Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
471 records found | Showing page 2 of 19 (records 26-50) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv0211 | OG5_129007 | Probable iron-regulated phosphoenolpyruvate carboxykinase [GTP] PckA (phosphoeno ... |
| M. tuberculosis | Rv0223c | OG5_137356 | Probable aldehyde dehydrogenase |
| M. tuberculosis | Rv0251c | OG5_126935 | Heat shock protein Hsp (heat-stress-induced ribosome-binding protein A) |
| M. tuberculosis | Rv0252 | OG5_126784 | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB |
| M. tuberculosis | Rv0258c | No group | Conserved hypothetical protein |
| M. tuberculosis | Rv0264c | OG5_138055 | Conserved hypothetical protein |
| M. tuberculosis | Rv0275c | OG5_179227 | Possible transcriptional regulatory protein (possibly TetR-family) |
| M. tuberculosis | Rv0294 | OG5_147019 | Probable trans-aconitate methyltransferase Tam |
| M. tuberculosis | Rv0309 | OG5_156934 | Possible conserved exported protein |
| M. tuberculosis | Rv0323c | OG5_128077 | Conserved hypothetical protein |
| M. tuberculosis | Rv0330c | No group | Hypothetical protein |
| M. tuberculosis | Rv0331 | OG5_129122 | Possible dehydrogenase/reductase |
| M. tuberculosis | Rv0341 | OG5_146536 | Isoniazid inductible gene protein IniB |
| M. tuberculosis | Rv0342 | No group | Isoniazid inductible gene protein IniA |
| M. tuberculosis | Rv0350 | OG5_126744 | Probable chaperone protein DnaK (heat shock protein 70) (heat shock 70 kDa prote ... |
| M. tuberculosis | Rv0361 | OG5_237574 | Probable conserved membrane protein |
| M. tuberculosis | Rv0371c | OG5_141298 | Conserved hypothetical protein |
| M. tuberculosis | Rv0373c | OG5_127252 | Probable carbon monoxyde dehydrogenase (large chain) |
| M. tuberculosis | Rv0376c | OG5_138104 | Conserved hypothetical protein |
| M. tuberculosis | Rv0383c | OG5_237813 | Possible conserved secreted protein |
| M. tuberculosis | Rv0386 | OG5_160474 | Probable transcriptional regulatory protein (probably LuxR/UhpA-family) |
| M. tuberculosis | Rv0426c | OG5_237735 | Possible transmembrane protein |
| M. tuberculosis | Rv0455c | OG5_237795 | Conserved protein |
| M. tuberculosis | Rv0467 | OG5_129572 | Isocitrate lyase Icl (isocitrase) (isocitratase) |
| M. tuberculosis | Rv0474 | OG5_191152 | Probable transcriptional regulatory protein |