Detailed information for compound 1730578

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 1458.83 | Formula: C78H115N13O14
  • H donors: 14 H acceptors: 14 LogP: 8.26 Rotable bonds: 39
    Rule of 5 violations (Lipinski): 4
  • SMILES: O=C(N[C@H]1CCC[C@@H]1C(=O)N[C@H]1CCC[C@@H]1C(=O)N[C@H]1CCC[C@@H]1C(=O)N[C@H]1CCC[C@@H]1C(=O)N[C@H]1CCC[C@@H]1C(=O)N[C@H]1CCC[C@@H]1C(=O)N[C@H]1CCC[C@@H]1C(=O)N[C@H]1CCC[C@@H]1C(=O)N[C@H]1CCC[C@@H]1C(=O)N)C[C@@H](NC(=O)[C@H]1CCC[C@@H]1NC(=O)[C@H]1CCC[C@@H]1NC(=O)C)Cc1ccc(cc1)O
  • InChi: 1S/C78H115N13O14/c1-41(92)80-57-25-3-14-46(57)70(97)84-59-27-5-16-48(59)69(96)81-43(39-42-35-37-44(93)38-36-42)40-67(94)82-58-26-4-15-47(58)71(98)85-61-29-7-18-50(61)73(100)87-63-31-9-20-52(63)75(102)89-65-33-11-22-54(65)77(104)91-66-34-12-23-55(66)78(105)90-64-32-10-21-53(64)76(103)88-62-30-8-19-51(62)74(101)86-60-28-6-17-49(60)72(99)83-56-24-2-13-45(56)68(79)95/h35-38,43,45-66,93H,2-34,39-40H2,1H3,(H2,79,95)(H,80,92)(H,81,96)(H,82,94)(H,83,99)(H,84,97)(H,85,98)(H,86,101)(H,87,100)(H,88,103)(H,89,102)(H,90,105)(H,91,104)/t43-,45-,46-,47-,48-,49-,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,63-,64-,65-,66-/m0/s1
  • InChiKey: BLDZEFJRJOVGDI-SDJVVBLVSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.0084 0.0325 0.0679
Mycobacterium ulcerans monoamine oxidase 0.011 0.0496 0.0496
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0766 0.4791 0.9625
Loa Loa (eye worm) hypothetical protein 0.0084 0.0325 0.0653
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0766 0.4791 0.8129
Schistosoma mansoni transient receptor potential channel 0.0766 0.4791 0.9625
Brugia malayi Transient-receptor-potential like protein 0.0766 0.4791 0.9625
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0766 0.4791 0.9625
Echinococcus granulosus sodium leak channel non selective protein 0.0766 0.4791 0.9625
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0766 0.4791 0.9625
Echinococcus granulosus potassium voltage gated channel protein 0.0766 0.4791 0.9625
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0254 0.051
Mycobacterium tuberculosis Possible oxidoreductase 0.011 0.0496 0.0535
Loa Loa (eye worm) hypothetical protein 0.0057 0.0152 0.0306
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.011 0.0496 1
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0766 0.4791 0.8129
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.1452 0.928 1
Plasmodium vivax protoporphyrinogen oxidase, putative 0.011 0.0496 1
Echinococcus multilocularis potassium voltage gated channel protein 0.0766 0.4791 0.8129
Echinococcus multilocularis transient receptor potential cation channel 0.0766 0.4791 0.8129
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0084 0.0325 0.0653
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.011 0.0496 1
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0766 0.4791 0.9625
Loa Loa (eye worm) hypothetical protein 0.0084 0.0325 0.0653
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0766 0.4791 0.9625
Brugia malayi Carboxylesterase family protein 0.0084 0.0325 0.0653
Brugia malayi cation channel family protein 0.0766 0.4791 0.9625
Echinococcus granulosus voltage dependent calcium channel 0.0766 0.4791 0.9625
Schistosoma mansoni voltage-gated potassium channel 0.0766 0.4791 0.9625
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0766 0.4791 0.9625
Schistosoma mansoni vesicular amine transporter 0.0766 0.4791 0.9625
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0766 0.4791 0.8129
Schistosoma mansoni voltage-gated potassium channel 0.0766 0.4791 0.9625
Leishmania major UDP-galactopyranose mutase 0.011 0.0496 0.1035
Schistosoma mansoni acetylcholinesterase 0.0084 0.0325 0.0653
Echinococcus multilocularis carboxylesterase 5A 0.0496 0.3026 0.5134
Chlamydia trachomatis protoporphyrinogen oxidase 0.011 0.0496 0.5
Loa Loa (eye worm) carboxylesterase 0.0084 0.0325 0.0653
Loa Loa (eye worm) hypothetical protein 0.0766 0.4791 0.9625
Loa Loa (eye worm) hypothetical protein 0.0766 0.4791 0.9625
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0766 0.4791 0.8129
Schistosoma mansoni voltage-gated potassium channel 0.0766 0.4791 0.9625
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0084 0.0325 0.0653
Echinococcus granulosus TRP transient receptor potential channel 0.0766 0.4791 0.9625
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.011 0.0496 0.5
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0084 0.0325 0.0679
Echinococcus granulosus calcium activated potassium channel 0.0766 0.4791 0.9625
Echinococcus multilocularis sodium leak channel non selective protein 0.0766 0.4791 0.8129
Echinococcus multilocularis potassium voltage gated channel protein 0.0766 0.4791 0.8129
Brugia malayi Cyclic-nucleotide gated cation channel 0.0766 0.4791 0.9625
Brugia malayi Carboxylesterase family protein 0.0084 0.0325 0.0653
Loa Loa (eye worm) hypothetical protein 0.0766 0.4791 0.9625
Plasmodium vivax hypothetical protein, conserved 0.011 0.0496 1
Loa Loa (eye worm) voltage-gated calcium channel 0.0766 0.4791 0.9625
Loa Loa (eye worm) hypothetical protein 0.0766 0.4791 0.9625
Loa Loa (eye worm) voltage-dependent calcium channel 0.0766 0.4791 0.9625
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0084 0.0325 0.0653
Schistosoma mansoni voltage-gated potassium channel 0.0766 0.4791 0.9625
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0766 0.4791 0.8129
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0766 0.4791 0.9625
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0766 0.4791 0.9625
Echinococcus multilocularis acetylcholinesterase 0.0496 0.3026 0.5134
Mycobacterium ulcerans protoporphyrinogen oxidase 0.011 0.0496 0.0496
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0766 0.4791 0.9625
Loa Loa (eye worm) ryanodine receptor 0.0766 0.4791 0.9625
Schistosoma mansoni transient receptor potential channel 4 0.0766 0.4791 0.9625
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0057 0.0152 0.0306
Loa Loa (eye worm) hypothetical protein 0.0795 0.4977 1
Echinococcus multilocularis voltage gated potassium channel 0.0766 0.4791 0.8129
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0766 0.4791 0.8129
Echinococcus granulosus potassium voltage gated channel protein 0.0766 0.4791 0.9625
Echinococcus multilocularis conserved hypothetical protein 0.0766 0.4791 0.8129
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0084 0.0325 0.035
Schistosoma mansoni voltage-gated potassium channel 0.0766 0.4791 0.9625
Schistosoma mansoni voltage-gated potassium channel 0.0766 0.4791 0.9625
Schistosoma mansoni ryanodine receptor related 0.0766 0.4791 0.9625
Loa Loa (eye worm) hypothetical protein 0.0496 0.3026 0.6079
Loa Loa (eye worm) hypothetical protein 0.0766 0.4791 0.9625
Echinococcus granulosus transient receptor potential cation channel 0.0795 0.4977 1
Schistosoma mansoni voltage-gated potassium channel 0.0766 0.4791 0.9625
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0766 0.4791 0.8129
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0766 0.4791 0.9625
Schistosoma mansoni voltage-gated potassium channel 0.0766 0.4791 0.9625
Loa Loa (eye worm) TAR-binding protein 0.0073 0.0254 0.051
Echinococcus granulosus shaker cognate 0.0766 0.4791 0.9625
Echinococcus multilocularis calcium activated potassium channel 0.0766 0.4791 0.8129
Loa Loa (eye worm) hypothetical protein 0.0084 0.0325 0.0653
Echinococcus multilocularis potassium voltage gated channel protein 0.0766 0.4791 0.8129
Schistosoma mansoni transient receptor potential channel 0.0766 0.4791 0.9625
Loa Loa (eye worm) hypothetical protein 0.0766 0.4791 0.9625
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0766 0.4791 0.9625
Echinococcus granulosus transient receptor potential cation channel 0.0766 0.4791 0.9625
Brugia malayi cation channel family protein 0.0766 0.4791 0.9625
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0766 0.4791 0.8129
Loa Loa (eye worm) hypothetical protein 0.0496 0.3026 0.6079
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0766 0.4791 1
Brugia malayi hypothetical protein 0.0766 0.4791 0.9625
Loa Loa (eye worm) hypothetical protein 0.011 0.0496 0.0997
Echinococcus multilocularis neuroligin 0.0084 0.0325 0.0552
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0766 0.4791 0.9625
Echinococcus granulosus hypothetical protein 0.0766 0.4791 0.9625
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0766 0.4791 0.9625
Brugia malayi RNA recognition motif domain containing protein 0.0073 0.0254 0.051
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0254 0.051
Loa Loa (eye worm) hypothetical protein 0.0766 0.4791 0.9625
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0766 0.4791 0.9625
Brugia malayi Carboxylesterase family protein 0.0084 0.0325 0.0653
Echinococcus multilocularis transient receptor potential cation channel 0.0766 0.4791 0.8129
Brugia malayi amine oxidase, flavin-containing family protein 0.011 0.0496 0.0997
Echinococcus multilocularis ryanodine receptor 44f 0.0766 0.4791 0.8129
Loa Loa (eye worm) hypothetical protein 0.0766 0.4791 0.9625
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0766 0.4791 0.8129
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0766 0.4791 0.9625
Brugia malayi hypothetical protein 0.011 0.0496 0.0997
Onchocerca volvulus 0.0766 0.4791 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0057 0.0152 0.0306
Loa Loa (eye worm) hypothetical protein 0.0766 0.4791 0.9625
Loa Loa (eye worm) calcium channel 0.0766 0.4791 0.9625
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0766 0.4791 0.9625
Echinococcus granulosus neuroligin 0.0084 0.0325 0.0653
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0766 0.4791 0.9625
Echinococcus multilocularis acetylcholinesterase 0.0496 0.3026 0.5134
Echinococcus multilocularis transient receptor potential cation channel 0.0766 0.4791 0.8129
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.011 0.0496 0.1035
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0766 0.4791 0.9625
Echinococcus multilocularis shaker cognate 0.0766 0.4791 0.8129
Echinococcus multilocularis short transient receptor potential channel 6 0.0795 0.4977 0.8446
Echinococcus multilocularis 0.011 0.0496 0.0842
Echinococcus granulosus transient receptor potential cation channel 0.0766 0.4791 0.9625
Schistosoma mansoni BC026374 protein (S09 family) 0.0084 0.0325 0.0653
Loa Loa (eye worm) hypothetical protein 0.0766 0.4791 0.9625
Loa Loa (eye worm) hypothetical protein 0.011 0.0496 0.0997
Echinococcus multilocularis voltage dependent calcium channel 0.0766 0.4791 0.8129
Loa Loa (eye worm) voltage-gated potassium channel 0.0766 0.4791 0.9625
Onchocerca volvulus 0.011 0.0496 0.1035
Loa Loa (eye worm) hypothetical protein 0.0766 0.4791 0.9625
Mycobacterium tuberculosis Conserved hypothetical protein 0.011 0.0496 0.0535
Brugia malayi Carboxylesterase family protein 0.0084 0.0325 0.0653
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0254 0.051
Echinococcus granulosus hyperpolarization activated cyclic 0.0766 0.4791 0.9625
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0254 0.051
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0766 0.4791 0.8129
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0766 0.4791 0.9625
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.011 0.0496 0.5
Schistosoma mansoni voltage-gated potassium channel 0.0766 0.4791 0.9625
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0766 0.4791 0.9625
Toxoplasma gondii transporter, cation channel family protein 0.0766 0.4791 1
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0766 0.4791 0.9625
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0766 0.4791 0.8129
Loa Loa (eye worm) hypothetical protein 0.011 0.0496 0.0997
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0766 0.4791 0.9625
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0766 0.4791 0.8129
Echinococcus multilocularis potassium voltage gated channel protein 0.0766 0.4791 0.8129
Loa Loa (eye worm) hypothetical protein 0.0766 0.4791 0.9625
Schistosoma mansoni transient receptor potential channel 0.0795 0.4977 1
Loa Loa (eye worm) ion channel NompC 0.0766 0.4791 0.9625
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0766 0.4791 0.9625
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0766 0.4791 1
Loa Loa (eye worm) hypothetical protein 0.0766 0.4791 0.9625
Schistosoma mansoni amine oxidase 0.011 0.0496 0.0997
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0766 0.4791 0.9625
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0766 0.4791 1
Brugia malayi ion channel NompC 0.0766 0.4791 0.9625
Onchocerca volvulus 0.0084 0.0325 0.0679
Brugia malayi latrophilin 2 splice variant baaae 0.0039 0.0033 0.0067
Echinococcus multilocularis transient receptor potential cation channel 0.0766 0.4791 0.8129
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0766 0.4791 0.9625
Echinococcus multilocularis transient receptor potential cation channel 0.0795 0.4977 0.8446
Echinococcus granulosus lysine specific histone demethylase 1A 0.011 0.0496 0.0997
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0766 0.4791 0.8129
Echinococcus granulosus sodium channel protein 0.0766 0.4791 0.9625
Brugia malayi hypothetical protein 0.0084 0.0325 0.0653
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0766 0.4791 1
Toxoplasma gondii transporter, cation channel family protein 0.0766 0.4791 1
Echinococcus granulosus transient receptor potential cation channel 0.0766 0.4791 0.9625
Schistosoma mansoni voltage-gated potassium channel 0.0766 0.4791 0.9625
Echinococcus granulosus transient receptor potential cation channel 0.0766 0.4791 0.9625
Echinococcus multilocularis short transient receptor potential channel 6 0.0766 0.4791 0.8129
Leishmania major hypothetical protein, conserved 0.0766 0.4791 1
Mycobacterium ulcerans oxidoreductase 0.011 0.0496 0.0496
Loa Loa (eye worm) RNA binding protein 0.0073 0.0254 0.051
Brugia malayi SWIRM domain containing protein 0.011 0.0496 0.0997
Echinococcus granulosus acetylcholinesterase 0.0496 0.3026 0.6079
Brugia malayi TAR-binding protein 0.0073 0.0254 0.051
Echinococcus multilocularis two pore calcium channel protein 1 0.0766 0.4791 0.8129
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0766 0.4791 0.9625
Schistosoma mansoni voltage-gated potassium channel 0.0766 0.4791 0.9625
Echinococcus granulosus carboxylesterase 5A 0.0496 0.3026 0.6079
Schistosoma mansoni voltage-gated potassium channel 0.0766 0.4791 0.9625
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0766 0.4791 0.9625
Echinococcus granulosus BC026374 protein S09 family 0.0084 0.0325 0.0653
Loa Loa (eye worm) hypothetical protein 0.0039 0.0033 0.0067
Echinococcus granulosus voltage gated hydrogen channel 1 0.0766 0.4791 0.9625
Echinococcus granulosus ryanodine receptor 44f 0.0766 0.4791 0.9625
Brugia malayi Carboxylesterase family protein 0.0496 0.3026 0.6079
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0766 0.4791 0.9625
Loa Loa (eye worm) hypothetical protein 0.0084 0.0325 0.0653
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0766 0.4791 0.9625
Echinococcus granulosus lysine specific histone demethylase 1A 0.011 0.0496 0.0997
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0084 0.0325 0.0653
Loa Loa (eye worm) hypothetical protein 0.0084 0.0325 0.0653
Loa Loa (eye worm) hypothetical protein 0.0766 0.4791 0.9625
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0766 0.4791 1
Schistosoma mansoni voltage-gated potassium channel 0.0766 0.4791 0.9625
Loa Loa (eye worm) hypothetical protein 0.0766 0.4791 0.9625
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0766 0.4791 0.9625
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0766 0.4791 0.9625
Plasmodium vivax hypothetical protein, conserved 0.011 0.0496 1
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0766 0.4791 0.9625
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0766 0.4791 1
Leishmania major hypothetical protein, unknown function 0.0766 0.4791 1
Echinococcus multilocularis tar DNA binding protein 0.0073 0.0254 0.0431
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0219 0.1207 0.13
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0766 0.4791 0.9625
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0766 0.4791 1
Loa Loa (eye worm) hypothetical protein 0.011 0.0496 0.0997
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0766 0.4791 0.9625
Echinococcus granulosus para nitrobenzyl esterase 0.0084 0.0325 0.0653
Schistosoma mansoni voltage-gated potassium channel 0.0766 0.4791 0.9625
Echinococcus granulosus potassium voltage gated channel protein 0.0766 0.4791 0.9625
Echinococcus multilocularis transient receptor potential cation channel 0.0795 0.4977 0.8446
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0766 0.4791 0.9625
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0766 0.4791 0.9625
Echinococcus granulosus hyperpolarization activated cyclic 0.0766 0.4791 0.9625
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0766 0.4791 0.8129
Toxoplasma gondii hypothetical protein 0.0766 0.4791 1
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0766 0.4791 0.9625
Echinococcus multilocularis protoporphyrinogen oxidase 0.011 0.0496 0.0842
Mycobacterium ulcerans carboxylesterase, LipT 0.0084 0.0325 0.0325
Loa Loa (eye worm) hypothetical protein 0.0766 0.4791 0.9625
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0766 0.4791 0.9625
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0766 0.4791 0.9625
Onchocerca volvulus 0.0084 0.0325 0.0679
Echinococcus multilocularis hyperpolarization activated cyclic 0.0766 0.4791 0.8129
Echinococcus multilocularis BC026374 protein (S09 family) 0.0084 0.0325 0.0552
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0766 0.4791 1
Echinococcus multilocularis voltage gated potassium channel 0.0766 0.4791 0.8129
Schistosoma mansoni Lysine-specific histone demethylase 1 0.011 0.0496 0.0997
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0766 0.4791 1
Schistosoma mansoni voltage-gated ion channel 0.0766 0.4791 0.9625
Echinococcus multilocularis sodium channel protein 0.0766 0.4791 0.8129
Echinococcus multilocularis two pore calcium channel protein 2 0.0766 0.4791 0.8129
Schistosoma mansoni gliotactin 0.0084 0.0325 0.0653
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.011 0.0496 0.0997
Loa Loa (eye worm) hypothetical protein 0.0766 0.4791 0.9625
Brugia malayi RNA binding protein 0.0073 0.0254 0.051
Echinococcus granulosus potassium voltage gated channel protein 0.0766 0.4791 0.9625
Echinococcus multilocularis potassium large conductance calcium activated 0.0766 0.4791 0.8129
Echinococcus granulosus two pore calcium channel protein 1 0.0766 0.4791 0.9625
Schistosoma mansoni voltage-dependent calcium channel 0.0766 0.4791 0.9625
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0766 0.4791 0.9625
Schistosoma mansoni calcium-activated potassium channel 0.0766 0.4791 0.9625
Loa Loa (eye worm) hypothetical protein 0.011 0.0496 0.0997
Trypanosoma cruzi UDP-galactopyranose mutase 0.011 0.0496 0.1035
Toxoplasma gondii histone lysine-specific demethylase 0.011 0.0496 0.1035
Onchocerca volvulus 0.0084 0.0325 0.0679
Loa Loa (eye worm) voltage-gated potassium channel 0.0766 0.4791 0.9625
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0766 0.4791 0.9625
Echinococcus multilocularis lysine specific histone demethylase 1A 0.011 0.0496 0.0842
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0766 0.4791 0.9625
Echinococcus granulosus tar DNA binding protein 0.0073 0.0254 0.051
Echinococcus granulosus voltage gated potassium channel 0.0766 0.4791 0.9625
Schistosoma mansoni hypothetical protein 0.0766 0.4791 0.9625
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0766 0.4791 0.9625
Echinococcus multilocularis hyperpolarization activated cyclic 0.0766 0.4791 0.8129
Echinococcus granulosus short transient receptor potential channel 6 0.0766 0.4791 0.9625
Toxoplasma gondii transporter, cation channel family protein 0.0766 0.4791 1
Schistosoma mansoni voltage-gated potassium channel 0.0766 0.4791 0.9625
Schistosoma mansoni voltage-gated cation channel 0.0766 0.4791 0.9625
Brugia malayi voltage-dependent calcium channel 0.0766 0.4791 0.9625
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0084 0.0325 0.035
Loa Loa (eye worm) hypothetical protein 0.0766 0.4791 0.9625
Echinococcus granulosus short transient receptor potential channel 6 0.0795 0.4977 1
Schistosoma mansoni voltage-gated potassium channel 0.0766 0.4791 0.9625
Loa Loa (eye worm) hypothetical protein 0.011 0.0496 0.0997
Onchocerca volvulus 0.0084 0.0325 0.0679
Schistosoma mansoni amine oxidase 0.011 0.0496 0.0997
Echinococcus granulosus acetylcholinesterase 0.0496 0.3026 0.6079
Echinococcus granulosus two pore calcium channel protein 2 0.0766 0.4791 0.9625
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0766 0.4791 0.9625
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0766 0.4791 0.9625
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0766 0.4791 0.8129
Loa Loa (eye worm) acetylcholinesterase 1 0.0496 0.3026 0.6079
Echinococcus multilocularis transient receptor potential gamma protein 0.0766 0.4791 0.8129
Schistosoma mansoni 60S ribosomal protein L21 0.0766 0.4791 0.9625
Mycobacterium tuberculosis Carboxylesterase LipT 0.0084 0.0325 0.035
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0766 0.4791 0.9625
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0084 0.0325 0.0552
Loa Loa (eye worm) hypothetical protein 0.0084 0.0325 0.0653
Echinococcus multilocularis transfer RNA-Gly 0.0766 0.4791 0.8129
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0073 0.0254 0.051
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0766 0.4791 0.9625
Brugia malayi olfactory channel protein osm-9 0.0795 0.4977 1
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0766 0.4791 1
Echinococcus multilocularis voltage dependent calcium channel 0.0766 0.4791 0.8129
Brugia malayi Calcitonin receptor-like protein seb-1 0.0057 0.0152 0.0306
Schistosoma mansoni voltage-gated potassium channel 0.0766 0.4791 0.9625
Loa Loa (eye worm) hypothetical protein 0.0084 0.0325 0.0653
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0766 0.4791 1
Plasmodium falciparum protoporphyrinogen oxidase 0.011 0.0496 0.5
Trypanosoma cruzi UDP-galactopyranose mutase 0.011 0.0496 0.1035
Schistosoma mansoni hypothetical protein 0.0039 0.0033 0.0067
Brugia malayi Carboxylesterase family protein 0.0496 0.3026 0.6079
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0496 0.3026 0.6079
Echinococcus granulosus transient receptor potential cation channel 0.0766 0.4791 0.9625
Loa Loa (eye worm) carboxylesterase 0.0084 0.0325 0.0653
Trichomonas vaginalis spcc417.12 protein, putative 0.0084 0.0325 0.0679
Schistosoma mansoni two-pore calcium channel 0.0766 0.4791 0.9625
Loa Loa (eye worm) hypothetical protein 0.0766 0.4791 0.9625
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0254 0.051
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0766 0.4791 0.8129
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0766 0.4791 0.9625
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0766 0.4791 0.9625
Echinococcus granulosus potassium large conductance calcium activated 0.0766 0.4791 0.9625
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0766 0.4791 0.9625
Echinococcus multilocularis para nitrobenzyl esterase 0.0084 0.0325 0.0552
Echinococcus granulosus voltage gated potassium channel 0.0766 0.4791 0.9625
Toxoplasma gondii hypothetical protein 0.0766 0.4791 1
Echinococcus granulosus transient receptor potential gamma protein 0.0766 0.4791 0.9625
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0766 0.4791 0.9625
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0935 0.5893 1
Loa Loa (eye worm) carboxylesterase 0.0496 0.3026 0.6079
Schistosoma mansoni neuroligin 3 (S09 family) 0.0084 0.0325 0.0653
Loa Loa (eye worm) hypothetical protein 0.0766 0.4791 0.9625
Mycobacterium ulcerans dehydrogenase 0.011 0.0496 0.0496
Echinococcus granulosus voltage dependent calcium channel 0.0766 0.4791 0.9625
Echinococcus granulosus potassium voltage gated channel protein 0.0766 0.4791 0.9625
Loa Loa (eye worm) hypothetical protein 0.0766 0.4791 0.9625
Schistosoma mansoni voltage-gated potassium channel 0.0766 0.4791 0.9625
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0766 0.4791 0.8129
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0766 0.4791 0.9625

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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