Detailed information for compound 1831599

Basic information

Technical information
  • TDR Targets ID: 1831599
  • Name: 3-furan-2-yl-N-[4-(5-methylfuran-2-yl)phenyl] prop-2-enamide
  • MW: 293.317 | Formula: C18H15NO3
  • H donors: 1 H acceptors: 1 LogP: 3.41 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(Nc1ccc(cc1)c1ccc(o1)C)/C=C/c1ccco1
  • InChi: 1S/C18H15NO3/c1-13-4-10-17(22-13)14-5-7-15(8-6-14)19-18(20)11-9-16-3-2-12-21-16/h2-12H,1H3,(H,19,20)/b11-9+
  • InChiKey: VLUHYRKEKGRRKC-PKNBQFBNSA-N  

Network

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Synonyms

  • (E)-3-furan-2-yl-N-[4-(5-methylfuran-2-yl)phenyl]prop-2-enamide
  • 3-(2-furyl)-N-[4-(5-methyl-2-furyl)phenyl]prop-2-enamide
  • (E)-3-(2-furyl)-N-[4-(5-methyl-2-furyl)phenyl]prop-2-enamide
  • 3-(2-furyl)-N-[4-(5-methyl-2-furyl)phenyl]acrylamide
  • (E)-3-(2-furyl)-N-[4-(5-methyl-2-furyl)phenyl]acrylamide
  • (E)-3-Furan-2-yl-N-[4-(5-methyl-furan-2-yl)-phenyl]-acrylamide
  • ASN 03794024
  • ZINC04160865

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus granulosus g protein coupled receptor 0.0095 0.7276 1
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0095 0.7276 1
Echinococcus multilocularis g protein coupled receptor 0.0095 0.7276 1
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0095 0.7276 1
Brugia malayi Dopamine receptor protein 2 0.0095 0.7276 0.7276
Schistosoma mansoni neuropeptide F-like receptor 0.0095 0.7276 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0095 0.7276 1
Schistosoma mansoni amine GPCR 0.0095 0.7276 1
Loa Loa (eye worm) tubulin beta-4 chain 0.0046 0.2712 0.202
Schistosoma mansoni opsin-like receptor 0.0095 0.7276 1
Onchocerca volvulus 0.0095 0.7276 0.5
Loa Loa (eye worm) BEN-1 protein 0.0046 0.2712 0.202
Echinococcus multilocularis neuropeptide receptor 0.0095 0.7276 1
Echinococcus granulosus dro:myosuppressin receptor 0.0095 0.7276 1
Echinococcus granulosus g protein coupled receptor 0.0095 0.7276 1
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Echinococcus multilocularis serotonin receptor 0.0095 0.7276 1
Echinococcus granulosus fmrfamide receptor 0.0095 0.7276 1
Echinococcus granulosus somatostatin receptor 0.0095 0.7276 1
Loa Loa (eye worm) neuropeptide F receptor 0.0095 0.7276 0.7018
Leishmania major beta tubulin 0.0046 0.2712 1
Echinococcus granulosus tm gpcr rhodopsin 0.0095 0.7276 1
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0095 0.7276 1
Brugia malayi hypothetical protein 0.0095 0.7276 0.7276
Brugia malayi AKH receptor 0.0095 0.7276 0.7276
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Brugia malayi GnHR receptor homolog 0.0095 0.7276 0.7276
Brugia malayi follicle stimulating hormone receptor 0.0095 0.7276 0.7276
Schistosoma mansoni alpha-1 adrenergic receptor 0.0095 0.7276 1
Leishmania major beta tubulin 0.0046 0.2712 1
Leishmania major beta tubulin 0.0046 0.2712 1
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0095 0.7276 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0095 0.7276 1
Schistosoma mansoni adenoreceptor 0.0095 0.7276 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0095 0.7276 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0095 0.7276 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0095 0.7276 1
Brugia malayi hypothetical protein 0.0026 0.0866 0.0866
Schistosoma mansoni biogenic amine receptor 0.0095 0.7276 1
Onchocerca volvulus 0.0095 0.7276 0.5
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Brugia malayi neuropeptide F receptor 0.0095 0.7276 0.7276
Loa Loa (eye worm) tubulin beta-2A chain 0.0046 0.2712 0.202
Schistosoma mansoni amine GPCR 0.0095 0.7276 1
Brugia malayi Melatonin receptor type 1A 0.0095 0.7276 0.7276
Echinococcus granulosus rhodopsin orphan GPCR 0.0095 0.7276 1
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Onchocerca volvulus 0.0095 0.7276 0.5
Leishmania major beta tubulin 0.0046 0.2712 1
Schistosoma mansoni hypothetical protein 0.0095 0.7276 1
Trypanosoma brucei beta tubulin 0.0046 0.2712 1
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Echinococcus granulosus rhodopsin orphan GPCR 0.0095 0.7276 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0095 0.7276 1
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0095 0.7276 1
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Leishmania major beta tubulin 0.0046 0.2712 1
Giardia lamblia Beta tubulin 0.0046 0.2712 0.5
Schistosoma mansoni hypothetical protein 0.0095 0.7276 1
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Brugia malayi larval opioid receptor 0.0095 0.7276 0.7276
Echinococcus granulosus g protein coupled receptor 0.0095 0.7276 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0095 0.7276 1
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Loa Loa (eye worm) G-protein coupled receptor 0.0095 0.7276 0.7018
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0095 0.7276 1
Trichomonas vaginalis tubulin alpha chain, putative 0.0046 0.2712 0.5
Brugia malayi hypothetical protein 0.0095 0.7276 0.7276
Echinococcus granulosus biogenic amine 5HT receptor 0.0095 0.7276 1
Brugia malayi hypothetical protein 0.0095 0.7276 0.7276
Toxoplasma gondii beta tubulin 0.0046 0.2712 1
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0095 0.7276 0.7276
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Onchocerca volvulus 0.0095 0.7276 0.5
Brugia malayi putative neuropeptide receptor NPR1 0.0095 0.7276 0.7276
Brugia malayi Serotonin receptor 0.0095 0.7276 0.7276
Echinococcus granulosus neuropeptides capa receptor 0.0095 0.7276 1
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Leishmania major beta tubulin 0.0046 0.2712 1
Leishmania major beta tubulin 0.0046 0.2712 1
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0095 0.7276 1
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0095 0.7276 1
Echinococcus multilocularis neuropeptide Y receptor 0.0095 0.7276 1
Onchocerca volvulus 0.0095 0.7276 0.5
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0095 0.7276 0.7018
Echinococcus granulosus tm gpcr rhodopsin 0.0095 0.7276 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0095 0.7276 1
Echinococcus granulosus neuropeptide Y receptor 0.0095 0.7276 1
Brugia malayi hypothetical protein 0.0095 0.7276 0.7276
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Echinococcus multilocularis somatostatin receptor 0.0095 0.7276 1
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0095 0.7276 1
Trichomonas vaginalis tubulin epsilon chain, putative 0.0046 0.2712 0.5
Leishmania major beta tubulin 0.0046 0.2712 1
Echinococcus multilocularis serotonin receptor 0.0095 0.7276 1
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0095 0.7276 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0095 0.7276 1
Echinococcus multilocularis neuropeptides capa receptor 0.0095 0.7276 1
Onchocerca volvulus 0.0095 0.7276 0.5
Echinococcus granulosus 7TM GPCR rhodopsin 0.0095 0.7276 1
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Onchocerca volvulus 0.0095 0.7276 0.5
Echinococcus granulosus rhodopsin orphan GPCR 0.0095 0.7276 1
Toxoplasma gondii beta-tubulin, putative 0.0046 0.2712 1
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0095 0.7276 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0095 0.7276 1
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Echinococcus granulosus neuropeptide FF receptor 2 0.0095 0.7276 1
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0095 0.7276 0.7018
Brugia malayi G protein-coupled receptor F59B2.13 0.0095 0.7276 0.7276
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0095 0.7276 0.7276
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0095 0.7276 1
Onchocerca volvulus 0.0095 0.7276 0.5
Echinococcus granulosus rhodopsin orphan GPCR 0.0095 0.7276 1
Loa Loa (eye worm) melatonin receptor type 1A 0.0095 0.7276 0.7018
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Entamoeba histolytica tubulin family protein 0.0046 0.2712 0.5
Brugia malayi Tubulin beta-1 chain 0.0046 0.2712 0.2712
Echinococcus granulosus neuropeptide receptor A26 0.0095 0.7276 1
Echinococcus granulosus G protein coupled receptor 139 0.0095 0.7276 1
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0095 0.7276 1
Brugia malayi hypothetical protein 0.0095 0.7276 0.7276
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0095 0.7276 0.7018
Giardia lamblia Beta tubulin 0.0046 0.2712 0.5
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0095 0.7276 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0095 0.7276 1
Echinococcus granulosus tachykinin peptides receptor 99D 0.0095 0.7276 1
Loa Loa (eye worm) beta-tubulin 0.0046 0.2712 0.202
Leishmania major beta tubulin 0.0046 0.2712 1
Brugia malayi Serotonin receptor 0.0095 0.7276 0.7276
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0095 0.7276 1
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Giardia lamblia Beta tubulin 0.0046 0.2712 0.5
Onchocerca volvulus 0.0095 0.7276 0.5
Echinococcus multilocularis rhodopsin orphan GPCR 0.0095 0.7276 1
Loa Loa (eye worm) tubulin beta-1 chain 0.0046 0.2712 0.202
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0095 0.7276 1
Echinococcus multilocularis fmrfamide receptor 0.0095 0.7276 1
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0095 0.7276 1
Brugia malayi G protein-coupled receptor 0.0095 0.7276 0.7276
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Echinococcus multilocularis allatostatin A receptor 0.0095 0.7276 1
Brugia malayi hypothetical protein 0.0095 0.7276 0.7276
Trypanosoma cruzi beta tubulin, putative 0.0046 0.2712 1
Loa Loa (eye worm) TYRA-2 protein 0.0095 0.7276 0.7018
Brugia malayi G-protein coupled receptor 0.0095 0.7276 0.7276
Trypanosoma brucei beta tubulin 0.0046 0.2712 1
Echinococcus granulosus peptide allatostatin:somatostatin 0.0095 0.7276 1
Loa Loa (eye worm) neuropeptide F receptor 0.0095 0.7276 0.7018
Schistosoma mansoni neuropeptide receptor 0.0095 0.7276 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0095 0.7276 1
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Echinococcus multilocularis rhodopsin orphan GPCR 0.0095 0.7276 1
Brugia malayi sulfakinin receptor protein 0.0095 0.7276 0.7276
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0095 0.7276 1
Echinococcus multilocularis neuropeptide receptor 0.0095 0.7276 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0095 0.7276 1
Brugia malayi beta-tubulin, identical 0.0046 0.2712 0.2712
Brugia malayi ORL1-like opioid receptor 0.0095 0.7276 0.7276
Echinococcus multilocularis g protein coupled receptor 0.0095 0.7276 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0095 0.7276 1
Toxoplasma gondii beta-1 tubulin, putative 0.0046 0.2712 1
Trichomonas vaginalis tubulin gamma chain, putative 0.0046 0.2712 0.5
Echinococcus granulosus g-protein coupled receptor 0.0095 0.7276 1
Schistosoma mansoni opsin-like receptor 0.0095 0.7276 1
Loa Loa (eye worm) BEN-1 protein 0.0046 0.2712 0.202
Onchocerca volvulus Neuropeptide F receptor homolog 0.0095 0.7276 0.5
Brugia malayi Tachykinin-like peptides receptor 99D 0.0095 0.7276 0.7276
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0095 0.7276 1
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Echinococcus multilocularis G protein coupled receptor 139 0.0095 0.7276 1
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Trypanosoma brucei beta tubulin 0.0046 0.2712 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0095 0.7276 1
Schistosoma mansoni neuropeptide F-like receptor 0.0095 0.7276 1
Trichomonas vaginalis tubulin epsilon chain, putative 0.0046 0.2712 0.5
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0095 0.7276 1
Onchocerca volvulus 0.0095 0.7276 0.5
Onchocerca volvulus 0.0095 0.7276 0.5
Brugia malayi Dopamine receptor 0.0095 0.7276 0.7276
Echinococcus multilocularis dro:myosuppressin receptor 0.0095 0.7276 1
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0095 0.7276 0.7018
Echinococcus multilocularis neuropeptide receptor A26 0.0095 0.7276 1
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0095 0.7276 1
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0095 0.7276 0.7276
Echinococcus granulosus biogenic amine 5HT receptor 0.0095 0.7276 1
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Brugia malayi hypothetical protein 0.0095 0.7276 0.7276
Brugia malayi hypothetical protein 0.0095 0.7276 0.7276
Echinococcus multilocularis rhodopsin orphan GPCR 0.0095 0.7276 1
Schistosoma mansoni biogenic amine receptor 0.0095 0.7276 1
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Schistosoma mansoni neuropeptide receptor 0.0095 0.7276 1
Echinococcus granulosus serotonin receptor 0.0095 0.7276 1
Schistosoma mansoni amine GPCR 0.0095 0.7276 1
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Brugia malayi RE15519p 0.0095 0.7276 0.7276
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Echinococcus multilocularis rhodopsin orphan GPCR 0.0095 0.7276 1
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0095 0.7276 1
Onchocerca volvulus 0.0095 0.7276 0.5
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0095 0.7276 1
Brugia malayi neuropeptide F receptor 0.0095 0.7276 0.7276
Plasmodium falciparum tubulin beta chain 0.0046 0.2712 1
Brugia malayi putative neuropeptide receptor 0.0095 0.7276 0.7276
Brugia malayi G-protein coupled receptor 0.0095 0.7276 0.7276
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Entamoeba histolytica tubulin family protein 0.0046 0.2712 0.5
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Echinococcus multilocularis neuropeptide s receptor 0.0095 0.7276 1
Echinococcus multilocularis G-protein coupled receptor, putative 0.0095 0.7276 1
Leishmania major beta tubulin 0.0046 0.2712 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0095 0.7276 1
Leishmania major beta tubulin 0.0046 0.2712 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0095 0.7276 1
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Echinococcus multilocularis sex peptide receptor 0.0095 0.7276 1
Trypanosoma brucei beta tubulin 0.0046 0.2712 1
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0095 0.7276 1
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Schistosoma mansoni amine GPCR 0.0095 0.7276 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0095 0.7276 1
Echinococcus granulosus neuropeptide receptor 0.0095 0.7276 1
Leishmania major beta tubulin 0.0046 0.2712 1
Trichomonas vaginalis tubulin, putative 0.0046 0.2712 0.5
Echinococcus granulosus allatostatin A receptor 0.0095 0.7276 1
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0095 0.7276 1
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Echinococcus granulosus neuropeptides capa receptor 0.0095 0.7276 1
Onchocerca volvulus 0.0095 0.7276 0.5
Schistosoma mansoni neuropeptide receptor 0.0095 0.7276 1
Leishmania major beta tubulin 0.0046 0.2712 1
Onchocerca volvulus 0.0095 0.7276 0.5
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0095 0.7276 1
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0095 0.7276 1
Leishmania major beta tubulin 0.0046 0.2712 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0095 0.7276 1
Brugia malayi hypothetical protein 0.0095 0.7276 0.7276
Schistosoma mansoni amine GPCR 0.0095 0.7276 1
Echinococcus multilocularis neuropeptides capa receptor 0.0095 0.7276 1
Onchocerca volvulus 0.0095 0.7276 0.5
Plasmodium vivax tubulin beta chain, putative 0.0046 0.2712 1
Onchocerca volvulus 0.0095 0.7276 0.5
Echinococcus granulosus tm gpcr rhodopsin 0.0095 0.7276 1
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Schistosoma mansoni neuropeptide receptor 0.0095 0.7276 1
Echinococcus multilocularis neuropeptide Y receptor 0.0095 0.7276 1
Echinococcus granulosus hypothetical protein 0.0095 0.7276 1
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0095 0.7276 0.7018
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0095 0.7276 1
Loa Loa (eye worm) tubulin beta chain 0.0046 0.2712 0.202
Schistosoma mansoni biogenic amine receptor 0.0095 0.7276 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0095 0.7276 1
Schistosoma mansoni hypothetical protein 0.0095 0.7276 1
Echinococcus multilocularis orexin receptor type 2 0.0095 0.7276 1
Brugia malayi Dopamine receptor protein 1 0.0095 0.7276 0.7276
Leishmania major beta tubulin 0.0046 0.2712 1
Onchocerca volvulus 0.0095 0.7276 0.5
Schistosoma mansoni neuropeptide f receptor 76f 0.0095 0.7276 1
Echinococcus granulosus 7tm_1 domain containing protein 0.0095 0.7276 1
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0095 0.7276 0.7276
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0095 0.7276 0.5
Echinococcus multilocularis g protein coupled receptor 0.0095 0.7276 1
Schistosoma mansoni growth hormone secretagogue receptor 0.0095 0.7276 1
Schistosoma mansoni hypothetical protein 0.0095 0.7276 1
Schistosoma mansoni opsin-like receptor 0.0095 0.7276 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0095 0.7276 1
Trichomonas vaginalis tubulin beta chain, putative 0.0046 0.2712 0.5
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0095 0.7276 1
Echinococcus granulosus orexin receptor type 2 0.0095 0.7276 1
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Loa Loa (eye worm) G-protein coupled receptor 0.0095 0.7276 0.7018
Leishmania major beta tubulin 0.0046 0.2712 1
Echinococcus granulosus alpha 1A adrenergic receptor 0.0095 0.7276 1
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0095 0.7276 0.7276
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Echinococcus multilocularis neuropeptide FF receptor 2 0.0095 0.7276 1
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Echinococcus granulosus sex peptide receptor 0.0095 0.7276 1
Brugia malayi hypothetical protein 0.0095 0.7276 0.7276
Echinococcus multilocularis g-protein coupled receptor 0.0095 0.7276 1
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0095 0.7276 1
Echinococcus multilocularis fmrfamide receptor 0.0095 0.7276 1
Echinococcus granulosus neuropeptide receptor 0.0095 0.7276 1
Leishmania major beta tubulin 0.0046 0.2712 1
Echinococcus granulosus neuropeptide s receptor 0.0095 0.7276 1
Schistosoma mansoni histamine h1 receptor 0.0095 0.7276 1
Echinococcus granulosus neuropeptide Y receptor 0.0095 0.7276 1
Loa Loa (eye worm) hypothetical protein 0.0095 0.7276 0.7018
Leishmania major beta tubulin 0.0046 0.2712 1
Schistosoma mansoni myosin xvIII 0.0095 0.7276 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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