Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
460 records found | Showing page 17 of 19 (records 401-425) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product |
---|---|---|---|
M. tuberculosis | Rv3441c | OG5_128112 | Probable phospho-sugar mutase / MrsA protein homolog |
M. tuberculosis | Rv3457c | OG5_130460 | Probable DNA-directed RNA polymerase (alpha chain) RpoA (transcriptase alpha cha ... |
M. tuberculosis | Rv3458c | OG5_131566 | 30S ribosomal protein S4 RpsD |
M. tuberculosis | Rv3459c | OG5_126681 | 30S ribosomal protein S11 RpsK |
M. tuberculosis | Rv3462c | OG5_130791 | Probable translation initiation factor if-1 InfA |
M. tuberculosis | Rv3464 | OG5_127949 | dTDP-glucose 4,6-dehydratase RmlB |
M. tuberculosis | Rv3465 | OG5_132926 | dTDP-4-dehydrorhamnose 3,5-epimerase RmlC (dTDP-4-keto-6-deoxyglucose 3,5-epimer ... |
M. tuberculosis | Rv3490 | OG5_129327 | Alpha, alpha-trehalose-phosphate synthase [UDP-forming] OtsA (trehalose-6-phosph ... |
M. tuberculosis | Rv3501c | OG5_130961 | Conserved integral membrane protein YrbE4A. Possible ABC transporter. |
M. tuberculosis | Rv3518c | OG5_132455 | Probable cytochrome P450 monooxygenase 142 Cyp142 |
M. tuberculosis | Rv3538 | OG5_129142 | Probable dehydrogenase. Possible 2-enoyl acyl-CoA hydratase. |
M. tuberculosis | Rv3545c | OG5_132455 | Probable cytochrome P450 125 Cyp125 |
M. tuberculosis | Rv3558 | OG5_132376 | PPE family protein PPE64 |
M. tuberculosis | Rv3559c | OG5_168406 | Probable oxidoreductase |
M. tuberculosis | Rv3561 | OG5_126609 | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA ... |
M. tuberculosis | Rv3563 | OG5_156898 | Probable acyl-CoA dehydrogenase FadE32 |
M. tuberculosis | Rv3564 | OG5_156898 | Probable acyl-CoA dehydrogenase FadE33 |
M. tuberculosis | Rv3579c | OG5_128345 | Possible tRNA/rRNA methyltransferase |
M. tuberculosis | Rv3596c | OG5_126636 | Probable ATP-dependent protease ATP-binding subunit ClpC1 |
M. tuberculosis | Rv3597c | OG5_237569 | Iron-regulated H-NS-like protein Lsr2 |
M. tuberculosis | Rv3602c | OG5_129569 | Pantoate--beta-alanine ligase PanC (pantothenate synthetase) (pantoate activatin ... |
M. tuberculosis | Rv3604c | OG5_237568 | Probable conserved transmembrane protein rich in alanine and arginine and prolin ... |
M. tuberculosis | Rv3607c | OG5_133572 | Probable dihydroneopterin aldolase FolB (DHNA) |
M. tuberculosis | Rv3609c | OG5_127507 | GTP cyclohydrolase I FolE (GTP-ch-I) |
M. tuberculosis | Rv3610c | OG5_126616 | Membrane-bound protease FtsH (cell division protein) |