Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | Cathepsin L homolog | 0.006 | 0.0139 | 0.0497 |
Loa Loa (eye worm) | hypothetical protein | 0.0724 | 0.401 | 1 |
Toxoplasma gondii | preprocathepsin c precursor, putative | 0.0264 | 0.1328 | 0.5939 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0185 | 0.0868 | 0.0788 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0326 | 0.1688 | 0.8952 |
Brugia malayi | cathepsin B-like cysteine proteinase | 0.0724 | 0.401 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0185 | 0.0868 | 0.4308 |
Leishmania major | cathepsin L-like protease | 0.0326 | 0.1688 | 0.9177 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0771 | 0.4289 | 0.4239 |
Plasmodium vivax | unspecified product | 0.006 | 0.0139 | 0.0962 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0185 | 0.0868 | 0.4308 |
Schistosoma mansoni | hypothetical protein | 0.0189 | 0.0894 | 0.2064 |
Leishmania major | cathepsin L-like protease | 0.0185 | 0.0868 | 0.4475 |
Echinococcus granulosus | tumor protein p63 | 0.0352 | 0.184 | 0.4172 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0724 | 0.401 | 0.9346 |
Brugia malayi | AMP-binding enzyme family protein | 0.0051 | 0.0088 | 0.0191 |
Echinococcus granulosus | cathepsin b | 0.0724 | 0.401 | 0.9334 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0051 | 0.0088 | 1 |
Schistosoma mansoni | survival motor neuron protein | 0.005 | 0.0082 | 0.0165 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0115 | 0.0462 | 0.4794 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0051 | 0.0087 | 0.0178 |
Brugia malayi | Pre-SET motif family protein | 0.0217 | 0.1053 | 0.2604 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0051 | 0.0088 | 1 |
Plasmodium vivax | serine-repeat antigen (SERA), putative | 0.006 | 0.0139 | 0.0962 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0326 | 0.1688 | 0.8952 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0326 | 0.1688 | 0.4044 |
Loa Loa (eye worm) | cysteine protease | 0.0185 | 0.0868 | 0.2143 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0284 | 0.1444 | 0.3583 |
Plasmodium vivax | serine-repeat antigen 4 (SERA) | 0.006 | 0.0139 | 0.0962 |
Echinococcus multilocularis | geminin | 0.0189 | 0.0894 | 0.0814 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0185 | 0.0868 | 0.4308 |
Schistosoma mansoni | hypothetical protein | 0.005 | 0.0082 | 0.0165 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0051 | 0.0087 | 0.019 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0012 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0139 | 0.0319 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0185 | 0.0868 | 0.4308 |
Brugia malayi | cathepsin L-like precursor | 0.013 | 0.0545 | 0.1335 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.013 | 0.0545 | 0.24 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0326 | 0.1688 | 0.8952 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0139 | 0.0319 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0139 | 0.0319 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.006 | 0.0139 | 0.0298 |
Echinococcus granulosus | cathepsin b | 0.0724 | 0.401 | 0.9334 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0724 | 0.401 | 0.9346 |
Entamoeba histolytica | hypothetical protein | 0.006 | 0.0139 | 0.0655 |
Echinococcus multilocularis | cathepsin b | 0.0724 | 0.401 | 0.3957 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0115 | 0.0462 | 0.4794 |
Entamoeba histolytica | cysteine protease, putative | 0.0115 | 0.0462 | 0.4794 |
Plasmodium vivax | serine-repeat antigen 4 (SERA), putative | 0.006 | 0.0139 | 0.0962 |
Onchocerca volvulus | 0.0185 | 0.0868 | 0.6866 | |
Loa Loa (eye worm) | ctsf protein | 0.0185 | 0.0868 | 0.2143 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.035 | 0.1832 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0185 | 0.0868 | 0.4308 |
Plasmodium vivax | vivapain-3 | 0.0115 | 0.0462 | 0.3419 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0185 | 0.0868 | 0.4308 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0185 | 0.0868 | 0.4308 |
Entamoeba histolytica | cysteine protease, putative | 0.006 | 0.0139 | 0.0655 |
Echinococcus multilocularis | cathepsin b | 0.0724 | 0.401 | 0.3957 |
Mycobacterium ulcerans | hypothetical protein | 0.0051 | 0.0088 | 1 |
Plasmodium falciparum | dipeptidyl aminopeptidase 3 | 0.0137 | 0.059 | 0.4392 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.006 | 0.0139 | 0.0298 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0115 | 0.0462 | 0.0897 |
Plasmodium falciparum | serine repeat antigen 8 | 0.006 | 0.0139 | 0.0962 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0185 | 0.0868 | 0.1858 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0185 | 0.0868 | 0.4308 |
Schistosoma mansoni | subfamily C1A non-peptidase homologue (C01 family) | 0.006 | 0.0139 | 0.0298 |
Giardia lamblia | Cathepsin B precursor | 0.035 | 0.1832 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0326 | 0.1688 | 0.8952 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0056 | 0.0114 | 0.0257 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.006 | 0.0139 | 0.0319 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0185 | 0.0868 | 0.4308 |
Entamoeba histolytica | cysteine protease, putative | 0.0115 | 0.0462 | 0.4794 |
Schistosoma mansoni | cathepsin B (C01 family) | 0.006 | 0.0139 | 0.0298 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0185 | 0.0868 | 0.0788 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.013 | 0.0545 | 0.24 |
Plasmodium falciparum | serine repeat antigen 4 | 0.006 | 0.0139 | 0.0962 |
Schistosoma mansoni | hypothetical protein | 0.0189 | 0.0894 | 0.2064 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0326 | 0.1688 | 0.4044 |
Brugia malayi | Cathepsin L-like precursor | 0.013 | 0.0545 | 0.1335 |
Toxoplasma gondii | cathepsin CPL | 0.0185 | 0.0868 | 0.2241 |
Giardia lamblia | Cathepsin B precursor | 0.035 | 0.1832 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0115 | 0.0462 | 0.4794 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0115 | 0.0462 | 0.1908 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0771 | 0.4289 | 1 |
Echinococcus multilocularis | cathepsin L | 0.0115 | 0.0462 | 0.0378 |
Leishmania major | cathepsin L-like protease | 0.0185 | 0.0868 | 0.4475 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.006 | 0.0139 | 0.0319 |
Echinococcus multilocularis | nuclear receptor co repressor related (ncor) | 0.0308 | 0.1586 | 0.1512 |
Plasmodium vivax | vivapain-2 | 0.0185 | 0.0868 | 0.6508 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0201 | 0.0959 | 0.2173 |
Onchocerca volvulus | 0.0051 | 0.0088 | 0.005 | |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0185 | 0.0868 | 0.6508 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0185 | 0.0868 | 0.4308 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0056 | 0.0114 | 0.0257 |
Leishmania major | cathepsin L-like protease | 0.0326 | 0.1688 | 0.9177 |
Trypanosoma cruzi | cysteine protease, putative | 0.0115 | 0.0462 | 0.0897 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0012 | 0.0002 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0185 | 0.0868 | 0.4308 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0185 | 0.0868 | 0.4308 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0051 | 0.0088 | 1 |
Entamoeba histolytica | papain family cysteine protease domain containing protein | 0.006 | 0.0139 | 0.0655 |
Onchocerca volvulus | 0.013 | 0.0545 | 0.4045 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0185 | 0.0868 | 0.4308 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0012 | 0.0002 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0326 | 0.1688 | 0.8952 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0185 | 0.0868 | 0.194 |
Brugia malayi | Cathepsin L-like precursor | 0.0185 | 0.0868 | 0.2143 |
Brugia malayi | Cathepsin L-like precursor | 0.013 | 0.0545 | 0.1335 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0012 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0088 | 0.0191 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0185 | 0.0868 | 0.4308 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0326 | 0.1688 | 0.4044 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.005 | 0.0082 | 0.0177 |
Entamoeba histolytica | cysteine proteinase 2 | 0.0115 | 0.0462 | 0.4794 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0724 | 0.401 | 0.9346 |
Brugia malayi | Cathepsin L-like precursor | 0.0185 | 0.0868 | 0.2143 |
Entamoeba histolytica | cysteine protease, putative | 0.0115 | 0.0462 | 0.4794 |
Plasmodium falciparum | dipeptidyl aminopeptidase 2 | 0.0264 | 0.1328 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0055 | 0.0112 | 0.0252 |
Brugia malayi | cathepsin L precursor | 0.006 | 0.0139 | 0.0319 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0089 | 0.0195 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0055 | 0.0112 | 0.0252 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0326 | 0.1688 | 0.8952 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0051 | 0.0088 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0545 | 0.1335 |
Plasmodium vivax | unspecified product | 0.0115 | 0.0462 | 0.3419 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0185 | 0.0868 | 1 |
Plasmodium falciparum | serine repeat antigen 3 | 0.006 | 0.0139 | 0.0962 |
Loa Loa (eye worm) | hypothetical protein | 0.0284 | 0.1444 | 0.3583 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0051 | 0.0088 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0185 | 0.0868 | 0.4308 |
Entamoeba histolytica | papain family cysteine protease domain containing protein | 0.006 | 0.0139 | 0.0655 |
Entamoeba histolytica | cysteine protease, putative | 0.0115 | 0.0462 | 0.4794 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0185 | 0.0868 | 0.0788 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0051 | 0.0089 | 0.0182 |
Plasmodium vivax | vivapain-2 | 0.0185 | 0.0868 | 0.6508 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0185 | 0.0868 | 0.4308 |
Entamoeba histolytica | cysteine protease, putative | 0.006 | 0.0139 | 0.0655 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0185 | 0.0868 | 0.4308 |
Entamoeba histolytica | cysteine protease, putative | 0.006 | 0.0139 | 0.0655 |
Entamoeba histolytica | cysteine protease, putative | 0.006 | 0.0139 | 0.0655 |
Plasmodium vivax | unspecified product | 0.0055 | 0.0112 | 0.076 |
Loa Loa (eye worm) | cathepsin B | 0.035 | 0.1832 | 0.4554 |
Plasmodium vivax | serine-repeat antigen 2 (SERA) | 0.006 | 0.0139 | 0.0962 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.013 | 0.0545 | 0.1335 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.035 | 0.1832 | 0.4413 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0051 | 0.0088 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0185 | 0.0868 | 0.4308 |
Onchocerca volvulus | Cathepsin L homolog | 0.0185 | 0.0868 | 0.6866 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0051 | 0.0087 | 0.0178 |
Entamoeba histolytica | cysteine protease, putative | 0.0185 | 0.0868 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0185 | 0.0868 | 0.6508 |
Loa Loa (eye worm) | fibroinase | 0.0185 | 0.0868 | 0.2143 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.0055 | 0.0112 | 0.0252 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0545 | 0.1335 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0326 | 0.1688 | 0.8952 |
Schistosoma mansoni | cathepsin s | 0.0055 | 0.0112 | 0.0236 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0112 | 0.0252 |
Plasmodium vivax | serine-repeat antigen (SERA) | 0.006 | 0.0139 | 0.0962 |
Schistosoma mansoni | dipeptidyl-peptidase I (C01 family) | 0.0264 | 0.1328 | 0.3077 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0038 | 0.0012 | 0.5 |
Echinococcus granulosus | cathepsin l1 | 0.013 | 0.0545 | 0.1089 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0264 | 0.1328 | 0.7021 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0055 | 0.0112 | 0.0252 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0137 | 0.059 | 0.2664 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0246 | 0.1225 | 0.2706 |
Leishmania major | cathepsin L-like protease | 0.0326 | 0.1688 | 0.9177 |
Brugia malayi | fibroinase precursor | 0.006 | 0.0139 | 0.0319 |
Plasmodium vivax | serine-repeat antigen 3 (SERA) | 0.006 | 0.0139 | 0.0962 |
Giardia lamblia | Encystation-specific protease | 0.0137 | 0.059 | 0.2664 |
Brugia malayi | Cathepsin L-like precursor | 0.0185 | 0.0868 | 0.2143 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0185 | 0.0868 | 0.0788 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0545 | 0.1335 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0139 | 0.0319 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0115 | 0.0462 | 0.0897 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0326 | 0.1688 | 0.8952 |
Toxoplasma gondii | cathepsin CPC1 | 0.0264 | 0.1328 | 0.5939 |
Plasmodium vivax | vivapain-1 | 0.0115 | 0.0462 | 0.3419 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.035 | 0.1832 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0185 | 0.0868 | 0.4308 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0186 | 0.0876 | 0.4357 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0115 | 0.0462 | 0.1053 |
Plasmodium vivax | serine-repeat antigen 5 (SERA) | 0.006 | 0.0139 | 0.0962 |
Brugia malayi | Papain family cysteine protease containing protein | 0.006 | 0.0139 | 0.0319 |
Entamoeba histolytica | cysteine protease, putative | 0.0115 | 0.0462 | 0.4794 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0115 | 0.0462 | 0.0897 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.027 | 0.1365 | 0.3215 |
Leishmania major | cathepsin L-like protease | 0.0185 | 0.0868 | 0.4475 |
Echinococcus granulosus | cathepsin l1 | 0.0185 | 0.0868 | 0.1858 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0137 | 0.059 | 0.2664 |
Entamoeba histolytica | cysteine proteinase, putative | 0.013 | 0.0545 | 0.5861 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.006 | 0.0139 | 0.0319 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0724 | 0.401 | 0.9346 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0724 | 0.401 | 1 |
Plasmodium falciparum | serine repeat antigen 5 | 0.006 | 0.0139 | 0.0962 |
Entamoeba histolytica | cysteine protease, putative | 0.006 | 0.0139 | 0.0655 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0185 | 0.0868 | 0.1858 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0114 | 0.0257 |
Leishmania major | cathepsin L-like protease | 0.0185 | 0.0868 | 0.4475 |
Brugia malayi | Cathepsin L-like precursor | 0.0185 | 0.0868 | 0.2143 |
Entamoeba histolytica | cysteine protease, putative | 0.0115 | 0.0462 | 0.4794 |
Schistosoma mansoni | cathepsin C | 0.006 | 0.0139 | 0.0298 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0088 | 0.0191 |
Onchocerca volvulus | 0.0185 | 0.0868 | 0.6866 | |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.006 | 0.0139 | 0.0298 |
Loa Loa (eye worm) | cysteine proteinase cathepsin Z | 0.006 | 0.0139 | 0.0319 |
Plasmodium vivax | serine-repeat antigen (SERA), putative | 0.006 | 0.0139 | 0.0962 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0012 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0246 | 0.1225 | 0.3035 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0115 | 0.0462 | 0.1053 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.013 | 0.0545 | 0.1248 |
Echinococcus granulosus | cathepsin L | 0.006 | 0.0139 | 0.0122 |
Echinococcus multilocularis | cysteine protease | 0.0185 | 0.0868 | 0.0788 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0112 | 0.0252 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0185 | 0.0868 | 0.6508 |
Echinococcus granulosus | cathepsin L | 0.0115 | 0.0462 | 0.0891 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0056 | 0.0114 | 0.0257 |
Giardia lamblia | Cathepsin B precursor | 0.035 | 0.1832 | 1 |
Plasmodium vivax | dipeptidyl aminopeptidase 3, putative | 0.0137 | 0.059 | 0.4392 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.006 | 0.0139 | 0.0298 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0185 | 0.0868 | 0.4308 |
Brugia malayi | Cathepsin L-like precursor | 0.0185 | 0.0868 | 0.2143 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0246 | 0.1225 | 0.1147 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0115 | 0.0462 | 0.4794 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0139 | 0.0319 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0115 | 0.0462 | 0.4794 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0115 | 0.0462 | 0.3419 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0051 | 0.0088 | 1 |
Echinococcus multilocularis | cathepsin L | 0.006 | 0.0139 | 0.0052 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.006 | 0.0139 | 0.0319 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.006 | 0.0139 | 0.0319 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0115 | 0.0462 | 0.1127 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0185 | 0.0868 | 0.2003 |
Onchocerca volvulus | Cathepsin L homolog | 0.0185 | 0.0868 | 0.6866 |
Brugia malayi | hypothetical protein | 0.0246 | 0.1225 | 0.3035 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0115 | 0.0462 | 0.1053 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0038 | 0.0012 | 0.139 |
Brugia malayi | cathepsin L-like cysteine proteinase | 0.006 | 0.0139 | 0.0319 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0112 | 0.0252 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0051 | 0.0087 | 0.019 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0326 | 0.1688 | 0.8952 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0185 | 0.0868 | 0.4308 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.006 | 0.0139 | 0.0068 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0051 | 0.0088 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.006 | 0.0139 | 0.0298 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0185 | 0.0868 | 0.4308 |
Toxoplasma gondii | cathepsin B | 0.035 | 0.1832 | 1 |
Echinococcus multilocularis | tumor protein p63 | 0.0352 | 0.184 | 0.1768 |
Entamoeba histolytica | cysteine protease, putative | 0.0115 | 0.0462 | 0.4794 |
Brugia malayi | Papain family cysteine protease containing protein | 0.006 | 0.0139 | 0.0319 |
Onchocerca volvulus | 0.0051 | 0.0089 | 0.0065 | |
Plasmodium vivax | serine-repeat antigen (SERA) | 0.006 | 0.0139 | 0.0962 |
Entamoeba histolytica | cysteine protease, putative | 0.0115 | 0.0462 | 0.4794 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0185 | 0.0868 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0185 | 0.0868 | 0.4308 |
Onchocerca volvulus | 0.0185 | 0.0868 | 0.6866 | |
Echinococcus multilocularis | cysteine protease | 0.0185 | 0.0868 | 0.0788 |
Onchocerca volvulus | 0.0247 | 0.1227 | 1 | |
Trichomonas vaginalis | set domain proteins, putative | 0.0247 | 0.1227 | 0.6428 |
Plasmodium vivax | dipeptidyl aminopeptidase 2, putative | 0.0264 | 0.1328 | 1 |
Brugia malayi | cahepsin L-like non-peptiedase homolog | 0.006 | 0.0139 | 0.0319 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.035 | 0.1832 | 0.4256 |
Entamoeba histolytica | cysteine protease, putative | 0.0115 | 0.0462 | 0.4794 |
Onchocerca volvulus | 0.0185 | 0.0868 | 0.6866 | |
Plasmodium falciparum | serine repeat antigen 6 | 0.006 | 0.0139 | 0.0962 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0051 | 0.0088 | 1 |
Leishmania major | cathepsin L-like protease | 0.0185 | 0.0868 | 0.4475 |
Brugia malayi | AMP-binding enzyme family protein | 0.0051 | 0.0088 | 0.0191 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.035 | 0.1832 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0115 | 0.0462 | 0.4794 |
Plasmodium falciparum | dipeptidyl aminopeptidase 1 | 0.0264 | 0.1328 | 1 |
Schistosoma mansoni | cathepsin S (C01 family) | 0.006 | 0.0139 | 0.0298 |
Brugia malayi | Papain family cysteine protease containing protein | 0.006 | 0.0139 | 0.0319 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0185 | 0.0868 | 0.2143 |
Onchocerca volvulus | 0.006 | 0.0139 | 0.0497 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0326 | 0.1688 | 0.8952 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0115 | 0.0462 | 0.0897 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0185 | 0.0868 | 0.2143 |
Plasmodium falciparum | serine repeat antigen 1 | 0.006 | 0.0139 | 0.0962 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0088 | 0.0191 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0115 | 0.0462 | 0.0891 |
Plasmodium falciparum | serine repeat antigen 7 | 0.006 | 0.0139 | 0.0962 |
Entamoeba histolytica | cysteine protease, putative | 0.0115 | 0.0462 | 0.4794 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0115 | 0.0462 | 0.4794 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.006 | 0.0139 | 0.0298 |
Entamoeba histolytica | cysteine protease, putative | 0.0115 | 0.0462 | 0.4794 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0051 | 0.0088 | 1 |
Onchocerca volvulus | 0.0185 | 0.0868 | 0.6866 | |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0051 | 0.0088 | 0.5 |
Plasmodium vivax | dipeptidyl aminopeptidase 1, putative | 0.0264 | 0.1328 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0185 | 0.0868 | 0.2143 |
Onchocerca volvulus | 0.0185 | 0.0868 | 0.6866 | |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0326 | 0.1688 | 0.4044 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0051 | 0.0087 | 0.0178 |
Brugia malayi | AMP-binding enzyme family protein | 0.0051 | 0.0088 | 0.0191 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0139 | 0.0319 |
Leishmania major | cysteine peptidase A (CPA) | 0.0185 | 0.0868 | 0.4475 |
Echinococcus granulosus | cysteine protease | 0.0115 | 0.0462 | 0.0891 |
Onchocerca volvulus | 0.0185 | 0.0868 | 0.6866 | |
Echinococcus granulosus | microtubule associated protein 2 | 0.0771 | 0.4289 | 1 |
Echinococcus granulosus | nuclear receptor co repressor related ncor | 0.0308 | 0.1586 | 0.3566 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.006 | 0.0139 | 0.0298 |
Brugia malayi | Cathepsin L-like precursor | 0.0185 | 0.0868 | 0.2143 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0185 | 0.0868 | 0.4308 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0326 | 0.1688 | 0.8952 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0217 | 0.1053 | 0.2604 |
Echinococcus granulosus | geminin | 0.0189 | 0.0894 | 0.192 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0115 | 0.0462 | 0.1908 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0115 | 0.0462 | 0.1127 |
Entamoeba histolytica | cysteine protease, putative | 0.006 | 0.0139 | 0.0655 |
Loa Loa (eye worm) | hypothetical protein | 0.0185 | 0.0868 | 0.2143 |
Plasmodium falciparum | serine repeat antigen 2 | 0.006 | 0.0139 | 0.0962 |
Onchocerca volvulus | Cathepsin F homolog | 0.0185 | 0.0868 | 0.6866 |
Plasmodium falciparum | serine repeat antigen 9 | 0.006 | 0.0139 | 0.0962 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0185 | 0.0868 | 0.4308 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0185 | 0.0868 | 0.2003 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
RFU (binding) | = 1.28 | Inhibition of human MDR1 expressed in mouse L5178Y cells assessed as reduction of rhodamine-123 uptake by measuring fluorescence activity ratio at 1 uM preincubated for 10 mins measured after 40 mins relative to control | ChEMBL. | 23199479 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.