosus intermediate filament protein 0.0027 0.0438 0.0438
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0058 0.1217 0.1217
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.2437 0.2426
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0128 0.2933 1
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0278 0.0434
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.1263 0.1251
Echinococcus granulosus lamin 0.0027 0.0438 0.0438
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0022
Echinococcus multilocularis lamin 0.0027 0.0438 0.0438
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0162 0.0381
Echinococcus multilocularis cysteine protease 0.0034 0.0606 0.0606
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0014 0.0014
Schistosoma mansoni cathepsin F (C01 family) 0.0034 0.0606 0.0593
Trypanosoma cruzi cysteine proteinase, putative 0.0017 0.0204 0.053
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0659 0.0774
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.1258 0.2063
Echinococcus multilocularis Nuclear hormone receptor HR96 0.001 0.0014 0.0014
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0278 0.0434
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0278 0.0675
Brugia malayi jmjC domain containing protein 0.0058 0.1217 0.1978
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0014 0.0014
Plasmodium vivax vivapain-2 0.0034 0.0606 0.9132
Plasmodium vivax vivapain-1 0.0017 0.0204 0.2517
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0022
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0128 0.2933 1
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0659 0.0774
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0496 0.7531
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0128 0.2933 1
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.026 0.0356
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.2437 0.8279
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0278 0.0456
Echinococcus granulosus cathepsin l1 0.0034 0.0606 0.0606
Echinococcus granulosus Nuclear hormone receptor HR96 0.001 0.0014 0.0014
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.0162 0.0148
Schistosoma mansoni cathepsin s 0.0011 0.0052 0.0038
Brugia malayi Cathepsin L-like precursor 0.0022 0.0332 0.0524
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.026 0.0724
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0606 0.0682
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0042 0.0046
Brugia malayi intermediate filament protein 0.0027 0.0438 0.0697
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.026 0.0724
Mycobacterium tuberculosis Conserved protein 0.0036 0.0659 0.0774
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0022
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.13 0.1288
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0606 0.0682
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.035 0.0174
Brugia malayi jmjC domain containing protein 0.0016 0.0162 0.0243
Loa Loa (eye worm) nuclear hormone receptor 0.001 0.0014 0.0022
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.1263 0.4608
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0017 0.0204 0.0191
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0606 0.0682
Leishmania major cathepsin L-like protease 0.0034 0.0606 0.1604
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0278 0.0278
Loa Loa (eye worm) hypothetical protein 0.0012 0.0084 0.0138
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0659 0.0774
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0034 0.0606 0.0994
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.4146 0.6691
Mycobacterium tuberculosis Conserved protein 0.0036 0.0659 0.0774
Leishmania major DNA polymerase kappa, putative 0.002 0.026 0.0356
Loa Loa (eye worm) hypothetical protein 0.0011 0.0052 0.0085
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0659 0.0771
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0496 0.3038
Brugia malayi nuclear hormone receptor 0.002 0.0278 0.0434
Schistosoma mansoni cathepsin F (C01 family) 0.0034 0.0606 0.0593
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.2437 0.379
Brugia malayi Cathepsin L-like precursor 0.0022 0.0332 0.0524
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0606 0.0682
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.026 0.0724
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0034 0.0606 1
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0016 0.0162 0.0181
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0011 0.0042 0.0042
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.6095 1
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.3923 0.6312
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0278 0.0278
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.035 0.068
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0022
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0011 0.0042 0.0069
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.2437 0.8243
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0022
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0606 0.0682
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.6095 1
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0082 0.1812 0.18
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0278 0.0278
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0108 0.2437 0.4231
Onchocerca volvulus Cathepsin F homolog 0.0034 0.0606 0.1515
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0017 0.0204 0.0333
Entamoeba histolytica deoxycytidyl transferase, putative 0.002 0.026 0.0152
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0034 0.0606 0.0682
Echinococcus multilocularis nuclear receptor nhr 48 0.001 0.0014 0.0014
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.1263 0.195
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0496 0.0495
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0278 0.0434
Loa Loa (eye worm) hypothetical protein 0.0036 0.0659 0.1081
Mycobacterium ulcerans 6-phosphofructokinase 0.0108 0.2437 1
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0438 0.0718
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.026 0.0247
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0011 0.0052 0.0062
Brugia malayi Papain family cysteine protease containing protein 0.0034 0.0606 0.0974
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0606 0.0682
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.2437 0.379
Brugia malayi nuclear receptor NHR-88 0.002 0.0278 0.0434
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0278 0.0264
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.035 0.4914
Loa Loa (eye worm) hypothetical protein 0.0165 0.3862 0.6336
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0278 0.0434
Entamoeba histolytica cysteine protease, putative 0.0034 0.0606 0.1098
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.026 0.053
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.2437 0.6103
Loa Loa (eye worm) hypothetical protein 0.002 0.0278 0.0456
Echinococcus granulosus L aminoadipate semialdehyde 0.0082 0.1812 0.1812
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0278 0.0278
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0659 0.0771
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0022
Schistosoma mansoni jumonji domain containing protein 0.0016 0.0162 0.0148
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.0162 0.0148
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.026 0.053
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0606 0.0682
Loa Loa (eye worm) hypothetical protein 0.0036 0.0659 0.1081
Echinococcus multilocularis lamin dm0 0.0027 0.0438 0.0438
Schistosoma mansoni protein phosphatase 2C 0.0016 0.0162 0.0148
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0606 0.0682
Trypanosoma cruzi cysteine peptidase, putative 0.0128 0.2933 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0011 0.0052 0.0085
Mycobacterium ulcerans lipase LipD 0.0036 0.0659 0.183
Onchocerca volvulus 0.0034 0.0606 0.1515
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0131 0.0193
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0278 0.0278
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0438 0.0697
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0128 0.2933 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0034 0.0606 0.0606
Brugia malayi Cathepsin L-like precursor 0.0011 0.0052 0.0062
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0042 0.0046
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0278 0.0456
Loa Loa (eye worm) nuclear receptor nhr-7B 0.001 0.0014 0.0022
Schistosoma mansoni lamin 0.0027 0.0438 0.0424
Schistosoma mansoni cpg binding protein 0.0031 0.0537 0.0524
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.3923 0.6312
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0278 0.0456
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0496 0.0813
Mycobacterium ulcerans beta-lactamase 0.0036 0.0659 0.183
Echinococcus multilocularis musashi 0.0027 0.0438 0.0438
Echinococcus multilocularis cathepsin L cysteine protease 0.0034 0.0606 0.0606
Schistosoma mansoni hypothetical protein 0.0339 0.8158 0.8155
Onchocerca volvulus 0.0029 0.0496 0.1233
Echinococcus multilocularis dna polymerase kappa 0.002 0.026 0.026
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0017 0.0204 0.0191
Leishmania major DNA polymerase eta, putative 0.002 0.026 0.0356
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0022
Loa Loa (eye worm) beta-lactamase 0.0036 0.0659 0.1081
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0496 0.7531
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0162 0.0265
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0278 0.0456
Brugia malayi Cathepsin L-like precursor 0.0034 0.0606 0.0974
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0278 0.0278
Loa Loa (eye worm) hypothetical protein 0.0036 0.0659 0.1081
Onchocerca volvulus 0.0036 0.0659 0.165
Echinococcus granulosus cathepsin l1 0.0022 0.0332 0.0332
Loa Loa (eye worm) hypothetical protein 0.0013 0.0096 0.0158
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0278 0.0434
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.0332 0.0217
Onchocerca volvulus 0.0034 0.0606 0.1515
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0496 0.7325
Loa Loa (eye worm) hypothetical protein 0.002 0.026 0.0427
Echinococcus granulosus cysteine protease 0.0017 0.0204 0.0204
Loa Loa (eye worm) hypothetical protein 0.0011 0.0042 0.0069
Loa Loa (eye worm) hypothetical protein 0.0016 0.0162 0.0265
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0278 0.0278
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.3923 0.6312
Leishmania major cathepsin L-like protease 0.0034 0.0606 0.1604
Toxoplasma gondii ABC1 family protein 0.0036 0.0659 0.4512
Echinococcus granulosus Nuclear hormone receptor HR96 0.001 0.0014 0.0014
Mycobacterium ulcerans hypothetical protein 0.0036 0.0659 0.183
Loa Loa (eye worm) hypothetical protein 0.0011 0.0042 0.0069
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.0162 0.0162
Trypanosoma cruzi cysteine peptidase, putative 0.0128 0.2933 1
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0659 0.0771
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0438 0.0718
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0162 0.0265
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0606 0.0682
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0606 0.0682
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.0162 0.0162
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0131 0.0215
Entamoeba histolytica cysteine proteinase, putative 0.0022 0.0332 0.0349
Echinococcus granulosus phd:f box containing protein 0.0016 0.0162 0.0162
Echinococcus granulosus lysine specific demethylase 5A 0.006 0.1258 0.1258
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0659 0.183
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0058 0.1217 0.1217
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.026 0.0427
Trichomonas vaginalis esterase, putative 0.0036 0.0659 0.0771
Toxoplasma gondii cathepsin CPL 0.0034 0.0606 0.4034
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.6095 1
Echinococcus multilocularis L aminoadipate semialdehyde 0.0082 0.1812 0.1812
Schistosoma mansoni cpg binding protein 0.0031 0.0537 0.0524
Brugia malayi Cathepsin L-like precursor 0.0034 0.0606 0.0974
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.2437 0.3998
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.4146 0.6691
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0278 0.0278
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.026 0.053
Echinococcus granulosus FTZ F1 alpha 0.002 0.0278 0.0278
Leishmania major cathepsin L-like protease 0.0034 0.0606 0.1604
Onchocerca volvulus 0.0034 0.0606 0.1515
Loa Loa (eye worm) hypothetical protein 0.0082 0.1812 0.2972
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0606 0.0682
Brugia malayi jmjC domain containing protein 0.0016 0.0162 0.0243
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.6095 1
Leishmania major cathepsin L-like protease 0.0128 0.2933 1
Trypanosoma cruzi cysteine protease, putative 0.0017 0.0204 0.053
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.3923 0.6312
Echinococcus granulosus cathepsin l cysteine peptidase 0.0034 0.0606 0.0606
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0022
Echinococcus multilocularis cpg binding protein 0.0031 0.0537 0.0537
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0278 0.0278
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0042 0.0028
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.0606 0.0682
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0022
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.026 0.053
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0011 0.0042 0.0042
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.2437 0.3998
Echinococcus granulosus cathepsin L cysteine proteinase 0.0034 0.0606 0.0606
Echinococcus granulosus geminin 0.0339 0.8158 0.8158
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0659 0.0774
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0606 0.0682
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0278 0.0278
Echinococcus granulosus thyroid hormone receptor alpha 0.001 0.0014 0.0014
Schistosoma mansoni coup transcription factor 0.002 0.0278 0.0264
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0096 0.0096
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.0162 0.0162
Echinococcus multilocularis lysine specific demethylase 5A 0.0058 0.1217 0.1217
Brugia malayi Cathepsin L-like cysteine proteinase 0.0022 0.0332 0.0524
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0034 0.0606 0.0994
Loa Loa (eye worm) cysteine protease 0.0034 0.0606 0.0994
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0606 0.0682
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.026 0.026
Brugia malayi Cathepsin L-like precursor 0.0034 0.0606 0.0974
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0278 0.0675
Leishmania major cathepsin L-like protease 0.0128 0.2933 1
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0278 0.0434
Loa Loa (eye worm) hypothetical protein 0.0036 0.0659 0.1081
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0659 0.0771
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0659 0.0774
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.035 0.0412
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.1263 0.4608
Entamoeba histolytica hypothetical protein 0.0023 0.035 0.0398
Schistosoma mansoni jumonji/arid domain-containing protein 0.006 0.1258 0.1246
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0108 0.2437 1
Brugia malayi steroid hormone receptor 0.002 0.0278 0.0434
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.1263 0.1263
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0278 0.0264
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.035 0.171
Trypanosoma cruzi cruzipain precursor, putative 0.0128 0.2933 1
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0659 0.0774
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0128 0.2933 1
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0017 0.0204 0.053
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0496 0.0495
Onchocerca volvulus Cathepsin L homolog 0.0034 0.0606 0.1515
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0659 0.1479

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 11.1 uM Antiproliferative activity against human BJ cells ChEMBL. 23352483
IC50 (functional) > 25 uM Antiproliferative activity against human HCT116 cells ChEMBL. 23352483

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 23352483

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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