C. elegans tissue-specific gene expression, Helminths ortholog mapping

Posted by Santiago Carmona on 2011-06-10 00:09:23

Here I uploaded C. elegans Neuron and Muscle specifically expressed genes (predicted) taken from "Global Prediction of Tissue-Specific Gene Expression and Context-Dependent Gene Networks in Caenorhabditis elegans", Chikina et. al.
Both gene sets were mapped to Brugia malayi and Schistosoma mansoni genomes. These datasets can be useful for helminths drug target prioritizations.

A cut-off of one standard deviation (z>1) was used to define tissue-specifically expressed genes. C. elegans identifiers were unified with BioMart. Ortholog mapping was done using the OrthoMCL Database.

● Global prediction of tissue-specific gene expression and context-dependent gene networks in Caenorhabditis elegans. (2009). PLoS Comput Biol 5: e1000417 PubMed, Publisher.

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  B. malayi orthologs of C. elegans genes differentially expressed in muscle (519 records). Show parameters.

  S. mansoni orthologs of C. elegans genes differentially expressed in muscle (305 records). Show parameters.

  C. elegans genes differentially expressed in muscle (3131 records). Show parameters.

  S. mansoni orthologs of C. elegans genes differentially expressed in neurons (442 records). Show parameters.

  B. malayi orthologs of C. elegans genes differentially expressed in neurons (430 records). Show parameters.

  C. elegans genes differentially expressed in neurons (593 records). Show parameters.