Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog | 0.0232 | 0.0438 | 0.0462 |
Schistosoma mansoni | voltage-gated potassium channel KCNQ | 0.0232 | 0.0438 | 0.0423 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0232 | 0.0438 | 0.0423 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0232 | 0.0438 | 0.0462 |
Schistosoma mansoni | two-pore calcium channel | 0.0232 | 0.0438 | 0.0423 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0325 | 0.0681 | 0.0781 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0467 | 0.1056 | 0.1221 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0325 | 0.0681 | 0.0781 |
Echinococcus multilocularis | cyclic nucleotide gated cation channel | 0.0467 | 0.1056 | 0.1139 |
Trichomonas vaginalis | soluble guanylate cyclase gcy, putative | 0.0325 | 0.0681 | 0.0781 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0325 | 0.0681 | 0.0781 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0325 | 0.0681 | 0.0781 |
Echinococcus multilocularis | potassium voltage gated channel protein | 0.0232 | 0.0438 | 0.0462 |
Schistosoma mansoni | voltage-gated potassium channel | 0.1024 | 0.2525 | 0.2513 |
Schistosoma mansoni | transient receptor potential channel | 0.0232 | 0.0438 | 0.0423 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0325 | 0.0681 | 0.0781 |
Schistosoma mansoni | camp-dependent protein kinase type I-beta regulatory subunit | 0.0467 | 0.1056 | 0.1041 |
Echinococcus multilocularis | calcium activated potassium channel | 0.0232 | 0.0438 | 0.0462 |
Echinococcus multilocularis | voltage dependent calcium channel | 0.0232 | 0.0438 | 0.0462 |
Echinococcus multilocularis | voltage dependent L type calcium channel subunit | 0.0232 | 0.0438 | 0.0462 |
Echinococcus granulosus | ryanodine receptor 44f | 0.0232 | 0.0438 | 0.0462 |
Schistosoma mansoni | 60S ribosomal protein L21 | 0.0557 | 0.1294 | 0.128 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0699 | 0.1669 | 0.1941 |
Leishmania major | cyclic nucleotide-binding protein-like protein | 0.0467 | 0.1056 | 1 |
Echinococcus multilocularis | sodium leak channel non selective protein | 0.0232 | 0.0438 | 0.0462 |
Echinococcus multilocularis | cAMP dependent protein kinase type I beta | 0.0467 | 0.1056 | 0.1139 |
Mycobacterium ulcerans | regulatory protein | 0.0467 | 0.1056 | 1 |
Trichomonas vaginalis | cAMP-dependent protein kinase type I-beta regulatory subunit, putative | 0.0467 | 0.1056 | 0.1221 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.1024 | 0.2525 | 0.2748 |
Echinococcus granulosus | hyperpolarization activated cyclic | 0.0699 | 0.1669 | 0.181 |
Echinococcus granulosus | cGMP dependent protein kinase 1 | 0.0467 | 0.1056 | 0.1139 |
Echinococcus granulosus | two pore calcium channel protein 1 | 0.0232 | 0.0438 | 0.0462 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.3534 | 0.9144 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0467 | 0.1056 | 1 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0232 | 0.0438 | 0.0462 |
Trypanosoma brucei | cyclic nucleotide-binding domain containing protein, putative | 0.0467 | 0.1056 | 1 |
Echinococcus granulosus | cyclic nucleotide gated cation channel | 0.0467 | 0.1056 | 0.1139 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.0699 | 0.1669 | 0.1655 |
Echinococcus granulosus | voltage gated potassium channel | 0.1024 | 0.2525 | 0.2748 |
Echinococcus granulosus | potassium large conductance calcium activated | 0.0232 | 0.0438 | 0.0462 |
Echinococcus multilocularis | voltage gated hydrogen channel 1 | 0.0232 | 0.0438 | 0.0462 |
Echinococcus multilocularis | potassium voltage gated channel subfamily A | 0.0232 | 0.0438 | 0.0462 |
Schistosoma mansoni | voltage-gated potassium channel | 0.1024 | 0.2525 | 0.2513 |
Echinococcus granulosus | short transient receptor potential channel 6 | 0.0232 | 0.0438 | 0.0462 |
Mycobacterium ulcerans | DNA gyrase subunit A | 0.0249 | 0.0482 | 0.352 |
Brugia malayi | Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog | 0.0232 | 0.0438 | 0.0462 |
Schistosoma mansoni | calcium-activated potassium channel | 0.0232 | 0.0438 | 0.0423 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.3301 | 0.8531 | 1 |
Onchocerca volvulus | 0.0467 | 0.1056 | 1 | |
Schistosoma mansoni | hyperpolarization activated cyclic nucleotide-gated potassium channel | 0.0232 | 0.0438 | 0.0423 |
Leishmania major | hypothetical protein, conserved | 0.0467 | 0.1056 | 1 |
Schistosoma mansoni | hyperpolarization activated cyclic nucleotide-gated potassium channel | 0.0467 | 0.1056 | 0.1041 |
Echinococcus granulosus | sodium leak channel non selective protein | 0.0232 | 0.0438 | 0.0462 |
Mycobacterium ulcerans | hypothetical protein | 0.0467 | 0.1056 | 1 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0325 | 0.0681 | 0.0781 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0232 | 0.0438 | 0.0462 |
Echinococcus multilocularis | ryanodine receptor 44f | 0.0232 | 0.0438 | 0.0462 |
Leishmania major | hypothetical protein, unknown function | 0.0467 | 0.1056 | 1 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0325 | 0.0681 | 0.0781 |
Brugia malayi | aryl hydrocarbon receptor nuclear translocator protein, putative | 0.0325 | 0.0681 | 0.0728 |
Echinococcus granulosus | patatin phospholipase domain containing protein | 0.0467 | 0.1056 | 0.1139 |
Echinococcus granulosus | potassium voltage gated channel protein | 0.0232 | 0.0438 | 0.0462 |
Echinococcus granulosus | transient receptor potential gamma protein | 0.0232 | 0.0438 | 0.0462 |
Echinococcus granulosus | hyperpolarization activated cyclic | 0.0699 | 0.1669 | 0.181 |
Echinococcus granulosus | potassium:sodium hyperpolarization activated | 0.0699 | 0.1669 | 0.181 |
Trichomonas vaginalis | guanylate cyclase beta 1 subunit, putative | 0.0325 | 0.0681 | 0.0781 |
Plasmodium falciparum | cAMP-dependent protein kinase regulatory subunit | 0.0467 | 0.1056 | 1 |
Echinococcus multilocularis | potassium voltage gated channel subfamily D | 0.0232 | 0.0438 | 0.0462 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0557 | 0.1294 | 0.128 |
Loa Loa (eye worm) | cyclic-nucleotide gated cation channel | 0.0699 | 0.1669 | 0.181 |
Loa Loa (eye worm) | hypothetical protein | 0.0232 | 0.0438 | 0.0462 |
Brugia malayi | Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog | 0.0232 | 0.0438 | 0.0462 |
Echinococcus granulosus | voltage dependent calcium channel | 0.0232 | 0.0438 | 0.0462 |
Schistosoma mansoni | transient receptor potential cation channel subfamily m member | 0.0232 | 0.0438 | 0.0423 |
Echinococcus granulosus | potassium voltage gated channel subfamily A | 0.0232 | 0.0438 | 0.0462 |
Echinococcus multilocularis | potassium voltage gated channel protein | 0.0232 | 0.0438 | 0.0462 |
Schistosoma mansoni | transient receptor potential cation channel subfamily m member | 0.0232 | 0.0438 | 0.0423 |
Brugia malayi | Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit | 0.0232 | 0.0438 | 0.0462 |
Leishmania major | hypothetical protein, conserved | 0.0467 | 0.1056 | 1 |
Echinococcus granulosus | potassium voltage gated channel subfamily D | 0.0232 | 0.0438 | 0.0462 |
Onchocerca volvulus | 0.0467 | 0.1056 | 1 | |
Onchocerca volvulus | Transient receptor potential cation channel trpm homolog | 0.0232 | 0.0438 | 0.4059 |
Brugia malayi | Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog | 0.0232 | 0.0438 | 0.0462 |
Brugia malayi | cation channel family protein | 0.0232 | 0.0438 | 0.0462 |
Brugia malayi | Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog | 0.1024 | 0.2525 | 0.2748 |
Echinococcus multilocularis | potassium voltage gated channel protein | 0.0232 | 0.0438 | 0.0462 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0325 | 0.0681 | 0.0781 |
Echinococcus multilocularis | potassium voltage gated channel subfamily KQT | 0.0232 | 0.0438 | 0.0462 |
Echinococcus granulosus | two pore calcium channel protein 2 | 0.0232 | 0.0438 | 0.0462 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0325 | 0.0681 | 0.0781 |
Echinococcus multilocularis | voltage dependent calcium channel | 0.0232 | 0.0438 | 0.0462 |
Echinococcus multilocularis | cAMP dependent protein kinase type II regulatory | 0.0467 | 0.1056 | 0.1139 |
Loa Loa (eye worm) | hypothetical protein | 0.0467 | 0.1056 | 0.1139 |
Loa Loa (eye worm) | hypothetical protein | 0.3067 | 0.7913 | 0.8652 |
Onchocerca volvulus | 0.0232 | 0.0438 | 0.4059 | |
Schistosoma mansoni | voltage-gated potassium channel | 0.0232 | 0.0438 | 0.0423 |
Echinococcus multilocularis | voltage gated potassium channel | 0.1024 | 0.2525 | 0.2748 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0325 | 0.0681 | 0.0781 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0325 | 0.0681 | 0.0781 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0232 | 0.0438 | 0.0423 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0467 | 0.1056 | 0.1221 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0232 | 0.0438 | 0.0462 |
Mycobacterium tuberculosis | Probable conserved transmembrane transport protein | 0.0467 | 0.1056 | 1 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.0699 | 0.1669 | 0.1655 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0467 | 0.1056 | 1 |
Trichomonas vaginalis | adenylate cyclase type III, putative | 0.0325 | 0.0681 | 0.0781 |
Schistosoma mansoni | transient receptor potential channel 4 | 0.0232 | 0.0438 | 0.0423 |
Echinococcus granulosus | potassium voltage gated channel subfamily D | 0.0232 | 0.0438 | 0.0462 |
Echinococcus granulosus | potassium voltage gated channel subfamily C | 0.0232 | 0.0438 | 0.0462 |
Leishmania major | protein kinase, putative | 0.0467 | 0.1056 | 1 |
Brugia malayi | Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit | 0.0232 | 0.0438 | 0.0462 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0325 | 0.0681 | 0.0781 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0232 | 0.0438 | 0.4059 |
Echinococcus multilocularis | potassium large conductance calcium activated | 0.0232 | 0.0438 | 0.0462 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0232 | 0.0438 | 0.0423 |
Echinococcus granulosus | shaker cognate | 0.0232 | 0.0438 | 0.0462 |
Echinococcus granulosus | cyclic nucleotide gated cation channel | 0.0699 | 0.1669 | 0.181 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0467 | 0.1056 | 0.1041 |
Toxoplasma gondii | transporter, cation channel family protein | 0.0232 | 0.0438 | 0.4059 |
Trichomonas vaginalis | adenylate cyclase type IX, putative | 0.0325 | 0.0681 | 0.0781 |
Loa Loa (eye worm) | hypothetical protein | 0.0232 | 0.0438 | 0.0462 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0325 | 0.0681 | 0.0781 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0232 | 0.0438 | 0.0423 |
Brugia malayi | cAMP-dependent protein kinase regulatory chain, putative | 0.0467 | 0.1056 | 0.1139 |
Schistosoma mansoni | transient receptor potential cation channel subfamily m member | 0.0232 | 0.0438 | 0.0423 |
Echinococcus granulosus | potassium voltage gated channel protein | 0.0232 | 0.0438 | 0.0462 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0232 | 0.0438 | 0.0423 |
Echinococcus multilocularis | cyclic nucleotide gated cation channel | 0.0699 | 0.1669 | 0.181 |
Schistosoma mansoni | calcium channel voltage-dependent p/q type alpha 1a-related | 0.0232 | 0.0438 | 0.0423 |
Leishmania major | protein kinase, putative | 0.0467 | 0.1056 | 1 |
Brugia malayi | Cyclic-nucleotide gated cation channel, C. elegans tax-4 ortholog | 0.0467 | 0.1056 | 0.1139 |
Echinococcus granulosus | voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 | 0.0232 | 0.0438 | 0.0462 |
Toxoplasma gondii | cyclic nucleotide-binding domain-containing protein | 0.0467 | 0.1056 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0232 | 0.0438 | 0.0462 |
Echinococcus granulosus | potassium voltage gated channel protein | 0.0232 | 0.0438 | 0.0462 |
Trichomonas vaginalis | adenylate cyclase type VI, putative | 0.0325 | 0.0681 | 0.0781 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0232 | 0.0438 | 0.0423 |
Mycobacterium ulcerans | transmembrane transport protein | 0.0467 | 0.1056 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0232 | 0.0438 | 0.0462 |
Chlamydia trachomatis | cAMP-dependent protein kinase regulatory subunit | 0.0467 | 0.1056 | 1 |
Echinococcus multilocularis | voltage dependent L type calcium channel subunit | 0.0232 | 0.0438 | 0.0462 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0232 | 0.0438 | 0.0462 |
Trichomonas vaginalis | adenylate cyclase type vIII, putative | 0.0325 | 0.0681 | 0.0781 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0325 | 0.0681 | 0.0781 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0325 | 0.0681 | 0.0781 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.3534 | 0.9144 | 1 |
Plasmodium vivax | rap guanine nucleotide exchange factor, putative | 0.0467 | 0.1056 | 1 |
Trichomonas vaginalis | adenylate cyclase type IX, putative | 0.0325 | 0.0681 | 0.0781 |
Echinococcus multilocularis | cGMP dependent protein kinase 1 | 0.0467 | 0.1056 | 0.1139 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.0467 | 0.1056 | 0.1041 |
Mycobacterium ulcerans | transcriptional regulatory protein | 0.0467 | 0.1056 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0232 | 0.0438 | 0.0462 |
Brugia malayi | cation channel family protein | 0.0232 | 0.0438 | 0.0462 |
Echinococcus granulosus | voltage gated hydrogen channel 1 | 0.0232 | 0.0438 | 0.0462 |
Toxoplasma gondii | cyclic nucleotide-binding domain-containing protein | 0.0467 | 0.1056 | 1 |
Trypanosoma cruzi | inositol 1,4,5-trisphosphate receptor, putative | 0.0232 | 0.0438 | 0.4059 |
Loa Loa (eye worm) | hypothetical protein | 0.0467 | 0.1056 | 0.1139 |
Echinococcus multilocularis | potassium voltage gated channel protein | 0.0232 | 0.0438 | 0.0462 |
Echinococcus granulosus | hypothetical protein | 0.0232 | 0.0438 | 0.0462 |
Toxoplasma gondii | protein kinase G AGC kinase family member PKG | 0.0467 | 0.1056 | 1 |
Echinococcus multilocularis | shaker cognate | 0.0232 | 0.0438 | 0.0462 |
Echinococcus granulosus | cGMP dependent protein kinase | 0.0467 | 0.1056 | 0.1139 |
Echinococcus granulosus | cAMP dependent protein kinase regulatory | 0.0467 | 0.1056 | 0.1139 |
Mycobacterium tuberculosis | Conserved protein | 0.0467 | 0.1056 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0232 | 0.0438 | 0.0462 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0325 | 0.0681 | 0.0781 |
Loa Loa (eye worm) | AGC/PKG protein kinase | 0.0467 | 0.1056 | 0.1139 |
Loa Loa (eye worm) | voltage-gated potassium channel | 0.0232 | 0.0438 | 0.0462 |
Schistosoma mansoni | voltage-gated cation channel | 0.0232 | 0.0438 | 0.0423 |
Onchocerca volvulus | Transient receptor potential cation channel trpm homolog | 0.0232 | 0.0438 | 0.4059 |
Loa Loa (eye worm) | voltage-dependent calcium channel | 0.0232 | 0.0438 | 0.0462 |
Schistosoma mansoni | hyperpolarization activated cyclic nucleotide-gated potassium channel | 0.0699 | 0.1669 | 0.1655 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0232 | 0.0438 | 0.0423 |
Trypanosoma brucei | inositol 1,4,5-trisphosphate receptor | 0.0232 | 0.0438 | 0.4059 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0325 | 0.0681 | 0.0781 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0699 | 0.1669 | 0.1941 |
Echinococcus multilocularis | cyclic nucleotide gated cation channel | 0.0467 | 0.1056 | 0.1139 |
Trypanosoma brucei | STE group serine/threonine-protein kinase, putative | 0.0325 | 0.0681 | 0.6396 |
Schistosoma mansoni | similar to Protein C20orf152 homolog | 0.0467 | 0.1056 | 0.1041 |
Loa Loa (eye worm) | hypothetical protein | 0.0232 | 0.0438 | 0.0462 |
Schistosoma mansoni | camp-dependent protein kinase type I-beta regulatory subunit | 0.0467 | 0.1056 | 0.1041 |
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.0232 | 0.0438 | 0.0462 |
Toxoplasma gondii | cyclic nucleotide-binding domain-containing protein | 0.0467 | 0.1056 | 1 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0325 | 0.0681 | 0.0781 |
Loa Loa (eye worm) | hypothetical protein | 0.0232 | 0.0438 | 0.0462 |
Echinococcus granulosus | calcium activated potassium channel | 0.0232 | 0.0438 | 0.0462 |
Mycobacterium tuberculosis | Probable glutamine-transport ATP-binding protein ABC transporter GlnQ | 0.0467 | 0.1056 | 1 |
Schistosoma mansoni | voltage-gated ion channel | 0.0232 | 0.0438 | 0.0423 |
Mycobacterium tuberculosis | Probable conserved transmembrane protein | 0.0467 | 0.1056 | 1 |
Echinococcus multilocularis | transient receptor potential gamma protein | 0.0232 | 0.0438 | 0.0462 |
Schistosoma mansoni | high voltage-activated calcium channel Cav1 | 0.0232 | 0.0438 | 0.0423 |
Loa Loa (eye worm) | hypothetical protein | 0.1024 | 0.2525 | 0.2748 |
Trypanosoma cruzi | regulatory subunit of protein kinase a-like protein, putative | 0.0467 | 0.1056 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0325 | 0.0681 | 0.0781 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0467 | 0.1056 | 0.1041 |
Loa Loa (eye worm) | hypothetical protein | 0.0232 | 0.0438 | 0.0462 |
Loa Loa (eye worm) | hypothetical protein | 0.0232 | 0.0438 | 0.0462 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0325 | 0.0681 | 0.0781 |
Loa Loa (eye worm) | hypothetical protein | 0.0232 | 0.0438 | 0.0462 |
Echinococcus multilocularis | hyperpolarization activated cyclic | 0.0699 | 0.1669 | 0.181 |
Echinococcus granulosus | Potassium voltage gated channel protein Shaw | 0.0232 | 0.0438 | 0.0462 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0325 | 0.0681 | 0.0781 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0325 | 0.0681 | 0.0781 |
Echinococcus multilocularis | conserved hypothetical protein | 0.0232 | 0.0438 | 0.0462 |
Plasmodium vivax | DNA gyrase subunit A, putative | 0.0249 | 0.0482 | 0.448 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0325 | 0.0681 | 0.0781 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0325 | 0.0681 | 0.0781 |
Echinococcus granulosus | short transient receptor potential channel 6 | 0.0232 | 0.0438 | 0.0462 |
Echinococcus multilocularis | cAMP dependent protein kinase regulatory | 0.0467 | 0.1056 | 0.1139 |
Plasmodium falciparum | cGMP-dependent protein kinase | 0.0467 | 0.1056 | 1 |
Echinococcus granulosus | cAMP dependent protein kinase type I beta | 0.0467 | 0.1056 | 0.1139 |
Trichomonas vaginalis | adenylate cyclase type, putative | 0.0325 | 0.0681 | 0.0781 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0325 | 0.0681 | 0.0781 |
Chlamydia trachomatis | DNA gyrase subunit A | 0.0249 | 0.0482 | 0.352 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0325 | 0.0681 | 0.0781 |
Mycobacterium tuberculosis | DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) | 0.0249 | 0.0482 | 0.352 |
Schistosoma mansoni | voltage-dependent calcium channel | 0.0232 | 0.0438 | 0.0423 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0325 | 0.0681 | 0.0781 |
Brugia malayi | Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog | 0.0232 | 0.0438 | 0.0462 |
Echinococcus granulosus | cyclic nucleotide gated cation channel alpha 3 | 0.0699 | 0.1669 | 0.181 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0325 | 0.0681 | 0.0781 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.0467 | 0.1056 | 1 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0699 | 0.1669 | 0.1655 |
Loa Loa (eye worm) | cAMP-dependent protein kinase regulatory subunit | 0.0467 | 0.1056 | 0.1139 |
Mycobacterium ulcerans | hypothetical protein | 0.0467 | 0.1056 | 1 |
Trichomonas vaginalis | soluble guanylate cyclase gcy, putative | 0.0325 | 0.0681 | 0.0781 |
Trichomonas vaginalis | guanylate cyclase beta 2 subunit, putative | 0.0325 | 0.0681 | 0.0781 |
Plasmodium vivax | DNA gyrase subunit B, putative | 0.0131 | 0.0171 | 0.1482 |
Echinococcus multilocularis | cGMP dependent protein kinase 1 | 0.0467 | 0.1056 | 0.1139 |
Echinococcus multilocularis | hyperpolarization activated cyclic | 0.0699 | 0.1669 | 0.181 |
Plasmodium falciparum | DNA gyrase subunit A | 0.0249 | 0.0482 | 0.448 |
Trypanosoma brucei | Voltage-dependent calcium channel subunit, putative | 0.0232 | 0.0438 | 0.4059 |
Trichomonas vaginalis | soluble guanylate cyclase gcy, putative | 0.0325 | 0.0681 | 0.0781 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0232 | 0.0438 | 0.0462 |
Leishmania major | regulatory subunit of protein kinase a-like protein | 0.0467 | 0.1056 | 1 |
Trypanosoma brucei | cAMP binding protein, putative | 0.0467 | 0.1056 | 1 |
Echinococcus multilocularis | potassium:sodium hyperpolarization activated | 0.0699 | 0.1669 | 0.181 |
Loa Loa (eye worm) | hypothetical protein | 0.0232 | 0.0438 | 0.0462 |
Trypanosoma cruzi | Voltage-dependent calcium channel subunit, putative | 0.0232 | 0.0438 | 0.4059 |
Schistosoma mansoni | camp-dependent protein kinase type II-alpha regulatory subunit | 0.0467 | 0.1056 | 0.1041 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0232 | 0.0438 | 0.0462 |
Brugia malayi | Voltage-gated calcium channel, alpha subunit | 0.0232 | 0.0438 | 0.0462 |
Toxoplasma gondii | hypothetical protein | 0.0232 | 0.0438 | 0.4059 |
Trichomonas vaginalis | adenylate cyclase type III, putative | 0.0325 | 0.0681 | 0.0781 |
Schistosoma mansoni | camp-dependent protein kinase regulatory chain | 0.0467 | 0.1056 | 0.1041 |
Loa Loa (eye worm) | ion channel NompC | 0.0232 | 0.0438 | 0.0462 |
Brugia malayi | Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog | 0.0232 | 0.0438 | 0.0462 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0325 | 0.0681 | 0.0781 |
Echinococcus granulosus | voltage gated potassium channel | 0.0232 | 0.0438 | 0.0462 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0325 | 0.0681 | 0.0781 |
Plasmodium falciparum | DNA gyrase subunit B | 0.0131 | 0.0171 | 0.1482 |
Echinococcus granulosus | voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu | 0.0232 | 0.0438 | 0.0462 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0325 | 0.0681 | 0.0781 |
Brugia malayi | Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog | 0.0232 | 0.0438 | 0.0462 |
Echinococcus granulosus | voltage dependent L type calcium channel subunit|voltage dependent calcium channel | 0.0232 | 0.0438 | 0.0462 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0325 | 0.0681 | 0.0781 |
Echinococcus multilocularis | sodium channel protein | 0.0232 | 0.0438 | 0.0462 |
Trichomonas vaginalis | intestinal guanylate cyclase, putative | 0.0325 | 0.0681 | 0.0781 |
Trichomonas vaginalis | adenylate cyclase type, putative | 0.0325 | 0.0681 | 0.0781 |
Loa Loa (eye worm) | hypothetical protein | 0.0232 | 0.0438 | 0.0462 |
Loa Loa (eye worm) | hypothetical protein | 0.0232 | 0.0438 | 0.0462 |
Leishmania major | hypothetical protein, conserved | 0.0467 | 0.1056 | 1 |
Trypanosoma brucei | protein kinase A regulatory subunit | 0.0467 | 0.1056 | 1 |
Echinococcus granulosus | potassium voltage gated channel subfamily D | 0.0232 | 0.0438 | 0.0462 |
Trichomonas vaginalis | adenylate cyclase type, putative | 0.0325 | 0.0681 | 0.0781 |
Brugia malayi | Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit | 0.0232 | 0.0438 | 0.0462 |
Schistosoma mansoni | vesicular amine transporter | 0.0232 | 0.0438 | 0.0423 |
Loa Loa (eye worm) | voltage-gated potassium channel | 0.0232 | 0.0438 | 0.0462 |
Loa Loa (eye worm) | hypothetical protein | 0.0699 | 0.1669 | 0.181 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0325 | 0.0681 | 0.0781 |
Trypanosoma brucei | cAMP response protein 1, putative | 0.0467 | 0.1056 | 1 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0232 | 0.0438 | 0.0462 |
Plasmodium vivax | CAMP-dependent protein kinase regulatory subunit, putative | 0.0467 | 0.1056 | 1 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0467 | 0.1056 | 1 |
Echinococcus multilocularis | potassium voltage gated channel subfamily C | 0.0232 | 0.0438 | 0.0462 |
Trichomonas vaginalis | cAMP-dependent protein kinase regulatory subunit, putative | 0.0467 | 0.1056 | 0.1221 |
Echinococcus multilocularis | voltage dependent calcium channel type d subunit | 0.0232 | 0.0438 | 0.0462 |
Loa Loa (eye worm) | hypothetical protein | 0.0232 | 0.0438 | 0.0462 |
Echinococcus granulosus | TRP transient receptor potential channel | 0.0232 | 0.0438 | 0.0462 |
Loa Loa (eye worm) | hypothetical protein | 0.0232 | 0.0438 | 0.0462 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0325 | 0.0681 | 0.0781 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.0232 | 0.0438 | 0.0423 |
Schistosoma mansoni | cyclic nucleotide-gated ion channel | 0.0467 | 0.1056 | 0.1041 |
Schistosoma mansoni | transient receptor potential channel | 0.0232 | 0.0438 | 0.0423 |
Schistosoma mansoni | transient receptor potential cation channel subfamily m member | 0.0232 | 0.0438 | 0.0423 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0325 | 0.0681 | 0.0781 |
Trichomonas vaginalis | adenylyl cyclase type V, putative | 0.0325 | 0.0681 | 0.0781 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.3301 | 0.8531 | 1 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.3534 | 0.9144 | 1 |
Wolbachia endosymbiont of Brugia malayi | DNA gyrase subunit A | 0.0249 | 0.0482 | 1 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0232 | 0.0438 | 0.0423 |
Echinococcus multilocularis | TRP (transient receptor potential) channel | 0.0232 | 0.0438 | 0.0462 |
Entamoeba histolytica | DNA topoisomerase II, putative | 0.0073 | 0.0017 | 0.5 |
Treponema pallidum | cyclic nucleotide binding protein | 0.0467 | 0.1056 | 1 |
Schistosoma mansoni | ryanodine receptor related | 0.0232 | 0.0438 | 0.0423 |
Loa Loa (eye worm) | hypothetical protein | 0.0232 | 0.0438 | 0.0462 |
Trypanosoma cruzi | cyclic nucleotide-binding domain containing protein, putative | 0.0467 | 0.1056 | 1 |
Echinococcus granulosus | voltage gated sodium channel Nav1 alpha subunit | 0.0232 | 0.0438 | 0.0462 |
Leishmania major | protein kinase A regulatory subunit, putative | 0.0467 | 0.1056 | 1 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0325 | 0.0681 | 0.0781 |
Schistosoma mansoni | hypothetical protein | 0.0325 | 0.0681 | 0.0666 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0232 | 0.0438 | 0.0462 |
Schistosoma mansoni | transient receptor potential channel | 0.0232 | 0.0438 | 0.0423 |
Echinococcus multilocularis | potassium voltage gated channel subfamily D | 0.0232 | 0.0438 | 0.0462 |
Brugia malayi | ion channel NompC | 0.0232 | 0.0438 | 0.0462 |
Schistosoma mansoni | camp-dependent protein kinase type II regulatory subunit | 0.0467 | 0.1056 | 0.1041 |
Schistosoma mansoni | inositol 145-trisphosphate receptor | 0.0232 | 0.0438 | 0.0423 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.0699 | 0.1669 | 0.1655 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0325 | 0.0681 | 0.0781 |
Schistosoma mansoni | camp-dependent rap1 guanine-nucleotide exchange factor | 0.0467 | 0.1056 | 0.1041 |
Schistosoma mansoni | high voltage-activated calcium channel Cav2A | 0.0232 | 0.0438 | 0.0423 |
Echinococcus multilocularis | two pore calcium channel protein 2 | 0.0232 | 0.0438 | 0.0462 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0325 | 0.0681 | 0.0781 |
Loa Loa (eye worm) | ryanodine receptor | 0.0232 | 0.0438 | 0.0462 |
Trypanosoma cruzi | cAMP response protein 1, putative | 0.0467 | 0.1056 | 1 |
Loa Loa (eye worm) | cyclic-nucleotide gated cation channel | 0.0699 | 0.1669 | 0.181 |
Brugia malayi | olfactory channel protein osm-9 | 0.0232 | 0.0438 | 0.0462 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.1024 | 0.2525 | 0.2748 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0325 | 0.0681 | 0.0781 |
Schistosoma mansoni | transient receptor potential cation channel subfamily m member | 0.0232 | 0.0438 | 0.0423 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0232 | 0.0438 | 0.0462 |
Loa Loa (eye worm) | voltage-gated calcium channel | 0.0232 | 0.0438 | 0.0462 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0325 | 0.0681 | 0.0781 |
Echinococcus multilocularis | patatin phospholipase domain containing protein | 0.0467 | 0.1056 | 0.1139 |
Trichomonas vaginalis | adenylate cyclase type IX, putative | 0.0325 | 0.0681 | 0.0781 |
Trypanosoma cruzi | Flagellar Member 6 | 0.0467 | 0.1056 | 1 |
Brugia malayi | N-terminal motif family protein | 0.0467 | 0.1056 | 0.1139 |
Mycobacterium tuberculosis | Probable transcriptional regulatory protein Cmr | 0.0467 | 0.1056 | 1 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0467 | 0.1056 | 1 |
Brugia malayi | voltage-dependent calcium channel | 0.0232 | 0.0438 | 0.0462 |
Brugia malayi | hypothetical protein | 0.0232 | 0.0438 | 0.0462 |
Schistosoma mansoni | hypothetical protein | 0.0467 | 0.1056 | 0.1041 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0232 | 0.0438 | 0.0423 |
Echinococcus granulosus | cGMP dependent protein kinase 1 | 0.0467 | 0.1056 | 0.1139 |
Toxoplasma gondii | DNA gyrase/topoisomerase IV, A subunit domain-containing protein | 0.0249 | 0.0482 | 0.448 |
Treponema pallidum | cyclic nucleotide binding protein | 0.0467 | 0.1056 | 1 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0325 | 0.0681 | 0.0781 |
Schistosoma mansoni | hyperpolarization activated cyclic nucleotide-gated potassium channel | 0.0699 | 0.1669 | 0.1655 |
Echinococcus granulosus | potassium channel KvQLT family member kqt 1 | 0.0232 | 0.0438 | 0.0462 |
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.0232 | 0.0438 | 0.0462 |
Schistosoma mansoni | neuropathy target esterase/swiss cheese-related protein | 0.0467 | 0.1056 | 0.1041 |
Brugia malayi | Egg laying defective protein 4 | 0.0467 | 0.1056 | 0.1139 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0325 | 0.0681 | 0.0781 |
Schistosoma mansoni | hypothetical protein | 0.0232 | 0.0438 | 0.0423 |
Echinococcus multilocularis | two pore calcium channel protein 1 | 0.0232 | 0.0438 | 0.0462 |
Leishmania major | hypothetical protein, conserved | 0.0232 | 0.0438 | 0.4059 |
Toxoplasma gondii | transporter, cation channel family protein | 0.0232 | 0.0438 | 0.4059 |
Trypanosoma cruzi | protein kinase A regulatory subunit | 0.0467 | 0.1056 | 1 |
Echinococcus granulosus | cyclic nucleotide gated cation channel | 0.0699 | 0.1669 | 0.181 |
Trichomonas vaginalis | hypothetical protein | 0.0325 | 0.0681 | 0.0781 |
Treponema pallidum | DNA gyrase, subunit A (gyrA) | 0.0249 | 0.0482 | 0.352 |
Treponema pallidum | catabolite gene activator (Crp) | 0.0467 | 0.1056 | 1 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0232 | 0.0438 | 0.0462 |
Echinococcus granulosus | sodium channel protein | 0.0232 | 0.0438 | 0.0462 |
Toxoplasma gondii | cAMP-dependent protein kinase regulatory subunit | 0.0467 | 0.1056 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0467 | 0.1056 | 0.1041 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0232 | 0.0438 | 0.0423 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0325 | 0.0681 | 0.0781 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0232 | 0.0438 | 0.4059 |
Toxoplasma gondii | hypothetical protein | 0.0232 | 0.0438 | 0.4059 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0325 | 0.0681 | 0.0781 |
Leishmania major | calcium channel protein, putative,ion transporter, putative | 0.0232 | 0.0438 | 0.4059 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0325 | 0.0681 | 0.0781 |
Echinococcus granulosus | potassium voltage gated channel protein | 0.0232 | 0.0438 | 0.0462 |
Toxoplasma gondii | cyclic nucleotide-binding domain-containing protein | 0.0467 | 0.1056 | 1 |
Echinococcus multilocularis | transfer RNA-Gly | 0.0232 | 0.0438 | 0.0462 |
Echinococcus granulosus | voltage dependent calcium channel | 0.0232 | 0.0438 | 0.0462 |
Brugia malayi | Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit | 0.0232 | 0.0438 | 0.0462 |
Mycobacterium leprae | Possible transporter protein | 0.0325 | 0.0681 | 0.5917 |
Treponema pallidum | catabolite gene activator | 0.0467 | 0.1056 | 1 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0325 | 0.0681 | 0.0781 |
Trypanosoma cruzi | cAMP binding protein, putative | 0.0467 | 0.1056 | 1 |
Trypanosoma brucei | cyclic nucleotide-binding domain containing protein, putative | 0.0467 | 0.1056 | 1 |
Echinococcus granulosus | potassium voltage gated channel protein | 0.0232 | 0.0438 | 0.0462 |
Brugia malayi | Hypothetical UPF0028 protein ZK370.4 in chromosome III, putative | 0.0467 | 0.1056 | 0.1139 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0325 | 0.0681 | 0.0781 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0467 | 0.1056 | 0.1221 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.3534 | 0.9144 | 1 |
Echinococcus multilocularis | voltage dependent calcium channel type d subunit | 0.0232 | 0.0438 | 0.0462 |
Echinococcus multilocularis | expressed conserved protein | 0.0467 | 0.1056 | 0.1139 |
Trypanosoma cruzi | regulatory subunit of protein kinase a-like protein, putative | 0.0467 | 0.1056 | 1 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0325 | 0.0681 | 0.0781 |
Echinococcus multilocularis | cyclic nucleotide gated cation channel alpha 3 | 0.0699 | 0.1669 | 0.181 |
Schistosoma mansoni | neuropathy target esterase/swiss cheese-related protein | 0.0467 | 0.1056 | 0.1041 |
Brugia malayi | Transient-receptor-potential like protein | 0.0232 | 0.0438 | 0.0462 |
Mycobacterium ulcerans | hypothetical protein | 0.0467 | 0.1056 | 1 |
Trichomonas vaginalis | soluble guanylate cyclase gcy, putative | 0.0325 | 0.0681 | 0.0781 |
Trichomonas vaginalis | adenylate cyclase type IX, putative | 0.0325 | 0.0681 | 0.0781 |
Loa Loa (eye worm) | calcium channel | 0.0232 | 0.0438 | 0.0462 |
Loa Loa (eye worm) | hypothetical protein | 0.0232 | 0.0438 | 0.0462 |
Giardia lamblia | CAMP-dependent protein kinase regulatory chain | 0.0467 | 0.1056 | 1 |
Leishmania major | hypothetical protein, unknown function | 0.0232 | 0.0438 | 0.4059 |
Brugia malayi | Ryanodine Receptor TM 4-6 family protein | 0.0232 | 0.0438 | 0.0462 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0467 | 0.1056 | 1 |
Trypanosoma cruzi | cAMP response protein 1 | 0.0467 | 0.1056 | 1 |
Echinococcus granulosus | cAMP dependent protein kinase type II regulatory | 0.0467 | 0.1056 | 0.1139 |
Brugia malayi | Cyclic-nucleotide gated cation channel | 0.0699 | 0.1669 | 0.181 |
Loa Loa (eye worm) | hypothetical protein | 0.0232 | 0.0438 | 0.0462 |
Toxoplasma gondii | transporter, cation channel family protein | 0.0232 | 0.0438 | 0.4059 |
Echinococcus multilocularis | potassium voltage gated channel subfamily D | 0.0232 | 0.0438 | 0.0462 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0325 | 0.0681 | 0.0781 |
Trypanosoma brucei | Flagellar Member 6 | 0.0467 | 0.1056 | 1 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0325 | 0.0681 | 0.0781 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0232 | 0.0438 | 0.0462 |
Echinococcus granulosus | single minded 2 | 0.0325 | 0.0681 | 0.0728 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0232 | 0.0438 | 0.0423 |
Echinococcus multilocularis | voltage gated potassium channel | 0.0232 | 0.0438 | 0.0462 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0325 | 0.0681 | 0.0781 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0325 | 0.0681 | 0.0781 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0325 | 0.0681 | 0.0781 |
Trichomonas vaginalis | soluble guanylate cyclase gcy, putative | 0.0325 | 0.0681 | 0.0781 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (ADMET) | = 96.5 % | Cytotoxicity against human MDA-MB-231 cells assessed as colony formation at 10 uM after 2 weeks relative to control | ChEMBL. | 23526571 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.