Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | TRP transient receptor potential channel | 0.0017 | 0.051 | 0.051 |
Leishmania major | calcium channel protein, putative,ion transporter, putative | 0.0017 | 0.051 | 0.5 |
Echinococcus granulosus | potassium voltage gated channel protein | 0.0017 | 0.051 | 0.051 |
Echinococcus multilocularis | ryanodine receptor 44f | 0.0017 | 0.051 | 0.051 |
Echinococcus granulosus | cyclic nucleotide gated cation channel | 0.0017 | 0.051 | 0.051 |
Echinococcus multilocularis | voltage dependent calcium channel | 0.0017 | 0.051 | 0.051 |
Echinococcus multilocularis | potassium large conductance calcium activated | 0.0017 | 0.051 | 0.051 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.051 | 0.051 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.4113 | 0.4113 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0017 | 0.051 | 0.051 |
Echinococcus granulosus | lamin | 0.0031 | 0.4263 | 0.4263 |
Brugia malayi | Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog | 0.0017 | 0.051 | 0.0076 |
Echinococcus granulosus | voltage gated sodium channel Nav1 alpha subunit | 0.0017 | 0.051 | 0.051 |
Loa Loa (eye worm) | ion channel NompC | 0.0017 | 0.051 | 0.051 |
Echinococcus granulosus | hypothetical protein | 0.0017 | 0.051 | 0.051 |
Echinococcus granulosus | voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 | 0.0017 | 0.051 | 0.051 |
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.0017 | 0.051 | 0.051 |
Echinococcus multilocularis | voltage dependent calcium channel type d subunit | 0.0017 | 0.051 | 0.051 |
Schistosoma mansoni | transient receptor potential channel | 0.0017 | 0.0511 | 0.0000024361 |
Echinococcus multilocularis | voltage dependent L type calcium channel subunit | 0.0017 | 0.051 | 0.051 |
Toxoplasma gondii | transporter, cation channel family protein | 0.0017 | 0.051 | 0.5 |
Echinococcus multilocularis | calcium activated potassium channel | 0.0017 | 0.051 | 0.051 |
Echinococcus granulosus | hyperpolarization activated cyclic | 0.0017 | 0.051 | 0.051 |
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.0017 | 0.051 | 0.051 |
Brugia malayi | Voltage-gated calcium channel, alpha subunit | 0.0017 | 0.051 | 0.0076 |
Echinococcus multilocularis | voltage dependent L type calcium channel subunit | 0.0017 | 0.051 | 0.051 |
Loa Loa (eye worm) | voltage-gated calcium channel | 0.0017 | 0.051 | 0.051 |
Echinococcus granulosus | potassium voltage gated channel subfamily D | 0.0017 | 0.051 | 0.051 |
Echinococcus granulosus | short transient receptor potential channel 6 | 0.0017 | 0.051 | 0.051 |
Echinococcus granulosus | potassium voltage gated channel protein | 0.0017 | 0.051 | 0.051 |
Echinococcus granulosus | voltage gated potassium channel | 0.0017 | 0.051 | 0.051 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.051 | 0.051 |
Echinococcus multilocularis | hyperpolarization activated cyclic | 0.0017 | 0.051 | 0.051 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0017 | 0.051 | 0.051 |
Toxoplasma gondii | transporter, cation channel family protein | 0.0017 | 0.051 | 0.5 |
Echinococcus granulosus | sodium leak channel non selective protein | 0.0017 | 0.051 | 0.051 |
Schistosoma mansoni | intermediate filament proteins | 0.0031 | 0.4263 | 0.3955 |
Schistosoma mansoni | transient receptor potential channel | 0.0017 | 0.0511 | 0.0000024361 |
Brugia malayi | Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog | 0.0017 | 0.051 | 0.0076 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.051 | 0.051 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0017 | 0.051 | 0.051 |
Echinococcus multilocularis | sodium channel protein | 0.0017 | 0.051 | 0.051 |
Onchocerca volvulus | 0.0031 | 0.4263 | 1 | |
Trypanosoma brucei | inositol 1,4,5-trisphosphate receptor | 0.0017 | 0.051 | 0.5 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0017 | 0.0511 | 0.0511 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0017 | 0.0511 | 0.0511 |
Echinococcus multilocularis | sodium leak channel non selective protein | 0.0017 | 0.051 | 0.051 |
Loa Loa (eye worm) | calcium channel | 0.0017 | 0.051 | 0.051 |
Echinococcus multilocularis | transfer RNA-Gly | 0.0017 | 0.051 | 0.051 |
Echinococcus granulosus | lamin dm0 | 0.0031 | 0.4263 | 0.4263 |
Onchocerca volvulus | 0.0031 | 0.4263 | 1 | |
Toxoplasma gondii | transporter, cation channel family protein | 0.0017 | 0.051 | 0.5 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0017 | 0.051 | 0.051 |
Leishmania major | hypothetical protein, unknown function | 0.0017 | 0.051 | 0.5 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0017 | 0.051 | 0.051 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0017 | 0.051 | 0.051 |
Echinococcus granulosus | intermediate filament protein | 0.0031 | 0.4263 | 0.4263 |
Echinococcus granulosus | potassium voltage gated channel protein | 0.0017 | 0.051 | 0.051 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0017 | 0.051 | 0.5 |
Toxoplasma gondii | hypothetical protein | 0.0017 | 0.051 | 0.5 |
Echinococcus multilocularis | potassium voltage gated channel subfamily D | 0.0017 | 0.051 | 0.051 |
Schistosoma mansoni | lamin | 0.0031 | 0.4263 | 0.3955 |
Brugia malayi | Cyclic-nucleotide gated cation channel | 0.0017 | 0.051 | 0.0076 |
Echinococcus multilocularis | hyperpolarization activated cyclic | 0.0017 | 0.051 | 0.051 |
Leishmania major | hypothetical protein, conserved | 0.0017 | 0.051 | 0.5 |
Brugia malayi | Ryanodine Receptor TM 4-6 family protein | 0.0017 | 0.051 | 0.0076 |
Echinococcus granulosus | transient receptor potential gamma protein | 0.0017 | 0.051 | 0.051 |
Echinococcus multilocularis | voltage gated potassium channel | 0.0017 | 0.051 | 0.051 |
Echinococcus granulosus | two pore calcium channel protein 1 | 0.0017 | 0.051 | 0.051 |
Loa Loa (eye worm) | ryanodine receptor | 0.0017 | 0.051 | 0.051 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0017 | 0.051 | 0.0076 |
Echinococcus multilocularis | voltage gated hydrogen channel 1 | 0.0017 | 0.051 | 0.051 |
Schistosoma mansoni | lamin | 0.0031 | 0.4263 | 0.3955 |
Echinococcus multilocularis | voltage dependent calcium channel type d subunit | 0.0017 | 0.051 | 0.051 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0017 | 0.0511 | 0.0511 |
Echinococcus granulosus | voltage dependent L type calcium channel subunit|voltage dependent calcium channel | 0.0017 | 0.051 | 0.051 |
Echinococcus granulosus | two pore calcium channel protein 2 | 0.0017 | 0.051 | 0.051 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0511 | 0.0511 |
Brugia malayi | Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog | 0.0017 | 0.051 | 0.0076 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0017 | 0.051 | 0.5 |
Brugia malayi | Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit | 0.0017 | 0.051 | 0.0076 |
Echinococcus granulosus | potassium voltage gated channel protein | 0.0017 | 0.051 | 0.051 |
Echinococcus granulosus | shaker cognate | 0.0017 | 0.051 | 0.051 |
Echinococcus multilocularis | potassium voltage gated channel protein | 0.0017 | 0.051 | 0.051 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.051 | 0.051 |
Echinococcus multilocularis | potassium voltage gated channel subfamily D | 0.0017 | 0.051 | 0.051 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0017 | 0.051 | 0.051 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0511 | 0.0511 |
Brugia malayi | Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit | 0.0017 | 0.051 | 0.0076 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0031 | 0.4263 | 0.4263 |
Echinococcus multilocularis | two pore calcium channel protein 1 | 0.0017 | 0.051 | 0.051 |
Echinococcus multilocularis | potassium voltage gated channel protein | 0.0017 | 0.051 | 0.051 |
Echinococcus granulosus | potassium voltage gated channel subfamily C | 0.0017 | 0.051 | 0.051 |
Echinococcus multilocularis | lamin dm0 | 0.0031 | 0.4263 | 0.4263 |
Echinococcus granulosus | potassium voltage gated channel subfamily D | 0.0017 | 0.051 | 0.051 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.051 | 0.051 |
Echinococcus granulosus | potassium voltage gated channel protein | 0.0017 | 0.051 | 0.051 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0017 | 0.051 | 0.5 |
Brugia malayi | Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog | 0.0017 | 0.051 | 0.0076 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.051 | 0.051 |
Echinococcus multilocularis | transient receptor potential gamma protein | 0.0017 | 0.051 | 0.051 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0017 | 0.0511 | 0.0511 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.051 | 0.051 |
Echinococcus granulosus | potassium voltage gated channel subfamily D | 0.0017 | 0.051 | 0.051 |
Echinococcus granulosus | voltage gated potassium channel | 0.0017 | 0.051 | 0.051 |
Echinococcus granulosus | calcium activated potassium channel | 0.0017 | 0.051 | 0.051 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0031 | 0.4263 | 0.4001 |
Echinococcus granulosus | voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu | 0.0017 | 0.051 | 0.051 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0017 | 0.0511 | 0.0511 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0017 | 0.051 | 0.051 |
Echinococcus multilocularis | musashi | 0.0031 | 0.4263 | 0.4263 |
Trypanosoma cruzi | Voltage-dependent calcium channel subunit, putative | 0.0017 | 0.051 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.051 | 0.051 |
Echinococcus granulosus | voltage dependent calcium channel | 0.0017 | 0.051 | 0.051 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.051 | 0.051 |
Echinococcus multilocularis | potassium voltage gated channel protein | 0.0017 | 0.051 | 0.051 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0016 | 0.0438 | 0.0438 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0017 | 0.0511 | 0.0511 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.051 | 0.051 |
Brugia malayi | Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog | 0.0017 | 0.051 | 0.0076 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0017 | 0.051 | 0.051 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.051 | 0.051 |
Echinococcus granulosus | short transient receptor potential channel 6 | 0.0017 | 0.051 | 0.051 |
Loa Loa (eye worm) | intermediate filament protein | 0.0031 | 0.4263 | 0.4263 |
Echinococcus multilocularis | two pore calcium channel protein 2 | 0.0017 | 0.051 | 0.051 |
Echinococcus granulosus | voltage gated hydrogen channel 1 | 0.0017 | 0.051 | 0.051 |
Echinococcus multilocularis | voltage dependent calcium channel | 0.0017 | 0.051 | 0.051 |
Brugia malayi | Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog | 0.0017 | 0.051 | 0.0076 |
Loa Loa (eye worm) | voltage-gated potassium channel | 0.0017 | 0.051 | 0.051 |
Trypanosoma cruzi | inositol 1,4,5-trisphosphate receptor, putative | 0.0017 | 0.051 | 0.5 |
Echinococcus multilocularis | cyclic nucleotide gated cation channel | 0.0017 | 0.051 | 0.051 |
Brugia malayi | Transient-receptor-potential like protein | 0.0017 | 0.051 | 0.0076 |
Brugia malayi | ion channel NompC | 0.0017 | 0.051 | 0.0076 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.051 | 0.051 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.051 | 0.051 |
Echinococcus multilocularis | potassium voltage gated channel subfamily D | 0.0017 | 0.051 | 0.051 |
Echinococcus multilocularis | TRP (transient receptor potential) channel | 0.0017 | 0.051 | 0.051 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0017 | 0.051 | 0.5 |
Echinococcus granulosus | potassium large conductance calcium activated | 0.0017 | 0.051 | 0.051 |
Loa Loa (eye worm) | voltage-gated potassium channel | 0.0017 | 0.051 | 0.051 |
Echinococcus granulosus | ryanodine receptor 44f | 0.0017 | 0.051 | 0.051 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.051 | 0.051 |
Brugia malayi | Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog | 0.0017 | 0.051 | 0.0076 |
Echinococcus granulosus | hyperpolarization activated cyclic | 0.0017 | 0.051 | 0.051 |
Brugia malayi | Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit | 0.0017 | 0.051 | 0.0076 |
Loa Loa (eye worm) | cyclic-nucleotide gated cation channel | 0.0017 | 0.051 | 0.051 |
Echinococcus granulosus | cyclic nucleotide gated cation channel alpha 3 | 0.0017 | 0.051 | 0.051 |
Echinococcus multilocularis | potassium voltage gated channel subfamily C | 0.0017 | 0.051 | 0.051 |
Brugia malayi | voltage-dependent calcium channel | 0.0017 | 0.051 | 0.0076 |
Echinococcus multilocularis | shaker cognate | 0.0017 | 0.051 | 0.051 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.051 | 0.051 |
Brugia malayi | Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog | 0.0017 | 0.051 | 0.0076 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0017 | 0.051 | 0.051 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.051 | 0.051 |
Echinococcus granulosus | potassium:sodium hyperpolarization activated | 0.0017 | 0.051 | 0.051 |
Trypanosoma brucei | Voltage-dependent calcium channel subunit, putative | 0.0017 | 0.051 | 0.5 |
Brugia malayi | intermediate filament protein | 0.0031 | 0.4263 | 0.4001 |
Echinococcus multilocularis | potassium:sodium hyperpolarization activated | 0.0017 | 0.051 | 0.051 |
Echinococcus granulosus | potassium voltage gated channel subfamily A | 0.0017 | 0.051 | 0.051 |
Brugia malayi | cation channel family protein | 0.0017 | 0.051 | 0.0076 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0511 | 0.0511 |
Echinococcus multilocularis | lamin | 0.0031 | 0.4263 | 0.4263 |
Echinococcus multilocularis | cyclic nucleotide gated cation channel alpha 3 | 0.0017 | 0.051 | 0.051 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.051 | 0.051 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.051 | 0.051 |
Brugia malayi | hypothetical protein | 0.0017 | 0.051 | 0.0076 |
Echinococcus multilocularis | conserved hypothetical protein | 0.0017 | 0.051 | 0.051 |
Echinococcus granulosus | Potassium voltage gated channel protein Shaw | 0.0017 | 0.051 | 0.051 |
Echinococcus multilocularis | potassium voltage gated channel subfamily A | 0.0017 | 0.051 | 0.051 |
Brugia malayi | Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit | 0.0017 | 0.051 | 0.0076 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0017 | 0.051 | 0.051 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.051 | 0.051 |
Echinococcus multilocularis | potassium voltage gated channel protein | 0.0017 | 0.051 | 0.051 |
Echinococcus granulosus | cyclic nucleotide gated cation channel | 0.0017 | 0.051 | 0.051 |
Echinococcus multilocularis | potassium voltage gated channel subfamily KQT | 0.0017 | 0.051 | 0.051 |
Brugia malayi | olfactory channel protein osm-9 | 0.0017 | 0.0511 | 0.0076 |
Echinococcus multilocularis | voltage gated potassium channel | 0.0017 | 0.051 | 0.051 |
Echinococcus granulosus | voltage dependent calcium channel | 0.0017 | 0.051 | 0.051 |
Loa Loa (eye worm) | cyclic-nucleotide gated cation channel | 0.0017 | 0.051 | 0.051 |
Brugia malayi | cation channel family protein | 0.0017 | 0.051 | 0.0076 |
Echinococcus granulosus | sodium channel protein | 0.0017 | 0.051 | 0.051 |
Echinococcus granulosus | potassium channel KvQLT family member kqt 1 | 0.0017 | 0.051 | 0.051 |
Loa Loa (eye worm) | voltage-dependent calcium channel | 0.0017 | 0.051 | 0.051 |
Toxoplasma gondii | hypothetical protein | 0.0017 | 0.051 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.4263 | 0.4263 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.