Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium vivax | vivapain-2 | 0.0026 | 0.0626 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0013 | 0.0225 | 0.3058 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0073 | 0.0108 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0098 | 0.2948 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0013 | 0.0225 | 0.0225 |
Mycobacterium tuberculosis | Possible cytochrome P450 135A1 Cyp135A1 | 0.0031 | 0.0785 | 1 |
Mycobacterium ulcerans | cytochrome P450 191A3 Cyp191A3 | 0.0031 | 0.0785 | 0.472 |
Brugia malayi | Cytochrome P450 family protein | 0.0058 | 0.1662 | 0.2854 |
Plasmodium vivax | unspecified product | 0.0013 | 0.0225 | 0.2757 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.0208 | 0.0208 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0031 | 0.0785 | 0.2477 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0017 | 0.0352 | 0.0352 |
Onchocerca volvulus | 0.0026 | 0.0626 | 0.1341 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.0626 | 0.8502 |
Onchocerca volvulus | Cathepsin L homolog | 0.0026 | 0.0626 | 0.1341 |
Toxoplasma gondii | cathepsin CPL | 0.0026 | 0.0626 | 0.5291 |
Onchocerca volvulus | 0.0026 | 0.0626 | 0.1341 | |
Entamoeba histolytica | cysteine proteinase, putative | 0.0013 | 0.0225 | 0.1308 |
Brugia malayi | hypothetical protein | 0.0007 | 0.003 | 0.0034 |
Brugia malayi | Cathepsin L-like precursor | 0.0026 | 0.0626 | 0.1063 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0626 | 0.8502 |
Mycobacterium tuberculosis | Probable cytochrome P450 137 Cyp137 | 0.0031 | 0.0785 | 1 |
Echinococcus multilocularis | 0.0031 | 0.0785 | 0.0785 | |
Brugia malayi | Papain family cysteine protease containing protein | 0.0026 | 0.0626 | 0.1063 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0029 | 0.0736 | 0.1254 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0031 | 0.0785 | 0.0785 |
Brugia malayi | Cathepsin L-like precursor | 0.0026 | 0.0626 | 0.1063 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0009 | 0.0073 | 0.0108 |
Brugia malayi | cathepsin L-like precursor | 0.0017 | 0.0352 | 0.0592 |
Mycobacterium tuberculosis | Possible cytochrome P450 135B1 Cyp135B1 | 0.0031 | 0.0785 | 1 |
Onchocerca volvulus | 0.0026 | 0.0626 | 0.1341 | |
Loa Loa (eye worm) | fibroinase | 0.0026 | 0.0626 | 0.1063 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0037 | 0.0984 | 0.0984 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0037 | 0.0984 | 0.0984 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0098 | 0.2948 | 1 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0029 | 0.0736 | 1 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0029 | 0.0736 | 0.1254 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0058 | 0.1662 | 0.553 |
Echinococcus granulosus | cathepsin l1 | 0.0017 | 0.0352 | 0.0352 |
Echinococcus multilocularis | tumor protein p63 | 0.0273 | 0.8552 | 0.8552 |
Mycobacterium ulcerans | cytochrome P450 143A3 Cyp143A3 | 0.0031 | 0.0785 | 0.472 |
Onchocerca volvulus | Cathepsin L homolog | 0.0026 | 0.0626 | 0.1341 |
Mycobacterium ulcerans | cytochrome P450 187A4 Cyp187A4 | 0.0031 | 0.0785 | 0.472 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0098 | 0.2948 | 1 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0011 | 0.0148 | 0.2013 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0029 | 0.0736 | 1 |
Entamoeba histolytica | cysteine proteinase 2 | 0.0013 | 0.0225 | 0.1308 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0013 | 0.0225 | 0.0371 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0007 | 0.003 | 0.003 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0026 | 0.0626 | 0.1924 |
Leishmania major | lanosterol 14-alpha-demethylase, putative | 0.0031 | 0.0785 | 0.2273 |
Onchocerca volvulus | 0.0076 | 0.224 | 0.4972 | |
Echinococcus granulosus | cysteine protease | 0.0013 | 0.0225 | 0.0225 |
Plasmodium vivax | vivapain-2 | 0.0026 | 0.0626 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0013 | 0.0225 | 0.1308 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0148 | 0.0239 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0007 | 0.001 | 0.001 |
Brugia malayi | Domain found in Dishevelled, Egl-10, and Pleckstrin family protein | 0.0007 | 0.003 | 0.0034 |
Echinococcus multilocularis | cysteine protease | 0.0026 | 0.0626 | 0.0626 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.004 | 0.108 | 0.108 |
Mycobacterium tuberculosis | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) | 0.0031 | 0.0785 | 1 |
Mycobacterium tuberculosis | Cytochrome P450 121 Cyp121 | 0.0031 | 0.0785 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0026 | 0.0626 | 0.0626 |
Schistosoma mansoni | cpg binding protein | 0.0024 | 0.0556 | 0.0556 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0098 | 0.2948 | 1 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0029 | 0.0736 | 1 |
Echinococcus multilocularis | cpg binding protein | 0.0024 | 0.0556 | 0.0556 |
Leishmania major | cathepsin L-like protease | 0.0026 | 0.0626 | 0.1706 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0058 | 0.1662 | 0.2854 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0013 | 0.0225 | 0.0371 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0626 | 0.8502 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0098 | 0.2948 | 1 |
Trypanosoma cruzi | glycosyl hydrolase-like protein, putative | 0.0011 | 0.0148 | 0.0263 |
Schistosoma mansoni | alpha glucosidase | 0.0029 | 0.0736 | 0.0736 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0013 | 0.0225 | 0.0225 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.0007 | 0.003 | 0.003 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0007 | 0.001 | 0.001 |
Leishmania major | cathepsin L-like protease | 0.0026 | 0.0626 | 0.1706 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0626 | 0.1063 |
Leishmania major | cathepsin L-like protease | 0.0098 | 0.2948 | 1 |
Mycobacterium ulcerans | cytochrome P450 105Q4 Cyp105Q4 | 0.0031 | 0.0785 | 0.472 |
Echinococcus granulosus | cpg binding protein | 0.0024 | 0.0556 | 0.0556 |
Leishmania major | cytochrome p450-like protein | 0.0058 | 0.1662 | 0.5409 |
Schistosoma mansoni | smad1 5 8 and | 0.0007 | 0.001 | 0.001 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.004 | 0.1091 | 0.1867 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.004 | 0.1091 | 0.1867 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0029 | 0.0736 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 140 Cyp140 | 0.0031 | 0.0785 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0626 | 0.8502 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0029 | 0.0736 | 1 |
Mycobacterium ulcerans | cytochrome P450 140A5 Cyp140A5 | 0.0031 | 0.0785 | 0.472 |
Brugia malayi | Cathepsin L-like precursor | 0.0026 | 0.0626 | 0.1063 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0017 | 0.0352 | 0.3477 |
Entamoeba histolytica | cysteine protease, putative | 0.0013 | 0.0225 | 0.1308 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0007 | 0.0018 | 0.0014 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.0626 | 0.8502 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0132 | 0.402 | 0.402 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0626 | 0.8502 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.0626 | 0.8502 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.0007 | 0.003 | 0.003 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0007 | 0.001 | 0.001 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.108 | 0.1849 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0011 | 0.0148 | 0.2013 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0026 | 0.0626 | 0.0626 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0352 | 0.0592 |
Schistosoma mansoni | dep domain containing protein | 0.0007 | 0.003 | 0.003 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0013 | 0.0208 | 0.0342 |
Schistosoma mansoni | cpg binding protein | 0.0022 | 0.0516 | 0.0516 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0013 | 0.0225 | 0.3058 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0037 | 0.0984 | 0.0984 |
Loa Loa (eye worm) | cysteine protease | 0.0026 | 0.0626 | 0.1063 |
Mycobacterium tuberculosis | Probable cytochrome P450 144 Cyp144 | 0.0031 | 0.0785 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0021 | 0.0021 |
Mycobacterium tuberculosis | Probable cytochrome P450 124 Cyp124 | 0.0031 | 0.0785 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0013 | 0.0225 | 0.1308 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0007 | 0.001 | 0.001 |
Mycobacterium leprae | putative cytochrome p450 | 0.0031 | 0.0785 | 1 |
Plasmodium vivax | vivapain-1 | 0.0013 | 0.0225 | 0.2757 |
Loa Loa (eye worm) | histone methyltransferase | 0.0007 | 0.0021 | 0.0019 |
Leishmania major | cathepsin L-like protease | 0.0026 | 0.0626 | 0.1706 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0187 | 0.5799 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.4476 | 0.7714 |
Brugia malayi | Cathepsin L-like precursor | 0.0026 | 0.0626 | 0.1063 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0026 | 0.0626 | 0.0626 |
Echinococcus granulosus | GPCR family 2 | 0.0013 | 0.0208 | 0.0208 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0026 | 0.0626 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0009 | 0.0073 | 0.0108 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0026 | 0.0626 | 0.8502 |
Echinococcus granulosus | Pleckstrin G protein interacting region | 0.0007 | 0.003 | 0.003 |
Schistosoma mansoni | dishevelled | 0.0007 | 0.003 | 0.003 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0026 | 0.0626 | 0.8125 |
Echinococcus multilocularis | Pleckstrin G protein, interacting region | 0.0007 | 0.003 | 0.003 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0026 | 0.0626 | 0.0626 |
Onchocerca volvulus | 0.004 | 0.108 | 0.2364 | |
Mycobacterium tuberculosis | Probable cytochrome P450 132 Cyp132 | 0.0031 | 0.0785 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0029 | 0.0736 | 1 |
Plasmodium vivax | vivapain-3 | 0.0013 | 0.0225 | 0.2757 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0028 | 0.0682 | 0.1161 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0098 | 0.2948 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0013 | 0.0225 | 0.1308 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0007 | 0.001 | 0.001 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0026 | 0.0626 | 0.0626 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0007 | 0.003 | 0.003 |
Brugia malayi | cytochrome P450 | 0.0031 | 0.0785 | 0.1338 |
Mycobacterium tuberculosis | Probable cytochrome P450 125 Cyp125 | 0.0031 | 0.0785 | 1 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0013 | 0.0225 | 0.1308 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0013 | 0.0208 | 0.0342 |
Mycobacterium tuberculosis | Probable cytochrome P450 141 Cyp141 | 0.0031 | 0.0785 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.0031 | 0.0785 | 0.1338 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0029 | 0.0736 | 0.2099 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0352 | 0.0592 |
Brugia malayi | Cathepsin L-like precursor | 0.0026 | 0.0626 | 0.1063 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0098 | 0.2948 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.004 | 0.1091 | 0.1867 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0029 | 0.0736 | 0.2307 |
Entamoeba histolytica | cysteine protease, putative | 0.0013 | 0.0225 | 0.1308 |
Brugia malayi | Cytochrome P450 family protein | 0.0058 | 0.1662 | 0.2854 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.0626 | 0.8502 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0011 | 0.0148 | 0.2013 |
Schistosoma mansoni | regulator of G protein signaling | 0.0007 | 0.003 | 0.003 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.0208 | 0.0208 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0047 | 0.1319 | 0.1319 |
Echinococcus multilocularis | cathepsin L | 0.0013 | 0.0225 | 0.0225 |
Entamoeba histolytica | cysteine protease, putative | 0.0013 | 0.0225 | 0.1308 |
Leishmania major | cathepsin L-like protease | 0.0098 | 0.2948 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0026 | 0.0626 | 0.1063 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.0626 | 0.8502 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0029 | 0.0736 | 0.6269 |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.0031 | 0.0785 | 0.6701 |
Trypanosoma brucei | glucosidase, putative | 0.0029 | 0.0736 | 0.2099 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.0007 | 0.003 | 0.003 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0058 | 0.1662 | 0.2854 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0626 | 0.8502 |
Onchocerca volvulus | Cathepsin F homolog | 0.0026 | 0.0626 | 0.1341 |
Leishmania major | cathepsin L-like protease | 0.0026 | 0.0626 | 0.1706 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0208 | 0.0342 |
Onchocerca volvulus | 0.0026 | 0.0626 | 0.1341 | |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0037 | 0.0984 | 0.0984 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.1091 | 0.1867 |
Mycobacterium ulcerans | cytochrome P450 126A3 Cyp126A3 | 0.0031 | 0.0785 | 0.472 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0107 | 0.3215 | 0.5536 |
Loa Loa (eye worm) | ctsf protein | 0.0026 | 0.0626 | 0.1063 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0098 | 0.2948 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0026 | 0.0626 | 0.8125 |
Schistosoma mansoni | Smad4 | 0.0007 | 0.001 | 0.001 |
Schistosoma mansoni | cpg binding protein | 0.0024 | 0.0556 | 0.0556 |
Onchocerca volvulus | 0.0026 | 0.0626 | 0.1341 | |
Schistosoma mansoni | fyve finger-containing phosphoinositide kinase fyv1 | 0.0007 | 0.003 | 0.003 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0352 | 0.0592 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0029 | 0.0736 | 0.0736 |
Echinococcus granulosus | Smad4 | 0.0007 | 0.001 | 0.001 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0029 | 0.0736 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0013 | 0.0225 | 0.1308 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0626 | 0.8502 |
Mycobacterium tuberculosis | Probable cytochrome P450 monooxygenase 142 Cyp142 | 0.0031 | 0.0785 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0352 | 0.0592 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0029 | 0.0736 | 0.2307 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0058 | 0.1662 | 0.2854 |
Echinococcus multilocularis | GPCR, family 2 | 0.0013 | 0.0208 | 0.0208 |
Leishmania major | cathepsin L-like protease | 0.0026 | 0.0626 | 0.1706 |
Mycobacterium ulcerans | cytochrome P450 189A7 Cyp189A7 | 0.0031 | 0.0785 | 0.472 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0682 | 0.1161 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0011 | 0.0148 | 0.2013 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0626 | 0.8502 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0098 | 0.2948 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0013 | 0.0225 | 0.053 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0026 | 0.0626 | 0.0626 |
Trypanosoma cruzi | cysteine protease, putative | 0.0013 | 0.0225 | 0.053 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0013 | 0.0225 | 0.053 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0042 | 0.1156 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.0626 | 0.8502 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0031 | 0.0785 | 0.2477 |
Schistosoma mansoni | hypothetical protein | 0.0137 | 0.4189 | 0.4189 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0677 | 0.1152 |
Entamoeba histolytica | cysteine protease, putative | 0.0013 | 0.0225 | 0.1308 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0031 | 0.0785 | 1 |
Mycobacterium ulcerans | cytochrome P450 144A4 Cyp144A4 | 0.0031 | 0.0785 | 0.472 |
Mycobacterium tuberculosis | Probable cytochrome P450 130 Cyp130 | 0.0031 | 0.0785 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0013 | 0.0225 | 0.0275 |
Leishmania major | cytochrome p450-like protein | 0.0031 | 0.0785 | 0.2273 |
Loa Loa (eye worm) | G protein signaling regulator EGL-10 | 0.0007 | 0.003 | 0.0034 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0013 | 0.0208 | 0.0342 |
Trypanosoma brucei | Lanosterol 14-alpha demethylase | 0.0031 | 0.0785 | 0.2273 |
Schistosoma mansoni | alpha-glucosidase | 0.0113 | 0.3432 | 0.3432 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0626 | 0.8502 |
Entamoeba histolytica | cysteine protease, putative | 0.0013 | 0.0225 | 0.1308 |
Schistosoma mansoni | alpha-glucosidase | 0.0113 | 0.3432 | 0.3432 |
Schistosoma mansoni | z-protein (S1r protein) | 0.0007 | 0.003 | 0.003 |
Entamoeba histolytica | cysteine protease, putative | 0.0013 | 0.0225 | 0.1308 |
Onchocerca volvulus | 0.0017 | 0.0352 | 0.0726 | |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.003 | 0.0034 |
Entamoeba histolytica | cysteine protease, putative | 0.0013 | 0.0225 | 0.1308 |
Mycobacterium ulcerans | cytochrome P450 187A5 Cyp187A5 | 0.0031 | 0.0785 | 0.472 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0013 | 0.0208 | 0.0208 |
Mycobacterium ulcerans | cytochrome P450 142A3 Cyp142A3 | 0.0031 | 0.0785 | 0.472 |
Brugia malayi | hypothetical protein | 0.0007 | 0.003 | 0.0034 |
Loa Loa (eye worm) | cytochrome P450 | 0.0031 | 0.0785 | 0.1338 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0011 | 0.0148 | 0.2013 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0626 | 0.8502 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0077 | 0.2274 | 0.7656 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0013 | 0.0225 | 0.053 |
Mycobacterium tuberculosis | Probable cytochrome P450 123 Cyp123 | 0.0031 | 0.0785 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 143 Cyp143 | 0.0031 | 0.0785 | 1 |
Echinococcus multilocularis | smad | 0.0007 | 0.001 | 0.001 |
Brugia malayi | regulator of G-protein signaling egl-10 | 0.0007 | 0.003 | 0.0034 |
Entamoeba histolytica | cysteine protease, putative | 0.0013 | 0.0225 | 0.1308 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0037 | 0.0984 | 0.1683 |
Mycobacterium ulcerans | cytochrome P450 125A7 Cyp125A7 | 0.0031 | 0.0785 | 0.472 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0058 | 0.1662 | 0.553 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0026 | 0.0626 | 0.0626 |
Mycobacterium ulcerans | cytochrome P450 143A4 Cyp143A4 | 0.0031 | 0.0785 | 0.472 |
Echinococcus multilocularis | cysteine protease | 0.0026 | 0.0626 | 0.0626 |
Echinococcus granulosus | tumor protein p63 | 0.0273 | 0.8552 | 0.8552 |
Onchocerca volvulus | 0.0026 | 0.0626 | 0.1341 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0026 | 0.0626 | 0.8502 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0073 | 0.0108 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0626 | 0.8502 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0011 | 0.0148 | 0.2013 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0073 | 0.0108 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0098 | 0.2948 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0029 | 0.0736 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0013 | 0.0225 | 0.0275 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0011 | 0.0148 | 0.0239 |
Schistosoma mansoni | dishevelled | 0.0007 | 0.003 | 0.003 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0626 | 0.8502 |
Mycobacterium ulcerans | cytochrome P450 188A3 Cyp188A3 | 0.0031 | 0.0785 | 0.472 |
Brugia malayi | Domain found in Dishevelled, Egl-10, and Pleckstrin family protein | 0.0007 | 0.003 | 0.0034 |
Mycobacterium tuberculosis | Probable cytochrome P450 139 Cyp139 | 0.0031 | 0.0785 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0098 | 0.2948 | 1 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.0009 | 0.0073 | 0.0108 |
Loa Loa (eye worm) | DIX domain-containing protein | 0.0007 | 0.003 | 0.0034 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.003 | 0.0034 |
Onchocerca volvulus | Uncharacterized family 31 glucosidase KIAA1161 homolog | 0.0011 | 0.0148 | 0.0267 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0029 | 0.0736 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0626 | 0.8502 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0013 | 0.0208 | 0.0208 |
Schistosoma mansoni | cytochrome P450 | 0.0031 | 0.0785 | 0.0785 |
Mycobacterium ulcerans | cytochrome P450 51B1 Cyp51B1 | 0.0031 | 0.0785 | 0.472 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.0208 | 0.0208 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0026 | 0.0626 | 0.0626 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0029 | 0.0736 | 1 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0013 | 0.0225 | 0.0225 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0013 | 0.0225 | 0.0225 |
Echinococcus granulosus | geminin | 0.0137 | 0.4189 | 0.4189 |
Entamoeba histolytica | cysteine protease, putative | 0.0013 | 0.0225 | 0.1308 |
Mycobacterium ulcerans | cytochrome P450 123A3 Cyp123A3 | 0.0031 | 0.0785 | 0.472 |
Leishmania major | cytochrome p450-like protein | 0.0031 | 0.0785 | 0.2273 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0007 | 0.003 | 0.003 |
Onchocerca volvulus | 0.0026 | 0.0626 | 0.1341 | |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0029 | 0.0736 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.0107 | 0.3215 | 0.5536 |
Mycobacterium tuberculosis | Probable cytochrome P450 128 Cyp128 | 0.0031 | 0.0785 | 1 |
Onchocerca volvulus | 0.0022 | 0.0516 | 0.1093 | |
Mycobacterium ulcerans | cytochrome P450 150A6 Cyp150A6 | 0.0031 | 0.0785 | 0.472 |
Echinococcus granulosus | smad | 0.0007 | 0.001 | 0.001 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0026 | 0.0626 | 0.1063 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0626 | 0.8502 |
Schistosoma mansoni | hypothetical protein | 0.0137 | 0.4189 | 0.4189 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.0007 | 0.003 | 0.003 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.0208 | 0.0208 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.0146 | 0.4476 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.0626 | 0.8502 |
Leishmania major | cathepsin L-like protease | 0.0098 | 0.2948 | 1 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0029 | 0.0736 | 0.0736 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0098 | 0.2948 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0037 | 0.0984 | 0.0984 |
Leishmania major | cysteine peptidase A (CPA) | 0.0026 | 0.0626 | 0.1706 |
Schistosoma mansoni | hypothetical protein | 0.0028 | 0.0682 | 0.0682 |
Mycobacterium tuberculosis | Probable cytochrome P450 138 Cyp138 | 0.0031 | 0.0785 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0013 | 0.0225 | 0.1308 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0785 | 0.0785 |
Entamoeba histolytica | cysteine protease, putative | 0.0026 | 0.0626 | 0.8125 |
Brugia malayi | DIX domain containing protein | 0.0007 | 0.003 | 0.0034 |
Schistosoma mansoni | smad | 0.0007 | 0.001 | 0.001 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0022 | 0.0516 | 0.0873 |
Echinococcus multilocularis | Smad4 | 0.0007 | 0.001 | 0.001 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0009 | 0.0073 | 0.0108 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0013 | 0.0225 | 0.053 |
Brugia malayi | MH2 domain containing protein | 0.0097 | 0.2892 | 0.4978 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0098 | 0.2948 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0352 | 0.479 |
Entamoeba histolytica | cysteine protease, putative | 0.0013 | 0.0225 | 0.1308 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0132 | 0.402 | 0.6926 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0132 | 0.402 | 0.402 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0013 | 0.0208 | 0.0208 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0132 | 0.402 | 0.6926 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0037 | 0.0984 | 0.1683 |
Trypanosoma cruzi | cytochrome p450-like protein, putative | 0.0031 | 0.0785 | 0.2477 |
Mycobacterium ulcerans | cytochrome P450 124A1, Cyp124A1 | 0.0031 | 0.0785 | 0.472 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0352 | 0.0592 |
Brugia malayi | follicle stimulating hormone receptor | 0.0187 | 0.5799 | 1 |
Mycobacterium ulcerans | cytochrome P450 108B4 Cyp108B4 | 0.0031 | 0.0785 | 0.472 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0098 | 0.2948 | 1 |
Echinococcus multilocularis | geminin | 0.0137 | 0.4189 | 0.4189 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0097 | 0.2892 | 0.4978 |
Mycobacterium tuberculosis | Possible cytochrome P450 126 Cyp126 | 0.0031 | 0.0785 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.003 | 0.0034 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0058 | 0.1662 | 1 |
Brugia malayi | N-terminal motif family protein | 0.0146 | 0.4476 | 0.7714 |
Schistosoma mansoni | smad1 5 8 and | 0.0007 | 0.001 | 0.001 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0026 | 0.0626 | 1 |
Schistosoma mansoni | smad1 5 8 and | 0.0007 | 0.001 | 0.001 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0132 | 0.402 | 0.402 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0352 | 0.479 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0026 | 0.0626 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0026 | 0.0626 | 0.0626 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.009 | 0.2674 | 0.905 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0626 | 0.8502 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.0626 | 0.8502 |
Mycobacterium ulcerans | cytochrome P450 136A2 Cyp136A2 | 0.0031 | 0.0785 | 0.472 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.0626 | 0.8502 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0011 | 0.0148 | 0.2013 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0013 | 0.0208 | 0.0208 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0021 | 0.0021 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0011 | 0.0148 | 0.2013 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0007 | 0.003 | 0.003 |
Mycobacterium ulcerans | cytochrome p450 150 cyp150 | 0.0031 | 0.0785 | 0.472 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0037 | 0.0984 | 0.0984 |
Trypanosoma brucei | cytochrome P450, putative | 0.0058 | 0.1662 | 0.5409 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0017 | 0.0352 | 0.0592 |
Mycobacterium tuberculosis | Probable cytochrome P450 136 Cyp136 | 0.0031 | 0.0785 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0098 | 0.2948 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0097 | 0.2892 | 0.4978 |
Schistosoma mansoni | cathepsin s | 0.0009 | 0.0073 | 0.0073 |
Brugia malayi | CXXC zinc finger family protein | 0.0022 | 0.0516 | 0.0873 |
Echinococcus granulosus | cathepsin L | 0.0013 | 0.0225 | 0.0225 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0037 | 0.0984 | 0.0984 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0026 | 0.0626 | 0.1063 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0013 | 0.0225 | 0.1308 |
Trypanosoma cruzi | glycosyl hydrolase-like protein, putative | 0.0011 | 0.0148 | 0.0263 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI50 (functional) | = 1 uM | Growth inhibition of Homo sapiens (human) MDA-MB-231 cells after 72 hr by SRB assay | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.