TDR Targets

Basic information

Technical information

TDR Targets ID: 1727129
Name: benzene-1,3-disulfonamide
MW: 236.269 | Formula: C6H8N2O4S2
H donors: 2 H acceptors: 4 LogP: -0.95 Rotable bonds: 2
Rule of 5 violations (Lipinski): 1
SMILES: NS(=O)(=O)c1cccc(c1)S(=O)(=O)N
InChi: 1S/C6H8N2O4S2/c7-13(9,10)5-2-1-3-6(4-5)14(8,11)12/h1-4H,(H2,7,9,10)(H2,8,11,12)
InChiKey: HUYYFHGIHVULSU-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

3701-01-7
ZINC02165129
BAS 00085131
Benzene-1,3-disulfonic acid diamide
C14182
m-Benzenedisulfonamide
ST5000091

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Anopheles gambiae	AGAP002992-PA	Starlite/ChEMBL	References
Thalassiosira weissflogii	Delta carbonic anhydrase	Starlite/ChEMBL	References
Homo sapiens	carbonic anhydrase I	Starlite/ChEMBL	References
Homo sapiens	carbonic anhydrase II	Starlite/ChEMBL	References

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Trypanosoma brucei gambiense	carbonic anhydrase-like protein	Get druggable targets OG5_127628	All targets in OG5_127628
Trypanosoma congolense	carbonic anhydrase-like protein	Get druggable targets OG5_127628	All targets in OG5_127628
Echinococcus granulosus	carbonic anhydrase II	Get druggable targets OG5_127628	All targets in OG5_127628
Loa Loa (eye worm)	carbonic anhydrase 3	Get druggable targets OG5_127628	All targets in OG5_127628
Trypanosoma cruzi	carbonic anhydrase-like protein, putative	Get druggable targets OG5_127628	All targets in OG5_127628
Leishmania infantum	carbonic anhydrase family protein, putative	Get druggable targets OG5_127503	All targets in OG5_127503
Schistosoma japonicum	ko:K01672 carbonic anhydrase [EC4.2.1.1], putative	Get druggable targets OG5_127503	All targets in OG5_127503
Mycobacterium leprae	CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE)	Get druggable targets OG5_127503	All targets in OG5_127503
Schistosoma mansoni	carbonic anhydrase	Get druggable targets OG5_127503	All targets in OG5_127503
Brugia malayi	Eukaryotic-type carbonic anhydrase family protein	Get druggable targets OG5_127628	All targets in OG5_127628
Candida albicans	Involved in protection against oxidative damage	Get druggable targets OG5_127503	All targets in OG5_127503
Leishmania braziliensis	carbonic anhydrase-like protein	Get druggable targets OG5_127628	All targets in OG5_127628
Loa Loa (eye worm)	eukaryotic-type carbonic anhydrase	Get druggable targets OG5_127628	All targets in OG5_127628
Mycobacterium ulcerans	carbonic anhydrase	Get druggable targets OG5_127503	All targets in OG5_127503
Leishmania mexicana	carbonic anhydrase family protein, putative	Get druggable targets OG5_127503	All targets in OG5_127503
Leishmania infantum	carbonic anhydrase-like protein	Get druggable targets OG5_127628	All targets in OG5_127628
Leishmania major	carbonic anhydrase-like protein	Get druggable targets OG5_127628	All targets in OG5_127628
Brugia malayi	Putative carbonic anhydrase 5 precursor	Get druggable targets OG5_127628	All targets in OG5_127628
Echinococcus multilocularis	carbonic anhydrase II	Get druggable targets OG5_127628	All targets in OG5_127628
Leishmania donovani	carbonic anhydrase-like protein	Get druggable targets OG5_127628	All targets in OG5_127628
Candida albicans	Involved in protection against oxidative damage	Get druggable targets OG5_127503	All targets in OG5_127503
Schistosoma mansoni	carbonic anhydrase II (carbonate dehydratase II)	Get druggable targets OG5_127628	All targets in OG5_127628
Schistosoma japonicum	ko:K01672 carbonic anhydrase [EC4.2.1.1], putative	Get druggable targets OG5_127628	All targets in OG5_127628
Trypanosoma brucei	carbonic anhydrase-like protein	Get druggable targets OG5_127628	All targets in OG5_127628
Leishmania donovani	carbonic anhydrase family protein, putative	Get druggable targets OG5_127503	All targets in OG5_127503
Schistosoma mansoni	carbonic anhydrase II (carbonate dehydratase II)	Get druggable targets OG5_127628	All targets in OG5_127628
Mycobacterium tuberculosis	Beta-carbonic anhydrase CanB	Get druggable targets OG5_127503	All targets in OG5_127503
Entamoeba histolytica	carbonic anhydrase, putative	Get druggable targets OG5_127503	All targets in OG5_127503
Leishmania mexicana	carbonic anhydrase-like protein	Get druggable targets OG5_127628	All targets in OG5_127628
Trypanosoma cruzi	carbonic anhydrase-like protein, putative	Get druggable targets OG5_127628	All targets in OG5_127628
Trypanosoma congolense	carbonic anhydrase-like protein	Get druggable targets OG5_127628	All targets in OG5_127628
Leishmania braziliensis	carbonic anhydrase family protein, putative	Get druggable targets OG5_127503	All targets in OG5_127503
Leishmania major	carbonic anhydrase family protein, putative	Get druggable targets OG5_127503	All targets in OG5_127503

By sequence similarity to non orthologous known druggable targets

Species	Potential target	Known druggable target	Length	Alignment span	Identity
Trypanosoma brucei	carbonic anhydrase-like protein	carbonic anhydrase I	261 aa	281 aa	25.3 %
Brugia malayi	Carbonic anhydrase like protein 2 precursor	carbonic anhydrase II	260 aa	259 aa	32.0 %
Mycobacterium tuberculosis	Probable transmembrane carbonic anhydrase (carbonate dehydratase) (carbonic dehydratase)	AGAP002992-PA	255 aa	226 aa	31.9 %

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus granulosus	carbonic anhydrase	0.0067	0.2186	0.2925
Trypanosoma brucei	DNA polymerase kappa, putative	0.0017	0.0303	0.0312
Schistosoma mansoni	hypothetical protein	0.0149	0.5259	0.5259
Trypanosoma brucei	DNA polymerase kappa, putative	0.0017	0.0303	0.0312
Entamoeba histolytica	fructose-1,6-bisphosphate aldolase, putative	0.0257	0.9313	0.9291
Trypanosoma brucei	DNA polymerase kappa, putative	0.0017	0.0303	0.0312
Giardia lamblia	Kinase, CMGC MAPK	0.0045	0.1348	0.116
Mycobacterium ulcerans	aldehyde dehydrogenase	0.0053	0.1671	0.141
Schistosoma mansoni	hypothetical protein	0.0067	0.2186	0.2186
Brugia malayi	Eukaryotic-type carbonic anhydrase family protein	0.0067	0.2186	0.2925
Leishmania major	carbonic anhydrase-like protein	0.0181	0.6451	0.634
Mycobacterium ulcerans	aldehyde dehydrogenase	0.0053	0.1671	0.141
Schistosoma mansoni	carbonic anhydrase-related	0.0067	0.2186	0.2186
Trypanosoma brucei	DNA polymerase kappa, putative	0.0017	0.0303	0.0312
Brugia malayi	Iron-sulfur cluster assembly accessory protein	0.0042	0.1258	0.1684
Trypanosoma cruzi	mitogen-activated protein kinase 11, putative	0.0045	0.1348	0.17
Leishmania major	aldehyde dehydrogenase, mitochondrial precursor	0.0053	0.1671	0.141
Schistosoma mansoni	aldehyde dehydrogenase	0.0053	0.1671	0.1671
Schistosoma mansoni	carbonic anhydrase-related	0.0067	0.2186	0.2186
Trypanosoma brucei	protein kinase, putative	0.0045	0.1348	0.1958
Echinococcus granulosus	mitogen activated protein kinase	0.0045	0.1348	0.1805
Schistosoma mansoni	hypothetical protein	0.0042	0.1258	0.1258
Trypanosoma cruzi	mitogen activated protein kinase 2, putative	0.0045	0.1348	0.17
Mycobacterium ulcerans	fructose-bisphosphate aldolase	0.0126	0.4379	0.4203
Echinococcus granulosus	carbonic anhydrase	0.0067	0.2186	0.2925
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0257	0.9313	1
Entamoeba histolytica	fructose-1,6-bisphosphate aldolase, putative	0.0257	0.9313	0.9291
Trypanosoma brucei	DNA polymerase IV, putative	0.0017	0.0303	0.0312
Echinococcus multilocularis	terminal deoxycytidyl transferase rev1	0.0017	0.0303	0.0406
Mycobacterium tuberculosis	Probable fructose-bisphosphate aldolase Fba	0.0126	0.4379	0.7795
Schistosoma mansoni	survival motor neuron protein	0.0042	0.1258	0.1258
Trichomonas vaginalis	CMGC family protein kinase	0.0045	0.1348	0.116
Echinococcus granulosus	dna polymerase kappa	0.0017	0.0303	0.0406
Loa Loa (eye worm)	eukaryotic-type carbonic anhydrase	0.0067	0.2186	0.2925
Loa Loa (eye worm)	MH2 domain-containing protein	0.0105	0.3607	0.4828
Trypanosoma brucei	DNA polymerase kappa, putative	0.0017	0.0303	0.0312
Loa Loa (eye worm)	ImpB/MucB/SamB family protein	0.0017	0.0303	0.0406
Trichomonas vaginalis	conserved hypothetical protein	0.0119	0.4135	0.4253
Brugia malayi	Carbonic anhydrase like protein 2 precursor	0.0067	0.2186	0.2925
Loa Loa (eye worm)	carbonic anhydrase 3	0.0181	0.6451	0.8635
Echinococcus multilocularis	carbonic anhydrase	0.0067	0.2186	0.2925
Trypanosoma brucei	DNA polymerase eta, putative	0.0017	0.0303	0.0312
Echinococcus granulosus	mitogen activated protein kinase 3	0.0045	0.1348	0.1805
Brugia malayi	ImpB/MucB/SamB family protein	0.0017	0.0303	0.0406
Schistosoma mansoni	DNA polymerase eta	0.0017	0.0303	0.0303
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0257	0.9313	1
Trypanosoma brucei	DNA polymerase kappa, putative	0.0017	0.0303	0.0312
Echinococcus granulosus	carbonic anhydrase II	0.0181	0.6451	0.8635
Echinococcus multilocularis	mitogen activated protein kinase	0.0045	0.1348	0.1805
Mycobacterium tuberculosis	Probable transmembrane carbonic anhydrase (carbonate dehydratase) (carbonic dehydratase)	0.0119	0.4135	0.7329
Trypanosoma brucei	DNA polymerase kappa, putative	0.0017	0.0303	0.0312
Schistosoma mansoni	hypothetical protein	0.0149	0.5259	0.5259
Trypanosoma brucei	DNA polymerase IV, putative	0.0017	0.0303	0.0312
Schistosoma mansoni	rab geranylgeranyl transferase alpha subunit	0.0017	0.0303	0.0303
Brugia malayi	ImpB/MucB/SamB family protein	0.0017	0.0303	0.0406
Trypanosoma cruzi	mitogen activated protein kinase 4, putative	0.0045	0.1348	0.17
Toxoplasma gondii	hypothetical protein	0.0067	0.2186	1
Echinococcus granulosus	dna polymerase eta	0.0017	0.0303	0.0406
Loa Loa (eye worm)	hypothetical protein	0.0208	0.7471	1
Echinococcus multilocularis	dna polymerase eta	0.0017	0.0303	0.0406
Echinococcus granulosus	aldehyde dehydrogenase mitochondrial	0.0053	0.1671	0.2236
Leishmania major	mitogen activated protein kinase, putative,map kinase, putative	0.0045	0.1348	0.1077
Echinococcus multilocularis	dna polymerase kappa	0.0017	0.0303	0.0406
Onchocerca volvulus		0.0042	0.1258	1
Echinococcus granulosus	carbonic anhydrase	0.0067	0.2186	0.2925
Echinococcus granulosus	geminin	0.0149	0.5259	0.7039
Echinococcus multilocularis	mitogen activated protein kinase 3	0.0045	0.1348	0.1805
Leishmania major	mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440	0.0045	0.1348	0.1077
Schistosoma mansoni	carbonic anhydrase II (carbonate dehydratase II)	0.0181	0.6451	0.6451
Treponema pallidum	fructose-bisphosphate aldolase	0.0257	0.9313	0.5
Echinococcus multilocularis	carbonic anhydrase II	0.0181	0.6451	0.8635
Trichomonas vaginalis	CMGC family protein kinase	0.0045	0.1348	0.116
Giardia lamblia	Fructose-bisphosphate aldolase	0.0257	0.9313	1
Loa Loa (eye worm)	eukaryotic-type carbonic anhydrase	0.0181	0.6451	0.8635
Trypanosoma brucei	DNA polymerase kappa, putative	0.0017	0.0303	0.0312
Plasmodium falciparum	carbonic anhydrase	0.0067	0.2186	0.5
Trypanosoma cruzi	carbonic anhydrase-like protein, putative	0.0181	0.6451	1
Brugia malayi	Eukaryotic-type carbonic anhydrase family protein	0.0181	0.6451	0.8635
Echinococcus multilocularis	carbonic anhydrase	0.0067	0.2186	0.2925
Loa Loa (eye worm)	hypothetical protein	0.0067	0.2186	0.2925
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0257	0.9313	1
Mycobacterium tuberculosis	Probable aldehyde dehydrogenase	0.0053	0.1671	0.2615
Brugia malayi	MAP kinase sur-1	0.0045	0.1348	0.1805
Loa Loa (eye worm)	hypothetical protein	0.0067	0.2186	0.2925
Trypanosoma cruzi	mitogen-activated protein kinase 11, putative	0.0045	0.1348	0.17
Brugia malayi	Carbonic anhydrase like protein 2 precursor	0.0067	0.2186	0.2925
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0257	0.9313	1
Echinococcus granulosus	survival motor neuron protein 1	0.0208	0.7471	1
Echinococcus multilocularis	survival motor neuron protein 1	0.0208	0.7471	1
Brugia malayi	hypothetical protein	0.0208	0.7471	1
Trypanosoma brucei	DNA polymerase kappa, putative	0.0017	0.0303	0.0312
Brugia malayi	MH2 domain containing protein	0.0105	0.3607	0.4828
Loa Loa (eye worm)	hypothetical protein	0.0017	0.0303	0.0406
Schistosoma mansoni	serine/threonine protein kinase	0.0045	0.1348	0.1348
Brugia malayi	Putative carbonic anhydrase 5 precursor	0.0181	0.6451	0.8635
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0257	0.9313	1
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0257	0.9313	1
Toxoplasma gondii	aldehyde dehydrogenase	0.0053	0.1671	0.3849
Echinococcus multilocularis	aldehyde dehydrogenase, mitochondrial	0.0053	0.1671	0.2236
Schistosoma mansoni	aldehyde dehydrogenase	0.0053	0.1671	0.1671
Echinococcus multilocularis	carbonic anhydrase	0.0067	0.2186	0.2925
Mycobacterium ulcerans	aldehyde dehydrogenase	0.0053	0.1671	0.141
Trichomonas vaginalis	CMGC family protein kinase	0.0045	0.1348	0.116
Trypanosoma brucei	unspecified product	0.0017	0.0303	0.0312
Brugia malayi	Eukaryotic-type carbonic anhydrase family protein	0.0067	0.2186	0.2925
Trichomonas vaginalis	conserved hypothetical protein	0.0119	0.4135	0.4253
Trypanosoma cruzi	carbonic anhydrase-like protein, putative	0.0181	0.6451	1
Trypanosoma brucei	mitogen activated protein kinase 4, putative	0.0045	0.1348	0.1958
Trypanosoma brucei	carbonic anhydrase-like protein	0.0181	0.6451	1
Trypanosoma brucei	DNA polymerase IV, putative	0.0017	0.0303	0.0312
Loa Loa (eye worm)	transcription factor SMAD2	0.0105	0.3607	0.4828
Echinococcus multilocularis	geminin	0.0149	0.5259	0.7039
Trypanosoma brucei	DNA polymerase kappa, putative	0.0017	0.0303	0.0312
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0257	0.9313	1
Schistosoma mansoni	carbonic anhydrase II (carbonate dehydratase II)	0.0181	0.6451	0.6451
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0257	0.9313	1
Mycobacterium ulcerans	carbonic anhydrase	0.0119	0.4135	0.3952
Schistosoma mansoni	terminal deoxycytidyl transferase	0.0017	0.0303	0.0303
Echinococcus granulosus	terminal deoxycytidyl transferase rev1	0.0017	0.0303	0.0406
Loa Loa (eye worm)	hypothetical protein	0.0067	0.2186	0.2925
Mycobacterium tuberculosis	Beta-carbonic anhydrase CanB	0.0156	0.5531	1
Trichomonas vaginalis	CMGC family protein kinase	0.0045	0.1348	0.116
Schistosoma mansoni	carbonic anhydrase	0.0067	0.2186	0.2186
Loa Loa (eye worm)	CMGC/MAPK/ERK1 protein kinase	0.0045	0.1348	0.1805
Schistosoma mansoni	carbonic anhydrase-related	0.0067	0.2186	0.2186
Brugia malayi	Eukaryotic-type carbonic anhydrase family protein	0.0067	0.2186	0.2925

Activities

Activity type	Activity value	Assay description	Source	Reference
Ki (binding)	= 8 nM	Inhibition of human recombinant carbonic anhydrase 2 by stopped flow CO2 hydration assay	ChEMBL.	23391336
Ki (binding)	= 8 nM	Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assay	ChEMBL.	24314394
Ki (binding)	= 8 nM	Inhibition of human carbonic anhydrase-2 by stopped-flow CO2 hydration assay	ChEMBL.	24792813
Ki (binding)	= 8 nM	Inhibition of human recombinant Carbonic anhydrase 2 compound preincubated for 15 mins by stopped flow CO2 hydrase assay method	ChEMBL.	25129169
Ki (binding)	= 8 nM	Inhibition of human recombinant carbonic anhydrase 2 by stopped-flow CO2 hydration assay	ChEMBL.	25533402
Ki (binding)	= 8 nM	Inhibition of human recombinant carbonic anhydrase 2 by stopped flow CO2 hydrase assay	ChEMBL.	25773015
Ki (binding)	= 8 nM	Inhibition of human carbonic anhydrase 2 pre-incubated for 15 mins by stopped-flow CO2 hydration assay	ChEMBL.	25882523
Ki (binding)	= 8 nM	Inhibition of human recombinant carbonic anhydrase-2 by stopped flow CO2 hydrase assay method	ChEMBL.	26174556
Ki (binding)	= 8 nM	Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by CO2 hydrase stopped flow assay	ChEMBL.	26832216
Ki (binding)	= 79 nM	Inhibition of human recombinant carbonic anhydrase 1 by stopped flow CO2 hydration assay	ChEMBL.	23391336
Ki (binding)	= 79 nM	Inhibition of human carbonic anhydrase-1 by stopped-flow CO2 hydration assay	ChEMBL.	24792813
Ki (binding)	= 79 nM	Inhibition of human recombinant Carbonic anhydrase 1 compound preincubated for 15 mins by stopped flow CO2 hydrase assay method	ChEMBL.	25129169
Ki (binding)	= 79 nM	Inhibition of human recombinant carbonic anhydrase 1 by stopped-flow CO2 hydration assay	ChEMBL.	25533402
Ki (binding)	= 79 nM	Inhibition of human recombinant carbonic anhydrase 1 by stopped flow CO2 hydrase assay	ChEMBL.	25773015
Ki (binding)	= 79 nM	Inhibition of human carbonic anhydrase 1 pre-incubated for 15 mins by stopped-flow CO2 hydration assay	ChEMBL.	25882523
Ki (binding)	= 300 nM	Inhibition of human Carbonic anhydrase2 using CO2 as substrate preincubated for 15 mins by stopped-flow CO2 hydration assay	ChEMBL.	26850377
Ki (binding)	= 300 nM	Inhibition of human carbonic anhydrase 2 incubated for 15 mins by stopped-flow CO2 hydration assay	ChEMBL.	26920803
Ki (binding)	= 300 nM	Inhibition of recombinant human carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydration assay	ChEMBL.	26972117
Ki (binding)	= 424 nM	Inhibition of Thalassiosira weissflogii delta carbonic anhydrase preincubated for 15 mins by stopped flow CO2 hydration assay	ChEMBL.	24314394
Ki (binding)	= 843 nM	Inhibition of Anopheles gambiae carbonic anhydrase pre-incubated for 15 mins by stopped-flow CO2 hydration assay	ChEMBL.	25882523
Ki (binding)	= 28000 nM	Inhibition of human Carbonic anhydrase1 using CO2 as substrate preincubated for 15 mins by stopped-flow CO2 hydration assay	ChEMBL.	26850377
Ki (binding)	= 28000 nM	Inhibition of human carbonic anhydrase 1 incubated for 15 mins by stopped-flow CO2 hydration assay	ChEMBL.	26920803
Ki (binding)	= 28000 nM	Inhibition of recombinant human carbonic anhydrase 1 preincubated for 15 mins by stopped-flow CO2 hydration assay	ChEMBL.	26972117

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL2324868

Bibliographic References

12 literature references were collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 1727129