Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
783 records found | Showing page 2 of 32 (records 26-50) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv2552c | OG5_128849 | Probable shikimate 5-dehydrogenase AroE (5-dehydroshikimate reductase) |
| M. tuberculosis | Rv2178c | OG5_130802 | 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroG (DAHP synthetase, phen ... |
| M. tuberculosis | Rv2539c | OG5_130547 | Shikimate kinase AroK (SK) |
| M. tuberculosis | Rv3708c | OG5_128664 | Aspartate-semialdehyde dehydrogenase Asd (ASA dehydrogenase) (ASADH) (aspartic s ... |
| M. tuberculosis | Rv1308 | OG5_127165 | Probable ATP synthase alpha chain AtpA |
| M. tuberculosis | Rv1304 | OG5_128903 | Probable ATP synthase a chain AtpB (protein 6) |
| M. tuberculosis | Rv1311 | OG5_127404 | Probable ATP synthase epsilon chain AtpC |
| M. tuberculosis | Rv1310 | OG5_127099 | Probable ATP synthase beta chain AtpD |
| M. tuberculosis | Rv1305 | OG5_126818 | Probable ATP synthase C chain AtpE (lipid-binding protein) (dicyclohexylcarbodii ... |
| M. tuberculosis | Rv1306 | OG5_134191 | Probable ATP synthase B chain AtpF |
| M. tuberculosis | Rv1309 | OG5_127077 | Probable ATP synthase gamma chain AtpG |
| M. tuberculosis | Rv1307 | OG5_134191 | Probable ATP synthase delta chain AtpH |
| M. tuberculosis | Rv0711 | OG5_126989 | Possible arylsulfatase AtsA (aryl-sulfate sulphohydrolase) (arylsulphatase) |
| M. tuberculosis | Rv0663 | OG5_197445 | Possible arylsulfatase AtsD (aryl-sulfate sulphohydrolase) (arylsulphatase) |
| M. tuberculosis | Rv1568 | OG5_128068 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA |
| M. tuberculosis | Rv1569 | OG5_126783 | Probable 8-amino-7-oxononanoate synthase BioF1 (AONS) (8-amino-7-ketopelargonate ... |
| M. tuberculosis | Rv0032 | OG5_126783 | Possible 8-amino-7-oxononanoate synthase BioF2 (AONS) (8-amino-7-ketopelargonate ... |
| M. tuberculosis | Rv1442 | OG5_140519 | Probable biotin sulfoxide reductase BisC (BDS reductase) (BSO reductase) |
| M. tuberculosis | Rv2068c | OG5_143180 | Class a beta-lactamase BlaC |
| M. tuberculosis | Rv1123c | OG5_152322 | Possible peroxidase BpoB (non-haem peroxidase) |
| M. tuberculosis | Rv1077 | OG5_126662 | Probable cystathionine beta-synthase Cbs (serine sulfhydrase) (beta-thionase) (h ... |
| M. tuberculosis | Rv3315c | OG5_127381 | Probable cytidine deaminase Cdd (cytidine aminohydrolase) (cytidine nucleoside d ... |
| M. tuberculosis | Rv0062 | OG5_137267 | Possible cellulase CelA1 (endoglucanase) (endo-1,4-beta-glucanase) (FI-cmcase) ( ... |
| M. tuberculosis | Rv2691 | OG5_208986 | TRK system potassium uptake protein CeoB |
| M. tuberculosis | Rv1984c | OG5_136129 | Probable cutinase precursor CFP21 |