WARNING: This list was made prior to the version 4 release of TDR
Targets (Aug, 2010). Some queries included in this list may not work properly.
Most likely reasons for this are changes in parameters, and/or data updates. If you
experience any problem, please try re-running each search from the search
page. You can also access the previous version of the database at
A list of potential Plasmodium protease drug targets.
*NB Relies on the word "protease" or "peptidase" appearing in gene name to identify proteases - maybe also possible with EC numbers?
The weighting is
In Plasmodium, has a name like âpeptidaseâ: 100
In Plasmodium, has a name like âproteaseâ: 100
has literature: 30
has modelled or solved structure: 50
druggability >0.3: 50
no orthologues in mammals: 50
essential in some organism: 30