Complete set of pfal queries with weighted combinations

Posted by Dany Shanmugam on 2008-04-06 01:33:33

WARNING: This list was made prior to the version 4 release of TDR Targets (Aug, 2010). Some queries included in this list may not work properly. Most likely reasons for this are changes in parameters, and/or data updates. If you experience any problem, please try re-running each search from the search page. You can also access the previous version of the database at v3.tdrtargets.org

This published set contains a comprehensive set of queries from Pfal that have been weighted 1 against all pfal genes weighted 0. The Query titles are descriptive of the weighting and combinations. This data set is useful for making a spread sheet of pfal genes with ability to adjust the weighting to allow re-ranking of target genes.

Queries in this set

Click on the links below to browse the contents of each query. You can also use the checkboxes to select queries you would like to import into your history.
Import ranked queries into your history to redo the scoring strategy

Select: All, None.

  Mwt < 100kDa (4076 records). Show parameters.

  No TM domains (3886 records). Show parameters.

  Experimental X-str available (77 records). Show parameters.

  Modbase str model available (4829 records). Show parameters.

  Top 20% expressed in early ring (974 records). Show parameters.

  Top 20% expressed in early Schizont (1032 records). Show parameters.

  Top 20% expressed in early Trophozoite (1016 records). Show parameters.

  Top 20% expressed in late ring (988 records). Show parameters.

  Top 20% expressed in late Schizont (984 records). Show parameters.

  Top 20% expressed in late Trophozoite (1025 records). Show parameters.

  Top 20% expressed in merozoites (1096 records). Show parameters.

  Presnt in P. vivax (4540 records). Show parameters.

  Absent in humans (3495 records). Show parameters.

  Essential in any species (1162 records). Show parameters.

  dindex > 0 (127 records). Show parameters.

  dindex > 0.1 (127 records). Show parameters.

  dindex > 0.2 (127 records). Show parameters.

  dindex > 0.3 (127 records). Show parameters.

  dindex > 0.4 (127 records). Show parameters.

  dindex > 0.5 (127 records). Show parameters.

  dindex > 0.6 (127 records). Show parameters.

  dindex > 0.7 (57 records). Show parameters.

  dindex > 0.8 (57 records). Show parameters.

  dindex > 0.9 (6 records). Show parameters.

  Cindex > 0 (138 records). Show parameters.

  Cindex > 0.1 (133 records). Show parameters.

  Cindex > 0.2 (113 records). Show parameters.

  Cindex > 0.3 (88 records). Show parameters.

  Cindex > 0.4 (70 records). Show parameters.

  Cindex > 0.5 (52 records). Show parameters.

  Cindex > 0.6 (23 records). Show parameters.

  Cindex > 0.7 (8 records). Show parameters.

  Cindex > 0.8 (2 records). Show parameters.

  Similar to Drugbank targets (115 records). Show parameters.

  Validation data available (107 records). Show parameters.

  Enzyme assay available (205 records). Show parameters.

  Recombinant protein expressed (136 records). Show parameters.

  Publication available (374 records). Show parameters.

  Isoelectric point (5496 records). Show parameters.

  Predicted to have Signal Peptide (834 records). Show parameters.

  Predicted to have GPI anchor (47 records). Show parameters.

  Have >1 paralog (844 records). Show parameters.

  All P. falciparum genes (5590 records). Show parameters.

  Genes with any EC number (574 records). Show parameters.

  Uploaded list of Top 20% expressed in erythrocytic stage (including merozoite stage) (1849 records). Show parameters.