Detailed information for compound 576113

Basic information

Technical information
  • TDR Targets ID: 576113
  • Name: 1,4-dihydroxy-5,8-bis[2-(2-hydroxyethylamino) ethylamino]anthracene-9,10-dione dihydrochlor ide
  • MW: 517.403 | Formula: C22H30Cl2N4O6
  • H donors: 8 H acceptors: 6 LogP: 2.6 Rotable bonds: 12
    Rule of 5 violations (Lipinski): 3
  • SMILES: OCCNCCNc1ccc(c2c1C(=O)c1c(C2=O)c(O)ccc1O)NCCNCCO.Cl.Cl
  • InChi: 1S/C22H28N4O6.2ClH/c27-11-9-23-5-7-25-13-1-2-14(26-8-6-24-10-12-28)18-17(13)21(31)19-15(29)3-4-16(30)20(19)22(18)32;;/h1-4,23-30H,5-12H2;2*1H
  • InChiKey: ZAHQPTJLOCWVPG-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 1,4-dihydroxy-5,8-bis[2-(2-hydroxyethylamino)ethylamino]-9,10-anthraquinone dihydrochloride
  • Mitoxantrone
  • 65271-80-9
  • 70476-82-3
  • Mitozantrone hydrochloride
  • NSC-301739
  • Onkotrone
  • Ralenova
  • D02166
  • Mitoxantrone hydrochloride (JAN/USP)
  • Novantron (TN)
  • Novantron
  • Prestwick_571
  • MITOXANTHRONE HYDROCHLORIDE
  • LS-20325
  • 1,4-Dihydroxy-5,8-bis((2-((2-hydroxyethyl)amino)ethyl)amino)anthraquinone dihydrochloride
  • 9,10-Anthracenedione, 1,4-dihydroxy-5,8-bis((2-((2-hydroxyethyl)amino)ethyl)amino)-, dihydrochloride
  • ANTHRACENEDIONE, 1,4-DIHYDROXY-5,8-BIS((2-((2-HYDROXYETHYL)AMINO)ETHYL)AMINO)-,
  • CCRIS 2592
  • CL 232315
  • CL-232315
  • DHAD
  • DRG-0102
  • EINECS 274-619-1
  • HSDB 6543
  • Immunex
  • Mitoxantrone dihydrochloride
  • Mitoxantrone hydrochloride
  • Mitoxantrone hydrochloride [USAN:JAN]
  • NSC 301739
  • Novantrone
  • NCGC00094116-02
  • NCGC00094116-03
  • NCGC00094116-04
  • 1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9,10-anthracenedione dihydrochloride
  • M6545_SIGMA
  • EU-0100779
  • SPECTRUM1503278
  • Eslep

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens RAD52 homolog (S. cerevisiae) Starlite/ChEMBL No references
Homo sapiens androgen receptor Starlite/ChEMBL No references
Homo sapiens tumor protein p53 Starlite/ChEMBL No references
Homo sapiens isocitrate dehydrogenase 1 (NADP+), soluble Starlite/ChEMBL No references
Homo sapiens survival of motor neuron 2, centromeric Starlite/ChEMBL No references
Homo sapiens lysine (K)-specific demethylase 4A Starlite/ChEMBL No references
Homo sapiens Pim-1 proto-oncogene, serine/threonine kinase Starlite/ChEMBL References
Homo sapiens bromodomain adjacent to zinc finger domain, 2B Starlite/ChEMBL No references
Giardia intestinalis Putative fructose-1,6-bisphosphate aldolase Starlite/ChEMBL No references
Escherichia coli endonuclease IV with intrinsic 3'-5' exonuclease activity Starlite/ChEMBL No references
Homo sapiens Rac GTPase activating protein 1 Starlite/ChEMBL No references
Homo sapiens core-binding factor, beta subunit No references
Influenza A virus Nonstructural protein 1 Starlite/ChEMBL No references
Mycobacterium tuberculosis Transmembrane serine/threonine-protein kinase B PknB (protein kinase B) (STPK B) Curated by TDR Targets References
Homo sapiens jun proto-oncogene Starlite/ChEMBL No references
Equus caballus Ferritin light chain Starlite/ChEMBL No references
Homo sapiens N-methylpurine-DNA glycosylase Starlite/ChEMBL References
Homo sapiens l(3)mbt-like 1 (Drosophila) Starlite/ChEMBL No references
Homo sapiens mechanistic target of rapamycin (serine/threonine kinase) Starlite/ChEMBL No references
Homo sapiens chromobox homolog 1 Starlite/ChEMBL No references
Homo sapiens multiple endocrine neoplasia I No references
Homo sapiens polymerase (DNA directed), beta Starlite/ChEMBL No references
Homo sapiens geminin, DNA replication inhibitor Starlite/ChEMBL No references
Homo sapiens muscleblind-like splicing regulator 1 Starlite/ChEMBL No references
Homo sapiens flap structure-specific endonuclease 1 Starlite/ChEMBL No references
Homo sapiens mitogen-activated protein kinase 1 Starlite/ChEMBL No references
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references
Homo sapiens synuclein, alpha (non A4 component of amyloid precursor) Starlite/ChEMBL No references
Homo sapiens SMAD family member 2 Starlite/ChEMBL No references
Photinus pyralis Luciferin 4-monooxygenase Starlite/ChEMBL No references
Homo sapiens Bloom syndrome, RecQ helicase-like Starlite/ChEMBL No references
Mus musculus RAR-related orphan receptor gamma Starlite/ChEMBL No references
Homo sapiens M-phase phosphoprotein 8 Starlite/ChEMBL No references
Homo sapiens ataxin 2 Starlite/ChEMBL No references
Homo sapiens Werner syndrome, RecQ helicase-like Starlite/ChEMBL No references
Homo sapiens lamin A/C Starlite/ChEMBL No references
Homo sapiens euchromatic histone-lysine N-methyltransferase 2 Starlite/ChEMBL No references
Homo sapiens paired box 8 Starlite/ChEMBL No references
Homo sapiens arachidonate 15-lipoxygenase, type B Starlite/ChEMBL No references
Homo sapiens polymerase (DNA directed) kappa Starlite/ChEMBL No references
Homo sapiens runt-related transcription factor 1 Starlite/ChEMBL No references
Homo sapiens polymerase (DNA directed) iota Starlite/ChEMBL No references
Homo sapiens APEX nuclease (multifunctional DNA repair enzyme) 1 Starlite/ChEMBL No references
Homo sapiens neuropeptide S receptor 1 Starlite/ChEMBL No references
Homo sapiens tyrosyl-DNA phosphodiesterase 1 Starlite/ChEMBL No references
Photuris pennsylvanica Luciferase Starlite/ChEMBL No references
Homo sapiens polymerase (DNA directed), eta Starlite/ChEMBL No references
Homo sapiens microtubule-associated protein tau Starlite/ChEMBL No references
Homo sapiens peroxisome proliferator-activated receptor delta Starlite/ChEMBL No references
Homo sapiens lysine (K)-specific methyltransferase 2A Starlite/ChEMBL No references
Homo sapiens vitamin D (1,25- dihydroxyvitamin D3) receptor Starlite/ChEMBL No references
Homo sapiens ATPase family, AAA domain containing 5 Starlite/ChEMBL No references
Rattus norvegicus Inositol monophosphatase 1 Starlite/ChEMBL No references
Rattus norvegicus Dual specificity tyrosine-phosphorylation-regulated kinase 1A Starlite/ChEMBL No references
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references
Mycobacterium leprae Probable transmembrane serine/threonine-protein kinase B PknB (protein kinase B) (STPK B) Curated by TDR Targets References
Homo sapiens RecQ helicase-like Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) ATP-dependent DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127212 All targets in OG5_127212
Trypanosoma brucei gambiense serine/threonine-protein kinase, putative,protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Schistosoma japonicum FKBP12-rapamycin complex-associated protein, putative Get druggable targets OG5_127212 All targets in OG5_127212
Trypanosoma congolense Phosphatidylinositol 3-kinase tor2 Get druggable targets OG5_127212 All targets in OG5_127212
Brugia malayi RhoGAP domain containing protein Get druggable targets OG5_132551 All targets in OG5_132551
Trypanosoma brucei gambiense DNA polymerase kappa, putative,DNA polymerase IV, putative Get druggable targets OG5_127393 All targets in OG5_127393
Echinococcus multilocularis FKBP12 rapamycin complex associated protein Get druggable targets OG5_127212 All targets in OG5_127212
Plasmodium falciparum flap endonuclease 1 Get druggable targets OG5_127472 All targets in OG5_127472
Brugia malayi Bloom's syndrome protein homolog Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus granulosus lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase Get druggable targets OG5_129037 All targets in OG5_129037
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Trichomonas vaginalis DNA-3-methyladenine glycosylase, putative Get druggable targets OG5_130143 All targets in OG5_130143
Schistosoma japonicum ko:K04371 extracellular signal-regulated kinase 1/2, putative Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Leishmania donovani Phosphatidylinositol 3-kinase tor2 Get druggable targets OG5_127212 All targets in OG5_127212
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127901 All targets in OG5_127901
Leishmania mexicana mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Leishmania major target of rapamycin (TOR) kinase 2, putative Get druggable targets OG5_127212 All targets in OG5_127212
Echinococcus multilocularis Rac GTPase activating protein 1 Get druggable targets OG5_132551 All targets in OG5_132551
Schistosoma japonicum IPR000276,Rhodopsin-like GPCR superfamily,domain-containing Get druggable targets OG5_136011 All targets in OG5_136011
Brugia malayi Inositol-1 Get druggable targets OG5_126810 All targets in OG5_126810
Leishmania infantum DNA polymerase kappa, putative,DNA polymerase IV, putative Get druggable targets OG5_127393 All targets in OG5_127393
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) pax transcription factor protein 2 Get druggable targets OG5_139945 All targets in OG5_139945
Loa Loa (eye worm) CAMK/PIM protein kinase Get druggable targets OG5_134863 All targets in OG5_134863
Leishmania infantum flap endonuclease-1 (FEN-1), putative Get druggable targets OG5_127472 All targets in OG5_127472
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis muscleblind protein 1 Get druggable targets OG5_132352 All targets in OG5_132352
Leishmania braziliensis tyrosyl-DNA phosphodiesterase, putative;with=GeneDB:LinJ33_V3.3210 Get druggable targets OG5_129037 All targets in OG5_129037
Trypanosoma congolense mitochondrial DNA polymerase beta, putative Get druggable targets OG5_130965 All targets in OG5_130965
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein Get druggable targets OG5_127393 All targets in OG5_127393
Giardia lamblia DNA repair protein RAD52 Get druggable targets OG5_130806 All targets in OG5_130806
Onchocerca volvulus Get druggable targets OG5_133916 All targets in OG5_133916
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Leishmania donovani mitogen-activated protein kinase 4 Get druggable targets OG5_126781 All targets in OG5_126781
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum expressed protein Get druggable targets OG5_127917 All targets in OG5_127917
Plasmodium knowlesi isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans frameshifted from upsteam TOR2 CDS (CaP19.9461) Get druggable targets OG5_127212 All targets in OG5_127212
Schistosoma japonicum expressed protein Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma mansoni mixed-lineage leukemia protein mll Get druggable targets OG5_130642 All targets in OG5_130642
Theileria parva flap endonuclease 1, putative Get druggable targets OG5_127472 All targets in OG5_127472
Trypanosoma congolense tyrosyl-DNA Phosphodiesterase (Tdp1), putative Get druggable targets OG5_129037 All targets in OG5_129037
Plasmodium falciparum ATP-dependent DNA helicase Q1 Get druggable targets OG5_126644 All targets in OG5_126644
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Plasmodium knowlesi apurinic/apyrimidinic endonuclease Apn1, putative Get druggable targets OG5_129467 All targets in OG5_129467
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus dnaJ subfamily B Get druggable targets OG5_133913 All targets in OG5_133913
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128521 All targets in OG5_128521
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis arachidonate 5 lipoxygenase Get druggable targets OG5_127482 All targets in OG5_127482
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus multilocularis transcription factor Dp 1 Get druggable targets OG5_129037 All targets in OG5_129037
Plasmodium falciparum DNA-3-methyladenine glycosylase, putative Get druggable targets OG5_130143 All targets in OG5_130143
Loa Loa (eye worm) MH2 domain-containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum M-phase phosphoprotein 8, putative Get druggable targets OG5_136365 All targets in OG5_136365
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni flap endonuclease-1 Get druggable targets OG5_127472 All targets in OG5_127472
Loa Loa (eye worm) jmjC domain-containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus multilocularis neuropeptide receptor A26 Get druggable targets OG5_136011 All targets in OG5_136011
Echinococcus multilocularis bloom syndrome protein Get druggable targets OG5_126644 All targets in OG5_126644
Theileria parva hypothetical protein Get druggable targets OG5_129545 All targets in OG5_129545
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Trypanosoma brucei gambiense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania mexicana isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania mexicana mitogen-activated protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Candida albicans similar to N terminal region of S. cerevisiae TOR2 (YKL203C) and TOR1 (YJR066W) putative protein/phosphatidylinositol kinases in Get druggable targets OG5_127212 All targets in OG5_127212
Leishmania donovani serine/threonine-protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Cryptosporidium hominis MAPK Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus granulosus dna polymerase kappa Get druggable targets OG5_127393 All targets in OG5_127393
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) Get druggable targets OG5_129467 All targets in OG5_129467
Candida albicans N terminus of cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative Get druggable targets OG5_129037 All targets in OG5_129037
Trypanosoma cruzi DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Leishmania mexicana DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative Get druggable targets OG5_126810 All targets in OG5_126810
Theileria parva isocitrate dehydrogenase (NADP+), putative Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania mexicana DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Trichomonas vaginalis DNA helicase recq, putative Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma congolense DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Trichomonas vaginalis chromobox protein, putative Get druggable targets OG5_129545 All targets in OG5_129545
Echinococcus multilocularis chromobox protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Schistosoma japonicum ko:K00461 arachidonate 5-lipoxygenase [EC1.13.11.34], putative Get druggable targets OG5_127482 All targets in OG5_127482
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 Get druggable targets OG5_127212 All targets in OG5_127212
Candida albicans DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania major mitogen activated protein kinase, putative,map kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania donovani flap endonuclease-1 (FEN-1), putative Get druggable targets OG5_127472 All targets in OG5_127472
Neospora caninum hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 Get druggable targets OG5_126781 All targets in OG5_126781
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus multilocularis jun protein Get druggable targets OG5_131442 All targets in OG5_131442
Leishmania braziliensis DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Candida albicans Serine/threonine protein kinase of MAP kinase family Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma brucei DNA polymerase IV, putative Get druggable targets OG5_127393 All targets in OG5_127393
Babesia bovis ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Brugia malayi isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Giardia lamblia Sgs1 DNA helicase, putative Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Giardia lamblia GTOR Get druggable targets OG5_127212 All targets in OG5_127212
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative Get druggable targets OG5_127393 All targets in OG5_127393
Echinococcus multilocularis Transcription factor, JmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma japonicum ko:K00031 isocitrate dehydrogenase [EC1.1.1.42], putative Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) phosphatidylinositol 3 Get druggable targets OG5_127212 All targets in OG5_127212
Trypanosoma congolense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans C terminus of cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Theileria parva hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Treponema pallidum ATP-dependent DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma brucei gambiense flap endonuclease-1 (FEN-1), putative Get druggable targets OG5_127472 All targets in OG5_127472
Echinococcus multilocularis survival motor neuron protein 1 Get druggable targets OG5_132873 All targets in OG5_132873
Toxoplasma gondii target of rapamycin (TOR), putative Get druggable targets OG5_127212 All targets in OG5_127212
Mycobacterium tuberculosis Transmembrane serine/threonine-protein kinase B PknB (protein kinase B) (STPK B) Get druggable targets OG5_146588 All targets in OG5_146588
Echinococcus granulosus ATP dependent DNA helicase Q1 Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium knowlesi acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi MAP kinase sur-1 Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania braziliensis target of rapamycin (TOR) kinase 2, putative Get druggable targets OG5_127212 All targets in OG5_127212
Leishmania infantum serine/threonine-protein kinase, putative,protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus chromobox protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Plasmodium berghei ADP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Trichomonas vaginalis myo inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Leishmania infantum DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Candida albicans cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Theileria parva hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma cruzi mitogen activated protein kinase 2, putative Get druggable targets OG5_126781 All targets in OG5_126781
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Echinococcus multilocularis isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127393 All targets in OG5_127393
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative Get druggable targets OG5_129467 All targets in OG5_129467
Echinococcus multilocularis endonuclease exonuclease phosphatase Get druggable targets OG5_130415 All targets in OG5_130415
Echinococcus multilocularis lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma brucei gambiense isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) intermediate filament tail domain-containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma brucei phosphatidylinositol 4-kinase, putative Get druggable targets OG5_127212 All targets in OG5_127212
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum target of rapamycin (TOR) kinase 1, putative Get druggable targets OG5_127212 All targets in OG5_127212
Echinococcus granulosus muscleblind protein Get druggable targets OG5_132352 All targets in OG5_132352
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi ImpB/MucB/SamB family protein Get druggable targets OG5_128521 All targets in OG5_128521
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative Get druggable targets OG5_130965 All targets in OG5_130965
Plasmodium falciparum acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma japonicum Menin, putative Get druggable targets OG5_133913 All targets in OG5_133913
Onchocerca volvulus Heterochromatin protein 1 homolog Get druggable targets OG5_129545 All targets in OG5_129545
Leishmania infantum mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative Get druggable targets OG5_130965 All targets in OG5_130965
Trypanosoma cruzi mitogen-activated protein kinase 11, putative Get druggable targets OG5_126781 All targets in OG5_126781
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Mycobacterium tuberculosis Conserved hypothetical protein Get druggable targets OG5_130965 All targets in OG5_130965
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Candida albicans MAP kinase implicated in PKC1-controlled signalling pathway Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma congolense Phosphatidylinositol 3-kinase tor1 Get druggable targets OG5_127212 All targets in OG5_127212
Mycobacterium tuberculosis Probable DNA polymerase IV DinX (pol IV 1) (DNA nucleotidyltransferase (DNA-directed)) Get druggable targets OG5_127393 All targets in OG5_127393
Leishmania mexicana phosphatidylinositol 3-kinase (tor2)-like protein Get druggable targets OG5_127212 All targets in OG5_127212
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni bromodomain containing protein Get druggable targets OG5_131570 All targets in OG5_131570
Schistosoma mansoni DNA polymerase eta Get druggable targets OG5_128521 All targets in OG5_128521
Schistosoma mansoni intermediate filament proteins Get druggable targets OG5_128723 All targets in OG5_128723
Theileria parva apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_129467 All targets in OG5_129467
Echinococcus multilocularis proto oncogene serine:threonine protein kinase Get druggable targets OG5_134863 All targets in OG5_134863
Neospora caninum hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis chromobox protein, putative Get druggable targets OG5_129545 All targets in OG5_129545
Trypanosoma brucei gambiense DNA polymerase kappa, putative,DNA polymerase IV, putative Get druggable targets OG5_127393 All targets in OG5_127393
Trypanosoma congolense flap endonuclease-1 (FEN-1), putative Get druggable targets OG5_127472 All targets in OG5_127472
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Echinococcus multilocularis bromodomain adjacent to zinc finger domain Get druggable targets OG5_131570 All targets in OG5_131570
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Neospora caninum hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Theileria parva DNA helicase, putative Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum Chromobox protein homolog 5, putative Get druggable targets OG5_129545 All targets in OG5_129545
Brugia malayi M-phase phosphoprotein, mpp8 Get druggable targets OG5_136365 All targets in OG5_136365
Schistosoma japonicum FKBP12-rapamycin complex-associated protein, putative Get druggable targets OG5_127212 All targets in OG5_127212
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Candida albicans similar to S. cerevisiae RAD52 (YML032C) dsDNA break repair annealing factor Get druggable targets OG5_130806 All targets in OG5_130806
Schistosoma japonicum expressed protein Get druggable targets OG5_131570 All targets in OG5_131570
Schistosoma japonicum ko:K03511 DNA polymerase kappa subunit, putative Get druggable targets OG5_127393 All targets in OG5_127393
Leishmania major DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Plasmodium knowlesi ATP-dependent DNA helicase Q1, putative Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum ko:K01113 phosphodiesterase/alkaline phosphatase D [EC3.1.4.1], putative Get druggable targets OG5_129037 All targets in OG5_129037
Trypanosoma brucei gambiense ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 Get druggable targets OG5_129037 All targets in OG5_129037
Loa Loa (eye worm) transcription factor SMAD2 Get druggable targets OG5_131716 All targets in OG5_131716
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Mycobacterium ulcerans 3-methyladenine DNA glycosylase Get druggable targets OG5_130143 All targets in OG5_130143
Brugia malayi Isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania major target of rapamycin (TOR) kinase 1, putative Get druggable targets OG5_127212 All targets in OG5_127212
Echinococcus multilocularis chromobox protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Entamoeba histolytica recQ family DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma cruzi CMGC/DYRK protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Schistosoma japonicum Lethal(3)malignant brain tumor-like 4 protein, putative Get druggable targets OG5_130415 All targets in OG5_130415
Schistosoma japonicum Probable JmjC domain-containing histone demethylation protein 3B, putative Get druggable targets OG5_127917 All targets in OG5_127917
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma brucei gambiense DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma brucei gambiense phosphatidylinositol 3 kinase, putative Get druggable targets OG5_127212 All targets in OG5_127212
Echinococcus multilocularis dna polymerase eta Get druggable targets OG5_128521 All targets in OG5_128521
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 Get druggable targets OG5_127212 All targets in OG5_127212
Schistosoma japonicum Lamin-C, putative Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni lipoxygenase Get druggable targets OG5_127482 All targets in OG5_127482
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Trypanosoma brucei gambiense mitogen-activated protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Candida albicans DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum Cleft lip and palate transmembrane protein 1-like protein, putative Get druggable targets OG5_131570 All targets in OG5_131570
Leishmania mexicana ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Brugia malayi polk-prov protein Get druggable targets OG5_127393 All targets in OG5_127393
Neospora caninum Isocitrate dehydrogenase-like protein, related Get druggable targets OG5_127057 All targets in OG5_127057
Mycobacterium ulcerans hypothetical protein Get druggable targets OG5_130965 All targets in OG5_130965
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Babesia bovis XPG N-terminal domain and XPG I-region domain containing protein Get druggable targets OG5_127472 All targets in OG5_127472
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative Get druggable targets OG5_129037 All targets in OG5_129037
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Schistosoma mansoni rac gtpase activating protein Get druggable targets OG5_132551 All targets in OG5_132551
Echinococcus multilocularis muscleblind protein Get druggable targets OG5_132352 All targets in OG5_132352
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative Get druggable targets OG5_129037 All targets in OG5_129037
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Wolbachia endosymbiont of Brugia malayi 3-methyladenine DNA glycosylase Get druggable targets OG5_130143 All targets in OG5_130143
Plasmodium yoelii ATP-dependent DNA helicase-related Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma cruzi isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma japonicum ko:K03509 DNA polymerase eta subunit, putative Get druggable targets OG5_128521 All targets in OG5_128521
Entamoeba histolytica hypothetical protein Get druggable targets OG5_127901 All targets in OG5_127901
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Giardia lamblia Fructose-bisphosphate aldolase Get druggable targets OG5_129214 All targets in OG5_129214
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma brucei gambiense tyrosyl-DNA Phosphodiesterase (Tdp1), putative Get druggable targets OG5_129037 All targets in OG5_129037
Echinococcus granulosus jun protein Get druggable targets OG5_131442 All targets in OG5_131442
Echinococcus multilocularis cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132551 All targets in OG5_132551
Brugia malayi bZIP transcription factor family protein Get druggable targets OG5_131442 All targets in OG5_131442
Loa Loa (eye worm) pre-SET domain-containing protein family protein Get druggable targets OG5_131470 All targets in OG5_131470
Leishmania mexicana mitogen activated protein kinase, putative,map kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana Get druggable targets OG5_128521 All targets in OG5_128521
Cryptosporidium parvum RecQ bloom helicase (RNA helicase+hrdc) Get druggable targets OG5_126644 All targets in OG5_126644
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129545 All targets in OG5_129545
Leishmania infantum ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus granulosus mitogen activated protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus multilocularis dual specificity Get druggable targets OG5_127901 All targets in OG5_127901
Brugia malayi Heterochromatin protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Brugia malayi jmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Leishmania major mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Echinococcus multilocularis dnaJ subfamily B Get druggable targets OG5_133913 All targets in OG5_133913
Plasmodium vivax DNA-3-methyladenine glycosylase, putative Get druggable targets OG5_130143 All targets in OG5_130143
Leishmania mexicana flap endonuclease-1 (FEN-1), putative Get druggable targets OG5_127472 All targets in OG5_127472
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Schistosoma japonicum Rac GTPase-activating protein 1, putative Get druggable targets OG5_132551 All targets in OG5_132551
Loa Loa (eye worm) flap endonuclease-1 Get druggable targets OG5_127472 All targets in OG5_127472
Echinococcus granulosus neuropeptide receptor A26 Get druggable targets OG5_136011 All targets in OG5_136011
Echinococcus granulosus dual specificity Get druggable targets OG5_127901 All targets in OG5_127901
Leishmania braziliensis flap endonuclease-1 (FEN-1), putative Get druggable targets OG5_127472 All targets in OG5_127472
Echinococcus multilocularis neuropeptide s receptor Get druggable targets OG5_136011 All targets in OG5_136011
Leishmania donovani tyrosyl-DNA phosphodiesterase-like protein Get druggable targets OG5_129037 All targets in OG5_129037
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131442 All targets in OG5_131442
Neospora caninum Pc21g17280 protein, related Get druggable targets OG5_128521 All targets in OG5_128521
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Loa Loa (eye worm) heterochromatin protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Trichomonas vaginalis DNA polymerase eta, putative Get druggable targets OG5_127393 All targets in OG5_127393
Trypanosoma brucei CMGC/DYRK protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Brugia malayi ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Giardia lamblia Rho GAP, putative Get druggable targets OG5_132551 All targets in OG5_132551
Wolbachia endosymbiont of Brugia malayi exonuclease III Get druggable targets OG5_126768 All targets in OG5_126768
Onchocerca volvulus Get druggable targets OG5_136365 All targets in OG5_136365
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania donovani myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative Get druggable targets OG5_129037 All targets in OG5_129037
Trypanosoma cruzi DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Brugia malayi Flap endonuclease-1 Get druggable targets OG5_127472 All targets in OG5_127472
Mycobacterium ulcerans endonuclease IV Get druggable targets OG5_129467 All targets in OG5_129467
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Leishmania major DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Schistosoma japonicum ko:K10771 AP endonuclease 1, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum Lethal(3)malignant brain tumor-like 3 protein, putative Get druggable targets OG5_130415 All targets in OG5_130415
Schistosoma japonicum ko:K10772 AP endonuclease 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis Ankyrin repeat domain containing protein Get druggable targets OG5_136365 All targets in OG5_136365
Echinococcus granulosus tumor protein p63 Get druggable targets OG5_140038 All targets in OG5_140038
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Brugia malayi Bromodomain containing protein Get druggable targets OG5_131570 All targets in OG5_131570
Giardia lamblia DINP protein human, muc B family Get druggable targets OG5_127393 All targets in OG5_127393
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Trypanosoma brucei gambiense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma japonicum expressed protein Get druggable targets OG5_132551 All targets in OG5_132551
Plasmodium yoelii flap endonuclease-1-related Get druggable targets OG5_127472 All targets in OG5_127472
Plasmodium berghei DNA-3-methyladenine glycosylase, putative Get druggable targets OG5_130143 All targets in OG5_130143
Neospora caninum Multidomain chromatinic protein with the following architecture: 3x PHD-bromo-3xPHD-SET domain and associated cysteine cluster a Get druggable targets OG5_130642 All targets in OG5_130642
Trichomonas vaginalis set domain proteins, putative Get druggable targets OG5_131470 All targets in OG5_131470
Echinococcus multilocularis ATP dependent DNA helicase Q5 Get druggable targets OG5_126644 All targets in OG5_126644
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Trypanosoma cruzi DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Schistosoma japonicum Mitogen-activated protein kinase 3, putative Get druggable targets OG5_126781 All targets in OG5_126781
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma congolense DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Candida albicans apurinic/apyrimidinic endonuclease/3'-repair diesterase Get druggable targets OG5_129467 All targets in OG5_129467
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase Get druggable targets OG5_127901 All targets in OG5_127901
Schistosoma mansoni chromobox protein Get druggable targets OG5_129545 All targets in OG5_129545
Trypanosoma cruzi mitogen activated protein kinase 4, putative Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Loa Loa (eye worm) exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Entamoeba histolytica acyl-coA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_127901 All targets in OG5_127901
Plasmodium yoelii ATP-dependent DNA helicase recQ-related Get druggable targets OG5_126644 All targets in OG5_126644
Plasmodium yoelii AP endonuclease 1 Get druggable targets OG5_129467 All targets in OG5_129467
Leishmania major tyrosyl-DNA phosphodiesterase 1 Get druggable targets OG5_129037 All targets in OG5_129037
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative Get druggable targets OG5_127212 All targets in OG5_127212
Schistosoma japonicum ko:K04799 flap endonuclease-1, putative Get druggable targets OG5_127472 All targets in OG5_127472
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127901 All targets in OG5_127901
Schistosoma mansoni multiple ankyrin repeats single kh domain protein Get druggable targets OG5_136365 All targets in OG5_136365
Plasmodium berghei ATP-dependent DNA helicase Q1, putative Get druggable targets OG5_126644 All targets in OG5_126644
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132873 All targets in OG5_132873
Candida albicans Mitochondrial NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania braziliensis mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440,map kinase Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma mansoni multiple ankyrin repeats single kh domain protein Get druggable targets OG5_136365 All targets in OG5_136365
Echinococcus granulosus endonuclease exonuclease phosphatase Get druggable targets OG5_130415 All targets in OG5_130415
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 Get druggable targets OG5_127212 All targets in OG5_127212
Trypanosoma congolense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein Get druggable targets OG5_129037 All targets in OG5_129037
Loa Loa (eye worm) intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Onchocerca volvulus Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma congolense inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related Get druggable targets OG5_127212 All targets in OG5_127212
Trypanosoma cruzi DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Leishmania infantum isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Onchocerca volvulus Get druggable targets OG5_129545 All targets in OG5_129545
Schistosoma mansoni blooms syndrome DNA helicase Get druggable targets OG5_126644 All targets in OG5_126644
Neospora caninum hypothetical protein Get druggable targets OG5_127057 All targets in OG5_127057
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase Get druggable targets OG5_126810 All targets in OG5_126810
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Toxoplasma gondii flap structure-specific endonuclease 1, putative Get druggable targets OG5_127472 All targets in OG5_127472
Cryptosporidium parvum flap endonuclease 1 Get druggable targets OG5_127472 All targets in OG5_127472
Trypanosoma brucei gambiense DNA polymerase kappa, putative,DNA polymerase IV, putative Get druggable targets OG5_127393 All targets in OG5_127393
Mycobacterium leprae Probable transmembrane serine/threonine-protein kinase B PknB (protein kinase B) (STPK B) Get druggable targets OG5_146588 All targets in OG5_146588
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma brucei gambiense phosphatidylinositol 3-kinase tor, putative Get druggable targets OG5_127212 All targets in OG5_127212
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Candida albicans similar to internal region of S. cerevisiae TOR2 (YKL203C) and TOR1 (YJR066W) protein/phosphatidylinositol kinases involved in n Get druggable targets OG5_127212 All targets in OG5_127212
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Candida albicans MAP kinase-like orf Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum Conserved hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Echinococcus granulosus survival motor neuron protein 1 Get druggable targets OG5_132873 All targets in OG5_132873
Leishmania braziliensis ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Babesia bovis isocitrate dehydrogenase, NADP-dependent family protein Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium knowlesi DNA-3-methyladenine glycosylase, putative Get druggable targets OG5_130143 All targets in OG5_130143
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Plasmodium knowlesi ADP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Schistosoma mansoni DNA helicase recq1 Get druggable targets OG5_126644 All targets in OG5_126644
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_134863 All targets in OG5_134863
Mycobacterium tuberculosis Possible 3-methyladenine DNA glycosylase Mpg Get druggable targets OG5_130143 All targets in OG5_130143
Schistosoma japonicum ko:K04702 proto-oncogene serine/threonine-protein kinase Pim-1, putative Get druggable targets OG5_134863 All targets in OG5_134863
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Candida albicans similar to internal region of S. cerevisiae TOR2 (YKL203C) and TOR1 (YJR066W) protein/phosphatidylinositol kinases involved in n Get druggable targets OG5_127212 All targets in OG5_127212
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Plasmodium yoelii putative AP endonuclease-related Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) inositol-1 Get druggable targets OG5_126810 All targets in OG5_126810
Cryptosporidium hominis flap endonuclease 1 Get druggable targets OG5_127472 All targets in OG5_127472
Schistosoma mansoni chromobox protein Get druggable targets OG5_129545 All targets in OG5_129545
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus granulosus cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma congolense serine/threonine-protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Leishmania mexicana serine/threonine-protein kinase, putative,protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Plasmodium knowlesi flap endonuclease 1, putative Get druggable targets OG5_127472 All targets in OG5_127472
Echinococcus granulosus flap endonuclease 1 Get druggable targets OG5_127472 All targets in OG5_127472
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative Get druggable targets OG5_146588 All targets in OG5_146588
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis myo inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Echinococcus granulosus Ankyrin repeat domain containing protein Get druggable targets OG5_136365 All targets in OG5_136365
Trichomonas vaginalis inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Leishmania donovani mitogen activated protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Echinococcus granulosus FKBP12 rapamycin complex associated protein Get druggable targets OG5_127212 All targets in OG5_127212
Leishmania mexicana DNA polymerase kappa, putative,DNA polymerase IV, putative Get druggable targets OG5_127393 All targets in OG5_127393
Giardia lamblia Endonuclease/Exonuclease/phosphatase Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei gambiense DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Trypanosoma cruzi DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Schistosoma japonicum FKBP12-rapamycin complex-associated protein, putative Get druggable targets OG5_127212 All targets in OG5_127212
Leishmania braziliensis DNA polymerase kappa, putative,DNA polymerase IV, putative Get druggable targets OG5_127393 All targets in OG5_127393
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Brugia malayi hypothetical protein Get druggable targets OG5_133916 All targets in OG5_133916
Plasmodium berghei apurinic/apyrimidinic endonuclease Apn1, putative Get druggable targets OG5_129467 All targets in OG5_129467
Mycobacterium ulcerans DNA polymerase IV Get druggable targets OG5_127393 All targets in OG5_127393
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Candida albicans Serine/threonine protein kinase of MAP kinase family Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Echinococcus multilocularis mitogen activated protein kinase 3 Get druggable targets OG5_126781 All targets in OG5_126781
Plasmodium falciparum ADP-dependent DNA helicase RecQ Get druggable targets OG5_126644 All targets in OG5_126644
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Echinococcus granulosus inositol monophosphatase 1 Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma brucei gambiense protein kinase, putative,tyrosine protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma mansoni NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Entamoeba histolytica protein kinase domain containing protein Get druggable targets OG5_127901 All targets in OG5_127901
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein Get druggable targets OG5_127212 All targets in OG5_127212
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Brugia malayi Muscleblind-like protein Get druggable targets OG5_132352 All targets in OG5_132352
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Onchocerca volvulus Get druggable targets OG5_139945 All targets in OG5_139945
Echinococcus multilocularis dna polymerase kappa Get druggable targets OG5_127393 All targets in OG5_127393
Trypanosoma brucei protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Plasmodium yoelii hypothetical protein Get druggable targets OG5_127917 All targets in OG5_127917
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). Get druggable targets OG5_126810 All targets in OG5_126810
Leishmania braziliensis myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Brugia malayi hypothetical protein Get druggable targets OG5_136365 All targets in OG5_136365
Brugia malayi Pre-SET motif family protein Get druggable targets OG5_131470 All targets in OG5_131470
Toxoplasma gondii histone lysine methyltransferase SET1 Get druggable targets OG5_130642 All targets in OG5_130642
Schistosoma mansoni tyrosyl-DNA phosphodiesterase Get druggable targets OG5_129037 All targets in OG5_129037
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Treponema pallidum fructose-bisphosphate aldolase Get druggable targets OG5_129214 All targets in OG5_129214
Leishmania major flap endonuclease-1 (FEN-1), putative Get druggable targets OG5_127472 All targets in OG5_127472
Trypanosoma cruzi apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Echinococcus granulosus arachidonate 5 lipoxygenase Get druggable targets OG5_127482 All targets in OG5_127482
Onchocerca volvulus Serine\/threonine protein kinase homolog Get druggable targets OG5_134863 All targets in OG5_134863
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133916 All targets in OG5_133916
Mycobacterium leprae POSSIBLE 3-METHYLADENINE DNA GLYCOSYLASE MPG Get druggable targets OG5_130143 All targets in OG5_130143
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative Get druggable targets OG5_127472 All targets in OG5_127472
Trypanosoma congolense tyrosine protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase Get druggable targets OG5_129467 All targets in OG5_129467
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB Get druggable targets OG5_126810 All targets in OG5_126810
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) Get druggable targets OG5_129467 All targets in OG5_129467
Schistosoma japonicum IPR000437,Prokaryotic membrane lipoprotein lipid attachment site;IPR008936,Rho GTPase activation protein,domain-containing Get druggable targets OG5_132551 All targets in OG5_132551
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127917 All targets in OG5_127917
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus granulosus neuropeptide s receptor Get druggable targets OG5_136011 All targets in OG5_136011
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative Get druggable targets OG5_146588 All targets in OG5_146588
Treponema pallidum exodeoxyribonuclease (exoA) Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum ko:K01092 myo-inositol-1(or 4)-monophosphatase [EC3.1.3.25], putative Get druggable targets OG5_126810 All targets in OG5_126810
Trichomonas vaginalis DNA helicase recq, putative Get druggable targets OG5_126644 All targets in OG5_126644
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132352 All targets in OG5_132352
Brugia malayi ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Leishmania donovani ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Candida albicans frameshifted from upstream TOR2 CDS (CaP19.1905) Get druggable targets OG5_127212 All targets in OG5_127212
Toxoplasma gondii isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei gambiense inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Leishmania braziliensis 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum Intermediate filament protein ifa-1, putative Get druggable targets OG5_128723 All targets in OG5_128723
Mycobacterium ulcerans hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus granulosus intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania braziliensis apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni inositol monophosphatase Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Schistosoma mansoni DNA helicase recq5 Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus granulosus Transcription factor JmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni hypothetical protein Get druggable targets OG5_130415 All targets in OG5_130415
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129467 All targets in OG5_129467
Schistosoma mansoni microtubule-associated protein tau Get druggable targets OG5_133504 All targets in OG5_133504
Cryptosporidium hominis hypothetical protein Get druggable targets OG5_129037 All targets in OG5_129037
Entamoeba histolytica recQ family helicase, putative Get druggable targets OG5_126644 All targets in OG5_126644
Toxoplasma gondii endonuclease IV APN Get druggable targets OG5_129467 All targets in OG5_129467
Leishmania braziliensis mitogen activated protein kinase, putative,map kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Neospora caninum hypothetical protein Get druggable targets OG5_126810 All targets in OG5_126810
Trichomonas vaginalis DNA helicase recq1, putative Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 Get druggable targets OG5_129037 All targets in OG5_129037
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132352 All targets in OG5_132352
Trypanosoma brucei mitogen activated protein kinase 4, putative Get druggable targets OG5_126781 All targets in OG5_126781
Cryptosporidium parvum MAPK, putative Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum expressed protein Get druggable targets OG5_127901 All targets in OG5_127901
Leishmania braziliensis isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus granulosus mitogen activated protein kinase 3 Get druggable targets OG5_126781 All targets in OG5_126781
Candida albicans similar to S. cerevisiae RAD52 (YML032C) dsDNA break repair annealing factor Get druggable targets OG5_130806 All targets in OG5_130806
Leishmania major apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania donovani apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis flap endonuclease-1, putative Get druggable targets OG5_127472 All targets in OG5_127472
Trypanosoma brucei gambiense mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Brugia malayi Pax transcription factor protein 2 Get druggable targets OG5_139945 All targets in OG5_139945
Trypanosoma cruzi mitogen-activated protein kinase 11, putative Get druggable targets OG5_126781 All targets in OG5_126781
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_136365 All targets in OG5_136365
Plasmodium yoelii peroxisomal-coenzyme a synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania mexicana apurinic/apyrimidinic endonuclease-redox protein,AP-endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus bromodomain adjacent to zinc finger domain Get druggable targets OG5_131570 All targets in OG5_131570
Plasmodium berghei isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania braziliensis serine/threonine-protein kinase, putative,protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Echinococcus multilocularis jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Trypanosoma brucei isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Schistosoma japonicum Mitogen-activated protein kinase 3, putative Get druggable targets OG5_126781 All targets in OG5_126781
Brugia malayi Protein kinase domain containing protein Get druggable targets OG5_134863 All targets in OG5_134863
Echinococcus granulosus Basic leucine zipper bZIP transcription factor Get druggable targets OG5_131442 All targets in OG5_131442
Mycobacterium ulcerans DNA polymerase IV Get druggable targets OG5_127393 All targets in OG5_127393
Schistosoma japonicum Bloom syndrome protein homolog, putative Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania mexicana phosphatidylinositol 3 kinase, putative Get druggable targets OG5_127212 All targets in OG5_127212
Echinococcus multilocularis ATP dependent DNA helicase Q1 Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus multilocularis lamin Get druggable targets OG5_128723 All targets in OG5_128723
Candida albicans similar to N terminal region of S. cerevisiae TOR2 (YKL203C) and TOR1 (YJR066W) putative protein/phosphatidylinositol kinases in Get druggable targets OG5_127212 All targets in OG5_127212
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Leishmania braziliensis mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Brugia malayi Intermediate filament tail domain containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania mexicana tyrosyl-DNA phosphodiesterase-like protein Get druggable targets OG5_129037 All targets in OG5_129037
Leishmania braziliensis DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Cryptosporidium parvum DinB/family X-type DNA polymerase Get druggable targets OG5_128521 All targets in OG5_128521
Echinococcus multilocularis inositol monophosphatase 1 Get druggable targets OG5_126810 All targets in OG5_126810
Plasmodium berghei AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania donovani DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Schistosoma mansoni inositol monophosphatase Get druggable targets OG5_126810 All targets in OG5_126810
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Schistosoma japonicum ko:K09188 myeloid/lymphoid or mixed-lineage leukemia protein 3, putative Get druggable targets OG5_130642 All targets in OG5_130642
Echinococcus granulosus bloom syndrome protein Get druggable targets OG5_126644 All targets in OG5_126644
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Schistosoma mansoni hypothetical protein Get druggable targets OG5_133913 All targets in OG5_133913
Candida albicans Mitochondrial NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Cryptosporidium hominis dna-(apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei gambiense DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Toxoplasma gondii ImpB/MucB/SamB family protein Get druggable targets OG5_128521 All targets in OG5_128521
Mycobacterium ulcerans serine/threonine-protein kinase B PknB Get druggable targets OG5_146588 All targets in OG5_146588
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Trichomonas vaginalis chromobox protein, putative Get druggable targets OG5_129545 All targets in OG5_129545
Plasmodium vivax flap endonuclease 1, putative Get druggable targets OG5_127472 All targets in OG5_127472
Schistosoma mansoni lipoxygenase Get druggable targets OG5_127482 All targets in OG5_127482
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_136365 All targets in OG5_136365
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis mitogen activated protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_127212 All targets in OG5_127212
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Loa Loa (eye worm) CAMK/PIM protein kinase Get druggable targets OG5_134863 All targets in OG5_134863
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) Get druggable targets OG5_127393 All targets in OG5_127393
Echinococcus granulosus transcription factor Dp 1 Get druggable targets OG5_129037 All targets in OG5_129037
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania infantum mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Leishmania donovani mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Plasmodium berghei flap endonuclease 1, putative Get druggable targets OG5_127472 All targets in OG5_127472
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative Get druggable targets OG5_129467 All targets in OG5_129467
Candida albicans similar to S. cerevisiae DNA polymerase pol-eta, involved in the bypass of distorted DNA lesions Get druggable targets OG5_128521 All targets in OG5_128521
Candida albicans similar to S. cerevisiae DNA polymerase pol-eta, involved in the bypass of distorted DNA lesions Get druggable targets OG5_128521 All targets in OG5_128521
Mycobacterium ulcerans extragenic suppressor protein SuhB Get druggable targets OG5_126810 All targets in OG5_126810
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus granulosus microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Trypanosoma congolense serine/threonine-protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Cryptosporidium parvum conserved hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Babesia bovis ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative Get druggable targets OG5_127212 All targets in OG5_127212
Schistosoma japonicum JmjC domain-containing histone demethylation protein 3C, putative Get druggable targets OG5_127917 All targets in OG5_127917
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum ko:K07203 FKBP12-rapamycin complex-associated protein, putative Get druggable targets OG5_127212 All targets in OG5_127212
Entamoeba histolytica exodeoxyribonuclease III, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K04380 microtubule-associated protein tau, putative Get druggable targets OG5_133504 All targets in OG5_133504
Echinococcus granulosus proto oncogene serine:threonine protein kinase Get druggable targets OG5_134863 All targets in OG5_134863
Onchocerca volvulus Get druggable targets OG5_131470 All targets in OG5_131470
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Neospora caninum endonuclease V, putative Get druggable targets OG5_129467 All targets in OG5_129467
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Entamoeba histolytica myo-inositol monophosphatase, putative Get druggable targets OG5_126810 All targets in OG5_126810
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126644 All targets in OG5_126644
Cryptosporidium parvum AP endonuclease of the TIM barrel fold, possible bacterial horizontal transfer Get druggable targets OG5_129467 All targets in OG5_129467
Candida albicans MAP kinase-like orf Get druggable targets OG5_126781 All targets in OG5_126781
Cryptosporidium parvum tyrosyl-DNA phodphodiesterase 1 (tdp1) Get druggable targets OG5_129037 All targets in OG5_129037
Leishmania mexicana myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative Get druggable targets OG5_146588 All targets in OG5_146588
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor Get druggable targets OG5_131442 All targets in OG5_131442
Trichomonas vaginalis chromobox protein, putative Get druggable targets OG5_129545 All targets in OG5_129545
Plasmodium berghei acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani Phosphatidylinositol 3-kinase tor1 Get druggable targets OG5_127212 All targets in OG5_127212
Toxoplasma gondii isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Echinococcus multilocularis flap endonuclease 1 Get druggable targets OG5_127472 All targets in OG5_127472
Plasmodium yoelii isocitrate dehydrogenase, NADP-dependent Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma cruzi CMGC/DYRK protein kinase, putative Get druggable targets OG5_127901 All targets in OG5_127901
Plasmodium knowlesi AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative Get druggable targets OG5_127472 All targets in OG5_127472
Echinococcus granulosus lamin Get druggable targets OG5_128723 All targets in OG5_128723
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Giardia lamblia Kinase, CMGC MAPK Get druggable targets OG5_126781 All targets in OG5_126781
Brugia malayi exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Cryptosporidium hominis DEAD/DEAH box helicase Get druggable targets OG5_126644 All targets in OG5_126644
Giardia lamblia Flap structure-specific endonuclease Get druggable targets OG5_127472 All targets in OG5_127472
Brugia malayi Protein kinase domain containing protein Get druggable targets OG5_127901 All targets in OG5_127901
Plasmodium yoelii putative 3-methyladenine DNA glycosylase Get druggable targets OG5_130143 All targets in OG5_130143
Brugia malayi MH2 domain containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Trypanosoma congolense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Cryptosporidium hominis apurinic/apyrimidinic endonuclease Apn1 Get druggable targets OG5_129467 All targets in OG5_129467
Echinococcus multilocularis musashi Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum Serine/threonine-protein kinase minibrain, putative Get druggable targets OG5_127901 All targets in OG5_127901
Schistosoma japonicum ko:K01549 ATP synthase [EC3.6.3.14], putative Get druggable targets OG5_131570 All targets in OG5_131570
Echinococcus multilocularis tumor protein p63 Get druggable targets OG5_140038 All targets in OG5_140038
Brugia malayi Serine/threonine-protein kinase Pim-3 Get druggable targets OG5_134863 All targets in OG5_134863
Leishmania infantum tyrosyl-DNA phosphodiesterase 1 Get druggable targets OG5_129037 All targets in OG5_129037
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Trichomonas vaginalis DNA polymerase IV / kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Onchocerca volvulus Get druggable targets OG5_136365 All targets in OG5_136365
Babesia bovis apurinic endonuclease (APN1) family protein Get druggable targets OG5_129467 All targets in OG5_129467
Echinococcus granulosus jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Leishmania braziliensis DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133916 All targets in OG5_133916
Leishmania infantum mitogen activated protein kinase, putative,map kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein Get druggable targets OG5_126644 All targets in OG5_126644
Leishmania infantum myo-inositol-1(or 4)-monophosphatase 1, putative Get druggable targets OG5_126810 All targets in OG5_126810
Trypanosoma cruzi DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core Get druggable targets OG5_139225 All targets in OG5_139225
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative Get druggable targets OG5_146588 All targets in OG5_146588
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132551 All targets in OG5_132551
Entamoeba histolytica Flap nuclease, putative Get druggable targets OG5_127472 All targets in OG5_127472
Loa Loa (eye worm) RecQ helicase Get druggable targets OG5_126644 All targets in OG5_126644
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Leishmania infantum target of rapamycin (TOR) kinase 2, putative Get druggable targets OG5_127212 All targets in OG5_127212
Trypanosoma brucei DNA polymerase IV, putative Get druggable targets OG5_127393 All targets in OG5_127393
Trypanosoma brucei DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium vivax acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum ko:K03509 DNA polymerase eta subunit, putative Get druggable targets OG5_128521 All targets in OG5_128521
Brugia malayi RhoGAP domain containing protein Get druggable targets OG5_132551 All targets in OG5_132551
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative Get druggable targets OG5_127212 All targets in OG5_127212
Echinococcus granulosus Rac GTPase activating protein 1 Get druggable targets OG5_132551 All targets in OG5_132551
Echinococcus granulosus chromobox protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Chlamydia trachomatis endonuclease IV Get druggable targets OG5_129467 All targets in OG5_129467
Neospora caninum Phosphatidylinositol 3-kinase tor2, related Get druggable targets OG5_127212 All targets in OG5_127212
Mycobacterium ulcerans long-chain fatty-acid CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei gambiense DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Plasmodium yoelii isocitrate dehydrogenase, NADP-dependent, putative Get druggable targets OG5_127057 All targets in OG5_127057
Trichomonas vaginalis conserved hypothetical protein Get druggable targets OG5_130143 All targets in OG5_130143
Echinococcus granulosus dna polymerase eta Get druggable targets OG5_128521 All targets in OG5_128521
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Brugia malayi hypothetical protein Get druggable targets OG5_132873 All targets in OG5_132873
Schistosoma japonicum ko:K03654 ATP-dependent DNA helicase RecQ, putative Get druggable targets OG5_126644 All targets in OG5_126644
Echinococcus granulosus ATP dependent DNA helicase Q5 Get druggable targets OG5_126644 All targets in OG5_126644
Toxoplasma gondii exonuclease III APE Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei gambiense DNA polymerase kappa, putative Get druggable targets OG5_127393 All targets in OG5_127393
Neospora caninum flap endonuclease-1, putative Get druggable targets OG5_127472 All targets in OG5_127472
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum ko:K07611 lamin, putative Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum IPR001024,Lipoxygenase, LH2;IPR013819,Lipoxygenase, C-terminal,domain-containing Get druggable targets OG5_127482 All targets in OG5_127482
Entamoeba histolytica DNA repair and recombination protein RAD52, putative Get druggable targets OG5_130806 All targets in OG5_130806
Leishmania major DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Leishmania donovani isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Dictyostelium discoideum 3',5'-bisphosphate nucleotidase 1 Inositol monophosphatase 1   277 aa 275 aa 22.2 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 505 aa 28.1 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferase   552 aa 491 aa 23.2 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 452 aa 26.1 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD23 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 542 aa 23.8 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 494 aa 24.3 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 524 aa 24.0 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 537 aa 20.9 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD11 Luciferin 4-monooxygenase   550 aa 498 aa 23.5 %
Brugia malayi Hypothetical 65.5 kDa Trp-Asp repeats containing protein F02E8.5 inchromosome X geminin, DNA replication inhibitor 209 aa 176 aa 27.8 %
Leishmania infantum long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Leishmania mexicana long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 483 aa 23.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Trypanosoma congolense inositol-1(or 4)-monophosphatase, putative Inositol monophosphatase 1   277 aa 304 aa 28.9 %
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase Luciferin 4-monooxygenase   550 aa 536 aa 24.4 %
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 509 aa 21.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 463 aa 23.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 497 aa 24.7 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 507 aa 20.9 %
Toxoplasma gondii type I fatty acid synthase, putative Luciferin 4-monooxygenase   550 aa 514 aa 19.8 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 517 aa 24.8 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 581 aa 21.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 461 aa 22.3 %
Schistosoma japonicum Ferritin, putative Ferritin light chain   175 aa 144 aa 24.3 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 593 aa 22.1 %
Onchocerca volvulus Putative trans-2-enoyl-CoA reductase 1, mitochondrial Inositol monophosphatase 1   277 aa 278 aa 23.0 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba Putative fructose-1,6-bisphosphate aldolase   323 aa 361 aa 25.5 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 24.4 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 603 aa 22.6 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.5 %
Trypanosoma brucei exonuclease, putative flap structure-specific endonuclease 1 380 aa 322 aa 24.5 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Mycobacterium tuberculosis Hypothetical protein Nonstructural protein 1   230 aa 202 aa 23.8 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 490 aa 23.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 558 aa 20.4 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 480 aa 22.5 %
Giardia lamblia Long chain fatty acid CoA ligase 5 Luciferase   552 aa 491 aa 21.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Brugia malayi MH2 domain containing protein SMAD family member 2 467 aa 405 aa 31.6 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Trypanosoma brucei gambiense inositol-1(or 4)-monophosphatase, putative Inositol monophosphatase 1   277 aa 309 aa 27.8 %
Trichomonas vaginalis AMP dependent ligase, putative Luciferin 4-monooxygenase   550 aa 445 aa 26.1 %
Echinococcus granulosus long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Loa Loa (eye worm) AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 489 aa 23.3 %
Cryptosporidium parvum acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 25.7 %
Schistosoma mansoni pap-inositol-14-phosphatase Inositol monophosphatase 1   277 aa 279 aa 22.9 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 577 aa 22.2 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 Luciferin 4-monooxygenase   550 aa 463 aa 21.8 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD28 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 504 aa 22.6 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 476 aa 23.5 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 497 aa 19.3 %
Babesia bovis long-chain acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 445 aa 21.8 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 526 aa 22.4 %
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba Putative fructose-1,6-bisphosphate aldolase   323 aa 361 aa 25.8 %
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 535 aa 23.2 %
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative Inositol monophosphatase 1   277 aa 287 aa 22.3 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 22.9 %
Cryptosporidium parvum putative long chain fatty acyl CoA synthetase having a signal peptide Luciferin 4-monooxygenase   550 aa 472 aa 24.8 %
Theileria parva long-chain fatty acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 507 aa 23.5 %
Mycobacterium tuberculosis Probable acyl-CoA ligase FadD31 (acyl-CoA synthetase) (acyl-CoA synthase) Luciferin 4-monooxygenase   550 aa 592 aa 20.4 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD28 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 484 aa 20.5 %
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative Luciferase   552 aa 544 aa 21.7 %
Trypanosoma cruzi inositol polyphosphate 1-phosphatase, putative Inositol monophosphatase 1   277 aa 291 aa 23.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 21.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Giardia lamblia U5 small nuclear ribonucleoprotein 200 kDa helicase, putative RecQ helicase-like 649 aa 521 aa 19.8 %
Echinococcus multilocularis long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE Luciferin 4-monooxygenase   550 aa 502 aa 22.5 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD32 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase). Also shown to have acyl-ACP ligase activity. Luciferin 4-monooxygenase   550 aa 487 aa 22.4 %
Trypanosoma brucei inositol-1(or 4)-monophosphatase, putative Inositol monophosphatase 1   277 aa 304 aa 27.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 499 aa 19.2 %
Mycobacterium ulcerans non-ribosomal peptide synthetase Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Schistosoma mansoni apoferritin-2 Ferritin light chain   175 aa 142 aa 29.6 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferase   552 aa 451 aa 22.4 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 5 Luciferase   552 aa 481 aa 25.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 495 aa 22.6 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 24.7 %
Mycobacterium ulcerans fructose-bisphosphate aldolase Putative fructose-1,6-bisphosphate aldolase   323 aa 361 aa 26.9 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 482 aa 24.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Onchocerca volvulus Putative 28S ribosomal protein S10, mitochondrial Inositol monophosphatase 1   277 aa 271 aa 46.1 %
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Toxoplasma gondii propionate-CoA ligase Luciferin 4-monooxygenase   550 aa 550 aa 21.1 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 582 aa 22.3 %
Mycobacterium ulcerans putative fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 576 aa 20.8 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 459 aa 27.0 %
Candida albicans fructose-bisphosphate aldolase Putative fructose-1,6-bisphosphate aldolase   323 aa 358 aa 22.6 %
Trichomonas vaginalis myo inositol monophosphatase, putative Inositol monophosphatase 1   277 aa 276 aa 21.4 %
Trichomonas vaginalis inositol monophosphatase, putative Inositol monophosphatase 1   277 aa 258 aa 21.7 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 5 Luciferase   552 aa 470 aa 25.1 %
Dictyostelium discoideum 3',5'-bisphosphate nucleotidase Inositol monophosphatase 1   277 aa 230 aa 25.2 %
Leishmania braziliensis long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 496 aa 22.8 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 596 aa 21.1 %
Candida albicans one of two closely related genes similar to S. cerevisiae MET22/HAL2 (YOL064C) bisphosphate-3'-nucleotidase, implicated in salt Inositol monophosphatase 1   277 aa 307 aa 22.5 %
Brugia malayi AMP-binding enzyme family protein Luciferase   552 aa 492 aa 24.8 %
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative polymerase (DNA directed), beta 335 aa 303 aa 32.3 %
Schistosoma mansoni long-chain-fatty-acid--CoA ligase Luciferase   552 aa 526 aa 22.2 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD26 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 560 aa 21.4 %
Neospora caninum hypothetical protein Luciferase   552 aa 529 aa 22.5 %
Babesia bovis fatty acyl-CoA synthetase family protein Luciferin 4-monooxygenase   550 aa 461 aa 23.4 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD21 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 586 aa 24.4 %
Brugia malayi steroid hormone receptor vitamin D (1,25- dihydroxyvitamin D3) receptor 427 aa 416 aa 24.5 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.8 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 1 Luciferase   552 aa 481 aa 23.7 %
Schistosoma mansoni ferritin Ferritin light chain   175 aa 171 aa 43.9 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 493 aa 20.7 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 501 aa 24.4 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 487 aa 23.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 22.6 %
Onchocerca volvulus Inositol monophosphatase 1   277 aa 238 aa 22.7 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 601 aa 22.5 %
Loa Loa (eye worm) hypothetical protein Inositol monophosphatase 1   277 aa 298 aa 23.8 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 462 aa 23.8 %
Mycobacterium leprae FATTY-ACID-CoA LIGASE FADD26 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 533 aa 22.7 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 530 aa 23.8 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD24 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 526 aa 21.9 %
Onchocerca volvulus Lysine-specific histone demethylase 1A homolog Luciferin 4-monooxygenase   550 aa 550 aa 22.5 %
Theileria parva acetyl-coenzyme A synthetase, putative Luciferase   552 aa 580 aa 22.4 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 527 aa 25.0 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase, FadD11 Luciferin 4-monooxygenase   550 aa 492 aa 24.6 %
Cryptosporidium hominis acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 26.1 %
Candida albicans similar to S. cerevisiae FAA4 (YMR246W) long-chain fatty acid--CoA synthetase Luciferin 4-monooxygenase   550 aa 478 aa 23.4 %
Candida albicans fructose-bisphosphate aldolase Putative fructose-1,6-bisphosphate aldolase   323 aa 358 aa 22.6 %
Trypanosoma brucei fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) Luciferase   552 aa 512 aa 22.7 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 4, putative Luciferin 4-monooxygenase   550 aa 497 aa 23.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 476 aa 20.8 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD25 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 475 aa 21.1 %
Neospora caninum Short-chain dehydrogenase/reductase SDR, related Luciferin 4-monooxygenase   550 aa 518 aa 19.1 %
Trichomonas vaginalis diphosphonucleoside phosphohydrolase, putative Inositol monophosphatase 1   277 aa 263 aa 21.7 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 492 aa 23.6 %
Echinococcus granulosus expressed protein Ferritin light chain   175 aa 146 aa 28.8 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 480 aa 25.2 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 544 aa 21.5 %
Leishmania braziliensis long-chain-fatty-acid-CoA ligase, putative Luciferase   552 aa 476 aa 25.4 %
Schistosoma mansoni ferritin Ferritin light chain   175 aa 171 aa 44.4 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD32 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 442 aa 23.5 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 443 aa 26.4 %
Leishmania mexicana long-chain-fatty-acid-CoA ligase, putative,acyl-CoA synthetase, putative,fatty acid thiokinase (long chain), putative Luciferase   552 aa 472 aa 21.6 %
Trypanosoma cruzi myo-inositol-1 phosphatase, putative Inositol monophosphatase 1   277 aa 284 aa 30.6 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Brugia malayi ecdysteroid receptor peroxisome proliferator-activated receptor delta 441 aa 369 aa 24.7 %
Neospora caninum acetyl-coenzyme a synthetase, putative Luciferin 4-monooxygenase   550 aa 549 aa 20.9 %
Entamoeba histolytica acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 446 aa 22.0 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 531 aa 19.0 %
Mycobacterium leprae Probable long-chain-fatty-acid-CoA ligase FadD15 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 484 aa 23.3 %
Leishmania major long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 23.2 %
Brugia malayi Inositol monophosphatase family protein Inositol monophosphatase 1   277 aa 238 aa 21.8 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 466 aa 27.3 %
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein Luciferin 4-monooxygenase   550 aa 476 aa 22.5 %
Trichomonas vaginalis inositol monophosphatase, putative Inositol monophosphatase 1   277 aa 268 aa 22.4 %
Echinococcus multilocularis expressed protein Ferritin light chain   175 aa 146 aa 30.1 %
Cryptosporidium hominis acetyl-CoenzymeA synthetase (acetate--coa ligase) (acyl-activating enzyme) Luciferin 4-monooxygenase   550 aa 549 aa 22.6 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 466 aa 21.7 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 484 aa 26.0 %
Schistosoma mansoni apoferritin-2 Ferritin light chain   175 aa 146 aa 28.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 576 aa 19.8 %
Trypanosoma congolense fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 500 aa 22.4 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 545 aa 24.9 %
Leishmania donovani long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Trypanosoma brucei mitogen-activated protein kinase 5 mitogen-activated protein kinase 1 360 aa 361 aa 33.2 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 550 aa 20.9 %
Schistosoma japonicum ko:K01082 3'(2'), 5'-bisphosphate nucleotidase [EC3.1.3.7], putative Inositol monophosphatase 1   277 aa 275 aa 21.5 %
Onchocerca volvulus Matrilysin homolog Luciferin 4-monooxygenase   550 aa 466 aa 24.2 %
Onchocerca volvulus Luciferase   552 aa 553 aa 24.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 478 aa 21.1 %
Mycobacterium leprae PROBABLE FATTY-ACID--CoA LIGASE FADD21 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 565 aa 22.8 %
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 Luciferin 4-monooxygenase   550 aa 493 aa 22.1 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 502 aa 24.9 %
Candida albicans one of two closely related genes similar to S. cerevisiae MET22/HAL2 (YOL064C) bisphosphate-3'-nucleotidase, implicated in salt Inositol monophosphatase 1   277 aa 300 aa 22.0 %
Dictyostelium discoideum acetyl-CoA ligase Luciferin 4-monooxygenase   550 aa 549 aa 22.2 %
Leishmania braziliensis long-chain-fatty-acid-CoA ligase, putative Luciferin 4-monooxygenase   550 aa 504 aa 25.6 %
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 509 aa 22.6 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF Luciferin 4-monooxygenase   550 aa 558 aa 20.1 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD29 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 617 aa 22.2 %
Candida albicans one of two closely related genes similar to S. cerevisiae MET22/HAL2 (YOL064C) bisphosphate-3'-nucleotidase, implicated in salt Inositol monophosphatase 1   277 aa 306 aa 22.5 %
Theileria parva long-chain fatty acid CoA ligase, putative Luciferase   552 aa 468 aa 20.5 %
Schistosoma japonicum ko:K08745 solute carrier family 27 (fatty acid transporter), member 1, putative Luciferin 4-monooxygenase   550 aa 501 aa 24.6 %
Mycobacterium tuberculosis Long-chain-fatty-acid-CoA ligase FadD15 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferase   552 aa 483 aa 23.6 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 494 aa 23.9 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Babesia bovis acetyl-CoA synthetase, putative Luciferase   552 aa 545 aa 21.3 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD29 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 529 aa 22.3 %
Leishmania mexicana acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 559 aa 20.6 %
Plasmodium vivax long-chain fatty acid CoA ligase, putative Luciferase   552 aa 453 aa 24.5 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD6 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferase   552 aa 481 aa 20.4 %
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative Inositol monophosphatase 1   277 aa 263 aa 24.0 %
Schistosoma mansoni FAA1 Long-chain-fatty-acid--CoA ligase 1 Luciferin 4-monooxygenase   550 aa 494 aa 26.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 480 aa 21.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Entamoeba histolytica acyl-CoA synthetase, putative Luciferase   552 aa 510 aa 23.1 %
Cryptosporidium parvum acetyl-coenzyme A synthetase Luciferin 4-monooxygenase   550 aa 545 aa 22.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0053 0.023 0.0667
Plasmodium vivax ataxin-2 like protein, putative 0.003 0.0076 0.0459
Onchocerca volvulus 0.0058 0.0262 0.0676
Mycobacterium tuberculosis Probable bifunctional membrane-associated penicillin-binding protein 1A/1B PonA2 (murein polymerase) [includes: penicillin-insen 0.0513 0.3303 0.3859
Brugia malayi tailless protein 0.0031 0.0082 0.0237
Brugia malayi MAP kinase sur-1 0.0063 0.0296 0.0859
Treponema pallidum ATP-dependent DNA helicase 0.0024 0.0031 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0116 0.0415
Trichomonas vaginalis maltase-glucoamylase, putative 0.004 0.0143 0.0539
Mycobacterium leprae PROBABLE BIFUNCTIONAL MEMBRANE-ASSOCIATED PENICILLIN-BINDING PROTEIN 1A/1B PONA2 (MUREIN POLYMERASE) [INCLUDES: PENICILLIN-INSEN 0.0513 0.3303 0.3837
Brugia malayi Intermediate filament tail domain containing protein 0.0033 0.009 0.0261
Loa Loa (eye worm) hypothetical protein 0.0035 0.0108 0.0313
Entamoeba histolytica hypothetical protein 0.011 0.0606 0.2189
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0043 0.0163 0.0163
Loa Loa (eye worm) TAR-binding protein 0.0071 0.0347 0.1006
Schistosoma mansoni nuclear receptor 0.0031 0.0082 0.0082
Schistosoma mansoni DNA helicase recq5 0.0047 0.0184 0.0184
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0066 0.0316 0.0917
Schistosoma mansoni lamin 0.0033 0.009 0.009
Schistosoma mansoni survival motor neuron protein 0.0058 0.0262 0.0262
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0082 0.0082
Plasmodium vivax DNA-3-methyladenine glycosylase, putative 0.0266 0.1655 1
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0029 0.0068 0.0068
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0035 0.0109 0.0384
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0057 0.0256 0.0256
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0049 0.0202 0.1219
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0066 0.0316 0.0917
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0031 0.0089
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0028 0.0057 0.0057
Brugia malayi MH2 domain containing protein 0.0262 0.1624 0.4707
Echinococcus granulosus dna polymerase kappa 0.0096 0.0516 0.0516
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0066 0.0316 0.0835
Entamoeba histolytica protein kinase, putative 0.011 0.0606 0.2189
Echinococcus granulosus histone lysine methyltransferase setb 0.0057 0.0256 0.0256
Schistosoma mansoni hypothetical protein 0.0058 0.0262 0.0262
Brugia malayi TAR-binding protein 0.0071 0.0347 0.1006
Brugia malayi Protein kinase domain containing protein 0.011 0.0606 0.1756
Echinococcus granulosus geminin 0.0368 0.2334 0.2334
Brugia malayi hypothetical protein 0.0136 0.0783 0.2268
Onchocerca volvulus 0.0081 0.0412 0.1114
Mycobacterium ulcerans epimerase 0.0024 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0066 0.0316 0.0917
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0032 0.0085 0.0085
Echinococcus granulosus tumor protein p63 0.0408 0.2602 0.2602
Schistosoma mansoni hypothetical protein 0.0025 0.0039 0.0039
Entamoeba histolytica protein kinase domain containing protein 0.011 0.0606 0.2189
Schistosoma mansoni cpg binding protein 0.0039 0.0133 0.0133
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.004 0.014 0.0164
Schistosoma mansoni tar DNA-binding protein 0.0071 0.0347 0.0347
Trichomonas vaginalis sucrase-isomaltase, putative 0.004 0.0143 0.0539
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0057 0.0256 0.0256
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0024 0.0031 0.0036
Trypanosoma brucei hypothetical protein, conserved 0.002 0.0005 0.0023
Loa Loa (eye worm) hypothetical protein 0.006 0.0275 0.0798
Brugia malayi latrophilin 2 splice variant baaae 0.0074 0.0369 0.107
Loa Loa (eye worm) intermediate filament protein 0.0033 0.009 0.0261
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0023 0.0025 0.0151
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0093 0.0492 0.054
Mycobacterium leprae conserved hypothetical protein 0.004 0.014 0.0128
Echinococcus multilocularis chromobox protein 2 0.0028 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0081 0.0412 0.1193
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0031 0.0083 0.0161
Plasmodium falciparum acyl-CoA synthetase 0.006 0.0275 0.1665
Echinococcus granulosus mitogen activated protein kinase 3 0.0063 0.0296 0.0296
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0034 0.0102 0.0102
Entamoeba histolytica acyl-CoA synthetase, putative 0.0081 0.0412 0.1459
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0031 0.0632
Brugia malayi PHD-finger family protein 0.0032 0.0087 0.0252
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0066 0.0316 0.0316
Brugia malayi beta-lactamase family protein 0.004 0.014 0.0406
Entamoeba histolytica recQ family helicase, putative 0.0023 0.0025 0.0003
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0063 0.0296 0.603
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0365 0.2313 1
Onchocerca volvulus Bile acid receptor homolog 0.0066 0.0316 0.0835
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0032 0.0085 0.0274
Trichomonas vaginalis DNA helicase recq, putative 0.0079 0.0399 0.1695
Entamoeba histolytica recQ family helicase, putative 0.0053 0.0228 0.0767
Echinococcus granulosus FTZ F1 alpha 0.0066 0.0316 0.0316
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0172 0.1026 0.1167
Trichomonas vaginalis chromobox protein, putative 0.0028 0.0057 0.0146
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0034 0.0102 0.0102
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.004 0.0139 0.0128
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0054 0.0235 0.0459
Schistosoma mansoni hypothetical protein 0.0034 0.0102 0.0102
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.0516 0.2231
Trypanosoma brucei DNA polymerase IV, putative 0.0096 0.0516 0.2231
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0054 0.0235 0.0795
Echinococcus multilocularis flap endonuclease 1 0.0031 0.0083 0.0083
Echinococcus multilocularis bloom syndrome protein 0.0079 0.0399 0.0399
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0071 0.0347 0.1006
Onchocerca volvulus Alhambra homolog 0.0035 0.0108 0.0226
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0057 0.0253 0.0296
Echinococcus granulosus PHD finger protein rhinoceros 0.0035 0.0108 0.0108
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0024 0.0031 0.0133
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0063 0.0296 0.0578
Echinococcus multilocularis tumor protein p63 0.0408 0.2602 0.2602
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0023 0.0024 0.0105
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0143 0.0539
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0047 0.0184 0.0532
Toxoplasma gondii target of rapamycin (TOR), putative 0.004 0.0142 0.2897
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.014 0.0525
Echinococcus granulosus intermediate filament protein 0.0033 0.009 0.009
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.008 0.0406 0.1176
Giardia lamblia PHD finger protein 15 0.0035 0.0108 0.0383
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0786 0.5129 1
Echinococcus multilocularis survival motor neuron protein 1 0.0286 0.1783 0.1783
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0282 0.0323
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0066 0.0316 0.0917
Brugia malayi nuclear receptor RXR 0.0035 0.0107 0.031
Loa Loa (eye worm) hypothetical protein 0.0047 0.0184 0.0532
Trypanosoma brucei hypothetical protein, conserved 0.004 0.014 0.0606
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0028 0.0057 0.0122
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0028 0.0057 0.1152
Loa Loa (eye worm) hypothetical protein 0.0035 0.0107 0.031
Brugia malayi Pax transcription factor protein 2 0.0291 0.1817 0.5265
Echinococcus multilocularis GPCR, family 2 0.0034 0.0102 0.0102
Echinococcus multilocularis ecdysone induced protein 78C 0.0066 0.0316 0.0316
Echinococcus granulosus Nuclear hormone receptor HR96 0.0031 0.0082 0.0082
Brugia malayi hypothetical protein 0.0035 0.0107 0.031
Onchocerca volvulus 0.004 0.014 0.032
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.014 0.0525
Schistosoma mansoni hypothetical protein 0.0028 0.0057 0.0057
Echinococcus granulosus jun protein 0.0101 0.0551 0.0551
Schistosoma mansoni jumonji/arid domain-containing protein 0.0047 0.0186 0.0186
Echinococcus multilocularis lysine specific demethylase 5A 0.0043 0.0157 0.0157
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.0516 0.2231
Treponema pallidum penicillin-binding protein (pbp-3) 0.0513 0.3303 1
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0054 0.0235 0.0235
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0063 0.0296 0.1282
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0171 0.0333
Trichomonas vaginalis DNA helicase recq, putative 0.0053 0.0228 0.0923
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0054 0.0235 0.0235
Mycobacterium ulcerans acetyl-CoA synthetase 0.0024 0.0031 0.003
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0066 0.0316 0.0316
Loa Loa (eye worm) hypothetical protein 0.0136 0.0783 0.2268
Loa Loa (eye worm) hypothetical protein 0.0028 0.0057 0.0164
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.2234 1
Onchocerca volvulus 0.0031 0.0082 0.0149
Loa Loa (eye worm) hypothetical protein 0.0031 0.0082 0.0237
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.011 0.0606 0.1181
Leishmania major alpha glucosidase II subunit, putative 0.004 0.0143 0.062
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0143 0.0279
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0066 0.0316 0.0316
Toxoplasma gondii exonuclease III APE 0.0023 0.0024 0.0494
Echinococcus granulosus beta LACTamase domain containing family member 0.004 0.014 0.014
Trichomonas vaginalis chromobox protein, putative 0.0098 0.0527 0.2277
Loa Loa (eye worm) PHD-finger family protein 0.0035 0.0108 0.0313
Echinococcus multilocularis PHD finger protein rhinoceros 0.0035 0.0108 0.0108
Schistosoma mansoni inositol monophosphatase 0.0045 0.0171 0.0171
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0031 0.0082 0.0149
Onchocerca volvulus 0.004 0.014 0.032
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0028 0.0057 0.0057
Schistosoma mansoni RAR-like nuclear receptor 0.0066 0.0316 0.0316
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0066 0.0311 0.0311
Entamoeba histolytica deoxycytidyl transferase, putative 0.0064 0.0301 0.1042
Mycobacterium ulcerans acyl-CoA synthetase 0.0081 0.0412 0.0475
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0109 0.0598 0.0598
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0143 0.0539
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0173 0.1027 0.2003
Loa Loa (eye worm) hypothetical protein 0.0035 0.0107 0.031
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0023 0.0024 0.0022
Brugia malayi Steroid receptor seven-up type 2 0.0066 0.0316 0.0917
Loa Loa (eye worm) oxidoreductase 0.0024 0.0031 0.0089
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0068 0.0198
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0066 0.0316 0.0316
Mycobacterium tuberculosis Conserved protein 0.004 0.014 0.0164
Schistosoma mansoni tar DNA-binding protein 0.0071 0.0347 0.0347
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0043 0.0161 0.0698
Brugia malayi nuclear hormone receptor 0.0066 0.0316 0.0917
Echinococcus multilocularis lamin 0.0033 0.009 0.009
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0035 0.0109 0.0384
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0034 0.0102 0.0297
Chlamydia trachomatis endonuclease IV 0.0093 0.0492 1
Loa Loa (eye worm) heterochromatin protein 1 0.0098 0.0527 0.1528
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0047 0.0184 0.111
Entamoeba histolytica hypothetical protein 0.0028 0.0057 0.0122
Entamoeba histolytica protein kinase, putative 0.011 0.0606 0.2189
Schistosoma mansoni hypothetical protein 0.0024 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0286 0.1783 0.5166
Echinococcus granulosus Chromobox protein 3 0.0028 0.0057 0.0057
Schistosoma mansoni blooms syndrome DNA helicase 0.0055 0.024 0.024
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.0516 0.2231
Loa Loa (eye worm) jmjC domain-containing protein 0.0073 0.0359 0.1039
Echinococcus granulosus neutral alpha glucosidase AB 0.004 0.0143 0.0143
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0031 0.0082 0.0149
Schistosoma mansoni hypothetical protein 0.0368 0.2334 0.2334
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0093 0.0492 0.2971
Loa Loa (eye worm) hypothetical protein 0.004 0.014 0.0406
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0031 0.0036
Echinococcus multilocularis dna polymerase eta 0.0095 0.0507 0.0507
Schistosoma mansoni alpha-glucosidase 0.0157 0.0923 0.0923
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0031 0.003
Loa Loa (eye worm) hypothetical protein 0.0066 0.0316 0.0917
Schistosoma mansoni hypothetical protein 0.0043 0.0163 0.0163
Onchocerca volvulus 0.0291 0.1817 0.5222
Loa Loa (eye worm) hypothetical protein 0.0028 0.0057 0.0164
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0028 0.0057 0.0057
Toxoplasma gondii PHD-finger domain-containing protein 0.0035 0.0108 0.2195
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.006 0.0275 0.0322
Schistosoma mansoni polycystin 1-related 0.0024 0.0032 0.0032
Brugia malayi hypothetical protein 0.0286 0.1783 0.5166
Schistosoma mansoni cellular tumor antigen P53 0.006 0.0272 0.0272
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0171 0.0738
Loa Loa (eye worm) hypothetical protein 0.0031 0.0082 0.0237
Giardia lamblia GTOR 0.0054 0.0235 0.086
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.004 0.0143 0.0415
Trichomonas vaginalis flap endonuclease-1, putative 0.0031 0.0083 0.0265
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0066 0.0316 0.0316
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0161 0.0619
Brugia malayi orphan nuclear receptor NR2E1 0.0031 0.0082 0.0237
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0064 0.0301 0.0301
Toxoplasma gondii ABC1 family protein 0.004 0.014 0.2852
Echinococcus multilocularis histone acetyltransferase MYST2 0.0066 0.0311 0.0311
Brugia malayi Bloom's syndrome protein homolog 0.0079 0.0399 0.1156
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0047 0.0184 0.3737
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0031 0.0082 0.0237
Loa Loa (eye worm) hypothetical protein 0.018 0.1079 0.3127
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0066 0.0316 0.0917
Brugia malayi Heterochromatin protein 1 0.0098 0.0527 0.1528
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0066 0.0316 0.0316
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0031 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0107 0.059 0.1709
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0085 0.0274
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.008 0.0406 0.0406
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0081 0.0412 0.0475
Brugia malayi hypothetical protein 0.002 0.0004 0.0011
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0031 0.003
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0173 0.1027 0.4442
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0024 0.0035 0.0035
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0066 0.0316 0.0316
Schistosoma mansoni cpg binding protein 0.0039 0.0133 0.0133
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0031 0.0089
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0072 0.0354 0.2142
Echinococcus multilocularis neuropeptide s receptor 0.0558 0.3609 0.3609
Echinococcus granulosus peregrin 0.0038 0.0127 0.0127
Echinococcus multilocularis polycomb protein SCMH1 0.0058 0.0258 0.0258
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0066 0.0316 0.0917
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0028 0.0057 0.1152
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0365 0.2313 0.4509
Echinococcus multilocularis peregrin 0.0038 0.0127 0.0127
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0066 0.0316 0.0316
Schistosoma mansoni hypothetical protein 0.0494 0.3177 0.3177
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0215 0.042
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0064 0.0301 0.0301
Schistosoma mansoni jun-related protein 0.0082 0.0424 0.0424
Schistosoma mansoni bromodomain containing protein 0.0078 0.0397 0.0397
Schistosoma mansoni chromobox protein 0.0098 0.0527 0.0527
Leishmania major DNA polymerase kappa, putative 0.0072 0.0354 0.1533
Brugia malayi Valyl-tRNA synthetase 0.0028 0.0057 0.0164
Trypanosoma cruzi target of rapamycin kinase 3 0.0043 0.0161 0.0315
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0035 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.0107 0.059 0.1709
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0089 0.0294
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0023 0.0024 0.0105
Trypanosoma brucei hypothetical protein, conserved 0.002 0.0005 0.0023
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0024 0.0031 0.003
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0109 0.0599 0.1737
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0066 0.0316 0.0917
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0035 0.0107 0.0107
Schistosoma mansoni nuclear hormone receptor 0.0066 0.0316 0.0316
Brugia malayi Latrophilin receptor protein 2 0.0034 0.0102 0.0297
Mycobacterium tuberculosis Probable conserved lipoprotein 0.004 0.014 0.0164
Mycobacterium tuberculosis Conserved hypothetical protein 0.0024 0.0035 0.0041
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0024 0.0031 0.0626
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.008 0.0406 0.0406
Schistosoma mansoni thyroid hormone receptor 0.0066 0.0316 0.0316
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0087 0.0284
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.008 0.0406 0.1754
Trypanosoma brucei unspecified product 0.0044 0.0168 0.0727
Schistosoma mansoni microtubule-associated protein tau 0.1514 1 1
Schistosoma mansoni jumonji domain containing protein 0.0092 0.0485 0.0485
Echinococcus multilocularis mitogen activated protein kinase 3 0.0063 0.0296 0.0296
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0066 0.0316 0.0917
Loa Loa (eye worm) hypothetical protein 0.004 0.014 0.0406
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0115 0.0644 0.0644
Loa Loa (eye worm) beta-lactamase 0.004 0.014 0.0406
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0142 0.0825 0.0825
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0076 0.0148
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0066 0.0316 0.0917
Brugia malayi hypothetical protein 0.0024 0.0032 0.0092
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0028 0.0057 0.0122
Schistosoma mansoni sex comb on midleg homolog 0.0058 0.0258 0.0258
Loa Loa (eye worm) hypothetical protein 0.0024 0.0032 0.0092
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0031 0.003
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0063 0.0296 0.0578
Brugia malayi Pre-SET motif family protein 0.0252 0.1559 0.4517
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0109 0.0599 0.1737
Onchocerca volvulus 0.004 0.014 0.032
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.0516 0.2231
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0053 0.0228 0.0987
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0235 0.0956
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.042 0.2681 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0023 0.0024 0.0047
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0054 0.0235 0.1018
Echinococcus multilocularis geminin 0.0368 0.2334 0.2334
Trichomonas vaginalis inositol monophosphatase, putative 0.0045 0.0171 0.0663
Echinococcus granulosus cpg binding protein 0.0039 0.0133 0.0133
Schistosoma mansoni lozenge 0.0067 0.0321 0.0321
Trichomonas vaginalis DNA polymerase eta, putative 0.0096 0.0516 0.2225
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.002 0.0009 0.001
Brugia malayi hypothetical protein 0.0024 0.0032 0.0092
Brugia malayi polk-prov protein 0.0052 0.022 0.0638
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.0516 0.2231
Trypanosoma brucei DNA polymerase kappa, putative 0.0052 0.0221 0.0957
Trypanosoma cruzi DNA polymerase kappa, putative 0.0096 0.0516 0.1006
Plasmodium vivax hypothetical protein, conserved 0.004 0.014 0.0847
Brugia malayi AMP-binding enzyme family protein 0.0081 0.0412 0.1193
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.028 0.1157
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0068 0.02
Echinococcus granulosus dual specificity 0.011 0.0606 0.0606
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0108 0.0379
Mycobacterium tuberculosis Possible 3-methyladenine DNA glycosylase Mpg 0.0266 0.1655 0.1933
Loa Loa (eye worm) hypothetical protein 0.006 0.0276 0.08
Loa Loa (eye worm) hypothetical protein 0.0179 0.1068 0.3094
Echinococcus multilocularis zinc finger protein 0.0026 0.0044 0.0044
Echinococcus multilocularis chromobox protein 1 0.0098 0.0527 0.0527
Echinococcus granulosus GPCR family 2 0.0034 0.0102 0.0102
Echinococcus multilocularis chromobox protein 1 0.0098 0.0527 0.0527
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0232 0.1422 0.1422
Loa Loa (eye worm) hypothetical protein 0.0031 0.0082 0.0237
Echinococcus granulosus neuropeptide s receptor 0.0558 0.3609 0.3609
Entamoeba histolytica Flap nuclease, putative 0.0031 0.0083 0.022
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0031 0.0036
Echinococcus multilocularis SAM and MBT domain containing protein 0.0058 0.0258 0.0258
Trichomonas vaginalis chromobox protein, putative 0.0098 0.0527 0.2277
Loa Loa (eye worm) phosphatidylinositol 3 0.0054 0.0235 0.0682
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0979 0.6424 0.6424
Echinococcus granulosus nuclear receptor nhr 48 0.0031 0.0082 0.0082
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0252 0.1559 0.4517
Brugia malayi Bromodomain containing protein 0.0093 0.0492 0.1424
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.2234 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0034 0.0102 0.0102
Echinococcus multilocularis neuropeptide receptor A26 0.0558 0.3609 0.3609
Echinococcus granulosus dna polymerase eta 0.0095 0.0507 0.0507
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0024 0.0031 0.0031
Echinococcus granulosus chromobox protein 2 0.0028 0.0057 0.0057
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0142 0.0535
Loa Loa (eye worm) hypothetical protein 0.0099 0.0532 0.1542
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0064 0.0301 0.0873
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0037 0.0119 0.0119
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0194 0.1173 0.3398
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0005 0.0011
Schistosoma mansoni thyroid hormone receptor 0.0066 0.0316 0.0316
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0051 0.0211 0.4297
Schistosoma mansoni tar DNA-binding protein 0.0071 0.0347 0.0347
Loa Loa (eye worm) hypothetical protein 0.0024 0.0032 0.0092
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0066 0.0316 0.0316
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0021 0.0016 0.0016
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0066 0.0316 0.0316
Echinococcus multilocularis thyroid hormone receptor alpha 0.0066 0.0316 0.0316
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.014 0.0525
Schistosoma mansoni DNA helicase recq1 0.0047 0.0184 0.0184
Leishmania major hypothetical protein, conserved 0.004 0.014 0.0606
Giardia lamblia Rho GAP, putative 0.0077 0.0385 0.1419
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0074 0.0368 0.0368
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0031 0.0082 0.0082
Giardia lamblia Fructose-bisphosphate aldolase 0.0353 0.2234 0.8328
Trichomonas vaginalis conserved hypothetical protein 0.0266 0.1655 0.7379
Toxoplasma gondii LsmAD domain-containing protein 0.003 0.0076 0.1546
Loa Loa (eye worm) hypothetical protein 0.0077 0.0385 0.1116
Onchocerca volvulus 0.0033 0.009 0.0174
Mycobacterium tuberculosis Conserved hypothetical protein 0.0192 0.1158 0.1352
Echinococcus multilocularis Chromo domain 0.0028 0.0057 0.0057
Leishmania major 4-coumarate:coa ligase-like protein 0.0081 0.0412 0.1781
Brugia malayi nuclear hormone receptor family member nhr-6 0.0031 0.0082 0.0237
Mycobacterium ulcerans acyl-CoA synthetase 0.0081 0.0412 0.0475
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0142 0.0535
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0066 0.0316 0.0917
Echinococcus multilocularis lysosomal alpha glucosidase 0.0182 0.1093 0.1093
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.028 0.1157
Entamoeba histolytica hypothetical protein 0.0043 0.0163 0.0522
Echinococcus granulosus Chromo domain 0.0028 0.0057 0.0057
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0068 0.02
Trichomonas vaginalis esterase, putative 0.004 0.014 0.0525
Trypanosoma brucei DNA polymerase eta, putative 0.0095 0.0507 0.2192
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0045 0.0171 0.0663
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0182 0.0715
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.004 0.0143 0.2914
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0063 0.0296 0.0578
Loa Loa (eye worm) hypothetical protein 0.0031 0.0082 0.0237
Schistosoma mansoni hypothetical protein 0.0082 0.0424 0.0424
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0035 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0066 0.0316 0.0917
Schistosoma mansoni hypothetical protein 0.0035 0.0108 0.0108
Leishmania major DNA damage repair protein, putative 0.002 0.0005 0.0023
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0024 0.0031 0.006
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0119 0.0672 0.2436
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0057 0.0253 0.0296
Schistosoma mansoni rab6-interacting 0.0024 0.0032 0.0032
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0057 0.0253 0.0296
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0005 0.0011
Brugia malayi hypothetical protein 0.0535 0.3451 1
Loa Loa (eye worm) hypothetical protein 0.004 0.014 0.0406
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0143 0.0539
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0109 0.0598 0.0598
Trichomonas vaginalis chromobox protein, putative 0.0065 0.0304 0.1266
Entamoeba histolytica recQ family DNA helicase 0.0024 0.0031 0.0025
Brugia malayi RNA recognition motif domain containing protein 0.0071 0.0347 0.1006
Trypanosoma brucei DNA polymerase kappa, putative 0.0072 0.0354 0.1533
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0023 0.0024 0.0071
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0142 0.0535
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0142 0.0535
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.2234 1
Echinococcus multilocularis tar DNA binding protein 0.0071 0.0347 0.0347
Echinococcus multilocularis Rac GTPase activating protein 1 0.0089 0.0467 0.0467
Schistosoma mansoni acetyl-CoA synthetase 0.0024 0.0031 0.0031
Echinococcus granulosus ecdysone induced protein 78C 0.0066 0.0316 0.0316
Brugia malayi Nuclear hormone receptor E75 0.0031 0.0082 0.0237
Schistosoma mansoni transcription factor LCR-F1 0.0043 0.0163 0.0163
Brugia malayi jmjC domain containing protein 0.0115 0.0644 0.1866
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0028 0.0059 0.1195
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0051 0.0215 0.042
Loa Loa (eye worm) hypothetical protein 0.0081 0.0412 0.1193
Schistosoma mansoni hypothetical protein 0.0355 0.2246 0.2246
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0054 0.0235 0.0795
Brugia malayi Nuclear hormone receptor E75 0.0031 0.0082 0.0237
Loa Loa (eye worm) hypothetical protein 0.0033 0.009 0.0261
Trypanosoma brucei unspecified product 0.0088 0.0463 0.2001
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0043 0.0163 0.0163
Brugia malayi Pre-SET motif family protein 0.0037 0.0119 0.0344
Onchocerca volvulus 0.0031 0.0082 0.0149
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0045 0.0171 0.0551
Brugia malayi Doublecortin family protein 0.0024 0.0032 0.0092
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0066 0.0316 0.0917
Leishmania major DNA polymerase kappa, putative 0.002 0.0005 0.0023
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0256 0.1584 0.185
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0047 0.0184 0.0184
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0024 0.0031 0.006
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0066 0.0316 0.0917
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.004 0.014 0.0406
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0034 0.0102 0.0102
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0031 0.003
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.0516 0.2231
Trichomonas vaginalis CMGC family protein kinase 0.0063 0.0296 0.1232
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0353 0.2234 0.8316
Plasmodium falciparum DNA repair protein REV1, putative 0.002 0.0005 0.0033
Echinococcus granulosus chromobox protein 1 0.0098 0.0527 0.0527
Loa Loa (eye worm) hypothetical protein 0.0031 0.0082 0.0237
Echinococcus granulosus jumonji domain containing protein 0.0049 0.02 0.02
Brugia malayi Bromodomain containing protein 0.0038 0.0127 0.0368
Schistosoma mansoni alpha-glucosidase 0.0157 0.0923 0.0923
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0057 0.0146
Trypanosoma brucei DNA damage repair protein, putative 0.002 0.0005 0.0023
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0061 0.028 0.0729
Toxoplasma gondii hypothetical protein 0.0059 0.0266 0.5409
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0028 0.0057 0.0342
Onchocerca volvulus 0.0535 0.3451 1
Echinococcus granulosus Rac GTPase activating protein 1 0.0089 0.0467 0.0467
Echinococcus granulosus polycomb protein SCMH1 0.0058 0.0258 0.0258
Brugia malayi bZIP transcription factor family protein 0.0101 0.0551 0.1596
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0024 0.0031 0.003
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0031 0.0036
Loa Loa (eye worm) latrophilin receptor protein 2 0.0034 0.0102 0.0297
Schistosoma mansoni hypothetical protein 0.0074 0.0369 0.0369
Brugia malayi hypothetical protein 0.0043 0.0163 0.0472
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0035 0.0109 0.0384
Toxoplasma gondii ImpB/MucB/SamB family protein 0.002 0.0005 0.0111
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0081 0.0412 0.0475
Loa Loa (eye worm) nuclear hormone receptor 0.0031 0.0082 0.0237
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0028 0.0057 0.0164
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0063 0.0296 0.0859
Onchocerca volvulus 0.008 0.0405 0.1095
Echinococcus multilocularis beta LACTamase domain containing family member 0.004 0.014 0.014
Brugia malayi hypothetical protein 0.003 0.0076 0.022
Loa Loa (eye worm) hypothetical protein 0.004 0.014 0.0406
Loa Loa (eye worm) hypothetical protein 0.0066 0.0316 0.0917
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0066 0.0316 0.0917
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0096 0.0323
Schistosoma mansoni serine/threonine protein kinase 0.011 0.0606 0.0606
Brugia malayi jmjC domain containing protein 0.0047 0.0186 0.0539
Toxoplasma gondii histone lysine methyltransferase SET1 0.007 0.034 0.6915
Schistosoma mansoni serine/threonine protein kinase 0.0194 0.1173 0.1173
Schistosoma mansoni sex comb on midleg homolog 0.0058 0.0258 0.0258
Trypanosoma cruzi DNA polymerase kappa, putative 0.0096 0.0516 0.1006
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.014 0.0273
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0026 0.0044 0.0191
Brugia malayi AMP-binding enzyme family protein 0.0081 0.0412 0.1193
Plasmodium vivax heterochromatin protein 1, putative 0.0028 0.0057 0.0342
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0143 0.0539
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0081 0.0412 0.0481
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0161 0.0619
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0172 0.1026 0.1193
Schistosoma mansoni tar DNA-binding protein 0.0071 0.0347 0.0347
Loa Loa (eye worm) hypothetical protein 0.006 0.0275 0.0798
Echinococcus granulosus lysosomal alpha glucosidase 0.0182 0.1093 0.1093
Echinococcus granulosus lamin dm0 0.0033 0.009 0.009
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0057 0.0146
Brugia malayi RhoGAP domain containing protein 0.0089 0.0467 0.1352
Mycobacterium ulcerans hypothetical protein 0.004 0.014 0.0158
Loa Loa (eye worm) hypothetical protein 0.0095 0.0507 0.1469
Echinococcus granulosus tar DNA binding protein 0.0071 0.0347 0.0347
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0037 0.0119 0.2413
Brugia malayi ecdysteroid receptor 0.0066 0.0316 0.0917
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0057 0.0146
Schistosoma mansoni nuclear receptor 0.0031 0.0082 0.0082
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0032 0.0085 0.0085
Echinococcus multilocularis nuclear receptor nhr 48 0.0031 0.0082 0.0082
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0161 0.0619
Loa Loa (eye worm) inositol-1 0.0045 0.0171 0.0495
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0786 0.5129 1
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0282 0.1218
Brugia malayi nuclear receptor NHR-88 0.0031 0.0082 0.0237
Mycobacterium ulcerans endonuclease IV 0.0093 0.0492 0.0568
Giardia lamblia Flap structure-specific endonuclease 0.0031 0.0083 0.0289
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0115 0.0644 0.0644
Schistosoma mansoni cpg binding protein 0.0035 0.0104 0.0104
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0024 0.0031 0.0024
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0047 0.0184 0.0532
Brugia malayi nuclear receptor NHR-88 0.0066 0.0316 0.0917
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0282 0.0282
Loa Loa (eye worm) transcription factor SMAD2 0.0262 0.1624 0.4707
Echinococcus granulosus lipoxygenase domain containing protein 0.0024 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0066 0.0316 0.0917
Schistosoma mansoni hypothetical protein 0.0034 0.0102 0.0102
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0024 0.0031 0.003
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0047 0.0184 0.0184
Trypanosoma brucei unspecified product 0.0044 0.0168 0.0727
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0087 0.0284
Brugia malayi steroid hormone receptor 0.0066 0.0316 0.0917
Loa Loa (eye worm) hypothetical protein 0.0081 0.0412 0.1193
Trichomonas vaginalis CMGC family protein kinase 0.0063 0.0296 0.1232
Mycobacterium tuberculosis Probable lipase LipE 0.004 0.014 0.0164
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0031 0.0082 0.0082
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0194 0.1173 0.1173
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0031 0.0061
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0066 0.0316 0.0316
Plasmodium vivax acyl-CoA synthetase, putative 0.006 0.0275 0.1665
Schistosoma mansoni hypothetical protein 0.0034 0.0102 0.0102
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0047 0.0184 0.0184
Schistosoma mansoni alpha glucosidase 0.004 0.0143 0.0143
Echinococcus multilocularis microtubule associated protein 2 0.1514 1 1
Trypanosoma brucei PAB1-binding protein , putative 0.003 0.0076 0.0329
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0142 0.0825 0.0825
Loa Loa (eye worm) hypothetical protein 0.0057 0.0256 0.0743
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.011 0.0606 0.1756
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0024 0.0031 0.0089
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0035 0.0107 0.0107
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.004 0.0143 0.0539
Entamoeba histolytica hypothetical protein 0.0043 0.0163 0.0522
Echinococcus granulosus bloom syndrome protein 0.0079 0.0399 0.0399
Plasmodium falciparum flap endonuclease 1 0.0031 0.0083 0.05
Trichomonas vaginalis chromobox protein, putative 0.0065 0.0304 0.1266
Mycobacterium leprae Probable lipase LipE 0.004 0.014 0.0128
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0054 0.0235 0.0682
Loa Loa (eye worm) mbt repeat family protein 0.0058 0.0258 0.0747
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0282 0.5731
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0093 0.0492 0.1425
Echinococcus granulosus inositol monophosphatase 1 0.0045 0.0171 0.0171
Trypanosoma brucei DNA polymerase kappa, putative 0.0052 0.022 0.0953
Onchocerca volvulus 0.0024 0.0032 0.0003
Trypanosoma cruzi DNA damage repair protein, putative 0.002 0.0005 0.0011
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0028 0.0057 0.0057
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0081 0.0412 0.0481
Brugia malayi intermediate filament protein 0.0033 0.009 0.0261
Echinococcus granulosus SAM and MBT domain containing protein 0.0058 0.0258 0.0258
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0031 0.0082 0.0082
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.0516 0.2231
Trichomonas vaginalis DNA helicase recq1, putative 0.0079 0.0399 0.1695
Echinococcus granulosus Polycystic kidney disease protein 0.0024 0.0032 0.0032
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0066 0.0316 0.0917
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0031 0.003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0089 0.0294
Brugia malayi hypothetical protein 0.0035 0.0107 0.031
Echinococcus multilocularis jumonji domain containing protein 0.0049 0.02 0.02
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0171 0.0738
Echinococcus multilocularis Polycystic kidney disease protein 0.0024 0.0032 0.0032
Leishmania major DNA polymerase eta, putative 0.0095 0.0507 0.2192
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0031 0.003
Loa Loa (eye worm) hypothetical protein 0.0032 0.0086 0.025
Trypanosoma brucei DNA polymerase IV, putative 0.0096 0.0516 0.2231
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0096 0.0516 0.2225
Schistosoma mansoni DNA polymerase eta 0.0095 0.0507 0.0507
Schistosoma mansoni hypothetical protein 0.0034 0.0102 0.0102
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0024 0.0031 0.0133
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0035 0.0109 0.0384
Toxoplasma gondii propionate-CoA ligase 0.0024 0.0031 0.0626
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0066 0.0316 0.0316
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0194 0.1173 0.3398
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0066 0.0316 0.0917
Leishmania major mitochondrial DNA polymerase beta 0.0365 0.2313 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0066 0.0316 0.0917
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.011 0.0606 0.262
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0021 0.001 0.001
Loa Loa (eye worm) RNA binding protein 0.0071 0.0347 0.1006
Echinococcus granulosus muscleblind protein 0.018 0.1079 0.1079
Loa Loa (eye worm) hypothetical protein 0.0136 0.0783 0.2268
Loa Loa (eye worm) CHromoDomain protein family member 0.0032 0.0085 0.0247
Schistosoma mansoni retinoic acid receptor RXR 0.0066 0.0316 0.0316
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0082 0.0082
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0057 0.0146
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0057 0.0146
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0101 0.0551 0.0551
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0023 0.0024 0.0024
Giardia lamblia DNA repair protein RAD52 0.042 0.2681 1
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.014 0.0525
Brugia malayi F/Y-rich N-terminus family protein 0.0026 0.0045 0.0129
Loa Loa (eye worm) hypothetical protein 0.0031 0.0082 0.0237
Loa Loa (eye worm) hypothetical protein 0.0109 0.0599 0.1737
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0093 0.0492 0.0574
Schistosoma mansoni myelin transcription factor 1 myt1 0.0066 0.0311 0.0311
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0057 0.0342
Treponema pallidum fructose-bisphosphate aldolase 0.0353 0.2234 0.6738
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.008 0.0406 0.0406
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0109 0.0598 0.0598
Loa Loa (eye worm) hypothetical protein 0.006 0.0275 0.0798
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0076 0.0459
Echinococcus granulosus zinc finger protein 0.0026 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0061 0.028 0.0811
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0119 0.0119
Trypanosoma cruzi DNA polymerase eta, putative 0.0051 0.0211 0.0412
Onchocerca volvulus 0.0106 0.0579 0.1602
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0051 0.0215 0.042
Trypanosoma cruzi DNA polymerase kappa, putative 0.0096 0.0516 0.1006
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0058 0.0258 0.0664
Onchocerca volvulus 0.0037 0.012 0.026
Mycobacterium tuberculosis Conserved hypothetical protein 0.0064 0.0301 0.0352
Plasmodium vivax SET domain protein, putative 0.0037 0.0119 0.0717
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.2234 1
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0096 0.0323
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0028 0.0057 0.0122
Loa Loa (eye worm) jmjC domain-containing protein 0.0047 0.0186 0.0539
Trichomonas vaginalis antibiotic synthetase, putative 0.0024 0.0031 0.0029
Loa Loa (eye worm) hypothetical protein 0.0037 0.012 0.0347
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0023 0.0024 0.0047
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0089
Onchocerca volvulus 0.0024 0.0032 0.0003
Mycobacterium leprae Probable transmembrane serine/threonine-protein kinase B PknB (protein kinase B) (STPK B) 0.1298 0.856 1
Echinococcus granulosus transcription factor Dp 1 0.0046 0.0181 0.0181
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0064 0.0303 0.0303
Loa Loa (eye worm) hypothetical protein 0.0035 0.0107 0.031
Trichomonas vaginalis CMGC family protein kinase 0.0063 0.0296 0.1232
Trypanosoma brucei DNA polymerase kappa, putative 0.0052 0.022 0.0953
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0035 0.0109 0.0384
Trichomonas vaginalis Heterochromatin protein, putative 0.0028 0.0057 0.0146
Giardia lamblia DINP protein human, muc B family 0.0072 0.0354 0.1304
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0031 0.0089
Giardia lamblia Sgs1 DNA helicase, putative 0.0047 0.0184 0.0666
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.0516 0.2231
Loa Loa (eye worm) steroid hormone receptor 0.0066 0.0316 0.0917
Brugia malayi beta-lactamase family protein 0.004 0.014 0.0406
Echinococcus multilocularis lipoxygenase domain containing protein 0.0024 0.0032 0.0032
Brugia malayi CHD4 protein 0.0032 0.0085 0.0247
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.004 0.0143 0.0448
Mycobacterium ulcerans DNA polymerase IV 0.0096 0.0516 0.0597
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0023 0.0023 0.01
Trichomonas vaginalis hypothetical protein 0.0028 0.0057 0.0146
Loa Loa (eye worm) hypothetical protein 0.0031 0.0082 0.0237
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0065 0.0304 0.0799
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.008 0.0406 0.0791
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0045 0.0171 0.0898
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0024 0.0031 0.0133
Loa Loa (eye worm) hypothetical protein 0.0028 0.0057 0.0164
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0063 0.0296 0.0578
Brugia malayi Associated with TFs and helicases family protein 0.0028 0.0057 0.0164
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0031 0.0089
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0043 0.0163 0.0163
Trichomonas vaginalis set domain proteins, putative 0.0287 0.1791 0.7997
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0048 0.0196 0.398
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0024 0.0031 0.0036
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0282 0.0282
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0081 0.0412 0.0475
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.014 0.014
Mycobacterium ulcerans acyl-CoA synthetase 0.0081 0.0412 0.0475
Brugia malayi nuclear receptor RXR 0.0031 0.0082 0.0237
Brugia malayi nuclear receptor NHR-67 0.0031 0.0082 0.0237
Schistosoma mansoni intermediate filament proteins 0.0033 0.009 0.009
Schistosoma mansoni methyl-cpg binding protein mbd 0.0021 0.001 0.001
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0072 0.0354 0.0414
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0024 0.0031 0.0089
Brugia malayi SET domain containing protein 0.003 0.0071 0.0204
Trypanosoma brucei glucosidase, putative 0.004 0.0143 0.062
Brugia malayi Flap endonuclease-1 0.0031 0.0083 0.024
Schistosoma mansoni ap endonuclease 0.0023 0.0024 0.0024
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0031 0.0036
Echinococcus multilocularis lipoxygenase domain containing protein 0.0024 0.0032 0.0032
Echinococcus multilocularis dual specificity 0.011 0.0606 0.0606
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0058 0.0262 0.0759
Mycobacterium ulcerans hypothetical protein 0.0081 0.0412 0.0475
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0028 0.0057 0.0342
Echinococcus multilocularis Protein lozenge 0.0067 0.0321 0.0321
Mycobacterium ulcerans esterase/lipase LipP 0.004 0.014 0.0158
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0028 0.0057 0.1152
Brugia malayi Inositol-1 0.0045 0.0171 0.0495
Schistosoma mansoni tar DNA-binding protein 0.0071 0.0347 0.0347
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0143 0.0539
Echinococcus multilocularis RUN 0.0024 0.0032 0.0032
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0043 0.0163 0.0163
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0035 0.0108 0.0108
Mycobacterium ulcerans beta-lactamase 0.004 0.014 0.0158
Onchocerca volvulus 0.0287 0.1791 0.5147
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0066 0.0316 0.0316
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0066 0.0316 0.0917
Trypanosoma brucei DNA damage repair protein, putative 0.002 0.0005 0.0023
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0043 0.0161 0.0698
Echinococcus granulosus fetal alzheimer antigen falz 0.0029 0.0068 0.0068
Trypanosoma brucei protein kinase, putative 0.0063 0.0296 0.1282
Leishmania major 4-coumarate:coa ligase-like protein 0.0081 0.0412 0.1781
Mycobacterium ulcerans serine/threonine-protein kinase B PknB 0.1298 0.856 1
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0353 0.2234 0.8316
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0142 0.0535
Brugia malayi beta-lactamase 0.004 0.014 0.0406
Trypanosoma brucei DNA polymerase kappa, putative 0.0052 0.0221 0.0957
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0074 0.0369 0.107
Loa Loa (eye worm) CXXC zinc finger family protein 0.0035 0.0104 0.0302
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0024 0.0147
Loa Loa (eye worm) hypothetical protein 0.0066 0.0316 0.0917
Loa Loa (eye worm) hypothetical protein 0.0031 0.0082 0.0237
Plasmodium vivax flap endonuclease 1, putative 0.0031 0.0083 0.05
Loa Loa (eye worm) hypothetical protein 0.0031 0.0082 0.0237
Loa Loa (eye worm) MBCTL1 0.0066 0.0311 0.0901
Echinococcus multilocularis inositol monophosphatase 1 0.0045 0.0171 0.0171
Plasmodium falciparum heterochromatin protein 1 0.0028 0.0057 0.0342
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0093 0.0492 0.2971
Echinococcus granulosus dnaJ subfamily B 0.0494 0.3177 0.3177
Loa Loa (eye worm) hypothetical protein 0.006 0.0272 0.0788
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0057 0.0146
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0045 0.0171 0.3474
Leishmania major 4-coumarate:coa ligase-like protein 0.0081 0.0412 0.1781
Toxoplasma gondii PHD-finger domain-containing protein 0.0035 0.0108 0.2195
Schistosoma mansoni lipoxygenase 0.01 0.0539 0.0539
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.004 0.0139 0.0163
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0031 0.003
Plasmodium vivax acetyl-CoA synthetase, putative 0.0024 0.0031 0.0186
Loa Loa (eye worm) PHD-finger family protein 0.0025 0.0039 0.0113
Brugia malayi exodeoxyribonuclease III family protein 0.0023 0.0024 0.007
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0047 0.0184 0.3737
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0109 0.0598 0.0598
Trypanosoma brucei chrX additional, unordered contigs 0.002 0.0005 0.0023
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0172 0.1026 0.1199
Leishmania major acetyl-CoA synthetase, putative 0.0024 0.0031 0.0133
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0023 0.0024 0.0024
Schistosoma mansoni chromobox protein 0.0028 0.0057 0.0057
Schistosoma mansoni flap endonuclease-1 0.0028 0.0063 0.0063
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0024 0.0035 0.0102
Loa Loa (eye worm) hypothetical protein 0.006 0.0275 0.0798
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0024 0.0031 0.0031
Schistosoma mansoni steroid hormone receptor ad4bp 0.0066 0.0316 0.0316
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0054 0.0235 0.0459
Mycobacterium tuberculosis Probable lipase LipD 0.004 0.014 0.0164
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0171 0.0333
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0786 0.5129 1
Schistosoma mansoni chromobox protein 0.0098 0.0527 0.0527
Mycobacterium leprae conserved hypothetical protein 0.0024 0.0035 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0066 0.0316 0.0917
Echinococcus multilocularis dna polymerase kappa 0.0096 0.0516 0.0516
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0282 0.0323
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0057 0.0146
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0028 0.0057 0.0057
Brugia malayi Protein kinase domain containing protein 0.0194 0.1173 0.3398
Entamoeba histolytica acyl-coA synthetase, putative 0.0081 0.0412 0.1459
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.2234 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0082 0.0237
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.2234 1
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0024 0.0031 0.003
Leishmania major hypothetical protein, conserved 0.003 0.0076 0.0329
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0024 0.0031 0.003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0068 0.0198
Brugia malayi RNA binding protein 0.0071 0.0347 0.1006
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0024 0.0031 0.003
Schistosoma mansoni methyl-cpg binding protein mbd 0.0021 0.001 0.001
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0282 0.0323
Brugia malayi Calcitonin receptor-like protein seb-1 0.0109 0.0599 0.1737
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0024 0.0031 0.003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0235 0.0956
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.004 0.0143 0.0448
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0161 0.0619
Schistosoma mansoni lipoxygenase 0.0142 0.0825 0.0825
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0032 0.0085 0.0085
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0143 0.0279
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0066 0.0316 0.0917
Brugia malayi PHD-finger family protein 0.0035 0.0108 0.0313
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0054 0.0235 0.1018
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0081 0.0412 0.0475
Loa Loa (eye worm) hypothetical protein 0.0066 0.0316 0.0917
Echinococcus granulosus flap endonuclease 1 0.0031 0.0083 0.0083
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0029 0.0068 0.0068
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0066 0.0316 0.0316
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0031 0.0089
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0102
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0031 0.0082 0.0082
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0031 0.0061
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0282 0.0329
Brugia malayi ImpB/MucB/SamB family protein 0.0095 0.0507 0.1469
Trypanosoma brucei DNA polymerase kappa, putative 0.0052 0.0221 0.0957
Schistosoma mansoni rac gtpase activating protein 0.0089 0.0467 0.0467
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0066 0.0311 0.0901
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.008 0.0406 0.1754
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0068 0.0198
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0089 0.0294
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0024 0.0031 0.0089
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0054 0.0235 0.1018
Onchocerca volvulus 0.0066 0.0316 0.0835
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0028 0.0057 0.0146
Mycobacterium tuberculosis Conserved protein 0.004 0.014 0.0164
Loa Loa (eye worm) flap endonuclease-1 0.0031 0.0083 0.024
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0081 0.0412 0.0447
Echinococcus granulosus survival motor neuron protein 1 0.0286 0.1783 0.1783
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0076 0.0148
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.008 0.0406 0.1436
Echinococcus multilocularis musashi 0.0033 0.009 0.009
Trypanosoma cruzi DNA polymerase eta, putative 0.0095 0.0507 0.0989
Loa Loa (eye worm) runx1 0.0067 0.0321 0.0931
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0066 0.0316 0.0316
Entamoeba histolytica hypothetical protein 0.0119 0.0672 0.2436
Brugia malayi conserved hypotetical protein 0.0031 0.0082 0.0237
Schistosoma mansoni hypothetical protein 0.0368 0.2334 0.2334
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0054 0.0235 0.0235
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0081 0.0257
Onchocerca volvulus 0.006 0.0272 0.0705
Loa Loa (eye worm) hypothetical protein 0.0031 0.0082 0.0237
Loa Loa (eye worm) hypothetical protein 0.004 0.014 0.0406
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.008 0.0406 0.0791
Brugia malayi M-phase phosphoprotein, mpp8 0.0136 0.0783 0.2268
Brugia malayi Glycosyl hydrolases family 31 protein 0.004 0.0143 0.0415
Onchocerca volvulus Protein ultraspiracle homolog 0.0066 0.0316 0.0835
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0063 0.0296 0.1282
Brugia malayi RhoGAP domain containing protein 0.0077 0.0385 0.1116
Trichomonas vaginalis chromobox protein, putative 0.0028 0.0057 0.0146
Entamoeba histolytica acyl-CoA synthetase, putative 0.0081 0.0412 0.1459
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0074 0.0368 0.0368
Trypanosoma cruzi DNA polymerase kappa, putative 0.0096 0.0516 0.1006
Onchocerca volvulus 0.0136 0.0783 0.2199
Echinococcus multilocularis lamin dm0 0.0033 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0046 0.0182 0.0528
Loa Loa (eye worm) doublecortin family protein 0.0024 0.0032 0.0092
Echinococcus granulosus mitogen activated protein kinase 0.0063 0.0296 0.0296
Schistosoma mansoni ap endonuclease 0.0023 0.0024 0.0024
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0053 0.0228 0.0445
Brugia malayi nuclear hormone receptor 0.0031 0.0082 0.0237
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0024 0.0031 0.0626
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0066 0.0311 0.0311
Mycobacterium tuberculosis Transmembrane serine/threonine-protein kinase B PknB (protein kinase B) (STPK B) 0.1298 0.856 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0142 0.0535
Trichomonas vaginalis CMGC family protein kinase 0.0063 0.0296 0.1232
Loa Loa (eye worm) hypothetical protein 0.018 0.1079 0.3127
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0057 0.0342
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0045 0.0171 0.0193
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0031 0.0082 0.0082
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0068 0.02
Leishmania major acetyl-CoA synthetase, putative 0.0024 0.0031 0.0133
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0194 0.1173 0.3398
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0072 0.0354 0.1533
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0024 0.0031 0.0036
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0194 0.1173 0.1173
Loa Loa (eye worm) hypothetical protein 0.0035 0.0107 0.031
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0031 0.0083 0.0358
Loa Loa (eye worm) hypothetical protein 0.004 0.014 0.0406
Brugia malayi ecdysone receptor 0.0031 0.0082 0.0237
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0024 0.0147
Schistosoma mansoni lamin 0.0033 0.009 0.009
Loa Loa (eye worm) bromodomain containing protein 0.0021 0.0015 0.0044
Loa Loa (eye worm) hypothetical protein 0.0058 0.0258 0.0747
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.004 0.014 0.0158
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0108 0.0652
Mycobacterium ulcerans bifunctional membrane-associated penicillin-binding protein 1A/1B PonA2 0.0513 0.3303 0.3855
Loa Loa (eye worm) hypothetical protein 0.0052 0.022 0.0638
Brugia malayi hypothetical protein 0.0031 0.0082 0.0237
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0031 0.0083 0.0358
Echinococcus multilocularis muscleblind protein 0.018 0.1079 0.1079
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0051 0.0215 0.0932
Brugia malayi photoreceptor-specific nuclear receptor 0.0066 0.0316 0.0917
Loa Loa (eye worm) hypothetical protein 0.0049 0.0201 0.0584
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0081 0.0412 0.0447
Onchocerca volvulus 0.0033 0.009 0.0174
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0282 0.0282
Loa Loa (eye worm) hypothetical protein 0.0093 0.0492 0.1425
Mycobacterium ulcerans hypothetical protein 0.0192 0.1158 0.1347
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0045 0.0171 0.0663
Mycobacterium ulcerans hypothetical protein 0.0024 0.0035 0.0035
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0028 0.0057 0.0146
Wolbachia endosymbiont of Brugia malayi 3-methyladenine DNA glycosylase 0.0266 0.1655 1
Entamoeba histolytica hypothetical protein 0.0028 0.0057 0.0122
Trypanosoma cruzi DNA damage repair protein, putative 0.002 0.0005 0.0011
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0024 0.0031 0.006
Echinococcus multilocularis mitogen activated protein kinase 0.0063 0.0296 0.0296
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.004 0.0143 0.0539
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.011 0.0606 0.1181
Echinococcus granulosus thyroid hormone receptor alpha 0.0031 0.0082 0.0082
Brugia malayi mbt repeat family protein 0.0058 0.0258 0.0747
Echinococcus multilocularis muscleblind protein 1 0.018 0.1079 0.1079
Schistosoma mansoni chromobox protein 0.0028 0.0057 0.0057
Brugia malayi ImpB/MucB/SamB family protein 0.0064 0.0301 0.0873
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0035 0.0107 0.0107
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0024 0.0031 0.0036
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0282 0.0282
Echinococcus granulosus RUN 0.0024 0.0032 0.0032
Echinococcus granulosus chromobox protein 1 0.0098 0.0527 0.0527
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0194 0.1173 0.3338
Echinococcus granulosus histone acetyltransferase MYST2 0.0066 0.0311 0.0311
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0232 0.1422 0.1422
Echinococcus multilocularis dnaJ subfamily B 0.0494 0.3177 0.3177
Loa Loa (eye worm) hypothetical protein 0.0031 0.0082 0.0237
Echinococcus multilocularis cpg binding protein 0.0039 0.0133 0.0133
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0057 0.0146
Plasmodium vivax multidomain scavenger receptor, putative 0.0024 0.0032 0.0191
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0075 0.0373 0.0373
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.2234 1
Schistosoma mansoni zinc finger protein 0.0031 0.0082 0.0082
Trypanosoma brucei DNA polymerase IV, putative 0.0088 0.0463 0.2001
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.004 0.014 0.0164
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0024 0.0031 0.0036
Brugia malayi AMP-binding enzyme family protein 0.0081 0.0412 0.1193
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0173 0.1027 0.4442
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0053 0.0228 0.0987
Brugia malayi chromobox protein homolog 3 0.0061 0.028 0.0811
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0024 0.0031 0.0186
Brugia malayi Muscleblind-like protein 0.018 0.1079 0.3127
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0058 0.0258 0.0258
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0076 0.0459
Schistosoma mansoni loxhd1 0.0024 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0085 0.0444 0.1286
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0786 0.5129 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.006 0.0275 0.0316
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0024 0.0035 0.0013
Schistosoma mansoni nuclear receptor nhr-48 0.0031 0.0082 0.0082
Echinococcus multilocularis jun protein 0.0101 0.0551 0.0551
Trypanosoma brucei DNA polymerase kappa, putative 0.0096 0.0516 0.2231
Echinococcus multilocularis neutral alpha glucosidase AB 0.004 0.0143 0.0143
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0063 0.0296 0.1282
Loa Loa (eye worm) hypothetical protein 0.0035 0.0107 0.031
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0066 0.0316 0.0917
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0066 0.0316 0.0316
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0365 0.2313 0.4509
Brugia malayi Nuclear hormone receptor-like 1 0.0066 0.0316 0.0917
Trichomonas vaginalis chromobox protein, putative 0.0028 0.0057 0.0146
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.014 0.0273
Entamoeba histolytica hypothetical protein 0.0028 0.0057 0.0122
Mycobacterium ulcerans DNA polymerase IV 0.0096 0.0516 0.0597
Leishmania major DNA polymerase eta, putative 0.0051 0.0211 0.0914
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0142 0.0535
Brugia malayi hypothetical protein 0.0031 0.0082 0.0237
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0066 0.0316 0.0316
Toxoplasma gondii endonuclease IV APN 0.0093 0.0492 1
Mycobacterium leprae POSSIBLE 3-METHYLADENINE DNA GLYCOSYLASE MPG 0.0135 0.0777 0.0875
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0101 0.0551 0.0551
Schistosoma mansoni jumonji/arid domain-containing protein 0.0047 0.0186 0.0186
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0057 0.0146
Plasmodium falciparum DNA-3-methyladenine glycosylase, putative 0.0266 0.1655 1
Brugia malayi hypothetical protein 0.008 0.0405 0.1174
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0064 0.0301 0.0301
Brugia malayi nuclear hormone receptor family member odr-7 0.0031 0.0082 0.0237
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0057 0.0253 0.0296
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0047 0.0184 0.0532
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0182 0.1093 0.3168
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0024 0.0031 0.0036
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0089
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0054 0.0235 0.1018
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0035 0.0109 0.0384
Loa Loa (eye worm) hypothetical protein 0.0066 0.0316 0.0917
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0024 0.0031 0.006
Loa Loa (eye worm) hypothetical protein 0.0535 0.3451 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0057 0.0164
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0161 0.0619
Loa Loa (eye worm) hypothetical protein 0.0028 0.0057 0.0164
Plasmodium falciparum LCCL domain-containing protein 0.0024 0.0032 0.0191
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.008 0.0406 0.1176
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.014 0.0525
Loa Loa (eye worm) MH2 domain-containing protein 0.0262 0.1624 0.4707
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.014 0.014
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0031 0.003
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0031 0.003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0066 0.0316 0.0917
Schistosoma mansoni inositol monophosphatase 0.0045 0.0171 0.0171
Echinococcus granulosus neuropeptide receptor A26 0.0558 0.3609 0.3609
Echinococcus granulosus lipoxygenase domain containing protein 0.0024 0.0032 0.0032
Mycobacterium ulcerans lipase LipD 0.004 0.014 0.0158
Schistosoma mansoni zinc finger protein 0.0026 0.0044 0.0044
Loa Loa (eye worm) RecQ helicase 0.0079 0.0399 0.1156
Entamoeba histolytica hypothetical protein 0.0043 0.0163 0.0522
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0066 0.0316 0.0316
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0047 0.0184 0.0184
Schistosoma mansoni coup transcription factor 0.0066 0.0316 0.0316
Brugia malayi CXXC zinc finger family protein 0.0035 0.0104 0.0302
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0024 0.0031 0.0036
Brugia malayi Glycosyl hydrolases family 31 protein 0.0182 0.1093 0.3168
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0109 0.0384
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0023 0.0024 0.0028
Echinococcus granulosus lamin 0.0033 0.009 0.009
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0031 0.0083 0.1683
Schistosoma mansoni rab6-interacting 0.0024 0.0032 0.0032
Echinococcus granulosus lysine specific demethylase 5A 0.0047 0.0186 0.0186
Mycobacterium tuberculosis Probable hydrolase 0.004 0.014 0.0164
Loa Loa (eye worm) pax transcription factor protein 2 0.0291 0.1817 0.5265
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.009
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0023 0.0024 0.007
Plasmodium vivax DNA repair protein REV1, putative 0.002 0.0005 0.0033
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.011 0.0606 0.262
Brugia malayi Nuclear hormone receptor-like 1 0.0035 0.0107 0.031
Onchocerca volvulus 0.0136 0.0783 0.2199
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0109 0.0384
Onchocerca volvulus 0.0058 0.0258 0.0664
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0068 0.02
Loa Loa (eye worm) hypothetical protein 0.0034 0.0102 0.0297
Onchocerca volvulus 0.0035 0.0104 0.0215
Brugia malayi mbt repeat family protein 0.0058 0.0258 0.0747
Loa Loa (eye worm) helicase 0.0028 0.0057 0.0164
Onchocerca volvulus 0.0064 0.0303 0.0796
Schistosoma mansoni blooms syndrome DNA helicase 0.0024 0.0031 0.0031
Mycobacterium ulcerans 3-methyladenine DNA glycosylase 0.0266 0.1655 0.1928
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0066 0.0316 0.0316
Trichomonas vaginalis antibiotic synthetase, putative 0.0024 0.0031 0.0029
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0082 0.0082
Treponema pallidum hypothetical protein 0.0513 0.3303 1
Brugia malayi Nuclear hormone receptor-like 1 0.0035 0.0107 0.031
Loa Loa (eye worm) hypothetical protein 0.003 0.0076 0.022
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0033 0.009 0.0261
Entamoeba histolytica hypothetical protein 0.0043 0.0163 0.0522
Brugia malayi Protein cec-1. 0.0028 0.0057 0.0164
Schistosoma mansoni serine/threonine protein kinase 0.0063 0.0296 0.0296
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.004 0.014 0.0406
Loa Loa (eye worm) nuclear receptor NHR-67 0.0031 0.0082 0.0237
Loa Loa (eye worm) DR-78 0.0031 0.0082 0.0237
Echinococcus granulosus Nuclear hormone receptor HR96 0.0031 0.0082 0.0082
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0062 0.0291 0.0566
Loa Loa (eye worm) hypothetical protein 0.0031 0.0082 0.0237
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0035 0.0107 0.031
Brugia malayi Bromodomain containing protein 0.0046 0.0182 0.0527
Plasmodium falciparum phd finger protein, putative 0.0035 0.0108 0.0652
Mycobacterium tuberculosis Probable esterase LipL 0.004 0.014 0.0164
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.2234 1
Schistosoma mansoni terminal deoxycytidyl transferase 0.0064 0.0301 0.0301
Trichomonas vaginalis DNA-3-methyladenine glycosylase, putative 0.0266 0.1655 0.7379
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0031 0.0082 0.0237
Mycobacterium tuberculosis Conserved protein 0.004 0.014 0.0164
Loa Loa (eye worm) hypothetical protein 0.0066 0.0311 0.0901
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0031 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0535 0.3451 1
Schistosoma mansoni DNA polymerase IV / kappa 0.002 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.006 0.0275 0.0798
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0057 0.0256 0.0256
Echinococcus multilocularis FTZ F1 alpha 0.0066 0.0316 0.0316
Echinococcus multilocularis transcription factor Dp 1 0.0046 0.0181 0.0181
Giardia lamblia Kinase, CMGC MAPK 0.0063 0.0296 0.1088
Loa Loa (eye worm) hypothetical protein 0.0089 0.0467 0.1352
Echinococcus multilocularis lysosomal alpha glucosidase 0.0182 0.1093 0.1093
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0235 0.0956
Echinococcus multilocularis Chromobox protein 3 0.0028 0.0057 0.0057
Echinococcus granulosus methyl CpG binding domain protein 2 0.0021 0.001 0.001

Activities

Activity type Activity value Assay description Source Reference
AC50 (functional) < 0.15 uM PubChem BioAssay. FRET-based HTS for detection of RAD52 Inhibitors Measured in Biochemical System Using Plate Reader - 7018-01_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) ChEMBL. No reference
AC50 (functional) = 0.69 uM PubChem BioAssay. HTS for PAX8 inhibitors using PAX8 luciferase reporter gene assay in RMG-I cells Measured in Cell-Based System Using Plate Reader - 7054-01_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) ChEMBL. No reference
AC50 (functional) = 1.362 uM PUBCHEM_BIOASSAY: 24 hour HeLa Cytotox assay Measured in Cell-Based System Using Plate Reader - 2117-03_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504431] ChEMBL. No reference
AC50 (binding) = 9.515 uM PUBCHEM_BIOASSAY: MLPCN Dyrk1A Kinase Measured in Biochemical System Using Plate Reader - 2124-01_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504442] ChEMBL. No reference
GI50 (functional) -8.45 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the P388 Leukemia cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -8.106 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -7.986 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -7.941 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -7.751 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -7.75 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -7.472 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -7.178 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -6.631 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -6.523 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
IC50 (functional) = 2.4 nM Antitrypanosomal activity against bloodstream form of Trypanosoma brucei brucei 427 after 3 days by Alamar Blue assay ChEMBL. 23927763
IC50 (binding) = 50.9 nM Inhibition of recombinant PIM1 (unknown origin) expressed in Escherichia coli BL21(DE3) after 1 hr by HTRF assay ChEMBL. 23442188
IC50 (functional) = 0.1 uM Cytotoxicity against human LoVo cells under oxic condition assessed as growth inhibition after 74 hrs by sulforhodamine B assay ChEMBL. 22011244
IC50 (functional) = 0.1 uM Cytotoxicity against doxorubicin-sensitive human MCF7 cells under oxic condition assessed as growth inhibition after 74 hrs by sulforhodamine B assay ChEMBL. 22011244
IC50 (functional) = 0.9 uM Cytotoxicity against human LoVo cells under hypoxic condition assessed as growth inhibition after 74 hrs by sulforhodamine B assay ChEMBL. 22011244
IC50 (functional) = 1 uM Cytotoxicity against doxorubicin-sensitive human MCF7 cells under hypoxic condition assessed as growth inhibition after 74 hrs by sulforhodamine B assay ChEMBL. 22011244
IC50 (functional) = 1 uM Trypanocidal activity against Trypanosoma brucei brucei by Alamar Blue assay ChEMBL. 23927763
IC50 (functional) 1.101 uM PUBCHEM_BIOASSAY: Discovery of Small Molecule Probes for H1N1 Influenza NS1A. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504399] ChEMBL. No reference
IC50 (binding) = 2.5 uM Inhibition of human purified MPG pre-incubated with compound for 10 mins followed by addition of 1,N6 ethenoadenine containing 32P-labeled duplex oligonucleotide substrates by gel-based excision activity assay ChEMBL. 25650313
IC50 (functional) = 4.7 uM Cytotoxicity against doxorubicin-resistant human MCF7 cells under oxic condition assessed as growth inhibition after 74 hrs by sulforhodamine B assay ChEMBL. 22011244
IC50 (functional) > 10 uM Cytotoxicity against doxorubicin-resistant human MCF7 cells under hypoxic condition assessed as growth inhibition after 74 hrs by sulforhodamine B assay ChEMBL. 22011244
IC50 (functional) 14.81 uM PubChem BioAssay. Discovery of small molecule inhibitors of the oncogenic and cytokinetic protein MgcRacGAP - Primary and Confirmatory Screens. (Class of assay: confirmatory) ChEMBL. No reference
ILS (functional) > 272 % Antitumor activity against mouse B16 cells allografted in BDF1 mouse assessed as increase of median life span at 0.8 mg/kg, ip on day 1 to 9 measured up to 80 days relative to control ChEMBL. 490545
Potency (functional) = 0.1995 um PUBCHEM_BIOASSAY: qHTS Assay for Enhancers of SMN2 Splice Variant Expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 0.2512 um PUBCHEM_BIOASSAY: qHTS Assay for Enhancers of SMN2 Splice Variant Expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 0.2818 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] ChEMBL. No reference
Potency (functional) 0.3162 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 0.5117 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 0.7079 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference
Potency (functional) = 0.7943 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 0.8275 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 0.9285 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 0.9466 uM PubChem BioAssay. qHTS for Inhibitors of WRN Helicase. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 0.9528 uM PubChem BioAssay. qHTS Assay for the Inhibitors of FEN1: Confirmatory Assay for Cherry-picked Compounds. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 1.122 um PUBCHEM_BIOASSAY: qHTS Fluorescence Polarization Assay for Inhibitors of MLL CXXC domain - DNA interaction. (Class of assay: confirmatory) [Related pubchem assays: 2698 (Summary assay.)] ChEMBL. No reference
Potency (functional) 1.122 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference
Potency (functional) 1.1917 uM PubChem BioAssay. qHTS for Inhibitors of Polymerase Kappa: Confirmatory Assay for Cherry-picked Compounds. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 1.3115 uM PUBCHEM_BIOASSAY: Quantitative high throughput screen for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774] ChEMBL. No reference
Potency (functional) 1.4125 uM PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Human Flap endonuclease 1 (FEN1). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488813] ChEMBL. No reference
Potency (functional) 1.4125 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Kappa. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588638] ChEMBL. No reference
Potency (functional) 1.4516 uM PubChem BioAssay. Acumen qHTS Assay for Inhibitors of the mTORC1 Signaling Pathway in WT MEF Cells: Hit Validation. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 1.4581 uM PubChem BioAssay. qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 1.5003 uM PubChem BioAssay. qHTS for Inhibitors of Polymerase Iota: Confirmatory Assay for Cherry-picked Compounds. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) 1.5849 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of MBNL1-poly(CUG) RNA binding: Initial hit validation from the primary screen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2675, AID2700] ChEMBL. No reference
Potency (functional) 1.5849 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) 1.5849 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Eta. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588636] ChEMBL. No reference
Potency (functional) = 1.7783 um PUBCHEM_BIOASSAY: qHTS Assay for Identifying the Cell-Membrane Permeable IMPase Inhibitors: Potentiation with Lithium. (Class of assay: confirmatory) [Related pubchem assays: 901 ] ChEMBL. No reference
Potency (functional) = 1.9953 um PUBCHEM_BIOASSAY: Confirmation qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) [Related pubchem assays: 1705 (qHTS Validation Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1) ), 2324 (Probe Development Summary of Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1)), 1707 (Counterscreen for APE1 Inhibitors: Fluorescent Dye Displacement Validation Assay), 2517 (qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1)), 1708 (Counterscreen for APE1 Inhibitors: qHTS Validation Assay for Inhibitors of Endonuclease IV)] ChEMBL. No reference
Potency (functional) = 1.9953 um PUBCHEM_BIOASSAY: Counterscreen for APE1 Inhibitors: qHTS Validation Assay for Inhibitors of Endonuclease IV. (Class of assay: confirmatory) [Related pubchem assays: 1705, 1707 ] ChEMBL. No reference
Potency (functional) = 1.9953 um PUBCHEM_BIOASSAY: qHTS Validation Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) [Related pubchem assays: 1707, 1708 ] ChEMBL. No reference
Potency (functional) 1.9953 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] ChEMBL. No reference
Potency (functional) 2.0371 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 2.0787 uM PUBCHEM_BIOASSAY: Quantitative high throughput screen for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488774] ChEMBL. No reference
Potency (functional) = 2.2387 um PUBCHEM_BIOASSAY: qHTS Assay for Identifying the Cell-Membrane Permeable IMPase Inhibitors: Potentiation with Lithium. (Class of assay: confirmatory) [Related pubchem assays: 901 ] ChEMBL. No reference
Potency (functional) 2.6679 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 2.8184 um PUBCHEM_BIOASSAY: Confirmation qHTS Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1). (Class of assay: confirmatory) [Related pubchem assays: 593 (Fluorescein region spectral profiling screen), 594 (Rhodamine region spectral profiling screen), 2367 (Probe Development Summary for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1)), 2353 (qHTS Validation Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1)), 2549 (qHTS Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1))] ChEMBL. No reference
Potency (functional) 2.8184 uM PUBCHEM_BIOASSAY: qHTS Validation Assay for Inhibitors for MPP8 Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) = 3.1623 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 3.1623 um PUBCHEM_BIOASSAY: Counterscreen qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. This assay monitors tau fibrillation by fluorescence polarization (FP) of Alexa 594-labeled K18 P301L, which does not fibrillize readily but incorporates into growing filaments of unlabeled tau. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (binding) = 3.1623 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) = 3.1623 um PUBCHEM_BIOASSAY: qHTS Validation Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1). (Class of assay: confirmatory) [Related pubchem assays: 593 (Fluorescein region spectral profiling screen), 594 (Rhodamine region spectral profiling screen)] ChEMBL. No reference
Potency (functional) 3.2497 uM PubChem BioAssay. Acumen qHTS Assay for Inhibitors of the mTORC1 Signaling Pathway in MEF (Tsc2-/-, p53-/-) Cells: Hit Validation. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 3.5481 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1). (Class of assay: confirmatory) [Related pubchem assays: 594 (Rhodamine region spectral profiling screen), 593 (Fluorescein region spectral profiling screen), 2367 (Probe Development Summary for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1)), 2353 (qHTS Validation Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1))] ChEMBL. No reference
Potency (functional) 3.9811 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of 15-hLO-2 (15-human lipoxygenase 2). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2312, AID2537, AID2702] ChEMBL. No reference
Potency (functional) 3.9811 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 5.0119 um PUBCHEM_BIOASSAY: VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 5.0119 um PUBCHEM_BIOASSAY: qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Permissive Temperature. (Class of assay: confirmatory) [Related pubchem assays: 902 ] ChEMBL. No reference
Potency (functional) 5.0119 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] ChEMBL. No reference
Potency (functional) 5.0738 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 5.3538 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the AP-1 signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 6.3096 um PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Lamin A Splicing. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 7.0795 um PUBCHEM_BIOASSAY: Validation of Assay for Modulators of Lamin A Splicing. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 7.0795 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] ChEMBL. No reference
Potency (functional) 7.9433 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of BAZ2B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504391] ChEMBL. No reference
Potency (functional) 7.9433 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 8.0414 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway using the MDA cell line. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) = 8.9125 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) = 8.9125 um PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of L3MBTL1. (Class of assay: confirmatory) [Related pubchem assays: 485292 (Probe Development Summary for Inhibitors of L3MBTL1)] ChEMBL. No reference
Potency (functional) 8.9125 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Eta. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588636] ChEMBL. No reference
Potency (functional) 9.5283 uM PubChem BioAssay. qHTS for Inhibitors of Polymerase Eta: Confirmatory Assay for Cherry-picked Compounds. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) = 10 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: Counterscreen qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. This assay monitors tau fibrillation by fluorescence polarization (FP) of Alexa 594-labeled K18 P301L, which does not fibrillize readily but incorporates into growing filaments of unlabeled tau. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Bloom's syndrome helicase (BLM). (Class of assay: confirmatory) [Related pubchem assays: 593 (Fluorescein region spectral profiling screen), 2386 (Probe Development Summary for Inhibitors of Bloom's syndrome helicase (BLM)), 594 (Rhodamine region spectral profiling screen), 2364 (qHTS Validation Assay for Inhibitors of Bloom's syndrome helicase (BLM))] ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS Assay for Antagonists of the Neuropeptide S Receptor: cAMP Signal Transduction. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: Validation screen for small molecules that induce DNA re-replication in MCF 10A normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 10 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference
Potency (functional) 10.6213 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of the vitamin D receptor (VDR): Hit Validation in Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 11.2202 um PUBCHEM_BIOASSAY: Counterscreen for Luciferase (Kinase-Glo TM) Inhibition. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 11.2202 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) 11.2202 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) 11.8823 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 12.5893 um PUBCHEM_BIOASSAY: Counterscreen for Luciferase (Kinase-Glo TM) Inhibition. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 12.5893 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 12.5893 um PUBCHEM_BIOASSAY: qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 12.5893 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 14.1254 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Kappa. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588638] ChEMBL. No reference
Potency (binding) 14.1254 uM PubChem BioAssay. qHTS Assay for Inhibitors of MBNL1-poly(CUG) RNA binding. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 15.8489 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 15.8489 uM PUBCHEM_BIOASSAY: Inhibitors of the vitamin D receptor (VDR): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504855] ChEMBL. No reference
Potency (functional) 16.3535 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that induce genotoxicity in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493106, AID493143] ChEMBL. No reference
Potency (functional) = 17.7407 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Fructose-1,6-bisphosphate Aldolase from Giardia Lamblia. (Class of assay: confirmatory) [Related pubchem assays: 2472, 2464 ] ChEMBL. No reference
Potency (functional) = 17.7828 um PUBCHEM_BIOASSAY: qHTS Validation Assay for Identification of Novel General Anesthetics. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 17.7828 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) 17.7828 uM PUBCHEM_BIOASSAY: qHTS Assay for Compounds Blocking the Interaction Between CBF-beta and RUNX1 for the Treatment of Acute Myeloid Leukemia. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1484, AID504370, AID504374, AID504375] ChEMBL. No reference
Potency (functional) 17.7828 uM PubChem BioAssay. qHTS of alpha-syn Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 18.3564 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) 18.3564 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of the vitamin D receptor (VDR): Hit Validation using a Beta-Lactamase Assay. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 19.0115 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) = 19.9526 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay; Stimulation with EGF. (Class of assay: confirmatory) [Related pubchem assays: 995 ] ChEMBL. No reference
Potency (functional) = 19.9526 um PUBCHEM_BIOASSAY: qHTS Validation Assay for Inhibitors of Bloom's syndrome helicase (BLM). (Class of assay: confirmatory) [Related pubchem assays: 593 (Fluorescein region spectral profiling screen), 594 (Rhodamine region spectral profiling screen)] ChEMBL. No reference
Potency (functional) = 19.9526 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Bloom's syndrome helicase (BLM). (Class of assay: confirmatory) [Related pubchem assays: 593 (Fluorescein region spectral profiling screen), 2386 (Probe Development Summary for Inhibitors of Bloom's syndrome helicase (BLM)), 594 (Rhodamine region spectral profiling screen), 2364 (qHTS Validation Assay for Inhibitors of Bloom's syndrome helicase (BLM))] ChEMBL. No reference
Potency (functional) 19.9526 uM PUBCHEM_BIOASSAY: Inhibitors of the vitamin D receptor (VDR): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504855] ChEMBL. No reference
Potency (functional) 19.9526 uM PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 22.3872 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1). (Class of assay: confirmatory) [Related pubchem assays: 594 (Rhodamine region spectral profiling screen), 593 (Fluorescein region spectral profiling screen), 2367 (Probe Development Summary for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1)), 2353 (qHTS Validation Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1))] ChEMBL. No reference
Potency (functional) = 22.3872 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 23.9145 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the NFkB signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Ubiquitin-specific Protease USP2a. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 26.8545 um PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Human Peripheral Myelin Protein 22 (PMP22) Expression/Activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 28.1838 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of GCN5L2. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504398] ChEMBL. No reference
Potency (binding) 28.1838 uM PUBCHEM_BIOASSAY: qHTS Assay for Compounds Blocking the Interaction Between CBF-beta and RUNX1 for the Treatment of Acute Myeloid Leukemia. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1484, AID504370, AID504374, AID504375] ChEMBL. No reference
Potency (functional) 28.1838 uM PUBCHEM_BIOASSAY: Inhibitors of Regulator of G Protein Signaling (RGS) 4: qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504856] ChEMBL. No reference
Potency (functional) 28.1838 uM PubChem BioAssay. qHTS for Inhibitors of Glutaminase (GLS). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 29.847 uM PubChem BioAssay: Tox21. qHTS assay for small molecule activators of the heat shock response signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Fluorescein Labeled MLL-derived Peptide. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Influenza NS1 Protein Function. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 35.4813 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of the vitamin D receptor (VDR): Hit Validation using a Texas Red Assay. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 35.4813 uM PubChem BioAssay. qHTS for Antagonists of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 35.4813 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of RanGTP induced Rango (Ran-regulated importin-beta cargo) - Importin beta complex dissociation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540262] ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (binding) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] ChEMBL. No reference
Potency (functional) = 44.6684 um PUBCHEM_BIOASSAY: Confirmation qHTS Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1). (Class of assay: confirmatory) [Related pubchem assays: 593 (Fluorescein region spectral profiling screen), 594 (Rhodamine region spectral profiling screen), 2367 (Probe Development Summary for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1)), 2353 (qHTS Validation Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1)), 2549 (qHTS Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1))] ChEMBL. No reference
Potency (functional) 56.2341 uM PUBCHEM_BIOASSAY: Inhibitors of USP1/UAF1: Pilot qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504878] ChEMBL. No reference
Potency (functional) 79.4328 uM PubChem BioAssay. qHTS Assay to Find Inhibitors of Pin1. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 141.2538 uM PubChem BioAssay. qHTS of PTHR Inhibitors: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Trypanosoma brucei gambiense 23927763
Homo sapiens ChEMBL23 22011244
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

Affected Entity Phenotypic quality Occurs in Occurs at Evidence Observed in Targets
growth (GO:0040007) decreased (PATO:0000468) inferred from in vitro culture assay (ECO:0000182) Mycobacterium tuberculosis 256653  
Annotator: crowther@u.washington.edu Comment: 2007-12-31 References: 16674948 16980473
growth (GO:0040007) decreased (PATO:0000468) inferred from in vitro culture assay (ECO:0000182) Mycobacterium aurum 256653  
Annotator: crowther@u.washington.edu Comment: 2007-12-31 References: 16674948 16980473
growth (GO:0040007) decreased (PATO:0000468) inferred from in vitro culture assay (ECO:0000182) Mycobacterium smegmatis 256653  
Annotator: crowther@u.washington.edu Comment: 2007-12-31 References: 11750829 16674948 16980473
catalytic activity (GO:0003824) decreased (PATO:0000468) in vitro (MI:0492) inferred from specific protein inhibition (ECO:0000020) Mycobacterium tuberculosis 256653  
Annotator: crowther@u.washington.edu Comment: 2007-12-31 References: 16674948 16980473
growth (GO:0040007) decreased (PATO:0000468) inferred from in vitro culture assay (ECO:0000182) Mycobacterium smegmatis 6795  
Annotator: crowther@u.washington.edu Comment: 2007-12-31 References: 11750829 16674948 16980473
catalytic activity (GO:0003824) decreased (PATO:0000468) in vitro (MI:0492) inferred from specific protein inhibition (ECO:0000020) Mycobacterium tuberculosis 6795  
Annotator: crowther@u.washington.edu Comment: 2007-12-31 References: 16674948 16980473
growth (GO:0040007) decreased (PATO:0000468) inferred from in vitro culture assay (ECO:0000182) Mycobacterium tuberculosis 6795  
Annotator: crowther@u.washington.edu Comment: 2007-12-31 References: 16674948 16980473
growth (GO:0040007) decreased (PATO:0000468) inferred from in vitro culture assay (ECO:0000182) Mycobacterium aurum 6795  
Annotator: crowther@u.washington.edu Comment: 2007-12-31 References: 16674948 16980473

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

9 literature references were collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.