Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | integrin beta subunit | 0.6165 | 0.5835 | 1 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.5156 | 0.4858 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.1591 | 0.1408 | 0.1408 |
Brugia malayi | hypothetical protein | 0.1591 | 0.1408 | 0.1377 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.5156 | 0.4858 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.5156 | 0.4858 | 1 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.5156 | 0.4858 | 0.4858 |
Echinococcus granulosus | integrin beta 2 | 0.7756 | 0.7374 | 1 |
Echinococcus granulosus | mitogen activated protein kinase | 0.5156 | 0.4858 | 0.6494 |
Loa Loa (eye worm) | hypothetical protein | 0.0337 | 0.0196 | 0.0196 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.5156 | 0.4858 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.5156 | 0.4858 | 1 |
Brugia malayi | EGF-like domain containing protein | 0.0337 | 0.0196 | 0.016 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.5156 | 0.4858 | 0.5 |
Trypanosoma brucei | protein kinase, putative | 0.5156 | 0.4858 | 0.5 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.5156 | 0.4858 | 0.5 |
Brugia malayi | MAP kinase sur-1 | 0.5156 | 0.4858 | 0.4839 |
Onchocerca volvulus | 0.0337 | 0.0196 | 0.5 | |
Trichomonas vaginalis | CMGC family protein kinase | 0.5156 | 0.4858 | 1 |
Brugia malayi | Kelch motif family protein | 0.1591 | 0.1408 | 0.1377 |
Brugia malayi | EGF-like domain containing protein | 0.0337 | 0.0196 | 0.016 |
Schistosoma mansoni | serine/threonine protein kinase | 0.5156 | 0.4858 | 0.8315 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.5156 | 0.4858 | 0.5 |
Echinococcus multilocularis | integrin beta 2 | 0.7756 | 0.7374 | 1 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.5156 | 0.4858 | 0.6494 |
Brugia malayi | EGF-like domain containing protein | 0.0337 | 0.0196 | 0.016 |
Loa Loa (eye worm) | integrin alpha pat-2 | 0.0266 | 0.0126 | 0.0126 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.5156 | 0.4858 | 0.5 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.5156 | 0.4858 | 0.6494 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.5156 | 0.4858 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0337 | 0.0196 | 0.0196 |
Trichomonas vaginalis | CMGC family protein kinase | 0.5156 | 0.4858 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0337 | 0.0196 | 0.0196 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.5156 | 0.4858 | 0.6494 |
Loa Loa (eye worm) | kelch domain-containing protein family protein | 0.1591 | 0.1408 | 0.1408 |
Giardia lamblia | Kinase, CMGC MAPK | 0.5156 | 0.4858 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0337 | 0.0196 | 0.0196 |
Brugia malayi | EGF-like domain containing protein | 0.0337 | 0.0196 | 0.016 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.