Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | guanylate cyclase, putative | 0.0362 | 0.0692 | 0.0795 |
Mycobacterium ulcerans | hypothetical protein | 0.052 | 0.1066 | 1 |
Leishmania major | cyclic nucleotide-binding protein-like protein | 0.052 | 0.1066 | 1 |
Schistosoma mansoni | high voltage-activated calcium channel Cav1 | 0.0259 | 0.045 | 0.0435 |
Onchocerca volvulus | Transient receptor potential cation channel trpm homolog | 0.0259 | 0.045 | 0.4131 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0362 | 0.0692 | 0.0795 |
Schistosoma mansoni | 60S ribosomal protein L21 | 0.0621 | 0.1305 | 0.1291 |
Loa Loa (eye worm) | hypothetical protein | 0.0259 | 0.045 | 0.0476 |
Plasmodium vivax | rap guanine nucleotide exchange factor, putative | 0.052 | 0.1066 | 1 |
Echinococcus granulosus | voltage gated sodium channel Nav1 alpha subunit | 0.0259 | 0.045 | 0.0476 |
Leishmania major | hypothetical protein, unknown function | 0.0259 | 0.045 | 0.4131 |
Treponema pallidum | catabolite gene activator | 0.052 | 0.1066 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0362 | 0.0692 | 0.0678 |
Echinococcus granulosus | potassium voltage gated channel protein | 0.0259 | 0.045 | 0.0476 |
Echinococcus multilocularis | cyclic nucleotide gated cation channel | 0.078 | 0.1679 | 0.1822 |
Trichomonas vaginalis | soluble guanylate cyclase gcy, putative | 0.0362 | 0.0692 | 0.0795 |
Loa Loa (eye worm) | hypothetical protein | 0.0259 | 0.045 | 0.0476 |
Brugia malayi | olfactory channel protein osm-9 | 0.0259 | 0.045 | 0.0476 |
Echinococcus multilocularis | TRP (transient receptor potential) channel | 0.0259 | 0.045 | 0.0476 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.052 | 0.1066 | 1 |
Echinococcus granulosus | potassium voltage gated channel protein | 0.0259 | 0.045 | 0.0476 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0362 | 0.0692 | 0.0795 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0362 | 0.0692 | 0.0795 |
Plasmodium vivax | CAMP-dependent protein kinase regulatory subunit, putative | 0.052 | 0.1066 | 1 |
Brugia malayi | Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog | 0.0259 | 0.045 | 0.0476 |
Onchocerca volvulus | 0.052 | 0.1066 | 1 | |
Echinococcus multilocularis | potassium voltage gated channel protein | 0.0259 | 0.045 | 0.0476 |
Brugia malayi | Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog | 0.0259 | 0.045 | 0.0476 |
Echinococcus granulosus | potassium voltage gated channel subfamily A | 0.0259 | 0.045 | 0.0476 |
Echinococcus granulosus | hyperpolarization activated cyclic | 0.078 | 0.1679 | 0.1822 |
Echinococcus granulosus | calcium activated potassium channel | 0.0259 | 0.045 | 0.0476 |
Brugia malayi | Hypothetical UPF0028 protein ZK370.4 in chromosome III, putative | 0.052 | 0.1066 | 0.1151 |
Loa Loa (eye worm) | hypothetical protein | 0.0259 | 0.045 | 0.0476 |
Echinococcus granulosus | sodium channel protein | 0.0259 | 0.045 | 0.0476 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0259 | 0.045 | 0.0476 |
Schistosoma mansoni | camp-dependent rap1 guanine-nucleotide exchange factor | 0.052 | 0.1066 | 0.1053 |
Plasmodium vivax | DNA gyrase subunit B, putative | 0.0136 | 0.0159 | 0.1366 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.3941 | 0.9145 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0362 | 0.0692 | 0.0795 |
Echinococcus multilocularis | patatin phospholipase domain containing protein | 0.052 | 0.1066 | 0.1151 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0259 | 0.045 | 0.0435 |
Schistosoma mansoni | high voltage-activated calcium channel Cav2A | 0.0259 | 0.045 | 0.0435 |
Echinococcus multilocularis | shaker cognate | 0.0259 | 0.045 | 0.0476 |
Trichomonas vaginalis | cAMP-dependent protein kinase type I-beta regulatory subunit, putative | 0.052 | 0.1066 | 0.1234 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0259 | 0.045 | 0.0476 |
Loa Loa (eye worm) | calcium channel | 0.0259 | 0.045 | 0.0476 |
Treponema pallidum | cyclic nucleotide binding protein | 0.052 | 0.1066 | 1 |
Schistosoma mansoni | neuropathy target esterase/swiss cheese-related protein | 0.052 | 0.1066 | 0.1053 |
Brugia malayi | ion channel NompC | 0.0259 | 0.045 | 0.0476 |
Toxoplasma gondii | cyclic nucleotide-binding domain-containing protein | 0.052 | 0.1066 | 1 |
Echinococcus granulosus | voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 | 0.0259 | 0.045 | 0.0476 |
Echinococcus multilocularis | cGMP dependent protein kinase 1 | 0.052 | 0.1066 | 0.1151 |
Trichomonas vaginalis | adenylate cyclase type IX, putative | 0.0362 | 0.0692 | 0.0795 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0362 | 0.0692 | 0.0795 |
Echinococcus multilocularis | voltage gated potassium channel | 0.1142 | 0.2534 | 0.2758 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.052 | 0.1066 | 0.1234 |
Mycobacterium ulcerans | transcriptional regulatory protein | 0.052 | 0.1066 | 1 |
Loa Loa (eye worm) | voltage-gated potassium channel | 0.0259 | 0.045 | 0.0476 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0259 | 0.045 | 0.0435 |
Echinococcus granulosus | potassium large conductance calcium activated | 0.0259 | 0.045 | 0.0476 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0362 | 0.0692 | 0.0795 |
Trichomonas vaginalis | adenylate cyclase type III, putative | 0.0362 | 0.0692 | 0.0795 |
Onchocerca volvulus | 0.052 | 0.1066 | 1 | |
Schistosoma mansoni | voltage-gated ion channel | 0.0259 | 0.045 | 0.0435 |
Echinococcus multilocularis | expressed conserved protein | 0.052 | 0.1066 | 0.1151 |
Brugia malayi | Egg laying defective protein 4 | 0.052 | 0.1066 | 0.1151 |
Echinococcus multilocularis | conserved hypothetical protein | 0.0259 | 0.045 | 0.0476 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0259 | 0.045 | 0.0435 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0362 | 0.0692 | 0.0795 |
Schistosoma mansoni | transient receptor potential channel | 0.0259 | 0.045 | 0.0435 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0362 | 0.0692 | 0.0795 |
Schistosoma mansoni | voltage-dependent calcium channel | 0.0259 | 0.045 | 0.0435 |
Echinococcus granulosus | cyclic nucleotide gated cation channel | 0.078 | 0.1679 | 0.1822 |
Loa Loa (eye worm) | hypothetical protein | 0.0259 | 0.045 | 0.0476 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0362 | 0.0692 | 0.0795 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0362 | 0.0692 | 0.0795 |
Brugia malayi | Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog | 0.0259 | 0.045 | 0.0476 |
Loa Loa (eye worm) | hypothetical protein | 0.0259 | 0.045 | 0.0476 |
Echinococcus multilocularis | cAMP dependent protein kinase type II regulatory | 0.052 | 0.1066 | 0.1151 |
Brugia malayi | Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog | 0.0259 | 0.045 | 0.0476 |
Brugia malayi | Ryanodine Receptor TM 4-6 family protein | 0.0259 | 0.045 | 0.0476 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0362 | 0.0692 | 0.0795 |
Trypanosoma brucei | Voltage-dependent calcium channel subunit, putative | 0.0259 | 0.045 | 0.4131 |
Wolbachia endosymbiont of Brugia malayi | DNA gyrase subunit A | 0.0259 | 0.0449 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0362 | 0.0692 | 0.0795 |
Loa Loa (eye worm) | hypothetical protein | 0.052 | 0.1066 | 0.1151 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.1142 | 0.2534 | 0.2758 |
Plasmodium falciparum | cAMP-dependent protein kinase regulatory subunit | 0.052 | 0.1066 | 1 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0259 | 0.045 | 0.0435 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0362 | 0.0692 | 0.0795 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0362 | 0.0692 | 0.0795 |
Echinococcus multilocularis | cAMP dependent protein kinase regulatory | 0.052 | 0.1066 | 0.1151 |
Echinococcus multilocularis | voltage gated potassium channel | 0.0259 | 0.045 | 0.0476 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0362 | 0.0692 | 0.0795 |
Loa Loa (eye worm) | hypothetical protein | 0.0259 | 0.045 | 0.0476 |
Schistosoma mansoni | camp-dependent protein kinase type II-alpha regulatory subunit | 0.052 | 0.1066 | 0.1053 |
Loa Loa (eye worm) | hypothetical protein | 0.342 | 0.7916 | 0.8654 |
Loa Loa (eye worm) | cyclic-nucleotide gated cation channel | 0.078 | 0.1679 | 0.1822 |
Echinococcus granulosus | potassium voltage gated channel protein | 0.0259 | 0.045 | 0.0476 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.3941 | 0.9145 | 1 |
Leishmania major | protein kinase, putative | 0.052 | 0.1066 | 1 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0362 | 0.0692 | 0.0795 |
Chlamydia trachomatis | DNA gyrase subunit A | 0.0259 | 0.0449 | 0.3201 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0259 | 0.045 | 0.4131 |
Trypanosoma brucei | inositol 1,4,5-trisphosphate receptor | 0.0259 | 0.045 | 0.4131 |
Echinococcus granulosus | potassium voltage gated channel subfamily D | 0.0259 | 0.045 | 0.0476 |
Brugia malayi | Voltage-gated calcium channel, alpha subunit | 0.0259 | 0.045 | 0.0476 |
Schistosoma mansoni | voltage-gated potassium channel | 0.078 | 0.1679 | 0.1666 |
Echinococcus multilocularis | potassium voltage gated channel subfamily D | 0.0259 | 0.045 | 0.0476 |
Echinococcus granulosus | shaker cognate | 0.0259 | 0.045 | 0.0476 |
Trichomonas vaginalis | adenylate cyclase type IX, putative | 0.0362 | 0.0692 | 0.0795 |
Trypanosoma brucei | cyclic nucleotide-binding domain containing protein, putative | 0.052 | 0.1066 | 1 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.0259 | 0.045 | 0.0435 |
Echinococcus multilocularis | potassium voltage gated channel protein | 0.0259 | 0.045 | 0.0476 |
Brugia malayi | N-terminal motif family protein | 0.052 | 0.1066 | 0.1151 |
Mycobacterium tuberculosis | Probable glutamine-transport ATP-binding protein ABC transporter GlnQ | 0.052 | 0.1066 | 1 |
Plasmodium falciparum | DNA gyrase subunit A | 0.0259 | 0.0449 | 0.413 |
Echinococcus multilocularis | potassium voltage gated channel subfamily D | 0.0259 | 0.045 | 0.0476 |
Trichomonas vaginalis | adenylate cyclase type VI, putative | 0.0362 | 0.0692 | 0.0795 |
Echinococcus multilocularis | transfer RNA-Gly | 0.0259 | 0.045 | 0.0476 |
Schistosoma mansoni | hyperpolarization activated cyclic nucleotide-gated potassium channel | 0.0259 | 0.045 | 0.0435 |
Loa Loa (eye worm) | hypothetical protein | 0.0259 | 0.045 | 0.0476 |
Toxoplasma gondii | cyclic nucleotide-binding domain-containing protein | 0.052 | 0.1066 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.052 | 0.1066 | 1 |
Mycobacterium tuberculosis | Probable conserved transmembrane transport protein | 0.052 | 0.1066 | 1 |
Echinococcus granulosus | cyclic nucleotide gated cation channel | 0.078 | 0.1679 | 0.1822 |
Echinococcus multilocularis | potassium voltage gated channel subfamily KQT | 0.0259 | 0.045 | 0.0476 |
Brugia malayi | Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit | 0.0259 | 0.045 | 0.0476 |
Brugia malayi | Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit | 0.0259 | 0.045 | 0.0476 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.078 | 0.1679 | 0.1666 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0362 | 0.0692 | 0.0795 |
Trypanosoma cruzi | cAMP response protein 1, putative | 0.052 | 0.1066 | 1 |
Schistosoma mansoni | camp-dependent protein kinase type I-beta regulatory subunit | 0.052 | 0.1066 | 0.1053 |
Echinococcus granulosus | voltage gated hydrogen channel 1 | 0.0259 | 0.045 | 0.0476 |
Echinococcus multilocularis | sodium channel protein | 0.0259 | 0.045 | 0.0476 |
Trichomonas vaginalis | cAMP-dependent protein kinase regulatory subunit, putative | 0.052 | 0.1066 | 0.1234 |
Echinococcus granulosus | potassium voltage gated channel subfamily D | 0.0259 | 0.045 | 0.0476 |
Toxoplasma gondii | protein kinase G AGC kinase family member PKG | 0.052 | 0.1066 | 1 |
Mycobacterium tuberculosis | DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) | 0.0259 | 0.0449 | 0.3201 |
Leishmania major | calcium channel protein, putative,ion transporter, putative | 0.0259 | 0.045 | 0.4131 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0362 | 0.0692 | 0.0795 |
Toxoplasma gondii | cyclic nucleotide-binding domain-containing protein | 0.052 | 0.1066 | 1 |
Trichomonas vaginalis | guanylate cyclase beta 1 subunit, putative | 0.0362 | 0.0692 | 0.0795 |
Loa Loa (eye worm) | cyclic-nucleotide gated cation channel | 0.078 | 0.1679 | 0.1822 |
Schistosoma mansoni | two-pore calcium channel | 0.0259 | 0.045 | 0.0435 |
Loa Loa (eye worm) | hypothetical protein | 0.0259 | 0.045 | 0.0476 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0362 | 0.0692 | 0.0795 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0362 | 0.0692 | 0.0795 |
Brugia malayi | Transient-receptor-potential like protein | 0.0259 | 0.045 | 0.0476 |
Echinococcus multilocularis | two pore calcium channel protein 1 | 0.0259 | 0.045 | 0.0476 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0362 | 0.0692 | 0.0795 |
Echinococcus granulosus | cyclic nucleotide gated cation channel alpha 3 | 0.078 | 0.1679 | 0.1822 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0259 | 0.045 | 0.0476 |
Treponema pallidum | cyclic nucleotide binding protein | 0.052 | 0.1066 | 1 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0259 | 0.045 | 0.0476 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0362 | 0.0692 | 0.0795 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0362 | 0.0692 | 0.0795 |
Echinococcus granulosus | patatin phospholipase domain containing protein | 0.052 | 0.1066 | 0.1151 |
Trichomonas vaginalis | adenylate cyclase type III, putative | 0.0362 | 0.0692 | 0.0795 |
Leishmania major | hypothetical protein, conserved | 0.052 | 0.1066 | 1 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.3941 | 0.9145 | 1 |
Echinococcus granulosus | short transient receptor potential channel 6 | 0.0259 | 0.045 | 0.0476 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0362 | 0.0692 | 0.0795 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0362 | 0.0692 | 0.0795 |
Trichomonas vaginalis | soluble guanylate cyclase gcy, putative | 0.0362 | 0.0692 | 0.0795 |
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.0259 | 0.045 | 0.0476 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0362 | 0.0692 | 0.0795 |
Echinococcus granulosus | potassium voltage gated channel protein | 0.0259 | 0.045 | 0.0476 |
Leishmania major | protein kinase A regulatory subunit, putative | 0.052 | 0.1066 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0259 | 0.045 | 0.0476 |
Loa Loa (eye worm) | AGC/PKG protein kinase | 0.052 | 0.1066 | 0.1151 |
Schistosoma mansoni | cyclic nucleotide-gated ion channel | 0.052 | 0.1066 | 0.1053 |
Loa Loa (eye worm) | ryanodine receptor | 0.0259 | 0.045 | 0.0476 |
Mycobacterium ulcerans | hypothetical protein | 0.052 | 0.1066 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0259 | 0.045 | 0.4131 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.078 | 0.1679 | 0.1953 |
Schistosoma mansoni | calcium-activated potassium channel | 0.0259 | 0.045 | 0.0435 |
Trypanosoma cruzi | regulatory subunit of protein kinase a-like protein, putative | 0.052 | 0.1066 | 1 |
Leishmania major | regulatory subunit of protein kinase a-like protein | 0.052 | 0.1066 | 1 |
Echinococcus multilocularis | hyperpolarization activated cyclic | 0.078 | 0.1679 | 0.1822 |
Leishmania major | hypothetical protein, unknown function | 0.052 | 0.1066 | 1 |
Echinococcus multilocularis | cyclic nucleotide gated cation channel alpha 3 | 0.078 | 0.1679 | 0.1822 |
Echinococcus multilocularis | voltage dependent calcium channel type d subunit | 0.0259 | 0.045 | 0.0476 |
Entamoeba histolytica | DNA topoisomerase II, putative | 0.0075 | 0.0015 | 0.5 |
Trypanosoma brucei | cAMP response protein 1, putative | 0.052 | 0.1066 | 1 |
Echinococcus granulosus | single minded 2 | 0.0362 | 0.0692 | 0.0741 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0259 | 0.045 | 0.0435 |
Loa Loa (eye worm) | hypothetical protein | 0.052 | 0.1066 | 0.1151 |
Schistosoma mansoni | voltage-gated cation channel | 0.0259 | 0.045 | 0.0435 |
Loa Loa (eye worm) | hypothetical protein | 0.0259 | 0.045 | 0.0476 |
Echinococcus multilocularis | voltage dependent calcium channel | 0.0259 | 0.045 | 0.0476 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0362 | 0.0692 | 0.0795 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0362 | 0.0692 | 0.0795 |
Echinococcus granulosus | cAMP dependent protein kinase type I beta | 0.052 | 0.1066 | 0.1151 |
Toxoplasma gondii | cAMP-dependent protein kinase regulatory subunit | 0.052 | 0.1066 | 1 |
Treponema pallidum | catabolite gene activator (Crp) | 0.052 | 0.1066 | 1 |
Echinococcus granulosus | voltage dependent calcium channel | 0.0259 | 0.045 | 0.0476 |
Loa Loa (eye worm) | ion channel NompC | 0.0259 | 0.045 | 0.0476 |
Schistosoma mansoni | voltage-gated potassium channel | 0.1142 | 0.2534 | 0.2522 |
Toxoplasma gondii | hypothetical protein | 0.0259 | 0.045 | 0.4131 |
Echinococcus granulosus | sodium leak channel non selective protein | 0.0259 | 0.045 | 0.0476 |
Toxoplasma gondii | DNA gyrase/topoisomerase IV, A subunit domain-containing protein | 0.0259 | 0.0449 | 0.413 |
Trichomonas vaginalis | soluble guanylate cyclase gcy, putative | 0.0362 | 0.0692 | 0.0795 |
Schistosoma mansoni | camp-dependent protein kinase type I-beta regulatory subunit | 0.052 | 0.1066 | 0.1053 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0362 | 0.0692 | 0.0795 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.3681 | 0.8533 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.052 | 0.1066 | 0.1234 |
Trypanosoma brucei | STE group serine/threonine-protein kinase, putative | 0.0362 | 0.0692 | 0.644 |
Trichomonas vaginalis | adenylate cyclase type, putative | 0.0362 | 0.0692 | 0.0795 |
Echinococcus granulosus | cGMP dependent protein kinase 1 | 0.052 | 0.1066 | 0.1151 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0362 | 0.0692 | 0.0795 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.078 | 0.1679 | 0.1666 |
Echinococcus multilocularis | voltage gated hydrogen channel 1 | 0.0259 | 0.045 | 0.0476 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0259 | 0.045 | 0.0476 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.052 | 0.1066 | 0.1234 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0362 | 0.0692 | 0.0795 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0362 | 0.0692 | 0.0795 |
Brugia malayi | Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog | 0.1142 | 0.2534 | 0.2758 |
Echinococcus granulosus | hyperpolarization activated cyclic | 0.078 | 0.1679 | 0.1822 |
Schistosoma mansoni | camp-dependent protein kinase regulatory chain | 0.052 | 0.1066 | 0.1053 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0362 | 0.0692 | 0.0795 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.052 | 0.1066 | 1 |
Leishmania major | hypothetical protein, conserved | 0.052 | 0.1066 | 1 |
Echinococcus multilocularis | calcium activated potassium channel | 0.0259 | 0.045 | 0.0476 |
Loa Loa (eye worm) | cAMP-dependent protein kinase regulatory subunit | 0.052 | 0.1066 | 0.1151 |
Trypanosoma brucei | cyclic nucleotide-binding domain containing protein, putative | 0.052 | 0.1066 | 1 |
Onchocerca volvulus | Transient receptor potential cation channel trpm homolog | 0.0259 | 0.045 | 0.4131 |
Loa Loa (eye worm) | hypothetical protein | 0.0259 | 0.045 | 0.0476 |
Trypanosoma cruzi | inositol 1,4,5-trisphosphate receptor, putative | 0.0259 | 0.045 | 0.4131 |
Echinococcus multilocularis | cyclic nucleotide gated cation channel | 0.052 | 0.1066 | 0.1151 |
Trypanosoma cruzi | cAMP response protein 1 | 0.052 | 0.1066 | 1 |
Trypanosoma brucei | Flagellar Member 6 | 0.052 | 0.1066 | 1 |
Brugia malayi | cation channel family protein | 0.0259 | 0.045 | 0.0476 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0362 | 0.0692 | 0.0795 |
Trypanosoma cruzi | Flagellar Member 6 | 0.052 | 0.1066 | 1 |
Brugia malayi | Cyclic-nucleotide gated cation channel, C. elegans tax-4 ortholog | 0.052 | 0.1066 | 0.1151 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0362 | 0.0692 | 0.0795 |
Echinococcus granulosus | voltage dependent calcium channel | 0.0259 | 0.045 | 0.0476 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0362 | 0.0692 | 0.0795 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0259 | 0.045 | 0.0435 |
Echinococcus multilocularis | voltage dependent L type calcium channel subunit | 0.0259 | 0.045 | 0.0476 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0362 | 0.0692 | 0.0795 |
Loa Loa (eye worm) | voltage-dependent calcium channel | 0.0259 | 0.045 | 0.0476 |
Mycobacterium tuberculosis | Conserved protein | 0.052 | 0.1066 | 1 |
Schistosoma mansoni | transient receptor potential cation channel subfamily m member | 0.0259 | 0.045 | 0.0435 |
Loa Loa (eye worm) | hypothetical protein | 0.1142 | 0.2534 | 0.2758 |
Echinococcus granulosus | cAMP dependent protein kinase regulatory | 0.052 | 0.1066 | 0.1151 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0259 | 0.045 | 0.4131 |
Trichomonas vaginalis | guanylate cyclase beta 2 subunit, putative | 0.0362 | 0.0692 | 0.0795 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0362 | 0.0692 | 0.0795 |
Trichomonas vaginalis | soluble guanylate cyclase gcy, putative | 0.0362 | 0.0692 | 0.0795 |
Toxoplasma gondii | hypothetical protein | 0.0259 | 0.045 | 0.4131 |
Loa Loa (eye worm) | voltage-gated potassium channel | 0.0259 | 0.045 | 0.0476 |
Echinococcus granulosus | potassium channel KvQLT family member kqt 1 | 0.0259 | 0.045 | 0.0476 |
Loa Loa (eye worm) | hypothetical protein | 0.0259 | 0.045 | 0.0476 |
Echinococcus multilocularis | cGMP dependent protein kinase 1 | 0.052 | 0.1066 | 0.1151 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.1142 | 0.2534 | 0.2758 |
Chlamydia trachomatis | cAMP-dependent protein kinase regulatory subunit | 0.052 | 0.1066 | 1 |
Giardia lamblia | CAMP-dependent protein kinase regulatory chain | 0.052 | 0.1066 | 1 |
Echinococcus granulosus | voltage gated potassium channel | 0.0259 | 0.045 | 0.0476 |
Brugia malayi | Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog | 0.0259 | 0.045 | 0.0476 |
Mycobacterium leprae | Possible transporter protein | 0.0362 | 0.0692 | 0.6008 |
Echinococcus granulosus | cyclic nucleotide gated cation channel | 0.052 | 0.1066 | 0.1151 |
Schistosoma mansoni | neuropathy target esterase/swiss cheese-related protein | 0.052 | 0.1066 | 0.1053 |
Echinococcus multilocularis | two pore calcium channel protein 2 | 0.0259 | 0.045 | 0.0476 |
Treponema pallidum | DNA gyrase, subunit A (gyrA) | 0.0259 | 0.0449 | 0.3201 |
Echinococcus multilocularis | voltage dependent L type calcium channel subunit | 0.0259 | 0.045 | 0.0476 |
Echinococcus multilocularis | potassium:sodium hyperpolarization activated | 0.078 | 0.1679 | 0.1822 |
Echinococcus granulosus | ryanodine receptor 44f | 0.0259 | 0.045 | 0.0476 |
Mycobacterium ulcerans | regulatory protein | 0.052 | 0.1066 | 1 |
Echinococcus granulosus | potassium voltage gated channel subfamily C | 0.0259 | 0.045 | 0.0476 |
Echinococcus multilocularis | potassium voltage gated channel subfamily A | 0.0259 | 0.045 | 0.0476 |
Mycobacterium ulcerans | DNA gyrase subunit A | 0.0259 | 0.0449 | 0.3201 |
Echinococcus multilocularis | voltage dependent calcium channel | 0.0259 | 0.045 | 0.0476 |
Trypanosoma cruzi | cAMP binding protein, putative | 0.052 | 0.1066 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.078 | 0.1679 | 0.1822 |
Trypanosoma brucei | protein kinase A regulatory subunit | 0.052 | 0.1066 | 1 |
Schistosoma mansoni | camp-dependent protein kinase type II regulatory subunit | 0.052 | 0.1066 | 0.1053 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0362 | 0.0692 | 0.0795 |
Schistosoma mansoni | voltage-gated potassium channel | 0.1142 | 0.2534 | 0.2522 |
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.0259 | 0.045 | 0.0476 |
Schistosoma mansoni | transient receptor potential channel 4 | 0.0259 | 0.045 | 0.0435 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0259 | 0.045 | 0.0476 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0362 | 0.0692 | 0.0795 |
Loa Loa (eye worm) | hypothetical protein | 0.0259 | 0.045 | 0.0476 |
Echinococcus granulosus | two pore calcium channel protein 2 | 0.0259 | 0.045 | 0.0476 |
Brugia malayi | Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit | 0.0259 | 0.045 | 0.0476 |
Trichomonas vaginalis | adenylate cyclase type vIII, putative | 0.0362 | 0.0692 | 0.0795 |
Toxoplasma gondii | transporter, cation channel family protein | 0.0259 | 0.045 | 0.4131 |
Brugia malayi | voltage-dependent calcium channel | 0.0259 | 0.045 | 0.0476 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0259 | 0.045 | 0.0435 |
Echinococcus multilocularis | sodium leak channel non selective protein | 0.0259 | 0.045 | 0.0476 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0259 | 0.045 | 0.0435 |
Echinococcus granulosus | potassium:sodium hyperpolarization activated | 0.078 | 0.1679 | 0.1822 |
Echinococcus granulosus | two pore calcium channel protein 1 | 0.0259 | 0.045 | 0.0476 |
Echinococcus multilocularis | potassium voltage gated channel subfamily C | 0.0259 | 0.045 | 0.0476 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.078 | 0.1679 | 0.1953 |
Echinococcus granulosus | TRP transient receptor potential channel | 0.0259 | 0.045 | 0.0476 |
Echinococcus granulosus | Potassium voltage gated channel protein Shaw | 0.0259 | 0.045 | 0.0476 |
Mycobacterium ulcerans | transmembrane transport protein | 0.052 | 0.1066 | 1 |
Plasmodium vivax | DNA gyrase subunit A, putative | 0.0259 | 0.0449 | 0.413 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.052 | 0.1066 | 0.1053 |
Brugia malayi | hypothetical protein | 0.0259 | 0.045 | 0.0476 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0259 | 0.045 | 0.0476 |
Schistosoma mansoni | similar to Protein C20orf152 homolog | 0.052 | 0.1066 | 0.1053 |
Mycobacterium tuberculosis | Probable conserved transmembrane protein | 0.052 | 0.1066 | 1 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0362 | 0.0692 | 0.0795 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0362 | 0.0692 | 0.0795 |
Brugia malayi | aryl hydrocarbon receptor nuclear translocator protein, putative | 0.0362 | 0.0692 | 0.0741 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.3941 | 0.9145 | 1 |
Schistosoma mansoni | hypothetical protein | 0.052 | 0.1066 | 0.1053 |
Echinococcus granulosus | cAMP dependent protein kinase type II regulatory | 0.052 | 0.1066 | 0.1151 |
Trichomonas vaginalis | adenylate cyclase type, putative | 0.0362 | 0.0692 | 0.0795 |
Echinococcus granulosus | voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu | 0.0259 | 0.045 | 0.0476 |
Echinococcus granulosus | hypothetical protein | 0.0259 | 0.045 | 0.0476 |
Brugia malayi | cation channel family protein | 0.0259 | 0.045 | 0.0476 |
Trypanosoma cruzi | cyclic nucleotide-binding domain containing protein, putative | 0.052 | 0.1066 | 1 |
Schistosoma mansoni | transient receptor potential channel | 0.0259 | 0.045 | 0.0435 |
Echinococcus granulosus | potassium voltage gated channel subfamily D | 0.0259 | 0.045 | 0.0476 |
Schistosoma mansoni | calcium channel voltage-dependent p/q type alpha 1a-related | 0.0259 | 0.045 | 0.0435 |
Echinococcus multilocularis | potassium large conductance calcium activated | 0.0259 | 0.045 | 0.0476 |
Echinococcus multilocularis | hyperpolarization activated cyclic | 0.078 | 0.1679 | 0.1822 |
Echinococcus multilocularis | voltage dependent calcium channel type d subunit | 0.0259 | 0.045 | 0.0476 |
Echinococcus multilocularis | cAMP dependent protein kinase type I beta | 0.052 | 0.1066 | 0.1151 |
Trypanosoma cruzi | regulatory subunit of protein kinase a-like protein, putative | 0.052 | 0.1066 | 1 |
Plasmodium falciparum | DNA gyrase subunit B | 0.0136 | 0.0159 | 0.1366 |
Schistosoma mansoni | transient receptor potential cation channel subfamily m member | 0.0259 | 0.045 | 0.0435 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0259 | 0.045 | 0.0476 |
Toxoplasma gondii | cyclic nucleotide-binding domain-containing protein | 0.052 | 0.1066 | 1 |
Schistosoma mansoni | inositol 145-trisphosphate receptor | 0.0259 | 0.045 | 0.0435 |
Loa Loa (eye worm) | hypothetical protein | 0.0259 | 0.045 | 0.0476 |
Toxoplasma gondii | transporter, cation channel family protein | 0.0259 | 0.045 | 0.4131 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0259 | 0.045 | 0.0476 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0621 | 0.1305 | 0.1291 |
Trichomonas vaginalis | adenylate cyclase type IX, putative | 0.0362 | 0.0692 | 0.0795 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0362 | 0.0692 | 0.0795 |
Echinococcus multilocularis | potassium voltage gated channel protein | 0.0259 | 0.045 | 0.0476 |
Schistosoma mansoni | serine/threonine protein kinase | 0.052 | 0.1066 | 0.1053 |
Brugia malayi | Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog | 0.0259 | 0.045 | 0.0476 |
Plasmodium falciparum | cGMP-dependent protein kinase | 0.052 | 0.1066 | 1 |
Trichomonas vaginalis | adenylate cyclase type, putative | 0.0362 | 0.0692 | 0.0795 |
Schistosoma mansoni | serine/threonine protein kinase | 0.052 | 0.1066 | 0.1053 |
Toxoplasma gondii | transporter, cation channel family protein | 0.0259 | 0.045 | 0.4131 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0259 | 0.045 | 0.0476 |
Brugia malayi | Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog | 0.0259 | 0.045 | 0.0476 |
Schistosoma mansoni | transient receptor potential cation channel subfamily m member | 0.0259 | 0.045 | 0.0435 |
Trichomonas vaginalis | adenylate cyclase type IX, putative | 0.0362 | 0.0692 | 0.0795 |
Trichomonas vaginalis | adenylyl cyclase type V, putative | 0.0362 | 0.0692 | 0.0795 |
Leishmania major | hypothetical protein, conserved | 0.052 | 0.1066 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0259 | 0.045 | 0.0476 |
Schistosoma mansoni | transient receptor potential channel | 0.0259 | 0.045 | 0.0435 |
Schistosoma mansoni | vesicular amine transporter | 0.0259 | 0.045 | 0.0435 |
Schistosoma mansoni | hypothetical protein | 0.0259 | 0.045 | 0.0435 |
Echinococcus granulosus | cGMP dependent protein kinase | 0.052 | 0.1066 | 0.1151 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0259 | 0.045 | 0.0435 |
Mycobacterium ulcerans | hypothetical protein | 0.052 | 0.1066 | 1 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0259 | 0.045 | 0.0476 |
Brugia malayi | cAMP-dependent protein kinase regulatory chain, putative | 0.052 | 0.1066 | 0.1151 |
Loa Loa (eye worm) | hypothetical protein | 0.0259 | 0.045 | 0.0476 |
Schistosoma mansoni | serine/threonine protein kinase | 0.052 | 0.1066 | 0.1053 |
Echinococcus granulosus | short transient receptor potential channel 6 | 0.0259 | 0.045 | 0.0476 |
Trypanosoma brucei | cAMP binding protein, putative | 0.052 | 0.1066 | 1 |
Echinococcus multilocularis | potassium voltage gated channel subfamily D | 0.0259 | 0.045 | 0.0476 |
Echinococcus multilocularis | potassium voltage gated channel protein | 0.0259 | 0.045 | 0.0476 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0362 | 0.0692 | 0.0795 |
Mycobacterium ulcerans | hypothetical protein | 0.052 | 0.1066 | 1 |
Brugia malayi | Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit | 0.0259 | 0.045 | 0.0476 |
Schistosoma mansoni | hyperpolarization activated cyclic nucleotide-gated potassium channel | 0.052 | 0.1066 | 0.1053 |
Trypanosoma cruzi | Voltage-dependent calcium channel subunit, putative | 0.0259 | 0.045 | 0.4131 |
Loa Loa (eye worm) | hypothetical protein | 0.0259 | 0.045 | 0.0476 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0362 | 0.0692 | 0.0795 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.078 | 0.1679 | 0.1666 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0259 | 0.045 | 0.0476 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.052 | 0.1066 | 1 |
Mycobacterium tuberculosis | Probable transcriptional regulatory protein Cmr | 0.052 | 0.1066 | 1 |
Leishmania major | protein kinase, putative | 0.052 | 0.1066 | 1 |
Echinococcus granulosus | voltage gated potassium channel | 0.1142 | 0.2534 | 0.2758 |
Trichomonas vaginalis | soluble guanylate cyclase gcy, putative | 0.0362 | 0.0692 | 0.0795 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0362 | 0.0692 | 0.0795 |
Echinococcus multilocularis | cyclic nucleotide gated cation channel | 0.052 | 0.1066 | 0.1151 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.3681 | 0.8533 | 1 |
Schistosoma mansoni | hyperpolarization activated cyclic nucleotide-gated potassium channel | 0.078 | 0.1679 | 0.1666 |
Trichomonas vaginalis | intestinal guanylate cyclase, putative | 0.0362 | 0.0692 | 0.0795 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0259 | 0.045 | 0.0435 |
Loa Loa (eye worm) | voltage-gated calcium channel | 0.0259 | 0.045 | 0.0476 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0362 | 0.0692 | 0.0795 |
Echinococcus granulosus | transient receptor potential gamma protein | 0.0259 | 0.045 | 0.0476 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0259 | 0.045 | 0.0435 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0362 | 0.0692 | 0.0795 |
Trichomonas vaginalis | hypothetical protein | 0.0362 | 0.0692 | 0.0795 |
Brugia malayi | Cyclic-nucleotide gated cation channel | 0.078 | 0.1679 | 0.1822 |
Echinococcus multilocularis | ryanodine receptor 44f | 0.0259 | 0.045 | 0.0476 |
Schistosoma mansoni | transient receptor potential cation channel subfamily m member | 0.0259 | 0.045 | 0.0435 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0362 | 0.0692 | 0.0795 |
Echinococcus multilocularis | transient receptor potential gamma protein | 0.0259 | 0.045 | 0.0476 |
Loa Loa (eye worm) | hypothetical protein | 0.0259 | 0.045 | 0.0476 |
Schistosoma mansoni | ryanodine receptor related | 0.0259 | 0.045 | 0.0435 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0362 | 0.0692 | 0.0795 |
Schistosoma mansoni | voltage-gated potassium channel KCNQ | 0.0259 | 0.045 | 0.0435 |
Echinococcus granulosus | potassium voltage gated channel protein | 0.0259 | 0.045 | 0.0476 |
Onchocerca volvulus | 0.0259 | 0.045 | 0.4131 | |
Echinococcus granulosus | cGMP dependent protein kinase 1 | 0.052 | 0.1066 | 0.1151 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0259 | 0.045 | 0.0435 |
Mycobacterium leprae | Conserved hypothetical protein | 0.052 | 0.1066 | 1 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0362 | 0.0692 | 0.0795 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0362 | 0.0692 | 0.0795 |
Schistosoma mansoni | hyperpolarization activated cyclic nucleotide-gated potassium channel | 0.078 | 0.1679 | 0.1666 |
Echinococcus granulosus | voltage dependent L type calcium channel subunit|voltage dependent calcium channel | 0.0259 | 0.045 | 0.0476 |
Trypanosoma cruzi | protein kinase A regulatory subunit | 0.052 | 0.1066 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0259 | 0.045 | 0.0476 |
Schistosoma mansoni | transient receptor potential cation channel subfamily m member | 0.0259 | 0.045 | 0.0435 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | = 75 % | Cytoprotective activity against shiga toxin-induced cytotoxicity in human HeLa cells at 30 uM incubated for 4 hrs prior to shiga toxin addition measured after 20 hrs by liquid scintillation counting analysis relative to Retro-2 | ChEMBL. | 23517565 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.