Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | neuropeptide s receptor | 0.0017 | 0.0014 | 0.001 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.003 | 0.003 |
Onchocerca volvulus | 0.0042 | 0.0347 | 0.0467 | |
Echinococcus multilocularis | uridine 5' monophosphate synthase | 0.0062 | 0.0607 | 0.0604 |
Loa Loa (eye worm) | UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltransferase | 0.004 | 0.0314 | 0.0542 |
Echinococcus multilocularis | g protein coupled receptor | 0.0017 | 0.0014 | 0.001 |
Loa Loa (eye worm) | orotate phosphoribosyltransferase | 0.0062 | 0.0607 | 0.1072 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0046 | 0.0394 | 0.0925 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | GnHR receptor homolog | 0.0017 | 0.0014 | 0.0018 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Loa Loa (eye worm) | thymidylate synthase | 0.0105 | 0.1161 | 0.2071 |
Echinococcus multilocularis | O glycosyltransferase | 0.004 | 0.0316 | 0.0312 |
Entamoeba histolytica | hypothetical protein | 0.0083 | 0.0878 | 0.7104 |
Wolbachia endosymbiont of Brugia malayi | orotidine-5'-phosphate decarboxylase | 0.0626 | 0.7948 | 1 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0028 | 0.0168 | 0.1406 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0042 | 0.0347 | 0.0601 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0083 | 0.0878 | 0.0875 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0347 | 0.0601 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0105 | 0.1161 | 0.1157 |
Mycobacterium tuberculosis | Probable reductase | 0.0105 | 0.1158 | 0.2081 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Mycobacterium ulcerans | hypothetical protein | 0.0042 | 0.0347 | 0.0619 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0717 | 0.1271 |
Trichomonas vaginalis | conserved hypothetical protein | 0.005 | 0.0446 | 0.3796 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0014 | 0.0018 |
Brugia malayi | phosphofructokinase | 0.0105 | 0.1168 | 0.21 |
Echinococcus multilocularis | GPCR, family 2 | 0.0018 | 0.003 | 0.0027 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0014 | 0.0018 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | neuropeptide F receptor | 0.0017 | 0.0014 | 0.0018 |
Leishmania major | orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative,OMPDCase-OPRTase, putative | 0.0062 | 0.0607 | 0.1432 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0017 | 0.0014 | 0.001 |
Toxoplasma gondii | 6-phosphofructokinase | 0.0028 | 0.0168 | 0.0388 |
Schistosoma mansoni | amine GPCR | 0.0017 | 0.0014 | 0.001 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0105 | 0.1168 | 1 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0017 | 0.0014 | 0.0018 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0028 | 0.0168 | 0.1406 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0014 | 0.001 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.0028 | 0.0168 | 0.0388 |
Plasmodium vivax | hypothetical protein, conserved | 0.0042 | 0.0347 | 0.0814 |
Echinococcus granulosus | GPCR family 2 | 0.0018 | 0.003 | 0.0027 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0042 | 0.0347 | 0.0619 |
Loa Loa (eye worm) | glutathione reductase | 0.0046 | 0.0394 | 0.0686 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | somatostatin receptor | 0.0017 | 0.0014 | 0.001 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0105 | 0.1158 | 0.2081 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0042 | 0.0347 | 0.0814 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0042 | 0.0347 | 0.0343 |
Brugia malayi | 6-phosphofructokinase | 0.0105 | 0.1168 | 0.21 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | orexin receptor type 2 | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | alzheimer's disease beta-amyloid related | 0.0122 | 0.1384 | 0.1381 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0014 | 0.0018 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0014 | 0.0018 |
Schistosoma mansoni | opsin-like receptor | 0.0017 | 0.0014 | 0.001 |
Mycobacterium ulcerans | lipase LipD | 0.0042 | 0.0347 | 0.0619 |
Echinococcus granulosus | allatostatin A receptor | 0.0017 | 0.0014 | 0.001 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0105 | 0.1158 | 0.2081 |
Schistosoma mansoni | neuropeptide receptor | 0.0017 | 0.0014 | 0.001 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0105 | 0.1168 | 0.2085 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0116 | 0.1309 | 0.2354 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.0028 | 0.0168 | 0.0388 |
Plasmodium falciparum | orotidine 5'-phosphate decarboxylase | 0.0062 | 0.0607 | 0.1432 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0017 | 0.0014 | 0.001 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0018 | 0.003 | 0.003 |
Schistosoma mansoni | neuropeptide receptor | 0.0017 | 0.0014 | 0.001 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.034 | 0.4218 | 1 |
Schistosoma mansoni | histamine h1 receptor | 0.0017 | 0.0014 | 0.001 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0028 | 0.0168 | 0.1434 |
Loa Loa (eye worm) | phosphofructokinase | 0.0105 | 0.1168 | 0.2085 |
Schistosoma mansoni | amine GPCR | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 0.0734 | 0.073 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0042 | 0.0347 | 0.0814 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0028 | 0.0168 | 0.1406 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0347 | 0.0601 |
Trypanosoma brucei | trypanothione reductase | 0.0046 | 0.0394 | 0.0925 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | AKH receptor | 0.0017 | 0.0014 | 0.0018 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0042 | 0.0347 | 0.0343 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0116 | 0.1309 | 0.2354 |
Schistosoma mansoni | neuropeptide receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0017 | 0.0014 | 0.001 |
Trypanosoma cruzi | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0105 | 0.1168 | 0.2763 |
Trypanosoma cruzi | orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative | 0.0062 | 0.0607 | 0.1432 |
Schistosoma mansoni | myosin xvIII | 0.0017 | 0.0014 | 0.001 |
Giardia lamblia | O-linked GlcNAc transferase | 0.0039 | 0.031 | 1 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | larval opioid receptor | 0.0017 | 0.0014 | 0.0018 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0017 | 0.0014 | 0.0018 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0018 | 0.003 | 0.0027 |
Schistosoma mansoni | o-linked n-acetylglucosamine transferase ogt | 0.004 | 0.0316 | 0.0312 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0017 | 0.0014 | 0.001 |
Trypanosoma brucei | orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative | 0.0062 | 0.0607 | 0.1432 |
Treponema pallidum | NADH oxidase | 0.0016 | 0.0004 | 0.0033 |
Echinococcus multilocularis | 6 phosphofructokinase | 0.0105 | 0.1168 | 0.1165 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | uridine 5' monophosphate synthase | 0.0062 | 0.0607 | 0.0604 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0028 | 0.0168 | 0.0295 |
Brugia malayi | neuropeptide F receptor | 0.0017 | 0.0014 | 0.0018 |
Brugia malayi | Dopamine receptor protein 2 | 0.0017 | 0.0014 | 0.0018 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0042 | 0.0347 | 0.2946 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0018 | 0.003 | 0.0027 |
Brugia malayi | follicle stimulating hormone receptor | 0.0017 | 0.0014 | 0.0018 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.003 | 0.0027 |
Giardia lamblia | Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit | 0.0028 | 0.0168 | 0.5346 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0018 | 0.003 | 0.0048 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0017 | 0.0014 | 0.001 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.164 | 0.2938 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0017 | 0.0014 | 0.001 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase, putative | 0.005 | 0.0446 | 0.1049 |
Echinococcus granulosus | 6 phosphofructokinase | 0.0105 | 0.1168 | 0.1165 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0042 | 0.0347 | 0.0343 |
Mycobacterium ulcerans | beta-lactamase | 0.0042 | 0.0347 | 0.0619 |
Echinococcus multilocularis | neuropeptide receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | somatostatin receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0017 | 0.0014 | 0.001 |
Toxoplasma gondii | phosphofructokinase PFKII | 0.0028 | 0.0168 | 0.0388 |
Echinococcus granulosus | g-protein coupled receptor | 0.0017 | 0.0014 | 0.001 |
Plasmodium falciparum | thioredoxin reductase | 0.0046 | 0.0394 | 0.0925 |
Schistosoma mansoni | opsin-like receptor | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | glutathione reductase | 0.0046 | 0.0394 | 0.0703 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase | 0.004 | 0.0314 | 0.0559 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0042 | 0.0347 | 0.2946 |
Entamoeba histolytica | hypothetical protein | 0.0083 | 0.0878 | 0.7104 |
Schistosoma mansoni | biogenic amine receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | g protein coupled receptor | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | sulfakinin receptor protein | 0.0017 | 0.0014 | 0.0018 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0105 | 0.1168 | 0.2085 |
Echinococcus multilocularis | g protein coupled receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0018 | 0.003 | 0.0027 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0017 | 0.0014 | 0.001 |
Mycobacterium ulcerans | orotidine 5'-phosphate decarboxylase | 0.0062 | 0.0607 | 0.1088 |
Toxoplasma gondii | phosphofructokinase domain-containing protein | 0.0028 | 0.0168 | 0.0388 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0057 | 0.0534 | 0.094 |
Schistosoma mansoni | adenoreceptor | 0.0017 | 0.0014 | 0.001 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0046 | 0.0394 | 0.0925 |
Chlamydia trachomatis | dihydrofolate reductase | 0.0442 | 0.5549 | 1 |
Echinococcus granulosus | dihydrofolate reductase | 0.0442 | 0.5549 | 0.5547 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Toxoplasma gondii | orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase | 0.0062 | 0.0607 | 0.1432 |
Loa Loa (eye worm) | beta-lactamase | 0.0042 | 0.0347 | 0.0601 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0347 | 0.0601 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0042 | 0.0347 | 0.0619 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0017 | 0.0014 | 0.001 |
Mycobacterium tuberculosis | Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) | 0.0105 | 0.1168 | 0.21 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | beta-lactamase | 0.0042 | 0.0347 | 0.0619 |
Trichomonas vaginalis | 6-phosphofructokinase, putative | 0.0028 | 0.0168 | 0.1406 |
Brugia malayi | Amyloid A4 extracellular domain containing protein | 0.0334 | 0.415 | 0.7477 |
Echinococcus granulosus | O glycosyltransferase | 0.004 | 0.0316 | 0.0312 |
Loa Loa (eye worm) | RNA binding protein | 0.0072 | 0.0734 | 0.13 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0105 | 0.1168 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0301 | 0.0297 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0083 | 0.0878 | 0.0875 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | beta-lactamase family protein | 0.0042 | 0.0347 | 0.0619 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0042 | 0.0347 | 0.2946 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0017 | 0.0014 | 0.001 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0116 | 0.1309 | 0.2354 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0017 | 0.0014 | 0.001 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0042 | 0.0347 | 0.0619 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0017 | 0.0014 | 0.001 |
Toxoplasma gondii | thioredoxin reductase | 0.0046 | 0.0394 | 0.0925 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0046 | 0.0394 | 0.039 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0347 | 0.0601 |
Mycobacterium ulcerans | thymidylate synthase | 0.0105 | 0.1161 | 0.2086 |
Brugia malayi | 6-phosphofructokinase | 0.0105 | 0.1168 | 0.21 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0017 | 0.0014 | 0.001 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0105 | 0.1168 | 1 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0017 | 0.0014 | 0.001 |
Mycobacterium leprae | PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) | 0.0105 | 0.1168 | 0.1579 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | Serotonin receptor | 0.0017 | 0.0014 | 0.0018 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0105 | 0.1168 | 1 |
Toxoplasma gondii | ABC1 family protein | 0.0042 | 0.0347 | 0.0814 |
Brugia malayi | Melatonin receptor type 1A | 0.0017 | 0.0014 | 0.0018 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0042 | 0.0347 | 0.0343 |
Brugia malayi | orotate phosphoribosyltransferase family protein | 0.0062 | 0.0607 | 0.1088 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | orotidine 5'-phosphate decarboxylase | 0.0062 | 0.0607 | 0.0604 |
Schistosoma mansoni | opsin-like receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 0.0734 | 0.073 |
Trypanosoma cruzi | orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative | 0.0062 | 0.0607 | 0.1432 |
Mycobacterium tuberculosis | Hypothetical protein | 0.005 | 0.0446 | 0.0797 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0017 | 0.0014 | 0.001 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.034 | 0.4218 | 1 |
Echinococcus multilocularis | allatostatin A receptor | 0.0017 | 0.0014 | 0.001 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.034 | 0.4218 | 1 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0042 | 0.0347 | 0.0619 |
Echinococcus granulosus | tar DNA binding protein | 0.0072 | 0.0734 | 0.073 |
Echinococcus multilocularis | fmrfamide receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0017 | 0.0014 | 0.001 |
Onchocerca volvulus | 0.0042 | 0.0347 | 0.0467 | |
Brugia malayi | beta-lactamase family protein | 0.0042 | 0.0347 | 0.0619 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0057 | 0.0534 | 0.0956 |
Onchocerca volvulus | 0.0042 | 0.0347 | 0.0467 | |
Echinococcus granulosus | sex peptide receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0014 | 0.0018 |
Echinococcus multilocularis | fmrfamide receptor | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0072 | 0.0734 | 0.1316 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0042 | 0.0347 | 0.0619 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | neuropeptide receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | amine GPCR | 0.0017 | 0.0014 | 0.001 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0105 | 0.1168 | 1 |
Brugia malayi | Serotonin receptor | 0.0017 | 0.0014 | 0.0018 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0018 | 0.003 | 0.0048 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0017 | 0.0014 | 0.001 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0028 | 0.0168 | 0.1406 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0042 | 0.0347 | 0.0619 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0014 | 0.0018 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0105 | 0.1168 | 1 |
Mycobacterium leprae | DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) | 0.0442 | 0.5549 | 1 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0046 | 0.0394 | 0.0686 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0105 | 0.1168 | 1 |
Schistosoma mansoni | amine GPCR | 0.0017 | 0.0014 | 0.001 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0042 | 0.0347 | 0.0619 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0017 | 0.0014 | 0.0018 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0014 | 0.0018 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0028 | 0.0168 | 0.0295 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0105 | 0.1158 | 0.2081 |
Brugia malayi | G protein-coupled receptor | 0.0017 | 0.0014 | 0.0018 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0042 | 0.0347 | 0.0619 |
Plasmodium falciparum | glutathione reductase | 0.0046 | 0.0394 | 0.0925 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0016 | 0.0004 | 0.0005 |
Trichomonas vaginalis | esterase, putative | 0.0042 | 0.0347 | 0.2946 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0014 | 0.0018 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0017 | 0.0014 | 0.0018 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0105 | 0.1168 | 0.1165 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | hypothetical protein | 0.0017 | 0.0014 | 0.001 |
Plasmodium vivax | glutathione reductase, putative | 0.0046 | 0.0394 | 0.0925 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0017 | 0.0014 | 0.001 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0347 | 0.0601 |
Brugia malayi | ORL1-like opioid receptor | 0.0017 | 0.0014 | 0.0018 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0042 | 0.0347 | 0.0619 |
Echinococcus granulosus | g protein coupled receptor | 0.0017 | 0.0014 | 0.001 |
Mycobacterium tuberculosis | Conserved protein | 0.0042 | 0.0347 | 0.0619 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0016 | 0.0004 | 0.0005 |
Loa Loa (eye worm) | TAR-binding protein | 0.0072 | 0.0734 | 0.13 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0017 | 0.0014 | 0.0018 |
Brugia malayi | hypothetical protein | 0.0083 | 0.0878 | 0.1577 |
Brugia malayi | putative neuropeptide receptor | 0.0017 | 0.0014 | 0.0018 |
Echinococcus granulosus | g protein coupled receptor | 0.0017 | 0.0014 | 0.001 |
Trypanosoma cruzi | orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative | 0.0062 | 0.0607 | 0.1432 |
Onchocerca volvulus | 0.0105 | 0.1161 | 0.1609 | |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | TAR-binding protein | 0.0072 | 0.0734 | 0.1316 |
Echinococcus granulosus | thymidylate synthase | 0.0105 | 0.1161 | 0.1157 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0534 | 0.094 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0017 | 0.0014 | 0.001 |
Toxoplasma gondii | O-linked N-acetylglucosamine transferase | 0.0039 | 0.031 | 0.0727 |
Brugia malayi | Dopamine receptor protein 1 | 0.0017 | 0.0014 | 0.0018 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0042 | 0.0347 | 0.2946 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0046 | 0.0394 | 0.0703 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.003 | 0.0027 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0105 | 0.1168 | 1 |
Onchocerca volvulus | 0.0564 | 0.7138 | 1 | |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.0028 | 0.0168 | 0.0388 |
Entamoeba histolytica | hypothetical protein | 0.0083 | 0.0878 | 0.7104 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | serotonin receptor | 0.0017 | 0.0014 | 0.001 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0042 | 0.0347 | 0.0619 |
Leishmania major | hypothetical protein, conserved | 0.0042 | 0.0347 | 0.0814 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0116 | 0.1309 | 0.185 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0017 | 0.0014 | 0.001 |
Mycobacterium ulcerans | 6-phosphofructokinase | 0.0105 | 0.1168 | 0.21 |
Echinococcus multilocularis | tar DNA binding protein | 0.0072 | 0.0734 | 0.073 |
Giardia lamblia | O-linked GlcNAc transferase | 0.0023 | 0.0097 | 0.3055 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0017 | 0.0014 | 0.001 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0042 | 0.0347 | 0.2946 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0017 | 0.0014 | 0.0018 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0057 | 0.0534 | 0.0956 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | sex peptide receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | serotonin receptor | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | Dopamine receptor | 0.0017 | 0.0014 | 0.0018 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | thymidylate synthase | 0.0105 | 0.1161 | 0.1157 |
Loa Loa (eye worm) | hypothetical protein | 0.0264 | 0.3227 | 0.5806 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | neuropeptide receptor | 0.0017 | 0.0014 | 0.001 |
Mycobacterium leprae | Probable orotidine 5'-phosphate decarboxylase PyrF (OMP decarboxylase) (OMPDCase) (OMPdecase) | 0.0062 | 0.0607 | 0.0501 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 0.0734 | 0.073 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0017 | 0.0014 | 0.001 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0072 | 0.0734 | 0.13 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Plasmodium vivax | orotidine 5'-phosphate decarboxylase, putative | 0.0062 | 0.0607 | 0.1432 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | g protein coupled receptor | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0017 | 0.0014 | 0.0018 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0042 | 0.0347 | 0.0814 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0301 | 0.0519 |
Schistosoma mansoni | dihydrofolate reductase | 0.0442 | 0.5549 | 0.5547 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | hypothetical protein | 0.0083 | 0.0878 | 0.0875 |
Brugia malayi | hypothetical protein | 0.005 | 0.0446 | 0.0797 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.027 | 0.3309 | 0.5961 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0039 | 0.0301 | 0.0536 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0347 | 0.0601 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | fmrfamide receptor | 0.0017 | 0.0014 | 0.001 |
Mycobacterium tuberculosis | Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) | 0.0442 | 0.5549 | 1 |
Loa Loa (eye worm) | dihydrofolate reductase | 0.0442 | 0.5549 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.0028 | 0.0168 | 0.0388 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0017 | 0.0014 | 0.001 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0028 | 0.0168 | 0.1406 |
Mycobacterium tuberculosis | Conserved protein | 0.0042 | 0.0347 | 0.0619 |
Brugia malayi | thymidylate synthase | 0.0105 | 0.1161 | 0.2086 |
Mycobacterium tuberculosis | Conserved protein | 0.0042 | 0.0347 | 0.0619 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0083 | 0.0878 | 0.0875 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.034 | 0.4218 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0018 | 0.003 | 0.0027 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.003 | 0.0027 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0017 | 0.0014 | 0.0018 |
Echinococcus granulosus | serotonin receptor | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | neuropeptide receptor | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | G-protein coupled receptor | 0.0017 | 0.0014 | 0.0018 |
Schistosoma mansoni | biogenic amine receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.003 | 0.0027 |
Leishmania major | trypanothione reductase | 0.0046 | 0.0394 | 0.0925 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.0105 | 0.1161 | 0.2086 |
Entamoeba histolytica | hypothetical protein | 0.0083 | 0.0878 | 0.7104 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 0.0734 | 0.073 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0105 | 0.1158 | 0.2081 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | RE15519p | 0.0017 | 0.0014 | 0.0018 |
Brugia malayi | G-protein coupled receptor | 0.0017 | 0.0014 | 0.0018 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0017 | 0.0014 | 0.001 |
Leishmania major | ATP-dependent phosphofructokinase | 0.0105 | 0.1168 | 0.2763 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0028 | 0.0168 | 0.1406 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0014 | 0.0018 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0105 | 0.1168 | 0.1165 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.034 | 0.4218 | 1 |
Trypanosoma brucei | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0105 | 0.1168 | 0.2763 |
Brugia malayi | Thioredoxin reductase | 0.0046 | 0.0394 | 0.0703 |
Schistosoma mansoni | biogenic amine receptor | 0.0017 | 0.0014 | 0.001 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.034 | 0.4218 | 1 |
Echinococcus granulosus | neuropeptide receptor | 0.0017 | 0.0014 | 0.001 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0017 | 0.0014 | 0.001 |
Echinococcus multilocularis | dihydrofolate reductase | 0.0442 | 0.5549 | 0.5547 |
Mycobacterium leprae | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) | 0.0105 | 0.1161 | 0.1564 |
Schistosoma mansoni | tar DNA-binding protein | 0.0072 | 0.0734 | 0.073 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | Dihydrofolate reductase | 0.0442 | 0.5549 | 1 |
Mycobacterium ulcerans | dihydrofolate reductase DfrA | 0.0442 | 0.5549 | 1 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | RNA binding protein | 0.0072 | 0.0734 | 0.1316 |
Schistosoma mansoni | amine GPCR | 0.0017 | 0.0014 | 0.001 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | dihydrofolate reductase family protein | 0.0442 | 0.5549 | 1 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0105 | 0.1158 | 0.1558 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0017 | 0.0014 | 0.001 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0105 | 0.1158 | 0.2081 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0046 | 0.0394 | 0.039 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0017 | 0.0014 | 0.001 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0014 | 0.0018 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
PC50 (functional) | = 4.71 uM | Cytotoxicity against human PANC1 cells assessed as cell viability after 3 hrs by WST-8 cells | ChEMBL. | 23287053 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.