Prioritizing the Trypanosoma cruzi genome using SNPs

Posted by Alejandro Ackermann on 2010-03-04 11:15:50

WARNING: This list was made prior to the version 4 release of TDR Targets (Aug, 2010). Some queries included in this list may not work properly. Most likely reasons for this are changes in parameters, and/or data updates. If you experience any problem, please try re-running each search from the search page. You can also access the previous version of the database at v3.tdrtargets.org

We use the TDR Targets database to classify coding sequences from the Trypanosoma cruzi genome according to their nucleotide diversity and properties of interest in a target.

Queries in this set

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  Ortholog is essential in C. elegans (1281 records). Show parameters.

  Has orthologs in other trypanosomatids (7504 records). Show parameters.

  Does not have orthologs in human/mouse (20730 records). Show parameters.

  Assayability - Assay Available (334 records). Show parameters.

  Assayability - Recombinant soluble protein available (205 records). Show parameters.

  Available publications in PubMed (460 records). Show parameters.

  Mol weight is under 100kDa (22872 records). Show parameters.

  At least one trans-membrane domain (6065 records). Show parameters.

  With more than 3 copies in the genome (paralogues) (6333 records). Show parameters.

  Has a GPI anchor (predicted) (2131 records). Show parameters.

  Has a signal peptide (predicted) (4347 records). Show parameters.

  Has an annotated EC number (730 records). Show parameters.

  Non-druggable genes, ranked by an inverted nucleotide diversity score (4604 records). Show parameters.

  Union of (4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 24) (24951 records). Show parameters.