Detailed information for compound 32463

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 530.489 | Formula: C27H33Cl2N5O2
  • H donors: 0 H acceptors: 2 LogP: 5.35 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 2
  • SMILES: Clc1ccc(c(c1)Cl)[C@]1(CC[C@@H](O1)COc1ccc(cc1)N1CCN(CC1)C(C)C)Cn1cncn1
  • InChi: 1S/C27H33Cl2N5O2/c1-20(2)32-11-13-33(14-12-32)22-4-6-23(7-5-22)35-16-24-9-10-27(36-24,17-34-19-30-18-31-34)25-8-3-21(28)15-26(25)29/h3-8,15,18-20,24H,9-14,16-17H2,1-2H3/t24-,27+/m1/s1
  • InChiKey: LXQFDIAFKMEYAB-SQHAQQRYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0886 1 1
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 20 0.0115 0.0997 0.2833
Leishmania major diphthine synthase-like protein 0.0038 0.0102 0.0102
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0043 0.0164 0.0212
Echinococcus granulosus calcium transporting ATPase type 2C member 0.0036 0.0085 0.0241
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 0.005 0.0247 0.0702
Entamoeba histolytica calpain family cysteine protease, putative 0.0309 0.3263 1
Loa Loa (eye worm) peptidase C13 family protein 0.0038 0.01 0.0227
Echinococcus granulosus calpain A 0.0297 0.3123 0.887
Trichomonas vaginalis ubiquitin specific protease, putative 0.0071 0.0489 0.1074
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0357 0.3822 0.3822
Entamoeba histolytica cysteine protease, putative 0.0109 0.0929 0.2783
Leishmania major calcium-translocating P-type ATPase 0.0036 0.0085 0.0085
Brugia malayi cathepsin B-like cysteine proteinase 0.011 0.094 0.2461
Trypanosoma brucei hypothetical protein, conserved 0.0359 0.385 0.385
Loa Loa (eye worm) hypothetical protein 0.0132 0.1198 0.3363
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0247 0.0431
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.0234 0.0665
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0256 0.2643 0.6848
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0651 0.7259 0.7259
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0066 0.0424 0.1111
Trichomonas vaginalis ubiquitin specific protease, putative 0.005 0.0247 0.0431
Giardia lamblia Cathepsin B precursor 0.0043 0.0164 0.1746
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.005 0.0247 0.263
Entamoeba histolytica peptidase, C54 family 0.0049 0.0237 0.0646
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0578 0.6401 0.6401
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.005 0.0247 0.0677
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0205 0.205 0.5366
Leishmania major calpain protease-like protein 0.0269 0.2799 0.2799
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0086 0.0667 0.1545
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0253 0.2611 0.2611
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.005 0.0247 0.0647
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0047 0.0214 0.0214
Schistosoma mansoni Mername-AA248 (C02 family) 0.0297 0.3123 0.7602
Leishmania major small myristoylated protein-3, putative 0.039 0.4215 0.4215
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0038 0.01 0.004
Onchocerca volvulus 0.0205 0.205 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0437 0.4764 0.4764
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0357 0.3822 0.3822
Plasmodium falciparum diphthine methyl ester synthase, putative 0.0038 0.0102 0.0268
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0139 0.1284 0.3648
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0066 0.0424 0.0902
Echinococcus multilocularis cathepsin L 0.0043 0.0164 0.0466
Loa Loa (eye worm) hypothetical protein 0.005 0.0247 0.0647
Echinococcus multilocularis diphthine synthase 0.0038 0.0102 0.0291
Schistosoma mansoni ubiquitinyl hydrolase-UCH37 (C12 family) 0.0121 0.1073 0.2612
Trichomonas vaginalis Clan CA, family C12, ubiquitin hydrolase-like cysteine peptidase 0.0134 0.1224 0.3025
Mycobacterium leprae Probable dihydroorotate dehydrogenase PyrD 0.0356 0.382 0.5
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0073 0.0517 0.1149
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0038 0.01 0.004
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.005 0.0247 0.0677
Loa Loa (eye worm) hypothetical protein 0.0036 0.0085 0.0183
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0043 0.0164 0.021
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.011 0.094 0.094
Loa Loa (eye worm) hypothetical protein 0.0088 0.0689 0.1909
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0043 0.0164 0.043
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0164 0.021
Trypanosoma cruzi Cysteine peptidase, Clan CF, family C15 0.0462 0.5054 0.5054
Giardia lamblia Cathepsin L precursor 0.0043 0.0164 0.1746
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 24 0.005 0.0247 0.0702
Trichomonas vaginalis conserved hypothetical protein 0.0359 0.385 1
Entamoeba histolytica cysteine protease, putative 0.0109 0.0929 0.2783
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0205 0.205 0.5219
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.005 0.0247 0.0647
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0253 0.2611 0.2611
Onchocerca volvulus Huntingtin homolog 0.0132 0.1198 0.5665
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0109 0.0929 0.0929
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0281 0.2944 0.2944
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.039 0.4215 0.4215
Entamoeba histolytica hypothetical protein 0.0066 0.0432 0.125
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0669 0.7468 0.7468
Entamoeba histolytica cysteine proteinase, putative 0.0109 0.0929 0.2783
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.005 0.0247 0.0702
Schistosoma mansoni peptidase 0.005 0.0247 0.0602
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0038 0.01 0.004
Entamoeba histolytica calpain large subunit domain III containing protein 0.0062 0.0382 0.1093
Schistosoma mansoni ubiquitin-specific peptidase 24 (C19 family) 0.005 0.0247 0.0602
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.005 0.0247 0.0602
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0043 0.0164 0.0212
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 36 0.0072 0.0505 0.1436
Echinococcus multilocularis sarco:endoplasmic reticulum calcium ATPase 0.0036 0.0085 0.0241
Entamoeba histolytica cysteine protease, putative 0.0043 0.0164 0.042
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0055 0.0305 0.0867
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.011 0.094 0.2288
Trypanosoma brucei trypanothione synthetase, putative 0.0072 0.0505 0.0505
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0087 0.0674 0.0674
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Loa Loa (eye worm) hypothetical protein 0.005 0.0247 0.0647
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.039 0.4215 0.4215
Loa Loa (eye worm) hypothetical protein 0.005 0.0247 0.0647
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.039 0.4215 0.4215
Brugia malayi Cathepsin L-like precursor 0.0205 0.205 0.5366
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0088 0.0689 0.0689
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0134 0.1224 0.1224
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0047 0.0214 0.0342
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0043 0.0164 0.0399
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0234 0.057
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.005 0.0247 0.0435
Entamoeba histolytica cysteine proteinase 2 0.0109 0.0929 0.2783
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0886 1 1
Onchocerca volvulus 0.0205 0.205 1
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase isozyme L3, putative 0.0134 0.1224 0.3049
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0073 0.0517 0.1149
Trypanosoma cruzi hypothetical protein, conserved 0.0359 0.385 0.385
Loa Loa (eye worm) hypothetical protein 0.0139 0.1285 0.3613
Trypanosoma cruzi cysteine peptidase, Clan CA, family C54, putative 0.021 0.2113 0.2113
Leishmania major cysteine peptidase A (CPA) 0.0205 0.205 0.205
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Trypanosoma brucei inhibitor of cysteine peptidase 0.0251 0.2594 0.2594
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0291 0.3057 0.3057
Trypanosoma cruzi diphthine synthase, putative 0.0038 0.0102 0.0102
Plasmodium falciparum dihydroorotate dehydrogenase 0.0356 0.382 1
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.005 0.0247 0.0647
Trypanosoma cruzi cysteine peptidase, putative 0.0357 0.3822 0.3822
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0081 0.0609 0.0609
Brugia malayi Zinc finger, C2H2 type family protein 0.0139 0.1284 0.3362
Echinococcus granulosus diphthine synthase 0.0038 0.0102 0.0291
Schistosoma mansoni ubiquitin carboxyl-terminal hydrolase of the cysteine proteinase fold 0.005 0.0247 0.0602
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0115 0.0997 0.279
Plasmodium vivax vivapain-3 0.0109 0.0929 0.2259
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase, putative 0.005 0.0247 0.0677
Trypanosoma brucei cysteine peptidase, putative 0.0611 0.6789 0.6789
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0072 0.0505 0.1323
Giardia lamblia DUB-1 0.005 0.0247 0.263
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0235 0.2401 0.6152
Loa Loa (eye worm) calpain family protein 1 0.0235 0.2401 0.6801
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.005 0.0247 0.0647
Leishmania major META domain containing protein 0.0288 0.3022 0.3022
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0205 0.205 0.5219
Trypanosoma brucei dihydroorotate dehydrogenase (fumarate) 0.0356 0.382 0.382
Onchocerca volvulus 0.0205 0.205 1
Leishmania major ubiqitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0115 0.0997 0.0997
Giardia lamblia Cysteine protease 0.0043 0.0164 0.1746
Echinococcus multilocularis ubiquitin specific peptidase (c family) ubiquitin terminal hydrolase 0.0145 0.1348 0.3829
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0039 0.0111 0.0317
Plasmodium falciparum cysteine proteinase falcipain 1 0.0109 0.0929 0.2431
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0088 0.0689 0.0689
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase UCHL3 0.0134 0.1224 0.3049
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Echinococcus granulosus cysteine protease 0.0109 0.0929 0.2637
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0281 0.2938 0.2938
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.037 0.3977 0.3977
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0043 0.0164 0.042
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0455 0.1108
Echinococcus granulosus cathepsin l1 0.0139 0.1285 0.365
Trypanosoma brucei small myristoylated protein 1-2 0.0449 0.4897 0.4897
Trypanosoma brucei Calpain-like protein CALP1.3 0.0523 0.5763 0.5763
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0247 0.0431
Giardia lamblia Diphthine synthase 0.0038 0.0102 0.109
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0171 0.1653 0.1653
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0455 0.1108
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0701 0.7845 0.7845
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0247 0.0431
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0087 0.0674 0.1565
Brugia malayi hypothetical protein 0.005 0.0247 0.0647
Leishmania major ubiquitin carboxyl-terminal hydrolase, putative,cysteine peptidase, Clan CA, family C12, putative 0.0134 0.1224 0.1224
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 14 0.0079 0.0587 0.1536
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Trypanosoma cruzi Calcium ATPase SERCA-like 0.0036 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.0134 0.1224 0.3437
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.005 0.0247 0.0677
Toxoplasma gondii peptidase c13 family protein 0.0066 0.0425 0.0911
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0089 0.0701 0.1637
Trypanosoma cruzi kinesin, putative 0.0062 0.0382 0.0382
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.005 0.0247 0.0677
Plasmodium vivax unspecified product 0.0066 0.0424 0.0909
Leishmania major small myristoylated protein 4, putative 0.0669 0.7468 0.7468
Brugia malayi Membrane calcium atpase protein 3 0.004 0.0129 0.0338
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0043 0.0164 0.021
Plasmodium vivax diphthine synthase, putative 0.0038 0.0102 0.0047
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0139 0.1284 0.3185
Entamoeba histolytica peptidase, C54 family 0.0049 0.0237 0.0646
Schistosoma mansoni diphthine synthase 0.0038 0.0102 0.0249
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0145 0.1348 0.3355
Leishmania major small myristoylated protein-1 0.0449 0.4897 0.4897
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0047 0.0214 0.0574
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.0164 0.021
Giardia lamblia Cathepsin B precursor 0.011 0.094 1
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.005 0.0247 0.0431
Echinococcus multilocularis transfer RNA-Lys 0.0039 0.0112 0.0318
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0055 0.0305 0.0585
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.011 0.094 0.094
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0055 0.0305 0.0799
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Brugia malayi Dihydroorotate dehydrogenase, mitochondrial precursor, putative 0.0356 0.382 1
Schistosoma mansoni ubiquitinyl hydrolase-BAP1 (C12 family) 0.0066 0.0432 0.1052
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0065 0.0421 0.0421
Trypanosoma cruzi cysteine peptidase, putative 0.0357 0.3822 0.3822
Entamoeba histolytica peptidase, C54 family 0.0049 0.0237 0.0646
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.005 0.0247 0.0702
Loa Loa (eye worm) hypothetical protein 0.0092 0.0737 0.2045
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0516 0.5679 0.5679
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0455 0.1108
Toxoplasma gondii preprocathepsin c precursor, putative 0.0043 0.0164 0.0212
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0047 0.0214 0.0342
Giardia lamblia Cathepsin L precursor 0.0043 0.0164 0.1746
Echinococcus multilocularis cathepsin L cysteine protease 0.0205 0.205 0.5822
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase family 2 protein 0.0066 0.0424 0.0909
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0043 0.0164 0.0212
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.039 0.4215 0.4215
Schistosoma mansoni single-minded 0.0052 0.0271 0.0658
Loa Loa (eye worm) hypothetical protein 0.0066 0.0424 0.1153
Plasmodium vivax serine-repeat antigen (SERA) 0.0043 0.0164 0.0212
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Trypanosoma cruzi ubiquitin hydrolase, putative 0.023 0.2342 0.2342
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0145 0.1348 0.1348
Loa Loa (eye worm) hypothetical protein 0.0087 0.0674 0.1866
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0089 0.0701 0.1707
Brugia malayi hypothetical protein 0.0176 0.1709 0.4473
Plasmodium falciparum serine repeat antigen 1 0.0043 0.0164 0.043
Leishmania major hypothetical protein, unknown function 0.071 0.7945 0.7945
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0088 0.0689 0.1604
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0047 0.0214 0.0214
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0072 0.0505 0.1117
Loa Loa (eye worm) hypothetical protein 0.005 0.0247 0.0647
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0701 0.7845 0.7845
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0086 0.0666 0.1744
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Leishmania major trypanothione synthetase-like protein 0.0072 0.0505 0.0505
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0235 0.2401 0.6152
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0247 0.0431
Trypanosoma cruzi small myristoylated protein 1-2 0.0449 0.4897 0.4897
Toxoplasma gondii plasma membrane-type Ca(2+)-ATPase A1 PMCAA1 0.004 0.0129 0.0118
Brugia malayi cathepsin F-like cysteine proteinase 0.0043 0.0164 0.043
Schistosoma mansoni ubiquitin-specific peptidase 14 (C19 family) 0.0079 0.0586 0.1427
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0109 0.0937 0.2661
Schistosoma mansoni calpain-7 (C02 family) 0.0381 0.4108 1
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0043 0.0164 0.0212
Trichomonas vaginalis cation-transporting ATPase, putative 0.0047 0.0214 0.0342
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0171 0.1653 0.5025
Trypanosoma cruzi cysteine peptidase, putative 0.0109 0.0929 0.0929
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0065 0.0421 0.0421
Trypanosoma brucei unspecified product 0.0288 0.3022 0.3022
Brugia malayi calpain D 0.0309 0.3263 0.8541
Mycobacterium tuberculosis Probable dihydroorotate dehydrogenase PyrD 0.0356 0.382 0.5
Echinococcus multilocularis plasma membrane calcium transporting ATPase 0.004 0.0129 0.0366
Toxoplasma gondii ubiquitin thioesterase otubain-like family protein 0.0092 0.0737 0.1745
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Schistosoma mansoni Na+/K+ transporting ATPase subunit alpha 0.0036 0.0085 0.0207
Trypanosoma brucei pyroglutamyl-peptidase I, putative 0.0462 0.5054 0.5054
Trichomonas vaginalis calpain, putative 0.0235 0.2401 0.6152
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0139 0.1284 0.3883
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0109 0.0937 0.0937
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.005 0.0247 0.0602
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0034 0.0061 0.0061
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 12 0.0081 0.0609 0.1731
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Leishmania major receptor-type adenylate cyclase a-like protein 0.0288 0.3022 0.3022
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Entamoeba histolytica cysteine proteinase 1, putative 0.0109 0.0929 0.2783
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0072 0.0505 0.1323
Echinococcus granulosus Ubiquitin carboxyl terminal hydrolase 48 0.005 0.0247 0.0702
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0205 0.205 0.5797
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0043 0.0164 0.0409
Plasmodium falciparum non-SERCA-type Ca2+ -transporting P-ATPase 0.0036 0.0085 0.0222
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0139 0.1285 0.3188
Brugia malayi calpain 5 0.0062 0.0382 0.0999
Loa Loa (eye worm) hypothetical protein 0.0176 0.1709 0.4823
Echinococcus granulosus ubiquitin specific peptidase c family 0.0145 0.1348 0.3829
Leishmania major hypothetical protein, conserved,calpain-like cysteine peptidase, Clan CA, family C2 0.0604 0.6704 0.6704
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0205 0.205 0.5219
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0247 0.0431
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0049 0.0234 0.0613
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0109 0.0937 0.2617
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0499 0.5486 0.5486
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0087 0.0674 0.1997
Loa Loa (eye worm) hypothetical protein 0.005 0.0247 0.0647
Loa Loa (eye worm) hypothetical protein 0.0079 0.0586 0.1616
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.005 0.0247 0.0647
Leishmania major hypothetical protein, conserved 0.0288 0.3022 0.3022
Plasmodium vivax unspecified product 0.0043 0.0164 0.0212
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0247 0.0431
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0235 0.2401 0.6152
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0139 0.1284 0.3648
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Echinococcus granulosus cysteine protease atg4b 0.0088 0.0689 0.1957
Entamoeba histolytica hypothetical protein 0.0039 0.0111 0.0257
Loa Loa (eye worm) hypothetical protein 0.005 0.0247 0.0647
Onchocerca volvulus 0.0139 0.1285 0.6109
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Brugia malayi Cathepsin L-like precursor 0.0205 0.205 0.5366
Onchocerca volvulus 0.005 0.0247 0.0826
Trypanosoma brucei calpain-like protein, putative 0.0297 0.3123 0.3123
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0089 0.0701 0.0701
Echinococcus granulosus geminin 0.0182 0.1787 0.5076
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0043 0.0164 0.0212
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0079 0.0587 0.0587
Schistosoma mansoni family C12 unassigned peptidase (C12 family) 0.0134 0.1224 0.2979
Entamoeba histolytica cysteine protease, putative 0.0109 0.0929 0.2783
Loa Loa (eye worm) hypothetical protein 0.0064 0.0405 0.1097
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0047 0.0214 0.2275
Schistosoma mansoni family C13 non-peptidase homologue (C13 family) 0.0038 0.01 0.0244
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0043 0.0164 0.0212
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0886 1 1
Entamoeba histolytica cysteine proteinase, putative 0.0139 0.1285 0.3886
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0089 0.0701 0.1992
Entamoeba histolytica protein kinase, putative 0.0062 0.0382 0.1093
Onchocerca volvulus Cathepsin L homolog 0.0043 0.0164 0.0403
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0523 0.5763 0.5763
Plasmodium falciparum ubiquitin specific protease, putative 0.005 0.0247 0.0647
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0089 0.0701 0.0701
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0047 0.0214 0.0574
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0066 0.0424 0.1111
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0043 0.0164 0.0399
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0317 0.3365 0.3365
Entamoeba histolytica cysteine protease, putative 0.0109 0.0929 0.2783
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0288 0.3022 0.3022
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.011 0.094 0.2271
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0139 0.1284 0.3185
Trypanosoma cruzi cysteine peptidase, Clan CD, family C13, putative 0.0066 0.0425 0.0425
Brugia malayi GPI-anchor transamidase 0.0066 0.0425 0.1113
Echinococcus multilocularis calpain 7 (C02 family) 0.0331 0.3521 1
Trypanosoma brucei calpain-like protein, putative 0.0578 0.6401 0.6401
Loa Loa (eye worm) hypothetical protein 0.0235 0.2401 0.6801
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Echinococcus multilocularis set and mynd domain containing protein 0.0031 0.0022 0.0062
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0115 0.0997 0.0997
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0121 0.1073 0.1073
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0247 0.0431
Entamoeba histolytica hypothetical protein 0.0039 0.0111 0.0257
Trypanosoma cruzi cysteine peptidase, putative 0.0066 0.0424 0.0424
Entamoeba histolytica cysteine proteinase, putative 0.0109 0.0929 0.2783
Trypanosoma brucei diphthine synthase, putative 0.0038 0.0102 0.0102
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.0164 0.021
Leishmania major hypothetical protein, conserved 0.0072 0.0505 0.0505
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0643 0.716 0.716
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.005 0.0247 0.0431
Loa Loa (eye worm) calpain 0.0331 0.3521 1
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0247 0.0431
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0281 0.2938 0.2938
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0205 0.205 0.5219
Trypanosoma cruzi diphthine synthase, putative 0.0038 0.0102 0.0102
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Echinococcus granulosus cathepsin L cysteine proteinase 0.0205 0.205 0.5822
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0164 0.021
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0038 0.01 0.004
Trypanosoma cruzi cysteine peptidase, putative 0.0357 0.3822 0.3822
Leishmania major hypothetical protein, conserved 0.0359 0.385 0.385
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0205 0.205 0.5822
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 2, putative 0.005 0.0247 0.0435
Echinococcus granulosus ubiquitin specific peptidase 30 (C19 family) 0.005 0.0247 0.0702
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.005 0.0247 0.0431
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0247 0.0431
Loa Loa (eye worm) calpain D 0.0309 0.3263 0.9263
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0043 0.0164 0.042
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0431 0.4693 0.4693
Onchocerca volvulus Cathepsin F homolog 0.0205 0.205 1
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0178 0.1742 0.1742
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-4 0.0604 0.6704 0.6704
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0205 0.205 0.5219
Wolbachia endosymbiont of Brugia malayi dihydroorotate dehydrogenase 2 0.0356 0.382 0.5
Entamoeba histolytica cysteine protease, putative 0.0043 0.0164 0.042
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0297 0.3123 0.887
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0288 0.3022 0.3022
Trypanosoma cruzi hypothetical protein, conserved 0.0288 0.3022 0.3022
Echinococcus granulosus Ca2 transporting ATPase plasma membrane 0.004 0.0129 0.0366
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0055 0.0305 0.0743
Giardia lamblia Encystation-specific protease 0.0043 0.0164 0.1746
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.0234 0.0665
Loa Loa (eye worm) hypothetical protein 0.005 0.0247 0.0647
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0066 0.0424 0.1153
Leishmania major hypothetical protein, conserved 0.0288 0.3022 0.3022
Toxoplasma gondii cathepsin CPC1 0.0043 0.0164 0.0212
Brugia malayi Papain family cysteine protease containing protein 0.0043 0.0164 0.043
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 1, putative 0.005 0.0247 0.0435
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0043 0.0164 0.021
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.005 0.0247 0.0677
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.004 0.0129 0.0314
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.011 0.094 0.2288
Echinococcus multilocularis hypothetical protein 0.0297 0.3123 0.887
Trypanosoma brucei vacuolar-type Ca2+-ATPase 1 0.0047 0.0214 0.0214
Trypanosoma cruzi ubiquitin hydrolase, putative 0.023 0.2342 0.2342
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0205 0.205 0.5219
Plasmodium vivax GPI-anchor transamidase, putative 0.0066 0.0425 0.0911
Plasmodium falciparum serine repeat antigen 7 0.0043 0.0164 0.043
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.005 0.0247 0.0435
Echinococcus granulosus sarco:endoplasmic reticulum calcium ATPase 0.0036 0.0085 0.0241
Brugia malayi Peptidase family C54 containing protein 0.0088 0.0689 0.1803
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0109 0.0929 0.0929
Echinococcus granulosus cathepsin b 0.011 0.094 0.267
Loa Loa (eye worm) hypothetical protein 0.0132 0.1198 0.3363
Plasmodium vivax vivapain-1 0.0109 0.0929 0.2259
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0079 0.0587 0.0587
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0164 0.021
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0288 0.3022 0.3022
Entamoeba histolytica cysteine protease, putative 0.0109 0.0929 0.2783
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0043 0.0164 0.0212
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0088 0.0689 0.1604
Giardia lamblia Cathepsin B precursor 0.0043 0.0164 0.1746
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0055 0.0305 0.0813
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0253 0.2611 0.2611
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Leishmania major cathepsin L-like protease 0.0357 0.3822 0.3822
Echinococcus multilocularis cathepsin b 0.011 0.094 0.267
Trypanosoma cruzi cysteine peptidase, Clan CA, family C51, putative 0.0336 0.3577 0.3577
Loa Loa (eye worm) hypothetical protein 0.0038 0.0107 0.0247
Echinococcus multilocularis Tetracycline resistance leader peptide, TetL 0.0047 0.0214 0.0607
Loa Loa (eye worm) hypothetical protein 0.0066 0.0425 0.1155
Trypanosoma cruzi trypanothione synthetase 0.0072 0.0505 0.0505
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0087 0.0674 0.1565
Schistosoma mansoni ubiquitin-specific peptidase 30 (C19 family) 0.005 0.0247 0.0602
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.023 0.2342 0.2342
Brugia malayi Cathepsin L-like precursor 0.0139 0.1285 0.3365
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.005 0.0247 0.0702
Loa Loa (eye worm) hypothetical protein 0.0043 0.0164 0.0409
Trypanosoma cruzi cysteine protease, putative 0.0109 0.0929 0.0929
Brugia malayi Cathepsin L-like precursor 0.0139 0.1285 0.3365
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0086 0.0666 0.1844
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0253 0.2611 0.2611
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 5 0.0031 0.0021 0.0059
Leishmania major PFPI/DJ-1-like protein, putative 0.0485 0.5322 0.5322
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0038 0.01 0.004
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0043 0.0164 0.021
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 16 0.005 0.0247 0.0702
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0043 0.0164 0.043
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase isozyme 0.0134 0.1224 0.3476
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.005 0.0247 0.0702
Entamoeba histolytica cysteine protease, putative 0.0109 0.0929 0.2783
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0281 0.2938 0.2938
Leishmania major hypothetical protein, conserved 0.0288 0.3022 0.3022
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0205 0.205 0.5219
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0235 0.2401 0.6152
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.005 0.0247 0.0435
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Schistosoma mansoni hypothetical protein 0.0235 0.2401 0.5845
Leishmania major SUMO1/Ulp2, putative,cysteine peptidase, Clan CA, family C48, putative 0.0193 0.1917 0.1917
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.005 0.0247 0.0677
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Onchocerca volvulus 0.0205 0.205 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0031 0.0021 0.0021
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase, family 1 protein 0.0121 0.1073 0.2646
Entamoeba histolytica cysteine protease, putative 0.0043 0.0164 0.042
Trypanosoma cruzi cysteine peptidase, Clan CA, family C51, putative 0.0336 0.3577 0.3577
Brugia malayi cathepsin Z-like cysteine proteinase 0.0043 0.0164 0.043
Plasmodium falciparum serine repeat antigen 2 0.0043 0.0164 0.043
Loa Loa (eye worm) hypothetical protein 0.0079 0.0587 0.1617
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0086 0.0666 0.1744
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0109 0.0937 0.2661
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0043 0.0164 0.1746
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0357 0.3822 0.3822
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0205 0.205 0.5219
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0081 0.0609 0.1393
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.005 0.0247 0.0435
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0109 0.0929 0.0929
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase BAP1 0.0066 0.0432 0.1228
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Schistosoma mansoni ubiquitin specific protease 52 / poly(A) ribonuclease subunit pan2 0.0033 0.0044 0.0107
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0432 0.4699 0.4699
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0578 0.6401 0.6401
Trypanosoma cruzi cysteine peptidase inhibitor 0.0251 0.2594 0.2594
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0578 0.6401 0.6401
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Brugia malayi cathepsin L precursor 0.0043 0.0164 0.043
Brugia malayi Papain family cysteine protease containing protein 0.0043 0.0164 0.043
Brugia malayi Cathepsin L-like precursor 0.0205 0.205 0.5366
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0109 0.0937 0.2453
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0205 0.205 0.5797
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.084 0.9459 0.9459
Schistosoma mansoni autophagin-1 (C54 family) 0.0088 0.0689 0.1677
Brugia malayi TAR-binding protein 0.0068 0.0455 0.1191
Schistosoma mansoni ATPase 0.0036 0.0085 0.0207
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0297 0.3123 0.7602
Toxoplasma gondii autophagy-related cysteine peptidase atg4, putative 0.0049 0.0237 0.0408
Plasmodium vivax ubiquitin C-terminal hydrolase, family 1, putative 0.0121 0.1073 0.2646
Leishmania major hypothetical protein, conserved 0.0288 0.3022 0.3022
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0205 0.205 0.5219
Plasmodium falciparum serine repeat antigen 8 0.0043 0.0164 0.043
Brugia malayi calpain 7 0.0331 0.3521 0.9217
Giardia lamblia Cathepsin L precursor 0.0043 0.0164 0.1746
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0357 0.3822 0.3822
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.005 0.0247 0.0647
Schistosoma mansoni cathepsin B (C01 family) 0.0043 0.0164 0.0399
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0247 0.0431
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Plasmodium falciparum cysteine protease ATG4, putative 0.0049 0.0237 0.0621
Toxoplasma gondii cathepsin CPC2 0.0043 0.0164 0.0212
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase isozyme 0.0121 0.1073 0.3048
Brugia malayi cathepsin L-like cysteine proteinase 0.0043 0.0164 0.043
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.0234 0.0665
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0043 0.0164 0.0399
Trypanosoma cruzi otubain cysteine peptidase, Clan CA, family C65, putative 0.0092 0.0737 0.0737
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0043 0.0164 0.043
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0087 0.0674 0.0674
Brugia malayi hypoxia-induced factor 1 0.0162 0.155 0.4058
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0115 0.0997 0.2611
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0658 0.7339 0.7339
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0286 0.3002 0.3002
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 5 0.0031 0.0021 0.0059
Echinococcus granulosus GPI anchor transamidase 0.0066 0.0425 0.1208
Entamoeba histolytica peptidase, C54 family 0.0088 0.0689 0.2043
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0247 0.0431
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0253 0.2611 0.2611
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0302 0.3187 0.3187
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0455 0.1108
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0043 0.0164 0.0399
Schistosoma mansoni hypothetical protein 0.0182 0.1787 0.435
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 24 0.005 0.0247 0.0702
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0087 0.0674 0.1641
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0205 0.205 0.5219
Giardia lamblia Cysteine protease 0.0043 0.0164 0.1746
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0253 0.2611 0.2611
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0139 0.1284 0.3185
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0072 0.0505 0.0505
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0578 0.6401 0.6401
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0886 1 1
Entamoeba histolytica cysteine protease, putative 0.0109 0.0929 0.2783
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 46 0.0081 0.0609 0.1682
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.005 0.0247 0.0677
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0164 0.021
Leishmania major cathepsin L-like protease 0.0205 0.205 0.205
Loa Loa (eye worm) hypothetical protein 0.0062 0.0382 0.1031
Echinococcus granulosus Peptidase C54 0.0088 0.0689 0.1957
Toxoplasma gondii cathepsin CPL 0.0205 0.205 0.526
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 14 0.0079 0.0586 0.1666
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0043 0.0164 0.0212
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.0086 0.0666 0.1557
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0066 0.0425 0.0904
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 36 0.0072 0.0505 0.1436
Schistosoma mansoni ubiquitin-specific peptidase 10 (C19 family) 0.0145 0.1348 0.3281
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0499 0.5486 0.5486
Echinococcus granulosus single minded 2 0.0039 0.0112 0.0318
Trichomonas vaginalis calpain, putative 0.0235 0.2401 0.6152
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0072 0.0505 0.1117
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0205 0.205 0.5219
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0047 0.0214 0.0342
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.005 0.0247 0.0702
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0081 0.0609 0.0609
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0043 0.0164 0.021
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Schistosoma mansoni hypothetical protein 0.0039 0.0111 0.0271
Schistosoma mansoni cathepsin S (C01 family) 0.0043 0.0164 0.0399
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0043 0.0164 0.0212
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.005 0.0247 0.0431
Trypanosoma cruzi cysteine peptidase, Clan CA, family C51, putative 0.0336 0.3577 0.3577
Trypanosoma brucei cysteine peptidase C (CPC) 0.011 0.094 0.094
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0055 0.0305 0.0867
Entamoeba histolytica hypothetical protein 0.0043 0.0164 0.042
Leishmania major cathepsin L-like protease 0.0205 0.205 0.205
Plasmodium falciparum deubiquinating/deneddylating enzyme 0.0121 0.1073 0.281
Brugia malayi calpain 5 0.0235 0.2401 0.6286
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 14 0.0079 0.0586 0.1666
Toxoplasma gondii hypothetical protein 0.0235 0.2401 0.6201
Schistosoma mansoni ubiquitin-specific peptidase 4 (C19 family) 0.005 0.0247 0.0602
Schistosoma mansoni ubiquitin-specific peptidase 16 (C19 family) 0.005 0.0247 0.0602
Loa Loa (eye worm) hypothetical protein 0.0036 0.0085 0.0183
Trypanosoma cruzi cysteine peptidase, putative 0.0205 0.205 0.205
Trypanosoma cruzi trypanothione synthetase, putative 0.0072 0.0505 0.0505
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0043 0.0164 0.0399
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0072 0.0505 0.0505
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0523 0.5763 0.5763
Entamoeba histolytica cysteine proteinase, putative 0.0205 0.205 0.625
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0281 0.2938 0.2938
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0701 0.7845 0.7845
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0109 0.0937 0.0937
Giardia lamblia Cathepsin L precursor 0.0043 0.0164 0.1746
Trypanosoma brucei cysteine peptidase, Clan CA, family C51, putative 0.0336 0.3577 0.3577
Schistosoma mansoni ubiquitin-specific peptidase 42 (C19 family) 0.0072 0.0505 0.123
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0505 0.0505
Schistosoma mansoni cathepsin F (C01 family) 0.0139 0.1285 0.3129
Brugia malayi Cathepsin L-like precursor 0.0205 0.205 0.5366
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0047 0.0214 0.0574
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0038 0.01 0.004
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0066 0.0425 0.0904
Trypanosoma cruzi cysteine peptidase, Clan CA, family C48, putative 0.0193 0.1917 0.1917
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0066 0.0425 0.0904
Leishmania major dihydroorotate dehydrogenase 0.0356 0.382 0.382
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0039 0.0111 0.0317
Entamoeba histolytica calcium-transporting P-type ATPase, putative 0.0036 0.0085 0.0175
Giardia lamblia Hypothetical protein 0.0043 0.0164 0.1746
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 47 0.005 0.0247 0.0702
Trypanosoma cruzi cysteine proteinase, putative 0.0109 0.0929 0.0929
Trypanosoma brucei vacuolar-type Ca2+-ATPase 2 0.0047 0.0214 0.0214
Mycobacterium ulcerans putative regulatory protein 0.0039 0.0112 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0247 0.0431
Trichomonas vaginalis conserved hypothetical protein 0.0087 0.0674 0.1565
Trypanosoma cruzi glutathionylspermidine synthase, putative 0.0072 0.0505 0.0505
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Echinococcus multilocularis cysteine protease atg4b 0.0088 0.0689 0.1957
Leishmania major hypothetical protein, conserved 0.0288 0.3022 0.3022
Trypanosoma brucei AUT2/APG4/ATG4 cysteine peptidase, putative 0.0088 0.0689 0.0689
Loa Loa (eye worm) hypothetical protein 0.0139 0.1285 0.3613
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0079 0.0587 0.0587
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0247 0.0431
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0253 0.2611 0.2611
Leishmania major cathepsin L-like protease 0.0205 0.205 0.205
Trypanosoma brucei small myristoylated protein 1-1 0.0449 0.4897 0.4897
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.005 0.0247 0.0677
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0578 0.6401 0.6401
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.005 0.0247 0.0647
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.039 0.4215 0.4215
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0247 0.0431
Entamoeba histolytica peptidase, C54 family 0.021 0.2113 0.6444
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Onchocerca volvulus 0.0043 0.0164 0.0403
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0253 0.2611 0.2611
Schistosoma mansoni ubiquitin-specific peptidase 45 (C19 family) 0.005 0.0247 0.0602
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.037 0.3977 0.3977
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0205 0.205 0.5219
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0235 0.2401 0.6152
Leishmania major trypanothione synthetase, putative 0.0072 0.0505 0.0505
Leishmania major ubiquitin carboxyl-terminal hydrolase, putative,cysteine peptidase, Clan CA, family C12, putative 0.0121 0.1073 0.1073
Echinococcus multilocularis Ca2+ transporting ATPase plasma membrane 0.004 0.0129 0.0366
Onchocerca volvulus 0.0039 0.0112 0.0137
Echinococcus multilocularis cathepsin L cysteine protease 0.0205 0.205 0.5822
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0047 0.0214 0.0342
Onchocerca volvulus 0.0205 0.205 1
Entamoeba histolytica cysteine protease, putative 0.0043 0.0164 0.042
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0145 0.1348 0.3355
Leishmania major trypanothione synthetase, putative 0.0072 0.0505 0.0505
Schistosoma mansoni otubain-1 (C65 family) 0.0092 0.0737 0.1793
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.021 0.2113 0.2113
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0081 0.0609 0.0609
Brugia malayi Cathepsin L-like precursor 0.0066 0.0424 0.1111
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0139 0.1285 0.3188
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0432 0.4699 0.4699
Echinococcus multilocularis PAB dependent poly(A) specific ribonuclease 0.0033 0.0044 0.0125
Giardia lamblia Cathepsin B precursor 0.0043 0.0164 0.1746
Echinococcus granulosus set and mynd domain containing protein 0.0031 0.0022 0.0062
Echinococcus multilocularis cysteine protease 0.0205 0.205 0.5822
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0109 0.0937 0.2263
Schistosoma mansoni cathepsin F (C01 family) 0.0205 0.205 0.4989
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0047 0.0214 0.0214
Entamoeba histolytica hypothetical protein 0.0039 0.0111 0.0257
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0072 0.0505 0.0505
Trichomonas vaginalis ubiquitin specific protease, putative 0.005 0.0247 0.0431
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0302 0.3187 0.3187
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0437 0.4764 0.4764
Echinococcus granulosus calpain A 0.0297 0.3123 0.887
Giardia lamblia Hypothetical protein 0.0055 0.0305 0.3248
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Leishmania major small myristoylated protein-2 0.0763 0.8566 0.8566
Entamoeba histolytica hypothetical protein 0.005 0.0247 0.0677
Echinococcus granulosus cathepsin b 0.011 0.094 0.267
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0297 0.3123 0.7602
Brugia malayi bHLH-PAS transcription factor 0.0039 0.0112 0.0293
Echinococcus granulosus cathepsin L 0.0109 0.0929 0.2637
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0288 0.3022 0.3022
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0437 0.4764 0.4764
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0886 1 1
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.005 0.0247 0.0677
Trypanosoma brucei hypothetical protein 0.0516 0.5679 0.5679
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.071 0.7945 0.7945
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0055 0.0305 0.0857
Trypanosoma cruzi hypothetical protein, conserved 0.0288 0.3022 0.3022
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0115 0.0997 0.0997
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0357 0.3822 0.3822
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Echinococcus granulosus calpain 0.0297 0.3123 0.887
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0079 0.0586 0.1343
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0121 0.1073 0.1073
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0253 0.2611 0.2611
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Schistosoma mansoni dihydroorotate dehydrogenase 0.0356 0.382 0.9298
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase BAP1 0.0066 0.0432 0.1228
Leishmania major pyroglutamyl-peptidase I (C15 family) 0.0462 0.5054 0.5054
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0288 0.3022 0.3022
Entamoeba histolytica cysteine proteinase, putative 0.0205 0.205 0.625
Entamoeba histolytica cysteine protease, putative 0.0043 0.0164 0.042
Brugia malayi Na,K-ATPase alpha subunit 0.0036 0.0085 0.0222
Onchocerca volvulus 0.005 0.0247 0.0826
Entamoeba histolytica cysteine proteinase, putative 0.0109 0.0929 0.2783
Echinococcus multilocularis calpain 5 0.0297 0.3123 0.887
Echinococcus multilocularis calpain 0.0297 0.3123 0.887
Entamoeba histolytica cysteine protease, putative 0.0109 0.0929 0.2783
Leishmania major hypothetical protein, conserved 0.0288 0.3022 0.3022
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0643 0.716 0.716
Plasmodium vivax unspecified product 0.0109 0.0929 0.2259
Entamoeba histolytica cysteine protease, putative 0.0109 0.0929 0.2783
Schistosoma mansoni hemoglobinase (C13 family) 0.0038 0.01 0.0244
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0043 0.0164 0.021
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0043 0.0164 0.0399
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0611 0.6789 0.6789
Brugia malayi Papain family cysteine protease containing protein 0.0109 0.0929 0.2431
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0088 0.0689 0.1604
Echinococcus multilocularis tar DNA binding protein 0.0068 0.0455 0.1292
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.011 0.094 0.2288
Brugia malayi fibroinase precursor 0.0043 0.0164 0.043
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0047 0.0214 0.0342
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0437 0.4764 0.4764
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0139 0.1284 0.3648
Trypanosoma cruzi cysteine peptidase, Clan CA, family C51, putative 0.0336 0.3577 0.3577
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0455 0.1108
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0205 0.205 0.5219
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 23 0.0072 0.0505 0.1436
Trypanosoma cruzi trypanothione synthetase, putative 0.0072 0.0505 0.0505
Leishmania major cathepsin L-like protease 0.0357 0.3822 0.3822
Trypanosoma cruzi dihydroorotate dehydrogenase, putative 0.0356 0.382 0.382
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Trypanosoma cruzi SUMO1/Ulp2, putative 0.0193 0.1917 0.1917
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Onchocerca volvulus 0.005 0.0247 0.0826
Echinococcus granulosus calpain 7 C02 family 0.0331 0.3521 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0056 0.0317 0.0845
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0205 0.205 0.5219
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0205 0.205 0.5219
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0055 0.0305 0.0799
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0086 0.0667 0.1893
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0234 0.057
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.005 0.0247 0.0435
Plasmodium vivax serine-repeat antigen (SERA) 0.0043 0.0164 0.0212
Loa Loa (eye worm) ctsf protein 0.0205 0.205 0.5797
Trichomonas vaginalis calpain, putative 0.0235 0.2401 0.6152
Trypanosoma brucei Calpain-like protein 1.1 0.0886 1 1
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0281 0.2944 0.2944
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0087 0.0674 0.0674
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0235 0.2401 0.6152
Trichomonas vaginalis Clan CA, family C12, ubiquitin hydrolase-like cysteine peptidase 0.0134 0.1224 0.3025
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0055 0.0305 0.0743
Loa Loa (eye worm) ubiquitin C-terminal hydrolase UCH-L5 0.0121 0.1073 0.3007
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0089 0.0701 0.2081
Schistosoma mansoni hemoglobinase (C13 family) 0.0038 0.01 0.0244
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase, putative 0.0079 0.0587 0.1343
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0886 1 1
Echinococcus granulosus PAB dependent polyA specific ribonuclease 0.0033 0.0044 0.0125
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0086 0.0667 0.1545
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0164 0.021
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0431 0.4693 0.4693
Echinococcus multilocularis expressed protein 0.005 0.0247 0.0702
Trypanosoma cruzi dihydroorotate dehydrogenase, putative 0.0139 0.1284 0.1284
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0055 0.0305 0.0867
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0171 0.1653 0.1653
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0089 0.0701 0.0701
Plasmodium falciparum serine repeat antigen 6 0.0043 0.0164 0.043
Toxoplasma gondii hypothetical protein 0.005 0.0247 0.0435
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0087 0.0674 0.0674
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0205 0.205 0.5219
Entamoeba histolytica cysteine protease inhibitor 2 (EhICP2) 0.0251 0.2594 0.7933
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0043 0.0164 0.0409
Schistosoma mansoni family C12 unassigned peptidase (C12 family) 0.0134 0.1224 0.2979
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.005 0.0247 0.0677
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0281 0.2944 0.2944
Schistosoma mansoni ATPase 0.0036 0.0085 0.0207
Trypanosoma cruzi dihydroorotate dehydrogenase, putative 0.0356 0.382 0.382
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0066 0.0424 0.0902
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase family 2, putative 0.0089 0.0695 0.1633
Echinococcus granulosus plasma membrane calcium transporting ATPase 2 0.0047 0.0214 0.0607
Onchocerca volvulus Huntingtin homolog 0.0132 0.1198 0.5665
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0205 0.205 0.5219
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0047 0.0214 0.0214
Trypanosoma cruzi small myristoylated protein 1-1 0.0449 0.4897 0.4897
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.005 0.0247 0.0677
Plasmodium vivax ubiquitin specific protease, putative 0.005 0.0247 0.0435
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0087 0.0674 0.1914
Echinococcus multilocularis Peptidase C54 0.0088 0.0689 0.1957
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.084 0.9459 0.9459
Brugia malayi hypothetical protein 0.0132 0.1198 0.3136
Schistosoma mansoni ubiquitin-specific peptidase 22 (C19 family) 0.005 0.0247 0.0602
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0281 0.2944 0.2944
Echinococcus multilocularis ubiquitin specific peptidase 42 (C19 family) 0.0072 0.0505 0.1436
Trypanosoma cruzi hypothetical protein, conserved 0.0288 0.3022 0.3022
Schistosoma mansoni cathepsin F (C01 family) 0.0205 0.205 0.4989
Trypanosoma cruzi cruzipain precursor, putative 0.0066 0.0424 0.0424
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0043 0.0164 0.021
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0205 0.205 0.5219
Schistosoma mansoni ubiquitin-specific peptidase 46 (C19 family) 0.0081 0.0609 0.1483
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0253 0.2611 0.2611
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0247 0.0431
Trypanosoma brucei CHAP domain containing protein, putative 0.0072 0.0505 0.0505
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0087 0.0674 0.1914
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0357 0.3822 0.3822
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0253 0.2611 0.2611
Trypanosoma brucei cysteine peptidase, Clan CA, family C19, putative 0.0115 0.0997 0.0997
Plasmodium vivax vivapain-2 0.0205 0.205 0.526
Schistosoma mansoni aryl hydrocarbon receptor 0.0052 0.0271 0.0658
Schistosoma mansoni calpain-7 (C02 family) 0.0381 0.4108 1
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0247 0.0431
Brugia malayi hypothetical protein 0.0039 0.0111 0.0292
Plasmodium vivax dihydroorotate dehydrogenase, mitochondrial precursor, putative 0.0356 0.382 1
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.011 0.094 0.094
Entamoeba histolytica cysteine protease, putative 0.0205 0.205 0.625
Trypanosoma brucei otubain cysteine peptidase, Clan CA, family C65, putative 0.0092 0.0737 0.0737
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0432 0.4699 0.4699
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0297 0.3123 0.887
Trichomonas vaginalis conserved hypothetical protein 0.0235 0.2401 0.6152
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0247 0.0431
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0072 0.0505 0.1126
Echinococcus multilocularis calpain family protein 1, d 0.0235 0.2401 0.682
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase isozyme 0.0134 0.1224 0.3476
Brugia malayi RNA binding protein 0.0068 0.0455 0.1191
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0171 0.1653 0.1653
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 2, putative 0.005 0.0247 0.0647
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0205 0.205 0.5219
Echinococcus granulosus ubiquitin specific protease 41 0.0087 0.0674 0.1914
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0205 0.205 0.5366
Brugia malayi CG8232-PA 0.0064 0.0405 0.1059
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0043 0.0164 0.1746
Echinococcus granulosus plasma membrane calcium transporting ATPase 0.004 0.0129 0.0366
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 20 0.0115 0.0997 0.2833
Trypanosoma brucei Calpain-like protein 1.2 0.0677 0.7561 0.7561
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.0281 0.2938 0.2938
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.011 0.094 0.2288
Plasmodium vivax calpain, putative 0.0317 0.3365 0.8781
Plasmodium falciparum serine repeat antigen 5 0.0043 0.0164 0.043
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0055 0.0305 0.0585
Loa Loa (eye worm) hypothetical protein 0.005 0.0247 0.0647
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0072 0.0505 0.1475
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0055 0.0305 0.0585
Brugia malayi Papain family cysteine protease containing protein 0.0043 0.0164 0.043
Loa Loa (eye worm) hypothetical protein 0.0297 0.3123 0.8864
Schistosoma mansoni family C12 unassigned peptidase (C12 family) 0.0134 0.1224 0.2979
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0578 0.6401 0.6401
Schistosoma mansoni calpain (C02 family) 0.0297 0.3123 0.7602
Entamoeba histolytica cysteine protease, putative 0.0043 0.0164 0.042
Plasmodium falciparum GPI-anchor transamidase, putative 0.0066 0.0425 0.1113
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0109 0.0929 0.2241
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Schistosoma mansoni ubiquitinyl hydrolase-UCH37 (C12 family) 0.0121 0.1073 0.2612
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Giardia lamblia Cathepsin L precursor 0.0043 0.0164 0.1746
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0357 0.3822 0.3822
Trypanosoma brucei SUMO1/Ulp2, putative 0.0193 0.1917 0.1917
Giardia lamblia Cathepsin B precursor 0.0043 0.0164 0.1746
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0437 0.4764 0.4764
Echinococcus multilocularis Ubiquitin thioesterase otubain protein 0.0092 0.0737 0.2092
Loa Loa (eye worm) hypothetical protein 0.005 0.0247 0.0647
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0205 0.205 0.5219
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.005 0.0247 0.0647
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0247 0.0431
Leishmania major GPI-anchor transamidase subunit 8 (GPI8), putative 0.0066 0.0425 0.0425
Plasmodium falciparum calpain 0.0256 0.2643 0.6918
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0086 0.0666 0.7089
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.005 0.0247 0.0702
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0088 0.0689 0.1604
Entamoeba histolytica cysteine protease inhibitor 1 (EhICP1) 0.0251 0.2594 0.7933
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0578 0.6401 0.6401
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.005 0.0247 0.0435
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0043 0.0164 0.021
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0109 0.0929 0.226
Giardia lamblia Cysteine protease 0.0043 0.0164 0.1746
Onchocerca volvulus Cathepsin L homolog 0.0205 0.205 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0049 0.0234 0.0609
Schistosoma mansoni hypothetical protein 0.005 0.0247 0.0602
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0087 0.0674 0.1914
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Trypanosoma cruzi dihydroorotate dehydrogenase (fumarate), putative 0.0356 0.382 0.382
Entamoeba histolytica cysteine protease, putative 0.0109 0.0929 0.2783
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0043 0.0164 0.1746
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0038 0.01 0.004
Echinococcus granulosus cathepsin L cysteine protease 0.0109 0.0929 0.2637
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0677 0.7561 0.7561
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0088 0.0689 0.1677
Loa Loa (eye worm) hypothetical protein 0.0139 0.1285 0.3613
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0109 0.0929 0.226
Entamoeba histolytica cysteine proteinase, putative 0.0109 0.0929 0.2783
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0043 0.0164 0.043
Onchocerca volvulus 0.0205 0.205 1
Trypanosoma brucei amidase, putative 0.0072 0.0505 0.0505
Schistosoma mansoni glycosylphosphatidylinositol:protein transamidase (C13 family) 0.0066 0.0425 0.1035
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.005 0.0247 0.0677
Loa Loa (eye worm) TAR-binding protein 0.0068 0.0455 0.1241
Trypanosoma brucei calpain-like protein, putative 0.0317 0.3365 0.3365
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Trypanosoma cruzi otubain cysteine peptidase, Clan CA, family C65, putative 0.0092 0.0737 0.0737
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0086 0.0667 0.1893
Trypanosoma brucei antigen, putative 0.0297 0.3123 0.3123
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0171 0.1653 0.1653
Schistosoma mansoni cathepsin s 0.0066 0.0424 0.1033
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0089 0.0701 0.165
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 5 0.0084 0.0643 0.1827
Leishmania major kinesin, putative 0.0062 0.0382 0.0382
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0516 0.5679 0.5679
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0055 0.0305 0.0813
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0145 0.1348 0.1348
Loa Loa (eye worm) hypothetical protein 0.0235 0.2401 0.6801
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0043 0.0164 0.0409
Plasmodium falciparum ubiquitin specific protease, putative 0.005 0.0247 0.0647
Loa Loa (eye worm) hypothetical protein 0.0066 0.0424 0.1153
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0043 0.0164 0.021
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.084 0.9459 0.9459
Trypanosoma cruzi conserved protein 0.0466 0.5098 0.5098
Brugia malayi ubiquitin C-terminal hydrolase UCH-L5 0.0121 0.1073 0.281
Loa Loa (eye worm) hypothetical protein 0.0043 0.0164 0.0409
Mycobacterium ulcerans hypothetical protein 0.0106 0.0902 0.2187
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0079 0.0586 0.1535
Trypanosoma brucei glutathionylspermidine synthetase, putative 0.0072 0.0505 0.0505
Echinococcus granulosus cathepsin l cysteine peptidase 0.0205 0.205 0.5822
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0055 0.0305 0.0799
Loa Loa (eye worm) hypothetical protein 0.005 0.0247 0.0647
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0109 0.0937 0.0937
Loa Loa (eye worm) hypothetical protein 0.0066 0.0424 0.1153
Onchocerca volvulus Legumain homolog 0.0038 0.01 0.0077
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0611 0.6789 0.6789
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0139 0.1284 0.3648
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0043 0.0164 0.0399
Brugia malayi diphthine synthase 0.0038 0.0102 0.0268
Trypanosoma cruzi trypanothione synthetase-like protein, putative 0.0072 0.0505 0.0505
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0247 0.0431
Brugia malayi RNA recognition motif domain containing protein 0.0068 0.0455 0.1191
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0055 0.0305 0.0585
Echinococcus multilocularis calpain A 0.0297 0.3123 0.887
Brugia malayi Papain family cysteine protease containing protein 0.0109 0.0929 0.2431
Plasmodium vivax U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0055 0.0305 0.059
Echinococcus granulosus calpain 5 0.0297 0.3123 0.887
Schistosoma mansoni ubiquitin-specific peptidase 7 (C19 family) 0.0109 0.0937 0.228
Trypanosoma brucei cysteine peptidase, Clan CA, family C54, putative 0.021 0.2113 0.2113
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0611 0.6789 0.6789
Echinococcus multilocularis calcium transporting ATPase type 2C member 0.0036 0.0085 0.0241
Brugia malayi Cathepsin L-like cysteine proteinase 0.0139 0.1285 0.3365
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.005 0.0247 0.0435
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.023 0.2342 0.2342
Entamoeba histolytica cysteine protease, putative 0.0109 0.0929 0.2783
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0357 0.3822 0.3822
Onchocerca volvulus Cathepsin L homolog 0.0205 0.205 1
Trypanosoma brucei Domain of unknown function (DUF1935), putative 0.0288 0.3022 0.3022
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0079 0.0587 0.0587
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase isozyme 0.0121 0.1073 0.3048
Schistosoma mansoni ubiquitin-specific peptidase 48 (C19 family) 0.005 0.0247 0.0602
Trypanosoma cruzi cysteine peptidase inhibitor, putative 0.0251 0.2594 0.2594
Loa Loa (eye worm) hypothetical protein 0.0038 0.0102 0.0233
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0055 0.0305 0.0867
Leishmania major P-type ATPase, putative 0.004 0.0129 0.0129
Brugia malayi Ubiquitin carboxyl-terminal hydrolase, family 1 protein 0.0134 0.1224 0.3204
Leishmania major inhibitor of cysteine peptidase 0.0251 0.2594 0.2594
Giardia lamblia Cysteine protease 0.0043 0.0164 0.1746
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0234 0.057
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.005 0.0247 0.0647
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 12 0.0081 0.0609 0.1731
Loa Loa (eye worm) cysteine protease 0.0205 0.205 0.5797
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0134 0.1224 0.1224
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0043 0.0164 0.0399
Loa Loa (eye worm) hypothetical protein 0.011 0.094 0.2626
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.005 0.0247 0.0647
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0073 0.0517 0.1149
Schistosoma mansoni family C19 unassigned peptidase (C19 family) 0.0115 0.0997 0.2428
Giardia lamblia Hypothetical protein 0.0043 0.0164 0.1746
Plasmodium falciparum cysteine proteinase falcipain 3 0.0205 0.205 0.5366
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0043 0.0164 0.0399
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.005 0.0247 0.0647
Brugia malayi Papain family cysteine protease containing protein 0.0205 0.205 0.5366
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0611 0.6789 0.6789
Toxoplasma gondii dihydroorotate dehydrogenase reveal, putative 0.0356 0.382 1
Trichomonas vaginalis hypothetical protein 0.0235 0.2401 0.6152
Leishmania major cathepsin L-like protease 0.0357 0.3822 0.3822
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0643 0.716 0.716
Toxoplasma gondii ubiquitin-specific protease USP4 0.005 0.0247 0.0435
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Plasmodium falciparum serine repeat antigen 3 0.0043 0.0164 0.043
Schistosoma mansoni hypothetical protein 0.0182 0.1787 0.435
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0086 0.0667 0.1545
Loa Loa (eye worm) RNA binding protein 0.0068 0.0455 0.1241
Leishmania major D-alanyl-glycyl endopeptidase-like protein,cysteine peptidase, Clan CA, family C51, putative 0.0336 0.3577 0.3577
Brugia malayi Cathepsin L-like precursor 0.0205 0.205 0.5366
Schistosoma mansoni transcription factor LCR-F1 0.0039 0.0111 0.0271
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Brugia malayi cathepsin L-like precursor 0.0139 0.1285 0.3365
Trypanosoma cruzi unspecified product 0.0449 0.4897 0.4897
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-5 0.0288 0.3022 0.3022
Leishmania major D-alanyl-glycyl endopeptidase-like protein,cysteine peptidase, Clan CA, family C51, putative 0.0336 0.3577 0.3577
Echinococcus multilocularis cathepsin b 0.011 0.094 0.267
Toxoplasma gondii cathepsin B 0.011 0.094 0.2289
Loa Loa (eye worm) cathepsin B 0.011 0.094 0.2626
Echinococcus multilocularis Ubiquitin carboxyl terminal hydrolase 48 0.005 0.0247 0.0702
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0205 0.205 0.5219
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0109 0.0929 0.2241
Brugia malayi Peptidase C13 family protein 0.0038 0.01 0.0262
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0205 0.205 0.5219
Echinococcus granulosus Ubiquitin thioesterase otubain protein 0.0092 0.0737 0.2092
Brugia malayi PAS domain containing protein 0.0052 0.0271 0.0708
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.011 0.094 0.2288
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Trypanosoma cruzi pyroglutamyl-peptidase I, putative 0.0462 0.5054 0.5054
Echinococcus multilocularis GPI anchor transamidase 0.0066 0.0425 0.1208
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase isozyme L3 0.0134 0.1224 0.3204
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0677 0.7561 0.7561
Brugia malayi cathepsin F-like cysteine proteinase 0.0066 0.0424 0.1111
Toxoplasma gondii calcium-translocating P-type ATPase, PMCA-type protein 0.0047 0.0214 0.0345
Trypanosoma cruzi trypanothione synthetase 0.0072 0.0505 0.0505
Trypanosoma cruzi kinesin, putative 0.0062 0.0382 0.0382
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0043 0.0164 0.021
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0055 0.0305 0.0813
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0087 0.0674 0.717
Trypanosoma cruzi cysteine peptidase, Clan CA, family C51, putative 0.0336 0.3577 0.3577
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.005 0.0247 0.0677
Echinococcus granulosus cathepsin l1 0.0205 0.205 0.5822
Entamoeba histolytica cysteine protease, putative 0.0109 0.0929 0.2783
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Giardia lamblia Cathepsin B precursor 0.011 0.094 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0677 0.7561 0.7561
Giardia lamblia Cathepsin L-like protease 0.0043 0.0164 0.1746
Echinococcus granulosus 5'partial|Ubiquitin carboxyl terminal hydrolase 48 0.005 0.0247 0.0702
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.004 0.0129 0.0314
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0043 0.0164 0.1746
Loa Loa (eye worm) calcium ATPase 0.0032 0.0028 0.0021
Plasmodium falciparum serine repeat antigen 4 0.0043 0.0164 0.043
Trypanosoma brucei ubiquitin hydrolase, putative 0.0034 0.0061 0.0061
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Trypanosoma brucei calpain-like protein, putative 0.0317 0.3365 0.3365
Giardia lamblia GPI-anchor transamidase, putative 0.0066 0.0425 0.4523
Loa Loa (eye worm) Na,K-ATPase alpha subunit 0.0036 0.0085 0.0183
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0087 0.0674 0.1641
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.004 0.0129 0.0117
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.005 0.0247 0.0435
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0043 0.0164 0.0212
Entamoeba histolytica cysteine protease, putative 0.0109 0.0929 0.2783
Trypanosoma brucei Calpain-like protein 2 0.0658 0.7339 0.7339
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0139 0.1284 0.3185
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0253 0.2611 0.2611
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.021 0.2113 0.2113
Brugia malayi calpain family protein 1 0.0297 0.3123 0.8176
Brugia malayi Cathepsin L-like precursor 0.0205 0.205 0.5366
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.071 0.7945 0.7945
Trypanosoma brucei GPI-anchor transamidase subunit 8 (GPI8) 0.0066 0.0425 0.0425
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0164 0.021
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0205 0.205 0.5219
Giardia lamblia Cathepsin B precursor 0.011 0.094 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Loa Loa (eye worm) hypothetical protein 0.0043 0.0164 0.0409
Leishmania major calpain family cysteine protease-like protein 0.0597 0.6625 0.6625
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0205 0.205 0.5822
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0066 0.0432 0.0432
Trypanosoma brucei calpain, putative 0.0235 0.2401 0.2401
Toxoplasma gondii diphthine synthase, putative 0.0038 0.0102 0.0047
Giardia lamblia Cathepsin B precursor 0.0043 0.0164 0.1746
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0235 0.2401 0.2401
Trypanosoma cruzi major cysteine proteinase, putative 0.0043 0.0164 0.0164
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0357 0.3822 0.3822
Plasmodium falciparum serine repeat antigen 9 0.0043 0.0164 0.043
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0145 0.1348 0.4081
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 0.005 0.0247 0.0702
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0068 0.0455 0.1241
Leishmania major cathepsin L-like protease 0.0205 0.205 0.205
Giardia lamblia Cathepsin L-like protease 0.0043 0.0164 0.1746
Leishmania major otubain, putative,otubain cysteine peptidase, Clan CA, family C65, putative 0.0092 0.0737 0.0737
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 47 0.005 0.0247 0.0702
Echinococcus multilocularis geminin 0.0182 0.1787 0.5076
Trypanosoma cruzi hypothetical protein, conserved 0.0359 0.385 0.385
Onchocerca volvulus 0.0205 0.205 1
Brugia malayi calpain family protein 1 0.0297 0.3123 0.8176
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.005 0.0247 0.0677
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0317 0.3365 0.3365
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase, putative 0.005 0.0247 0.0435
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.005 0.0247 0.0677
Plasmodium vivax hypothetical protein, conserved 0.0072 0.0505 0.1126
Echinococcus multilocularis cysteine protease 0.0205 0.205 0.5822
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0139 0.1284 0.3185
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 16 0.005 0.0247 0.0702
Echinococcus multilocularis ubiquitin specific protease 41 0.0087 0.0674 0.1914
Brugia malayi ubiquitin specific protease 14 0.0079 0.0586 0.1535
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0145 0.1348 0.1348
Trypanosoma brucei conserved protein 0.0231 0.2357 0.2357
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Entamoeba histolytica GPI-anchor transamidase, putative 0.0066 0.0425 0.1227
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase, putative 0.0121 0.1073 0.3231
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.0234 0.0665
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase isozyme 0.0121 0.1073 0.3048
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0499 0.5486 0.5486
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0088 0.0689 0.1677
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0109 0.0929 0.226
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0357 0.3822 0.3822
Brugia malayi cathepsin Z-like cysteine proteinase 0.0043 0.0164 0.043
Giardia lamblia Cathepsin L precursor 0.0043 0.0164 0.1746
Loa Loa (eye worm) hypoxia-induced factor 1 0.0162 0.155 0.4369
Trypanosoma brucei calpain, putative 0.0516 0.5679 0.5679
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0087 0.0674 0.1914
Loa Loa (eye worm) hypothetical protein 0.0043 0.0164 0.0409
Trypanosoma cruzi cysteine proteinase, putative 0.0109 0.0929 0.0929
Loa Loa (eye worm) calpain family protein 1 0.0297 0.3123 0.8864
Leishmania major cathepsin L-like protease 0.0205 0.205 0.205
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0079 0.0586 0.1332
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0611 0.6789 0.6789
Loa Loa (eye worm) hypothetical protein 0.0043 0.0164 0.0409
Trypanosoma brucei trypanothione synthetase 0.0072 0.0505 0.0505
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0288 0.3022 0.3022
Trypanosoma cruzi hypothetical protein, conserved 0.0288 0.3022 0.3022
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0281 0.2938 0.2938
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0297 0.3123 0.7602
Echinococcus multilocularis cathepsin L 0.0109 0.0929 0.2637
Entamoeba histolytica hypothetical protein 0.0039 0.0111 0.0257
Mycobacterium ulcerans dihydroorotate dehydrogenase 2 0.0356 0.382 1
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0164 0.021
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Leishmania major hypothetical protein, conserved 0.0466 0.5098 0.5098
Trypanosoma brucei vacuolar-type Ca2+-ATPase, putative 0.0047 0.0214 0.0214
Entamoeba histolytica diphthine synthase, putative 0.0038 0.0102 0.023
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Plasmodium vivax vivapain-2 0.0205 0.205 0.526
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0084 0.0643 0.0643
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0087 0.0674 0.1764
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0205 0.205 0.5219
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.005 0.0247 0.0647
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0055 0.0305 0.059
Toxoplasma gondii exonuclease 0.0065 0.0421 0.0901
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0357 0.3822 0.3822
Echinococcus granulosus cathepsin L 0.0043 0.0164 0.0466
Loa Loa (eye worm) calpain 5 0.0062 0.0382 0.1031
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0205 0.205 0.5219
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Trichomonas vaginalis cation-transporting ATPase fungi, putative 0.0047 0.0214 0.0342
Trypanosoma cruzi major cysteine proteinase, putative 0.0195 0.1936 0.1936
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Echinococcus granulosus tar DNA binding protein 0.0068 0.0455 0.1292
Loa Loa (eye worm) hypothetical protein 0.0205 0.205 0.5797
Schistosoma mansoni calpain-2 (C02 family) 0.0235 0.2401 0.5845
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0139 0.1284 0.3185
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0145 0.1348 0.1348
Trypanosoma brucei cysteine peptidase, Clan CA, family C51, putative 0.0336 0.3577 0.3577
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0072 0.0505 0.0505
Brugia malayi ubiquitin carboxyl-terminal hydrolase 46 0.0081 0.0609 0.1595
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0081 0.0609 0.0609
Loa Loa (eye worm) fibroinase 0.0205 0.205 0.5797
Brugia malayi Cytochrome P450 family protein 0.0056 0.0317 0.0829
Trypanosoma brucei kinesin, putative 0.0062 0.0382 0.0382
Schistosoma mansoni cathepsin C 0.0043 0.0164 0.0399
Schistosoma mansoni calpain C (C02 family) 0.0297 0.3123 0.7602
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0079 0.0586 0.6239
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0088 0.0689 0.1604
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Trypanosoma cruzi cruzipain precursor, putative 0.0357 0.3822 0.3822
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0523 0.5763 0.5763
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Loa Loa (eye worm) hypothetical protein 0.0043 0.0164 0.0409
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0247 0.0431
Brugia malayi Dihydroorotate dehydrogenase, mitochondrial precursor, putative 0.0356 0.382 1

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) Compound was tested for in vivo activity against 1x 10ex6 CFU of C. albicans C-43 infected mice at dose of 10 mg/kg; Inactive ChEMBL. No reference
Activity (functional) Tested for inhibition of yeast to mycelial transformation against C. albicans C-43 at concentration of <0.03 ug/mL at pH 7.0; Active ChEMBL. No reference
Activity (functional) Tested for inhibition of yeast to mycelial transformation against C. stellatoidea at concentration of <0.03 ug/mL at pH 7.0; Active ChEMBL. No reference
Activity (functional) Tested for inhibition of yeast to mycelial transformation against six strains of C. albicans at concentration of <0.03 ug/mL at pH 7.0; Active ChEMBL. No reference
Activity (functional) = 4.3 Geometri mean CFUs(log 10) for C. albicans infected mice treated with 50 mg/kg of compound ChEMBL. No reference
Activity (functional) 0 Tested for inhibition of yeast to mycelial transformation against six strains of C. albicans at concentration of <0.03 ug/mL at pH 7.0; Active ChEMBL. No reference
Activity (functional) 0 Tested for inhibition of yeast to mycelial transformation against C. albicans C-43 at concentration of <0.03 ug/mL at pH 7.0; Active ChEMBL. No reference
Activity (functional) 0 Tested for inhibition of yeast to mycelial transformation against C. stellatoidea at concentration of <0.03 ug/mL at pH 7.0; Active ChEMBL. No reference
Activity (functional) 0 Compound was tested for in vivo activity against 1x 10ex6 CFU of C. albicans C-43 infected mice at dose of 10 mg/kg; Inactive ChEMBL. No reference
Activity (functional) = 4.3 Geometri mean CFUs(log 10) for C. albicans infected mice treated with 50 mg/kg of compound ChEMBL. No reference
MIC (functional) = 0.5 ug ml-1 Minimum inhibitory concentration against two strains of C. parapsilosis ChEMBL. No reference
Survival (functional) = 100 % Compound was tested for percent survival against C. albicans C-43 at 50 mg/kg (iv) in mice ChEMBL. No reference
Survival (functional) = 100 % Compound was tested for percent survival against C. albicans C-43 at 50 mg/kg (iv) in mice ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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