Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
23 records found | Showing page 1 of 1 (records 1-23) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv2523c | OG5_130884 | holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pant ... |
| M. tuberculosis | Rv2538c | OG5_127183 | 3-dehydroquinate synthase AroB |
| M. tuberculosis | Rv2537c | OG5_132746 | 3-dehydroquinate dehydratase AroD (AROQ) (3-dehydroquinase) (type II dhqase) |
| M. tuberculosis | Rv2068c | OG5_143180 | Class a beta-lactamase BlaC |
| M. tuberculosis | Rv0766c | OG5_132455 | Probable cytochrome P450 123 Cyp123 |
| M. tuberculosis | Rv2266 | OG5_132455 | Probable cytochrome P450 124 Cyp124 |
| M. tuberculosis | Rv2268c | OG5_132455 | Probable cytochrome P450 128 Cyp128 |
| M. tuberculosis | Rv1256c | OG5_132455 | Probable cytochrome P450 130 Cyp130 |
| M. tuberculosis | Rv3518c | OG5_132455 | Probable cytochrome P450 monooxygenase 142 Cyp142 |
| M. tuberculosis | Rv1547 | OG5_132143 | Probable DNA polymerase III (alpha chain) DnaE1 (DNA nucleotidyltransferase) |
| M. tuberculosis | Rv0533c | OG5_129509 | 3-oxoacyl-[acyl-carrier-protein] synthase III FabH (beta-ketoacyl-ACP synthase I ... |
| M. tuberculosis | Rv3804c | OG5_210859 | Secreted antigen 85-a FbpA (mycolyl transferase 85A) (fibronectin-binding protei ... |
| M. tuberculosis | Rv1886c | OG5_237749 | Secreted antigen 85-B FbpB (85B) (antigen 85 complex B) (mycolyl transferase 85B ... |
| M. tuberculosis | Rv0129c | OG5_237839 | Secreted antigen 85-C FbpC (85C) (antigen 85 complex C) (AG58C) (mycolyl transfe ... |
| M. tuberculosis | Rv3803c | OG5_237550 | Secreted MPT51/MPB51 antigen protein FbpD (MPT51/MPB51 antigen 85 complex C) (AG ... |
| M. tuberculosis | Rv1601 | OG5_129258 | Probable imidazole glycerol-phosphate dehydratase HisB |
| M. tuberculosis | Rv1484 | OG5_130466 | NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl ... |
| M. tuberculosis | Rv0091 | OG5_130719 | Probable bifunctional MTA/SAH nucleosidase Mtn: 5'-methylthioadenosine nucleosid ... |
| M. tuberculosis | Rv2157c | OG5_132578 | Probable UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-al ... |
| M. tuberculosis | Rv2156c | OG5_131597 | Probable phospho-N-acetylmuramoyl-pentappeptidetransferase MurX |
| M. tuberculosis | Rv0769 | OG5_169253 | Probable dehydrogenase/reductase |
| M. tuberculosis | Rv1523 | OG5_176228 | Probable methyltransferase |
| M. tuberculosis | Rv2952 | OG5_149693 | Possible methyltransferase (methylase) |