Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
491 records found | Showing page 2 of 20 (records 26-50) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv0260c | No group | Possible transcriptional regulatory protein |
| M. tuberculosis | Rv0267 | OG5_135256 | Probable integral membrane nitrite extrusion protein NarU (nitrite facilitator) |
| M. tuberculosis | Rv0275c | OG5_179227 | Possible transcriptional regulatory protein (possibly TetR-family) |
| M. tuberculosis | Rv0277c | OG5_166865 | Possible toxin VapC25. Contains PIN domain. |
| M. tuberculosis | Rv0282 | OG5_132590 | ESX conserved component EccA3. ESX-3 type VII secretion system protein. |
| M. tuberculosis | Rv0293c | OG5_239110 | Conserved protein |
| M. tuberculosis | Rv0300 | No group | Possible antitoxin VapB2 |
| M. tuberculosis | Rv0324 | OG5_141282 | Possible transcriptional regulatory protein (possibly ArsR-family) |
| M. tuberculosis | Rv0330c | No group | Hypothetical protein |
| M. tuberculosis | Rv0331 | OG5_129122 | Possible dehydrogenase/reductase |
| M. tuberculosis | Rv0342 | No group | Isoniazid inductible gene protein IniA |
| M. tuberculosis | Rv0350 | OG5_126744 | Probable chaperone protein DnaK (heat shock protein 70) (heat shock 70 kDa prote ... |
| M. tuberculosis | Rv0352 | OG5_126952 | Probable chaperone protein DnaJ1 |
| M. tuberculosis | Rv0355c | OG5_132376 | PPE family protein PPE8 |
| M. tuberculosis | Rv0376c | OG5_138104 | Conserved hypothetical protein |
| M. tuberculosis | Rv0388c | OG5_135481 | PPE family protein PPE9 |
| M. tuberculosis | Rv0426c | OG5_237735 | Possible transmembrane protein |
| M. tuberculosis | Rv0440 | OG5_126788 | 60 kDa chaperonin 2 GroEL2 (protein CPN60-2) (GroEL protein 2) (65 kDa antigen) ... |
| M. tuberculosis | Rv0467 | OG5_129572 | Isocitrate lyase Icl (isocitrase) (isocitratase) |
| M. tuberculosis | Rv0474 | OG5_191152 | Probable transcriptional regulatory protein |
| M. tuberculosis | Rv0476 | OG5_237810 | Possible conserved transmembrane protein |
| M. tuberculosis | Rv0515 | OG5_166864 | Conserved 13E12 repeat family protein |
| M. tuberculosis | Rv0516c | OG5_184388 | Possible anti-anti-sigma factor |
| M. tuberculosis | Rv0521 | No group | POSSIBLE METHYLTRANSFERASE/METHYLASE (FRAGMENT) |
| M. tuberculosis | Rv0563 | OG5_131984 | Probable protease transmembrane protein heat shock protein HtpX |