Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | ubiquitin specific protease 41 | 0.0078 | 0.066 | 0.061 |
Mycobacterium tuberculosis | Probable multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0164 | 0.1711 | 0.6776 |
Schistosoma mansoni | ubiquitin-specific peptidase 8 (C19 family) | 0.0078 | 0.066 | 0.3355 |
Mycobacterium ulcerans | 3-oxoacyl-(acyl carrier protein) synthase II | 0.0039 | 0.0184 | 0.0017 |
Mycobacterium ulcerans | polyketide synthase | 0.0164 | 0.1711 | 0.6528 |
Leishmania major | beta-ketoacyl synthase family protein, putative,3-oxoacyl-acyl carrier protein synthase ii, putative | 0.0039 | 0.0184 | 0.1766 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.066 | 0.2296 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0039 | 0.018 | 0.07 |
Echinococcus multilocularis | dna polymerase eta | 0.0041 | 0.0206 | 0.0154 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.0515 | 0.2553 |
Brugia malayi | oxidoreductase, zinc-binding dehydrogenase family protein | 0.0293 | 0.328 | 1 |
Mycobacterium ulcerans | thioesterase | 0.0129 | 0.128 | 0.4691 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0206 | 0.253 |
Echinococcus granulosus | dna polymerase kappa | 0.0041 | 0.0206 | 0.0846 |
Mycobacterium ulcerans | polyketide synthase | 0.0155 | 0.1594 | 0.603 |
Echinococcus granulosus | dna polymerase eta | 0.0041 | 0.0206 | 0.0846 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0206 | 0.253 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0292 | 0.1318 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.0292 | 0.1318 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0039 | 0.018 | 0.1698 |
Mycobacterium ulcerans | polyketide synthase MbtD | 0.0048 | 0.029 | 0.047 |
Schistosoma mansoni | methyltransferase-related | 0.0047 | 0.0278 | 0.1245 |
Loa Loa (eye worm) | RNA binding protein | 0.0066 | 0.0515 | 0.1791 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.0515 | 0.2553 |
Leishmania major | hypothetical protein, conserved | 0.0047 | 0.0278 | 0.3402 |
Mycobacterium tuberculosis | Polyketide synthetase MbtC (polyketide synthase) | 0.0053 | 0.0358 | 0.1419 |
Echinococcus granulosus | 3 oxoacyl acyl carrier protein synthase | 0.0039 | 0.0184 | 0.0721 |
Loa Loa (eye worm) | fatty acid synthase | 0.0153 | 0.1569 | 0.5459 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0053 | 0.0186 |
Toxoplasma gondii | 3-oxoacyl-acyl-carrier protein synthase I/II, putative | 0.0039 | 0.0184 | 0.1074 |
Brugia malayi | hypothetical protein | 0.0038 | 0.0168 | 0.0354 |
Trypanosoma brucei | unspecified product | 0.0041 | 0.0206 | 0.253 |
Trypanosoma brucei | beta-ketoacyl-ACP synthase | 0.0039 | 0.0184 | 0.2159 |
Schistosoma mansoni | inositol monophosphatase | 0.0039 | 0.018 | 0.07 |
Giardia lamblia | Methyltransferase like 2 | 0.0047 | 0.0278 | 0.1589 |
Mycobacterium leprae | Polyketide synthase Pks13 | 0.0231 | 0.2525 | 1 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0041 | 0.0206 | 0.0817 |
Brugia malayi | Inositol-1 | 0.0039 | 0.018 | 0.0392 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE | 0.0102 | 0.0956 | 0.3787 |
Wolbachia endosymbiont of Brugia malayi | 3-oxoacyl-ACP synthase | 0.0039 | 0.0184 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0048 | 0.029 | 0.0734 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0041 | 0.0206 | 0.0154 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0041 | 0.0206 | 0.0785 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.0515 | 0.2553 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0047 | 0.0278 | 0.0573 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0155 | 0.1594 | 0.6312 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0082 | 0.0284 |
Mycobacterium tuberculosis | Probable fatty acid synthase Fas (fatty acid synthetase) | 0.0049 | 0.0303 | 0.1198 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.0515 | 0.2553 |
Mycobacterium ulcerans | thioesterase TesA | 0.0129 | 0.128 | 0.4691 |
Schistosoma mansoni | DNA polymerase eta | 0.0041 | 0.0206 | 0.0846 |
Mycobacterium ulcerans | polyketide synthase Pks9 | 0.0102 | 0.0956 | 0.3311 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks9 | 0.0088 | 0.0782 | 0.3095 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0155 | 0.1594 | 0.603 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsB | 0.0124 | 0.1226 | 0.4461 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC | 0.0164 | 0.1711 | 0.6776 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0041 | 0.0206 | 0.2156 |
Brugia malayi | hypothetical protein | 0.003 | 0.0082 | 0.0088 |
Mycobacterium ulcerans | fatty acid synthase Fas | 0.0049 | 0.0303 | 0.0524 |
Schistosoma mansoni | hypothetical protein | 0.0177 | 0.1861 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0038 | 0.0168 | 0.0632 |
Loa Loa (eye worm) | TAR-binding protein | 0.0066 | 0.0515 | 0.1791 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0038 | 0.0168 | 0.0115 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0041 | 0.0206 | 0.2156 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0041 | 0.0206 | 0.0154 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0041 | 0.0206 | 0.2156 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0206 | 0.253 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0766 | 0.2665 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0041 | 0.0206 | 0.2156 |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.0039 | 0.0184 | 0.0404 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB | 0.0124 | 0.1226 | 0.4856 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0041 | 0.0206 | 0.0846 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0155 | 0.1594 | 0.6312 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0041 | 0.0206 | 0.0846 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0038 | 0.0168 | 0.0632 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0155 | 0.1594 | 0.6312 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0206 | 0.253 |
Echinococcus multilocularis | 3 oxoacyl (acyl carrier protein) synthase | 0.0039 | 0.0184 | 0.0131 |
Echinococcus multilocularis | dna polymerase kappa | 0.0041 | 0.0206 | 0.0154 |
Mycobacterium tuberculosis | Polyketide synthase Pks12 | 0.0164 | 0.1711 | 0.6776 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0039 | 0.018 | 0.0247 |
Giardia lamblia | Ubiquitin carboxyl-terminal hydrolase 4 | 0.0078 | 0.066 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0066 | 0.0515 | 0.2553 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.0292 | 0.0239 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0039 | 0.018 | 0.1698 |
Mycobacterium ulcerans | 3-oxoacyl-(acyl carrier protein) synthase II | 0.0039 | 0.0184 | 0.0017 |
Schistosoma mansoni | inositol monophosphatase | 0.0039 | 0.018 | 0.07 |
Onchocerca volvulus | Fatty acid synthase homolog | 0.0279 | 0.3105 | 1 |
Loa Loa (eye worm) | inositol-1 | 0.0039 | 0.018 | 0.0626 |
Mycobacterium leprae | PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) | 0.0049 | 0.0303 | 0.1198 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0041 | 0.0206 | 0.253 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0292 | 0.1318 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0078 | 0.066 | 0.2791 |
Mycobacterium tuberculosis | Probable thioesterase TesA | 0.0129 | 0.128 | 0.5069 |
Trypanosoma cruzi | beta-ketoacyl synthase family protein, putative | 0.0039 | 0.0184 | 0.1766 |
Trypanosoma brucei | ubiquitin carboxyl-terminal hydrolase, putative | 0.0078 | 0.066 | 1 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0078 | 0.066 | 1 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0041 | 0.0206 | 0.2156 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0155 | 0.1594 | 0.603 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0048 | 0.0292 | 0.1014 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0145 | 0.147 | 0.5823 |
Mycobacterium leprae | PROBABLE THIOESTERASE TESA | 0.0129 | 0.128 | 0.5069 |
Mycobacterium tuberculosis | Polyketide synthetase MbtD (polyketide synthase) | 0.0048 | 0.029 | 0.1149 |
Mycobacterium leprae | Probable polyketide synthase Pks1 | 0.0164 | 0.1711 | 0.6776 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0041 | 0.0206 | 0.0113 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0206 | 0.253 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0047 | 0.0278 | 0.1102 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0078 | 0.0663 | 0.3874 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks5 | 0.015 | 0.1536 | 0.6084 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0164 | 0.1711 | 0.6528 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0041 | 0.0206 | 0.0113 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0041 | 0.0206 | 0.253 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.003 | 0.0082 | 0.0478 |
Plasmodium vivax | 3-oxoacyl-[acyl-carrier-protein] synthase i/ii, putative | 0.0039 | 0.0184 | 1 |
Loa Loa (eye worm) | intermediate filament protein | 0.0028 | 0.0053 | 0.0186 |
Echinococcus granulosus | ubiquitin carboxyl terminal hydrolase 8 | 0.0078 | 0.066 | 0.3355 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0155 | 0.1594 | 0.603 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0039 | 0.018 | 0.0127 |
Mycobacterium leprae | Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas | 0.0164 | 0.1711 | 0.6776 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0041 | 0.0206 | 0.2156 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0047 | 0.0164 |
Chlamydia trachomatis | 3-oxoacyl-ACP synthase | 0.0039 | 0.0184 | 0.5 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0066 | 0.0515 | 0.1791 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0028 | 0.0053 | 0.0186 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0292 | 0.1318 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0041 | 0.0206 | 0.253 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks15 | 0.0063 | 0.0473 | 0.1871 |
Echinococcus granulosus | ubiquitin specific protease 41 | 0.0078 | 0.066 | 0.3355 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.0292 | 0.0239 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0048 | 0.0292 | 0.0738 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0164 | 0.1711 | 1 |
Schistosoma mansoni | 3-oxoacyl-[ACP] synthase | 0.0039 | 0.0184 | 0.0721 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0041 | 0.0206 | 0.253 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0041 | 0.0206 | 0.0474 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0034 | 0.0131 | 0.0518 |
Mycobacterium tuberculosis | Probable membrane bound polyketide synthase Pks6 | 0.0231 | 0.2525 | 1 |
Mycobacterium tuberculosis | Polyketide synthase Pks13 | 0.0231 | 0.2525 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.026 | 0.2874 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0185 | 0.1962 | 0.6825 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks17 | 0.0038 | 0.0171 | 0.0678 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.003 | 0.0082 | 0.0477 |
Brugia malayi | TAR-binding protein | 0.0066 | 0.0515 | 0.143 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0039 | 0.018 | 0.1698 |
Loa Loa (eye worm) | acyl carrier protein | 0.0071 | 0.0577 | 0.2007 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0206 | 0.253 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.0292 | 0.1318 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0078 | 0.066 | 1 |
Echinococcus granulosus | Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 | 0.0078 | 0.066 | 0.3355 |
Trichomonas vaginalis | conserved hypothetical protein | 0.018 | 0.19 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0206 | 0.253 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0078 | 0.066 | 0.2791 |
Loa Loa (eye worm) | beta-ketoacyl synthase domain-containing protein | 0.0039 | 0.0184 | 0.0639 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD | 0.0155 | 0.1594 | 0.6312 |
Plasmodium falciparum | 3-oxoacyl-acyl-carrier protein synthase I/II | 0.0039 | 0.0184 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0047 | 0.0278 | 0.1102 |
Toxoplasma gondii | beta-ketoacyl synthase, N-terminal domain-containing protein | 0.01 | 0.0933 | 0.5451 |
Mycobacterium ulcerans | multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0164 | 0.1711 | 0.6528 |
Brugia malayi | Ubiquitin carboxyl-terminal hydrolase family protein | 0.0078 | 0.066 | 0.188 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks8 | 0.0127 | 0.1251 | 0.4954 |
Leishmania major | ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative | 0.0078 | 0.066 | 1 |
Echinococcus multilocularis | Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 | 0.0078 | 0.066 | 0.061 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.0515 | 0.2553 |
Mycobacterium ulcerans | polyketide synthase MbtC | 0.0039 | 0.0184 | 0.0017 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0206 | 0.253 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0034 | 0.0131 | 0.0518 |
Echinococcus multilocularis | ubiquitin carboxyl terminal hydrolase 8 | 0.0078 | 0.066 | 0.061 |
Trypanosoma cruzi | beta-ketoacyl synthase family protein, putative | 0.0039 | 0.0184 | 0.1766 |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.0155 | 0.1594 | 0.4775 |
Onchocerca volvulus | 0.0145 | 0.147 | 0.4643 | |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0206 | 0.0718 |
Schistosoma mansoni | ubiquitin-specific peptidase 2 (C19 family) | 0.0078 | 0.066 | 0.3355 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0039 | 0.018 | 0.2094 |
Brugia malayi | RNA binding protein | 0.0066 | 0.0515 | 0.143 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0041 | 0.0206 | 0.0474 |
Leishmania major | DNA polymerase kappa, putative | 0.0041 | 0.0206 | 0.2156 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0145 | 0.147 | 0.5116 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0041 | 0.0206 | 0.0817 |
Echinococcus granulosus | geminin | 0.0177 | 0.1861 | 1 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0039 | 0.018 | 0.1051 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.0168 | 0.0632 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0124 | 0.1226 | 0.4461 |
Mycobacterium ulcerans | polyketide synthase Pks13 | 0.0231 | 0.2525 | 1 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks1 | 0.0111 | 0.1064 | 0.4212 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0041 | 0.0206 | 0.0718 |
Brugia malayi | AMP-binding enzyme family protein | 0.0145 | 0.147 | 0.4392 |
Mycobacterium tuberculosis | Polyketide synthase Pks2 | 0.015 | 0.1536 | 0.6084 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsE | 0.0102 | 0.0956 | 0.3311 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0041 | 0.0206 | 0.0154 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.011 | 0.1052 | 0.6145 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0206 | 0.253 |
Entamoeba histolytica | ubiquitin carboxyl-terminal hydrolase domain containing protein | 0.0078 | 0.066 | 1 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks7 | 0.0164 | 0.1711 | 0.6776 |
Leishmania major | DNA polymerase eta, putative | 0.0041 | 0.0206 | 0.2156 |
Echinococcus multilocularis | geminin | 0.0177 | 0.1861 | 0.1818 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0206 | 0.253 |
Brugia malayi | Methyltransferase-like protein 4 | 0.0047 | 0.0278 | 0.0697 |
Schistosoma mansoni | hypothetical protein | 0.0177 | 0.1861 | 1 |
Brugia malayi | Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog | 0.0185 | 0.1962 | 0.5914 |
Echinococcus multilocularis | tar DNA binding protein | 0.0066 | 0.0515 | 0.0464 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA | 0.0155 | 0.1594 | 0.6312 |
Onchocerca volvulus | 0.0269 | 0.2988 | 0.9617 | |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0041 | 0.0206 | 0.0846 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0066 | 0.0515 | 0.143 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0078 | 0.066 | 0.2791 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0155 | 0.1594 | 0.603 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (binding) | Induction of HEXIM1 protein expression in human LNCAP cells after 24 hrs by Western blotting analysis | ChEMBL. | 24503105 | |
FC (binding) | = 1.23 | Induction of HEXIM1 protein expression in human LNCAP cells at 100 uM after 24 hrs by Western blotting analysis relative to control | ChEMBL. | 24503105 |
FC (binding) | = 4.89 | Induction of HEXIM1 protein expression in human LNCAP cells at 500 uM after 24 hrs by Western blotting analysis relative to control | ChEMBL. | 24503105 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.