Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
491 records found | Showing page 1 of 20 (records 1-25) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv0027 | No group | Conserved hypothetical protein |
| M. tuberculosis | Rv0064 | OG5_152620 | Probable conserved transmembrane protein |
| M. tuberculosis | Rv0077c | No group | Probable oxidoreductase |
| M. tuberculosis | Rv0080 | No group | Conserved hypothetical protein |
| M. tuberculosis | Rv0082 | OG5_143851 | Probable oxidoreductase |
| M. tuberculosis | Rv0094c | OG5_151920 | Conserved hypothetical protein |
| M. tuberculosis | Rv0099 | OG5_163246 | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-Co ... |
| M. tuberculosis | Rv0102 | OG5_156768 | Probable conserved integral membrane protein |
| M. tuberculosis | Rv0116c | OG5_237840 | Probable L,D-transpeptidase LdtA |
| M. tuberculosis | Rv0123 | No group | Unknown protein |
| M. tuberculosis | Rv0132c | OG5_146706 | Putative F420-dependent glucose-6-phosphate dehydrogenase Fgd2 |
| M. tuberculosis | Rv0137c | OG5_126847 | Probable peptide methionine sulfoxide reductase MsrA (protein-methionine-S-oxide ... |
| M. tuberculosis | Rv0140 | OG5_144561 | Conserved protein |
| M. tuberculosis | Rv0146 | OG5_135170 | Possible S-adenosylmethionine-dependent methyltransferase |
| M. tuberculosis | Rv0148 | OG5_129142 | Probable short-chain type dehydrogenase/reductase |
| M. tuberculosis | Rv0160c | OG5_132981 | PE family protein PE4 |
| M. tuberculosis | Rv0188 | No group | Probable conserved transmembrane protein |
| M. tuberculosis | Rv0190 | OG5_136234 | Conserved protein |
| M. tuberculosis | Rv0195 | No group | Possible two component transcriptional regulatory protein (probably LuxR-family) |
| M. tuberculosis | Rv0196 | OG5_191363 | Possible transcriptional regulatory protein |
| M. tuberculosis | Rv0197 | OG5_175709 | Possible oxidoreductase |
| M. tuberculosis | Rv0211 | OG5_129007 | Probable iron-regulated phosphoenolpyruvate carboxykinase [GTP] PckA (phosphoeno ... |
| M. tuberculosis | Rv0232 | OG5_146616 | Probable transcriptional regulatory protein (probably TetR/AcrR-family) |
| M. tuberculosis | Rv0233 | OG5_126823 | Ribonucleoside-diphosphate reductase (beta chain) NrdB (ribonucleotide reductase ... |
| M. tuberculosis | Rv0251c | OG5_126935 | Heat shock protein Hsp (heat-stress-induced ribosome-binding protein A) |