Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0028 | 0.0168 | 0.1434 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0017 | 0.0014 | 0.001 |
Trichomonas vaginalis | 6-phosphofructokinase, putative | 0.0028 | 0.0168 | 0.1406 |
Brugia malayi | phosphofructokinase | 0.0105 | 0.1168 | 0.21 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | orexin receptor type 2 | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | beta-lactamase | 0.0042 | 0.0347 | 0.0619 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0017 | 0.0014 | 0.001 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0347 | 0.0601 |
Brugia malayi | putative neuropeptide receptor | 0.0017 | 0.0014 | 0.0018 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 0.0734 | 0.073 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0016 | 0.0004 | 0.0005 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0018 | 0.003 | 0.0027 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0105 | 0.1168 | 1 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0028 | 0.0168 | 0.1406 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0116 | 0.1309 | 0.2354 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Trypanosoma brucei | orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative | 0.0062 | 0.0607 | 0.1432 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0017 | 0.0014 | 0.0018 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | uridine 5' monophosphate synthase | 0.0062 | 0.0607 | 0.0604 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0105 | 0.1168 | 1 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0042 | 0.0347 | 0.0619 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0017 | 0.0014 | 0.001 |
Entamoeba histolytica | hypothetical protein | 0.0083 | 0.0878 | 0.7104 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0016 | 0.0004 | 0.0005 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0105 | 0.1158 | 0.1558 |
Brugia malayi | Serotonin receptor | 0.0017 | 0.0014 | 0.0018 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.034 | 0.4218 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0042 | 0.0347 | 0.0814 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0017 | 0.0014 | 0.001 |
Loa Loa (eye worm) | phosphofructokinase | 0.0105 | 0.1168 | 0.2085 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0046 | 0.0394 | 0.0686 |
Mycobacterium ulcerans | lipase LipD | 0.0042 | 0.0347 | 0.0619 |
Brugia malayi | dihydrofolate reductase family protein | 0.0442 | 0.5549 | 1 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.034 | 0.4218 | 1 |
Brugia malayi | thymidylate synthase | 0.0105 | 0.1161 | 0.2086 |
Toxoplasma gondii | phosphofructokinase domain-containing protein | 0.0028 | 0.0168 | 0.0388 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0042 | 0.0347 | 0.2946 |
Echinococcus multilocularis | dihydrofolate reductase | 0.0442 | 0.5549 | 0.5547 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0018 | 0.003 | 0.0027 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0014 | 0.0018 |
Echinococcus granulosus | serotonin receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.003 | 0.0027 |
Leishmania major | hypothetical protein, conserved | 0.0042 | 0.0347 | 0.0814 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0347 | 0.0601 |
Schistosoma mansoni | neuropeptide receptor | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0018 | 0.003 | 0.0048 |
Echinococcus multilocularis | 6 phosphofructokinase | 0.0105 | 0.1168 | 0.1165 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0017 | 0.0014 | 0.0018 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0028 | 0.0168 | 0.1406 |
Leishmania major | trypanothione reductase | 0.0046 | 0.0394 | 0.0925 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0042 | 0.0347 | 0.0619 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0017 | 0.0014 | 0.0018 |
Echinococcus granulosus | allatostatin A receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | G-protein coupled receptor | 0.0017 | 0.0014 | 0.0018 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0083 | 0.0878 | 0.0875 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 0.0734 | 0.073 |
Trypanosoma cruzi | orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative | 0.0062 | 0.0607 | 0.1432 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0014 | 0.001 |
Toxoplasma gondii | thioredoxin reductase | 0.0046 | 0.0394 | 0.0925 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0014 | 0.0018 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | g protein coupled receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0017 | 0.0014 | 0.001 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0105 | 0.1168 | 1 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0105 | 0.1158 | 0.2081 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0017 | 0.0014 | 0.001 |
Trypanosoma brucei | trypanothione reductase | 0.0046 | 0.0394 | 0.0925 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0014 | 0.0018 |
Schistosoma mansoni | histamine h1 receptor | 0.0017 | 0.0014 | 0.001 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase, putative | 0.005 | 0.0446 | 0.1049 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | sulfakinin receptor protein | 0.0017 | 0.0014 | 0.0018 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | Melatonin receptor type 1A | 0.0017 | 0.0014 | 0.0018 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0042 | 0.0347 | 0.0619 |
Echinococcus multilocularis | thymidylate synthase | 0.0105 | 0.1161 | 0.1157 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0039 | 0.0301 | 0.0536 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0017 | 0.0014 | 0.001 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.034 | 0.4218 | 1 |
Brugia malayi | RE15519p | 0.0017 | 0.0014 | 0.0018 |
Echinococcus granulosus | somatostatin receptor | 0.0017 | 0.0014 | 0.001 |
Loa Loa (eye worm) | TAR-binding protein | 0.0072 | 0.0734 | 0.13 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0105 | 0.1168 | 1 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | thymidylate synthase | 0.0105 | 0.1161 | 0.1157 |
Giardia lamblia | Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit | 0.0028 | 0.0168 | 0.5346 |
Giardia lamblia | O-linked GlcNAc transferase | 0.0023 | 0.0097 | 0.3055 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0042 | 0.0347 | 0.0619 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0105 | 0.1168 | 0.2085 |
Onchocerca volvulus | 0.0564 | 0.7138 | 1 | |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0017 | 0.0014 | 0.001 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0717 | 0.1271 |
Echinococcus granulosus | GPCR family 2 | 0.0018 | 0.003 | 0.0027 |
Echinococcus granulosus | neuropeptide receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | g protein coupled receptor | 0.0017 | 0.0014 | 0.001 |
Mycobacterium leprae | PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) | 0.0105 | 0.1168 | 0.1579 |
Entamoeba histolytica | hypothetical protein | 0.0083 | 0.0878 | 0.7104 |
Brugia malayi | Dopamine receptor | 0.0017 | 0.0014 | 0.0018 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0014 | 0.0018 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.164 | 0.2938 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0017 | 0.0014 | 0.001 |
Plasmodium vivax | glutathione reductase, putative | 0.0046 | 0.0394 | 0.0925 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0534 | 0.094 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.034 | 0.4218 | 1 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.0028 | 0.0168 | 0.0388 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0347 | 0.0601 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0017 | 0.0014 | 0.001 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0042 | 0.0347 | 0.2946 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0014 | 0.0018 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0017 | 0.0014 | 0.001 |
Treponema pallidum | NADH oxidase | 0.0016 | 0.0004 | 0.0033 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.003 | 0.0027 |
Brugia malayi | neuropeptide F receptor | 0.0017 | 0.0014 | 0.0018 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | amine GPCR | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0017 | 0.0014 | 0.001 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0116 | 0.1309 | 0.185 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0014 | 0.0018 |
Toxoplasma gondii | O-linked N-acetylglucosamine transferase | 0.0039 | 0.031 | 0.0727 |
Schistosoma mansoni | biogenic amine receptor | 0.0017 | 0.0014 | 0.001 |
Onchocerca volvulus | 0.0042 | 0.0347 | 0.0467 | |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0017 | 0.0014 | 0.001 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0028 | 0.0168 | 0.1406 |
Trypanosoma cruzi | orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative | 0.0062 | 0.0607 | 0.1432 |
Mycobacterium leprae | DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) | 0.0442 | 0.5549 | 1 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0042 | 0.0347 | 0.0343 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0042 | 0.0347 | 0.0619 |
Brugia malayi | larval opioid receptor | 0.0017 | 0.0014 | 0.0018 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0028 | 0.0168 | 0.0295 |
Brugia malayi | G-protein coupled receptor | 0.0017 | 0.0014 | 0.0018 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0017 | 0.0014 | 0.001 |
Mycobacterium ulcerans | dihydrofolate reductase DfrA | 0.0442 | 0.5549 | 1 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0105 | 0.1168 | 1 |
Leishmania major | orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative,OMPDCase-OPRTase, putative | 0.0062 | 0.0607 | 0.1432 |
Brugia malayi | hypothetical protein | 0.0083 | 0.0878 | 0.1577 |
Trypanosoma cruzi | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0105 | 0.1168 | 0.2763 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0017 | 0.0014 | 0.001 |
Trypanosoma brucei | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0105 | 0.1168 | 0.2763 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | amine GPCR | 0.0017 | 0.0014 | 0.001 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0105 | 0.1168 | 1 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0105 | 0.1168 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0042 | 0.0347 | 0.2946 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0046 | 0.0394 | 0.0925 |
Schistosoma mansoni | neuropeptide receptor | 0.0017 | 0.0014 | 0.001 |
Loa Loa (eye worm) | RNA binding protein | 0.0072 | 0.0734 | 0.13 |
Trichomonas vaginalis | conserved hypothetical protein | 0.005 | 0.0446 | 0.3796 |
Echinococcus multilocularis | allatostatin A receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | amine GPCR | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0072 | 0.0734 | 0.1316 |
Echinococcus granulosus | hypothetical protein | 0.0017 | 0.0014 | 0.001 |
Plasmodium falciparum | thioredoxin reductase | 0.0046 | 0.0394 | 0.0925 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.003 | 0.0027 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | orotate phosphoribosyltransferase family protein | 0.0062 | 0.0607 | 0.1088 |
Onchocerca volvulus | 0.0042 | 0.0347 | 0.0467 | |
Brugia malayi | Dopamine receptor protein 1 | 0.0017 | 0.0014 | 0.0018 |
Plasmodium vivax | orotidine 5'-phosphate decarboxylase, putative | 0.0062 | 0.0607 | 0.1432 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0017 | 0.0014 | 0.001 |
Trichomonas vaginalis | esterase, putative | 0.0042 | 0.0347 | 0.2946 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0042 | 0.0347 | 0.0814 |
Echinococcus multilocularis | g protein coupled receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | uridine 5' monophosphate synthase | 0.0062 | 0.0607 | 0.0604 |
Toxoplasma gondii | orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase | 0.0062 | 0.0607 | 0.1432 |
Mycobacterium tuberculosis | Hypothetical protein | 0.005 | 0.0446 | 0.0797 |
Brugia malayi | G protein-coupled receptor | 0.0017 | 0.0014 | 0.0018 |
Schistosoma mansoni | biogenic amine receptor | 0.0017 | 0.0014 | 0.001 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.034 | 0.4218 | 1 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0017 | 0.0014 | 0.0018 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0028 | 0.0168 | 0.1406 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0017 | 0.0014 | 0.0018 |
Echinococcus granulosus | sex peptide receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | serotonin receptor | 0.0017 | 0.0014 | 0.001 |
Chlamydia trachomatis | dihydrofolate reductase | 0.0442 | 0.5549 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0083 | 0.0878 | 0.0875 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0028 | 0.0168 | 0.0295 |
Mycobacterium ulcerans | beta-lactamase | 0.0042 | 0.0347 | 0.0619 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0105 | 0.1158 | 0.2081 |
Toxoplasma gondii | 6-phosphofructokinase | 0.0028 | 0.0168 | 0.0388 |
Mycobacterium tuberculosis | Conserved protein | 0.0042 | 0.0347 | 0.0619 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | alzheimer's disease beta-amyloid related | 0.0122 | 0.1384 | 0.1381 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0017 | 0.0014 | 0.001 |
Toxoplasma gondii | ABC1 family protein | 0.0042 | 0.0347 | 0.0814 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0028 | 0.0168 | 0.1406 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0083 | 0.0878 | 0.0875 |
Mycobacterium leprae | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) | 0.0105 | 0.1161 | 0.1564 |
Schistosoma mansoni | dihydrofolate reductase | 0.0442 | 0.5549 | 0.5547 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0014 | 0.001 |
Mycobacterium ulcerans | orotidine 5'-phosphate decarboxylase | 0.0062 | 0.0607 | 0.1088 |
Loa Loa (eye worm) | UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltransferase | 0.004 | 0.0314 | 0.0542 |
Entamoeba histolytica | hypothetical protein | 0.0083 | 0.0878 | 0.7104 |
Schistosoma mansoni | opsin-like receptor | 0.0017 | 0.0014 | 0.001 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0042 | 0.0347 | 0.0619 |
Brugia malayi | neuropeptide F receptor | 0.0017 | 0.0014 | 0.0018 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0347 | 0.0601 |
Brugia malayi | Dihydrofolate reductase | 0.0442 | 0.5549 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0042 | 0.0347 | 0.0619 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.0028 | 0.0168 | 0.0388 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0017 | 0.0014 | 0.001 |
Mycobacterium tuberculosis | Conserved protein | 0.0042 | 0.0347 | 0.0619 |
Schistosoma mansoni | o-linked n-acetylglucosamine transferase ogt | 0.004 | 0.0316 | 0.0312 |
Echinococcus multilocularis | O glycosyltransferase | 0.004 | 0.0316 | 0.0312 |
Echinococcus granulosus | g-protein coupled receptor | 0.0017 | 0.0014 | 0.001 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0046 | 0.0394 | 0.0703 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | tar DNA binding protein | 0.0072 | 0.0734 | 0.073 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0105 | 0.1168 | 0.2085 |
Schistosoma mansoni | neuropeptide receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | tar DNA binding protein | 0.0072 | 0.0734 | 0.073 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0017 | 0.0014 | 0.001 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.0105 | 0.1161 | 0.2086 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0017 | 0.0014 | 0.0018 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0042 | 0.0347 | 0.0601 |
Brugia malayi | glutathione reductase | 0.0046 | 0.0394 | 0.0703 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0105 | 0.1161 | 0.1157 |
Brugia malayi | 6-phosphofructokinase | 0.0105 | 0.1168 | 0.21 |
Plasmodium falciparum | glutathione reductase | 0.0046 | 0.0394 | 0.0925 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0057 | 0.0534 | 0.094 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | fmrfamide receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 0.0734 | 0.073 |
Schistosoma mansoni | opsin-like receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0042 | 0.0347 | 0.0343 |
Schistosoma mansoni | biogenic amine receptor | 0.0017 | 0.0014 | 0.001 |
Leishmania major | ATP-dependent phosphofructokinase | 0.0105 | 0.1168 | 0.2763 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0017 | 0.0014 | 0.001 |
Entamoeba histolytica | hypothetical protein | 0.0083 | 0.0878 | 0.7104 |
Brugia malayi | hypothetical protein | 0.005 | 0.0446 | 0.0797 |
Echinococcus multilocularis | somatostatin receptor | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | beta-lactamase family protein | 0.0042 | 0.0347 | 0.0619 |
Brugia malayi | follicle stimulating hormone receptor | 0.0017 | 0.0014 | 0.0018 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0046 | 0.0394 | 0.0925 |
Brugia malayi | 6-phosphofructokinase | 0.0105 | 0.1168 | 0.21 |
Mycobacterium tuberculosis | Conserved protein | 0.0042 | 0.0347 | 0.0619 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0014 | 0.0018 |
Echinococcus multilocularis | neuropeptide receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | fmrfamide receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | O glycosyltransferase | 0.004 | 0.0316 | 0.0312 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0017 | 0.0014 | 0.001 |
Giardia lamblia | O-linked GlcNAc transferase | 0.0039 | 0.031 | 1 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0116 | 0.1309 | 0.2354 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0017 | 0.0014 | 0.0018 |
Brugia malayi | Dopamine receptor protein 2 | 0.0017 | 0.0014 | 0.0018 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0017 | 0.0014 | 0.001 |
Toxoplasma gondii | phosphofructokinase PFKII | 0.0028 | 0.0168 | 0.0388 |
Echinococcus multilocularis | g protein coupled receptor | 0.0017 | 0.0014 | 0.001 |
Loa Loa (eye worm) | glutathione reductase | 0.0046 | 0.0394 | 0.0686 |
Wolbachia endosymbiont of Brugia malayi | orotidine-5'-phosphate decarboxylase | 0.0626 | 0.7948 | 1 |
Schistosoma mansoni | adenoreceptor | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | Amyloid A4 extracellular domain containing protein | 0.0334 | 0.415 | 0.7477 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | AKH receptor | 0.0017 | 0.0014 | 0.0018 |
Brugia malayi | ORL1-like opioid receptor | 0.0017 | 0.0014 | 0.0018 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0057 | 0.0534 | 0.0956 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.0028 | 0.0168 | 0.0388 |
Mycobacterium ulcerans | hypothetical protein | 0.0042 | 0.0347 | 0.0619 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0017 | 0.0014 | 0.001 |
Onchocerca volvulus | 0.0042 | 0.0347 | 0.0467 | |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | fmrfamide receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0018 | 0.003 | 0.0027 |
Schistosoma mansoni | amine GPCR | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0046 | 0.0394 | 0.039 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0057 | 0.0534 | 0.0956 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0105 | 0.1158 | 0.2081 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0042 | 0.0347 | 0.0814 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.027 | 0.3309 | 0.5961 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0028 | 0.0168 | 0.1406 |
Echinococcus granulosus | g protein coupled receptor | 0.0017 | 0.0014 | 0.001 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0042 | 0.0347 | 0.2946 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.003 | 0.0027 |
Mycobacterium leprae | Probable orotidine 5'-phosphate decarboxylase PyrF (OMP decarboxylase) (OMPDCase) (OMPdecase) | 0.0062 | 0.0607 | 0.0501 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0017 | 0.0014 | 0.001 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0347 | 0.0601 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0017 | 0.0014 | 0.001 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.034 | 0.4218 | 1 |
Schistosoma mansoni | orotidine 5'-phosphate decarboxylase | 0.0062 | 0.0607 | 0.0604 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0301 | 0.0297 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0347 | 0.0601 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0018 | 0.003 | 0.0027 |
Mycobacterium tuberculosis | Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) | 0.0105 | 0.1168 | 0.21 |
Loa Loa (eye worm) | beta-lactamase | 0.0042 | 0.0347 | 0.0601 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0042 | 0.0347 | 0.0619 |
Schistosoma mansoni | neuropeptide receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0105 | 0.1168 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0264 | 0.3227 | 0.5806 |
Loa Loa (eye worm) | dihydrofolate reductase | 0.0442 | 0.5549 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | neuropeptide receptor | 0.0017 | 0.0014 | 0.001 |
Mycobacterium ulcerans | thymidylate synthase | 0.0105 | 0.1161 | 0.2086 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0018 | 0.003 | 0.0048 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0301 | 0.0519 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0083 | 0.0878 | 0.0875 |
Mycobacterium tuberculosis | Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) | 0.0442 | 0.5549 | 1 |
Brugia malayi | TAR-binding protein | 0.0072 | 0.0734 | 0.1316 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0017 | 0.0014 | 0.001 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0042 | 0.0347 | 0.2946 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0105 | 0.1158 | 0.2081 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.003 | 0.003 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0017 | 0.0014 | 0.001 |
Mycobacterium tuberculosis | Probable reductase | 0.0105 | 0.1158 | 0.2081 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0046 | 0.0394 | 0.039 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0018 | 0.003 | 0.003 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0017 | 0.0014 | 0.001 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0042 | 0.0347 | 0.0619 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0116 | 0.1309 | 0.2354 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0014 | 0.0018 |
Brugia malayi | Thioredoxin reductase | 0.0046 | 0.0394 | 0.0703 |
Echinococcus granulosus | neuropeptide s receptor | 0.0017 | 0.0014 | 0.001 |
Mycobacterium ulcerans | 6-phosphofructokinase | 0.0105 | 0.1168 | 0.21 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0014 | 0.0018 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0105 | 0.1158 | 0.2081 |
Echinococcus multilocularis | GPCR, family 2 | 0.0018 | 0.003 | 0.0027 |
Echinococcus granulosus | dihydrofolate reductase | 0.0442 | 0.5549 | 0.5547 |
Echinococcus multilocularis | sex peptide receptor | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0017 | 0.0014 | 0.0018 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 0.0734 | 0.073 |
Schistosoma mansoni | opsin-like receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 0.0734 | 0.073 |
Plasmodium falciparum | orotidine 5'-phosphate decarboxylase | 0.0062 | 0.0607 | 0.1432 |
Echinococcus multilocularis | neuropeptide receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | amine GPCR | 0.0017 | 0.0014 | 0.001 |
Onchocerca volvulus | 0.0105 | 0.1161 | 0.1609 | |
Loa Loa (eye worm) | thymidylate synthase | 0.0105 | 0.1161 | 0.2071 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0042 | 0.0347 | 0.0343 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0014 | 0.0018 |
Brugia malayi | RNA binding protein | 0.0072 | 0.0734 | 0.1316 |
Trypanosoma cruzi | orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative | 0.0062 | 0.0607 | 0.1432 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.0028 | 0.0168 | 0.0388 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | serotonin receptor | 0.0017 | 0.0014 | 0.001 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0042 | 0.0347 | 0.0619 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0105 | 0.1168 | 0.1165 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0017 | 0.0014 | 0.001 |
Loa Loa (eye worm) | orotate phosphoribosyltransferase | 0.0062 | 0.0607 | 0.1072 |
Schistosoma mansoni | myosin xvIII | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0105 | 0.1168 | 0.1165 |
Echinococcus multilocularis | g protein coupled receptor | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0042 | 0.0347 | 0.0619 |
Brugia malayi | Serotonin receptor | 0.0017 | 0.0014 | 0.0018 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | GnHR receptor homolog | 0.0017 | 0.0014 | 0.0018 |
Echinococcus granulosus | 6 phosphofructokinase | 0.0105 | 0.1168 | 0.1165 |
Plasmodium vivax | hypothetical protein, conserved | 0.0042 | 0.0347 | 0.0814 |
Brugia malayi | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase | 0.004 | 0.0314 | 0.0559 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0042 | 0.0347 | 0.0343 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0072 | 0.0734 | 0.13 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
PC50 (functional) | = 4.85 uM | Cytotoxicity against human PANC1 cells assessed as cell viability after 3 hrs by WST-8 cells | ChEMBL. | 23287053 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.