Ranked list of T. brucei targets (focused on glycolytic flux) for PLOS-NTD

Posted by Dany Shanmugam on 2009-10-10 16:28:28

WARNING: This list was made prior to the version 4 release of TDR Targets (Aug, 2010). Some queries included in this list may not work properly. Most likely reasons for this are changes in parameters, and/or data updates. If you experience any problem, please try re-running each search from the search page. You can also access the previous version of the database at v3.tdrtargets.org

Genomic scale ranking of T. brucei genes focusing on the glycolytic pathway. Published data on glycolytic flux was used to upload a weighted list of genes which was then combined with other internal datasets in TDRtargets DB.


Score for genes in query #118 (Tbr all proteins): 1
Score for genes in query #119 (Tbr in Pubmed): 20
Score for genes in query #120 (Tbr PDB structure): 20
Score for genes in query #121 (Tbr modbase structures): 10
Score for genes in query #122 (Tbr Dindex >=0.4): 20
Score for genes in query #123 (Tbr Compound desirability > 0.2): 10
Score for genes in query #124 (Tbr assayable): 20
Score for genes in query #125 (Tbr Glycolysis from KEGG): 1000
Score for genes in query #128 (uploaded weighted list of enzymes influencing glycolytic flux in Tbr): 40 to 10 (variable weight values)

Queries in this set

Click on the links below to browse the contents of each query. You can also use the checkboxes to select queries you would like to import into your history.
Import ranked queries into your history to redo the scoring strategy

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  Tbr all proteins (9153 records). Show parameters.

  Tbr in Pubmed (568 records). Show parameters.

  Tbr PDB structure (115 records). Show parameters.

  Tbr modbase structures (7119 records). Show parameters.

  Tbr Dindex >=0.4 (205 records). Show parameters.

  Tbr Compound desirability > 0.2 (175 records). Show parameters.

  Tbr assayable (350 records). Show parameters.

  Tbr Glycolysis from KEGG (32 records). Show parameters.

  uploaded weighted list of enzymes influencing glycolytic flux in Tbr (13 records). Show parameters.

  Weighted ranking of Tbr targets involved in glycolysis for PLOS-NTD-version2 (9154 records). Show parameters.