Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | serine/threonine protein kinase | 0.0185 | 0.157 | 0.157 |
Giardia lamblia | Kinase, PLK | 0.0185 | 0.157 | 0.5 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0185 | 0.157 | 0.0306 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0169 | 0.1304 | 0.2757 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0329 | 0.4058 | 0.3167 |
Brugia malayi | cathepsin L-like precursor | 0.022 | 0.218 | 0.5061 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0185 | 0.157 | 0.0967 |
Leishmania major | cathepsin L-like protease | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0329 | 0.4058 | 1 |
Onchocerca volvulus | 0.0329 | 0.4058 | 1 | |
Onchocerca volvulus | 0.0329 | 0.4058 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0329 | 0.4058 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.022 | 0.218 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.022 | 0.218 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Onchocerca volvulus | 0.022 | 0.218 | 0.2452 | |
Trypanosoma cruzi | cysteine protease, putative | 0.0169 | 0.1304 | 0.2757 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0185 | 0.157 | 0.0967 |
Loa Loa (eye worm) | ctsf protein | 0.0329 | 0.4058 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0329 | 0.4058 | 0.3167 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0329 | 0.4058 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Leishmania major | cathepsin L-like protease | 0.0329 | 0.4058 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0329 | 0.4058 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0329 | 0.4058 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0329 | 0.4058 | 1 |
Plasmodium vivax | unspecified product | 0.0169 | 0.1304 | 0.2757 |
Onchocerca volvulus | 0.0329 | 0.4058 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.022 | 0.218 | 0.5061 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0329 | 0.4058 | 0.4058 |
Loa Loa (eye worm) | hypothetical protein | 0.022 | 0.218 | 0.5061 |
Leishmania major | cathepsin L-like protease | 0.0329 | 0.4058 | 1 |
Leishmania major | cathepsin L-like protease | 0.0329 | 0.4058 | 1 |
Leishmania major | cathepsin L-like protease | 0.0329 | 0.4058 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0169 | 0.1304 | 0.1304 |
Entamoeba histolytica | cysteine protease, putative | 0.0329 | 0.4058 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0169 | 0.1304 | 0.2757 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0185 | 0.157 | 0.3457 |
Onchocerca volvulus | 0.0329 | 0.4058 | 1 | |
Entamoeba histolytica | cysteine proteinase, putative | 0.022 | 0.218 | 0.3182 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0185 | 0.157 | 0.0967 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0185 | 0.157 | 0.0967 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0329 | 0.4058 | 0.3167 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.022 | 0.218 | 0.218 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0329 | 0.4058 | 1 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0185 | 0.157 | 0.0306 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0329 | 0.4058 | 0.3167 |
Onchocerca volvulus | Cathepsin L homolog | 0.0329 | 0.4058 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0329 | 0.4058 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0329 | 0.4058 | 1 |
Loa Loa (eye worm) | fibroinase | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Schistosoma mansoni | cathepsin s | 0.0109 | 0.0255 | 0.0255 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0169 | 0.1304 | 0.2757 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0329 | 0.4058 | 0.3167 |
Brugia malayi | Cathepsin L-like precursor | 0.0329 | 0.4058 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0329 | 0.4058 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0329 | 0.4058 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0329 | 0.4058 | 1 |
Leishmania major | cathepsin L-like protease | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0329 | 0.4058 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0329 | 0.4058 | 1 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0185 | 0.157 | 0.3457 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0185 | 0.157 | 0.0967 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0185 | 0.157 | 0.0967 |
Onchocerca volvulus | 0.0329 | 0.4058 | 1 | |
Echinococcus multilocularis | cysteine protease | 0.0329 | 0.4058 | 0.3167 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0169 | 0.1304 | 0.1304 |
Onchocerca volvulus | 0.0329 | 0.4058 | 1 | |
Plasmodium vivax | vivapain-3 | 0.0169 | 0.1304 | 0.2757 |
Toxoplasma gondii | cathepsin CPL | 0.0329 | 0.4058 | 0.5 |
Plasmodium vivax | vivapain-1 | 0.0169 | 0.1304 | 0.2757 |
Loa Loa (eye worm) | cysteine protease | 0.0329 | 0.4058 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0329 | 0.4058 | 1 |
Onchocerca volvulus | 0.0329 | 0.4058 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0185 | 0.157 | 0.0967 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0329 | 0.4058 | 0.4058 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0329 | 0.4058 | 0.3167 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0329 | 0.4058 | 1 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0185 | 0.157 | 0.3457 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0329 | 0.4058 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0329 | 0.4058 | 1 |
Plasmodium vivax | vivapain-2 | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0329 | 0.4058 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0329 | 0.4058 | 1 |
Leishmania major | cathepsin L-like protease | 0.0329 | 0.4058 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0329 | 0.4058 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.022 | 0.218 | 0.5061 |
Brugia malayi | Cathepsin L-like precursor | 0.022 | 0.218 | 0.5061 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0185 | 0.157 | 0.0967 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0169 | 0.1304 | 0.2757 |
Brugia malayi | Cathepsin L-like precursor | 0.022 | 0.218 | 0.5061 |
Onchocerca volvulus | Cathepsin F homolog | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0329 | 0.4058 | 1 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0169 | 0.1304 | 0.2757 |
Brugia malayi | Cathepsin L-like precursor | 0.0329 | 0.4058 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.022 | 0.218 | 0.1008 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.022 | 0.218 | 0.5061 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0329 | 0.4058 | 0.3167 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0185 | 0.157 | 0.3457 |
Brugia malayi | Cathepsin L-like precursor | 0.0329 | 0.4058 | 1 |
Plasmodium vivax | vivapain-2 | 0.0329 | 0.4058 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0329 | 0.4058 | 0.3167 |
Leishmania major | cathepsin L-like protease | 0.0329 | 0.4058 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0329 | 0.4058 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0329 | 0.4058 | 1 |
Trypanosoma brucei | polo-like protein kinase | 0.0185 | 0.157 | 0.0967 |
Leishmania major | cysteine peptidase A (CPA) | 0.0329 | 0.4058 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0169 | 0.1304 | 0.1304 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0329 | 0.4058 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.022 | 0.218 | 0.5061 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0169 | 0.1304 | 0.2757 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.