Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
460 records found | Showing page 19 of 19 (records 451-460) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv3808c | OG5_237548 | Bifunctional UDP-galactofuranosyl transferase GlfT2 |
| M. tuberculosis | Rv3825c | OG5_126633 | Polyketide synthase Pks2 |
| M. tuberculosis | Rv3826 | OG5_127582 | Probable fatty-acid-AMP ligase FadD23 (fatty-acid-AMP synthetase) (fatty-acid-AM ... |
| M. tuberculosis | Rv3858c | OG5_126892 | Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate syn ... |
| M. tuberculosis | Rv3859c | OG5_126892 | Probable ferredoxin-dependent glutamate synthase [NADPH] (large subunit) GltB (L ... |
| M. tuberculosis | Rv3868 | OG5_132590 | ESX conserved component EccA1. ESX-1 type VII secretion system protein. |
| M. tuberculosis | Rv3878 | OG5_130758 | ESX-1 secretion-associated protein EspJ. Conserved alanine rich protein. |
| M. tuberculosis | Rv3913 | OG5_127532 | Probable thioredoxin reductase TrxB2 (TRXR) (TR) |
| M. tuberculosis | Rv3915 | OG5_226718 | Probable peptidoglycan hydrolase |
| M. tuberculosis | Rv3917c | OG5_132436 | Probable chromosome partitioning protein ParB |