Detailed information for compound 1836784

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 867.933 | Formula: C48H53NO14
  • H donors: 4 H acceptors: 9 LogP: 3.67 Rotable bonds: 15
    Rule of 5 violations (Lipinski): 2
  • SMILES: CC(=O)O[C@H]1C(=O)[C@]2(C)[C@@H](O)C[C@@H]3[C@]([C@H]2[C@@H]([C@]2(C(C1=C(C)[C@@H](OC(=O)[C@@H]([C@H](c1ccccc1)NC(=O)c1ccccc1)O)C2)(C)C)O)OC(=O)c1ccc(cc1)C)(CO3)OC(=O)C
  • InChi: 1S/C48H53NO14/c1-25-18-20-31(21-19-25)43(56)62-41-39-46(7,33(52)22-34-47(39,24-59-34)63-28(4)51)40(54)38(60-27(3)50)35-26(2)32(23-48(41,58)45(35,5)6)61-44(57)37(53)36(29-14-10-8-11-15-29)49-42(55)30-16-12-9-13-17-30/h8-21,32-34,36-39,41,52-53,58H,22-24H2,1-7H3,(H,49,55)/t32-,33-,34+,36-,37+,38+,39-,41-,46+,47-,48+/m0/s1
  • InChiKey: OBMWJELAFIKUEN-JBTWBBNCSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus granulosus calpain A 0.0017 0.0006 0.0006
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0159 0.0176 0.2778
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0039 0.0032 0.0363
Echinococcus multilocularis ryanodine receptor 44f 0.0541 0.0633 0.0633
Brugia malayi mbt repeat family protein 0.004 0.0033 0.0489
Brugia malayi Cytochrome P450 family protein 0.003 0.0021 0.0311
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0018 0.0007 0.0007
Treponema pallidum NADH oxidase 0.0039 0.0032 0.0363
Mycobacterium ulcerans acyl-CoA synthetase 0.002 0.0009 0.0075
Loa Loa (eye worm) calpain 0.0017 0.0006 0.0089
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0541 0.0633 1
Trichomonas vaginalis D-aminoacylase, putative 0.0193 0.0215 0.3402
Loa Loa (eye worm) hypothetical protein 0.0042 0.0035 0.055
Mycobacterium tuberculosis Conserved protein 0.0193 0.0215 0.0299
Entamoeba histolytica protein kinase, putative 0.0018 0.0006 0.0031
Mycobacterium ulcerans recombinase A 0.019 0.0213 0.2633
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0541 0.0633 0.0633
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0033 0.0024 0.0274
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0015 0.0003 0.0001
Loa Loa (eye worm) calpain family protein 1 0.0041 0.0034 0.0535
Loa Loa (eye worm) hypothetical protein 0.0541 0.0633 1
Brugia malayi ecdysteroid receptor 0.0018 0.0007 0.008
Echinococcus multilocularis expressed protein 0.0015 0.0003 0.0003
Brugia malayi beta-lactamase family protein 0.0193 0.0215 0.3386
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0541 0.0633 0.169
Onchocerca volvulus 0.0026 0.0016 0.0148
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0018 0.0007 0.0106
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0039 0.0032 0.0027
Schistosoma mansoni lamin 0.0026 0.0016 0.0038
Loa Loa (eye worm) hypothetical protein 0.0018 0.0007 0.0106
Echinococcus granulosus voltage gated hydrogen channel 1 0.0541 0.0633 0.0633
Leishmania major hypothetical protein, conserved 0.0541 0.0633 0.0628
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.002 0.0009 0.0083
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.002 0.0009 0.0011
Echinococcus multilocularis calpain A 0.0061 0.0058 0.0058
Schistosoma mansoni chromobox protein 0.0058 0.0054 0.014
Loa Loa (eye worm) hypothetical protein 0.0041 0.0034 0.0535
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.002 0.0009 0.0022
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0039 0.0032 0.0484
Onchocerca volvulus Serine\/threonine kinase homolog 0.0079 0.0079 0.1157
Echinococcus granulosus survival motor neuron protein 1 0.0214 0.0241 0.0241
Echinococcus granulosus lamin 0.0026 0.0016 0.0016
Loa Loa (eye worm) calpain 5 0.0017 0.0006 0.0089
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0003 0.0052
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.002 0.0009 0.0011
Echinococcus multilocularis calcium activated potassium channel 0.0542 0.0633 0.0633
Schistosoma mansoni RAR-like nuclear receptor 0.0018 0.0007 0.0012
Schistosoma mansoni voltage-gated potassium channel 0.0541 0.0633 0.169
Echinococcus multilocularis polycomb protein SCMH1 0.004 0.0033 0.0033
Schistosoma mansoni voltage-gated potassium channel 0.0541 0.0633 0.169
Echinococcus granulosus polycomb protein SCMH1 0.004 0.0033 0.0033
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0039 0.0032 0.0423
Echinococcus multilocularis thioredoxin glutathione reductase 0.0115 0.0122 0.0122
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0061 0.0058 0.015
Loa Loa (eye worm) TAR-binding protein 0.0114 0.0122 0.1927
Trypanosoma brucei PAB1-binding protein , putative 0.0023 0.0013 0.0117
Echinococcus multilocularis transient receptor potential cation channel 0.0541 0.0633 0.0633
Brugia malayi calpain 7 0.0017 0.0006 0.0063
Echinococcus granulosus transient receptor potential cation channel 0.0541 0.0633 0.0633
Brugia malayi cation channel family protein 0.0541 0.0633 1
Trypanosoma brucei recA bacterial DNA recombination protein, putative 0.0059 0.0055 0.0787
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0018 0.0007 0.008
Plasmodium vivax calpain, putative 0.0017 0.0006 0.0144
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.005 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0541 0.0633 1
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.002 0.0009 0.0083
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.002 0.0009 0.0011
Echinococcus granulosus TRP transient receptor potential channel 0.0541 0.0633 0.0633
Echinococcus multilocularis transient receptor potential cation channel 0.0541 0.0633 0.0633
Brugia malayi Steroid receptor seven-up type 2 0.0018 0.0007 0.008
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0193 0.0215 0.0299
Echinococcus multilocularis short transient receptor potential channel 6 0.0541 0.0633 0.0633
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0003 0.0052
Schistosoma mansoni tar DNA-binding protein 0.0114 0.0122 0.0321
Echinococcus granulosus calpain 7 C02 family 0.0017 0.0006 0.0006
Schistosoma mansoni transient receptor potential channel 0.0541 0.0633 0.169
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0541 0.0633 0.0633
Echinococcus multilocularis histone acetyltransferase MYST2 0.0045 0.0039 0.0039
Mycobacterium ulcerans hypothetical protein 0.0193 0.0215 0.2666
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.004 0.0033 0.0081
Mycobacterium leprae Conserved hypothetical protein 0.002 0.0009 0.0025
Trypanosoma cruzi hypothetical protein, conserved 0.0193 0.0215 0.3344
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0541 0.0633 0.0633
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0135
Toxoplasma gondii PHD-finger domain-containing protein 0.0024 0.0014 0.0077
Schistosoma mansoni voltage-gated potassium channel 0.0541 0.0633 0.169
Loa Loa (eye worm) hypothetical protein 0.0193 0.0215 0.3403
Echinococcus granulosus voltage gated potassium channel 0.0541 0.0633 0.0633
Echinococcus multilocularis hypothetical protein 0.0017 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0109 0.0115 0.1823
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0289 0.0331 0.1373
Schistosoma mansoni voltage-gated potassium channel 0.0541 0.0633 0.169
Echinococcus granulosus two pore calcium channel protein 2 0.0541 0.0633 0.0633
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0541 0.0633 0.169
Echinococcus granulosus transient receptor potential gamma protein 0.0541 0.0633 0.0633
Entamoeba histolytica hypothetical protein 0.01 0.0104 1
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0193 0.0215 0.3403
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0541 0.0633 0.169
Brugia malayi TAR-binding protein 0.0114 0.0122 0.1906
Schistosoma mansoni survival motor neuron protein 0.0044 0.0037 0.0094
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0018 0.0007 0.0007
Echinococcus granulosus SAM and MBT domain containing protein 0.004 0.0033 0.0033
Schistosoma mansoni voltage-gated potassium channel 0.0541 0.0633 0.169
Trypanosoma brucei polo-like protein kinase 0.0079 0.0079 0.1172
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0541 0.0633 0.0633
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0018 0.0007 0.0106
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0541 0.0633 1
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0541 0.0633 1
Echinococcus multilocularis transient receptor potential cation channel 0.0541 0.0633 0.0633
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0541 0.0633 1
Schistosoma mansoni retinoic acid receptor RXR 0.0018 0.0007 0.0012
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.002 0.0009 0.0011
Trichomonas vaginalis CAMK family protein kinase 0.0079 0.0079 0.125
Loa Loa (eye worm) cytochrome P450 family protein 0.003 0.0021 0.0336
Echinococcus granulosus microtubule associated protein 2 0.3132 0.3734 0.3734
Mycobacterium ulcerans hypothetical protein 0.002 0.0009 0.0075
Trichomonas vaginalis chromobox protein, putative 0.0035 0.0027 0.0423
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.002 0.0009 0.0011
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.002 0.0009 0.0083
Loa Loa (eye worm) jmjC domain-containing protein 0.0031 0.0022 0.0346
Schistosoma mansoni voltage-gated potassium channel 0.0541 0.0633 0.169
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0018 0.0007 0.008
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0061 0.0058 0.0058
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0541 0.0633 1
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0018 0.0007 0.008
Brugia malayi mbt repeat family protein 0.004 0.0033 0.0489
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0018 0.0007 0.0106
Trichomonas vaginalis penicillin-binding protein, putative 0.0193 0.0215 0.3402
Echinococcus granulosus beta LACTamase domain containing family member 0.0193 0.0215 0.0215
Trichomonas vaginalis CAMK family protein kinase 0.0079 0.0079 0.125
Loa Loa (eye worm) cytochrome P450 0.002 0.0009 0.0146
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.002 0.0009 0.0022
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0039 0.0032 0.0371
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0541 0.0633 0.0633
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0541 0.0633 0.0633
Loa Loa (eye worm) mbt repeat family protein 0.004 0.0033 0.0514
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0039 0.0032 0.0027
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0018 0.0007 0.008
Echinococcus multilocularis transfer RNA-Gly 0.0541 0.0633 0.0633
Giardia lamblia NADH oxidase lateral transfer candidate 0.0039 0.0032 0.2791
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0018 0.0007 0.0007
Brugia malayi AMP-binding enzyme family protein 0.002 0.0009 0.0109
Echinococcus granulosus sodium leak channel non selective protein 0.0541 0.0633 0.0633
Trichomonas vaginalis glutathione reductase, putative 0.0039 0.0032 0.0508
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.002 0.0009 0.0083
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0541 0.0633 0.169
Trypanosoma brucei trypanothione reductase 0.0114 0.0121 0.1845
Brugia malayi Latrophilin receptor protein 2 0.005 0.0045 0.0691
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0039 0.0032 0.1391
Loa Loa (eye worm) twinkle helicase 0.0195 0.0218 0.3444
Echinococcus granulosus calpain 0.0017 0.0006 0.0006
Echinococcus multilocularis GPCR, family 2 0.005 0.0045 0.0045
Entamoeba histolytica serine/threonine protein kinase, putative 0.0079 0.0079 0.7442
Schistosoma mansoni voltage-gated potassium channel 0.0541 0.0633 0.169
Schistosoma mansoni voltage-gated potassium channel 0.0541 0.0633 0.169
Echinococcus multilocularis survival motor neuron protein 1 0.0214 0.0241 0.0241
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0541 0.0633 0.0633
Schistosoma mansoni tar DNA-binding protein 0.0114 0.0122 0.0321
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0039 0.0032 0.0363
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0032 0.0498
Loa Loa (eye worm) voltage-dependent calcium channel 0.0541 0.0633 1
Echinococcus multilocularis lamin dm0 0.0026 0.0016 0.0016
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0039 0.0032 0.0423
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0029 0.002 0.0285
Schistosoma mansoni jumonji domain containing protein 0.0063 0.0061 0.0157
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0039 0.0032 0.0423
Echinococcus granulosus transient receptor potential cation channel 0.0541 0.0633 0.0633
Loa Loa (eye worm) hypothetical protein 0.0541 0.0633 1
Echinococcus granulosus calpain A 0.0061 0.0058 0.0058
Echinococcus multilocularis peregrin 0.0024 0.0014 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0024 0.0376
Schistosoma mansoni cpg binding protein 0.0027 0.0018 0.0042
Schistosoma mansoni serine/threonine protein kinase 0.0079 0.0079 0.0206
Mycobacterium tuberculosis Putative ferredoxin reductase 0.026 0.0296 0.0413
Echinococcus granulosus potassium voltage gated channel protein 0.0541 0.0633 0.0633
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.002 0.0009 0.0011
Entamoeba histolytica acyl-coA synthetase, putative 0.002 0.0009 0.0296
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.002 0.0009 0.0083
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0003 0.0052
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.002 0.0009 0.0083
Echinococcus multilocularis conserved hypothetical protein 0.0541 0.0633 0.0633
Brugia malayi calpain 5 0.0017 0.0006 0.0063
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0018 0.0007 0.0106
Plasmodium falciparum ataxin-2 like protein, putative 0.0023 0.0013 0.0873
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.0098 0.0256
Loa Loa (eye worm) hypothetical protein 0.0541 0.0633 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0007 0.0106
Brugia malayi latrophilin 2 splice variant baaae 0.0109 0.0115 0.1802
Brugia malayi PHD-finger family protein 0.0024 0.0014 0.0196
Brugia malayi ion channel NompC 0.0541 0.0633 1
Loa Loa (eye worm) cytochrome P450 family protein 0.003 0.0021 0.0336
Schistosoma mansoni jumonji/arid domain-containing protein 0.0031 0.0022 0.0053
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.002 0.0009 0.0075
Brugia malayi hypothetical protein 0.01 0.0104 0.1629
Onchocerca volvulus 0.0193 0.0215 0.3332
Loa Loa (eye worm) hypothetical protein 0.005 0.0045 0.0716
Loa Loa (eye worm) hypothetical protein 0.0541 0.0633 1
Schistosoma mansoni hypothetical protein 0.0799 0.0942 0.2518
Echinococcus multilocularis thyroid hormone receptor alpha 0.0018 0.0007 0.0007
Schistosoma mansoni hypothetical protein 0.0242 0.0274 0.0729
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0018 0.0007 0.0012
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0018 0.0007 0.0106
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0039 0.0032 0.0423
Brugia malayi Heterochromatin protein 1 0.0058 0.0054 0.0836
Plasmodium falciparum thioredoxin reductase 0.0114 0.0121 1
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0157 0.0172 0.0172
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.002 0.0009 0.001
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0018 0.0007 0.0012
Mycobacterium ulcerans lipase LipD 0.0193 0.0215 0.2666
Loa Loa (eye worm) hypothetical protein 0.0324 0.0372 0.5881
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0541 0.0633 0.169
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.002 0.0009 0.0011
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0541 0.0633 0.169
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0045 0.0039 0.0593
Echinococcus granulosus shaker cognate 0.0541 0.0633 0.0633
Loa Loa (eye worm) hypothetical protein 0.0324 0.0372 0.5881
Trichomonas vaginalis CAMK family protein kinase 0.0079 0.0079 0.125
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0094 0.0098 0.0098
Loa Loa (eye worm) thioredoxin reductase 0.0114 0.0121 0.1918
Trypanosoma cruzi PAB1-binding protein , putative 0.0023 0.0013 0.0117
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0041
Brugia malayi AMP-binding enzyme family protein 0.002 0.0009 0.0109
Echinococcus granulosus cpg binding protein 0.0027 0.0018 0.0018
Onchocerca volvulus 0.0193 0.0215 0.3332
Brugia malayi Nuclear hormone receptor-like 1 0.0018 0.0007 0.008
Schistosoma mansoni thyroid hormone receptor 0.0018 0.0007 0.0012
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0541 0.0633 0.0633
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.002 0.0009 0.0075
Loa Loa (eye worm) glutathione reductase 0.0114 0.0121 0.1918
Plasmodium falciparum ataxin-2 like protein, putative 0.0023 0.0013 0.0873
Schistosoma mansoni steroid hormone receptor ad4bp 0.0018 0.0007 0.0012
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0205
Echinococcus granulosus transient receptor potential cation channel 0.0541 0.0633 0.0633
Schistosoma mansoni apoferritin-2 0.0015 0.0003 0.0003
Echinococcus granulosus ferritin 0.0015 0.0003 0.0003
Onchocerca volvulus Huntingtin homolog 0.0324 0.0372 0.5837
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.002 0.0009 0.0083
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0541 0.0633 1
Loa Loa (eye worm) calcium channel 0.0541 0.0633 1
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0541 0.0633 0.169
Loa Loa (eye worm) hypothetical protein 0.0058 0.0055 0.0863
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.002 0.0009 0.0083
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0541 0.0633 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0018 0.0007 0.008
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0541 0.0633 1
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0541 0.0633 1
Echinococcus multilocularis cpg binding protein 0.0027 0.0018 0.0018
Brugia malayi CXXC zinc finger family protein 0.0026 0.0016 0.0227
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.0098 0.0256
Loa Loa (eye worm) MBCTL1 0.0045 0.0039 0.0618
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0541 0.0633 0.0633
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0541 0.0633 0.0633
Echinococcus granulosus intermediate filament protein 0.0026 0.0016 0.0016
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0094 0.0098 0.0098
Schistosoma mansoni voltage-gated potassium channel 0.0541 0.0633 0.169
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0541 0.0633 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0003 0.0052
Leishmania major lanosterol 14-alpha-demethylase, putative 0.002 0.0009 0.0004
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0541 0.0633 0.0633
Schistosoma mansoni voltage-gated potassium channel 0.0541 0.0633 0.169
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.002 0.0009 0.0083
Schistosoma mansoni hypothetical protein 0.0109 0.0115 0.0303
Echinococcus multilocularis beta LACTamase domain containing family member 0.0193 0.0215 0.0215
Onchocerca volvulus 0.004 0.0033 0.0412
Loa Loa (eye worm) ion channel NompC 0.0541 0.0633 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0007 0.0106
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0541 0.0633 1
Mycobacterium tuberculosis Conserved protein 0.0193 0.0215 0.0299
Schistosoma mansoni ferritin 0.0015 0.0003 0.0003
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0541 0.0633 0.169
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0039 0.0032 0.0043
Brugia malayi hypothetical protein 0.0023 0.0013 0.0179
Trichomonas vaginalis chromobox protein, putative 0.0035 0.0027 0.0423
Echinococcus granulosus transient receptor potential cation channel 0.0541 0.0633 0.0633
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0541 0.0633 0.0633
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.002 0.0009 0.0011
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0541 0.0633 0.0633
Schistosoma mansoni microtubule-associated protein tau 0.3132 0.3734 1
Brugia malayi olfactory channel protein osm-9 0.0541 0.0633 1
Brugia malayi Cytochrome P450 family protein 0.0064 0.0062 0.0951
Onchocerca volvulus 0.0026 0.0016 0.0151
Mycobacterium leprae RECA PROTEIN (RECOMBINASE A) [CONTAINS: Mle RECA INTEIN]. 0.019 0.0213 0.0878
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0094 0.0098 0.0098
Brugia malayi Transient-receptor-potential like protein 0.0541 0.0633 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0007 0.0106
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0018 0.0007 0.0012
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0018 0.0007 0.008
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.002 0.0009 0.0011
Leishmania major hypothetical protein, conserved 0.0193 0.0215 0.021
Brugia malayi photoreceptor-specific nuclear receptor 0.0018 0.0007 0.008
Echinococcus multilocularis PHD finger protein rhinoceros 0.0024 0.0014 0.0014
Mycobacterium ulcerans acyl-CoA synthetase 0.002 0.0009 0.0075
Trypanosoma cruzi hypothetical protein, conserved 0.0193 0.0215 0.3344
Echinococcus granulosus lamin dm0 0.0026 0.0016 0.0016
Trichomonas vaginalis penicillin-binding protein, putative 0.0193 0.0215 0.3402
Schistosoma mansoni cpg binding protein 0.0027 0.0018 0.0042
Plasmodium falciparum phd finger protein, putative 0.0024 0.0014 0.0961
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0193 0.0215 0.0299
Mycobacterium tuberculosis Probable esterase LipL 0.0193 0.0215 0.0299
Toxoplasma gondii transporter, cation channel family protein 0.0541 0.0633 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0135
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0094 0.0098 0.1523
Schistosoma mansoni voltage-gated ion channel 0.0541 0.0633 0.169
Loa Loa (eye worm) voltage-gated potassium channel 0.0541 0.0633 1
Loa Loa (eye worm) hypothetical protein 0.0541 0.0633 1
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0541 0.0633 0.169
Loa Loa (eye worm) hypothetical protein 0.0541 0.0633 1
Mycobacterium tuberculosis Probable reductase 0.026 0.0296 0.0413
Schistosoma mansoni calpain (C02 family) 0.0017 0.0006 0.0009
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.005 0.0045 0.0045
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0541 0.0633 0.0633
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0159 0.0176 0.2759
Echinococcus granulosus two pore calcium channel protein 1 0.0541 0.0633 0.0633
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0041
Trypanosoma cruzi trypanothione reductase, putative 0.0114 0.0121 0.1845
Echinococcus multilocularis hyperpolarization activated cyclic 0.0541 0.0633 0.0633
Echinococcus multilocularis transient receptor potential cation channel 0.0541 0.0633 0.0633
Echinococcus granulosus geminin 0.0799 0.0942 0.0942
Schistosoma mansoni hypothetical protein 0.01 0.0104 0.0274
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0029 0.002 0.0285
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.002 0.0009 0.0083
Schistosoma mansoni transient receptor potential channel 0.0541 0.0633 0.169
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0039 0.0032 0.2493
Echinococcus granulosus thioredoxin glutathione reductase 0.0115 0.0122 0.0122
Mycobacterium ulcerans bacterioferritin BfrA 0.0015 0.0003 0.0008
Echinococcus multilocularis jumonji domain containing protein 0.0034 0.0025 0.0025
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.005 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0214 0.0241 0.3803
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.002 0.0009 0.0083
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0094 0.0098 0.1545
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0015 0.0003 0.0002
Trichomonas vaginalis CAMK family protein kinase 0.0079 0.0079 0.125
Brugia malayi Bromodomain containing protein 0.0024 0.0014 0.0196
Schistosoma mansoni voltage-gated potassium channel 0.0541 0.0633 0.169
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0114 0.0122 0.1927
Leishmania major cytochrome p450-like protein 0.002 0.0009 0.0004
Echinococcus granulosus hyperpolarization activated cyclic 0.0541 0.0633 0.0633
Brugia malayi chromobox protein homolog 3 0.0033 0.0024 0.0352
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0039 0.0032 0.0423
Echinococcus multilocularis lysine specific demethylase 5A 0.0029 0.002 0.002
Schistosoma mansoni hypothetical protein 0.005 0.0045 0.0116
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0541 0.0633 1
Echinococcus granulosus GPCR family 2 0.005 0.0045 0.0045
Echinococcus multilocularis FTZ F1 alpha 0.0018 0.0007 0.0007
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0541 0.0633 1
Loa Loa (eye worm) hypothetical protein 0.0541 0.0633 1
Onchocerca volvulus Alhambra homolog 0.0024 0.0014 0.0116
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0079 0.0079 0.0074
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0032 0.0498
Echinococcus multilocularis calpain 7 (C02 family) 0.0017 0.0006 0.0006
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0289 0.0331 0.0461
Echinococcus granulosus calpain 5 0.0017 0.0006 0.0006
Treponema pallidum recombinase A 0.019 0.0213 0.2627
Echinococcus granulosus potassium voltage gated channel protein 0.0541 0.0633 0.0633
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0039 0.0032 0.0027
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0541 0.0633 0.0633
Onchocerca volvulus 0.0541 0.0633 1
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0018 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0026 0.0015 0.0244
Echinococcus granulosus chromobox protein 1 0.0058 0.0054 0.0054
Schistosoma mansoni tar DNA-binding protein 0.0114 0.0122 0.0321
Mycobacterium tuberculosis Probable lipase LipE 0.0193 0.0215 0.0299
Echinococcus multilocularis potassium large conductance calcium activated 0.0541 0.0633 0.0633
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0193 0.0215 0.0299
Schistosoma mansoni ferritin 0.0015 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0541 0.0633 1
Trichomonas vaginalis CAMK family protein kinase 0.0079 0.0079 0.125
Brugia malayi glutathione reductase 0.0114 0.0121 0.1896
Plasmodium falciparum glutathione reductase 0.0039 0.0032 0.2493
Toxoplasma gondii transporter, cation channel family protein 0.0541 0.0633 1
Onchocerca volvulus Huntingtin homolog 0.0324 0.0372 0.5837
Toxoplasma gondii thioredoxin reductase 0.0114 0.0121 0.1798
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.002 0.0009 0.0083
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0039 0.0032 0.2493
Echinococcus granulosus potassium voltage gated channel protein 0.0541 0.0633 0.0633
Schistosoma mansoni coup transcription factor 0.0018 0.0007 0.0012
Loa Loa (eye worm) hypothetical protein 0.0193 0.0215 0.3403
Leishmania major hypothetical protein, conserved 0.0023 0.0013 0.0007
Echinococcus multilocularis calpain 5 0.0017 0.0006 0.0006
Schistosoma mansoni voltage-gated potassium channel 0.0541 0.0633 0.169
Echinococcus multilocularis 0.002 0.0009 0.0009
Mycobacterium leprae Probable lipase LipE 0.0193 0.0215 0.0889
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0024 0.0014 0.0032
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.004 0.0033 0.0412
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0039 0.0032 0.0371
Entamoeba histolytica acyl-CoA synthetase, putative 0.002 0.0009 0.0296
Echinococcus granulosus transient receptor potential cation channel 0.0541 0.0633 0.0633
Schistosoma mansoni hypothetical protein 0.005 0.0045 0.0116
Schistosoma mansoni Replicative DNA helicase 0.0681 0.0801 0.2139
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0018 0.0007 0.0007
Echinococcus granulosus voltage dependent calcium channel 0.0541 0.0633 0.0633
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0016 0.0256
Brugia malayi cytochrome P450 0.002 0.0009 0.012
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0541 0.0633 0.0633
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0541 0.0633 0.0633
Trichomonas vaginalis mercuric reductase, putative 0.0039 0.0032 0.0508
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0193 0.0215 0.0571
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0541 0.0633 1
Mycobacterium tuberculosis Probable lipase LipD 0.0193 0.0215 0.0299
Toxoplasma gondii hypothetical protein 0.0541 0.0633 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0064 0.0062 0.0974
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0039 0.0032 0.0368
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0039 0.0032 0.1391
Schistosoma mansoni voltage-gated potassium channel 0.0541 0.0633 0.169
Entamoeba histolytica acyl-CoA synthetase, putative 0.002 0.0009 0.0296
Echinococcus granulosus voltage dependent calcium channel 0.0541 0.0633 0.0633
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0541 0.0633 1
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0061 0.0058 0.0058
Giardia lamblia Kinase, PLK 0.0079 0.0079 1
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0013 0.0197
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0541 0.0633 0.169
Schistosoma mansoni hypothetical protein 0.0044 0.0037 0.0094
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0289 0.0331 0.0461
Schistosoma mansoni hypothetical protein 0.002 0.0009 0.0019
Brugia malayi Thioredoxin reductase 0.0114 0.0121 0.1896
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0039 0.0032 0.0081
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0045 0.0039 0.0039
Schistosoma mansoni hypothetical protein 0.0541 0.0633 0.169
Schistosoma mansoni ferritin 0.0015 0.0003 0.0003
Leishmania major cytochrome p450-like protein 0.002 0.0009 0.0004
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0541 0.0633 0.169
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0541 0.0633 0.169
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.002 0.0009 0.0057
Trichomonas vaginalis esterase, putative 0.0193 0.0215 0.3402
Trichomonas vaginalis chromobox protein, putative 0.0058 0.0054 0.0859
Mycobacterium tuberculosis Probable replicative DNA helicase DnaB 0.5976 0.7138 1
Schistosoma mansoni vesicular amine transporter 0.0541 0.0633 0.169
Echinococcus multilocularis potassium voltage gated channel protein 0.0541 0.0633 0.0633
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0114 0.0121 0.0168
Schistosoma mansoni intermediate filament proteins 0.0026 0.0016 0.0038
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.026 0.0296 0.0413
Echinococcus granulosus tar DNA binding protein 0.0114 0.0122 0.0122
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.026 0.0296 0.1227
Schistosoma mansoni calpain-7 (C02 family) 0.0017 0.0006 0.0009
Toxoplasma gondii PHD-finger domain-containing protein 0.0024 0.0014 0.0077
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0193 0.0215 0.2666
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0018 0.0007 0.0106
Echinococcus multilocularis two pore calcium channel protein 2 0.0541 0.0633 0.0633
Schistosoma mansoni nuclear hormone receptor 0.0018 0.0007 0.0012
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0157 0.0172 0.0172
Mycobacterium tuberculosis Probable dehydrogenase 0.026 0.0296 0.0413
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0018 0.0007 0.008
Brugia malayi beta-lactamase 0.0193 0.0215 0.3386
Schistosoma mansoni voltage-gated cation channel 0.0541 0.0633 0.169
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0541 0.0633 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0018 0.0007 0.0106
Chlamydia trachomatis replicative DNA helicase 0.0681 0.0801 1
Loa Loa (eye worm) hypothetical protein 0.0541 0.0633 1
Echinococcus multilocularis transient receptor potential cation channel 0.0541 0.0633 0.0633
Echinococcus multilocularis calpain 0.0017 0.0006 0.0006
Mycobacterium ulcerans bacterioferritin BfrB 0.0015 0.0003 0.0008
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0541 0.0633 1
Mycobacterium leprae Conserved hypothetical protein 0.2009 0.239 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0041
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0039 0.0032 0.0423
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0039 0.0032 0.0032
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0541 0.0633 0.0633
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0541 0.0633 0.0633
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0018 0.0007 0.0007
Echinococcus multilocularis calpain family protein 1, d 0.0041 0.0034 0.0034
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0002 0.0026
Echinococcus multilocularis geminin 0.0799 0.0942 0.0942
Loa Loa (eye worm) voltage-gated potassium channel 0.0541 0.0633 1
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0018 0.0007 0.0007
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0541 0.0633 0.0633
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.002 0.0009 0.0011
Onchocerca volvulus 0.0041 0.0034 0.0433
Echinococcus multilocularis voltage dependent calcium channel 0.0541 0.0633 0.0633
Echinococcus multilocularis ecdysone induced protein 78C 0.0018 0.0007 0.0007
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0015 0.0003 0.0002
Leishmania major 4-coumarate:coa ligase-like protein 0.002 0.0009 0.0003
Schistosoma mansoni voltage-gated potassium channel 0.0541 0.0633 0.169
Schistosoma mansoni calpain C (C02 family) 0.0017 0.0006 0.0009
Loa Loa (eye worm) steroid hormone receptor 0.0018 0.0007 0.0106
Toxoplasma gondii histone lysine methyltransferase SET1 0.0049 0.0044 0.0554
Schistosoma mansoni 60S ribosomal protein L21 0.0541 0.0633 0.169
Schistosoma mansoni voltage-gated potassium channel 0.0541 0.0633 0.169
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0541 0.0633 1
Loa Loa (eye worm) hypothetical protein 0.0193 0.0215 0.3403
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0541 0.0633 0.0633
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0018 0.0007 0.0007
Schistosoma mansoni hypothetical protein 0.005 0.0045 0.0116
Loa Loa (eye worm) hypothetical protein 0.0541 0.0633 1
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0016 0.023
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.002 0.0009 0.0083
Echinococcus granulosus ryanodine receptor 44f 0.0541 0.0633 0.0633
Trichomonas vaginalis chromobox protein, putative 0.0058 0.0054 0.0859
Trypanosoma cruzi cytochrome p450-like protein, putative 0.002 0.0009 0.0057
Echinococcus multilocularis microtubule associated protein 2 0.3132 0.3734 0.3734
Echinococcus multilocularis hyperpolarization activated cyclic 0.0541 0.0633 0.0633
Schistosoma mansoni tar DNA-binding protein 0.0114 0.0122 0.0321
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0039 0.0032 0.0423
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0541 0.0633 0.0633
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0039 0.0032 0.0423
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0039 0.0032 0.0027
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0003 0.0052
Trypanosoma cruzi DNA repair protein, putative 0.0059 0.0055 0.0787
Trypanosoma brucei cytochrome P450, putative 0.003 0.0021 0.0249
Mycobacterium ulcerans beta-lactamase 0.0193 0.0215 0.2666
Echinococcus multilocularis two pore calcium channel protein 1 0.0541 0.0633 0.0633
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0055 0.0051 0.013
Loa Loa (eye worm) latrophilin receptor protein 2 0.005 0.0045 0.0716
Loa Loa (eye worm) hypothetical protein 0.0159 0.0176 0.2778
Schistosoma mansoni voltage-dependent calcium channel 0.0541 0.0633 0.169
Brugia malayi hypothetical protein 0.0324 0.0372 0.5871
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.002 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0041
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0541 0.0633 1
Brugia malayi nuclear receptor NHR-88 0.0018 0.0007 0.008
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0018 0.0007 0.0007
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0541 0.0633 0.169
Mycobacterium leprae conserved hypothetical protein 0.0193 0.0215 0.0889
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0541 0.0633 1
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0079 0.0079 0.0079
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0003 0.0052
Echinococcus granulosus transient receptor potential cation channel 0.0541 0.0633 0.0633
Trichomonas vaginalis D-aminoacylase, putative 0.0193 0.0215 0.3402
Schistosoma mansoni ryanodine receptor related 0.0541 0.0633 0.169
Onchocerca volvulus 0.0193 0.0215 0.3332
Trypanosoma cruzi PAB1-binding protein , putative 0.0023 0.0013 0.0117
Schistosoma mansoni myelin transcription factor 1 myt1 0.0045 0.0039 0.0099
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0377
Schistosoma mansoni ferritin light chain 0.0015 0.0003 0.0003
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.002 0.0009 0.0083
Echinococcus granulosus potassium large conductance calcium activated 0.0541 0.0633 0.0633
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.002 0.0009 0.0011
Schistosoma mansoni tar DNA-binding protein 0.0114 0.0122 0.0321
Brugia malayi jmjC domain containing protein 0.008 0.008 0.1244
Loa Loa (eye worm) RNA binding protein 0.0114 0.0122 0.1927
Echinococcus multilocularis chromobox protein 1 0.0058 0.0054 0.0054
Trichomonas vaginalis D-aminoacylase, putative 0.0193 0.0215 0.3402
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0039 0.0032 0.0423
Echinococcus granulosus voltage gated potassium channel 0.0541 0.0633 0.0633
Leishmania major trypanothione reductase 0.0114 0.0121 0.0116
Loa Loa (eye worm) hypothetical protein 0.0541 0.0633 1
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.002 0.0009 0.0083
Echinococcus multilocularis lamin 0.0026 0.0016 0.0016
Trichomonas vaginalis CAMK family protein kinase 0.0079 0.0079 0.125
Toxoplasma gondii transporter, cation channel family protein 0.0541 0.0633 1
Echinococcus multilocularis voltage gated potassium channel 0.0541 0.0633 0.0633
Leishmania major hypothetical protein, unknown function 0.0541 0.0633 0.0628
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.002 0.0009 0.0011
Loa Loa (eye worm) ryanodine receptor 0.0541 0.0633 1
Loa Loa (eye worm) hypothetical protein 0.0058 0.0055 0.0863
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0018 0.0007 0.008
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0039 0.0032 0.0423
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0541 0.0633 0.169
Loa Loa (eye worm) hypothetical protein 0.0193 0.0215 0.3403
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0039 0.0032 0.0032
Onchocerca volvulus 0.002 0.0009 0.003
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0541 0.0633 1
Plasmodium vivax hypothetical protein, conserved 0.0193 0.0215 1
Echinococcus multilocularis voltage gated potassium channel 0.0541 0.0633 0.0633
Echinococcus multilocularis potassium voltage gated channel protein 0.0541 0.0633 0.0633
Brugia malayi Cyclic-nucleotide gated cation channel 0.0541 0.0633 1
Schistosoma mansoni cytochrome P450 0.002 0.0009 0.0019
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.002 0.0009 0.0011
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0003 0.0052
Loa Loa (eye worm) hypothetical protein 0.0193 0.0215 0.3403
Loa Loa (eye worm) hypothetical protein 0.0045 0.0039 0.0618
Mycobacterium tuberculosis Possible penicillin-binding protein 0.123 0.1457 0.2039
Loa Loa (eye worm) hypothetical protein 0.0541 0.0633 1
Mycobacterium tuberculosis Probable hydrolase 0.0193 0.0215 0.0299
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0044 0.0037 0.0561
Schistosoma mansoni voltage-gated potassium channel 0.0541 0.0633 0.169
Echinococcus granulosus chromobox protein 1 0.0058 0.0054 0.0054
Trypanosoma cruzi polo-like protein kinase, putative 0.0079 0.0079 0.1172
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0039 0.0032 0.0371
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0541 0.0633 0.0633
Leishmania major 4-coumarate:coa ligase-like protein 0.002 0.0009 0.0003
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.002 0.0009 0.0011
Mycobacterium ulcerans replicative DNA helicase DnaB 0.0681 0.0801 1
Schistosoma mansoni voltage-gated potassium channel 0.0541 0.0633 0.169
Schistosoma mansoni kinase 0.004 0.0033 0.0082
Echinococcus granulosus PHD finger protein rhinoceros 0.0024 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0541 0.0633 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0033 0.0514
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0541 0.0633 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0041
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0541 0.0633 1
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0541 0.0633 0.169
Trypanosoma brucei hypothetical protein, conserved 0.0193 0.0215 0.3344
Schistosoma mansoni thyroid hormone receptor 0.0018 0.0007 0.0012
Brugia malayi RNA recognition motif domain containing protein 0.0114 0.0122 0.1906
Brugia malayi nuclear hormone receptor 0.0018 0.0007 0.008
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0135
Echinococcus granulosus hypothetical protein 0.0541 0.0633 0.0633
Loa Loa (eye worm) hypothetical protein 0.0541 0.0633 1
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0061 0.0058 0.015
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.002 0.0009 0.0083
Leishmania major cytochrome p450-like protein 0.003 0.0021 0.0016
Loa Loa (eye worm) hypothetical protein 0.0541 0.0633 1
Schistosoma mansoni cpg binding protein 0.0026 0.0016 0.0037
Echinococcus multilocularis voltage dependent calcium channel 0.0541 0.0633 0.0633
Brugia malayi RNA binding protein 0.0114 0.0122 0.1906
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0541 0.0633 0.169
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.002 0.0009 0.0011
Echinococcus multilocularis shaker cognate 0.0541 0.0633 0.0633
Schistosoma mansoni lamin 0.0026 0.0016 0.0038
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.01 0.0104 0.0104
Trypanosoma cruzi trypanothione reductase, putative 0.0039 0.0032 0.0423
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0018 0.0007 0.008
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0193 0.0215 0.0571
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0541 0.0633 0.0633
Echinococcus granulosus lysine specific demethylase 5A 0.0031 0.0022 0.0022
Brugia malayi cation channel family protein 0.0541 0.0633 1
Plasmodium falciparum glutathione reductase 0.0114 0.0121 1
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0035 0.0027 0.0321
Schistosoma mansoni sex comb on midleg homolog 0.004 0.0033 0.0081
Echinococcus multilocularis ferritin 0.0015 0.0003 0.0003
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.026 0.0296 0.0413
Trypanosoma cruzi polo-like protein kinase, putative 0.0079 0.0079 0.1172
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0541 0.0633 1
Loa Loa (eye worm) CXXC zinc finger family protein 0.0026 0.0016 0.0252
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.002 0.0009 0.0075
Loa Loa (eye worm) PHD-finger family protein 0.0024 0.0014 0.0221
Loa Loa (eye worm) hypothetical protein 0.0541 0.0633 1
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0024 0.0376
Brugia malayi hypothetical protein 0.0541 0.0633 1
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0018 0.0007 0.0012
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0541 0.0633 0.0633
Echinococcus multilocularis sodium leak channel non selective protein 0.0541 0.0633 0.0633
Echinococcus multilocularis tar DNA binding protein 0.0114 0.0122 0.0122
Echinococcus granulosus expressed protein 0.0015 0.0003 0.0003
Schistosoma mansoni ferritin 0.0015 0.0003 0.0003
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0039 0.0032 0.0423
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.002 0.0009 0.0057
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0039 0.0032 0.0423
Echinococcus multilocularis transient receptor potential cation channel 0.0541 0.0633 0.0633
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0541 0.0633 0.0633
Toxoplasma gondii LsmAD domain-containing protein 0.0023 0.0013 0.006
Loa Loa (eye worm) hypothetical protein 0.0541 0.0633 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0159 0.0176 0.2759
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0541 0.0633 0.169
Plasmodium falciparum thioredoxin reductase 0.0039 0.0032 0.2493
Entamoeba histolytica hypothetical protein 0.01 0.0104 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.0098 0.0256
Schistosoma mansoni transient receptor potential channel 0.0541 0.0633 0.169
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0018 0.0007 0.008
Onchocerca volvulus 0.0026 0.0015 0.014
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0079 0.0079 0.1251
Brugia malayi F/Y-rich N-terminus family protein 0.0016 0.0004 0.0036
Plasmodium vivax thioredoxin reductase, putative 0.0114 0.0121 0.5582
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0018 0.0007 0.0007
Chlamydia trachomatis recombinase RecA 0.019 0.0213 0.2633
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0018 0.0007 0.008
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0018 0.0007 0.0012
Entamoeba histolytica hypothetical protein 0.01 0.0104 1
Leishmania major 4-coumarate:coa ligase-like protein 0.002 0.0009 0.0003
Echinococcus granulosus short transient receptor potential channel 6 0.0541 0.0633 0.0633
Brugia malayi hypothetical protein 0.0214 0.0241 0.3787
Brugia malayi calpain family protein 1 0.0058 0.0055 0.0839
Mycobacterium ulcerans acyl-CoA synthetase 0.002 0.0009 0.0075
Mycobacterium ulcerans fatty-acid-CoA ligase 0.002 0.0009 0.0075
Plasmodium vivax glutathione reductase, putative 0.0114 0.0121 0.5582
Mycobacterium tuberculosis Probable oxidoreductase 0.0289 0.0331 0.0461
Trypanosoma cruzi cytochrome P450, putative 0.003 0.0021 0.0249
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0094 0.0098 0.0098
Onchocerca volvulus 0.0026 0.0016 0.0151
Brugia malayi steroid hormone receptor 0.0018 0.0007 0.008
Loa Loa (eye worm) hypothetical protein 0.0193 0.0215 0.3403
Brugia malayi intermediate filament protein 0.0026 0.0016 0.023
Mycobacterium tuberculosis Conserved protein 0.0193 0.0215 0.0299
Echinococcus granulosus ecdysone induced protein 78C 0.0018 0.0007 0.0007
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0541 0.0633 0.0633
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.002 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.0041 0.0034 0.0535
Echinococcus multilocularis potassium voltage gated channel protein 0.0541 0.0633 0.0633
Wolbachia endosymbiont of Brugia malayi replicative DNA helicase 0.0681 0.0801 1
Echinococcus granulosus calcium activated potassium channel 0.0542 0.0633 0.0633
Loa Loa (eye worm) hypothetical protein 0.0026 0.0016 0.0247
Echinococcus granulosus histone acetyltransferase MYST2 0.0045 0.0039 0.0039
Schistosoma mansoni transcription factor LCR-F1 0.01 0.0104 0.0274
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.002 0.0009 0.0083
Loa Loa (eye worm) jmjC domain-containing protein 0.005 0.0045 0.0711
Schistosoma mansoni two-pore calcium channel 0.0541 0.0633 0.169
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.002 0.0009 0.0011
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0039 0.0032 0.0371
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0541 0.0633 1
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.026 0.0296 0.0413
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.002 0.0009 0.0011
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0541 0.0633 0.0633
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0541 0.0633 0.0633
Brugia malayi calpain family protein 1 0.0058 0.0055 0.0839
Echinococcus granulosus peregrin 0.0024 0.0014 0.0014
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0018 0.0007 0.0007
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0541 0.0633 1
Mycobacterium leprae PROBABLE REPLICATIVE DNA HELICASE DNAB replicative DNA helicase 0.0681 0.0801 0.3341
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0009 0.001
Schistosoma mansoni ferritin light chain 0.0015 0.0003 0.0003
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0058 0.0055 0.0141
Echinococcus multilocularis musashi 0.0026 0.0016 0.0016
Schistosoma mansoni hypothetical protein 0.0799 0.0942 0.2518
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.008 0.008 0.008
Echinococcus granulosus short transient receptor potential channel 6 0.0541 0.0633 0.0633
Schistosoma mansoni hypothetical protein 0.0024 0.0014 0.0032
Trichomonas vaginalis ferritin, putative 0.0015 0.0003 0.005
Trichomonas vaginalis CAMK family protein kinase 0.0079 0.0079 0.125
Schistosoma mansoni calpain-7 (C02 family) 0.0017 0.0006 0.0009
Toxoplasma gondii ABC1 family protein 0.0193 0.0215 0.3305
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0045 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0018 0.0007 0.0106
Brugia malayi AMP-binding enzyme family protein 0.002 0.0009 0.0109
Brugia malayi beta-lactamase family protein 0.0193 0.0215 0.3386
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0541 0.0633 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0007 0.0106
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.002 0.0009 0.0011
Schistosoma mansoni sex comb on midleg homolog 0.004 0.0033 0.0081
Echinococcus multilocularis potassium voltage gated channel protein 0.0541 0.0633 0.0633
Echinococcus granulosus FTZ F1 alpha 0.0018 0.0007 0.0007
Echinococcus granulosus potassium voltage gated channel protein 0.0541 0.0633 0.0633
Loa Loa (eye worm) hypothetical protein 0.0018 0.0007 0.0106
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0541 0.0633 0.0633
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.002 0.0009 0.0083
Schistosoma mansoni hypothetical protein 0.005 0.0045 0.0116
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0193 0.0215 0.3386
Schistosoma mansoni transient receptor potential channel 4 0.0541 0.0633 0.169
Plasmodium vivax hypothetical protein, conserved 0.0024 0.0014 0.0537
Loa Loa (eye worm) hypothetical protein 0.0541 0.0633 1
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.002 0.0009 0.0057
Echinococcus granulosus potassium voltage gated channel protein 0.0541 0.0633 0.0633
Loa Loa (eye worm) hypothetical protein 0.0541 0.0633 1
Plasmodium vivax ataxin-2 like protein, putative 0.0023 0.0013 0.0487
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0541 0.0633 0.0633
Loa Loa (eye worm) voltage-gated calcium channel 0.0541 0.0633 1
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.002 0.0009 0.0083
Onchocerca volvulus 0.0044 0.0037 0.0485
Mycobacterium ulcerans esterase/lipase LipP 0.0193 0.0215 0.2666
Echinococcus granulosus jumonji domain containing protein 0.0034 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0541 0.0633 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.0031 0.0022 0.0053
Schistosoma mansoni voltage-gated potassium channel 0.0541 0.0633 0.169
Brugia malayi hypothetical protein 0.0015 0.0003 0.0021
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. 0.5485 0.655 0.9176
Toxoplasma gondii NADPH-glutathione reductase 0.0039 0.0032 0.0368
Echinococcus granulosus hyperpolarization activated cyclic 0.0541 0.0633 0.0633
Brugia malayi voltage-dependent calcium channel 0.0541 0.0633 1
Echinococcus granulosus cytochrome P450 2K1 0.002 0.0009 0.0009
Loa Loa (eye worm) calpain family protein 1 0.0058 0.0055 0.0863
Brugia malayi Cytochrome P450 family protein 0.003 0.0021 0.0311
Loa Loa (eye worm) CYP4Cod1 0.003 0.0021 0.0336
Echinococcus multilocularis SAM and MBT domain containing protein 0.004 0.0033 0.0033
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.008 0.008 0.008
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.005 0.0045 0.0691
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0018 0.0007 0.008
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.005 0.0045 0.0045
Treponema pallidum replicative DNA helicase (dnaB) 0.0681 0.0801 1
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0079 0.0079 0.0079
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0541 0.0633 0.0633
Entamoeba histolytica hypothetical protein 0.01 0.0104 1
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.002 0.0009 0.0083
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0541 0.0633 0.0633
Brugia malayi serine/threonine-protein kinase plk-2 0.0079 0.0079 0.1228
Loa Loa (eye worm) hypothetical protein 0.0541 0.0633 1
Mycobacterium leprae putative cytochrome p450 0.002 0.0009 0.0025
Loa Loa (eye worm) hypothetical protein 0.0024 0.0014 0.0221
Echinococcus multilocularis chromobox protein 1 0.0058 0.0054 0.0054
Brugia malayi Cytochrome P450 family protein 0.002 0.0009 0.012
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.003 0.0021 0.0234
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0018 0.0007 0.0012
Echinococcus multilocularis transient receptor potential gamma protein 0.0541 0.0633 0.0633
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0003 0.0052
Loa Loa (eye worm) heterochromatin protein 1 0.0058 0.0054 0.086
Wolbachia endosymbiont of Brugia malayi recombinase A 0.019 0.0213 0.2627
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0013 0.0197
Schistosoma mansoni Mername-AA248 (C02 family) 0.0017 0.0006 0.0009
Loa Loa (eye worm) hypothetical protein 0.0026 0.0016 0.0256
Brugia malayi jmjC domain containing protein 0.0031 0.0022 0.0321
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0018 0.0007 0.0007
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0016 0.0256
Trypanosoma cruzi DNA repair protein, putative 0.0059 0.0055 0.0787
Loa Loa (eye worm) hypothetical protein 0.0018 0.0007 0.0106
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.01 0.0104 0.0104
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0541 0.0633 1
Loa Loa (eye worm) beta-lactamase 0.0193 0.0215 0.3403
Schistosoma mansoni chromobox protein 0.0058 0.0054 0.014
Trypanosoma cruzi cytochrome P450, putative 0.003 0.0021 0.0249
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0018 0.0007 0.0007
Schistosoma mansoni calcium-activated potassium channel 0.0541 0.0633 0.169
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0018 0.0007 0.008
Toxoplasma gondii hypothetical protein 0.0541 0.0633 1
Schistosoma mansoni apoferritin-2 0.0015 0.0003 0.0003
Echinococcus multilocularis short transient receptor potential channel 6 0.0541 0.0633 0.0633

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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