Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | ubiquitin-activating enzyme E1b | 0.0033 | 0.0467 | 0.0976 |
Mycobacterium leprae | PROBABLE HOMOSERINE KINASE THRB | 0.0051 | 0.0958 | 0.2472 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0052 | 0.0036 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.008 | 0.1722 | 0.1692 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0291 | 0.0275 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0123 | 0.2834 | 0.6373 |
Toxoplasma gondii | GHMP kinase, N-terminal domain-containing protein | 0.0184 | 0.4447 | 1 |
Plasmodium vivax | SUMO-activating enzyme subunit 2, putative | 0.0033 | 0.0467 | 0.2481 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0052 | 0.0036 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0123 | 0.2834 | 0.6373 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0291 | 0.0653 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0123 | 0.2848 | 0.281 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.008 | 0.1722 | 0.1692 |
Trichomonas vaginalis | galactokinase, putative | 0.0051 | 0.0958 | 0.2126 |
Echinococcus granulosus | N acetylgalactosamine kinase | 0.0184 | 0.4447 | 0.4427 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0052 | 0.0036 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0845 | 0.1835 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0291 | 0.0275 |
Toxoplasma gondii | exonuclease III APE | 0.0019 | 0.0118 | 0.0149 |
Leishmania major | homoserine kinase, putative | 0.0121 | 0.279 | 0.2752 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0118 | 0.0186 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0111 | 0.2523 | 0.2484 |
Loa Loa (eye worm) | galactokinase | 0.0184 | 0.4447 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0582 | 0.0566 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0325 | 0.073 |
Echinococcus granulosus | sumo-activating enzyme subunit 2 | 0.0033 | 0.0467 | 0.0432 |
Schistosoma mansoni | diphosphomevalonate decarboxylase | 0.0051 | 0.0958 | 0.2091 |
Mycobacterium tuberculosis | Probable homoserine kinase ThrB | 0.0051 | 0.0958 | 0.0911 |
Trichomonas vaginalis | diphosphomevalonate decarboxylase, putative | 0.0051 | 0.0958 | 0.2126 |
Mycobacterium leprae | Probable 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase IspE (CMK) (4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase) | 0.0121 | 0.279 | 0.977 |
Loa Loa (eye worm) | ThiF family protein | 0.0033 | 0.0467 | 0.1049 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0582 | 0.0566 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0026 | 0.0291 | 0.0369 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0291 | 0.1427 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0053 | 0.0994 | 0.2616 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0019 | 0.0118 | 0.0367 |
Onchocerca volvulus | Huntingtin homolog | 0.0126 | 0.2919 | 0.7696 |
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.279 | 0.6275 |
Echinococcus multilocularis | N acetylgalactosamine kinase | 0.0184 | 0.4447 | 0.4427 |
Plasmodium falciparum | thioredoxin reductase | 0.0049 | 0.0887 | 0.4999 |
Brugia malayi | galactokinase family protein | 0.0184 | 0.4447 | 1 |
Toxoplasma gondii | ThiF family protein | 0.0033 | 0.0467 | 0.0942 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0026 | 0.0291 | 0.1427 |
Mycobacterium ulcerans | phosphomevalonate kinase | 0.0121 | 0.279 | 0.2752 |
Wolbachia endosymbiont of Brugia malayi | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 0.0121 | 0.279 | 1 |
Brugia malayi | diphosphomevalonate decarboxylase family protein | 0.0051 | 0.0958 | 0.2155 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0118 | 0.023 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0118 | 0.0186 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0017 | 0.0052 | 0.0037 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0123 | 0.2848 | 1 |
Toxoplasma gondii | thioredoxin reductase | 0.0049 | 0.0887 | 0.1899 |
Loa Loa (eye worm) | glutathione reductase | 0.0049 | 0.0887 | 0.1994 |
Plasmodium falciparum | glutathione reductase | 0.0049 | 0.0887 | 0.4999 |
Schistosoma mansoni | sumo-1-activating enzyme E1a | 0.0045 | 0.0792 | 0.1715 |
Brugia malayi | Thioredoxin reductase | 0.0049 | 0.0887 | 0.1994 |
Mycobacterium tuberculosis | Probable reductase | 0.0111 | 0.2523 | 0.2484 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.008 | 0.1722 | 0.3799 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0053 | 0.0994 | 0.0962 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0053 | 0.0994 | 0.0947 |
Brugia malayi | ThiF family protein | 0.0033 | 0.0467 | 0.1049 |
Echinococcus multilocularis | lamin dm0 | 0.0028 | 0.0338 | 0.0303 |
Brugia malayi | hypothetical protein | 0.0155 | 0.3691 | 0.83 |
Echinococcus multilocularis | SUMO activating enzyme subunit 2 | 0.0033 | 0.0467 | 0.0432 |
Brugia malayi | intermediate filament protein | 0.0028 | 0.0338 | 0.076 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0028 | 0.0338 | 0.0332 |
Schistosoma mansoni | mevalonate kinase | 0.0121 | 0.279 | 0.6245 |
Echinococcus multilocularis | lamin | 0.0028 | 0.0338 | 0.0303 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.053 | 0.1192 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.008 | 0.1722 | 0.3822 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0338 | 0.076 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.008 | 0.1722 | 0.3799 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0028 | 0.0338 | 0.1708 |
Plasmodium vivax | ubiquitin activating enzyme, putative | 0.0049 | 0.0912 | 0.5148 |
Treponema pallidum | galactokinase | 0.0344 | 0.8652 | 1 |
Trypanosoma cruzi | phosphomevalonate kinase protein, putative | 0.0051 | 0.0958 | 0.0944 |
Trichomonas vaginalis | mevalonate kinase, putative | 0.0051 | 0.0958 | 0.2126 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0111 | 0.2523 | 0.2484 |
Leishmania major | fucose kinase, putative | 0.0051 | 0.0958 | 0.0911 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0017 | 0.0052 | 0.0131 |
Loa Loa (eye worm) | intermediate filament protein | 0.0028 | 0.0338 | 0.076 |
Echinococcus granulosus | lamin dm0 | 0.0028 | 0.0338 | 0.0303 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0123 | 0.2848 | 0.281 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0017 | 0.0052 | 0.0036 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.1722 | 0.1942 |
Leishmania major | fucose kinase, putative | 0.0051 | 0.0958 | 0.0911 |
Treponema pallidum | hypothetical protein | 0.0121 | 0.279 | 0.3184 |
Echinococcus multilocularis | musashi | 0.0028 | 0.0338 | 0.0303 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0049 | 0.0887 | 0.0854 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0291 | 0.0653 |
Schistosoma mansoni | lamin | 0.0028 | 0.0338 | 0.0685 |
Toxoplasma gondii | hypothetical protein | 0.0049 | 0.0912 | 0.1956 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0582 | 0.0566 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0051 | 0.0956 | 0.215 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0017 | 0.0052 | 0.0082 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0118 | 0.0082 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.008 | 0.1722 | 1 |
Brugia malayi | Probable ClpP-like protease | 0.008 | 0.1722 | 0.3872 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.1722 | 0.3872 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0845 | 0.1835 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0049 | 0.0887 | 0.0872 |
Brugia malayi | ThiF family protein | 0.0049 | 0.0912 | 0.205 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0291 | 0.1427 |
Onchocerca volvulus | Huntingtin homolog | 0.0126 | 0.2919 | 0.7696 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0052 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0912 | 0.205 |
Mycobacterium ulcerans | diphosphomevalonate decarboxylase | 0.0051 | 0.0958 | 0.0911 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.053 | 0.1121 |
Brugia malayi | glutathione reductase | 0.0049 | 0.0887 | 0.1994 |
Brugia malayi | mevalonate kinase family protein | 0.0121 | 0.279 | 0.6275 |
Trypanosoma cruzi | ubiquitin-activating enzyme, putative | 0.0028 | 0.0347 | 0.0331 |
Echinococcus granulosus | Mevalonate galactokinase | 0.0121 | 0.279 | 0.2765 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.0036 | 0.0081 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0019 | 0.0118 | 0.0066 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.0845 | 0.0812 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0051 | 0.0956 | 0.215 |
Onchocerca volvulus | 0.0051 | 0.0958 | 0.1849 | |
Trypanosoma cruzi | mevalonate kinase, putative | 0.0121 | 0.279 | 0.2779 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0028 | 0.0338 | 0.076 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0052 | 0.0036 |
Plasmodium vivax | glutathione reductase, putative | 0.0049 | 0.0887 | 0.4999 |
Schistosoma mansoni | sumo-1-activating enzyme E1a | 0.0049 | 0.0912 | 0.1986 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0017 | 0.0052 | 0.0017 |
Brugia malayi | hypothetical protein | 0.0126 | 0.2919 | 0.6563 |
Giardia lamblia | Mevalonate kinase | 0.0121 | 0.279 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.0036 | 0.0081 |
Trypanosoma cruzi | galactokinase-like protein, putative | 0.0344 | 0.8652 | 0.8649 |
Trypanosoma brucei | trypanothione reductase | 0.0049 | 0.0887 | 0.1292 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0019 | 0.0118 | 0.0239 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0049 | 0.0887 | 0.4999 |
Loa Loa (eye worm) | hypothetical protein | 0.0126 | 0.2919 | 0.6563 |
Trichomonas vaginalis | galactokinase, putative | 0.0184 | 0.4447 | 1 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0111 | 0.2523 | 0.8705 |
Trypanosoma brucei | mevalonate-diphosphate decarboxylase | 0.0051 | 0.0958 | 0.1402 |
Trypanosoma cruzi | homoserine kinase | 0.0121 | 0.279 | 0.2779 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0019 | 0.0118 | 0.0066 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0037 | 0.0582 | 0.0548 |
Leishmania major | ubiquitin-activating enzyme-like protein | 0.0033 | 0.0467 | 0.0416 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0017 | 0.0052 | 0.0036 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0111 | 0.2523 | 0.2484 |
Trypanosoma cruzi | galactokinase, putative | 0.0344 | 0.8652 | 0.8649 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0019 | 0.0118 | 0.0102 |
Schistosoma mansoni | lamin | 0.0028 | 0.0338 | 0.0685 |
Loa Loa (eye worm) | hypothetical protein | 0.0155 | 0.3691 | 0.83 |
Leishmania major | mevalonate-diphosphate decarboxylase, putative | 0.0051 | 0.0958 | 0.0911 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0845 | 0.1835 |
Mycobacterium tuberculosis | Possible D-alpha-D-heptose-7-phosphate kinase HddA | 0.0121 | 0.279 | 0.2752 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0582 | 0.0566 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.1722 | 0.1678 |
Toxoplasma gondii | hypothetical protein | 0.0028 | 0.0338 | 0.0649 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0047 | 0.0845 | 0.1901 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0118 | 0.0392 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0036 | 0.0081 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0958 | 0.2155 |
Trypanosoma cruzi | fucose kinase, putative | 0.007 | 0.1442 | 0.1428 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.0036 | 0.0081 |
Onchocerca volvulus | 0.0155 | 0.3691 | 1 | |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.0118 | 0.0265 |
Trypanosoma cruzi | ubiquitin-activating enzyme, putative | 0.0033 | 0.0467 | 0.0451 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0123 | 0.2848 | 0.281 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0049 | 0.0111 |
Brugia malayi | MH2 domain containing protein | 0.0123 | 0.2834 | 0.6373 |
Plasmodium falciparum | SUMO-activating enzyme subunit 2 | 0.0033 | 0.0467 | 0.2481 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0118 | 0.0101 |
Trypanosoma brucei | phosphomevalonate kinase protein, putative | 0.0121 | 0.279 | 0.4239 |
Leishmania major | trypanothione reductase | 0.0049 | 0.0887 | 0.0839 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0118 | 0.0102 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0582 | 0.1237 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0017 | 0.0052 | 0.0082 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0118 | 0.0392 |
Trypanosoma brucei | mevalonate kinase, putative | 0.0121 | 0.279 | 0.4239 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0.0118 | 0.0076 |
Trichomonas vaginalis | galactokinase, putative | 0.0184 | 0.4447 | 1 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0049 | 0.0887 | 0.0839 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.053 | 0.1192 |
Loa Loa (eye worm) | hypothetical protein | 0.0126 | 0.2919 | 0.6563 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0049 | 0.0887 | 0.0854 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0053 | 0.0994 | 0.0947 |
Echinococcus multilocularis | diphosphomevalonate decarboxylase | 0.0051 | 0.0958 | 0.0926 |
Echinococcus granulosus | lamin | 0.0028 | 0.0338 | 0.0303 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.1722 | 1 |
Trichomonas vaginalis | galactokinase, putative | 0.0184 | 0.4447 | 1 |
Mycobacterium ulcerans | mevalonate kinase, Erg12 | 0.0121 | 0.279 | 0.2752 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0111 | 0.2523 | 0.2484 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.1722 | 1 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0118 | 0.0082 |
Chlamydia trachomatis | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 0.0051 | 0.0958 | 0.5425 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0017 | 0.0052 | 0.0118 |
Toxoplasma gondii | GHMP kinase, putative | 0.0121 | 0.279 | 0.623 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.1722 | 0.1678 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0051 | 0.0958 | 0.2126 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.1722 | 0.6098 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0053 | 0.0994 | 0.0962 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0017 | 0.0052 | 0.0036 |
Trypanosoma cruzi | homoserine kinase | 0.0121 | 0.279 | 0.2779 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.008 | 0.1722 | 0.5514 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0118 | 0.0265 |
Schistosoma mansoni | galactokinase | 0.0184 | 0.4447 | 1 |
Leishmania major | mevalonate kinase, putative | 0.0121 | 0.279 | 0.2752 |
Trypanosoma brucei | galactokinase-like protein, putative | 0.0262 | 0.6511 | 1 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0017 | 0.0052 | 0.0017 |
Echinococcus granulosus | diphosphomevalonate decarboxylase | 0.0051 | 0.0958 | 0.0926 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0019 | 0.0118 | 0.0102 |
Trypanosoma brucei | homoserine kinase | 0.0121 | 0.279 | 0.4239 |
Trypanosoma brucei | mevalonate diphosphate decarboxylase | 0.0051 | 0.0958 | 0.1402 |
Trichomonas vaginalis | galactokinase, putative | 0.0184 | 0.4447 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0037 | 0.0582 | 0.1237 |
Brugia malayi | hypothetical protein | 0.0037 | 0.0582 | 0.1308 |
Echinococcus granulosus | SUMO activating enzyme subunit 1 | 0.0049 | 0.0912 | 0.0879 |
Echinococcus multilocularis | Mevalonate galactokinase | 0.0121 | 0.279 | 0.2765 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.0845 | 0.0812 |
Leishmania major | hypothetical protein, conserved | 0.0026 | 0.0291 | 0.0239 |
Echinococcus granulosus | intermediate filament protein | 0.0028 | 0.0338 | 0.0303 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.0845 | 0.0812 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 0.0845 | 0.1901 |
Trypanosoma cruzi | fucose kinase, putative | 0.007 | 0.1442 | 0.1428 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0019 | 0.0118 | 0.0066 |
Trypanosoma cruzi | mevalonate-diphosphate decarboxylase, putative | 0.0051 | 0.0958 | 0.0944 |
Echinococcus multilocularis | SUMO activating enzyme subunit 1 | 0.0049 | 0.0912 | 0.0879 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0028 | 0.0338 | 0.076 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0118 | 0.023 |
Trypanosoma cruzi | phosphomevalonate kinase protein, putative | 0.0051 | 0.0958 | 0.0944 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.1722 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0051 | 0.0956 | 0.215 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0028 | 0.0338 | 0.1708 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0049 | 0.0887 | 0.1994 |
Trypanosoma brucei | ubiquitin-activating enzyme E1, putative | 0.0033 | 0.0467 | 0.0641 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0956 | 0.215 |
Mycobacterium ulcerans | homoserine kinase | 0.0121 | 0.279 | 0.2752 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0052 | 0.0036 |
Mycobacterium ulcerans | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 0.0121 | 0.279 | 0.2752 |
Plasmodium falciparum | SUMO-activating enzyme subunit 1 | 0.0049 | 0.0912 | 0.5148 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.0845 | 0.0812 |
Trichomonas vaginalis | galactokinase, putative | 0.007 | 0.1442 | 0.3218 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0026 | 0.0291 | 0.0542 |
Leishmania major | phosphomevalonate kinase protein, putative | 0.0121 | 0.279 | 0.2752 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0111 | 0.2523 | 0.2484 |
Schistosoma mansoni | intermediate filament proteins | 0.0028 | 0.0338 | 0.0685 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0037 | 0.0582 | 0.0548 |
Trypanosoma cruzi | mevalonate-diphosphate decarboxylase, putative | 0.0051 | 0.0958 | 0.0944 |
Giardia lamblia | Diphosphomevalonate decarboxylase | 0.0051 | 0.0958 | 0.3396 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.